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Overview

ID MAG00439
Name CMS2_bin.50
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family SG8-41
Genus SG8-41
Species
Assembly information
Completeness (%) 76.34
Contamination (%) 2.34
GC content (%) 63.0
N50 (bp) 35,096
Genome size (bp) 3,075,708

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2866

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1068331_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1262.0
CMS2_k127_1068331_1 Protein of unknown function - - - 0.0 1195.0
CMS2_k127_1068331_10 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 505.0
CMS2_k127_1068331_11 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 498.0
CMS2_k127_1068331_12 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 491.0
CMS2_k127_1068331_13 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008116 490.0
CMS2_k127_1068331_14 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 462.0
CMS2_k127_1068331_15 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 420.0
CMS2_k127_1068331_16 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 408.0
CMS2_k127_1068331_17 Dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 396.0
CMS2_k127_1068331_18 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007312 386.0
CMS2_k127_1068331_19 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 365.0
CMS2_k127_1068331_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 5.749e-316 990.0
CMS2_k127_1068331_20 interspecies interaction between organisms - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 350.0
CMS2_k127_1068331_21 (2R)-phospho-3-sulfolactate synthase (ComA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 347.0
CMS2_k127_1068331_22 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 346.0
CMS2_k127_1068331_23 Probable molybdopterin binding domain K03638,K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 310.0
CMS2_k127_1068331_24 Serine hydrolase (FSH1) K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 292.0
CMS2_k127_1068331_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009614 271.0
CMS2_k127_1068331_26 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000549 246.0
CMS2_k127_1068331_27 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000001072 235.0
CMS2_k127_1068331_28 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000001435 227.0
CMS2_k127_1068331_29 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000004047 223.0
CMS2_k127_1068331_3 FAD dependent oxidoreductase - - - 2.54e-231 726.0
CMS2_k127_1068331_30 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000002304 212.0
CMS2_k127_1068331_31 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000003135 213.0
CMS2_k127_1068331_32 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000006969 196.0
CMS2_k127_1068331_33 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000009004 197.0
CMS2_k127_1068331_34 Cupin domain - - - 0.0000000000000000000000000000000000000000001511 163.0
CMS2_k127_1068331_35 SnoaL-like domain - - - 0.0000000000000000000000000000000000002213 146.0
CMS2_k127_1068331_36 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000007225 143.0
CMS2_k127_1068331_37 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000007644 144.0
CMS2_k127_1068331_38 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000007985 137.0
CMS2_k127_1068331_39 Zinc-finger domain - - - 0.000000000000000000000000000001708 121.0
CMS2_k127_1068331_4 modulator of DNA gyrase K03568 - - 3.695e-220 691.0
CMS2_k127_1068331_40 - - - - 0.00000000000000000000000166 108.0
CMS2_k127_1068331_5 alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 2.567e-215 676.0
CMS2_k127_1068331_6 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 7.691e-197 625.0
CMS2_k127_1068331_7 peptidase U62, modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 612.0
CMS2_k127_1068331_8 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 569.0
CMS2_k127_1068331_9 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 566.0
CMS2_k127_1105232_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1528.0
CMS2_k127_1105232_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.93e-297 921.0
CMS2_k127_1105232_10 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 316.0
CMS2_k127_1105232_11 Beta-lactamase enzyme family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 296.0
CMS2_k127_1105232_12 Two component transcriptional regulator, winged helix family K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 293.0
CMS2_k127_1105232_13 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 293.0
CMS2_k127_1105232_14 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 286.0
CMS2_k127_1105232_15 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000000002124 219.0
CMS2_k127_1105232_16 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000383 218.0
CMS2_k127_1105232_17 Flagellar Assembly Protein A K09749 - - 0.00000000000000000000000000000000000000000000000000000005999 210.0
CMS2_k127_1105232_18 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000002326 171.0
CMS2_k127_1105232_19 domain, Protein K13735,K15125,K15531 - 3.2.1.156 0.00000000000000000000000000000000000000001774 164.0
CMS2_k127_1105232_2 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 5.917e-243 767.0
CMS2_k127_1105232_20 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000006361 152.0
CMS2_k127_1105232_21 Guanyl-specific ribonuclease Sa K01167 - 3.1.27.3 0.000000000000000000000000000000000156 136.0
CMS2_k127_1105232_22 Putative regulatory protein - - - 0.00000000000000000000000000002262 120.0
CMS2_k127_1105232_23 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000006478 113.0
CMS2_k127_1105232_24 (barnase) inhibitor - - - 0.000000000000000000006441 97.0
CMS2_k127_1105232_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 607.0
CMS2_k127_1105232_4 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 531.0
CMS2_k127_1105232_5 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 506.0
CMS2_k127_1105232_6 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 474.0
CMS2_k127_1105232_7 Methyl-transferase K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 378.0
CMS2_k127_1105232_8 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 375.0
CMS2_k127_1105232_9 PFAM Endonuclease exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 357.0
CMS2_k127_1116705_0 SNARE associated Golgi protein - - - 0.0 1062.0
CMS2_k127_1116705_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.469e-300 931.0
CMS2_k127_1116705_10 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 317.0
CMS2_k127_1116705_11 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 310.0
CMS2_k127_1116705_12 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 299.0
CMS2_k127_1116705_13 Glycosyl transferase group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 289.0
CMS2_k127_1116705_14 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003095 296.0
CMS2_k127_1116705_15 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000003227 223.0
CMS2_k127_1116705_16 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000000000000000000000000000000000007199 209.0
CMS2_k127_1116705_17 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000001927 193.0
CMS2_k127_1116705_18 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000003249 113.0
CMS2_k127_1116705_19 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000008584 91.0
CMS2_k127_1116705_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 2.21e-228 718.0
CMS2_k127_1116705_20 Transcriptional regulator K13634 - - 0.000000000000000003572 85.0
CMS2_k127_1116705_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 6.454e-216 676.0
CMS2_k127_1116705_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 610.0
CMS2_k127_1116705_5 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 544.0
CMS2_k127_1116705_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 509.0
CMS2_k127_1116705_7 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 481.0
CMS2_k127_1116705_8 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 461.0
CMS2_k127_1116705_9 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 416.0
CMS2_k127_1128713_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 6.632e-230 728.0
CMS2_k127_1128713_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 3.67e-225 722.0
CMS2_k127_1128713_10 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008528 277.0
CMS2_k127_1128713_11 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000002825 268.0
CMS2_k127_1128713_12 MarC family integral membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000002256 217.0
CMS2_k127_1128713_13 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000001026 197.0
CMS2_k127_1128713_14 FCD - - - 0.000000000000000000000000000000000000000000000000000001473 200.0
CMS2_k127_1128713_15 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000000000000000000000000000004446 189.0
CMS2_k127_1128713_16 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000000000007397 166.0
CMS2_k127_1128713_17 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000001156 159.0
CMS2_k127_1128713_18 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.00000000000000000000000002057 110.0
CMS2_k127_1128713_19 Protein of unknown function (DUF465) - - - 0.0000000000002328 72.0
CMS2_k127_1128713_2 Metallopeptidase family M24 - - - 1.259e-194 616.0
CMS2_k127_1128713_20 COG3909 Cytochrome c556 - - - 0.00000006491 61.0
CMS2_k127_1128713_21 - - - - 0.00006771 53.0
CMS2_k127_1128713_3 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 517.0
CMS2_k127_1128713_4 NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 508.0
CMS2_k127_1128713_5 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 440.0
CMS2_k127_1128713_6 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 411.0
CMS2_k127_1128713_7 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 344.0
CMS2_k127_1128713_8 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 315.0
CMS2_k127_1128713_9 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003364 282.0
CMS2_k127_1162080_0 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 600.0
CMS2_k127_1162080_1 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 544.0
CMS2_k127_1162080_2 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 481.0
CMS2_k127_1162080_3 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 362.0
CMS2_k127_1162080_4 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001977 274.0
CMS2_k127_1162080_5 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.00000000000000000000000000000000000000000000000000000000000000000002621 235.0
CMS2_k127_1162080_6 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.0000000000000000000000000006621 115.0
CMS2_k127_1162080_7 Predicted nucleotide-binding protein containing TIR-like domain - - - 0.00000000000000000000002057 105.0
CMS2_k127_1162080_8 PilZ domain - - - 0.0000000001283 66.0
CMS2_k127_1195277_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1384.0
CMS2_k127_1195277_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 9.354e-272 851.0
CMS2_k127_1195277_10 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000006323 252.0
CMS2_k127_1195277_11 Glycine zipper - - - 0.000000000000000000000000000000000000000000000000000000000007793 216.0
CMS2_k127_1195277_12 Drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000006515 204.0
CMS2_k127_1195277_13 NnrU protein - - - 0.000000000000000000000000000000000000000000000000000002215 212.0
CMS2_k127_1195277_14 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000000001429 152.0
CMS2_k127_1195277_15 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000531 128.0
CMS2_k127_1195277_16 Uncharacterized protein conserved in bacteria (DUF2314) - - - 0.0000000000000000000000003861 112.0
CMS2_k127_1195277_17 Universal stress protein family - - - 0.0000000000000000000002097 102.0
CMS2_k127_1195277_18 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000005109 99.0
CMS2_k127_1195277_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 599.0
CMS2_k127_1195277_3 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 538.0
CMS2_k127_1195277_4 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 434.0
CMS2_k127_1195277_5 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 369.0
CMS2_k127_1195277_6 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 317.0
CMS2_k127_1195277_7 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 314.0
CMS2_k127_1195277_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004624 274.0
CMS2_k127_1195277_9 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001298 271.0
CMS2_k127_1206375_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.219e-279 867.0
CMS2_k127_1206375_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 595.0
CMS2_k127_1206375_10 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001801 274.0
CMS2_k127_1206375_11 - - - - 0.00002599 49.0
CMS2_k127_1206375_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 520.0
CMS2_k127_1206375_3 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 450.0
CMS2_k127_1206375_4 AcnD-accessory protein PrpF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 438.0
CMS2_k127_1206375_5 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 401.0
CMS2_k127_1206375_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 355.0
CMS2_k127_1206375_7 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 339.0
CMS2_k127_1206375_8 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 334.0
CMS2_k127_1206375_9 TIGRFAM squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 330.0
CMS2_k127_1239926_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 6.405e-286 885.0
CMS2_k127_1239926_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.556e-212 677.0
CMS2_k127_1239926_10 fructose-bisphosphate aldolase K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 445.0
CMS2_k127_1239926_11 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 379.0
CMS2_k127_1239926_12 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 339.0
CMS2_k127_1239926_13 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 327.0
CMS2_k127_1239926_14 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
CMS2_k127_1239926_15 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000399 282.0
CMS2_k127_1239926_16 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002288 259.0
CMS2_k127_1239926_17 PFAM cation efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002099 256.0
CMS2_k127_1239926_18 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 257.0
CMS2_k127_1239926_19 Electron transfer flavoprotein FAD-binding domain K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000001595 231.0
CMS2_k127_1239926_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.053e-208 669.0
CMS2_k127_1239926_20 electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000002725 216.0
CMS2_k127_1239926_21 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001993 209.0
CMS2_k127_1239926_22 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000007847 189.0
CMS2_k127_1239926_23 Mo-co oxidoreductase dimerisation domain K00387 - 1.8.3.1 0.000000000000000000000000000000000000000000000000008675 196.0
CMS2_k127_1239926_24 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000000000000000000001093 176.0
CMS2_k127_1239926_25 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000018 171.0
CMS2_k127_1239926_27 Methyltransferase - - - 0.0000000000000000000000000000000000001097 153.0
CMS2_k127_1239926_28 peptidase - - - 0.000000000000000000000000000000001656 140.0
CMS2_k127_1239926_29 Methyltransferase domain - - - 0.00000000000000000000000000002156 117.0
CMS2_k127_1239926_3 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 6.041e-206 655.0
CMS2_k127_1239926_30 - - - - 0.0000000000000000000000000001909 126.0
CMS2_k127_1239926_31 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.0000000000000000000000000006093 121.0
CMS2_k127_1239926_32 Thioesterase superfamily K18700 - 3.1.2.29 0.00000000000000000000000003123 113.0
CMS2_k127_1239926_34 - - - - 0.00000000000000000000000678 113.0
CMS2_k127_1239926_35 - - - - 0.0000000000000000003423 92.0
CMS2_k127_1239926_36 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.00000000000001108 85.0
CMS2_k127_1239926_4 Carboxyl transferase domain - - - 8.004e-206 651.0
CMS2_k127_1239926_5 Biotin carboxylase C-terminal domain K01941 - 6.3.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 574.0
CMS2_k127_1239926_6 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 547.0
CMS2_k127_1239926_7 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 538.0
CMS2_k127_1239926_8 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 483.0
CMS2_k127_1239926_9 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 469.0
CMS2_k127_1243441_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 548.0
CMS2_k127_1243441_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 451.0
CMS2_k127_1243441_2 COG3344 Retron-type reverse transcriptase - - - 0.0000000000000000000000000000007505 125.0
CMS2_k127_1243441_3 - - - - 0.000000000000000000006385 96.0
CMS2_k127_1243441_4 Ankyrin repeats (many copies) - - - 0.0008741 42.0
CMS2_k127_1301117_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 416.0
CMS2_k127_1301117_1 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000002809 246.0
CMS2_k127_1301117_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000001029 229.0
CMS2_k127_1301117_3 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000396 194.0
CMS2_k127_1401334_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1082.0
CMS2_k127_1401334_1 DNA topoisomerase III K03169 - 5.99.1.2 0.0 1082.0
CMS2_k127_1401334_10 PFAM Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 323.0
CMS2_k127_1401334_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000004215 247.0
CMS2_k127_1401334_12 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000001471 164.0
CMS2_k127_1401334_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.227e-295 920.0
CMS2_k127_1401334_3 Histidine kinase - - - 1.13e-237 764.0
CMS2_k127_1401334_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 586.0
CMS2_k127_1401334_5 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 526.0
CMS2_k127_1401334_6 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 476.0
CMS2_k127_1401334_7 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 408.0
CMS2_k127_1401334_8 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 379.0
CMS2_k127_1401334_9 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 342.0
CMS2_k127_148381_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.239e-219 694.0
CMS2_k127_148381_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.378e-216 684.0
CMS2_k127_148381_10 Multidrug transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 445.0
CMS2_k127_148381_11 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 405.0
CMS2_k127_148381_12 abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 402.0
CMS2_k127_148381_13 OmpA MotB K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 406.0
CMS2_k127_148381_14 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 398.0
CMS2_k127_148381_15 Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 398.0
CMS2_k127_148381_16 PFAM transcriptional regulator domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 414.0
CMS2_k127_148381_17 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 377.0
CMS2_k127_148381_18 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 372.0
CMS2_k127_148381_19 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 359.0
CMS2_k127_148381_2 Peptidase M50 K16922 - - 2.116e-211 679.0
CMS2_k127_148381_20 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 356.0
CMS2_k127_148381_21 MotA TolQ ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 361.0
CMS2_k127_148381_22 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 347.0
CMS2_k127_148381_23 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 339.0
CMS2_k127_148381_24 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 327.0
CMS2_k127_148381_25 Carbon-nitrogen hydrolase K01501,K01502 - 3.5.5.1,3.5.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 331.0
CMS2_k127_148381_26 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 328.0
CMS2_k127_148381_27 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 324.0
CMS2_k127_148381_28 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 331.0
CMS2_k127_148381_29 auxin efflux carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 318.0
CMS2_k127_148381_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.765e-205 656.0
CMS2_k127_148381_30 50S ribosomal protein L4 K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 295.0
CMS2_k127_148381_31 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 295.0
CMS2_k127_148381_32 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008677 277.0
CMS2_k127_148381_33 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001972 281.0
CMS2_k127_148381_34 dehydratase K18290 - 4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006597 271.0
CMS2_k127_148381_35 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007149 266.0
CMS2_k127_148381_36 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001607 273.0
CMS2_k127_148381_37 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003671 267.0
CMS2_k127_148381_38 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003847 251.0
CMS2_k127_148381_39 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000002764 239.0
CMS2_k127_148381_4 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 573.0
CMS2_k127_148381_40 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004192 243.0
CMS2_k127_148381_41 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000001725 233.0
CMS2_k127_148381_42 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003627 240.0
CMS2_k127_148381_43 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000001968 224.0
CMS2_k127_148381_44 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000002411 211.0
CMS2_k127_148381_45 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000004901 210.0
CMS2_k127_148381_47 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.0000000000000000000000000000000000000000000000000000000002259 207.0
CMS2_k127_148381_48 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000001381 193.0
CMS2_k127_148381_49 MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000002889 205.0
CMS2_k127_148381_5 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 547.0
CMS2_k127_148381_50 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000001764 195.0
CMS2_k127_148381_51 Bacterial extracellular solute-binding protein K22003 - 5.3.3.7 0.0000000000000000000000000000000000000000000000000001984 193.0
CMS2_k127_148381_52 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000005461 186.0
CMS2_k127_148381_53 NmrA-like family - - - 0.000000000000000000000000000000000000000000000002637 185.0
CMS2_k127_148381_54 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000003766 187.0
CMS2_k127_148381_55 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000000001401 173.0
CMS2_k127_148381_56 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000003646 175.0
CMS2_k127_148381_57 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000004316 169.0
CMS2_k127_148381_58 COG2199 FOG GGDEF domain - - - 0.000000000000000000000000000000000000000000003201 178.0
CMS2_k127_148381_59 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000008738 162.0
CMS2_k127_148381_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 510.0
CMS2_k127_148381_60 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000004253 157.0
CMS2_k127_148381_61 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000306 153.0
CMS2_k127_148381_62 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000000000001319 150.0
CMS2_k127_148381_63 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000001378 147.0
CMS2_k127_148381_64 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000001505 144.0
CMS2_k127_148381_65 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000001372 138.0
CMS2_k127_148381_66 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000002716 139.0
CMS2_k127_148381_67 Universal stress protein - - - 0.00000000000000000000000000000006324 132.0
CMS2_k127_148381_68 Class ii aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000003885 131.0
CMS2_k127_148381_69 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000002161 124.0
CMS2_k127_148381_7 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 509.0
CMS2_k127_148381_70 Periplasmic lysozyme inhibitor of I-type lysozyme - - - 0.00000000000000000000000000001159 125.0
CMS2_k127_148381_71 Ribosomal protein L30p/L7e K02907 - - 0.000000000000000000001808 94.0
CMS2_k127_148381_72 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000000004683 93.0
CMS2_k127_148381_73 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000429 98.0
CMS2_k127_148381_74 - - - - 0.0000000000000000006661 96.0
CMS2_k127_148381_75 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000002177 80.0
CMS2_k127_148381_76 Sel1-like repeats. K07126,K13582 - - 0.000000000000002285 85.0
CMS2_k127_148381_77 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000002467 70.0
CMS2_k127_148381_78 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000001958 66.0
CMS2_k127_148381_79 PFAM Cyclic nucleotide-binding - - - 0.0000000007601 66.0
CMS2_k127_148381_8 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 496.0
CMS2_k127_148381_80 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000002807 57.0
CMS2_k127_148381_81 - - - - 0.0000946 50.0
CMS2_k127_148381_9 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 441.0
CMS2_k127_1499181_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 1.981e-273 850.0
CMS2_k127_1499181_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 471.0
CMS2_k127_1499181_10 - - - - 0.00001694 53.0
CMS2_k127_1499181_11 - - - - 0.0001216 51.0
CMS2_k127_1499181_2 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 374.0
CMS2_k127_1499181_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 321.0
CMS2_k127_1499181_4 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000003062 201.0
CMS2_k127_1499181_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000003341 159.0
CMS2_k127_1499181_6 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000000000000000003445 149.0
CMS2_k127_1499181_7 methyltransferase - - - 0.000000000000000000000000000002664 124.0
CMS2_k127_1499181_8 Domain of unknown function (DUF1330) - - - 0.0000000000000000001127 91.0
CMS2_k127_1499181_9 - - - - 0.000000000009625 64.0
CMS2_k127_1510060_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.5e-323 1003.0
CMS2_k127_1510060_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 5.12e-259 803.0
CMS2_k127_1510060_10 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 482.0
CMS2_k127_1510060_11 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 391.0
CMS2_k127_1510060_12 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 385.0
CMS2_k127_1510060_13 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 327.0
CMS2_k127_1510060_14 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 329.0
CMS2_k127_1510060_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 312.0
CMS2_k127_1510060_16 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 304.0
CMS2_k127_1510060_17 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 288.0
CMS2_k127_1510060_18 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 293.0
CMS2_k127_1510060_19 ATPase MipZ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008567 275.0
CMS2_k127_1510060_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 1.847e-257 808.0
CMS2_k127_1510060_20 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000178 273.0
CMS2_k127_1510060_21 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001417 252.0
CMS2_k127_1510060_22 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000000000003801 231.0
CMS2_k127_1510060_23 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000006481 219.0
CMS2_k127_1510060_24 cyclic nucleotide binding K01420 - - 0.00000000000000000000000000000000000000000000000000000007635 205.0
CMS2_k127_1510060_25 LysR family - - - 0.000000000000000000000000000000000000000000001656 173.0
CMS2_k127_1510060_26 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000001379 159.0
CMS2_k127_1510060_27 Staphylococcal nuclease homologues - - - 0.00000000000000000000000000000000000002087 151.0
CMS2_k127_1510060_28 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000001779 120.0
CMS2_k127_1510060_29 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000000001313 108.0
CMS2_k127_1510060_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.21e-227 714.0
CMS2_k127_1510060_30 - - - - 0.0000000000002467 70.0
CMS2_k127_1510060_32 Sulfite exporter TauE/SafE K07090 - - 0.000003371 57.0
CMS2_k127_1510060_33 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0001267 49.0
CMS2_k127_1510060_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.037e-225 713.0
CMS2_k127_1510060_5 COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase Amino acid transport and metabolism Coenzyme metabolism K01652 - 2.2.1.6 6.583e-220 696.0
CMS2_k127_1510060_6 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.005e-211 666.0
CMS2_k127_1510060_7 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 3.015e-209 662.0
CMS2_k127_1510060_8 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 556.0
CMS2_k127_1510060_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 496.0
CMS2_k127_1526430_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1597.0
CMS2_k127_1526430_1 MMPL family - - - 0.0 1327.0
CMS2_k127_1526430_10 Phosphatase K01090 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 476.0
CMS2_k127_1526430_11 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 467.0
CMS2_k127_1526430_12 synthase component I K01665 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 437.0
CMS2_k127_1526430_13 Psort location CytoplasmicMembrane, score 10.00 K03458 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 446.0
CMS2_k127_1526430_14 Psort location CytoplasmicMembrane, score 10.00 K03458 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 434.0
CMS2_k127_1526430_15 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 417.0
CMS2_k127_1526430_16 Permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 422.0
CMS2_k127_1526430_17 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 390.0
CMS2_k127_1526430_18 Glutathione S-transferase, N-terminal domain K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 384.0
CMS2_k127_1526430_19 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 362.0
CMS2_k127_1526430_2 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1124.0
CMS2_k127_1526430_20 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 349.0
CMS2_k127_1526430_21 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 344.0
CMS2_k127_1526430_22 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 320.0
CMS2_k127_1526430_23 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 310.0
CMS2_k127_1526430_24 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 310.0
CMS2_k127_1526430_25 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 296.0
CMS2_k127_1526430_26 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 294.0
CMS2_k127_1526430_27 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K17202,K17205,K17213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003636 286.0
CMS2_k127_1526430_28 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006778 274.0
CMS2_k127_1526430_29 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001765 256.0
CMS2_k127_1526430_3 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.563e-268 835.0
CMS2_k127_1526430_30 Pfam Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002191 256.0
CMS2_k127_1526430_31 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000006892 237.0
CMS2_k127_1526430_32 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000002738 235.0
CMS2_k127_1526430_33 PFAM regulatory protein AsnC Lrp family K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000008244 216.0
CMS2_k127_1526430_34 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000002746 216.0
CMS2_k127_1526430_35 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000614 205.0
CMS2_k127_1526430_36 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000004216 199.0
CMS2_k127_1526430_37 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000003904 198.0
CMS2_k127_1526430_38 Cysteine-rich motif following a subset of SET domains K07117 - - 0.000000000000000000000000000000000000000000000003789 176.0
CMS2_k127_1526430_39 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000005685 175.0
CMS2_k127_1526430_4 Serine aminopeptidase, S33 - - - 4.57e-249 780.0
CMS2_k127_1526430_40 Membrane K15977 - - 0.00000000000000000000000000000000000000000002257 166.0
CMS2_k127_1526430_41 Bacterial PH domain - - - 0.00000000000000000000000000000000000003182 147.0
CMS2_k127_1526430_42 membrane K15977 - - 0.0000000000000000000000000000000000001545 148.0
CMS2_k127_1526430_43 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000002409 151.0
CMS2_k127_1526430_44 MafB19-like deaminase - - - 0.0000000000000000000000000002409 120.0
CMS2_k127_1526430_45 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000004554 109.0
CMS2_k127_1526430_46 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000005396 106.0
CMS2_k127_1526430_47 PFAM TrkA-N domain K10716 - - 0.0000000000000000000175 94.0
CMS2_k127_1526430_48 STAS domain K04749 - - 0.00000000000000000002365 94.0
CMS2_k127_1526430_49 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.0000000001243 62.0
CMS2_k127_1526430_5 Tripartite tricarboxylate transporter TctA family - - - 4.466e-218 687.0
CMS2_k127_1526430_50 Protein conserved in bacteria K07793 - - 0.0000001649 59.0
CMS2_k127_1526430_6 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 608.0
CMS2_k127_1526430_7 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 609.0
CMS2_k127_1526430_8 Glutathione S-Transferase K07393 - 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 484.0
CMS2_k127_1526430_9 PFAM aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 481.0
CMS2_k127_1533382_0 DALR_2 K01883 - 6.1.1.16 3.214e-223 694.0
CMS2_k127_1533382_1 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000001031 180.0
CMS2_k127_1544502_0 AcrB/AcrD/AcrF family - - - 9.966e-317 1003.0
CMS2_k127_1544502_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.835e-292 906.0
CMS2_k127_1544502_10 ROK family K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 334.0
CMS2_k127_1544502_11 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000129 275.0
CMS2_k127_1544502_12 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004798 259.0
CMS2_k127_1544502_13 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003539 256.0
CMS2_k127_1544502_14 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004414 252.0
CMS2_k127_1544502_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006209 253.0
CMS2_k127_1544502_16 Pyroglutamyl peptidase K01304 - 3.4.19.3 0.0000000000000000000000000000000000000000000000000000000000000003758 225.0
CMS2_k127_1544502_17 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000004613 228.0
CMS2_k127_1544502_18 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000002725 216.0
CMS2_k127_1544502_19 alcohol dehydrogenase K08322 - 1.1.1.380 0.0000000000000000000000000000000000000000000000000000000004869 214.0
CMS2_k127_1544502_2 ABC transporter - - - 1.495e-289 897.0
CMS2_k127_1544502_20 Belongs to the TPP enzyme family - - - 0.0000000000000000000000000000006081 129.0
CMS2_k127_1544502_21 O-methyltransferase - - - 0.000000000000000000000000004216 119.0
CMS2_k127_1544502_22 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.0000000000000000000001724 103.0
CMS2_k127_1544502_23 PFAM Carboxymuconolactone decarboxylase - - - 0.000000004731 65.0
CMS2_k127_1544502_24 PFAM Carboxymuconolactone decarboxylase - - - 0.000000006279 61.0
CMS2_k127_1544502_25 redox protein, regulator of disulfide bond formation - - - 0.000006107 49.0
CMS2_k127_1544502_26 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00002795 50.0
CMS2_k127_1544502_27 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00009113 54.0
CMS2_k127_1544502_3 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 9.001e-267 830.0
CMS2_k127_1544502_4 Belongs to the TPP enzyme family K01576 - 4.1.1.7 4.791e-203 646.0
CMS2_k127_1544502_5 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 608.0
CMS2_k127_1544502_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 485.0
CMS2_k127_1544502_7 PFAM NnrS family protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 381.0
CMS2_k127_1544502_8 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 379.0
CMS2_k127_1544502_9 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 342.0
CMS2_k127_1578209_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1307.0
CMS2_k127_1578209_1 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 2.208e-275 856.0
CMS2_k127_1578209_10 TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 539.0
CMS2_k127_1578209_11 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 509.0
CMS2_k127_1578209_12 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 473.0
CMS2_k127_1578209_13 Fe-S type, tartrate fumarate subfamily, alpha subunit K03779 - 4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 459.0
CMS2_k127_1578209_14 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 406.0
CMS2_k127_1578209_15 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 405.0
CMS2_k127_1578209_16 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 403.0
CMS2_k127_1578209_17 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 404.0
CMS2_k127_1578209_18 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 384.0
CMS2_k127_1578209_19 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 369.0
CMS2_k127_1578209_2 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 1.864e-213 668.0
CMS2_k127_1578209_20 cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 375.0
CMS2_k127_1578209_21 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 368.0
CMS2_k127_1578209_22 Belongs to the LDH2 MDH2 oxidoreductase family K16844 - 1.1.1.338 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 367.0
CMS2_k127_1578209_23 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 354.0
CMS2_k127_1578209_24 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 343.0
CMS2_k127_1578209_25 Peptidase family M23 K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 340.0
CMS2_k127_1578209_26 Nitroreductase family K19286 - 1.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 332.0
CMS2_k127_1578209_27 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 329.0
CMS2_k127_1578209_28 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 326.0
CMS2_k127_1578209_29 Fumarase C-terminus K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 318.0
CMS2_k127_1578209_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.347e-213 670.0
CMS2_k127_1578209_30 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 319.0
CMS2_k127_1578209_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002849 276.0
CMS2_k127_1578209_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002219 271.0
CMS2_k127_1578209_33 Ankyrin repeats (3 copies) K06867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005116 273.0
CMS2_k127_1578209_34 PFAM Nitrile hydratase alpha K01721,K20762 - 3.5.5.8,4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000008783 254.0
CMS2_k127_1578209_35 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000003901 234.0
CMS2_k127_1578209_36 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000003272 214.0
CMS2_k127_1578209_37 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000001055 195.0
CMS2_k127_1578209_38 phosphosulfolactate synthase activity K08097 - 4.4.1.19 0.000000000000000000000000000000000000000000000000002776 192.0
CMS2_k127_1578209_39 Acyl-CoA dehydrogenase, N-terminal domain K00248,K00249 - 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000004762 194.0
CMS2_k127_1578209_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 3.966e-212 664.0
CMS2_k127_1578209_40 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000003835 184.0
CMS2_k127_1578209_41 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000008271 174.0
CMS2_k127_1578209_42 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000003223 179.0
CMS2_k127_1578209_43 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000000000000000000000000000000001446 153.0
CMS2_k127_1578209_44 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000000008456 151.0
CMS2_k127_1578209_45 HupE / UreJ protein K03192 - - 0.0000000000000000000000000000000000003934 148.0
CMS2_k127_1578209_46 altronate dehydratase K16845 - 4.4.1.24 0.0000000000000000000000000000000000005091 142.0
CMS2_k127_1578209_47 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.0000000000000000000000000000000000213 139.0
CMS2_k127_1578209_48 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.00000000000000000000000000000002704 128.0
CMS2_k127_1578209_49 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000001682 125.0
CMS2_k127_1578209_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 3.388e-207 653.0
CMS2_k127_1578209_50 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000000000001826 98.0
CMS2_k127_1578209_51 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.0000000000000001194 86.0
CMS2_k127_1578209_52 Protein conserved in bacteria K09914 - - 0.000000000004207 72.0
CMS2_k127_1578209_54 - - - - 0.0000004498 53.0
CMS2_k127_1578209_56 Protein of unknown function (DUF721) - - - 0.00003237 53.0
CMS2_k127_1578209_57 AraC-like ligand binding domain - - - 0.0003758 51.0
CMS2_k127_1578209_6 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 625.0
CMS2_k127_1578209_7 PFAM type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 597.0
CMS2_k127_1578209_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 560.0
CMS2_k127_1578209_9 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 557.0
CMS2_k127_1756270_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 1.143e-262 841.0
CMS2_k127_1756270_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K03852 - 2.3.3.15 5.953e-259 810.0
CMS2_k127_1756270_10 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 387.0
CMS2_k127_1756270_11 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 372.0
CMS2_k127_1756270_12 Von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 355.0
CMS2_k127_1756270_13 helix_turn _helix lactose operon repressor K02529,K06145 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 333.0
CMS2_k127_1756270_14 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 317.0
CMS2_k127_1756270_15 peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 316.0
CMS2_k127_1756270_16 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 296.0
CMS2_k127_1756270_17 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 304.0
CMS2_k127_1756270_18 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 286.0
CMS2_k127_1756270_19 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001646 286.0
CMS2_k127_1756270_2 argininosuccinate lyase K01755 - 4.3.2.1 3.079e-215 676.0
CMS2_k127_1756270_20 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008369 284.0
CMS2_k127_1756270_21 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006662 281.0
CMS2_k127_1756270_22 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001116 256.0
CMS2_k127_1756270_23 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004043 255.0
CMS2_k127_1756270_24 - - - - 0.0000000000000000000000000000000000000000000000000001931 195.0
CMS2_k127_1756270_25 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000001442 171.0
CMS2_k127_1756270_26 Histidine kinase - - - 0.0000000000000000000000000000000000000000005524 173.0
CMS2_k127_1756270_27 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000006705 167.0
CMS2_k127_1756270_28 - - - - 0.0000000000000000000000000000000000000001058 156.0
CMS2_k127_1756270_29 Cupin 2, conserved barrel domain protein K21700 - - 0.0000000000000000000025 100.0
CMS2_k127_1756270_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 561.0
CMS2_k127_1756270_30 Histidine kinase - - - 0.0000000000001059 83.0
CMS2_k127_1756270_31 - - - - 0.00000005794 53.0
CMS2_k127_1756270_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 559.0
CMS2_k127_1756270_5 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 526.0
CMS2_k127_1756270_6 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 507.0
CMS2_k127_1756270_7 L-carnitine dehydratase bile acid-inducible protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 469.0
CMS2_k127_1756270_8 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 456.0
CMS2_k127_1756270_9 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 390.0
CMS2_k127_1780660_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 0.0 1288.0
CMS2_k127_1780660_1 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 7.5e-322 1007.0
CMS2_k127_1780660_10 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000000001854 210.0
CMS2_k127_1780660_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001518 215.0
CMS2_k127_1780660_12 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000003379 207.0
CMS2_k127_1780660_13 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000004 197.0
CMS2_k127_1780660_14 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000001712 141.0
CMS2_k127_1780660_15 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000001549 127.0
CMS2_k127_1780660_16 Protein of unknown function (DUF2846) - - - 0.0000000000001562 77.0
CMS2_k127_1780660_17 Protein of unknown function (DUF2846) - - - 0.000000008913 62.0
CMS2_k127_1780660_18 Protein of unknown function (DUF2846) - - - 0.000004044 55.0
CMS2_k127_1780660_19 Protein of unknown function (DUF2846) - - - 0.0003772 49.0
CMS2_k127_1780660_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 7.195e-242 753.0
CMS2_k127_1780660_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 7.385e-212 675.0
CMS2_k127_1780660_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 528.0
CMS2_k127_1780660_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 443.0
CMS2_k127_1780660_6 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 343.0
CMS2_k127_1780660_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 325.0
CMS2_k127_1780660_8 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 320.0
CMS2_k127_1780660_9 C4-dicarboxylate ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002154 266.0
CMS2_k127_1814564_0 PFAM Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 402.0
CMS2_k127_1814564_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 293.0
CMS2_k127_1814564_2 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001247 271.0
CMS2_k127_1814564_3 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002265 261.0
CMS2_k127_1814564_4 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000002738 233.0
CMS2_k127_1814564_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000001281 218.0
CMS2_k127_1814564_6 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000002789 182.0
CMS2_k127_1814564_7 MerR, DNA binding - - - 0.00000000000000000000000000000003977 134.0
CMS2_k127_1815708_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 6.222e-302 934.0
CMS2_k127_1815708_1 AAA domain - - - 2.415e-294 923.0
CMS2_k127_1815708_10 Sulfate permease family K03321 - - 1.594e-222 705.0
CMS2_k127_1815708_11 COG0471 Di- and tricarboxylate transporters - - - 5.878e-218 693.0
CMS2_k127_1815708_12 4Fe-4S single cluster domain - - - 1.031e-213 668.0
CMS2_k127_1815708_13 B12 binding domain - - - 1.29e-213 681.0
CMS2_k127_1815708_14 cytochrome d1, heme region K19345 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 560.0
CMS2_k127_1815708_15 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 560.0
CMS2_k127_1815708_16 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009933 536.0
CMS2_k127_1815708_17 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 539.0
CMS2_k127_1815708_18 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 524.0
CMS2_k127_1815708_19 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 505.0
CMS2_k127_1815708_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.139e-260 815.0
CMS2_k127_1815708_20 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 486.0
CMS2_k127_1815708_21 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 439.0
CMS2_k127_1815708_22 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 430.0
CMS2_k127_1815708_23 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 423.0
CMS2_k127_1815708_24 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 411.0
CMS2_k127_1815708_25 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 390.0
CMS2_k127_1815708_26 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 367.0
CMS2_k127_1815708_27 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 359.0
CMS2_k127_1815708_28 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 344.0
CMS2_k127_1815708_29 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 340.0
CMS2_k127_1815708_3 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 2.837e-254 795.0
CMS2_k127_1815708_30 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 325.0
CMS2_k127_1815708_31 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 312.0
CMS2_k127_1815708_32 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 304.0
CMS2_k127_1815708_33 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 289.0
CMS2_k127_1815708_34 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 287.0
CMS2_k127_1815708_35 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006679 277.0
CMS2_k127_1815708_36 Pfam Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001043 273.0
CMS2_k127_1815708_37 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001049 263.0
CMS2_k127_1815708_38 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004383 263.0
CMS2_k127_1815708_39 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001882 258.0
CMS2_k127_1815708_4 Cytochrome b(N-terminal)/b6/petB - - - 1.087e-251 792.0
CMS2_k127_1815708_40 Dienelactone hydrolase family K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002178 257.0
CMS2_k127_1815708_41 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001698 248.0
CMS2_k127_1815708_42 Regulator K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004711 249.0
CMS2_k127_1815708_43 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003306 249.0
CMS2_k127_1815708_44 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000000000000001342 240.0
CMS2_k127_1815708_45 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000002017 239.0
CMS2_k127_1815708_46 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000001023 231.0
CMS2_k127_1815708_47 Nicotinamidase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000001682 232.0
CMS2_k127_1815708_48 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000007617 243.0
CMS2_k127_1815708_49 transcriptional regulator AsnC family - - - 0.0000000000000000000000000000000000000000000000000000000000000003599 225.0
CMS2_k127_1815708_5 DNA polymerase X family K02347 - - 5.418e-251 785.0
CMS2_k127_1815708_50 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000008472 215.0
CMS2_k127_1815708_51 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000001376 226.0
CMS2_k127_1815708_52 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000507 204.0
CMS2_k127_1815708_53 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000003266 199.0
CMS2_k127_1815708_54 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000005403 198.0
CMS2_k127_1815708_55 Domain of unknown function (DUF4202) - - - 0.0000000000000000000000000000000000000000000000000001511 194.0
CMS2_k127_1815708_56 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000000000000000008187 181.0
CMS2_k127_1815708_57 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000001357 168.0
CMS2_k127_1815708_58 - - - - 0.000000000000000000000000000000000000000002251 169.0
CMS2_k127_1815708_59 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000000000000009919 153.0
CMS2_k127_1815708_6 cation transport ATPase K01533 - 3.6.3.4 1.811e-249 796.0
CMS2_k127_1815708_60 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.00000000000000000000000000000000000008333 144.0
CMS2_k127_1815708_61 - - - - 0.00000000000000000000000000000000003153 143.0
CMS2_k127_1815708_62 PFAM Invasion gene expression up-regulator, SirB - - - 0.00000000000000000000000000000000003216 139.0
CMS2_k127_1815708_63 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000002652 132.0
CMS2_k127_1815708_64 Anti-sigma-K factor rskA - - - 0.0000000000000000000000000000001556 134.0
CMS2_k127_1815708_65 Universal stress protein - - - 0.0000000000000000000000000000003408 128.0
CMS2_k127_1815708_66 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000003729 126.0
CMS2_k127_1815708_67 Cytochrome c - - - 0.000000000000000000000000000006309 123.0
CMS2_k127_1815708_68 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000000000009084 122.0
CMS2_k127_1815708_69 PFAM UspA - - - 0.0000000000000000000000000000125 130.0
CMS2_k127_1815708_7 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 4.809e-247 769.0
CMS2_k127_1815708_70 Cytochrome c - - - 0.000000000000000000000000000077 120.0
CMS2_k127_1815708_71 Cytochrome c K08738 - - 0.0000000000000000000000000003684 117.0
CMS2_k127_1815708_72 Universal stress protein - - - 0.00000000000000000000000003674 113.0
CMS2_k127_1815708_73 protein required for cytochrome oxidase assembly K02259 - - 0.000000000000000000002383 106.0
CMS2_k127_1815708_74 Protein of unknown function (DUF1161) - - - 0.00000000000000000002906 93.0
CMS2_k127_1815708_75 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000005849 93.0
CMS2_k127_1815708_76 Pfam Response regulator receiver - - - 0.000000000000000000108 94.0
CMS2_k127_1815708_77 Protein required for attachment to host cells - - - 0.000000000000000001826 93.0
CMS2_k127_1815708_78 - - - - 0.000000000000001059 79.0
CMS2_k127_1815708_79 Cytochrome oxidase maturation protein cbb3-type - - - 0.00000000000002739 84.0
CMS2_k127_1815708_8 Poly-beta-hydroxybutyrate polymerase K03821 - - 5.183e-246 772.0
CMS2_k127_1815708_80 Bacterial SH3 domain - - - 0.0000000000004617 76.0
CMS2_k127_1815708_81 - - - - 0.00000000000269 69.0
CMS2_k127_1815708_82 redox protein, regulator of disulfide bond formation - - - 0.00000000005904 68.0
CMS2_k127_1815708_9 Cytochrome D1 heme domain - - - 6.712e-238 745.0
CMS2_k127_192285_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1082.0
CMS2_k127_192285_1 Uncharacterized protein family (UPF0051) K09014 - - 1.571e-238 744.0
CMS2_k127_192285_10 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 426.0
CMS2_k127_192285_11 (Lipo)protein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 424.0
CMS2_k127_192285_12 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 415.0
CMS2_k127_192285_13 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 412.0
CMS2_k127_192285_14 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 401.0
CMS2_k127_192285_15 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 389.0
CMS2_k127_192285_16 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 377.0
CMS2_k127_192285_17 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 340.0
CMS2_k127_192285_18 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 336.0
CMS2_k127_192285_19 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 326.0
CMS2_k127_192285_2 Homospermidine synthase K00808 - 2.5.1.44 7.984e-210 662.0
CMS2_k127_192285_20 membrane-bound metal-dependent K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 323.0
CMS2_k127_192285_21 Scaffold protein Nfu/NifU N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001095 275.0
CMS2_k127_192285_22 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001829 278.0
CMS2_k127_192285_23 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002035 260.0
CMS2_k127_192285_24 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000333 249.0
CMS2_k127_192285_25 PFAM Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004965 250.0
CMS2_k127_192285_26 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000000000000000000001135 244.0
CMS2_k127_192285_27 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000008033 228.0
CMS2_k127_192285_28 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000000000004242 227.0
CMS2_k127_192285_29 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000356 219.0
CMS2_k127_192285_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 3.921e-206 651.0
CMS2_k127_192285_30 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000001825 207.0
CMS2_k127_192285_31 alpha/beta hydrolase fold K01253 - 3.3.2.9 0.0000000000000000000000000000000000000000000000000000004994 203.0
CMS2_k127_192285_32 - - - - 0.000000000000000000000000000000000000000000000000000001236 208.0
CMS2_k127_192285_33 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000001455 176.0
CMS2_k127_192285_34 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000001052 162.0
CMS2_k127_192285_35 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.0000000000000000000000000000000000000000005865 160.0
CMS2_k127_192285_36 - - - - 0.00000000000000000000000000000001636 132.0
CMS2_k127_192285_37 - - - - 0.000000000000000000000000000001196 126.0
CMS2_k127_192285_38 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000001365 129.0
CMS2_k127_192285_39 acyl carrier protein K02078 - - 0.000000000000000000000000001573 114.0
CMS2_k127_192285_4 COG1012 NAD-dependent aldehyde dehydrogenases K04072,K13922 - 1.1.1.1,1.2.1.10,1.2.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 575.0
CMS2_k127_192285_40 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.0000000000000000000187 97.0
CMS2_k127_192285_41 dehydratase - - - 0.0000000000000001193 83.0
CMS2_k127_192285_42 membrane - - - 0.00000000000002319 81.0
CMS2_k127_192285_43 Tetratricopeptide repeat - - - 0.000000004479 66.0
CMS2_k127_192285_44 PFAM DsrE family protein K07235 - - 0.00006235 51.0
CMS2_k127_192285_5 MMPL family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 551.0
CMS2_k127_192285_6 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 482.0
CMS2_k127_192285_7 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 477.0
CMS2_k127_192285_8 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 482.0
CMS2_k127_192285_9 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 458.0
CMS2_k127_1998036_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2383.0
CMS2_k127_1998036_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1187.0
CMS2_k127_1998036_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 522.0
CMS2_k127_1998036_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001047 259.0
CMS2_k127_1998036_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000001053 223.0
CMS2_k127_1998036_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000002099 81.0
CMS2_k127_2006393_0 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002348 289.0
CMS2_k127_2006393_1 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005573 275.0
CMS2_k127_2006393_10 Isochorismatase family - - - 0.0000000000001302 81.0
CMS2_k127_2006393_11 PFAM DoxX family protein K15977 - - 0.000002353 55.0
CMS2_k127_2006393_2 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005879 274.0
CMS2_k127_2006393_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000331 263.0
CMS2_k127_2006393_4 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000103 245.0
CMS2_k127_2006393_5 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000319 243.0
CMS2_k127_2006393_6 Peptidase M15 K03791 - - 0.0000000000000000000000000000000000000000000000000000000000000004951 227.0
CMS2_k127_2006393_7 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000004687 157.0
CMS2_k127_2006393_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000006553 128.0
CMS2_k127_2006393_9 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000009259 81.0
CMS2_k127_200987_0 PFAM Aminotransferase, class I K14287 - 2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 487.0
CMS2_k127_200987_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 479.0
CMS2_k127_200987_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 353.0
CMS2_k127_200987_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000004645 141.0
CMS2_k127_200987_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000003381 126.0
CMS2_k127_200987_5 - - - - 0.000000000000000000001098 108.0
CMS2_k127_200987_6 - - - - 0.0000000000001542 73.0
CMS2_k127_2053858_0 Aconitase family (aconitate hydratase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 562.0
CMS2_k127_2053858_1 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 364.0
CMS2_k127_2053858_2 acyl-CoA dehydrogenase K06446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 331.0
CMS2_k127_2053858_3 Enoyl-(Acyl carrier protein) reductase K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 292.0
CMS2_k127_2053858_4 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008838 269.0
CMS2_k127_2053858_5 Belongs to the LeuD family K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000001941 215.0
CMS2_k127_2053858_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000001347 143.0
CMS2_k127_2053858_7 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000004741 114.0
CMS2_k127_2053858_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000006791 113.0
CMS2_k127_2079268_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K22424 - 2.7.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 319.0
CMS2_k127_2079268_1 Glycosyl transferase family 2 K20534 - - 0.0000000000000000001776 91.0
CMS2_k127_21331_0 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 551.0
CMS2_k127_21331_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 419.0
CMS2_k127_21331_10 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000088 152.0
CMS2_k127_21331_11 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000005633 107.0
CMS2_k127_21331_12 Helix-hairpin-helix motif - - - 0.0000000000000000005202 90.0
CMS2_k127_21331_14 Antibiotic biosynthesis monooxygenase - - - 0.00000000001005 73.0
CMS2_k127_21331_15 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000003202 60.0
CMS2_k127_21331_17 PFAM Rhodanese-like domain - - - 0.000000028 61.0
CMS2_k127_21331_18 - - - - 0.0000003835 57.0
CMS2_k127_21331_19 - - - - 0.0000005097 53.0
CMS2_k127_21331_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 305.0
CMS2_k127_21331_20 - - - - 0.00002792 49.0
CMS2_k127_21331_3 Transcriptional regulator K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 303.0
CMS2_k127_21331_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 290.0
CMS2_k127_21331_5 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 291.0
CMS2_k127_21331_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001878 258.0
CMS2_k127_21331_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006044 235.0
CMS2_k127_21331_8 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002819 227.0
CMS2_k127_21331_9 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000007929 197.0
CMS2_k127_2191128_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 8.077e-227 711.0
CMS2_k127_2191128_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 607.0
CMS2_k127_2191128_10 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 331.0
CMS2_k127_2191128_11 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 288.0
CMS2_k127_2191128_12 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003367 278.0
CMS2_k127_2191128_13 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 258.0
CMS2_k127_2191128_14 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001499 255.0
CMS2_k127_2191128_15 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000001012 239.0
CMS2_k127_2191128_16 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002668 243.0
CMS2_k127_2191128_17 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000002025 217.0
CMS2_k127_2191128_18 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000001753 217.0
CMS2_k127_2191128_19 PFAM ApaG domain protein K06195 - - 0.000000000000000000000000000000000000000000000000000000003809 201.0
CMS2_k127_2191128_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 554.0
CMS2_k127_2191128_20 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000000004001 198.0
CMS2_k127_2191128_21 - - - - 0.00000000000000000000000000000000000000000000000000000007509 203.0
CMS2_k127_2191128_22 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000009765 181.0
CMS2_k127_2191128_23 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000000001124 177.0
CMS2_k127_2191128_24 TPM domain - - - 0.00000000000000000000000000000005625 133.0
CMS2_k127_2191128_25 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000001143 123.0
CMS2_k127_2191128_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 476.0
CMS2_k127_2191128_4 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 473.0
CMS2_k127_2191128_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 417.0
CMS2_k127_2191128_6 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 369.0
CMS2_k127_2191128_7 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 351.0
CMS2_k127_2191128_8 TIGRFAM pyridine nucleotide-disulfide oxidoreductase family protein K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 340.0
CMS2_k127_2191128_9 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 331.0
CMS2_k127_2212336_0 CoA-binding domain protein K01905,K22224 - 6.2.1.13 1.375e-230 734.0
CMS2_k127_2212336_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 5.481e-223 701.0
CMS2_k127_2212336_10 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 485.0
CMS2_k127_2212336_11 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 480.0
CMS2_k127_2212336_12 PFAM type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 465.0
CMS2_k127_2212336_13 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 439.0
CMS2_k127_2212336_14 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 431.0
CMS2_k127_2212336_15 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 435.0
CMS2_k127_2212336_16 abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 417.0
CMS2_k127_2212336_17 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 415.0
CMS2_k127_2212336_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 412.0
CMS2_k127_2212336_19 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 396.0
CMS2_k127_2212336_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 5.154e-217 681.0
CMS2_k127_2212336_20 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 394.0
CMS2_k127_2212336_21 Glutathione S-transferase, N-terminal domain K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 362.0
CMS2_k127_2212336_22 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007576 382.0
CMS2_k127_2212336_23 4-phosphoerythronate dehydrogenase activity K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 368.0
CMS2_k127_2212336_24 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 334.0
CMS2_k127_2212336_25 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 331.0
CMS2_k127_2212336_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 332.0
CMS2_k127_2212336_27 major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 329.0
CMS2_k127_2212336_28 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 313.0
CMS2_k127_2212336_29 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 310.0
CMS2_k127_2212336_3 type IV-A pilus assembly ATPase PilB K02652 - - 2.616e-213 676.0
CMS2_k127_2212336_30 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 308.0
CMS2_k127_2212336_31 ATPase activity, coupled to transmembrane movement of substances - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 302.0
CMS2_k127_2212336_32 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 298.0
CMS2_k127_2212336_33 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008236 271.0
CMS2_k127_2212336_34 major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002559 278.0
CMS2_k127_2212336_35 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001097 269.0
CMS2_k127_2212336_36 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000001006 248.0
CMS2_k127_2212336_37 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001694 240.0
CMS2_k127_2212336_38 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.00000000000000000000000000000000000000000000000000000000000002185 229.0
CMS2_k127_2212336_39 - - - - 0.0000000000000000000000000000000000000000000000000000000000002786 220.0
CMS2_k127_2212336_4 Sigma-54 interaction domain - - - 1.372e-209 661.0
CMS2_k127_2212336_40 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000004026 207.0
CMS2_k127_2212336_41 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000008845 208.0
CMS2_k127_2212336_42 - - - - 0.000000000000000000000000000000000000000000000000000000004521 204.0
CMS2_k127_2212336_43 - K01992 - - 0.0000000000000000000000000000000000000000000002223 177.0
CMS2_k127_2212336_44 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000006937 172.0
CMS2_k127_2212336_45 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000005647 172.0
CMS2_k127_2212336_46 stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000001548 155.0
CMS2_k127_2212336_47 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000008266 140.0
CMS2_k127_2212336_48 Psort location Cytoplasmic, score K01523 - 3.6.1.31 0.00000000000000000000000000000000002979 142.0
CMS2_k127_2212336_49 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000007026 136.0
CMS2_k127_2212336_5 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.703e-200 631.0
CMS2_k127_2212336_50 BolA-like protein - - - 0.00000000000000000000000000000004219 127.0
CMS2_k127_2212336_51 - - - - 0.000000000000000000000000000000575 140.0
CMS2_k127_2212336_52 - - - - 0.0000000000000000000000000001238 123.0
CMS2_k127_2212336_53 thiolester hydrolase activity - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000009168 124.0
CMS2_k127_2212336_54 transporter antisigma-factor antagonist STAS K07122 - - 0.00000000000000000000006039 104.0
CMS2_k127_2212336_55 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000007516 96.0
CMS2_k127_2212336_56 Acyl-CoA dehydrogenase, N-terminal domain K00252 - 1.3.8.6 0.000000000000000000004107 94.0
CMS2_k127_2212336_57 Domain of unknown function (DUF4340) - - - 0.0000000000000000004726 101.0
CMS2_k127_2212336_58 Prokaryotic N-terminal methylation motif - - - 0.00000000000000001143 85.0
CMS2_k127_2212336_59 - - - - 0.000001345 58.0
CMS2_k127_2212336_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 604.0
CMS2_k127_2212336_7 Belongs to the TPP enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 546.0
CMS2_k127_2212336_8 Belongs to the peptidase S1C family K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 488.0
CMS2_k127_2212336_9 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 489.0
CMS2_k127_2224239_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 306.0
CMS2_k127_2224239_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003037 255.0
CMS2_k127_2224239_2 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000001603 200.0
CMS2_k127_2224239_3 MerR family transcriptional regulator K08365 - - 0.00000000000000000009381 92.0
CMS2_k127_227943_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 3.641e-212 672.0
CMS2_k127_227943_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 565.0
CMS2_k127_227943_10 Small MutS-related domain - - - 0.00000000000000000000000000000000000000000000000000000004431 200.0
CMS2_k127_227943_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 531.0
CMS2_k127_227943_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 521.0
CMS2_k127_227943_4 Putative metallopeptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 477.0
CMS2_k127_227943_5 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 455.0
CMS2_k127_227943_6 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002202 262.0
CMS2_k127_227943_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000001491 229.0
CMS2_k127_227943_8 xylan catabolic process K09252 - 3.1.1.73 0.000000000000000000000000000000000000000000000000000000000000003728 228.0
CMS2_k127_227943_9 Nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000003738 203.0
CMS2_k127_232665_0 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.0 1797.0
CMS2_k127_232665_1 SMART alpha amylase catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.0 1515.0
CMS2_k127_232665_10 PFAM Glycosyl transferase, family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 590.0
CMS2_k127_232665_11 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 581.0
CMS2_k127_232665_12 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 565.0
CMS2_k127_232665_13 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 523.0
CMS2_k127_232665_14 serine protease K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 478.0
CMS2_k127_232665_15 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 439.0
CMS2_k127_232665_16 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 427.0
CMS2_k127_232665_17 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 418.0
CMS2_k127_232665_18 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 408.0
CMS2_k127_232665_19 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 380.0
CMS2_k127_232665_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1163.0
CMS2_k127_232665_20 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 357.0
CMS2_k127_232665_21 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 351.0
CMS2_k127_232665_22 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 339.0
CMS2_k127_232665_23 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 323.0
CMS2_k127_232665_24 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 300.0
CMS2_k127_232665_25 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 292.0
CMS2_k127_232665_26 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 288.0
CMS2_k127_232665_27 PFAM Conserved TM helix repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 286.0
CMS2_k127_232665_28 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 283.0
CMS2_k127_232665_29 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002391 293.0
CMS2_k127_232665_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.069e-314 973.0
CMS2_k127_232665_30 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001938 269.0
CMS2_k127_232665_31 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007281 257.0
CMS2_k127_232665_32 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000004908 237.0
CMS2_k127_232665_33 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000002508 238.0
CMS2_k127_232665_34 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000009491 231.0
CMS2_k127_232665_35 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000434 224.0
CMS2_k127_232665_36 D-isomer specific 2-hydroxyacid dehydrogenase K00058 GO:0003674,GO:0003824,GO:0004617,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000002577 161.0
CMS2_k127_232665_37 preprotein translocase subunit YajC K03210 - - 0.00000000000000000000000000000000000463 139.0
CMS2_k127_232665_38 Sel1-like repeats. - - - 0.00000000000000000003422 103.0
CMS2_k127_232665_39 Protein of unknown function (DUF3567) - - - 0.0000000000003992 72.0
CMS2_k127_232665_4 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 7.85e-300 939.0
CMS2_k127_232665_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 3.73e-279 870.0
CMS2_k127_232665_6 trehalohydrolase K01236 - 3.2.1.141 5.187e-254 797.0
CMS2_k127_232665_7 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 4.834e-224 704.0
CMS2_k127_232665_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.7e-206 649.0
CMS2_k127_232665_9 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 594.0
CMS2_k127_2426616_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 2.512e-312 974.0
CMS2_k127_2426616_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.554e-286 899.0
CMS2_k127_2426616_10 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 9.846e-197 632.0
CMS2_k127_2426616_11 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 600.0
CMS2_k127_2426616_12 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 599.0
CMS2_k127_2426616_13 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 543.0
CMS2_k127_2426616_14 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 536.0
CMS2_k127_2426616_15 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 524.0
CMS2_k127_2426616_16 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 508.0
CMS2_k127_2426616_17 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 502.0
CMS2_k127_2426616_18 exonuclease of the beta-lactamase fold involved in RNA processing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 502.0
CMS2_k127_2426616_19 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 493.0
CMS2_k127_2426616_2 Belongs to the IlvD Edd family - - - 7.487e-280 869.0
CMS2_k127_2426616_20 Type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 496.0
CMS2_k127_2426616_21 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 484.0
CMS2_k127_2426616_22 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 484.0
CMS2_k127_2426616_23 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 477.0
CMS2_k127_2426616_24 Histidine kinase K10125 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 488.0
CMS2_k127_2426616_25 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 447.0
CMS2_k127_2426616_26 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 430.0
CMS2_k127_2426616_27 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 445.0
CMS2_k127_2426616_28 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 399.0
CMS2_k127_2426616_29 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 387.0
CMS2_k127_2426616_3 Protein of unknown function, DUF255 K06888 - - 4.78e-276 863.0
CMS2_k127_2426616_30 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 367.0
CMS2_k127_2426616_31 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 364.0
CMS2_k127_2426616_32 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 339.0
CMS2_k127_2426616_33 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 319.0
CMS2_k127_2426616_34 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 328.0
CMS2_k127_2426616_35 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000911 273.0
CMS2_k127_2426616_36 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001506 271.0
CMS2_k127_2426616_37 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001263 265.0
CMS2_k127_2426616_38 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000008632 227.0
CMS2_k127_2426616_39 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000002667 227.0
CMS2_k127_2426616_4 type IV pilus secretin PilQ K02666 - - 1.036e-262 826.0
CMS2_k127_2426616_40 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000896 224.0
CMS2_k127_2426616_41 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000002255 225.0
CMS2_k127_2426616_42 PFAM MmgE PrpD - - - 0.0000000000000000000000000000000000000000000000000000000001275 221.0
CMS2_k127_2426616_43 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000001322 203.0
CMS2_k127_2426616_44 - - - - 0.000000000000000000000000000000000000000000000000000002061 198.0
CMS2_k127_2426616_45 fimbrial biogenesis protein PilN K02663 - - 0.00000000000000000000000000000000000000000000000000009694 195.0
CMS2_k127_2426616_46 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000000001885 185.0
CMS2_k127_2426616_47 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000001641 172.0
CMS2_k127_2426616_48 endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000001632 177.0
CMS2_k127_2426616_49 pilus assembly protein PilP K02665 - - 0.000000000000000000000000000000000000000000004745 169.0
CMS2_k127_2426616_5 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 2.666e-261 813.0
CMS2_k127_2426616_50 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.0000000000000000000000000000000000000001709 156.0
CMS2_k127_2426616_51 SapC - - - 0.0000000000000000000000000000000000002582 154.0
CMS2_k127_2426616_52 OmpA-like transmembrane domain - - - 0.00000000000000000000000000000007318 132.0
CMS2_k127_2426616_53 Rubredoxin - - - 0.00000000000000000000000000008613 115.0
CMS2_k127_2426616_54 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000000000003043 115.0
CMS2_k127_2426616_55 TCP-1/cpn60 chaperonin family K04077 - - 0.00000000000000000000005974 98.0
CMS2_k127_2426616_56 - - - - 0.000000000000001992 79.0
CMS2_k127_2426616_6 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 6.545e-238 749.0
CMS2_k127_2426616_7 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 1.06e-206 650.0
CMS2_k127_2426616_8 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 2.02e-200 648.0
CMS2_k127_2426616_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.57e-198 627.0
CMS2_k127_2506966_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1304.0
CMS2_k127_2506966_1 Neisseria PilC beta-propeller domain K02674 - - 3.652e-312 992.0
CMS2_k127_2506966_10 type IV pilus modification protein PilV K02671 - - 0.0000000000000000000000000000000000000006855 155.0
CMS2_k127_2506966_11 Prokaryotic N-terminal methylation motif K02655 - - 0.00000000000000000000001075 109.0
CMS2_k127_2506966_12 Tfp pilus assembly protein - - - 0.0000000000000000000006957 102.0
CMS2_k127_2506966_13 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000002119 53.0
CMS2_k127_2506966_2 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381 - 1.8.1.2 1.425e-264 825.0
CMS2_k127_2506966_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 472.0
CMS2_k127_2506966_4 Bacterial regulatory helix-turn-helix protein, lysR family K13634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 431.0
CMS2_k127_2506966_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 406.0
CMS2_k127_2506966_6 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 309.0
CMS2_k127_2506966_7 conserved protein ucp030820 - - - 0.0000000000000000000000000000000000000000000000000469 184.0
CMS2_k127_2506966_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000002303 180.0
CMS2_k127_2506966_9 Pilus assembly protein PilX - - - 0.0000000000000000000000000000000000000002171 159.0
CMS2_k127_2556420_0 FAD dependent oxidoreductase - - - 1.589e-216 687.0
CMS2_k127_2556420_1 Tripartite tricarboxylate transporter TctA family K07793 - - 5.929e-215 676.0
CMS2_k127_2556420_10 DNA-damage-repair toleration protein DRT102 - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.00008423 52.0
CMS2_k127_2556420_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 462.0
CMS2_k127_2556420_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 331.0
CMS2_k127_2556420_4 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 295.0
CMS2_k127_2556420_5 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 307.0
CMS2_k127_2556420_6 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000031 171.0
CMS2_k127_2556420_7 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000000000000000000000000000003182 135.0
CMS2_k127_2556420_8 Protein of unknown function (DUF3301) - - - 0.0000000000000000000000008695 107.0
CMS2_k127_2639529_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1161.0
CMS2_k127_2639529_1 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 549.0
CMS2_k127_2639529_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000009464 112.0
CMS2_k127_2639529_11 Cupin domain - - - 0.0000000000000001783 92.0
CMS2_k127_2639529_12 transporter component K07112 - - 0.000000236 52.0
CMS2_k127_2639529_13 - - - - 0.00000508 54.0
CMS2_k127_2639529_2 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 451.0
CMS2_k127_2639529_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 343.0
CMS2_k127_2639529_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002046 266.0
CMS2_k127_2639529_5 Protein of unknown function (DUF2799) - - - 0.0000000000000000000000000000000000000000824 158.0
CMS2_k127_2639529_6 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000001115 132.0
CMS2_k127_2639529_8 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000004672 134.0
CMS2_k127_2639529_9 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000004776 123.0
CMS2_k127_2648225_0 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 599.0
CMS2_k127_2648225_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 555.0
CMS2_k127_2648225_10 PilZ domain - - - 0.0006281 49.0
CMS2_k127_2648225_2 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007754 265.0
CMS2_k127_2648225_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000003887 243.0
CMS2_k127_2648225_4 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000000000001846 215.0
CMS2_k127_2648225_5 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000001132 192.0
CMS2_k127_2648225_6 - - - - 0.00000000000000000000000000000000000000000000001512 182.0
CMS2_k127_2648225_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000002655 177.0
CMS2_k127_2648225_8 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000002331 145.0
CMS2_k127_2648225_9 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000001213 147.0
CMS2_k127_2678773_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 338.0
CMS2_k127_2678773_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 311.0
CMS2_k127_2678773_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000002633 241.0
CMS2_k127_2678773_3 UPF0761 membrane protein K07058 - - 0.000000000000000000000000003764 115.0
CMS2_k127_2700564_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 574.0
CMS2_k127_2700564_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 383.0
CMS2_k127_2700564_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000006004 190.0
CMS2_k127_2700564_3 Iron-binding zinc finger CDGSH type K05710 - - 0.00000000000003894 85.0
CMS2_k127_2700564_4 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000007273 80.0
CMS2_k127_2700564_5 PFAM aldo keto reductase - - - 0.00000005334 55.0
CMS2_k127_2700564_6 - - - - 0.0009819 49.0
CMS2_k127_2736884_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1475.0
CMS2_k127_2736884_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.039e-320 994.0
CMS2_k127_2736884_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.988e-208 658.0
CMS2_k127_2736884_11 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.787e-197 626.0
CMS2_k127_2736884_12 synthetase, class II (G H P K01892 - 6.1.1.21 5.917e-196 620.0
CMS2_k127_2736884_13 GcpE protein K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 612.0
CMS2_k127_2736884_14 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 603.0
CMS2_k127_2736884_15 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 584.0
CMS2_k127_2736884_16 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 594.0
CMS2_k127_2736884_17 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 544.0
CMS2_k127_2736884_18 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 534.0
CMS2_k127_2736884_19 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 522.0
CMS2_k127_2736884_2 Belongs to the UbiD family K03182 - 4.1.1.98 8.936e-250 781.0
CMS2_k127_2736884_20 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 520.0
CMS2_k127_2736884_21 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 503.0
CMS2_k127_2736884_22 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 487.0
CMS2_k127_2736884_23 PFAM Isocitrate isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 485.0
CMS2_k127_2736884_24 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 477.0
CMS2_k127_2736884_25 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 466.0
CMS2_k127_2736884_26 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 467.0
CMS2_k127_2736884_27 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 454.0
CMS2_k127_2736884_28 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 426.0
CMS2_k127_2736884_29 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 422.0
CMS2_k127_2736884_3 Large family of predicted nucleotide-binding domains K07175 - - 7.314e-244 760.0
CMS2_k127_2736884_30 Rhodanese Homology Domain K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 422.0
CMS2_k127_2736884_31 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 417.0
CMS2_k127_2736884_32 4Fe-4S ferredoxin, iron-sulfur binding K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 407.0
CMS2_k127_2736884_33 Hemolysin activation secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 425.0
CMS2_k127_2736884_34 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 395.0
CMS2_k127_2736884_35 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 397.0
CMS2_k127_2736884_36 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 389.0
CMS2_k127_2736884_37 COG2998 ABC-type tungstate transport system, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 378.0
CMS2_k127_2736884_38 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 336.0
CMS2_k127_2736884_39 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 326.0
CMS2_k127_2736884_4 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 4.781e-243 759.0
CMS2_k127_2736884_40 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 325.0
CMS2_k127_2736884_41 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 320.0
CMS2_k127_2736884_42 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 317.0
CMS2_k127_2736884_43 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 320.0
CMS2_k127_2736884_44 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 306.0
CMS2_k127_2736884_45 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 306.0
CMS2_k127_2736884_46 ABC-type molybdate transport system, permease component K02018 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 297.0
CMS2_k127_2736884_47 ABC transporter K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 290.0
CMS2_k127_2736884_48 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 294.0
CMS2_k127_2736884_49 belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000607 291.0
CMS2_k127_2736884_5 FtsX-like permease family K02004 - - 1.297e-242 777.0
CMS2_k127_2736884_50 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001831 271.0
CMS2_k127_2736884_51 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009116 263.0
CMS2_k127_2736884_52 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000001245 256.0
CMS2_k127_2736884_53 PFAM Alkyl hydroperoxide reductase K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000003936 249.0
CMS2_k127_2736884_54 Domain of unknown function (DUF1932) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001581 254.0
CMS2_k127_2736884_55 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000002704 243.0
CMS2_k127_2736884_56 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005703 245.0
CMS2_k127_2736884_57 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - 0.000000000000000000000000000000000000000000000000000000000000000004195 234.0
CMS2_k127_2736884_58 PFAM molybdopterin biosynthesis MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000004877 228.0
CMS2_k127_2736884_59 Type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000000000000000000000000000003799 233.0
CMS2_k127_2736884_6 4Fe-4S dicluster domain - - - 6.419e-241 764.0
CMS2_k127_2736884_60 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000000000005329 226.0
CMS2_k127_2736884_61 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000002444 235.0
CMS2_k127_2736884_62 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000003627 229.0
CMS2_k127_2736884_63 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000009017 229.0
CMS2_k127_2736884_64 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000000003104 213.0
CMS2_k127_2736884_65 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000009735 212.0
CMS2_k127_2736884_66 PBP superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000006076 218.0
CMS2_k127_2736884_67 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000246 204.0
CMS2_k127_2736884_68 ATP synthase K02115 - - 0.00000000000000000000000000000000000000000000000000000009048 205.0
CMS2_k127_2736884_69 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000001039 200.0
CMS2_k127_2736884_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.484e-228 715.0
CMS2_k127_2736884_70 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000001158 203.0
CMS2_k127_2736884_71 Transcriptional regulator K15539 - - 0.00000000000000000000000000000000000000000004475 172.0
CMS2_k127_2736884_73 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000004037 159.0
CMS2_k127_2736884_74 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000001231 145.0
CMS2_k127_2736884_75 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000003875 148.0
CMS2_k127_2736884_76 Thioesterase - - - 0.0000000000000000000000000000000000000625 149.0
CMS2_k127_2736884_77 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000002335 136.0
CMS2_k127_2736884_78 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000006974 136.0
CMS2_k127_2736884_79 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000000005084 134.0
CMS2_k127_2736884_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 7.598e-224 699.0
CMS2_k127_2736884_80 cytoplasmic chaperone TorD family protein - - - 0.00000000000000000000000000000006412 132.0
CMS2_k127_2736884_81 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000004045 124.0
CMS2_k127_2736884_82 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000005393 122.0
CMS2_k127_2736884_83 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000000000000000000000000007615 115.0
CMS2_k127_2736884_84 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000003767 101.0
CMS2_k127_2736884_85 Protein of unknown function (DUF3306) - - - 0.000000000000000000006657 99.0
CMS2_k127_2736884_86 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000000004616 96.0
CMS2_k127_2736884_87 protein conserved in bacteria K09937 - - 0.00000000000000000195 86.0
CMS2_k127_2736884_88 - - - - 0.00000000000001022 82.0
CMS2_k127_2736884_89 - - - - 0.000002107 52.0
CMS2_k127_2736884_9 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.219e-214 680.0
CMS2_k127_2736884_90 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000003196 50.0
CMS2_k127_2736884_91 COG NOG19114 non supervised orthologous group - - - 0.0000264 51.0
CMS2_k127_2736884_92 PFAM Resolvase, N-terminal - - - 0.00003087 48.0
CMS2_k127_2777606_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1232.0
CMS2_k127_2777606_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1215.0
CMS2_k127_2777606_10 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 417.0
CMS2_k127_2777606_11 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 391.0
CMS2_k127_2777606_12 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 384.0
CMS2_k127_2777606_13 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 381.0
CMS2_k127_2777606_14 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 364.0
CMS2_k127_2777606_15 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 364.0
CMS2_k127_2777606_16 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 345.0
CMS2_k127_2777606_17 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 291.0
CMS2_k127_2777606_18 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 291.0
CMS2_k127_2777606_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002037 295.0
CMS2_k127_2777606_2 UvrD REP K03657 - 3.6.4.12 8.436e-315 979.0
CMS2_k127_2777606_20 PFAM regulatory protein TetR K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002847 277.0
CMS2_k127_2777606_21 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008527 271.0
CMS2_k127_2777606_22 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003434 255.0
CMS2_k127_2777606_23 membrane K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000001111 253.0
CMS2_k127_2777606_24 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000004909 242.0
CMS2_k127_2777606_25 Virulence factor membrane-bound polymerase, C-terminal - - - 0.000000000000000000000000000000000000000000000001251 185.0
CMS2_k127_2777606_26 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000001684 180.0
CMS2_k127_2777606_27 cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000193 179.0
CMS2_k127_2777606_28 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000009739 169.0
CMS2_k127_2777606_29 Virulence factor membrane-bound polymerase, C-terminal - - - 0.000000000000000000000000000000000000000000001211 178.0
CMS2_k127_2777606_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.642e-264 826.0
CMS2_k127_2777606_30 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000001711 166.0
CMS2_k127_2777606_31 sulfur oxidation protein (SoxY) K17226 - - 0.00000000000000000000000000000000000000000000726 170.0
CMS2_k127_2777606_32 - - - - 0.0000000000000000000000000000000000000000001019 169.0
CMS2_k127_2777606_33 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000001458 164.0
CMS2_k127_2777606_34 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000000628 147.0
CMS2_k127_2777606_35 Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000001481 137.0
CMS2_k127_2777606_36 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000007242 139.0
CMS2_k127_2777606_37 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000000000003811 129.0
CMS2_k127_2777606_38 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000004859 126.0
CMS2_k127_2777606_39 Rhodanese Homology Domain - - - 0.000000000000000000000000000001347 126.0
CMS2_k127_2777606_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.537e-229 720.0
CMS2_k127_2777606_40 Protein of unknown function (DUF493) K09158 - - 0.000000000000000000000000000004316 121.0
CMS2_k127_2777606_41 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000008978 113.0
CMS2_k127_2777606_42 peroxiredoxin activity - - - 0.0000000000000000000003416 99.0
CMS2_k127_2777606_43 peroxiredoxin activity - - - 0.000009705 49.0
CMS2_k127_2777606_5 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 1.562e-199 628.0
CMS2_k127_2777606_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.979e-198 629.0
CMS2_k127_2777606_7 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 489.0
CMS2_k127_2777606_8 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 472.0
CMS2_k127_2777606_9 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 465.0
CMS2_k127_2789651_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 466.0
CMS2_k127_2789651_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 453.0
CMS2_k127_2789651_10 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000003415 101.0
CMS2_k127_2789651_2 glycosyl transferase family 8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 364.0
CMS2_k127_2789651_3 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 376.0
CMS2_k127_2789651_4 tpr domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 340.0
CMS2_k127_2789651_5 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 346.0
CMS2_k127_2789651_6 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 343.0
CMS2_k127_2789651_7 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 312.0
CMS2_k127_2789651_8 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000141 219.0
CMS2_k127_2789651_9 Macrocin-O-methyltransferase (TylF) - - - 0.0000000000000000000000000000000000000000000000000000000000008016 218.0
CMS2_k127_2821571_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 368.0
CMS2_k127_2821571_1 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 297.0
CMS2_k127_2821571_2 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000272 199.0
CMS2_k127_2825003_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1075.0
CMS2_k127_2825003_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 562.0
CMS2_k127_2825003_10 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000000000000000000000000000000000000000004713 184.0
CMS2_k127_2825003_11 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000006585 184.0
CMS2_k127_2825003_12 ATP hydrolysis coupled proton transport - - - 0.00000000000000000000000000000000000000000001706 184.0
CMS2_k127_2825003_13 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000001806 166.0
CMS2_k127_2825003_14 FecR protein - - - 0.0000000000000000000000000000000000002097 147.0
CMS2_k127_2825003_15 STAS domain K06378 - - 0.00000000000000000000000001087 115.0
CMS2_k127_2825003_16 Histidine kinase-like ATPase domain - - - 0.00000000000000000001465 96.0
CMS2_k127_2825003_17 Rhodanese Homology Domain - - - 0.0000000000000001028 79.0
CMS2_k127_2825003_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 541.0
CMS2_k127_2825003_3 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 496.0
CMS2_k127_2825003_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 428.0
CMS2_k127_2825003_5 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 409.0
CMS2_k127_2825003_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 389.0
CMS2_k127_2825003_7 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 392.0
CMS2_k127_2825003_8 abc transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 330.0
CMS2_k127_2825003_9 protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 293.0
CMS2_k127_2900098_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 2943.0
CMS2_k127_2900098_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1027.0
CMS2_k127_2900098_10 dihydroorotase K01465 - 3.5.2.3 1.148e-206 651.0
CMS2_k127_2900098_11 transglycosylase K08309 - - 8.433e-206 658.0
CMS2_k127_2900098_12 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 590.0
CMS2_k127_2900098_13 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 588.0
CMS2_k127_2900098_14 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 578.0
CMS2_k127_2900098_15 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 578.0
CMS2_k127_2900098_16 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 512.0
CMS2_k127_2900098_17 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 413.0
CMS2_k127_2900098_18 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 402.0
CMS2_k127_2900098_19 CHAD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 392.0
CMS2_k127_2900098_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.225e-321 997.0
CMS2_k127_2900098_20 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 370.0
CMS2_k127_2900098_21 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 329.0
CMS2_k127_2900098_22 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 319.0
CMS2_k127_2900098_23 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 314.0
CMS2_k127_2900098_24 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 310.0
CMS2_k127_2900098_25 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004639 274.0
CMS2_k127_2900098_26 RNA methyltransferase K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000001635 239.0
CMS2_k127_2900098_27 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002843 229.0
CMS2_k127_2900098_28 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000001455 207.0
CMS2_k127_2900098_29 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000000000000000006569 181.0
CMS2_k127_2900098_3 Putative diguanylate phosphodiesterase - - - 1.485e-281 898.0
CMS2_k127_2900098_30 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000252 154.0
CMS2_k127_2900098_31 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000009381 155.0
CMS2_k127_2900098_32 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000000000001385 136.0
CMS2_k127_2900098_33 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000000000005864 133.0
CMS2_k127_2900098_34 - - - - 0.000000000000002138 80.0
CMS2_k127_2900098_4 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 5.914e-250 779.0
CMS2_k127_2900098_5 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 3.544e-248 771.0
CMS2_k127_2900098_6 polyphosphate kinase - - - 5.22e-219 690.0
CMS2_k127_2900098_7 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 5.909e-214 683.0
CMS2_k127_2900098_8 TrkA-N domain protein K03499 - - 7.579e-212 667.0
CMS2_k127_2900098_9 PFAM DNA photolyase FAD-binding K01669 - 4.1.99.3 4.322e-210 665.0
CMS2_k127_2950317_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1305.0
CMS2_k127_2950317_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.255e-308 951.0
CMS2_k127_2950317_10 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 483.0
CMS2_k127_2950317_11 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 468.0
CMS2_k127_2950317_12 Prephenate dehydratase K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 445.0
CMS2_k127_2950317_13 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 418.0
CMS2_k127_2950317_14 Bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 399.0
CMS2_k127_2950317_15 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 359.0
CMS2_k127_2950317_16 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 302.0
CMS2_k127_2950317_17 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 296.0
CMS2_k127_2950317_18 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000002099 259.0
CMS2_k127_2950317_19 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004803 257.0
CMS2_k127_2950317_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 600.0
CMS2_k127_2950317_20 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000003692 254.0
CMS2_k127_2950317_21 Protein of unknown function (DUF1318) K09978 - - 0.0000000000000000000000000000000000000000000000000001162 192.0
CMS2_k127_2950317_22 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000000004009 170.0
CMS2_k127_2950317_23 Belongs to the ompA family K03286 - - 0.000000000000000000000000000001005 130.0
CMS2_k127_2950317_24 Lipopolysaccharide assembly protein A domain K08992 - - 0.0000000000000000003222 91.0
CMS2_k127_2950317_25 - - - - 0.000000000001533 73.0
CMS2_k127_2950317_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 585.0
CMS2_k127_2950317_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 578.0
CMS2_k127_2950317_5 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 564.0
CMS2_k127_2950317_6 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 546.0
CMS2_k127_2950317_7 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 528.0
CMS2_k127_2950317_8 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 522.0
CMS2_k127_2950317_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 488.0
CMS2_k127_2952353_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 596.0
CMS2_k127_2952353_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 550.0
CMS2_k127_2952353_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000007804 171.0
CMS2_k127_2952353_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 545.0
CMS2_k127_2952353_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 506.0
CMS2_k127_2952353_4 Uncharacterized protein family UPF0004 K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 489.0
CMS2_k127_2952353_5 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 462.0
CMS2_k127_2952353_6 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 401.0
CMS2_k127_2952353_7 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 306.0
CMS2_k127_2952353_8 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003431 261.0
CMS2_k127_2952353_9 TIGRFAM histidinol-phosphate phosphatase family protein K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000395 263.0
CMS2_k127_3027758_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1010.0
CMS2_k127_3027758_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 2.388e-273 861.0
CMS2_k127_3027758_10 Carbon-nitrogen hydrolase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 295.0
CMS2_k127_3027758_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000004666 271.0
CMS2_k127_3027758_12 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002319 258.0
CMS2_k127_3027758_13 peptidase K06194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001271 259.0
CMS2_k127_3027758_14 Conserved TM helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000222 241.0
CMS2_k127_3027758_15 2-keto-4-pentenoate hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000005375 235.0
CMS2_k127_3027758_16 PFAM Formylglycine-generating sulfatase enzyme K18912,K20333 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000005406 206.0
CMS2_k127_3027758_17 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000001127 185.0
CMS2_k127_3027758_18 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000000001627 186.0
CMS2_k127_3027758_19 PFAM regulatory protein, MerR - - - 0.000000000000000000000000000000000000000000000005394 174.0
CMS2_k127_3027758_2 PFAM transglutaminase domain protein K22452 - 2.3.2.13 1.445e-200 644.0
CMS2_k127_3027758_20 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000001335 177.0
CMS2_k127_3027758_21 protein possibly involved in utilization of glycolate and propanediol - - - 0.000000000000000000000000000000000008338 143.0
CMS2_k127_3027758_22 - - - - 0.000000000000000000000000000001715 124.0
CMS2_k127_3027758_23 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000176 90.0
CMS2_k127_3027758_24 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000005943 71.0
CMS2_k127_3027758_25 hydroperoxide reductase activity K07486 - - 0.000002012 55.0
CMS2_k127_3027758_26 SMART Diguanylate phosphodiesterase - - - 0.00000958 53.0
CMS2_k127_3027758_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 491.0
CMS2_k127_3027758_4 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 450.0
CMS2_k127_3027758_5 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 456.0
CMS2_k127_3027758_6 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 423.0
CMS2_k127_3027758_7 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 420.0
CMS2_k127_3027758_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 370.0
CMS2_k127_3027758_9 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 320.0
CMS2_k127_3053800_0 Molecular chaperone. Has ATPase activity K04079 - - 2.438e-309 958.0
CMS2_k127_3053800_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 527.0
CMS2_k127_3053800_10 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001226 284.0
CMS2_k127_3053800_11 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002612 280.0
CMS2_k127_3053800_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001551 266.0
CMS2_k127_3053800_13 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000001478 227.0
CMS2_k127_3053800_14 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000001625 212.0
CMS2_k127_3053800_15 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000005034 208.0
CMS2_k127_3053800_16 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000169 205.0
CMS2_k127_3053800_17 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000002287 200.0
CMS2_k127_3053800_18 SpoIIAA-like - - - 0.0000000000000000000000000005052 117.0
CMS2_k127_3053800_19 - - - - 0.0000000000000000003021 89.0
CMS2_k127_3053800_2 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 483.0
CMS2_k127_3053800_21 Tripartite tricarboxylate transporter TctB family - - - 0.00005363 51.0
CMS2_k127_3053800_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 434.0
CMS2_k127_3053800_4 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 398.0
CMS2_k127_3053800_5 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 366.0
CMS2_k127_3053800_6 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 343.0
CMS2_k127_3053800_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 328.0
CMS2_k127_3053800_8 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 304.0
CMS2_k127_3053800_9 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005119 283.0
CMS2_k127_3066344_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1265.0
CMS2_k127_3066344_1 Extracellular solute-binding protein - - - 6.383e-321 1000.0
CMS2_k127_3066344_10 - - - - 0.0000000002421 60.0
CMS2_k127_3066344_11 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000007943 48.0
CMS2_k127_3066344_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 1.007e-276 866.0
CMS2_k127_3066344_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 615.0
CMS2_k127_3066344_4 Oligopeptide transport system permease protein OppB K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 509.0
CMS2_k127_3066344_5 Peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 501.0
CMS2_k127_3066344_6 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 467.0
CMS2_k127_3066344_7 LysM domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 384.0
CMS2_k127_3066344_8 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 373.0
CMS2_k127_3066344_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000005391 126.0
CMS2_k127_3106779_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.719e-215 694.0
CMS2_k127_3106779_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 6.909e-204 659.0
CMS2_k127_3106779_10 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 307.0
CMS2_k127_3106779_11 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000269 285.0
CMS2_k127_3106779_12 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003776 260.0
CMS2_k127_3106779_13 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001833 254.0
CMS2_k127_3106779_14 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000008353 229.0
CMS2_k127_3106779_15 Enoyl-CoA hydratase/isomerase K01661,K07536 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000007578 233.0
CMS2_k127_3106779_16 Pfam Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000001237 218.0
CMS2_k127_3106779_17 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000009377 224.0
CMS2_k127_3106779_18 - - - - 0.0000000000000000000000000000000000000000000000000000009237 200.0
CMS2_k127_3106779_19 toluene tolerance family protein K07323 - - 0.00000000000000000000000000000000000000004403 158.0
CMS2_k127_3106779_2 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 601.0
CMS2_k127_3106779_20 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.00000000000000000000000000000000000005538 147.0
CMS2_k127_3106779_21 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000004422 143.0
CMS2_k127_3106779_3 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 462.0
CMS2_k127_3106779_4 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 447.0
CMS2_k127_3106779_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 442.0
CMS2_k127_3106779_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 418.0
CMS2_k127_3106779_7 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 379.0
CMS2_k127_3106779_8 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 349.0
CMS2_k127_3106779_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 336.0
CMS2_k127_3211794_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1437.0
CMS2_k127_3211794_1 Belongs to the TPP enzyme family K01577 - 4.1.1.8 0.0 1012.0
CMS2_k127_3211794_10 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
CMS2_k127_3211794_11 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000007799 171.0
CMS2_k127_3211794_12 Universal stress protein family - - - 0.00000000000000000000000000000000003353 139.0
CMS2_k127_3211794_13 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000004008 125.0
CMS2_k127_3211794_14 Protein tyrosine kinase K12132 - 2.7.11.1 0.00002766 53.0
CMS2_k127_3211794_2 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 3.147e-296 915.0
CMS2_k127_3211794_3 24 kD subunit K00122 - 1.17.1.9 1.168e-270 842.0
CMS2_k127_3211794_4 Tripartite tricarboxylate transporter TctA family K07793 - - 1.325e-258 804.0
CMS2_k127_3211794_5 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 575.0
CMS2_k127_3211794_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 499.0
CMS2_k127_3211794_7 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 452.0
CMS2_k127_3211794_8 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 331.0
CMS2_k127_3211794_9 membrane protein, terc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 286.0
CMS2_k127_3214465_0 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 346.0
CMS2_k127_3214465_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 354.0
CMS2_k127_3214465_10 HNH endonuclease - - - 0.0000000000000000000002352 100.0
CMS2_k127_3214465_11 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.00000000000006645 83.0
CMS2_k127_3214465_12 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000002628 81.0
CMS2_k127_3214465_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 293.0
CMS2_k127_3214465_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000267 228.0
CMS2_k127_3214465_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000851 223.0
CMS2_k127_3214465_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000124 221.0
CMS2_k127_3214465_6 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000006612 175.0
CMS2_k127_3214465_7 - - - - 0.0000000000000000000000000000000001085 139.0
CMS2_k127_3214465_8 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.0000000000000000000000000000002131 137.0
CMS2_k127_3214465_9 Phosphotransferase enzyme family - - - 0.0000000000000000000001034 106.0
CMS2_k127_3221972_0 PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A K01908 - 6.2.1.17 2.237e-313 974.0
CMS2_k127_3221972_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.922e-228 722.0
CMS2_k127_3221972_10 - - - - 0.0000000000000000000000000000000000000000009765 167.0
CMS2_k127_3221972_11 carbon utilization - - - 0.00000000000000000002413 100.0
CMS2_k127_3221972_12 - - - - 0.0000000000000004923 86.0
CMS2_k127_3221972_13 - - - - 0.000000003021 68.0
CMS2_k127_3221972_2 Secretin and TonB N terminus short domain K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 550.0
CMS2_k127_3221972_3 PFAM type II secretion system K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 443.0
CMS2_k127_3221972_4 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 411.0
CMS2_k127_3221972_5 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 398.0
CMS2_k127_3221972_6 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000001925 213.0
CMS2_k127_3221972_7 prepilin-type N-terminal cleavage methylation K02456 - - 0.0000000000000000000000000000000000000000000000000000000004409 211.0
CMS2_k127_3221972_8 Type II secretory pathway pseudopilin - - - 0.000000000000000000000000000000000000000000000112 175.0
CMS2_k127_3221972_9 prepilin-type N-terminal cleavage methylation K02456 - - 0.0000000000000000000000000000000000000000000001166 171.0
CMS2_k127_326004_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1555.0
CMS2_k127_326004_1 SMART Tetratricopeptide domain protein - - - 1.7e-227 721.0
CMS2_k127_326004_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000005816 210.0
CMS2_k127_326004_11 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000001588 162.0
CMS2_k127_326004_12 - - - - 0.000000000000000000007235 97.0
CMS2_k127_326004_13 (Lipo)protein - - - 0.0000000000000000007378 94.0
CMS2_k127_326004_14 (Lipo)protein - - - 0.00000000000000002039 89.0
CMS2_k127_326004_15 SmpA / OmlA family - - - 0.0000000000002563 78.0
CMS2_k127_326004_2 Alanine-glyoxylate amino-transferase K00375,K05825 - - 1.495e-209 658.0
CMS2_k127_326004_3 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 561.0
CMS2_k127_326004_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 494.0
CMS2_k127_326004_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 383.0
CMS2_k127_326004_6 PFAM FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 314.0
CMS2_k127_326004_7 VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007835 248.0
CMS2_k127_326004_8 Putative beta-barrel porin 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000004216 237.0
CMS2_k127_326004_9 Pfam SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000003596 222.0
CMS2_k127_3293487_0 Protein of unknown function (DUF3141) - - - 0.0 1050.0
CMS2_k127_3293487_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1038.0
CMS2_k127_3293487_10 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 537.0
CMS2_k127_3293487_11 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 527.0
CMS2_k127_3293487_12 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 498.0
CMS2_k127_3293487_13 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 457.0
CMS2_k127_3293487_14 Malate/L-lactate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 451.0
CMS2_k127_3293487_15 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 443.0
CMS2_k127_3293487_16 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 449.0
CMS2_k127_3293487_17 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 440.0
CMS2_k127_3293487_18 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 434.0
CMS2_k127_3293487_19 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 414.0
CMS2_k127_3293487_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 4.814e-248 783.0
CMS2_k127_3293487_20 TIGRFAM 3-hydroxybutyrate dehydrogenase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 393.0
CMS2_k127_3293487_21 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 391.0
CMS2_k127_3293487_22 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 379.0
CMS2_k127_3293487_23 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 371.0
CMS2_k127_3293487_24 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 362.0
CMS2_k127_3293487_25 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 365.0
CMS2_k127_3293487_26 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 366.0
CMS2_k127_3293487_27 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 341.0
CMS2_k127_3293487_28 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 345.0
CMS2_k127_3293487_29 Thioredoxin-like K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 344.0
CMS2_k127_3293487_3 TonB dependent receptor K02014 - - 2.533e-227 726.0
CMS2_k127_3293487_30 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 329.0
CMS2_k127_3293487_31 Secreted protein, containing von Willebrand factor (VWF) type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 328.0
CMS2_k127_3293487_32 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 307.0
CMS2_k127_3293487_33 Pfam MotA TolQ ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 293.0
CMS2_k127_3293487_34 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009308 293.0
CMS2_k127_3293487_35 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001909 295.0
CMS2_k127_3293487_36 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007354 284.0
CMS2_k127_3293487_37 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000744 284.0
CMS2_k127_3293487_38 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000005078 267.0
CMS2_k127_3293487_39 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 255.0
CMS2_k127_3293487_4 PLD-like domain K06132 - - 3.337e-206 652.0
CMS2_k127_3293487_40 paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001104 251.0
CMS2_k127_3293487_41 low molecular weight K03741,K03892 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000001178 250.0
CMS2_k127_3293487_42 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.00000000000000000000000000000000000000000000000000000000000008621 216.0
CMS2_k127_3293487_43 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000002764 216.0
CMS2_k127_3293487_44 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000007141 217.0
CMS2_k127_3293487_45 - - - - 0.000000000000000000000000000000000000000000000000000000000008967 213.0
CMS2_k127_3293487_46 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000002458 209.0
CMS2_k127_3293487_47 - - - - 0.00000000000000000000000000000000000000000000000000000005487 204.0
CMS2_k127_3293487_48 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000000000002526 198.0
CMS2_k127_3293487_49 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000000000000000000000000007058 192.0
CMS2_k127_3293487_5 AsmA family K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 605.0
CMS2_k127_3293487_50 Evidence 4 Homologs of previously reported genes of K09700 - - 0.0000000000000000000000000000000000000000000000000006657 185.0
CMS2_k127_3293487_51 protein conserved in bacteria K11719 - - 0.0000000000000000000000000000000000000000000001224 175.0
CMS2_k127_3293487_52 PFAM Paraquat-inducible protein A K03808 - - 0.0000000000000000000000000000000000000000000001894 178.0
CMS2_k127_3293487_53 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000002878 189.0
CMS2_k127_3293487_54 Sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000000000004005 151.0
CMS2_k127_3293487_55 MlaC protein K07323 - - 0.0000000000000000000000000000000000000004979 158.0
CMS2_k127_3293487_56 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.00000000000000000000000000000000000002582 147.0
CMS2_k127_3293487_57 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.00000000000000000000000000000000003031 142.0
CMS2_k127_3293487_58 PFAM 17 kDa surface antigen - - - 0.0000000000000000000000000000000002217 139.0
CMS2_k127_3293487_59 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000000002982 139.0
CMS2_k127_3293487_6 Sigma-54 interaction domain K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 588.0
CMS2_k127_3293487_60 lipid catabolic process - - - 0.00000000000000000000000000000007938 138.0
CMS2_k127_3293487_61 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000006734 107.0
CMS2_k127_3293487_62 - - - - 0.000000000000000000000003431 104.0
CMS2_k127_3293487_63 ThiS family K03154 - - 0.00000000000000000003473 93.0
CMS2_k127_3293487_64 Prokaryotic N-terminal methylation motif - - - 0.0000000000002988 75.0
CMS2_k127_3293487_66 - - - - 0.0000000000726 74.0
CMS2_k127_3293487_67 - - - - 0.000000007007 65.0
CMS2_k127_3293487_69 - - - - 0.00000294 52.0
CMS2_k127_3293487_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 574.0
CMS2_k127_3293487_70 Hinge domain of cleavage stimulation factor subunit 2 K14407 - - 0.0002039 47.0
CMS2_k127_3293487_8 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 565.0
CMS2_k127_3293487_9 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 536.0
CMS2_k127_3380366_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.084e-300 949.0
CMS2_k127_3380366_1 Fumarase C C-terminus K01744 - 4.3.1.1 1.873e-257 798.0
CMS2_k127_3380366_10 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 520.0
CMS2_k127_3380366_11 Protein conserved in bacteria K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 503.0
CMS2_k127_3380366_12 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 498.0
CMS2_k127_3380366_13 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 501.0
CMS2_k127_3380366_14 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 486.0
CMS2_k127_3380366_15 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 478.0
CMS2_k127_3380366_16 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 471.0
CMS2_k127_3380366_17 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 474.0
CMS2_k127_3380366_18 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 455.0
CMS2_k127_3380366_19 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 396.0
CMS2_k127_3380366_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.14e-245 771.0
CMS2_k127_3380366_20 Including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 387.0
CMS2_k127_3380366_21 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 358.0
CMS2_k127_3380366_22 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058,K03778 - 1.1.1.28,1.1.1.29,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 360.0
CMS2_k127_3380366_23 luciferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 354.0
CMS2_k127_3380366_24 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 362.0
CMS2_k127_3380366_25 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 353.0
CMS2_k127_3380366_26 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 334.0
CMS2_k127_3380366_27 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 331.0
CMS2_k127_3380366_28 FecCD transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 329.0
CMS2_k127_3380366_29 protocatechuate 3,4-dioxygenase, beta subunit' K03381 - 1.13.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 327.0
CMS2_k127_3380366_3 BT1 family - - - 5.205e-238 748.0
CMS2_k127_3380366_30 flavin adenine dinucleotide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 321.0
CMS2_k127_3380366_31 Belongs to the UPF0255 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 318.0
CMS2_k127_3380366_32 KR domain K10780 - 1.3.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 310.0
CMS2_k127_3380366_33 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 308.0
CMS2_k127_3380366_34 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 296.0
CMS2_k127_3380366_35 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 292.0
CMS2_k127_3380366_36 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000359 289.0
CMS2_k127_3380366_37 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 292.0
CMS2_k127_3380366_38 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 282.0
CMS2_k127_3380366_39 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002487 284.0
CMS2_k127_3380366_4 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.19e-232 732.0
CMS2_k127_3380366_40 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001217 261.0
CMS2_k127_3380366_41 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000008718 252.0
CMS2_k127_3380366_42 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000004613 247.0
CMS2_k127_3380366_43 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001307 246.0
CMS2_k127_3380366_44 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000004464 245.0
CMS2_k127_3380366_45 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000002276 237.0
CMS2_k127_3380366_46 lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000002262 246.0
CMS2_k127_3380366_47 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000005925 228.0
CMS2_k127_3380366_48 Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000001688 225.0
CMS2_k127_3380366_49 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000005425 228.0
CMS2_k127_3380366_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 7.899e-226 721.0
CMS2_k127_3380366_50 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000002199 221.0
CMS2_k127_3380366_51 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000001017 206.0
CMS2_k127_3380366_52 Phospholipid N-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000519 187.0
CMS2_k127_3380366_53 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000007298 179.0
CMS2_k127_3380366_54 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000002667 183.0
CMS2_k127_3380366_55 membrane - - - 0.00000000000000000000000000000000000000000000005835 173.0
CMS2_k127_3380366_56 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000009916 167.0
CMS2_k127_3380366_57 Phosphopantetheine attachment site - - - 0.00000000000000000000000000000000000000005113 158.0
CMS2_k127_3380366_58 - - - - 0.000000000000000000000000000000000000002597 157.0
CMS2_k127_3380366_59 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000004454 151.0
CMS2_k127_3380366_6 SMART Elongator protein 3 MiaB NifB - - - 2.174e-200 636.0
CMS2_k127_3380366_60 S4 RNA-binding domain - - - 0.000000000000000000000000000000000000007483 149.0
CMS2_k127_3380366_61 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000008341 136.0
CMS2_k127_3380366_62 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000008793 144.0
CMS2_k127_3380366_63 FabA-like domain - - - 0.000000000000000000000000000000003224 140.0
CMS2_k127_3380366_64 - - - - 0.0000000000000000000000000000001117 131.0
CMS2_k127_3380366_65 - - - - 0.000000000000000000000000000000286 130.0
CMS2_k127_3380366_66 PFAM (2R)-phospho-3-sulfolactate synthase ComA K08097 - 4.4.1.19 0.000000000000000000000000000001645 132.0
CMS2_k127_3380366_67 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000611 119.0
CMS2_k127_3380366_68 Methyltransferase - - - 0.00000000000000000000000000007992 125.0
CMS2_k127_3380366_69 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000002865 121.0
CMS2_k127_3380366_7 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 579.0
CMS2_k127_3380366_70 - - - - 0.0000000000000000000000006435 106.0
CMS2_k127_3380366_71 Glycine-zipper domain - - - 0.000000000000000000000002513 109.0
CMS2_k127_3380366_72 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000001561 96.0
CMS2_k127_3380366_73 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000002798 96.0
CMS2_k127_3380366_74 decarboxylase K01607 - 4.1.1.44 0.0000000000000008728 84.0
CMS2_k127_3380366_75 Pfam:DUF1049 - - - 0.0000003559 55.0
CMS2_k127_3380366_76 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000005462 59.0
CMS2_k127_3380366_77 Phosphate starvation-inducible protein, PSIF - - - 0.00001271 50.0
CMS2_k127_3380366_78 - - - - 0.0000178 55.0
CMS2_k127_3380366_79 Tripartite tricarboxylate transporter TctB family - - - 0.0002211 51.0
CMS2_k127_3380366_8 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 550.0
CMS2_k127_3380366_9 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 539.0
CMS2_k127_3385660_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 3.372e-236 743.0
CMS2_k127_3385660_1 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 582.0
CMS2_k127_3385660_10 - - - - 0.0000000000009285 72.0
CMS2_k127_3385660_11 - - - - 0.000000000000976 71.0
CMS2_k127_3385660_12 - - - - 0.000000000001636 70.0
CMS2_k127_3385660_13 - - - - 0.00002133 50.0
CMS2_k127_3385660_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 570.0
CMS2_k127_3385660_3 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 535.0
CMS2_k127_3385660_4 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 455.0
CMS2_k127_3385660_5 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 320.0
CMS2_k127_3385660_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 303.0
CMS2_k127_3385660_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 297.0
CMS2_k127_3385660_8 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002835 266.0
CMS2_k127_3385660_9 COG2031 Short chain fatty acids transporter K02106 - - 0.00000000000000000000000000000000000000000000000000000001462 203.0
CMS2_k127_3387433_0 Periplasmic binding protein K01999 - - 2.613e-197 625.0
CMS2_k127_3387433_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 514.0
CMS2_k127_3387433_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 413.0
CMS2_k127_3459298_0 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 505.0
CMS2_k127_3459298_1 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 491.0
CMS2_k127_3459298_10 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000003929 131.0
CMS2_k127_3459298_11 - - - - 0.00000000000000000000004737 110.0
CMS2_k127_3459298_12 - - - - 0.00000008098 59.0
CMS2_k127_3459298_13 DNA-sulfur modification-associated - - - 0.0000003012 62.0
CMS2_k127_3459298_14 EF-hand domain pair - - - 0.000001934 57.0
CMS2_k127_3459298_2 Twin-arginine translocation pathway signal sequence - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 460.0
CMS2_k127_3459298_3 histidine kinase HAMP region domain protein K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 419.0
CMS2_k127_3459298_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 365.0
CMS2_k127_3459298_5 Peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007004 262.0
CMS2_k127_3459298_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000003053 225.0
CMS2_k127_3459298_7 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000001721 151.0
CMS2_k127_3459298_8 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000001353 151.0
CMS2_k127_3459298_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000004405 151.0
CMS2_k127_3460591_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1969.0
CMS2_k127_3460591_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 6.989e-312 966.0
CMS2_k127_3460591_10 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 579.0
CMS2_k127_3460591_11 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 574.0
CMS2_k127_3460591_12 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 551.0
CMS2_k127_3460591_13 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 529.0
CMS2_k127_3460591_14 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 490.0
CMS2_k127_3460591_15 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 413.0
CMS2_k127_3460591_16 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 403.0
CMS2_k127_3460591_17 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 394.0
CMS2_k127_3460591_18 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 329.0
CMS2_k127_3460591_19 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 318.0
CMS2_k127_3460591_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.011e-278 861.0
CMS2_k127_3460591_20 rRNA small subunit methyltransferase G K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000003255 232.0
CMS2_k127_3460591_21 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000003344 204.0
CMS2_k127_3460591_22 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000003978 212.0
CMS2_k127_3460591_23 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000009415 190.0
CMS2_k127_3460591_24 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000000000000001131 190.0
CMS2_k127_3460591_25 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000007291 179.0
CMS2_k127_3460591_26 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000009133 175.0
CMS2_k127_3460591_27 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000001367 162.0
CMS2_k127_3460591_28 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000006169 141.0
CMS2_k127_3460591_29 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000001575 83.0
CMS2_k127_3460591_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.539e-271 846.0
CMS2_k127_3460591_30 ATP synthase I chain - - - 0.00001497 53.0
CMS2_k127_3460591_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.284e-265 820.0
CMS2_k127_3460591_5 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 2.984e-244 761.0
CMS2_k127_3460591_6 Arginyl-tRNA synthetase K01887 - 6.1.1.19 5.85e-244 766.0
CMS2_k127_3460591_7 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.589e-231 737.0
CMS2_k127_3460591_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 6.393e-222 701.0
CMS2_k127_3460591_9 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.538e-198 626.0
CMS2_k127_34981_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004284 256.0
CMS2_k127_34981_1 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000002674 185.0
CMS2_k127_34981_2 Putative transposase of IS4/5 family (DUF4096) - - - 0.0000000000000000000000000005277 117.0
CMS2_k127_350962_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 592.0
CMS2_k127_350962_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 424.0
CMS2_k127_350962_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 385.0
CMS2_k127_350962_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 348.0
CMS2_k127_350962_4 preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000000002951 143.0
CMS2_k127_3520553_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1034.0
CMS2_k127_3520553_1 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 362.0
CMS2_k127_3520553_2 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002157 256.0
CMS2_k127_3520553_3 ferredoxin - - - 0.00000000000000000000000000003657 118.0
CMS2_k127_3520553_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000001889 81.0
CMS2_k127_3568768_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1274.0
CMS2_k127_3568768_1 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 612.0
CMS2_k127_3568768_10 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000003713 140.0
CMS2_k127_3568768_2 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 603.0
CMS2_k127_3568768_3 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 406.0
CMS2_k127_3568768_4 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 327.0
CMS2_k127_3568768_5 Glycosyl Transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003486 248.0
CMS2_k127_3568768_6 Beta-ketoacyl synthase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000009252 222.0
CMS2_k127_3568768_7 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000004645 218.0
CMS2_k127_3568768_8 Electron transfer DM13 - - - 0.000000000000000000000000000000000000000000000000002547 188.0
CMS2_k127_3568768_9 dehydratase - - - 0.000000000000000000000000000000000000004679 153.0
CMS2_k127_3647369_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1431.0
CMS2_k127_3647369_1 poly(R)-hydroxyalkanoic acid synthase K03821 - - 2.908e-254 799.0
CMS2_k127_3647369_10 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K20023 - 4.2.1.156,4.2.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 492.0
CMS2_k127_3647369_11 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 488.0
CMS2_k127_3647369_12 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 471.0
CMS2_k127_3647369_13 Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 441.0
CMS2_k127_3647369_14 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 422.0
CMS2_k127_3647369_15 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 409.0
CMS2_k127_3647369_16 TIGRFAM alpha-L-glutamate ligase-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 394.0
CMS2_k127_3647369_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 394.0
CMS2_k127_3647369_18 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 367.0
CMS2_k127_3647369_19 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 366.0
CMS2_k127_3647369_2 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 3.505e-234 733.0
CMS2_k127_3647369_20 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 365.0
CMS2_k127_3647369_21 single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 365.0
CMS2_k127_3647369_22 Transport permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 341.0
CMS2_k127_3647369_23 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 329.0
CMS2_k127_3647369_24 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 326.0
CMS2_k127_3647369_25 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 308.0
CMS2_k127_3647369_26 Domain of unknown function (DUF2437) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 287.0
CMS2_k127_3647369_27 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604,K11175 GO:0003674,GO:0003824,GO:0004479,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0042802,GO:0042803,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044419,GO:0046483,GO:0046983,GO:0051704,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.2,2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007682 289.0
CMS2_k127_3647369_28 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006471 284.0
CMS2_k127_3647369_29 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008962 265.0
CMS2_k127_3647369_3 Translation, ribosomal structure and biogenesis K08301 - - 8.543e-228 713.0
CMS2_k127_3647369_30 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002254 251.0
CMS2_k127_3647369_31 SEC-C Motif Domain Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001129 245.0
CMS2_k127_3647369_32 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000002297 241.0
CMS2_k127_3647369_33 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000000002851 232.0
CMS2_k127_3647369_34 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000006181 234.0
CMS2_k127_3647369_35 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000007247 228.0
CMS2_k127_3647369_36 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000000000007374 209.0
CMS2_k127_3647369_37 VanZ like family - - - 0.0000000000000000000000000000000000000000000000000000000001029 220.0
CMS2_k127_3647369_38 YGGT family K02221 - - 0.0000000000000000000000000000000000000000000000000000001091 202.0
CMS2_k127_3647369_39 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000003814 182.0
CMS2_k127_3647369_4 twitching motility protein K02669 - - 9.66e-200 624.0
CMS2_k127_3647369_40 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000801 200.0
CMS2_k127_3647369_41 Ferredoxin - - - 0.000000000000000000000000000000000000000000000007113 174.0
CMS2_k127_3647369_42 Histidine triad (HIT) - - - 0.000000000000000000000000000000000000000000001824 168.0
CMS2_k127_3647369_43 membrane - - - 0.00000000000000000000000000000000000000000001063 165.0
CMS2_k127_3647369_44 protein conserved in bacteria K03690 - - 0.00000000000000000000000000000000000000001581 162.0
CMS2_k127_3647369_45 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000001048 144.0
CMS2_k127_3647369_46 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000005463 143.0
CMS2_k127_3647369_47 MazG-like family - - - 0.00000000000000000000000000000000007242 139.0
CMS2_k127_3647369_48 Putative ATP-dependant zinc protease - - - 0.0000000000000000000000000006103 121.0
CMS2_k127_3647369_49 - - - - 0.0000000000000000000000000007012 121.0
CMS2_k127_3647369_5 twitching motility protein K02670 - - 9.241e-197 625.0
CMS2_k127_3647369_51 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.000000000000000000003512 106.0
CMS2_k127_3647369_52 Belongs to the UPF0235 family K09131 - - 0.000000000000000000009832 99.0
CMS2_k127_3647369_53 - - - - 0.000000000000009766 79.0
CMS2_k127_3647369_54 PFAM porin, Gram-negative type - - - 0.00009159 48.0
CMS2_k127_3647369_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 600.0
CMS2_k127_3647369_7 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 542.0
CMS2_k127_3647369_8 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 527.0
CMS2_k127_3647369_9 Belongs to the DegT DnrJ EryC1 family K20429 - 2.6.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 526.0
CMS2_k127_3687305_0 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 441.0
CMS2_k127_3687305_1 - - - - 0.00000000000000000996 97.0
CMS2_k127_3690378_0 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 3.298e-207 649.0
CMS2_k127_3690378_1 ABC-type multidrug transport system, ATPase and permease K06147 - - 5.595e-200 639.0
CMS2_k127_3690378_10 Belongs to the CinA family - - - 0.00000000000000000000000000000000000000000008571 164.0
CMS2_k127_3690378_11 methyltransferase activity - - - 0.000000000000000000000000000000000000000008273 158.0
CMS2_k127_3690378_12 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000005534 156.0
CMS2_k127_3690378_13 Rhodanese-like domain - - - 0.0000000000000000000000000003297 124.0
CMS2_k127_3690378_14 PFAM amidohydrolase 2 - - - 0.00000000000006151 72.0
CMS2_k127_3690378_15 WD40-like Beta Propeller Repeat - - - 0.00002407 57.0
CMS2_k127_3690378_2 acyl-CoA dehydrogenase - - - 1.047e-196 623.0
CMS2_k127_3690378_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 366.0
CMS2_k127_3690378_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 320.0
CMS2_k127_3690378_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 292.0
CMS2_k127_3690378_6 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000001151 238.0
CMS2_k127_3690378_7 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.0000000000000000000000000000000000000000000000000000000001138 214.0
CMS2_k127_3690378_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000001215 200.0
CMS2_k127_3690378_9 chorismate binding enzyme - - - 0.00000000000000000000000000000000000000000004111 164.0
CMS2_k127_3701009_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1209.0
CMS2_k127_3701009_1 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 417.0
CMS2_k127_3701009_2 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 284.0
CMS2_k127_3701009_3 - - - - 0.00000000000000000000000000000001075 133.0
CMS2_k127_3796233_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006396 268.0
CMS2_k127_3796233_1 - - - - 0.00000000000000000000002725 108.0
CMS2_k127_390385_0 4Fe-4S dicluster domain - - - 0.0 1275.0
CMS2_k127_390385_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.991e-232 732.0
CMS2_k127_390385_10 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 305.0
CMS2_k127_390385_11 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 293.0
CMS2_k127_390385_12 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 291.0
CMS2_k127_390385_13 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 286.0
CMS2_k127_390385_14 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 288.0
CMS2_k127_390385_15 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006145 270.0
CMS2_k127_390385_16 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000001492 242.0
CMS2_k127_390385_17 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000003672 233.0
CMS2_k127_390385_18 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000000000000000000000000000000000004046 222.0
CMS2_k127_390385_19 - - - - 0.00000000000000000000000000000000000000000000000000004845 195.0
CMS2_k127_390385_2 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 4.915e-196 617.0
CMS2_k127_390385_20 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000003078 184.0
CMS2_k127_390385_21 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000000000013 158.0
CMS2_k127_390385_22 Restriction endonuclease K07448 - - 0.000000000000000000000000000000009334 137.0
CMS2_k127_390385_23 ornithine cyclodeaminase K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000007709 128.0
CMS2_k127_390385_24 NMT1-like family K07080 - - 0.00000000000000000000000001182 122.0
CMS2_k127_390385_25 23S rRNA-intervening sequence protein - - - 0.0000000000000000000001907 101.0
CMS2_k127_390385_26 Belongs to the TPP enzyme family - - - 0.00000000000000000002178 99.0
CMS2_k127_390385_27 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.0000000000002465 80.0
CMS2_k127_390385_28 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K21062 - 3.5.4.22,4.3.3.7 0.00002906 52.0
CMS2_k127_390385_3 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 521.0
CMS2_k127_390385_4 glutamate--cysteine ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 527.0
CMS2_k127_390385_5 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 471.0
CMS2_k127_390385_6 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 443.0
CMS2_k127_390385_7 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 410.0
CMS2_k127_390385_8 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 434.0
CMS2_k127_390385_9 PFAM Succinylglutamate desuccinylase Aspartoacylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 410.0
CMS2_k127_3933815_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1433.0
CMS2_k127_3933815_1 PFAM Glycoside hydrolase family 65, central catalytic - - - 0.0 1041.0
CMS2_k127_3933815_10 COG0526 Thiol-disulfide isomerase and thioredoxins K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000006974 167.0
CMS2_k127_3933815_11 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000000000927 149.0
CMS2_k127_3933815_12 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000004682 108.0
CMS2_k127_3933815_13 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000001567 82.0
CMS2_k127_3933815_2 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 2.186e-242 760.0
CMS2_k127_3933815_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 405.0
CMS2_k127_3933815_4 Amidohydrolase K10221 - 3.1.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 385.0
CMS2_k127_3933815_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 372.0
CMS2_k127_3933815_6 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 299.0
CMS2_k127_3933815_7 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003132 285.0
CMS2_k127_3933815_8 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002864 253.0
CMS2_k127_3933815_9 C4-dicarboxylate ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000006005 207.0
CMS2_k127_393428_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 9.198e-240 749.0
CMS2_k127_393428_1 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 4.265e-239 745.0
CMS2_k127_393428_10 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 327.0
CMS2_k127_393428_11 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000278 245.0
CMS2_k127_393428_12 COG3245 Cytochrome c5 - - - 0.00000000000000000000000000000000000000000000000000000000000000009099 240.0
CMS2_k127_393428_13 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000001956 217.0
CMS2_k127_393428_14 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000001824 203.0
CMS2_k127_393428_15 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000002852 203.0
CMS2_k127_393428_16 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000001505 198.0
CMS2_k127_393428_17 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000001804 192.0
CMS2_k127_393428_18 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000009195 174.0
CMS2_k127_393428_19 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000000000000000009047 168.0
CMS2_k127_393428_2 Thi4 family - - - 7.342e-220 694.0
CMS2_k127_393428_20 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000000002075 158.0
CMS2_k127_393428_21 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000003218 138.0
CMS2_k127_393428_22 MAPEG family - - - 0.0000000000000000000000000000006229 126.0
CMS2_k127_393428_23 - - - - 0.0000000000000000000001213 102.0
CMS2_k127_393428_24 Protein of unknown function (DUF2889) - - - 0.00000089 51.0
CMS2_k127_393428_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 2.126e-201 636.0
CMS2_k127_393428_4 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 6.434e-199 636.0
CMS2_k127_393428_5 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 490.0
CMS2_k127_393428_6 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 441.0
CMS2_k127_393428_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 396.0
CMS2_k127_393428_8 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 384.0
CMS2_k127_393428_9 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 344.0
CMS2_k127_3953255_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1444.0
CMS2_k127_3953255_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1298.0
CMS2_k127_3953255_10 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 542.0
CMS2_k127_3953255_11 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 527.0
CMS2_k127_3953255_12 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 532.0
CMS2_k127_3953255_13 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 479.0
CMS2_k127_3953255_14 lipoate-protein ligase A K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 452.0
CMS2_k127_3953255_15 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 445.0
CMS2_k127_3953255_16 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 435.0
CMS2_k127_3953255_17 Permease, YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 430.0
CMS2_k127_3953255_18 Permease, YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 363.0
CMS2_k127_3953255_19 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 363.0
CMS2_k127_3953255_2 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 5.83e-318 979.0
CMS2_k127_3953255_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 334.0
CMS2_k127_3953255_21 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 311.0
CMS2_k127_3953255_22 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 286.0
CMS2_k127_3953255_23 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001394 281.0
CMS2_k127_3953255_24 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004223 284.0
CMS2_k127_3953255_25 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006764 272.0
CMS2_k127_3953255_26 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009098 263.0
CMS2_k127_3953255_27 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009526 268.0
CMS2_k127_3953255_28 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009591 259.0
CMS2_k127_3953255_29 N-acetylmuramoyl-L-alanine amidase (Family 2) K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000001198 249.0
CMS2_k127_3953255_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.444e-265 827.0
CMS2_k127_3953255_30 RNA polymerase K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008055 245.0
CMS2_k127_3953255_31 Protein of unknown function (DUF2470) K07226 - - 0.000000000000000000000000000000000000000000000000000000004158 220.0
CMS2_k127_3953255_32 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000008434 201.0
CMS2_k127_3953255_33 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000002049 191.0
CMS2_k127_3953255_34 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000003656 192.0
CMS2_k127_3953255_35 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000001383 156.0
CMS2_k127_3953255_36 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000004158 143.0
CMS2_k127_3953255_37 Predicted membrane protein (DUF2069) - - - 0.00000000000000000000000000000005551 128.0
CMS2_k127_3953255_38 CNP1-like family - - - 0.00000000000000000000000000003258 128.0
CMS2_k127_3953255_39 RDD family - - - 0.000000000000000000000000002513 116.0
CMS2_k127_3953255_4 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.957e-261 812.0
CMS2_k127_3953255_40 Protein of unknown function (DUF2905) - - - 0.00000000000000000000001549 100.0
CMS2_k127_3953255_41 Protein of unknown function (DUF3106) - - - 0.00000000000000000000002639 109.0
CMS2_k127_3953255_42 Protein of unknown function (DUF3617) - - - 0.0000000000000000003036 94.0
CMS2_k127_3953255_43 Protein of unknown function (DUF3619) - - - 0.000000000000003879 82.0
CMS2_k127_3953255_44 - K06950 - - 0.000000000000867 70.0
CMS2_k127_3953255_45 Protein of unknown function (DUF2442) - - - 0.0000005674 56.0
CMS2_k127_3953255_5 Cysteine-rich domain - - - 4.614e-233 727.0
CMS2_k127_3953255_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 7.036e-208 657.0
CMS2_k127_3953255_7 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 7.643e-207 646.0
CMS2_k127_3953255_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 7.004e-204 658.0
CMS2_k127_3953255_9 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 546.0
CMS2_k127_4126932_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1049.0
CMS2_k127_4126932_1 helicase K03657 - 3.6.4.12 5.892e-225 715.0
CMS2_k127_4126932_10 4Fe-4S dicluster domain K05796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 288.0
CMS2_k127_4126932_11 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 289.0
CMS2_k127_4126932_12 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003357 286.0
CMS2_k127_4126932_13 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000104 261.0
CMS2_k127_4126932_14 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K21062 - 3.5.4.22,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000451 236.0
CMS2_k127_4126932_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000001337 214.0
CMS2_k127_4126932_16 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000005923 207.0
CMS2_k127_4126932_17 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K21062 - 3.5.4.22,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000001765 214.0
CMS2_k127_4126932_18 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000003393 188.0
CMS2_k127_4126932_19 Serine hydrolase K07002 - - 0.0000000000000000000000000000000000000000004575 164.0
CMS2_k127_4126932_2 FAD-dependent pyridine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 500.0
CMS2_k127_4126932_20 SpoIIAA-like - - - 0.0000000000000000000000000000000003087 135.0
CMS2_k127_4126932_21 Ornithine cyclodeaminase/mu-crystallin family K01750,K19742,K19743,K21721 - 1.5.1.1,1.5.1.49,1.5.1.51,4.3.1.12 0.00000000000000000000000000001521 132.0
CMS2_k127_4126932_22 Mut7-C ubiquitin - - - 0.00000000000000000000000231 109.0
CMS2_k127_4126932_23 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000002997 113.0
CMS2_k127_4126932_24 - - - - 0.000000000000000000009818 94.0
CMS2_k127_4126932_25 Endoribonuclease L-PSP K09022,K15067 - 3.5.99.10,3.5.99.5 0.00000000000003237 80.0
CMS2_k127_4126932_26 cellulase activity - - - 0.0000000000001359 79.0
CMS2_k127_4126932_27 - - - - 0.0000000000001908 75.0
CMS2_k127_4126932_28 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000003634 78.0
CMS2_k127_4126932_29 PilZ domain - - - 0.0000000007278 64.0
CMS2_k127_4126932_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 411.0
CMS2_k127_4126932_4 PFAM phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 381.0
CMS2_k127_4126932_5 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 362.0
CMS2_k127_4126932_6 acyl-CoA dehydrogenase K06446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 348.0
CMS2_k127_4126932_7 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 342.0
CMS2_k127_4126932_8 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 348.0
CMS2_k127_4126932_9 Protein of unknown function (DUF2167) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 302.0
CMS2_k127_4148997_0 TIGRFAM malate synthase A K01638 - 2.3.3.9 3.51e-254 793.0
CMS2_k127_4148997_1 PFAM AMP-dependent synthetase and ligase K00666 - - 1.307e-230 726.0
CMS2_k127_4148997_10 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 526.0
CMS2_k127_4148997_11 Trypsin K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 511.0
CMS2_k127_4148997_12 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 510.0
CMS2_k127_4148997_13 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 499.0
CMS2_k127_4148997_14 Taurine catabolism dioxygenase TauD, TfdA family K03119,K22303 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 438.0
CMS2_k127_4148997_15 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 439.0
CMS2_k127_4148997_16 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 385.0
CMS2_k127_4148997_17 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 352.0
CMS2_k127_4148997_18 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 342.0
CMS2_k127_4148997_19 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 303.0
CMS2_k127_4148997_2 Domain of Unknown Function (DUF748) - - - 3.065e-230 754.0
CMS2_k127_4148997_20 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008383 283.0
CMS2_k127_4148997_21 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001363 274.0
CMS2_k127_4148997_22 hydratase decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001856 280.0
CMS2_k127_4148997_23 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003168 279.0
CMS2_k127_4148997_24 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006738 277.0
CMS2_k127_4148997_25 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002007 263.0
CMS2_k127_4148997_26 protein conserved in bacteria K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007293 257.0
CMS2_k127_4148997_27 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007973 252.0
CMS2_k127_4148997_28 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000000000007047 202.0
CMS2_k127_4148997_29 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000006152 183.0
CMS2_k127_4148997_3 FAD dependent oxidoreductase - - - 6.689e-204 645.0
CMS2_k127_4148997_30 Cold shock protein K03704 - - 0.00000000000000000000000000000000002272 136.0
CMS2_k127_4148997_31 - - - - 0.000000000000000009972 85.0
CMS2_k127_4148997_32 - - - - 0.00000000000005036 78.0
CMS2_k127_4148997_33 OsmC-like protein - - - 0.0000000003479 67.0
CMS2_k127_4148997_34 Parallel beta-helix repeats - - - 0.000000006671 66.0
CMS2_k127_4148997_36 - - - - 0.00000003504 59.0
CMS2_k127_4148997_38 Translation elongation factor K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.000004675 49.0
CMS2_k127_4148997_4 MmgE PrpD family protein - - - 1.347e-197 625.0
CMS2_k127_4148997_5 Translation elongation factor K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 628.0
CMS2_k127_4148997_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 580.0
CMS2_k127_4148997_7 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 569.0
CMS2_k127_4148997_8 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 537.0
CMS2_k127_4148997_9 Pfam Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 528.0
CMS2_k127_41879_0 Polysaccharide biosynthesis protein - - - 2.335e-231 732.0
CMS2_k127_41879_1 Glycosyl transferase family 4 K13007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006546 278.0
CMS2_k127_4206093_0 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004889 265.0
CMS2_k127_4206093_1 O-methyltransferase - - - 0.0000000000000000000000000001443 120.0
CMS2_k127_4206093_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000003128 55.0
CMS2_k127_4206093_3 Putative addiction module component - - - 0.000003691 51.0
CMS2_k127_4224391_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 5.436e-270 842.0
CMS2_k127_4224391_1 Chromate transporter - - - 3.639e-200 635.0
CMS2_k127_4224391_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000009735 212.0
CMS2_k127_4224391_11 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000001511 208.0
CMS2_k127_4224391_12 Sulfurtransferase TusA - - - 0.000000000000000000000000000000000000000000000000000006622 194.0
CMS2_k127_4224391_13 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000005117 194.0
CMS2_k127_4224391_14 TIGRFAM CRISPR-associated protein - - - 0.000000000000000000000000000000000000000000000000000358 192.0
CMS2_k127_4224391_15 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000003002 171.0
CMS2_k127_4224391_16 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000002993 169.0
CMS2_k127_4224391_18 part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000000000000876 147.0
CMS2_k127_4224391_19 part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000000000002451 147.0
CMS2_k127_4224391_2 reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 514.0
CMS2_k127_4224391_20 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000000000000000000000816 135.0
CMS2_k127_4224391_21 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000001141 126.0
CMS2_k127_4224391_22 Sulfurtransferase TusA K04085 - - 0.000000000000000000000000000000153 125.0
CMS2_k127_4224391_23 - - - - 0.00000000000000000000000000001045 123.0
CMS2_k127_4224391_24 Peptidase S24-like - - - 0.00000000000000000000009296 100.0
CMS2_k127_4224391_25 - - - - 0.000000000000000000309 91.0
CMS2_k127_4224391_26 Belongs to the N-Me-Phe pilin family K02650 - - 0.0000000000001684 73.0
CMS2_k127_4224391_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 509.0
CMS2_k127_4224391_4 PFAM Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 485.0
CMS2_k127_4224391_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 338.0
CMS2_k127_4224391_6 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 304.0
CMS2_k127_4224391_7 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 295.0
CMS2_k127_4224391_8 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006067 250.0
CMS2_k127_4224391_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000008674 238.0
CMS2_k127_4274722_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 466.0
CMS2_k127_4274722_1 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004339 276.0
CMS2_k127_4274722_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000001383 72.0
CMS2_k127_4274722_3 - - - - 0.00000008366 57.0
CMS2_k127_4334165_0 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 297.0
CMS2_k127_4334165_1 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000003717 214.0
CMS2_k127_4361672_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 611.0
CMS2_k127_4361672_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 517.0
CMS2_k127_4361672_10 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004223 273.0
CMS2_k127_4361672_11 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001537 243.0
CMS2_k127_4361672_12 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000002123 244.0
CMS2_k127_4361672_13 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000005508 207.0
CMS2_k127_4361672_14 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000001016 171.0
CMS2_k127_4361672_15 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000001099 145.0
CMS2_k127_4361672_16 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000000000002365 134.0
CMS2_k127_4361672_17 Thioesterase superfamily K07107 - - 0.00000000000000000000000000000004938 132.0
CMS2_k127_4361672_18 membrane transporter protein K07090 - - 0.00000000000000000000000004726 117.0
CMS2_k127_4361672_19 Cold shock K03704 - - 0.00000000000000000000000007187 112.0
CMS2_k127_4361672_2 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 424.0
CMS2_k127_4361672_21 SnoaL-like polyketide cyclase - - - 0.000000000000000000000001126 109.0
CMS2_k127_4361672_22 - - - - 0.000000000000000000001389 99.0
CMS2_k127_4361672_23 membrane transporter protein K07090 - - 0.000000000000000001544 96.0
CMS2_k127_4361672_24 Belongs to the skp family K06142 - - 0.000000000000004901 83.0
CMS2_k127_4361672_25 - - - - 0.000000000000215 79.0
CMS2_k127_4361672_26 response regulator, receiver - - - 0.000000000003996 75.0
CMS2_k127_4361672_27 OsmC-like protein - - - 0.000000000007884 68.0
CMS2_k127_4361672_28 LTXXQ motif family protein - - - 0.00000000006143 70.0
CMS2_k127_4361672_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 404.0
CMS2_k127_4361672_30 Cupin - - - 0.00000001026 57.0
CMS2_k127_4361672_32 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000001076 59.0
CMS2_k127_4361672_4 Belongs to the TPP enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 376.0
CMS2_k127_4361672_5 Protein of unknown function (DUF1847) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 349.0
CMS2_k127_4361672_6 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 303.0
CMS2_k127_4361672_7 PFAM amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 300.0
CMS2_k127_4361672_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 291.0
CMS2_k127_4361672_9 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 291.0
CMS2_k127_4385757_0 binding-protein-dependent transport systems inner membrane component K02011 - - 1.121e-255 799.0
CMS2_k127_4385757_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.528e-216 685.0
CMS2_k127_4385757_10 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000368 284.0
CMS2_k127_4385757_11 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002318 241.0
CMS2_k127_4385757_12 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004165 237.0
CMS2_k127_4385757_13 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000001744 215.0
CMS2_k127_4385757_14 membrane - - - 0.000000000000000000000000000000000000000000000000000001123 200.0
CMS2_k127_4385757_15 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000000000000000000000000256 199.0
CMS2_k127_4385757_2 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 604.0
CMS2_k127_4385757_3 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 453.0
CMS2_k127_4385757_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 431.0
CMS2_k127_4385757_5 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 389.0
CMS2_k127_4385757_6 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 379.0
CMS2_k127_4385757_7 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 367.0
CMS2_k127_4385757_8 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 319.0
CMS2_k127_4385757_9 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000173 289.0
CMS2_k127_4387523_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.134e-293 907.0
CMS2_k127_4387523_1 Bacterial protein of unknown function (DUF853) K06915 - - 5.217e-214 675.0
CMS2_k127_4387523_10 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 508.0
CMS2_k127_4387523_11 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 496.0
CMS2_k127_4387523_12 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 492.0
CMS2_k127_4387523_13 transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 466.0
CMS2_k127_4387523_14 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 445.0
CMS2_k127_4387523_15 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 430.0
CMS2_k127_4387523_16 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 416.0
CMS2_k127_4387523_17 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 403.0
CMS2_k127_4387523_18 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 395.0
CMS2_k127_4387523_19 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 385.0
CMS2_k127_4387523_2 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 591.0
CMS2_k127_4387523_20 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 394.0
CMS2_k127_4387523_21 AAA domain K02450,K12283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 366.0
CMS2_k127_4387523_22 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 350.0
CMS2_k127_4387523_23 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 345.0
CMS2_k127_4387523_24 Queuosine biosynthesis protein QueC K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 334.0
CMS2_k127_4387523_25 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 333.0
CMS2_k127_4387523_26 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 320.0
CMS2_k127_4387523_27 Cell division ATP-binding protein ftsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 305.0
CMS2_k127_4387523_28 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 306.0
CMS2_k127_4387523_29 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004105 280.0
CMS2_k127_4387523_3 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 574.0
CMS2_k127_4387523_30 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001455 289.0
CMS2_k127_4387523_31 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002103 263.0
CMS2_k127_4387523_32 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002348 252.0
CMS2_k127_4387523_33 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003198 251.0
CMS2_k127_4387523_34 oxidase assembly K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000000003708 243.0
CMS2_k127_4387523_35 PFAM Fimbrial assembly family protein K12279 - - 0.000000000000000000000000000000000000000000000000000000000000000000006672 242.0
CMS2_k127_4387523_36 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000001232 241.0
CMS2_k127_4387523_37 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000005046 235.0
CMS2_k127_4387523_38 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000008344 240.0
CMS2_k127_4387523_39 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000088 236.0
CMS2_k127_4387523_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 562.0
CMS2_k127_4387523_40 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000005366 234.0
CMS2_k127_4387523_41 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000096 221.0
CMS2_k127_4387523_42 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000000000000002272 220.0
CMS2_k127_4387523_43 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000001325 211.0
CMS2_k127_4387523_44 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000001003 195.0
CMS2_k127_4387523_45 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000006331 194.0
CMS2_k127_4387523_46 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000001406 191.0
CMS2_k127_4387523_47 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000006467 190.0
CMS2_k127_4387523_48 Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000000000001474 177.0
CMS2_k127_4387523_49 Tetratricopeptide repeat K12284 - - 0.000000000000000000000000000000000000000000000002566 189.0
CMS2_k127_4387523_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 561.0
CMS2_k127_4387523_50 Ferredoxin - - - 0.000000000000000000000000000000000000000002774 156.0
CMS2_k127_4387523_51 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.00000000000000000000000000000000000000009872 155.0
CMS2_k127_4387523_52 TIGRFAM TonB family protein K03646 - - 0.0000000000000000000000000000000000002361 155.0
CMS2_k127_4387523_53 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000001256 142.0
CMS2_k127_4387523_54 Fimbrial assembly protein (PilN) - - - 0.0000000000000000000000000000000002889 140.0
CMS2_k127_4387523_55 carbon utilization K12280 - - 0.00000000000000000000000000000001294 136.0
CMS2_k127_4387523_56 Integral membrane protein (DUF2244) - - - 0.0000000000000000000003481 103.0
CMS2_k127_4387523_57 Protein of unknown function (DUF2909) - - - 0.00000000000001398 76.0
CMS2_k127_4387523_58 Ankyrin repeat K06867 - - 0.0000000000001164 81.0
CMS2_k127_4387523_59 - K12281 - - 0.000000000002095 76.0
CMS2_k127_4387523_6 type II and III secretion system protein K02453,K12282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 561.0
CMS2_k127_4387523_60 Protein of unknown function (DUF2970) - - - 0.00000002463 58.0
CMS2_k127_4387523_7 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 550.0
CMS2_k127_4387523_8 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 515.0
CMS2_k127_4387523_9 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 505.0
CMS2_k127_4408818_0 Gamma-glutamyltranspeptidase - - - 1.998e-230 727.0
CMS2_k127_4408818_1 Amidohydrolase K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 502.0
CMS2_k127_4408818_10 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 331.0
CMS2_k127_4408818_11 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 323.0
CMS2_k127_4408818_12 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 294.0
CMS2_k127_4408818_13 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007639 284.0
CMS2_k127_4408818_14 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009806 283.0
CMS2_k127_4408818_15 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000002544 259.0
CMS2_k127_4408818_16 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002515 250.0
CMS2_k127_4408818_17 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000000008083 207.0
CMS2_k127_4408818_18 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000001558 166.0
CMS2_k127_4408818_19 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000001153 141.0
CMS2_k127_4408818_2 PFAM Alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 449.0
CMS2_k127_4408818_20 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000005571 129.0
CMS2_k127_4408818_21 - - - - 0.000000000000000003803 90.0
CMS2_k127_4408818_22 Fumarylacetoacetate (FAA) hydrolase family K02554 - 4.2.1.80 0.00000000000000007664 89.0
CMS2_k127_4408818_23 Putative MetA-pathway of phenol degradation - - - 0.00000000002128 65.0
CMS2_k127_4408818_24 Putative MetA-pathway of phenol degradation - - - 0.0000000001465 68.0
CMS2_k127_4408818_25 Putative MetA-pathway of phenol degradation - - - 0.00000001469 62.0
CMS2_k127_4408818_3 Fad dependent oxidoreductase K00273 - 1.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 444.0
CMS2_k127_4408818_4 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 430.0
CMS2_k127_4408818_5 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 419.0
CMS2_k127_4408818_6 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 377.0
CMS2_k127_4408818_7 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 353.0
CMS2_k127_4408818_8 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 346.0
CMS2_k127_4408818_9 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 347.0
CMS2_k127_4484665_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007779 275.0
CMS2_k127_4484665_1 Glycosyl transferase family 2 K12984 - - 0.000000000000000000000000000000000000000000000000000006789 205.0
CMS2_k127_4484665_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000001604 92.0
CMS2_k127_4682330_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 583.0
CMS2_k127_4682330_1 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 555.0
CMS2_k127_4682330_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 515.0
CMS2_k127_4682330_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 434.0
CMS2_k127_4682330_4 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000001543 229.0
CMS2_k127_4745804_0 multicopper oxidase type 3 K22348 - 1.16.3.3 9.314e-236 735.0
CMS2_k127_4745804_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 530.0
CMS2_k127_4745804_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 419.0
CMS2_k127_4745804_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000004317 244.0
CMS2_k127_4745804_4 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000000000000000000003829 174.0
CMS2_k127_4745804_5 Copper binding periplasmic protein CusF - - - 0.00000000000000000000001289 105.0
CMS2_k127_4841607_0 PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 336.0
CMS2_k127_4841607_1 PFAM Cupin 2, conserved barrel K00450 - 1.13.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 340.0
CMS2_k127_4841607_2 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 314.0
CMS2_k127_4841607_3 PFAM amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009015 283.0
CMS2_k127_4841607_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001908 282.0
CMS2_k127_4841607_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006311 265.0
CMS2_k127_4841607_6 Amidohydrolase K03392,K22213 - 4.1.1.45,4.1.1.52 0.00000000000000000000000000000000000000000000000000000000000641 219.0
CMS2_k127_4841607_7 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000006223 213.0
CMS2_k127_4841607_8 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000002224 177.0
CMS2_k127_4841607_9 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000001771 134.0
CMS2_k127_4885476_0 protein related to plant photosystem II stability assembly factor - - - 2.547e-213 669.0
CMS2_k127_4885476_1 Coenzyme A transferase K01027,K01029,K01032 - 2.8.3.5,2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 544.0
CMS2_k127_4885476_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000003443 223.0
CMS2_k127_4885476_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000144 203.0
CMS2_k127_4885476_12 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000001306 210.0
CMS2_k127_4885476_13 1-phosphatidylinositol-4-phosphate 5-kinase activity - - - 0.0000000000000000000000000000000000000000000000000001965 202.0
CMS2_k127_4885476_14 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000003932 192.0
CMS2_k127_4885476_15 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.0000000000000000000000000000000000000000000000001219 186.0
CMS2_k127_4885476_16 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000004503 179.0
CMS2_k127_4885476_17 Multidrug transporter K08161 - - 0.0000000000000000000000000000000000000000000001431 183.0
CMS2_k127_4885476_18 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000007597 144.0
CMS2_k127_4885476_19 ThiS family K03636 - - 0.0000000000000000000000000000000001763 133.0
CMS2_k127_4885476_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 484.0
CMS2_k127_4885476_20 COG0006 Xaa-Pro aminopeptidase K01271 - 3.4.13.9 0.00000000000000000000000000000002309 141.0
CMS2_k127_4885476_21 - - - - 0.00000000000000004855 86.0
CMS2_k127_4885476_22 hydroperoxide reductase activity - - - 0.000000000000001616 78.0
CMS2_k127_4885476_23 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000001685 66.0
CMS2_k127_4885476_3 Amidohydrolase family K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 448.0
CMS2_k127_4885476_4 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 401.0
CMS2_k127_4885476_5 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009724 323.0
CMS2_k127_4885476_6 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 289.0
CMS2_k127_4885476_7 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 292.0
CMS2_k127_4885476_8 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008636 269.0
CMS2_k127_4885476_9 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000006956 264.0
CMS2_k127_4997369_0 CoA-binding domain protein K09181 - - 0.0 1105.0
CMS2_k127_4997369_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 2.968e-228 709.0
CMS2_k127_4997369_10 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 317.0
CMS2_k127_4997369_11 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 306.0
CMS2_k127_4997369_12 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001756 284.0
CMS2_k127_4997369_13 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002214 301.0
CMS2_k127_4997369_14 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006033 279.0
CMS2_k127_4997369_15 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001414 287.0
CMS2_k127_4997369_16 periplasmic protein thiol disulfide K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001499 259.0
CMS2_k127_4997369_17 plastoquinol--plastocyanin reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004886 255.0
CMS2_k127_4997369_18 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000004459 203.0
CMS2_k127_4997369_19 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000001493 198.0
CMS2_k127_4997369_2 homoserine dehydrogenase - - - 7.951e-220 689.0
CMS2_k127_4997369_20 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000001531 180.0
CMS2_k127_4997369_21 Protein of unknown function, DUF - - - 0.00000000000000000000000000000000000000000000005726 170.0
CMS2_k127_4997369_22 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000000000002372 171.0
CMS2_k127_4997369_23 FixH family K09926 - - 0.0000000000000000000000000000000000000003007 156.0
CMS2_k127_4997369_24 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000008112 152.0
CMS2_k127_4997369_25 - - - - 0.00000000000000000000000000000000000005902 150.0
CMS2_k127_4997369_26 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000000000000000000000000003362 150.0
CMS2_k127_4997369_27 - - - - 0.00000000000000000000000231 109.0
CMS2_k127_4997369_28 Sel1-like repeats. - - - 0.00000000000000000000006984 106.0
CMS2_k127_4997369_29 - - - - 0.0000000000000000000002234 108.0
CMS2_k127_4997369_3 cytochrome C oxidase - - - 5.497e-196 621.0
CMS2_k127_4997369_30 - - - - 0.0000000000000000000002689 98.0
CMS2_k127_4997369_31 cation transport ATPase K01533,K17686 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.4,3.6.3.54 0.000000000000000000001289 94.0
CMS2_k127_4997369_32 Protein of unknown function (DUF2933) - - - 0.0000000000000003087 82.0
CMS2_k127_4997369_33 Protein of unknown function (DUF2933) - - - 0.0000000000103 69.0
CMS2_k127_4997369_34 Cytochrome c - - - 0.000000001316 64.0
CMS2_k127_4997369_35 Protein of unknown function (DUF1573) - - - 0.000000002539 66.0
CMS2_k127_4997369_36 Cbb3-type cytochrome oxidase K00407 - - 0.000000209 54.0
CMS2_k127_4997369_37 - - - - 0.00003994 54.0
CMS2_k127_4997369_4 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 612.0
CMS2_k127_4997369_5 ABC transporter K01990,K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008678 466.0
CMS2_k127_4997369_6 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 406.0
CMS2_k127_4997369_7 COG0644 Dehydrogenases (flavoproteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 366.0
CMS2_k127_4997369_8 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 352.0
CMS2_k127_4997369_9 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 329.0
CMS2_k127_5119989_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1049.0
CMS2_k127_5119989_1 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032,K13892 - - 1.124e-291 910.0
CMS2_k127_5119989_10 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 398.0
CMS2_k127_5119989_11 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 372.0
CMS2_k127_5119989_12 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 361.0
CMS2_k127_5119989_13 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 346.0
CMS2_k127_5119989_14 mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 345.0
CMS2_k127_5119989_15 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 352.0
CMS2_k127_5119989_16 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 332.0
CMS2_k127_5119989_17 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 322.0
CMS2_k127_5119989_18 PFAM Taurine catabolism dioxygenase TauD TfdA K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 291.0
CMS2_k127_5119989_19 PFAM Acyl-CoA dehydrogenase type 2 K16047 - 1.14.14.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 295.0
CMS2_k127_5119989_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 5.043e-274 855.0
CMS2_k127_5119989_20 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 293.0
CMS2_k127_5119989_21 N-acetylmuramoyl-L-alanine amidase K01447,K11066 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002969 284.0
CMS2_k127_5119989_22 secretion protein HlyD K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001637 286.0
CMS2_k127_5119989_23 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001941 276.0
CMS2_k127_5119989_24 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002296 277.0
CMS2_k127_5119989_25 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000169 271.0
CMS2_k127_5119989_26 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005293 270.0
CMS2_k127_5119989_27 lactate metabolic process K00113 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000004402 249.0
CMS2_k127_5119989_28 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01856,K01860,K19802 - 5.1.1.20,5.5.1.1,5.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000002752 240.0
CMS2_k127_5119989_29 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000003085 231.0
CMS2_k127_5119989_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.101e-251 784.0
CMS2_k127_5119989_30 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000001438 187.0
CMS2_k127_5119989_31 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000007092 183.0
CMS2_k127_5119989_32 TspO/MBR family K05770 - - 0.000000000000000000000000000000000000000000001705 176.0
CMS2_k127_5119989_33 - - - - 0.00000000000000000000000000000000000000000000632 168.0
CMS2_k127_5119989_34 Alkaline phosphatase - - - 0.0000000000000000000000000000000000000119 166.0
CMS2_k127_5119989_35 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000002645 139.0
CMS2_k127_5119989_36 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000006973 130.0
CMS2_k127_5119989_38 Tellurite resistance protein TerB - - - 0.000000000000000000006643 98.0
CMS2_k127_5119989_39 YCII-related domain K09780 - - 0.0000000000000000000764 93.0
CMS2_k127_5119989_4 major facilitator superfamily K03446 - - 1.657e-210 665.0
CMS2_k127_5119989_40 COG2199 FOG GGDEF domain - - - 0.0000000000000002326 87.0
CMS2_k127_5119989_41 SMART Transport-associated and nodulation - - - 0.00004835 51.0
CMS2_k127_5119989_5 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 613.0
CMS2_k127_5119989_6 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 524.0
CMS2_k127_5119989_7 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 482.0
CMS2_k127_5119989_8 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 438.0
CMS2_k127_5119989_9 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 413.0
CMS2_k127_5202331_0 aconitate hydratase - - - 3.168e-313 976.0
CMS2_k127_5202331_1 Hydrolase CocE NonD family K06978 - - 9.416e-240 754.0
CMS2_k127_5202331_10 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004567 224.0
CMS2_k127_5202331_11 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000004497 224.0
CMS2_k127_5202331_12 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000003644 215.0
CMS2_k127_5202331_13 Catalyzes the conversion of maleate to fumarate K01799,K06033 - 4.1.1.76,5.2.1.1 0.0000000000000000000000000000000000000000000000000000004509 202.0
CMS2_k127_5202331_14 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000009323 191.0
CMS2_k127_5202331_15 membrane transporter protein K07090 - - 0.0000000000000000000000000000000002505 141.0
CMS2_k127_5202331_16 Succinylglutamate desuccinylase K06987 - - 0.000000000000000000004946 105.0
CMS2_k127_5202331_17 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000000001008 91.0
CMS2_k127_5202331_18 ABC transporter substrate-binding protein K22003 - 5.3.3.7 0.00000000000004009 82.0
CMS2_k127_5202331_2 Ferrous iron transport protein B K04759 - - 1.181e-225 718.0
CMS2_k127_5202331_3 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 535.0
CMS2_k127_5202331_4 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 433.0
CMS2_k127_5202331_5 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 387.0
CMS2_k127_5202331_6 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 376.0
CMS2_k127_5202331_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 342.0
CMS2_k127_5202331_8 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 348.0
CMS2_k127_5202331_9 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 320.0
CMS2_k127_5304848_0 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 568.0
CMS2_k127_5304848_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 357.0
CMS2_k127_5304848_10 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000957 198.0
CMS2_k127_5304848_11 - - - - 0.0000000000000000000000000000000000000000000003184 177.0
CMS2_k127_5304848_12 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000001003 178.0
CMS2_k127_5304848_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000003548 114.0
CMS2_k127_5304848_14 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0002035 46.0
CMS2_k127_5304848_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 358.0
CMS2_k127_5304848_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 340.0
CMS2_k127_5304848_4 FMN-dependent dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 334.0
CMS2_k127_5304848_5 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 324.0
CMS2_k127_5304848_6 proline dipeptidase activity K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 294.0
CMS2_k127_5304848_7 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 244.0
CMS2_k127_5304848_8 Thioesterase - - - 0.00000000000000000000000000000000000000000000000000000000005535 213.0
CMS2_k127_5304848_9 binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000005006 215.0
CMS2_k127_5321313_0 Belongs to the TPP enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 469.0
CMS2_k127_5321313_1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 452.0
CMS2_k127_5321313_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 412.0
CMS2_k127_5321313_3 PFAM amidohydrolase 2 K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 333.0
CMS2_k127_5321313_4 GntR family transcriptional regulator K15977 - - 0.00000000000000000000000000000000000000005361 154.0
CMS2_k127_5321313_5 - - - - 0.00000000000000000000000000004168 120.0
CMS2_k127_5321313_6 Cupin 2, conserved barrel K21700 - - 0.0000001598 52.0
CMS2_k127_5321313_7 YCII-related domain K09780 - - 0.0000004605 59.0
CMS2_k127_5321313_8 protein conserved in bacteria K09780 - - 0.000002045 57.0
CMS2_k127_5334887_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 7.257e-239 754.0
CMS2_k127_5334887_1 TonB dependent receptor K02014 - - 4.295e-229 731.0
CMS2_k127_5334887_2 PFAM glycosyl transferase family 9 K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 353.0
CMS2_k127_5334887_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 307.0
CMS2_k127_5334887_4 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008165 283.0
CMS2_k127_5334887_5 Methyltransferase domain - - - 0.00000000000000000007807 100.0
CMS2_k127_5360653_0 Strictosidine synthase K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 489.0
CMS2_k127_5360653_1 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009909 422.0
CMS2_k127_5360653_10 Protein of unknown function (DUF1059) - - - 0.0000002778 52.0
CMS2_k127_5360653_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 323.0
CMS2_k127_5360653_3 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000259 218.0
CMS2_k127_5360653_4 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000494 205.0
CMS2_k127_5360653_5 PFAM conserved - - - 0.00000000000000000000000000000000000000006711 161.0
CMS2_k127_5360653_6 rhamnose metabolic process - - - 0.000000000000000000000000000000001712 137.0
CMS2_k127_5360653_7 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000003869 123.0
CMS2_k127_5360653_8 Protein of unknown function (DUF1059) - - - 0.0000000000000000000000003117 105.0
CMS2_k127_5360653_9 plasmid maintenance K03496 - - 0.000000000000004369 81.0
CMS2_k127_5429859_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0 1017.0
CMS2_k127_5429859_1 AAA ATPase central domain protein K07478 - - 3.566e-195 622.0
CMS2_k127_5429859_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 598.0
CMS2_k127_5429859_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 506.0
CMS2_k127_5429859_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000005997 237.0
CMS2_k127_5429859_5 Transcriptional regulator crp fnr family K10914 - - 0.0000000000000000000000000000000000000000000000000000000000009738 218.0
CMS2_k127_5429859_6 FecR protein - - - 0.0000000000000000000000000000000000000007991 160.0
CMS2_k127_5429859_7 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000004619 57.0
CMS2_k127_5429859_9 Domain of unknown function (DUF4124) - - - 0.0001502 52.0
CMS2_k127_5517872_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 1.267e-239 747.0
CMS2_k127_5517872_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 9.892e-224 704.0
CMS2_k127_5517872_10 Amidohydrolase K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000001878 243.0
CMS2_k127_5517872_11 Beta-Ig-H3 fasciclin - - - 0.000000000000000000000000000000000000000000000000000003684 194.0
CMS2_k127_5517872_12 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000001048 188.0
CMS2_k127_5517872_13 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000004932 150.0
CMS2_k127_5517872_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000002045 141.0
CMS2_k127_5517872_15 D-galactarate dehydratase Altronate hydrolase K01685,K16846 - 4.2.1.7,4.4.1.24 0.0000000000000000000000000000002309 123.0
CMS2_k127_5517872_16 - - - - 0.00000000000000000000000001165 114.0
CMS2_k127_5517872_17 regulation of ryanodine-sensitive calcium-release channel activity - - - 0.0000000000000000000000001071 119.0
CMS2_k127_5517872_19 YCII-related domain K09780 - - 0.000000000000000000831 90.0
CMS2_k127_5517872_2 alanine symporter K03310 - - 8.22e-209 659.0
CMS2_k127_5517872_20 EamA-like transporter family - - - 0.00000003815 64.0
CMS2_k127_5517872_21 OsmC-like protein - - - 0.000001689 53.0
CMS2_k127_5517872_3 GMC oxidoreductase K00108 - 1.1.99.1 6.956e-196 624.0
CMS2_k127_5517872_4 decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 480.0
CMS2_k127_5517872_5 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 394.0
CMS2_k127_5517872_6 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 381.0
CMS2_k127_5517872_7 X-Pro dipeptidyl-peptidase domain protein K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 375.0
CMS2_k127_5517872_8 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 338.0
CMS2_k127_5517872_9 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 301.0
CMS2_k127_5520241_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 571.0
CMS2_k127_5520241_1 TRAP transporter, solute receptor (TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 406.0
CMS2_k127_5520241_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 302.0
CMS2_k127_5520241_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 293.0
CMS2_k127_5520241_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003035 277.0
CMS2_k127_5520241_5 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000001195 229.0
CMS2_k127_5520241_6 PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000001782 192.0
CMS2_k127_5520241_7 TRAP transporter, 4TM 12TM fusion protein - - - 0.000000000000000000000000000000000000000000000000296 181.0
CMS2_k127_5520241_8 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000349 131.0
CMS2_k127_5548959_0 membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 485.0
CMS2_k127_5548959_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 413.0
CMS2_k127_5548959_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000002404 213.0
CMS2_k127_5548959_3 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.00000000000000002243 83.0
CMS2_k127_5686926_0 Belongs to the CinA family - - - 1.388e-201 634.0
CMS2_k127_5686926_1 Thiamine pyrophosphate enzyme, central domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 604.0
CMS2_k127_5686926_10 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 291.0
CMS2_k127_5686926_11 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001535 285.0
CMS2_k127_5686926_12 Asp Glu Hydantoin racemase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003034 260.0
CMS2_k127_5686926_13 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006719 265.0
CMS2_k127_5686926_14 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002071 256.0
CMS2_k127_5686926_15 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004756 252.0
CMS2_k127_5686926_16 YCII-related domain K09780 - - 0.00000000000000000000000000000000000000000000000000000000000000001126 229.0
CMS2_k127_5686926_17 PFAM extracellular solute-binding protein family 1 K02020,K22003 - 5.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000033 224.0
CMS2_k127_5686926_18 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000002239 180.0
CMS2_k127_5686926_19 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000006182 162.0
CMS2_k127_5686926_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 520.0
CMS2_k127_5686926_20 MAPEG family - - - 0.00000000000000000000000000000000000000001857 158.0
CMS2_k127_5686926_21 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000000000000006118 154.0
CMS2_k127_5686926_22 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000181 150.0
CMS2_k127_5686926_23 - - - - 0.000000000000000000000000000000000000001872 153.0
CMS2_k127_5686926_24 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.000000000000000000000000000000000000003843 155.0
CMS2_k127_5686926_25 cytochrome - - - 0.00000000000000000000000000000000000007046 149.0
CMS2_k127_5686926_26 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000001039 129.0
CMS2_k127_5686926_27 Rhodanese-like domain - - - 0.000000000000000000001891 99.0
CMS2_k127_5686926_28 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation - - - 0.0000000000000001493 91.0
CMS2_k127_5686926_3 COG2951 Membrane-bound lytic murein transglycosylase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 473.0
CMS2_k127_5686926_30 helix_turn_helix, Lux Regulon - - - 0.000000000006809 69.0
CMS2_k127_5686926_4 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 455.0
CMS2_k127_5686926_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 436.0
CMS2_k127_5686926_6 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 436.0
CMS2_k127_5686926_7 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 387.0
CMS2_k127_5686926_8 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 306.0
CMS2_k127_5686926_9 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 302.0
CMS2_k127_5695880_0 formate hydrogenlyase subunit 3 multisubunit Na H antiporter, MnhD subunit K05568,K12137 - - 9.505e-261 814.0
CMS2_k127_5695880_1 Proton-conducting membrane transporter - - - 6.311e-212 677.0
CMS2_k127_5695880_10 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 415.0
CMS2_k127_5695880_11 Pfam Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 406.0
CMS2_k127_5695880_12 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 365.0
CMS2_k127_5695880_13 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 360.0
CMS2_k127_5695880_14 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 353.0
CMS2_k127_5695880_15 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 338.0
CMS2_k127_5695880_16 abc transporter, ATP-binding protein K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 335.0
CMS2_k127_5695880_17 ABC-type amino acid transport system permease component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 308.0
CMS2_k127_5695880_18 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 299.0
CMS2_k127_5695880_19 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001504 265.0
CMS2_k127_5695880_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 6.438e-198 625.0
CMS2_k127_5695880_20 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007967 256.0
CMS2_k127_5695880_21 MarC family integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
CMS2_k127_5695880_22 Na H antiporter, MnhB K05566 - - 0.00000000000000000000000000000000000000000000000000000000000000004865 226.0
CMS2_k127_5695880_23 COG1863 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.0000000000000000000000000000000000000000000000000000001432 199.0
CMS2_k127_5695880_24 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000004607 205.0
CMS2_k127_5695880_25 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.0000000000000000000000000000000000000000000000000000005179 203.0
CMS2_k127_5695880_26 Na H antiporter, MnhB K05566 - - 0.00000000000000000000000000000000000000000000000000001065 201.0
CMS2_k127_5695880_27 transcriptional - - - 0.00000000000000000000000000000000000000000000000000002962 194.0
CMS2_k127_5695880_28 L-2,4-diaminobutyric acid acetyltransferase K06718 - 2.3.1.178 0.000000000000000000000000000000000000000000000000000174 191.0
CMS2_k127_5695880_29 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000003185 180.0
CMS2_k127_5695880_3 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 616.0
CMS2_k127_5695880_30 COG1006 Multisubunit Na H antiporter, MnhC subunit K05567 - - 0.0000000000000000000000000000000000000000000002223 177.0
CMS2_k127_5695880_31 Phasin protein - - - 0.00000000000000000000000000000000000006769 149.0
CMS2_k127_5695880_32 monovalent cation:proton antiporter activity K05571 - - 0.0000000000000000000000000000000008188 138.0
CMS2_k127_5695880_33 Multiple resistance and pH regulation protein F K05570 - - 0.000000000000000000000000005187 121.0
CMS2_k127_5695880_34 - - - - 0.000000000000000000003869 96.0
CMS2_k127_5695880_35 - - - - 0.0000000001174 73.0
CMS2_k127_5695880_36 - - - - 0.00000001463 66.0
CMS2_k127_5695880_4 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 616.0
CMS2_k127_5695880_5 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 541.0
CMS2_k127_5695880_6 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 560.0
CMS2_k127_5695880_7 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 480.0
CMS2_k127_5695880_8 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 433.0
CMS2_k127_5695880_9 Ectoine hydroxylase K10674 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.11.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 413.0
CMS2_k127_5738540_0 PrpF protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 471.0
CMS2_k127_5738540_1 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 376.0
CMS2_k127_5738540_10 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001153 244.0
CMS2_k127_5738540_11 Putative molybdenum carrier - - - 0.000000000000000000000000000000000000000000000268 173.0
CMS2_k127_5738540_12 PFAM Hydantoinase oxoprolinase K01469 - 3.5.2.9 0.0000000000000000000000000000000004233 132.0
CMS2_k127_5738540_13 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.000000000000000000000000000000008063 128.0
CMS2_k127_5738540_2 Dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 368.0
CMS2_k127_5738540_3 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 337.0
CMS2_k127_5738540_4 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 318.0
CMS2_k127_5738540_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 305.0
CMS2_k127_5738540_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000104 286.0
CMS2_k127_5738540_7 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003009 281.0
CMS2_k127_5738540_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003251 282.0
CMS2_k127_5738540_9 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001962 266.0
CMS2_k127_5791541_0 Protein conserved in bacteria K07793 - - 2.62e-224 704.0
CMS2_k127_5791541_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.433e-194 612.0
CMS2_k127_5791541_10 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000177 246.0
CMS2_k127_5791541_11 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000003742 238.0
CMS2_k127_5791541_12 universal stress protein - - - 0.0000000000000000000000000000000000000003289 154.0
CMS2_k127_5791541_13 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000003145 139.0
CMS2_k127_5791541_14 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000004954 60.0
CMS2_k127_5791541_15 PFAM Anti sigma-E protein RseA K03597 - - 0.0008535 47.0
CMS2_k127_5791541_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 512.0
CMS2_k127_5791541_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 462.0
CMS2_k127_5791541_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 379.0
CMS2_k127_5791541_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 370.0
CMS2_k127_5791541_6 Capsule synthesis protein K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 316.0
CMS2_k127_5791541_7 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 311.0
CMS2_k127_5791541_8 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 300.0
CMS2_k127_5791541_9 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002007 286.0
CMS2_k127_5822415_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 2.435e-265 824.0
CMS2_k127_5822415_1 Cytochrome c bacterial - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 604.0
CMS2_k127_5822415_10 Histidine kinase - - - 0.000000001181 61.0
CMS2_k127_5822415_2 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 342.0
CMS2_k127_5822415_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 292.0
CMS2_k127_5822415_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001485 261.0
CMS2_k127_5822415_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000006634 190.0
CMS2_k127_5822415_6 GGDEF domain' - - - 0.0000000000000000000000000000000000000000000001374 184.0
CMS2_k127_5822415_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000002291 169.0
CMS2_k127_5822415_8 Transcriptional regulator - - - 0.000000000000000000000001946 104.0
CMS2_k127_5822415_9 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000002374 101.0
CMS2_k127_5867703_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 3.804e-317 981.0
CMS2_k127_5867703_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.396e-306 951.0
CMS2_k127_5867703_10 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 606.0
CMS2_k127_5867703_11 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 608.0
CMS2_k127_5867703_12 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 597.0
CMS2_k127_5867703_13 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 580.0
CMS2_k127_5867703_14 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 568.0
CMS2_k127_5867703_15 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 553.0
CMS2_k127_5867703_16 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 540.0
CMS2_k127_5867703_17 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 555.0
CMS2_k127_5867703_18 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 521.0
CMS2_k127_5867703_19 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 491.0
CMS2_k127_5867703_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.68e-265 835.0
CMS2_k127_5867703_20 PFAM Mur ligase middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 483.0
CMS2_k127_5867703_21 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 469.0
CMS2_k127_5867703_22 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 467.0
CMS2_k127_5867703_23 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 463.0
CMS2_k127_5867703_24 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 449.0
CMS2_k127_5867703_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 436.0
CMS2_k127_5867703_26 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 445.0
CMS2_k127_5867703_27 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 420.0
CMS2_k127_5867703_28 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 419.0
CMS2_k127_5867703_29 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 397.0
CMS2_k127_5867703_3 Transmembrane secretion effector - - - 4.673e-257 806.0
CMS2_k127_5867703_30 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 388.0
CMS2_k127_5867703_31 pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 404.0
CMS2_k127_5867703_32 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 372.0
CMS2_k127_5867703_33 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 354.0
CMS2_k127_5867703_34 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 345.0
CMS2_k127_5867703_35 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 344.0
CMS2_k127_5867703_36 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 339.0
CMS2_k127_5867703_37 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 338.0
CMS2_k127_5867703_38 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 303.0
CMS2_k127_5867703_39 response regulator receiver K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 304.0
CMS2_k127_5867703_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.749e-245 765.0
CMS2_k127_5867703_40 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 304.0
CMS2_k127_5867703_41 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 289.0
CMS2_k127_5867703_42 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003666 289.0
CMS2_k127_5867703_43 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 276.0
CMS2_k127_5867703_44 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004981 267.0
CMS2_k127_5867703_45 myo-inosose-2 dehydratase activity K00457,K06606 - 1.13.11.27,5.3.99.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000694 273.0
CMS2_k127_5867703_46 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000002926 247.0
CMS2_k127_5867703_47 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000000000000000009769 233.0
CMS2_k127_5867703_48 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000002246 229.0
CMS2_k127_5867703_49 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000003639 231.0
CMS2_k127_5867703_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.109e-244 761.0
CMS2_k127_5867703_50 Belongs to the mandelate racemase muconate lactonizing enzyme family K20023 - 4.2.1.156,4.2.1.42 0.0000000000000000000000000000000000000000000000000000000003787 220.0
CMS2_k127_5867703_51 - - - - 0.0000000000000000000000000000000000000000000000000000000004396 210.0
CMS2_k127_5867703_52 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000003788 189.0
CMS2_k127_5867703_53 alpha beta - - - 0.000000000000000000000000000000000000000007051 164.0
CMS2_k127_5867703_54 Colicin V production K03558 - - 0.00000000000000000000000000000000000000005207 160.0
CMS2_k127_5867703_55 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000004543 153.0
CMS2_k127_5867703_56 Macrocin-O-methyltransferase (TylF) K05303 - - 0.000000000000000000000000000000006293 138.0
CMS2_k127_5867703_57 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000004504 123.0
CMS2_k127_5867703_58 Sporulation related domain K03749 - - 0.00000000000000000000000000001387 125.0
CMS2_k127_5867703_59 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000001078 123.0
CMS2_k127_5867703_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 4.87e-221 689.0
CMS2_k127_5867703_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 3.008e-219 689.0
CMS2_k127_5867703_8 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 9.213e-206 645.0
CMS2_k127_5867703_9 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 4.572e-198 622.0
CMS2_k127_5887673_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 8.241e-249 777.0
CMS2_k127_5887673_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 5.238e-229 717.0
CMS2_k127_5887673_10 CoA-transferase family III K18289 - 2.8.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 511.0
CMS2_k127_5887673_11 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 504.0
CMS2_k127_5887673_12 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 498.0
CMS2_k127_5887673_13 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 377.0
CMS2_k127_5887673_14 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 368.0
CMS2_k127_5887673_15 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 362.0
CMS2_k127_5887673_16 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 345.0
CMS2_k127_5887673_17 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 334.0
CMS2_k127_5887673_18 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 325.0
CMS2_k127_5887673_19 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 306.0
CMS2_k127_5887673_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 5.37e-216 683.0
CMS2_k127_5887673_20 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 306.0
CMS2_k127_5887673_21 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 303.0
CMS2_k127_5887673_22 serine threonine protein kinase K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 306.0
CMS2_k127_5887673_23 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002705 267.0
CMS2_k127_5887673_24 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001015 267.0
CMS2_k127_5887673_25 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002114 274.0
CMS2_k127_5887673_26 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003843 270.0
CMS2_k127_5887673_27 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K21062 - 3.5.4.22,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000002077 264.0
CMS2_k127_5887673_28 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002506 262.0
CMS2_k127_5887673_29 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001326 256.0
CMS2_k127_5887673_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.043e-212 680.0
CMS2_k127_5887673_30 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000306 254.0
CMS2_k127_5887673_31 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008731 239.0
CMS2_k127_5887673_32 - K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000001498 224.0
CMS2_k127_5887673_33 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000001025 228.0
CMS2_k127_5887673_34 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000155 219.0
CMS2_k127_5887673_35 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000002185 220.0
CMS2_k127_5887673_36 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000001673 217.0
CMS2_k127_5887673_37 - K11477 - - 0.00000000000000000000000000000000000000000000000000000000001024 210.0
CMS2_k127_5887673_38 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000002043 194.0
CMS2_k127_5887673_39 HNH nucleases - - - 0.0000000000000000000000000000000000000000000009814 170.0
CMS2_k127_5887673_4 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.115e-206 649.0
CMS2_k127_5887673_40 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000000003148 170.0
CMS2_k127_5887673_41 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000436 171.0
CMS2_k127_5887673_42 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000007051 164.0
CMS2_k127_5887673_43 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000001942 143.0
CMS2_k127_5887673_44 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000000000003945 137.0
CMS2_k127_5887673_45 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000004034 128.0
CMS2_k127_5887673_46 GYD domain - - - 0.00000000000000000000000000006955 119.0
CMS2_k127_5887673_48 Putative prokaryotic signal transducing protein - - - 0.000000000000000001722 90.0
CMS2_k127_5887673_49 Protein of unknown function (DUF3012) - - - 0.00000000000000004452 85.0
CMS2_k127_5887673_5 Tripartite tricarboxylate transporter TctA family - - - 2.658e-195 620.0
CMS2_k127_5887673_50 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000002624 82.0
CMS2_k127_5887673_51 Cupin 2, conserved barrel domain protein K01810 - 5.3.1.9 0.0000008301 60.0
CMS2_k127_5887673_6 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 593.0
CMS2_k127_5887673_7 carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 560.0
CMS2_k127_5887673_8 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 560.0
CMS2_k127_5887673_9 transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 536.0
CMS2_k127_5892725_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 9.337e-313 968.0
CMS2_k127_5892725_1 Transglutaminase/protease-like homologues - - - 1.37e-261 826.0
CMS2_k127_5892725_10 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 517.0
CMS2_k127_5892725_11 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 390.0
CMS2_k127_5892725_12 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 379.0
CMS2_k127_5892725_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 370.0
CMS2_k127_5892725_14 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 341.0
CMS2_k127_5892725_15 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 332.0
CMS2_k127_5892725_16 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 317.0
CMS2_k127_5892725_17 Bacterial transglutaminase-like N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 316.0
CMS2_k127_5892725_18 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 314.0
CMS2_k127_5892725_19 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 306.0
CMS2_k127_5892725_2 HELICc2 K03722 - 3.6.4.12 1.708e-261 822.0
CMS2_k127_5892725_20 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 302.0
CMS2_k127_5892725_21 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 297.0
CMS2_k127_5892725_22 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000006474 271.0
CMS2_k127_5892725_23 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002231 244.0
CMS2_k127_5892725_24 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000414 247.0
CMS2_k127_5892725_25 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000875 242.0
CMS2_k127_5892725_26 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000000000000000000000000000003691 212.0
CMS2_k127_5892725_27 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000000000000000000000123 188.0
CMS2_k127_5892725_28 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000001641 157.0
CMS2_k127_5892725_29 NLP P60 protein - - - 0.000000000000000000000000000000000000001046 153.0
CMS2_k127_5892725_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 1.96e-260 826.0
CMS2_k127_5892725_30 transporter solute receptor, DctP family - - - 0.000000000000000000000000000000000009269 151.0
CMS2_k127_5892725_31 Glycine zipper 2TM domain - - - 0.000000000000000000000000000000001584 138.0
CMS2_k127_5892725_32 - - - - 0.00000000000000000000000000004075 130.0
CMS2_k127_5892725_33 Protein of unknown function (DUF3568) - - - 0.0000000000000000000000001636 111.0
CMS2_k127_5892725_34 SdpI/YhfL protein family - - - 0.000000000000000000000109 104.0
CMS2_k127_5892725_35 - - - - 0.0000005872 55.0
CMS2_k127_5892725_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 6.423e-220 692.0
CMS2_k127_5892725_5 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 3.038e-214 680.0
CMS2_k127_5892725_6 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 5.402e-211 672.0
CMS2_k127_5892725_7 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 1.772e-202 646.0
CMS2_k127_5892725_8 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 567.0
CMS2_k127_5892725_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 558.0
CMS2_k127_6115336_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 9.353e-229 721.0
CMS2_k127_6115336_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 496.0
CMS2_k127_6115336_2 L-lactate dehydrogenase K00101,K15054 - 1.1.2.3,1.1.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 453.0
CMS2_k127_6115336_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 400.0
CMS2_k127_6115336_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 389.0
CMS2_k127_6115336_5 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 406.0
CMS2_k127_6115336_6 acetylesterase activity K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000005888 239.0
CMS2_k127_6115336_7 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000001696 69.0
CMS2_k127_6120525_0 Methionine synthase K00548 - 2.1.1.13 0.0 1808.0
CMS2_k127_6120525_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 8.164e-237 740.0
CMS2_k127_6120525_10 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 465.0
CMS2_k127_6120525_11 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 439.0
CMS2_k127_6120525_12 exodeoxyribonuclease iii K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 413.0
CMS2_k127_6120525_13 drug resistance transporter K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 380.0
CMS2_k127_6120525_14 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 373.0
CMS2_k127_6120525_15 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 337.0
CMS2_k127_6120525_16 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 320.0
CMS2_k127_6120525_17 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 325.0
CMS2_k127_6120525_18 PFAM Methionine biosynthesis MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 283.0
CMS2_k127_6120525_19 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002288 286.0
CMS2_k127_6120525_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.354e-232 733.0
CMS2_k127_6120525_20 xylanase chitin deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007143 289.0
CMS2_k127_6120525_21 rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000000007301 209.0
CMS2_k127_6120525_22 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000000008208 205.0
CMS2_k127_6120525_23 CAAX amino Terminal protease family protein K07052 - - 0.0000000000000000000000000000000000000000000000000000000001143 214.0
CMS2_k127_6120525_24 Phosphotransferase system, mannose fructose-specific component IIA K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000000000003492 184.0
CMS2_k127_6120525_25 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000001659 171.0
CMS2_k127_6120525_26 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000006005 126.0
CMS2_k127_6120525_27 phosphocarrier protein HPR K11189 - - 0.0000000000000000000000000000007615 124.0
CMS2_k127_6120525_28 Psort location Cytoplasmic, score 8.96 K09806 - - 0.0000000000000000001845 90.0
CMS2_k127_6120525_29 - - - - 0.0000000000001091 79.0
CMS2_k127_6120525_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.899e-225 707.0
CMS2_k127_6120525_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 3.182e-210 664.0
CMS2_k127_6120525_5 Ammonium Transporter K03320 - - 6.782e-203 643.0
CMS2_k127_6120525_6 Rod shape-determining protein MreB K03569 - - 9.288e-194 607.0
CMS2_k127_6120525_7 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 591.0
CMS2_k127_6120525_8 Major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 552.0
CMS2_k127_6120525_9 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 486.0
CMS2_k127_6150515_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1206.0
CMS2_k127_6150515_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 295.0
CMS2_k127_6151082_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 526.0
CMS2_k127_6151082_1 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 496.0
CMS2_k127_6151082_10 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000000000001337 148.0
CMS2_k127_6151082_11 Cupin 2, conserved barrel domain protein K00450,K01628 - 1.13.11.4,4.1.2.17 0.000000000000000000000000000000000002331 146.0
CMS2_k127_6151082_12 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000001341 119.0
CMS2_k127_6151082_13 Thioesterase superfamily - - - 0.000000000000000000000009775 106.0
CMS2_k127_6151082_14 MlaD protein K02067 - - 0.000000000003094 68.0
CMS2_k127_6151082_2 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 487.0
CMS2_k127_6151082_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 396.0
CMS2_k127_6151082_4 hydroperoxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 376.0
CMS2_k127_6151082_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 339.0
CMS2_k127_6151082_6 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 312.0
CMS2_k127_6151082_7 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 298.0
CMS2_k127_6151082_8 HIT domain K02503 - - 0.000000000000000000000000000000000000000000000006515 175.0
CMS2_k127_6151082_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000002209 149.0
CMS2_k127_6458333_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1026.0
CMS2_k127_6458333_1 PFAM SNARE associated Golgi protein - - - 1.833e-231 741.0
CMS2_k127_6458333_2 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 456.0
CMS2_k127_6458333_3 Integral membrane protein TerC family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 322.0
CMS2_k127_6458333_4 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 307.0
CMS2_k127_6458333_5 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002554 252.0
CMS2_k127_6681381_0 Aconitase C-terminal domain K01681 - 4.2.1.3 1.664e-318 999.0
CMS2_k127_6681381_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K01652 - 2.2.1.6 2.671e-207 659.0
CMS2_k127_6681381_10 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 433.0
CMS2_k127_6681381_11 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 419.0
CMS2_k127_6681381_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 405.0
CMS2_k127_6681381_13 mandelate racemase muconate lactonizing K01856,K02549 - 4.2.1.113,5.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 361.0
CMS2_k127_6681381_14 alpha/beta hydrolase fold K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 353.0
CMS2_k127_6681381_15 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 323.0
CMS2_k127_6681381_16 Enoyl-CoA hydratase/isomerase K20765 - 3.7.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 302.0
CMS2_k127_6681381_17 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 299.0
CMS2_k127_6681381_18 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000789 290.0
CMS2_k127_6681381_19 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003906 282.0
CMS2_k127_6681381_2 MmgE/PrpD family - - - 5.921e-201 636.0
CMS2_k127_6681381_20 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001984 282.0
CMS2_k127_6681381_21 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003863 281.0
CMS2_k127_6681381_22 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000506 245.0
CMS2_k127_6681381_23 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000006886 205.0
CMS2_k127_6681381_24 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000003097 198.0
CMS2_k127_6681381_25 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000001145 173.0
CMS2_k127_6681381_26 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000003201 136.0
CMS2_k127_6681381_27 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000004044 101.0
CMS2_k127_6681381_3 MmgE/PrpD family - - - 8.976e-194 614.0
CMS2_k127_6681381_4 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 601.0
CMS2_k127_6681381_5 Conserved TM helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 552.0
CMS2_k127_6681381_6 gluconolactonase K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 525.0
CMS2_k127_6681381_7 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 444.0
CMS2_k127_6681381_8 Belongs to the PdxA family K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 443.0
CMS2_k127_6681381_9 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 430.0
CMS2_k127_6713841_0 response regulator K02481 - - 1.999e-219 695.0
CMS2_k127_6713841_1 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 574.0
CMS2_k127_6713841_2 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 336.0
CMS2_k127_6713841_3 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 295.0
CMS2_k127_6713841_4 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001796 285.0
CMS2_k127_6713841_5 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003583 250.0
CMS2_k127_6713841_6 response regulator K02481 - - 0.0000000000000000000000000000000000000001126 157.0
CMS2_k127_6747900_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 7.77e-301 929.0
CMS2_k127_6747900_1 ribonuclease II K01147 - 3.1.13.1 6.293e-215 683.0
CMS2_k127_6747900_2 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 380.0
CMS2_k127_6747900_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 306.0
CMS2_k127_6747900_4 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005185 287.0
CMS2_k127_6747900_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000001058 268.0
CMS2_k127_6747900_6 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000003036 254.0
CMS2_k127_6747900_7 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000001606 212.0
CMS2_k127_6747900_8 domain, Protein - - - 0.0000000000000000000000000000008411 127.0
CMS2_k127_6747900_9 - - - - 0.00000000003913 71.0
CMS2_k127_6764755_0 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 2.117e-251 783.0
CMS2_k127_6764755_1 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 3.775e-234 741.0
CMS2_k127_6764755_10 CHAT domain - - - 0.000000000000008557 84.0
CMS2_k127_6764755_11 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000002746 49.0
CMS2_k127_6764755_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 6.249e-214 676.0
CMS2_k127_6764755_3 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 462.0
CMS2_k127_6764755_4 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 469.0
CMS2_k127_6764755_5 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 292.0
CMS2_k127_6764755_6 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 282.0
CMS2_k127_6764755_7 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000001025 144.0
CMS2_k127_6764755_8 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000247 138.0
CMS2_k127_6764755_9 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000001022 97.0
CMS2_k127_6806433_0 major facilitator superfamily K03446 - - 1.155e-203 648.0
CMS2_k127_6806433_1 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 355.0
CMS2_k127_6806433_10 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000001218 210.0
CMS2_k127_6806433_11 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000000000000000000002404 171.0
CMS2_k127_6806433_12 Glyoxalase-like domain - - - 0.0000000000000000000005295 107.0
CMS2_k127_6806433_13 - - - - 0.00000000000008809 74.0
CMS2_k127_6806433_14 - - - - 0.000000005066 61.0
CMS2_k127_6806433_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 348.0
CMS2_k127_6806433_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 342.0
CMS2_k127_6806433_4 PFAM RES domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 305.0
CMS2_k127_6806433_5 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000013 294.0
CMS2_k127_6806433_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 291.0
CMS2_k127_6806433_7 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001276 248.0
CMS2_k127_6806433_8 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003155 235.0
CMS2_k127_6806433_9 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000001995 227.0
CMS2_k127_6821027_0 Tripartite tricarboxylate transporter TctA family - - - 7.235e-207 656.0
CMS2_k127_6821027_1 3-carboxy-cis,cis-muconate cycloisomerase K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 586.0
CMS2_k127_6821027_10 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000001135 167.0
CMS2_k127_6821027_11 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000003011 133.0
CMS2_k127_6821027_12 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000001273 126.0
CMS2_k127_6821027_2 succinate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 558.0
CMS2_k127_6821027_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 457.0
CMS2_k127_6821027_4 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 454.0
CMS2_k127_6821027_5 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 370.0
CMS2_k127_6821027_6 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 337.0
CMS2_k127_6821027_7 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008957 259.0
CMS2_k127_6821027_8 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028,K01039 - 2.8.3.12,2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000178 218.0
CMS2_k127_6821027_9 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000001929 186.0
CMS2_k127_6899466_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 1.329e-249 775.0
CMS2_k127_6899466_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.035e-200 636.0
CMS2_k127_6899466_10 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 393.0
CMS2_k127_6899466_11 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 390.0
CMS2_k127_6899466_12 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 394.0
CMS2_k127_6899466_13 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 380.0
CMS2_k127_6899466_14 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 361.0
CMS2_k127_6899466_15 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 342.0
CMS2_k127_6899466_16 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 316.0
CMS2_k127_6899466_17 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 309.0
CMS2_k127_6899466_18 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 306.0
CMS2_k127_6899466_19 Pfam Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005587 263.0
CMS2_k127_6899466_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.525e-196 617.0
CMS2_k127_6899466_20 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003733 260.0
CMS2_k127_6899466_21 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000001229 195.0
CMS2_k127_6899466_22 - - - - 0.00000000000000000000000000000000000000000000008264 177.0
CMS2_k127_6899466_23 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000000004546 159.0
CMS2_k127_6899466_24 CoA binding domain - - - 0.00000000000000000000000000000000000004608 147.0
CMS2_k127_6899466_25 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000002718 131.0
CMS2_k127_6899466_26 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000002595 113.0
CMS2_k127_6899466_27 Crp-like helix-turn-helix domain - - - 0.00000000000000000000007884 102.0
CMS2_k127_6899466_28 Glycine zipper 2TM domain K04062 - - 0.000000000000000000001032 96.0
CMS2_k127_6899466_29 Protein of unknown function (DUF3185) - - - 0.000000000000000001075 87.0
CMS2_k127_6899466_3 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 496.0
CMS2_k127_6899466_30 - - - - 0.000000000000009124 75.0
CMS2_k127_6899466_31 Protein of unknown function (DUF3096) - - - 0.00000000000002322 74.0
CMS2_k127_6899466_32 Glycine zipper 2TM domain - - - 0.000000000001429 73.0
CMS2_k127_6899466_33 Transglycosylase associated protein - - - 0.00000000001036 70.0
CMS2_k127_6899466_34 Entericidin EcnA/B family - - - 0.00000397 49.0
CMS2_k127_6899466_35 CsbD-like - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0002496 43.0
CMS2_k127_6899466_4 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 490.0
CMS2_k127_6899466_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 489.0
CMS2_k127_6899466_6 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 439.0
CMS2_k127_6899466_7 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 430.0
CMS2_k127_6899466_8 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 417.0
CMS2_k127_6899466_9 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 396.0
CMS2_k127_6964155_0 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 593.0
CMS2_k127_6964155_1 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 569.0
CMS2_k127_6964155_10 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 355.0
CMS2_k127_6964155_11 transport protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 356.0
CMS2_k127_6964155_12 TRAP-type C4-dicarboxylate transport system, large permease K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003474 271.0
CMS2_k127_6964155_13 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000008489 265.0
CMS2_k127_6964155_14 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002371 261.0
CMS2_k127_6964155_15 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005805 249.0
CMS2_k127_6964155_16 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000001707 249.0
CMS2_k127_6964155_17 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000001838 250.0
CMS2_k127_6964155_18 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001396 247.0
CMS2_k127_6964155_19 NADPH quinone - - - 0.0000000000000000000000000000000000000000000000000002198 198.0
CMS2_k127_6964155_2 COG1042 Acyl-CoA synthetase (NDP forming) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 577.0
CMS2_k127_6964155_20 SMP-30 Gluconolaconase K14274 - - 0.000000000000000000000000000000000000000000000000001912 193.0
CMS2_k127_6964155_21 - - - - 0.0000000000000000000000000000000000000000000004442 175.0
CMS2_k127_6964155_22 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000004584 166.0
CMS2_k127_6964155_23 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000461 138.0
CMS2_k127_6964155_24 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000002128 134.0
CMS2_k127_6964155_25 - - - - 0.000000000000000000001488 102.0
CMS2_k127_6964155_26 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00001211 54.0
CMS2_k127_6964155_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 543.0
CMS2_k127_6964155_4 4Fe-4S double cluster binding domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 514.0
CMS2_k127_6964155_5 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 477.0
CMS2_k127_6964155_6 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 464.0
CMS2_k127_6964155_7 L-lactate dehydrogenase K00101,K15054 - 1.1.2.3,1.1.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 450.0
CMS2_k127_6964155_8 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 413.0
CMS2_k127_6964155_9 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 399.0
CMS2_k127_7003774_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 554.0
CMS2_k127_7003774_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 426.0
CMS2_k127_7003774_10 Catalyzes the carbon skeleton rearrangement of L- glutamate to L-threo-3-methylaspartate ((2S,3S)-3- methylaspartate) K01846 - 5.4.99.1 0.000000000000000000000000000000000000000000000102 172.0
CMS2_k127_7003774_11 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000000000000008171 149.0
CMS2_k127_7003774_12 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000000000000000003081 114.0
CMS2_k127_7003774_13 AzlC protein - - - 0.00000000000000000000005998 102.0
CMS2_k127_7003774_14 Isochorismatase family - - - 0.0000000000000000000001135 106.0
CMS2_k127_7003774_15 - - - - 0.000000000000007679 76.0
CMS2_k127_7003774_2 TIGRFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 399.0
CMS2_k127_7003774_3 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 393.0
CMS2_k127_7003774_4 Catalyzes the carbon skeleton rearrangement of L- glutamate to L-threo-3-methylaspartate ((2S,3S)-3- methylaspartate) K19268 - 5.4.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008116 400.0
CMS2_k127_7003774_5 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 328.0
CMS2_k127_7003774_6 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 297.0
CMS2_k127_7003774_7 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 289.0
CMS2_k127_7003774_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001215 251.0
CMS2_k127_7003774_9 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000001741 204.0
CMS2_k127_7029478_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 7.096e-297 924.0
CMS2_k127_7029478_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 6.358e-233 738.0
CMS2_k127_7029478_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 311.0
CMS2_k127_7029478_11 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 302.0
CMS2_k127_7029478_12 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 288.0
CMS2_k127_7029478_13 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001684 263.0
CMS2_k127_7029478_14 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003753 268.0
CMS2_k127_7029478_15 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000004569 251.0
CMS2_k127_7029478_16 PFAM transport-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000003212 224.0
CMS2_k127_7029478_17 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000001557 221.0
CMS2_k127_7029478_18 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000007908 218.0
CMS2_k127_7029478_19 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000000000002628 211.0
CMS2_k127_7029478_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 536.0
CMS2_k127_7029478_20 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000001342 210.0
CMS2_k127_7029478_21 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000000000001671 186.0
CMS2_k127_7029478_22 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000001383 158.0
CMS2_k127_7029478_23 PFAM Sporulation domain protein - - - 0.00000000000000000000000000000002295 136.0
CMS2_k127_7029478_24 nucleic acid phosphodiester bond hydrolysis K07460 - - 0.0000000000000000000000000000001734 128.0
CMS2_k127_7029478_25 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000000000000001252 118.0
CMS2_k127_7029478_26 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000002739 59.0
CMS2_k127_7029478_3 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 515.0
CMS2_k127_7029478_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 398.0
CMS2_k127_7029478_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 396.0
CMS2_k127_7029478_6 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 361.0
CMS2_k127_7029478_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 327.0
CMS2_k127_7029478_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 311.0
CMS2_k127_7029478_9 Tetratricopeptide repeat K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 319.0
CMS2_k127_705587_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 6.088e-246 769.0
CMS2_k127_705587_1 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 9.468e-223 710.0
CMS2_k127_705587_2 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 8.601e-202 639.0
CMS2_k127_705587_3 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 491.0
CMS2_k127_705587_4 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 411.0
CMS2_k127_705587_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 341.0
CMS2_k127_705587_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 360.0
CMS2_k127_705587_7 electron transfer activity K03737,K05337 - 1.2.7.1 0.0008769 53.0
CMS2_k127_861106_0 Malic enzyme K00029 - 1.1.1.40 0.0 1080.0
CMS2_k127_861106_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.03e-222 697.0
CMS2_k127_861106_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 335.0
CMS2_k127_861106_11 response regulator K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 322.0
CMS2_k127_861106_12 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 326.0
CMS2_k127_861106_13 of murein hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 306.0
CMS2_k127_861106_14 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 304.0
CMS2_k127_861106_15 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 282.0
CMS2_k127_861106_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003031 280.0
CMS2_k127_861106_17 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000000000000000122 196.0
CMS2_k127_861106_18 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000002563 187.0
CMS2_k127_861106_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000002691 175.0
CMS2_k127_861106_2 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 604.0
CMS2_k127_861106_20 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000003361 168.0
CMS2_k127_861106_21 PFAM transcription elongation factor GreA GreB - - - 0.000000000000000000000000000000000000000001112 162.0
CMS2_k127_861106_22 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000001429 157.0
CMS2_k127_861106_23 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000004158 151.0
CMS2_k127_861106_24 aspartyl protease K06985 - - 0.0000000000000000000000000000000002197 147.0
CMS2_k127_861106_25 PFAM Lytic transglycosylase catalytic - - - 0.0000000000000000000000000000000004038 141.0
CMS2_k127_861106_26 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000003657 128.0
CMS2_k127_861106_27 effector of murein hydrolase LrgA K06518 - - 0.0000000000000000000000000000116 122.0
CMS2_k127_861106_28 - - - - 0.000000000000000000001678 96.0
CMS2_k127_861106_29 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000002914 90.0
CMS2_k127_861106_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 579.0
CMS2_k127_861106_30 - - - - 0.000000000000000004033 86.0
CMS2_k127_861106_31 OsmC-like protein - - - 0.00000001153 59.0
CMS2_k127_861106_33 - - - - 0.0000003625 52.0
CMS2_k127_861106_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 548.0
CMS2_k127_861106_5 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 520.0
CMS2_k127_861106_6 PFAM Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 509.0
CMS2_k127_861106_7 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 455.0
CMS2_k127_861106_8 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 443.0
CMS2_k127_861106_9 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 431.0
CMS2_k127_910404_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.0 1378.0
CMS2_k127_910404_1 AMP-binding enzyme C-terminal domain K00666 - - 2.23e-209 663.0
CMS2_k127_910404_10 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 372.0
CMS2_k127_910404_11 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 359.0
CMS2_k127_910404_12 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 365.0
CMS2_k127_910404_13 MauM NapG family ferredoxin-type protein K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 351.0
CMS2_k127_910404_14 PFAM amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 340.0
CMS2_k127_910404_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 332.0
CMS2_k127_910404_16 PFAM beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 336.0
CMS2_k127_910404_17 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 335.0
CMS2_k127_910404_18 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 325.0
CMS2_k127_910404_19 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 327.0
CMS2_k127_910404_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.196e-204 643.0
CMS2_k127_910404_20 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 325.0
CMS2_k127_910404_21 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 310.0
CMS2_k127_910404_22 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 294.0
CMS2_k127_910404_23 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 284.0
CMS2_k127_910404_24 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005362 278.0
CMS2_k127_910404_25 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002218 274.0
CMS2_k127_910404_26 Belongs to the helicase family. UvrD subfamily K10742 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000006008 268.0
CMS2_k127_910404_27 PFAM NapC NirT cytochrome c K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004689 265.0
CMS2_k127_910404_28 Nitrile hydratase, alpha chain K01721,K20807 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000007581 263.0
CMS2_k127_910404_29 Mate efflux family protein K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009911 279.0
CMS2_k127_910404_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 8.238e-204 641.0
CMS2_k127_910404_30 Asparaginase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002967 265.0
CMS2_k127_910404_31 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001098 259.0
CMS2_k127_910404_32 quinone binding K12057,K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000001573 252.0
CMS2_k127_910404_33 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003467 250.0
CMS2_k127_910404_34 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001775 244.0
CMS2_k127_910404_35 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002417 252.0
CMS2_k127_910404_36 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000001292 244.0
CMS2_k127_910404_37 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000008405 241.0
CMS2_k127_910404_38 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051,K15553 - - 0.00000000000000000000000000000000000000000000000000000000000000002671 242.0
CMS2_k127_910404_39 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000002126 216.0
CMS2_k127_910404_4 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 607.0
CMS2_k127_910404_40 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000005029 208.0
CMS2_k127_910404_41 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000005267 205.0
CMS2_k127_910404_42 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000003772 211.0
CMS2_k127_910404_43 Belongs to the UPF0255 family - - - 0.000000000000000000000000000000000000000000000000000001586 209.0
CMS2_k127_910404_44 extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000003582 212.0
CMS2_k127_910404_45 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000008309 199.0
CMS2_k127_910404_46 3'-5' exonuclease - - - 0.00000000000000000000000000000000000000000000000001994 185.0
CMS2_k127_910404_47 Pilin (bacterial filament) K02650 - - 0.00000000000000000000000000000000000000000000000005075 187.0
CMS2_k127_910404_48 KR domain - - - 0.0000000000000000000000000000000000000000000000003238 184.0
CMS2_k127_910404_49 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000007175 173.0
CMS2_k127_910404_5 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 574.0
CMS2_k127_910404_50 ferredoxin-type protein napF K02572 - - 0.000000000000000000000000000000000000000000001266 170.0
CMS2_k127_910404_51 PFAM Capsule synthesis protein, CapA K07282 - - 0.0000000000000000000000000000000000000000000157 175.0
CMS2_k127_910404_52 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000000007054 167.0
CMS2_k127_910404_53 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000001393 164.0
CMS2_k127_910404_54 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.0000000000000000000000000000000000000000003516 177.0
CMS2_k127_910404_55 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000006447 165.0
CMS2_k127_910404_56 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.0000000000000000000000000000000000000001347 152.0
CMS2_k127_910404_57 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.0000000000000000000000000000000000000001871 156.0
CMS2_k127_910404_58 - - - - 0.00000000000000000000000000000000002947 137.0
CMS2_k127_910404_59 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000000003847 141.0
CMS2_k127_910404_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 513.0
CMS2_k127_910404_60 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000007643 130.0
CMS2_k127_910404_61 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.00000000000000000000000000000696 127.0
CMS2_k127_910404_62 Binding-protein-dependent transport system inner membrane component K15554 - - 0.00000000000000000000000000005552 128.0
CMS2_k127_910404_63 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000002232 122.0
CMS2_k127_910404_64 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.0000000000000000000000001448 111.0
CMS2_k127_910404_65 DoxX K15977 - - 0.00000000000000000002988 95.0
CMS2_k127_910404_67 YCII-related domain K09780 - - 0.0000000000000000079 87.0
CMS2_k127_910404_68 SnoaL-like polyketide cyclase - - - 0.0000000000000003672 91.0
CMS2_k127_910404_69 PFAM NMT1 THI5 like K15553 - - 0.000000000000001797 88.0
CMS2_k127_910404_7 4Fe-4S binding domain K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 408.0
CMS2_k127_910404_70 Ester cyclase - - - 0.0000000002682 72.0
CMS2_k127_910404_71 Trap-type c4-dicarboxylate transport system, small permease component K11689,K21394 - - 0.000000001039 66.0
CMS2_k127_910404_73 - - - - 0.00000004434 59.0
CMS2_k127_910404_74 protein involved in formation of periplasmic nitrate reductase K02570 - - 0.00003431 51.0
CMS2_k127_910404_8 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 389.0
CMS2_k127_910404_9 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 378.0