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Overview

ID MAG00442
Name CMS2_bin.55
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family SG8-39
Genus JAOUFA01
Species
Assembly information
Completeness (%) 82.98
Contamination (%) 2.0
GC content (%) 68.0
N50 (bp) 17,060
Genome size (bp) 2,950,384

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2875

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1062251_0 protein conserved in bacteria K09800 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347 - 7.321e-207 692.0
CMS2_k127_1062251_1 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 466.0
CMS2_k127_1062251_2 POTRA domain TamA domain 1 K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 445.0
CMS2_k127_1062251_3 Type II/IV secretion system protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 423.0
CMS2_k127_1062251_4 transport, permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000004652 97.0
CMS2_k127_1082630_0 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000001756 242.0
CMS2_k127_1082630_1 Capsule assembly protein Wzi - - - 0.00000000000002051 86.0
CMS2_k127_1117510_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 571.0
CMS2_k127_1117510_1 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 458.0
CMS2_k127_1117510_10 TonB C terminal K03646 - - 0.000000000000000000000000000000000000000000002439 181.0
CMS2_k127_1117510_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000786 162.0
CMS2_k127_1117510_12 DGC domain - - - 0.00000000000000000000000000000000000000004403 158.0
CMS2_k127_1117510_13 - - - - 0.0000000000000000000000000000000000004401 150.0
CMS2_k127_1117510_14 Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000003801 139.0
CMS2_k127_1117510_15 KR domain - - - 0.00000000000000000000000000004541 121.0
CMS2_k127_1117510_16 - - - - 0.000000000000000000008224 106.0
CMS2_k127_1117510_17 heme oxygenase (decyclizing) activity - - - 0.00000000000000000146 89.0
CMS2_k127_1117510_18 - - - - 0.00007302 46.0
CMS2_k127_1117510_2 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 441.0
CMS2_k127_1117510_3 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 335.0
CMS2_k127_1117510_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 318.0
CMS2_k127_1117510_5 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 315.0
CMS2_k127_1117510_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 304.0
CMS2_k127_1117510_7 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000004802 203.0
CMS2_k127_1117510_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000001927 198.0
CMS2_k127_1117510_9 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000004271 173.0
CMS2_k127_1132954_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.257e-300 953.0
CMS2_k127_1132954_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 548.0
CMS2_k127_1132954_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000001986 70.0
CMS2_k127_1132954_11 beta-lactamase activity K07126 - - 0.0000009582 61.0
CMS2_k127_1132954_12 cytochrome c K00406 - - 0.000791 51.0
CMS2_k127_1132954_2 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 497.0
CMS2_k127_1132954_3 Catechol dioxygenase N terminus K03381 - 1.13.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 467.0
CMS2_k127_1132954_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 396.0
CMS2_k127_1132954_5 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 340.0
CMS2_k127_1132954_6 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 308.0
CMS2_k127_1132954_7 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004461 276.0
CMS2_k127_1132954_8 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000001484 110.0
CMS2_k127_1132954_9 - - - - 0.00000000000000000006294 94.0
CMS2_k127_1152239_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1632.0
CMS2_k127_1152239_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000001334 100.0
CMS2_k127_1160311_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.756e-225 712.0
CMS2_k127_1160311_1 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 1.514e-215 674.0
CMS2_k127_1160311_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000004932 223.0
CMS2_k127_1160311_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000001084 146.0
CMS2_k127_1160311_2 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 4.782e-194 612.0
CMS2_k127_1160311_3 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 552.0
CMS2_k127_1160311_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 556.0
CMS2_k127_1160311_5 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 544.0
CMS2_k127_1160311_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 535.0
CMS2_k127_1160311_7 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 489.0
CMS2_k127_1160311_8 Enoyl-(Acyl carrier protein) reductase K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 391.0
CMS2_k127_1160311_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000008031 243.0
CMS2_k127_1193861_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 1.702e-204 647.0
CMS2_k127_1193861_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 437.0
CMS2_k127_1193861_2 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 401.0
CMS2_k127_1193861_3 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 356.0
CMS2_k127_1193861_4 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 349.0
CMS2_k127_1193861_5 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 289.0
CMS2_k127_1193861_6 protein conserved in archaea - - - 0.0000000000000000000000000005343 128.0
CMS2_k127_1194069_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 7.046e-196 620.0
CMS2_k127_1194069_2 - - - - 0.0000000001029 67.0
CMS2_k127_1240539_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1088.0
CMS2_k127_1240539_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 432.0
CMS2_k127_1240539_2 Bacterial transcriptional repressor C-terminal K09017 - - 0.00000000000000000000000000000000000000000000000000000000000002859 221.0
CMS2_k127_1240539_3 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000116 215.0
CMS2_k127_1240539_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000001542 106.0
CMS2_k127_1281904_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1688.0
CMS2_k127_1281904_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1064.0
CMS2_k127_1281904_10 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 505.0
CMS2_k127_1281904_11 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 469.0
CMS2_k127_1281904_12 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 457.0
CMS2_k127_1281904_13 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 462.0
CMS2_k127_1281904_14 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 425.0
CMS2_k127_1281904_15 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 344.0
CMS2_k127_1281904_16 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 333.0
CMS2_k127_1281904_17 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 317.0
CMS2_k127_1281904_18 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 290.0
CMS2_k127_1281904_19 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000711 241.0
CMS2_k127_1281904_2 Heat shock 70 kDa protein K04043 - - 0.0 1023.0
CMS2_k127_1281904_20 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001193 244.0
CMS2_k127_1281904_21 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000002372 232.0
CMS2_k127_1281904_22 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000285 235.0
CMS2_k127_1281904_23 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000002122 224.0
CMS2_k127_1281904_24 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000005524 186.0
CMS2_k127_1281904_25 GrpE K03687 - - 0.000000000000000000000000000000000000000000000005519 178.0
CMS2_k127_1281904_26 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000000000003983 154.0
CMS2_k127_1281904_27 PFAM Colicin V production protein K03558 - - 0.000000000000000000000000000000000005943 143.0
CMS2_k127_1281904_28 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000004471 118.0
CMS2_k127_1281904_29 RNA-binding protein containing KH domain possibly ribosomal protein - - - 0.0000000000000000000000007601 109.0
CMS2_k127_1281904_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.221e-245 766.0
CMS2_k127_1281904_30 Sporulation related domain K03749 - - 0.000000000000000000000005773 109.0
CMS2_k127_1281904_31 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000002065 94.0
CMS2_k127_1281904_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 9.598e-216 677.0
CMS2_k127_1281904_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 594.0
CMS2_k127_1281904_6 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 563.0
CMS2_k127_1281904_7 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 567.0
CMS2_k127_1281904_8 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 520.0
CMS2_k127_1281904_9 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 503.0
CMS2_k127_1303023_0 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 589.0
CMS2_k127_1303023_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 571.0
CMS2_k127_1303023_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003359 275.0
CMS2_k127_1303023_11 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000003246 229.0
CMS2_k127_1303023_12 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000005 220.0
CMS2_k127_1303023_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000003268 180.0
CMS2_k127_1303023_14 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000004057 140.0
CMS2_k127_1303023_15 proteolysis - - - 0.00000000000000000000000000002515 131.0
CMS2_k127_1303023_16 Protein of unknown function (DUF2798) - - - 0.00000000004492 69.0
CMS2_k127_1303023_17 Cupin domain - - - 0.00000005617 56.0
CMS2_k127_1303023_18 mandelate racemase muconate lactonizing - - - 0.00005811 52.0
CMS2_k127_1303023_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 526.0
CMS2_k127_1303023_3 Protein of unknown function (DUF3422) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 420.0
CMS2_k127_1303023_4 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 363.0
CMS2_k127_1303023_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04098 - 1.13.11.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 343.0
CMS2_k127_1303023_6 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 323.0
CMS2_k127_1303023_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 323.0
CMS2_k127_1303023_8 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 314.0
CMS2_k127_1303023_9 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 320.0
CMS2_k127_130715_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.331e-201 641.0
CMS2_k127_130715_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 557.0
CMS2_k127_130715_2 PFAM FAD linked oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 531.0
CMS2_k127_130715_3 Aminotransferase class I and II K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 393.0
CMS2_k127_130715_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 319.0
CMS2_k127_130715_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005798 274.0
CMS2_k127_130715_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000007103 184.0
CMS2_k127_130715_7 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000003084 178.0
CMS2_k127_130715_8 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000005884 154.0
CMS2_k127_130715_9 Major Facilitator Superfamily - - - 0.00000000000000000000000001091 125.0
CMS2_k127_1319175_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 2.177e-203 653.0
CMS2_k127_1319175_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 352.0
CMS2_k127_1319175_2 M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000006234 211.0
CMS2_k127_1352710_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 6.586e-276 857.0
CMS2_k127_1352710_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.163e-203 642.0
CMS2_k127_1352710_10 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 291.0
CMS2_k127_1352710_11 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001394 286.0
CMS2_k127_1352710_12 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001772 273.0
CMS2_k127_1352710_13 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006072 259.0
CMS2_k127_1352710_14 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000001078 243.0
CMS2_k127_1352710_15 reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004032 233.0
CMS2_k127_1352710_16 CAAX protease self-immunity K07052 - - 0.000005545 57.0
CMS2_k127_1352710_2 ABC-type branched-chain amino acid transport systems periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 579.0
CMS2_k127_1352710_3 glycosyl transferase group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 546.0
CMS2_k127_1352710_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 486.0
CMS2_k127_1352710_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 442.0
CMS2_k127_1352710_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005838 376.0
CMS2_k127_1352710_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 385.0
CMS2_k127_1352710_8 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 369.0
CMS2_k127_1352710_9 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 346.0
CMS2_k127_1368690_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1176.0
CMS2_k127_1368690_1 amino acid - - - 3.635e-250 799.0
CMS2_k127_1368690_2 Chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 496.0
CMS2_k127_1368690_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 388.0
CMS2_k127_1368690_4 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 353.0
CMS2_k127_1368690_5 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006037 244.0
CMS2_k127_1368690_6 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.00000000000000000000000000000000000000000000000002157 197.0
CMS2_k127_1368690_7 Redoxin family - - - 0.0000000000000000000000000000000000000000002907 164.0
CMS2_k127_1368690_8 Protein of unknown function (DUF2782) - - - 0.0000000000000001511 83.0
CMS2_k127_1368690_9 - - - - 0.000000000005232 70.0
CMS2_k127_1390963_0 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 553.0
CMS2_k127_1390963_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 469.0
CMS2_k127_1390963_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 439.0
CMS2_k127_1390963_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001892 281.0
CMS2_k127_1390963_4 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002456 269.0
CMS2_k127_1390963_5 MaoC like domain K18290 - 4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000009864 216.0
CMS2_k127_1390963_6 PFAM diacylglycerol kinase catalytic region - - - 0.00000000001076 70.0
CMS2_k127_1424325_0 general secretion pathway protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000002243 235.0
CMS2_k127_1424325_1 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000949 209.0
CMS2_k127_1424325_2 General secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000007177 188.0
CMS2_k127_1424325_3 General secretion pathway protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000000000000000000000000005984 125.0
CMS2_k127_1424325_4 Type II secretion system (T2SS), protein I K02458 - - 0.000000000000000001043 94.0
CMS2_k127_1424325_5 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.00000000000000002217 91.0
CMS2_k127_1424325_6 general secretion pathway protein K02457 - - 0.00000000000009568 82.0
CMS2_k127_1434597_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002081 251.0
CMS2_k127_1434597_1 Thioesterase superfamily - - - 0.0000000000000000000000000000113 133.0
CMS2_k127_1434597_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000001975 132.0
CMS2_k127_1436184_0 Beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 455.0
CMS2_k127_1436184_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 360.0
CMS2_k127_1436184_2 Hsp33 protein K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000662 269.0
CMS2_k127_144095_0 CoA-binding domain protein K09181 - - 0.0 1139.0
CMS2_k127_144095_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.499e-226 714.0
CMS2_k127_144095_10 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000002634 127.0
CMS2_k127_144095_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 443.0
CMS2_k127_144095_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 381.0
CMS2_k127_144095_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 377.0
CMS2_k127_144095_5 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 296.0
CMS2_k127_144095_6 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008475 279.0
CMS2_k127_144095_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002338 255.0
CMS2_k127_144095_8 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000000000000000001112 238.0
CMS2_k127_144095_9 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000001568 230.0
CMS2_k127_1445506_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 519.0
CMS2_k127_1445506_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 413.0
CMS2_k127_144800_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1050.0
CMS2_k127_144800_1 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 518.0
CMS2_k127_144800_10 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000002752 164.0
CMS2_k127_144800_11 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000009205 151.0
CMS2_k127_144800_2 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 372.0
CMS2_k127_144800_3 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 360.0
CMS2_k127_144800_4 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 362.0
CMS2_k127_144800_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 299.0
CMS2_k127_144800_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 290.0
CMS2_k127_144800_7 Dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002219 277.0
CMS2_k127_144800_8 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000729 228.0
CMS2_k127_144800_9 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000003169 166.0
CMS2_k127_1460088_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 559.0
CMS2_k127_1460088_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 435.0
CMS2_k127_1460088_2 Amidohydrolase K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 357.0
CMS2_k127_1460088_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000001911 136.0
CMS2_k127_1469710_0 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 548.0
CMS2_k127_1469710_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 349.0
CMS2_k127_1469710_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 339.0
CMS2_k127_1469710_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001073 276.0
CMS2_k127_1469710_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000478 266.0
CMS2_k127_1469710_5 Glycosyltransferase 36 associated - - - 0.0000000000000000001012 90.0
CMS2_k127_1477624_0 Amidohydrolase K10220 - 4.2.1.83 8.395e-210 654.0
CMS2_k127_1477624_1 Receptor family ligand binding region K01999 - - 4.066e-200 629.0
CMS2_k127_1477624_10 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 355.0
CMS2_k127_1477624_11 SMART ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 346.0
CMS2_k127_1477624_12 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 305.0
CMS2_k127_1477624_13 Protocatechuate 4,5-dioxygenase K04100 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000004858 238.0
CMS2_k127_1477624_14 Ketosteroid isomerase-related protein - - - 0.00000000000000000000000000000000000000000000000000000009924 201.0
CMS2_k127_1477624_15 Aldolase/RraA K02553,K10218 - 4.1.3.17 0.000000000003997 70.0
CMS2_k127_1477624_16 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.00000001195 56.0
CMS2_k127_1477624_17 histidine kinase A domain protein - - - 0.0000000262 63.0
CMS2_k127_1477624_18 electron transfer activity K03737,K05337 - 1.2.7.1 0.0002066 55.0
CMS2_k127_1477624_19 SPFH domain-Band 7 family - - - 0.0009338 49.0
CMS2_k127_1477624_2 PrpF protein K16514 - 5.3.2.8 1.091e-194 614.0
CMS2_k127_1477624_3 Amidohydrolase K10221 - 3.1.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 585.0
CMS2_k127_1477624_4 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 543.0
CMS2_k127_1477624_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 494.0
CMS2_k127_1477624_6 deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 481.0
CMS2_k127_1477624_7 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 439.0
CMS2_k127_1477624_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 337.0
CMS2_k127_1477624_9 LysR substrate binding domain K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 338.0
CMS2_k127_1489349_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.235e-280 881.0
CMS2_k127_1489349_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.064e-234 744.0
CMS2_k127_1489349_10 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000187 191.0
CMS2_k127_1489349_11 Protein of unknown function (DUF1643) - - - 0.000000000000000000000000000000000000000000000000003489 188.0
CMS2_k127_1489349_12 NUDIX domain - - - 0.0000000000000000000000000000000000000000000006771 169.0
CMS2_k127_1489349_13 peptide chain release factor K15034 - - 0.000000000000000000000000000000000000000000001391 169.0
CMS2_k127_1489349_14 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000001271 149.0
CMS2_k127_1489349_15 PFAM multicopper oxidase type 2 - - - 0.00000000000000000000000000001616 117.0
CMS2_k127_1489349_16 PIN domain - - - 0.000000000000000000000000000638 118.0
CMS2_k127_1489349_17 - - - - 0.0000000000000000002693 101.0
CMS2_k127_1489349_2 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 539.0
CMS2_k127_1489349_3 helicase superfamily c-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 503.0
CMS2_k127_1489349_4 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 494.0
CMS2_k127_1489349_5 Benzoate membrane transport protein K05782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 490.0
CMS2_k127_1489349_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 377.0
CMS2_k127_1489349_7 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001631 302.0
CMS2_k127_1489349_8 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000004339 233.0
CMS2_k127_1489349_9 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000009176 202.0
CMS2_k127_153066_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 595.0
CMS2_k127_153066_1 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 514.0
CMS2_k127_153066_10 - - - - 0.00000000000000000000000000000000002661 139.0
CMS2_k127_153066_11 - - - - 0.00000000000000000000001685 104.0
CMS2_k127_153066_12 - - - - 0.00000000000000000000002845 102.0
CMS2_k127_153066_13 GMP synthase (glutamine-hydrolyzing) activity - - - 0.00000000000000000000007935 99.0
CMS2_k127_153066_14 involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000005641 76.0
CMS2_k127_153066_15 General Secretory Pathway K02463 - - 0.0000000001916 73.0
CMS2_k127_153066_16 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.000001551 57.0
CMS2_k127_153066_2 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 486.0
CMS2_k127_153066_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 414.0
CMS2_k127_153066_4 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 417.0
CMS2_k127_153066_5 Permeases of the drug metabolite transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 337.0
CMS2_k127_153066_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 326.0
CMS2_k127_153066_7 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 314.0
CMS2_k127_153066_8 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000000003897 210.0
CMS2_k127_153066_9 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000000000001436 170.0
CMS2_k127_1587387_0 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1081.0
CMS2_k127_1587387_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 1.274e-267 834.0
CMS2_k127_1587387_10 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000000000000000000001292 207.0
CMS2_k127_1587387_11 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000007838 192.0
CMS2_k127_1587387_12 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000103 166.0
CMS2_k127_1587387_13 Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000004608 130.0
CMS2_k127_1587387_14 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000007572 99.0
CMS2_k127_1587387_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000003022 63.0
CMS2_k127_1587387_2 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 8.357e-215 674.0
CMS2_k127_1587387_3 PFAM von Willebrand factor type A K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 463.0
CMS2_k127_1587387_4 peptidase m48, ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 441.0
CMS2_k127_1587387_5 CbbQ/NirQ/NorQ C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 385.0
CMS2_k127_1587387_6 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 320.0
CMS2_k127_1587387_7 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 315.0
CMS2_k127_1587387_8 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004895 263.0
CMS2_k127_1587387_9 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001457 239.0
CMS2_k127_1628262_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1157.0
CMS2_k127_1628262_1 pilus assembly protein tip-associated adhesin K02674 - - 1.985e-293 958.0
CMS2_k127_1628262_10 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 420.0
CMS2_k127_1628262_11 transport system, periplasmic component K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 406.0
CMS2_k127_1628262_12 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 375.0
CMS2_k127_1628262_13 heptosyltransferase II K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 347.0
CMS2_k127_1628262_14 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 305.0
CMS2_k127_1628262_15 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006788 274.0
CMS2_k127_1628262_16 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000211 233.0
CMS2_k127_1628262_17 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000004667 183.0
CMS2_k127_1628262_18 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000008966 182.0
CMS2_k127_1628262_19 Type II transport protein GspH K08084 - - 0.0000000000000000000000000000000000000000009503 171.0
CMS2_k127_1628262_2 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 4.279e-208 671.0
CMS2_k127_1628262_20 General secretion pathway protein K02459,K02672,K02680 - - 0.000000000000000000000000000000000000001244 169.0
CMS2_k127_1628262_21 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.00000000000000000000000000000000000004246 165.0
CMS2_k127_1628262_22 SnoaL-like domain - - - 0.0000000000000000000000000000000000002057 149.0
CMS2_k127_1628262_23 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000002478 152.0
CMS2_k127_1628262_24 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.0000000000000000000000000000000005363 135.0
CMS2_k127_1628262_25 Tfp pilus assembly protein K02655 - - 0.0000000000000000000000000000000005396 139.0
CMS2_k127_1628262_27 - - - - 0.000000000000000000000000002842 113.0
CMS2_k127_1628262_28 type IV pilus modification protein PilV K02671 - - 0.000000000000000000000000452 109.0
CMS2_k127_1628262_29 Pilus assembly protein PilX - - - 0.0000000000000000000006304 111.0
CMS2_k127_1628262_3 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 576.0
CMS2_k127_1628262_30 Zinc-finger domain - - - 0.000000000000000000004349 95.0
CMS2_k127_1628262_31 LuxR family - - - 0.00000000000000000001793 96.0
CMS2_k127_1628262_32 - - - - 0.0000000007514 67.0
CMS2_k127_1628262_33 - - - - 0.00002568 49.0
CMS2_k127_1628262_4 PFAM extracellular solute-binding protein family 1 K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 537.0
CMS2_k127_1628262_5 transport system, periplasmic component K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 516.0
CMS2_k127_1628262_6 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 519.0
CMS2_k127_1628262_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 466.0
CMS2_k127_1628262_8 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 465.0
CMS2_k127_1628262_9 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 422.0
CMS2_k127_1687070_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1244.0
CMS2_k127_1687070_1 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000003461 261.0
CMS2_k127_1687070_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000225 168.0
CMS2_k127_1687070_3 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000000000000001587 160.0
CMS2_k127_1687070_4 Outer membrane efflux protein K12340 - - 0.0008996 43.0
CMS2_k127_1687073_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1472.0
CMS2_k127_1687073_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000007925 78.0
CMS2_k127_1695010_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 8.427e-217 699.0
CMS2_k127_1695010_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 593.0
CMS2_k127_1695010_2 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 599.0
CMS2_k127_1695010_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 574.0
CMS2_k127_1695010_4 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000002043 227.0
CMS2_k127_1695010_5 Universal stress protein family - - - 0.0000000000000000000000000000000000000000001108 163.0
CMS2_k127_1695010_7 radical SAM domain protein K04070 - 1.97.1.4 0.000006674 50.0
CMS2_k127_1755373_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 3.436e-292 913.0
CMS2_k127_1755373_1 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 2.37e-215 687.0
CMS2_k127_1755373_10 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 418.0
CMS2_k127_1755373_11 5'-nucleotidase K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 415.0
CMS2_k127_1755373_12 Lipopolysaccharide export system ATP-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 372.0
CMS2_k127_1755373_13 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 367.0
CMS2_k127_1755373_14 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 338.0
CMS2_k127_1755373_15 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 345.0
CMS2_k127_1755373_16 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 318.0
CMS2_k127_1755373_17 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 316.0
CMS2_k127_1755373_18 Putative methyltransferase K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 309.0
CMS2_k127_1755373_19 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 297.0
CMS2_k127_1755373_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 523.0
CMS2_k127_1755373_20 Stress-induced protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000011 290.0
CMS2_k127_1755373_21 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004016 288.0
CMS2_k127_1755373_22 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000006956 264.0
CMS2_k127_1755373_23 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000008193 246.0
CMS2_k127_1755373_24 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000001044 240.0
CMS2_k127_1755373_26 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.0000000000000000000000000000000000000000000000000000000000009078 217.0
CMS2_k127_1755373_27 peptidase S16 K07157 - - 0.0000000000000000000000000000000000000000000000000000000004321 207.0
CMS2_k127_1755373_28 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000007674 192.0
CMS2_k127_1755373_3 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 486.0
CMS2_k127_1755373_30 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000001298 182.0
CMS2_k127_1755373_31 sigma 54 modulation protein K05808 - - 0.00000000000000000000000000000000000252 142.0
CMS2_k127_1755373_32 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000002934 127.0
CMS2_k127_1755373_33 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000001101 130.0
CMS2_k127_1755373_34 protein conserved in bacteria K11719 - - 0.00000000000000000000000000002623 126.0
CMS2_k127_1755373_35 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000002375 103.0
CMS2_k127_1755373_36 ThiS family K03154 - - 0.00000000000000000001508 93.0
CMS2_k127_1755373_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 482.0
CMS2_k127_1755373_5 Trypsin K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 482.0
CMS2_k127_1755373_6 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 496.0
CMS2_k127_1755373_7 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 455.0
CMS2_k127_1755373_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 430.0
CMS2_k127_1755373_9 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 445.0
CMS2_k127_176298_0 Ammonium Transporter Family K03320,K06580 - - 2.888e-206 651.0
CMS2_k127_176298_1 AMP-binding enzyme K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 595.0
CMS2_k127_176298_10 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 322.0
CMS2_k127_176298_11 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 307.0
CMS2_k127_176298_12 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004893 278.0
CMS2_k127_176298_13 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001596 277.0
CMS2_k127_176298_14 plastoquinol--plastocyanin reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000309 260.0
CMS2_k127_176298_15 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007844 263.0
CMS2_k127_176298_16 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000006303 226.0
CMS2_k127_176298_17 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000001267 219.0
CMS2_k127_176298_18 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000000001238 183.0
CMS2_k127_176298_19 Cytochrome c - - - 0.000000000000000000000000000000000000001004 150.0
CMS2_k127_176298_2 VWA domain containing CoxE-like protein K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 559.0
CMS2_k127_176298_20 Transcriptional regulator K03724 - - 0.0000000000000000000000000000000000000102 151.0
CMS2_k127_176298_21 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000004764 119.0
CMS2_k127_176298_22 cytochrome - - - 0.0000000000000000000004091 105.0
CMS2_k127_176298_23 OmpA-like transmembrane domain - - - 0.0000000000000000001019 98.0
CMS2_k127_176298_3 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 487.0
CMS2_k127_176298_4 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 471.0
CMS2_k127_176298_5 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 422.0
CMS2_k127_176298_6 Lysophospholipase - GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 415.0
CMS2_k127_176298_7 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 354.0
CMS2_k127_176298_8 VWA-like domain (DUF2201) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 357.0
CMS2_k127_176298_9 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 337.0
CMS2_k127_1763756_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 9.195e-212 673.0
CMS2_k127_1763756_1 General Secretion Pathway protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 592.0
CMS2_k127_1763756_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000008323 145.0
CMS2_k127_1763756_3 General secretion pathway protein C K02452 - - 0.0000000000000000000000000001998 126.0
CMS2_k127_1763756_4 General secretion pathway protein F K02455 - - 0.000000000001243 70.0
CMS2_k127_1794131_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 3.072e-255 810.0
CMS2_k127_1794131_1 Isocitrate lyase K01637 - 4.1.3.1 1.914e-226 709.0
CMS2_k127_1794131_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008478 474.0
CMS2_k127_1794131_3 shape-determining protein K03571 - - 0.000000000000000000000000000000000000000003168 162.0
CMS2_k127_181559_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 6.708e-243 762.0
CMS2_k127_181559_1 RESPONSE REGULATOR receiver K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 495.0
CMS2_k127_181559_10 VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003494 275.0
CMS2_k127_181559_11 ATPase activity, coupled to transmembrane movement of substances - - - 0.000000000000000000000000000000000000000000000000000000000000000000002602 257.0
CMS2_k127_181559_12 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000001684 218.0
CMS2_k127_181559_13 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.000000000000000000000000000000000000000000000000000000001761 207.0
CMS2_k127_181559_14 - - - - 0.000000000000000000000000000000000000000000000000000000002314 216.0
CMS2_k127_181559_15 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000001512 179.0
CMS2_k127_181559_16 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000001092 120.0
CMS2_k127_181559_17 transporter antisigma-factor antagonist STAS K07122 - - 0.000000000001112 78.0
CMS2_k127_181559_2 type II secretion system protein K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 478.0
CMS2_k127_181559_3 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 481.0
CMS2_k127_181559_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 432.0
CMS2_k127_181559_5 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 417.0
CMS2_k127_181559_6 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 411.0
CMS2_k127_181559_7 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 365.0
CMS2_k127_181559_8 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 368.0
CMS2_k127_181559_9 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 375.0
CMS2_k127_1835848_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.051e-212 671.0
CMS2_k127_1835848_1 Orn/Lys/Arg decarboxylase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 516.0
CMS2_k127_1835848_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 338.0
CMS2_k127_1835848_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 301.0
CMS2_k127_1835848_4 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000004842 240.0
CMS2_k127_1835848_5 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000006406 80.0
CMS2_k127_1850615_0 Belongs to the glutamate synthase family - - - 6.875e-243 758.0
CMS2_k127_1850615_1 Tripartite tricarboxylate transporter TctA family K07793 - - 2.55e-222 699.0
CMS2_k127_1850615_10 (Lipo)protein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 319.0
CMS2_k127_1850615_11 Transcriptional regulatory protein, C terminal K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 294.0
CMS2_k127_1850615_12 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 293.0
CMS2_k127_1850615_13 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 302.0
CMS2_k127_1850615_14 AMP-binding enzyme K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001548 242.0
CMS2_k127_1850615_15 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000007346 231.0
CMS2_k127_1850615_16 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000003525 220.0
CMS2_k127_1850615_17 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000001273 216.0
CMS2_k127_1850615_18 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000001389 201.0
CMS2_k127_1850615_19 Dehydroquinase class II - - - 0.000000000000000000000000000000000000000000000001409 179.0
CMS2_k127_1850615_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 437.0
CMS2_k127_1850615_20 peptidyl-prolyl K03775 - 5.2.1.8 0.00000000000000000000000000000000000001765 155.0
CMS2_k127_1850615_22 - - - - 0.00000000000000000001389 104.0
CMS2_k127_1850615_23 domain, Protein K00703,K07082 - 2.4.1.21 0.00000000000000002236 89.0
CMS2_k127_1850615_24 Domain of unknown function (DUF3330) - - - 0.000000000000005392 77.0
CMS2_k127_1850615_25 - - - - 0.000000000000008947 86.0
CMS2_k127_1850615_26 Cysteine rich repeat - - - 0.000001349 57.0
CMS2_k127_1850615_28 Phage integrase family - - - 0.0007619 44.0
CMS2_k127_1850615_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 433.0
CMS2_k127_1850615_4 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 438.0
CMS2_k127_1850615_5 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 409.0
CMS2_k127_1850615_6 Transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 402.0
CMS2_k127_1850615_7 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 354.0
CMS2_k127_1850615_8 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 348.0
CMS2_k127_1850615_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 346.0
CMS2_k127_1900863_0 FAD dependent oxidoreductase - - - 2.412e-244 764.0
CMS2_k127_1900863_1 FAD dependent oxidoreductase - - - 1.71e-205 659.0
CMS2_k127_1900863_2 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000001019 160.0
CMS2_k127_1900863_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000005046 123.0
CMS2_k127_1975944_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 596.0
CMS2_k127_1975944_1 Transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 550.0
CMS2_k127_1975944_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 437.0
CMS2_k127_1975944_3 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 399.0
CMS2_k127_1975944_4 CoA binding domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000001428 209.0
CMS2_k127_1975944_5 phosphoserine phosphatase homoserine phosphotransferase bifunctional protein K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000001726 169.0
CMS2_k127_1975944_6 - - - - 0.0000000000000000000000000000000000004144 149.0
CMS2_k127_2033406_0 abc transporter K15738 - - 6.216e-210 669.0
CMS2_k127_2033406_1 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 474.0
CMS2_k127_2033406_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 338.0
CMS2_k127_2033406_3 FKBP-type peptidyl-prolyl cis-trans isomerase K03772 - 5.2.1.8 0.00000000000000000000000000000000000007642 145.0
CMS2_k127_2033406_4 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000461 138.0
CMS2_k127_2067473_0 4Fe-4S dicluster domain - - - 0.0 1288.0
CMS2_k127_2067473_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.163e-274 854.0
CMS2_k127_2067473_10 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 482.0
CMS2_k127_2067473_11 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 424.0
CMS2_k127_2067473_12 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 392.0
CMS2_k127_2067473_13 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 364.0
CMS2_k127_2067473_14 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 372.0
CMS2_k127_2067473_15 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 338.0
CMS2_k127_2067473_16 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 309.0
CMS2_k127_2067473_17 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 326.0
CMS2_k127_2067473_18 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 295.0
CMS2_k127_2067473_19 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001619 285.0
CMS2_k127_2067473_2 Protein of unknown function, DUF255 K06888 - - 5.822e-258 822.0
CMS2_k127_2067473_20 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001698 248.0
CMS2_k127_2067473_21 PFAM Bacterial protein of - - - 0.00000000000000000000000000000000000000000000000000000000000000000003671 239.0
CMS2_k127_2067473_22 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000007946 222.0
CMS2_k127_2067473_23 Protein of unknown function DUF126 K09128 - - 0.000000000000000000000000000000000000000000000000000000000000002204 220.0
CMS2_k127_2067473_24 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.000000000000000000000000000000000000000000005503 169.0
CMS2_k127_2067473_25 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000000000000000000001483 155.0
CMS2_k127_2067473_26 Cytochrome c K08738 - - 0.0000000000000000000000000000000007559 134.0
CMS2_k127_2067473_27 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000001019 119.0
CMS2_k127_2067473_28 - - - - 0.00000000000000000000000002484 114.0
CMS2_k127_2067473_3 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 610.0
CMS2_k127_2067473_4 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 602.0
CMS2_k127_2067473_5 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 552.0
CMS2_k127_2067473_6 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 523.0
CMS2_k127_2067473_7 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 511.0
CMS2_k127_2067473_8 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 478.0
CMS2_k127_2067473_9 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 491.0
CMS2_k127_2116665_0 AMP-binding enzyme C-terminal domain K18661 - - 1.284e-206 653.0
CMS2_k127_2116665_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 551.0
CMS2_k127_2116665_10 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000003498 125.0
CMS2_k127_2116665_11 CoA-transferase family III - - - 0.00000000000000000000000001242 111.0
CMS2_k127_2116665_12 PFAM sulfatase - - - 0.000000000000004356 79.0
CMS2_k127_2116665_13 Histidine kinase - - - 0.0000000002494 73.0
CMS2_k127_2116665_2 Histidine kinase K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 380.0
CMS2_k127_2116665_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 355.0
CMS2_k127_2116665_4 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 334.0
CMS2_k127_2116665_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07663 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 323.0
CMS2_k127_2116665_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 295.0
CMS2_k127_2116665_7 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000429 286.0
CMS2_k127_2116665_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002857 275.0
CMS2_k127_2116665_9 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000000000001571 227.0
CMS2_k127_2160774_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.993e-278 874.0
CMS2_k127_2160774_1 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 3.244e-200 640.0
CMS2_k127_2160774_2 Belongs to the inositol monophosphatase superfamily K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 350.0
CMS2_k127_2160774_3 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 324.0
CMS2_k127_2160774_4 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000004783 224.0
CMS2_k127_2160774_5 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000002035 222.0
CMS2_k127_2160774_6 Iron-sulfur cluster assembly transcription factor K13643 - - 0.00000002525 55.0
CMS2_k127_2176586_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 1.961e-245 793.0
CMS2_k127_2176586_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.047e-194 618.0
CMS2_k127_2176586_2 abc transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 388.0
CMS2_k127_2176586_3 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 368.0
CMS2_k127_2176586_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 357.0
CMS2_k127_2176586_5 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 337.0
CMS2_k127_2176586_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 341.0
CMS2_k127_2176586_7 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001998 278.0
CMS2_k127_2197394_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.0 1405.0
CMS2_k127_2197394_1 TRAP transporter, 4TM 12TM fusion protein - - - 1.181e-222 707.0
CMS2_k127_2197394_10 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 356.0
CMS2_k127_2197394_11 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 338.0
CMS2_k127_2197394_12 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 319.0
CMS2_k127_2197394_13 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 317.0
CMS2_k127_2197394_14 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006082 276.0
CMS2_k127_2197394_15 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000001902 258.0
CMS2_k127_2197394_16 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000001367 257.0
CMS2_k127_2197394_17 COG2202 FOG PAS PAC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001502 270.0
CMS2_k127_2197394_18 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000000006991 209.0
CMS2_k127_2197394_19 Sulfatase-modifying factor enzyme 1 K11912 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000008039 206.0
CMS2_k127_2197394_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 3.757e-194 640.0
CMS2_k127_2197394_20 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.000000000000000000000000000000000000000000000000002351 190.0
CMS2_k127_2197394_21 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000142 173.0
CMS2_k127_2197394_22 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000005862 169.0
CMS2_k127_2197394_23 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000003268 153.0
CMS2_k127_2197394_24 RESPONSE REGULATOR receiver K02658 - - 0.000000000000000000000000000000003035 134.0
CMS2_k127_2197394_25 cheY-homologous receiver domain - - - 0.0000000000000000000000000000002145 126.0
CMS2_k127_2197394_26 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000003695 127.0
CMS2_k127_2197394_27 Two component signalling adaptor domain K03408 - - 0.000000000000000000000002098 110.0
CMS2_k127_2197394_28 (Hpt) domain - - - 0.00000000000000005729 84.0
CMS2_k127_2197394_29 - - - - 0.00001418 55.0
CMS2_k127_2197394_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 590.0
CMS2_k127_2197394_4 CheY binding K03407 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 559.0
CMS2_k127_2197394_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 488.0
CMS2_k127_2197394_6 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 424.0
CMS2_k127_2197394_7 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 409.0
CMS2_k127_2197394_8 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009318 376.0
CMS2_k127_2197394_9 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 349.0
CMS2_k127_2201666_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.0 1110.0
CMS2_k127_2201666_1 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.127e-255 794.0
CMS2_k127_2201666_10 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 494.0
CMS2_k127_2201666_11 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 461.0
CMS2_k127_2201666_12 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 427.0
CMS2_k127_2201666_13 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 369.0
CMS2_k127_2201666_14 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 346.0
CMS2_k127_2201666_15 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 310.0
CMS2_k127_2201666_16 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 311.0
CMS2_k127_2201666_17 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 297.0
CMS2_k127_2201666_18 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000002469 272.0
CMS2_k127_2201666_19 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003906 284.0
CMS2_k127_2201666_2 Methyl-accepting chemotaxis protein K02660 - - 2.481e-222 710.0
CMS2_k127_2201666_20 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002613 272.0
CMS2_k127_2201666_21 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001018 256.0
CMS2_k127_2201666_22 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000005285 253.0
CMS2_k127_2201666_23 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000007559 254.0
CMS2_k127_2201666_24 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000779 221.0
CMS2_k127_2201666_25 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000291 214.0
CMS2_k127_2201666_26 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000006812 214.0
CMS2_k127_2201666_27 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000008457 207.0
CMS2_k127_2201666_28 esterase K07000 - - 0.00000000000000000000000000000000000000000000000002383 189.0
CMS2_k127_2201666_29 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000102 189.0
CMS2_k127_2201666_3 Protein involved in ribonuclease activity and hydrolase activity K01147 - 3.1.13.1 1.536e-202 654.0
CMS2_k127_2201666_30 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000004896 175.0
CMS2_k127_2201666_31 - - - - 0.0000000000000000000000000000000000000000000001207 179.0
CMS2_k127_2201666_32 Histidine triad (Hit) protein K02503 - - 0.00000000000000000000000000000000000000002487 164.0
CMS2_k127_2201666_33 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000000000000000002923 162.0
CMS2_k127_2201666_34 Chemotaxis signal transduction protein K02659 - - 0.000000000000000000000000000000000000003371 152.0
CMS2_k127_2201666_35 Redoxin domain protein - - - 0.000000000000000000000000000000000006956 144.0
CMS2_k127_2201666_36 Rubredoxin - - - 0.0000000000000000000000000000005532 125.0
CMS2_k127_2201666_37 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000001002 123.0
CMS2_k127_2201666_38 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000009984 123.0
CMS2_k127_2201666_39 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000006465 103.0
CMS2_k127_2201666_4 Acts as a magnesium transporter K06213 - - 2.33e-201 643.0
CMS2_k127_2201666_40 Membrane fusogenic activity K09806 - - 0.0000000000003789 74.0
CMS2_k127_2201666_5 Mur ligase family, catalytic domain K02558 - 6.3.2.45 4.761e-198 627.0
CMS2_k127_2201666_6 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.572e-194 618.0
CMS2_k127_2201666_7 Aminotransferase K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 614.0
CMS2_k127_2201666_8 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 540.0
CMS2_k127_2201666_9 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 508.0
CMS2_k127_2232327_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1639.0
CMS2_k127_2232327_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 484.0
CMS2_k127_2232327_2 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 498.0
CMS2_k127_2232327_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 474.0
CMS2_k127_2232327_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 417.0
CMS2_k127_2232327_5 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 407.0
CMS2_k127_2232327_6 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.0000000000000000000000000000000000000000000000000000000004594 210.0
CMS2_k127_2232327_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000001074 133.0
CMS2_k127_2244911_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 1.295e-285 894.0
CMS2_k127_2244911_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.011e-235 741.0
CMS2_k127_2244911_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 526.0
CMS2_k127_2244911_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 482.0
CMS2_k127_2244911_4 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 292.0
CMS2_k127_2244911_5 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000001528 178.0
CMS2_k127_2244911_6 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000001637 68.0
CMS2_k127_2244911_7 Protein of unknown function (DUF2917) - - - 0.0001307 48.0
CMS2_k127_2251210_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 7.924e-314 971.0
CMS2_k127_2251210_1 Fe-S oxidoreductase K21834 - - 5.043e-262 815.0
CMS2_k127_2251210_10 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000000000001369 198.0
CMS2_k127_2251210_11 Sulfur relay protein TusC DsrF K07236 - - 0.00000000000000000000000000000000000000000000000000000001412 199.0
CMS2_k127_2251210_12 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000000000000000000000000000001352 203.0
CMS2_k127_2251210_13 Sulfurtransferase TusA - - - 0.000000000000000000000000000000000000000000000003161 183.0
CMS2_k127_2251210_14 Cas6 Crispr - - - 0.00000000000000000000000000000000000002749 158.0
CMS2_k127_2251210_15 DsrH like protein K07237 - - 0.000000000000000000000000000000000008422 142.0
CMS2_k127_2251210_16 FecR protein - - - 0.0000000000000000000000000000000001455 138.0
CMS2_k127_2251210_17 - - - - 0.0000000000000000000000000002404 132.0
CMS2_k127_2251210_18 - - - - 0.0000000000000000001468 91.0
CMS2_k127_2251210_19 Histidine kinase-like ATPase domain - - - 0.0000000000000003823 89.0
CMS2_k127_2251210_2 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 1.108e-221 689.0
CMS2_k127_2251210_20 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.00000000005932 74.0
CMS2_k127_2251210_3 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.8e-213 678.0
CMS2_k127_2251210_4 CobB/CobQ-like glutamine amidotransferase domain K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 574.0
CMS2_k127_2251210_5 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 494.0
CMS2_k127_2251210_6 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 363.0
CMS2_k127_2251210_7 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 343.0
CMS2_k127_2251210_8 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 313.0
CMS2_k127_2251210_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000005189 229.0
CMS2_k127_2260199_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1547.0
CMS2_k127_2260199_1 4Fe-4S binding domain K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 451.0
CMS2_k127_2260199_10 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000006406 124.0
CMS2_k127_2260199_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 407.0
CMS2_k127_2260199_3 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 335.0
CMS2_k127_2260199_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 327.0
CMS2_k127_2260199_5 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 297.0
CMS2_k127_2260199_6 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000004405 220.0
CMS2_k127_2260199_7 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000006121 213.0
CMS2_k127_2260199_8 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000005867 162.0
CMS2_k127_2260199_9 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000001574 140.0
CMS2_k127_2313470_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1708.0
CMS2_k127_2313470_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 1.47e-197 625.0
CMS2_k127_2313470_10 - - - - 0.0000000000000000000000000005924 119.0
CMS2_k127_2313470_11 - - - - 0.00000000000000000000000005029 113.0
CMS2_k127_2313470_13 PFAM transport-associated - - - 0.0000228 55.0
CMS2_k127_2313470_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 535.0
CMS2_k127_2313470_3 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 419.0
CMS2_k127_2313470_4 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 405.0
CMS2_k127_2313470_5 Amino Acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 384.0
CMS2_k127_2313470_6 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 376.0
CMS2_k127_2313470_7 NADPH quinone - - - 0.00000000000000000000000000000000000000000000000000000000000001271 228.0
CMS2_k127_2313470_8 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000003505 211.0
CMS2_k127_2313470_9 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K00851,K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,3.1.1.31 0.00000000000000000000000000000000000000000000000000000003349 207.0
CMS2_k127_2330006_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 581.0
CMS2_k127_2330006_1 Male sterility protein K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 552.0
CMS2_k127_2330006_2 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 386.0
CMS2_k127_2330006_3 PFAM PHB de-polymerase domain protein K05973 - 3.1.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001359 271.0
CMS2_k127_2330006_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000001411 197.0
CMS2_k127_2330006_5 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000005576 144.0
CMS2_k127_2330006_6 protein conserved in bacteria - - - 0.0000000000000001375 89.0
CMS2_k127_2335483_0 Heat shock 70 kDa protein K04043 - - 1.533e-300 956.0
CMS2_k127_2335483_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652,K12673 - 2.2.1.6,2.5.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 612.0
CMS2_k127_2335483_10 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000004573 261.0
CMS2_k127_2335483_11 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000002329 173.0
CMS2_k127_2335483_12 - - - - 0.00000000000000000000000000000000000000005165 168.0
CMS2_k127_2335483_13 - - - - 0.00000000000000000000000000005343 123.0
CMS2_k127_2335483_14 dksA traR - - - 0.0000000000000000000000000003797 117.0
CMS2_k127_2335483_15 Belongs to the N-Me-Phe pilin family K02650,K02655 - - 0.0000000000000000000000003852 111.0
CMS2_k127_2335483_16 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000008259 100.0
CMS2_k127_2335483_17 LysR family K21703 - - 0.0000000000006892 71.0
CMS2_k127_2335483_2 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 564.0
CMS2_k127_2335483_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 450.0
CMS2_k127_2335483_4 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 432.0
CMS2_k127_2335483_5 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 349.0
CMS2_k127_2335483_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 328.0
CMS2_k127_2335483_7 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 328.0
CMS2_k127_2335483_8 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 259.0
CMS2_k127_2335483_9 Domain of unknown function (DUF1932) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004764 253.0
CMS2_k127_2404938_0 extracellular solute-binding protein - - - 2.767e-290 908.0
CMS2_k127_2404938_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 1.242e-255 808.0
CMS2_k127_2404938_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 572.0
CMS2_k127_2404938_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 501.0
CMS2_k127_2404938_4 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 509.0
CMS2_k127_2404938_5 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 510.0
CMS2_k127_2404938_6 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 404.0
CMS2_k127_2404938_7 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 374.0
CMS2_k127_2404938_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000001697 131.0
CMS2_k127_2404938_9 - - - - 0.0000000000000134 76.0
CMS2_k127_2427726_0 SMART alpha amylase catalytic sub domain K00705,K06044 - 2.4.1.25,5.4.99.15 0.0 1884.0
CMS2_k127_2427726_1 SMART alpha amylase catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.0 1128.0
CMS2_k127_2427726_10 Starch synthase catalytic domain K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 514.0
CMS2_k127_2427726_11 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 482.0
CMS2_k127_2427726_12 Methyltransferase K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 363.0
CMS2_k127_2427726_13 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 344.0
CMS2_k127_2427726_14 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 316.0
CMS2_k127_2427726_15 PFAM Conserved TM helix repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 306.0
CMS2_k127_2427726_16 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007262 277.0
CMS2_k127_2427726_17 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000009831 253.0
CMS2_k127_2427726_18 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000006369 228.0
CMS2_k127_2427726_19 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000001531 218.0
CMS2_k127_2427726_2 PFAM glycoside hydrolase, family 13 domain protein K01214,K02438 - 3.2.1.196,3.2.1.68 0.0 1117.0
CMS2_k127_2427726_20 - - - - 0.000000000000000000000000000000000000000000000000000000001202 211.0
CMS2_k127_2427726_21 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000000000004565 199.0
CMS2_k127_2427726_22 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000002812 191.0
CMS2_k127_2427726_23 Protein of unknown function (DUF2459) - - - 0.0000000000000000000000000000000000000000000000006744 189.0
CMS2_k127_2427726_24 homoserine transmembrane transporter activity K03329 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000006192 176.0
CMS2_k127_2427726_25 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000005576 142.0
CMS2_k127_2427726_26 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000006686 118.0
CMS2_k127_2427726_27 KTSC domain - - - 0.0000002321 63.0
CMS2_k127_2427726_3 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1098.0
CMS2_k127_2427726_4 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 1.066e-306 966.0
CMS2_k127_2427726_5 SMART alpha amylase catalytic sub domain K01236 - 3.2.1.141 5.753e-248 786.0
CMS2_k127_2427726_6 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 1.824e-205 669.0
CMS2_k127_2427726_7 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 572.0
CMS2_k127_2427726_8 DinB superfamily K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 572.0
CMS2_k127_2427726_9 Belongs to the selenophosphate synthase 1 family. Class I subfamily K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 563.0
CMS2_k127_2531915_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 2.888e-307 958.0
CMS2_k127_2531915_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 591.0
CMS2_k127_2531915_10 PFAM NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000001327 226.0
CMS2_k127_2531915_11 Nitrogen regulatory protein P-II K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000005934 200.0
CMS2_k127_2531915_12 Small MutS-related domain - - - 0.0000000000000000000000000000000000000000000000000125 185.0
CMS2_k127_2531915_13 Pilin (bacterial filament) K02650 - - 0.0000000000000000000000000000000000000000000000833 189.0
CMS2_k127_2531915_14 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000000000000000000000001427 130.0
CMS2_k127_2531915_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 561.0
CMS2_k127_2531915_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 527.0
CMS2_k127_2531915_4 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 500.0
CMS2_k127_2531915_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 438.0
CMS2_k127_2531915_6 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 436.0
CMS2_k127_2531915_7 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 366.0
CMS2_k127_2531915_8 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001512 257.0
CMS2_k127_2531915_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000001764 221.0
CMS2_k127_2541217_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 5.468e-251 776.0
CMS2_k127_2541217_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 578.0
CMS2_k127_2541217_11 CoA-transferase family III - - - 0.000000000000000000000000001353 113.0
CMS2_k127_2541217_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 569.0
CMS2_k127_2541217_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 397.0
CMS2_k127_2541217_4 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 360.0
CMS2_k127_2541217_5 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 300.0
CMS2_k127_2541217_6 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 313.0
CMS2_k127_2541217_7 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 303.0
CMS2_k127_2541217_8 Domain of unknown function DUF108 K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000001614 250.0
CMS2_k127_2541217_9 MaoC like domain K18290 - 4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000002835 216.0
CMS2_k127_2557446_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1108.0
CMS2_k127_2557446_1 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 4.398e-209 663.0
CMS2_k127_2557446_2 LPPG Fo 2-phospho-L-lactate transferase K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001659 292.0
CMS2_k127_2557446_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006762 246.0
CMS2_k127_2557446_4 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000002074 219.0
CMS2_k127_2557446_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000006867 206.0
CMS2_k127_2557446_6 - - - - 0.00000000000000000000000000000000000000000565 166.0
CMS2_k127_2557446_7 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.000000000000000000000000000000000002473 141.0
CMS2_k127_2557446_8 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000002122 120.0
CMS2_k127_256245_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.05e-300 940.0
CMS2_k127_256245_1 Cytochrome c-type biogenesis protein CcmF K02198 - - 1.352e-279 878.0
CMS2_k127_256245_10 - - - - 0.00000000000384 72.0
CMS2_k127_256245_2 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 520.0
CMS2_k127_256245_3 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000001134 235.0
CMS2_k127_256245_4 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000002641 207.0
CMS2_k127_256245_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000006196 180.0
CMS2_k127_256245_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000001199 172.0
CMS2_k127_256245_7 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000008799 140.0
CMS2_k127_256245_8 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000001596 102.0
CMS2_k127_256245_9 E1-E2 ATPase K01533,K01534,K12954,K17686 - 3.6.3.3,3.6.3.4,3.6.3.5,3.6.3.54 0.000000000000375 74.0
CMS2_k127_2574510_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 7.326e-223 717.0
CMS2_k127_2574510_1 glycolate oxidase iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 352.0
CMS2_k127_2673544_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 4.034e-313 981.0
CMS2_k127_2673544_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 3.046e-251 781.0
CMS2_k127_2673544_2 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 515.0
CMS2_k127_2673544_3 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 467.0
CMS2_k127_2673544_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 405.0
CMS2_k127_2673544_5 ABC-type Fe3 transport system, permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 362.0
CMS2_k127_2673544_6 Phosphopantetheine attachment site - - - 0.0000000000000000000000751 113.0
CMS2_k127_2680761_0 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 435.0
CMS2_k127_2680761_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000001363 199.0
CMS2_k127_2680761_2 acetyltransferase - - - 0.0000000000000000000000000000000000000006915 161.0
CMS2_k127_2680761_3 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.0000000000000000000004606 97.0
CMS2_k127_2711712_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 6.334e-315 981.0
CMS2_k127_2711712_1 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 474.0
CMS2_k127_2711712_10 KTSC domain - - - 0.0000000000004035 77.0
CMS2_k127_2711712_11 response regulator K02282 - - 0.0000000003071 61.0
CMS2_k127_2711712_2 COG3639 ABC-type phosphate phosphonate transport system, permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 377.0
CMS2_k127_2711712_3 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 370.0
CMS2_k127_2711712_4 Binding-protein-dependent transport system inner membrane component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 357.0
CMS2_k127_2711712_5 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 333.0
CMS2_k127_2711712_6 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 311.0
CMS2_k127_2711712_7 - - - - 0.00000000000000000000000000000000000000000000000000000008655 206.0
CMS2_k127_2711712_8 Protein of unknown function (DUF2946) - - - 0.000000000000000000000000000000000000000000396 164.0
CMS2_k127_2711712_9 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000002003 143.0
CMS2_k127_2724213_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.246e-306 948.0
CMS2_k127_2724213_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 6.924e-209 655.0
CMS2_k127_2724213_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 312.0
CMS2_k127_2724213_11 Sigma E regulatory protein, MucB RseB K03598 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000014 267.0
CMS2_k127_2724213_12 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000001133 246.0
CMS2_k127_2724213_13 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000001494 217.0
CMS2_k127_2724213_14 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000001803 133.0
CMS2_k127_2724213_15 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000003308 134.0
CMS2_k127_2724213_16 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.000000000000000000000000000001399 127.0
CMS2_k127_2724213_17 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000004131 116.0
CMS2_k127_2724213_18 PFAM glutaredoxin 2 - - - 0.000000000000000000003779 95.0
CMS2_k127_2724213_19 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.000000000000000003858 93.0
CMS2_k127_2724213_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 604.0
CMS2_k127_2724213_20 Domain of unknown function (DUF4845) - - - 0.0000000000000003239 85.0
CMS2_k127_2724213_21 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0002177 44.0
CMS2_k127_2724213_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 484.0
CMS2_k127_2724213_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 438.0
CMS2_k127_2724213_5 signal peptide peptidase K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 399.0
CMS2_k127_2724213_6 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 391.0
CMS2_k127_2724213_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 392.0
CMS2_k127_2724213_8 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 349.0
CMS2_k127_2724213_9 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 345.0
CMS2_k127_275208_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1231.0
CMS2_k127_275208_1 AcrB/AcrD/AcrF family - - - 0.0 1224.0
CMS2_k127_275208_10 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 464.0
CMS2_k127_275208_11 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 439.0
CMS2_k127_275208_12 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 445.0
CMS2_k127_275208_13 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 436.0
CMS2_k127_275208_14 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 462.0
CMS2_k127_275208_15 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 424.0
CMS2_k127_275208_16 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 413.0
CMS2_k127_275208_17 Dehydrogenase K15054 - 1.1.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 405.0
CMS2_k127_275208_18 COG0501 Zn-dependent protease with chaperone function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 395.0
CMS2_k127_275208_19 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 377.0
CMS2_k127_275208_2 FAD linked oxidase domain protein K06911 - - 0.0 1197.0
CMS2_k127_275208_20 luciferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 363.0
CMS2_k127_275208_21 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 362.0
CMS2_k127_275208_22 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 358.0
CMS2_k127_275208_23 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 345.0
CMS2_k127_275208_24 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 353.0
CMS2_k127_275208_25 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 332.0
CMS2_k127_275208_26 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 305.0
CMS2_k127_275208_27 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 298.0
CMS2_k127_275208_28 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001099 281.0
CMS2_k127_275208_29 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001868 265.0
CMS2_k127_275208_3 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.0 1038.0
CMS2_k127_275208_30 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001453 267.0
CMS2_k127_275208_31 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006441 259.0
CMS2_k127_275208_32 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002406 267.0
CMS2_k127_275208_33 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008824 248.0
CMS2_k127_275208_34 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001342 240.0
CMS2_k127_275208_35 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000004564 254.0
CMS2_k127_275208_36 Sulfatase-modifying factor enzyme 1 K11912 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001638 244.0
CMS2_k127_275208_37 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000009035 237.0
CMS2_k127_275208_38 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000004359 218.0
CMS2_k127_275208_39 PFAM Bacterial regulatory proteins, gntR family, FCD domain - - - 0.0000000000000000000000000000000000000000000000000000000002442 211.0
CMS2_k127_275208_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 8.551e-220 706.0
CMS2_k127_275208_40 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000002621 198.0
CMS2_k127_275208_41 carbon monoxide dehydrogenase K09386 - - 0.000000000000000000000000000000000000000000000009087 191.0
CMS2_k127_275208_42 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000008447 169.0
CMS2_k127_275208_43 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000000000004819 156.0
CMS2_k127_275208_44 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000001871 118.0
CMS2_k127_275208_45 spectrin binding - - - 0.0000000000000000000000000005115 123.0
CMS2_k127_275208_46 transcriptional regulator - - - 0.00000000000000000000000001063 122.0
CMS2_k127_275208_47 - - - - 0.0000000000000000000000001367 113.0
CMS2_k127_275208_48 - - - - 0.0000013 58.0
CMS2_k127_275208_5 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K08295 - 6.2.1.32 1.667e-208 679.0
CMS2_k127_275208_50 Adenylate cyclase K01768 - 4.6.1.1 0.00002699 54.0
CMS2_k127_275208_51 cellulase activity - - - 0.0001011 54.0
CMS2_k127_275208_6 PFAM Sulfatase K01130 - 3.1.6.1 8.415e-206 647.0
CMS2_k127_275208_7 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 551.0
CMS2_k127_275208_8 General function prediction only K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 548.0
CMS2_k127_275208_9 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 482.0
CMS2_k127_2753426_0 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 7.412e-202 633.0
CMS2_k127_2753426_1 Ethylbenzene dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 566.0
CMS2_k127_2753426_10 Serine hydrolase (FSH1) K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002021 280.0
CMS2_k127_2753426_11 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004773 269.0
CMS2_k127_2753426_12 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0000000000000000000000000000000000000000000000000000000000000000004207 238.0
CMS2_k127_2753426_13 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000003298 209.0
CMS2_k127_2753426_14 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000008755 199.0
CMS2_k127_2753426_15 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000001403 194.0
CMS2_k127_2753426_16 Glutaredoxin - - - 0.0000000000000000000000000000000000000000000002281 169.0
CMS2_k127_2753426_17 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000001873 171.0
CMS2_k127_2753426_18 - - - - 0.000000000000000000000000000000000000000001056 164.0
CMS2_k127_2753426_19 HNH nucleases - - - 0.00000000000000000000000000000000000000002738 164.0
CMS2_k127_2753426_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 469.0
CMS2_k127_2753426_20 MazG-like family - - - 0.000000000000000000000000000000000001148 141.0
CMS2_k127_2753426_21 Restriction endonuclease K07448 - - 0.000000000000000000000000000000000003432 143.0
CMS2_k127_2753426_22 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000002567 139.0
CMS2_k127_2753426_23 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000008276 122.0
CMS2_k127_2753426_24 nuclease - - - 0.0000000000006928 80.0
CMS2_k127_2753426_25 serine threonine protein kinase - - - 0.000000633 58.0
CMS2_k127_2753426_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 477.0
CMS2_k127_2753426_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 410.0
CMS2_k127_2753426_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 377.0
CMS2_k127_2753426_6 iron assimilation K07223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 372.0
CMS2_k127_2753426_7 Acyl-CoA dehydrogenase, C-terminal domain K16047 - 1.14.14.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 349.0
CMS2_k127_2753426_8 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 308.0
CMS2_k127_2753426_9 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001343 275.0
CMS2_k127_2771739_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 8.012e-258 801.0
CMS2_k127_2771739_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 6.059e-213 676.0
CMS2_k127_2771739_10 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 430.0
CMS2_k127_2771739_11 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 391.0
CMS2_k127_2771739_12 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 397.0
CMS2_k127_2771739_13 2-hydroxy-3-oxopropionate reductase K00020,K08319 - 1.1.1.31,1.1.1.411 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 358.0
CMS2_k127_2771739_14 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 348.0
CMS2_k127_2771739_15 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 342.0
CMS2_k127_2771739_16 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 344.0
CMS2_k127_2771739_17 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 325.0
CMS2_k127_2771739_18 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 322.0
CMS2_k127_2771739_19 acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 294.0
CMS2_k127_2771739_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 605.0
CMS2_k127_2771739_20 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 295.0
CMS2_k127_2771739_21 peptidase, M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002186 280.0
CMS2_k127_2771739_22 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001294 282.0
CMS2_k127_2771739_23 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000144 266.0
CMS2_k127_2771739_24 Pyrimidine 5''-nucleotidase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005771 247.0
CMS2_k127_2771739_25 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000004338 238.0
CMS2_k127_2771739_26 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000002117 228.0
CMS2_k127_2771739_27 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000003125 222.0
CMS2_k127_2771739_28 Bacterial regulatory proteins, tetR family K05501 - - 0.000000000000000000000000000000000000000000000000000000000005142 223.0
CMS2_k127_2771739_29 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000003331 201.0
CMS2_k127_2771739_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 595.0
CMS2_k127_2771739_30 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000007097 199.0
CMS2_k127_2771739_31 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000001028 184.0
CMS2_k127_2771739_32 coa-binding K06929 - - 0.0000000000000000000000000000000000000000000003152 170.0
CMS2_k127_2771739_33 Cupin domain - - - 0.000000000000000000000000000000000000000000006733 167.0
CMS2_k127_2771739_34 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000009647 166.0
CMS2_k127_2771739_35 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000002356 154.0
CMS2_k127_2771739_36 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000001873 145.0
CMS2_k127_2771739_37 Bacterial SH3 domain - - - 0.0000000000000000000000000000000001736 145.0
CMS2_k127_2771739_38 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000006614 125.0
CMS2_k127_2771739_39 Putative zinc-finger - - - 0.000000000003369 68.0
CMS2_k127_2771739_4 Putative nucleotide-binding of sugar-metabolising enzyme K21948 - 2.7.1.217 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 547.0
CMS2_k127_2771739_40 Cysteine-rich CWC - - - 0.00001179 52.0
CMS2_k127_2771739_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 509.0
CMS2_k127_2771739_6 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 465.0
CMS2_k127_2771739_7 Cobalamin synthesis protein cobW C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 458.0
CMS2_k127_2771739_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 447.0
CMS2_k127_2771739_9 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 450.0
CMS2_k127_2772005_0 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 1.324e-273 850.0
CMS2_k127_2772005_1 Thiolase, C-terminal domain - - - 2.092e-196 631.0
CMS2_k127_2772005_10 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000001195 88.0
CMS2_k127_2772005_2 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 600.0
CMS2_k127_2772005_3 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 505.0
CMS2_k127_2772005_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 330.0
CMS2_k127_2772005_5 GntR family - - - 0.000000000000000000000000000000000000000000000000000000000000000003062 232.0
CMS2_k127_2772005_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000723 234.0
CMS2_k127_2772005_7 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.0000000000000000000000000000000000000000000000000000001498 214.0
CMS2_k127_2772005_8 2 iron, 2 sulfur cluster binding K03518,K07302 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000003353 171.0
CMS2_k127_2772005_9 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000002675 147.0
CMS2_k127_2781237_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 522.0
CMS2_k127_2781237_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 477.0
CMS2_k127_2781237_2 Cupin - - - 0.000000000002328 72.0
CMS2_k127_2781237_3 Protein of unknown function (DUF2798) - - - 0.00000005133 63.0
CMS2_k127_2796283_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 598.0
CMS2_k127_2796283_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 528.0
CMS2_k127_2796283_11 metal-binding protein - - - 0.000000000000000000000000000000000000000000001762 171.0
CMS2_k127_2796283_12 PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30 - - - 0.000000000000000000000000000000000000000002274 160.0
CMS2_k127_2796283_13 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000003946 159.0
CMS2_k127_2796283_14 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000000000001067 149.0
CMS2_k127_2796283_15 ABC transporter transmembrane region K06148 - - 0.00000000000000000000000000000000001564 141.0
CMS2_k127_2796283_16 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000001017 113.0
CMS2_k127_2796283_17 SCO1/SenC K07152 - - 0.000000000000000000000000008767 123.0
CMS2_k127_2796283_18 protein histidine kinase activity K06375 - - 0.00000000000000001654 91.0
CMS2_k127_2796283_19 Multicopper oxidase K20219 - 1.10.3.4 0.000000000000005276 80.0
CMS2_k127_2796283_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 501.0
CMS2_k127_2796283_20 LTXXQ motif family protein - - - 0.0000000000104 74.0
CMS2_k127_2796283_21 Domain of unknown function DUF302 - - - 0.00000000172 60.0
CMS2_k127_2796283_22 - - - - 0.00000002714 61.0
CMS2_k127_2796283_23 Multicopper oxidase K22350 - 1.16.3.3 0.00000005178 57.0
CMS2_k127_2796283_24 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000007572 60.0
CMS2_k127_2796283_25 Protein of unknown function (DUF1573) - - - 0.000001515 57.0
CMS2_k127_2796283_26 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00001281 53.0
CMS2_k127_2796283_3 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 498.0
CMS2_k127_2796283_4 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 388.0
CMS2_k127_2796283_5 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 336.0
CMS2_k127_2796283_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 306.0
CMS2_k127_2796283_8 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 305.0
CMS2_k127_2796283_9 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006953 253.0
CMS2_k127_2827366_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 6.957e-257 807.0
CMS2_k127_2827366_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 8.712e-201 651.0
CMS2_k127_2827366_2 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 499.0
CMS2_k127_2827366_3 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000006826 283.0
CMS2_k127_2827366_4 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000668 261.0
CMS2_k127_2827366_5 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000009368 177.0
CMS2_k127_2827366_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000002161 147.0
CMS2_k127_2827366_7 Iron-sulphur cluster assembly - - - 0.000000000000000000000000004959 111.0
CMS2_k127_2827366_8 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000003899 57.0
CMS2_k127_2847827_0 Carbon-nitrogen hydrolase K01502 - 3.5.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007639 330.0
CMS2_k127_2847827_1 Acyl-CoA dehydrogenase, C-terminal domain K08297,K20035 - 1.3.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 340.0
CMS2_k127_2847827_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 313.0
CMS2_k127_2847827_3 - - - - 0.00000000000000000000000000000000000000000000000191 182.0
CMS2_k127_2847827_4 - - - - 0.00000000000000000000000000000000000000000001627 166.0
CMS2_k127_2847827_5 PFAM Dimethylmenaquinone methyltransferase - - - 0.00000000000000000000000000000000000000465 157.0
CMS2_k127_2847827_6 TIGRFAM phosphonopyruvate decarboxylase-related protein K15635 - 5.4.2.12 0.0000000000000000000000000000001163 143.0
CMS2_k127_2847827_7 endoribonuclease L-PSP - - - 0.0000000000003844 82.0
CMS2_k127_2886723_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.225e-256 798.0
CMS2_k127_2886723_1 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 5.548e-206 656.0
CMS2_k127_2886723_10 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 324.0
CMS2_k127_2886723_11 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 319.0
CMS2_k127_2886723_12 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 300.0
CMS2_k127_2886723_13 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001361 287.0
CMS2_k127_2886723_14 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000007365 204.0
CMS2_k127_2886723_15 synthesis repressor, PhaR - - - 0.0000000000000000000000000000000000000003317 151.0
CMS2_k127_2886723_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 610.0
CMS2_k127_2886723_3 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 524.0
CMS2_k127_2886723_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 452.0
CMS2_k127_2886723_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 387.0
CMS2_k127_2886723_6 Male sterility protein K22025 - 1.1.1.410 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 366.0
CMS2_k127_2886723_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 367.0
CMS2_k127_2886723_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 334.0
CMS2_k127_2886723_9 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 328.0
CMS2_k127_2966300_0 AMP-binding enzyme C-terminal domain - - - 4.741e-222 698.0
CMS2_k127_2966300_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 508.0
CMS2_k127_2966300_2 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 342.0
CMS2_k127_2966300_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
CMS2_k127_2979033_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 8.596e-295 922.0
CMS2_k127_2979033_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 490.0
CMS2_k127_2979033_10 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000000002084 202.0
CMS2_k127_2979033_11 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000004923 186.0
CMS2_k127_2979033_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 466.0
CMS2_k127_2979033_3 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 380.0
CMS2_k127_2979033_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 364.0
CMS2_k127_2979033_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 335.0
CMS2_k127_2979033_6 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000315 284.0
CMS2_k127_2979033_7 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003696 269.0
CMS2_k127_2979033_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000006103 235.0
CMS2_k127_2979033_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000008985 198.0
CMS2_k127_2986421_0 PFAM AMP-dependent synthetase and ligase - - - 3.868e-228 716.0
CMS2_k127_2986421_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 567.0
CMS2_k127_2986421_10 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.00000000000000000000000000000000000000000000000000000005489 204.0
CMS2_k127_2986421_11 - - - - 0.000000000000000000000000000000000000003601 151.0
CMS2_k127_2986421_12 Major facilitator Superfamily - - - 0.000000000000000000000004985 116.0
CMS2_k127_2986421_2 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 508.0
CMS2_k127_2986421_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 480.0
CMS2_k127_2986421_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 395.0
CMS2_k127_2986421_5 Binding-protein-dependent transport system inner membrane component K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 394.0
CMS2_k127_2986421_6 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 378.0
CMS2_k127_2986421_7 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001107 257.0
CMS2_k127_2986421_8 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000006588 241.0
CMS2_k127_2986421_9 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000007242 223.0
CMS2_k127_2998761_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 9.209e-312 975.0
CMS2_k127_2998761_1 Carbamoyltransferase K00612 - - 1.612e-296 924.0
CMS2_k127_2998761_10 - - - - 0.000000000000000000000000000000000000000000000002735 181.0
CMS2_k127_2998761_11 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000000000000000000000000000002791 182.0
CMS2_k127_2998761_12 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000008718 172.0
CMS2_k127_2998761_13 - - - - 0.000000000000000000000000000000000002865 142.0
CMS2_k127_2998761_14 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000176 125.0
CMS2_k127_2998761_15 Copper binding periplasmic protein CusF - - - 0.0000000000000000000000000686 118.0
CMS2_k127_2998761_16 LTXXQ motif family protein - - - 0.0000000000000000000000001856 113.0
CMS2_k127_2998761_17 - - - - 0.000000000000000000000005166 109.0
CMS2_k127_2998761_18 Short C-terminal domain K08982 - - 0.0000000000000000006866 90.0
CMS2_k127_2998761_19 - - - - 0.000000000000003182 80.0
CMS2_k127_2998761_2 multicopper oxidase type 3 K22348 - 1.16.3.3 2.688e-233 734.0
CMS2_k127_2998761_20 - - - - 0.000000000002328 72.0
CMS2_k127_2998761_21 - - - - 0.00009202 51.0
CMS2_k127_2998761_22 - - - - 0.0002323 49.0
CMS2_k127_2998761_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 445.0
CMS2_k127_2998761_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 359.0
CMS2_k127_2998761_5 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002457 282.0
CMS2_k127_2998761_6 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008136 276.0
CMS2_k127_2998761_7 periplasmic protein thiol disulfide K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000926 258.0
CMS2_k127_2998761_8 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002164 271.0
CMS2_k127_2998761_9 helix_turn_helix, mercury resistance K19591,K19592 - - 0.0000000000000000000000000000000000000000000000000005741 190.0
CMS2_k127_3022274_0 GXGXG motif K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2364.0
CMS2_k127_3022274_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1301.0
CMS2_k127_3022274_10 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 596.0
CMS2_k127_3022274_11 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 567.0
CMS2_k127_3022274_12 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 552.0
CMS2_k127_3022274_13 Pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 472.0
CMS2_k127_3022274_14 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 451.0
CMS2_k127_3022274_15 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 423.0
CMS2_k127_3022274_16 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 404.0
CMS2_k127_3022274_17 4Fe-4S binding domain K18362 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 381.0
CMS2_k127_3022274_18 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 373.0
CMS2_k127_3022274_19 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 331.0
CMS2_k127_3022274_2 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 3.329e-312 974.0
CMS2_k127_3022274_20 Outer membrane phospholipase A K01058 - 3.1.1.32,3.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000784 290.0
CMS2_k127_3022274_21 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000002338 229.0
CMS2_k127_3022274_22 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000001274 234.0
CMS2_k127_3022274_23 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000002785 218.0
CMS2_k127_3022274_24 DMSO reductase anchor subunit (DmsC) K18363 - - 0.000000000000000000000000000000000000000000000000000000000002156 227.0
CMS2_k127_3022274_25 fimbrial biogenesis protein PilN K02663 - - 0.00000000000000000000000000000000000000000000000000000000005688 212.0
CMS2_k127_3022274_26 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000006989 188.0
CMS2_k127_3022274_27 pilus assembly protein PilP K02665 - - 0.0000000000000000000000000000000000000000001932 165.0
CMS2_k127_3022274_28 ferredoxin - - - 0.00000000000000000000000000000000000001955 146.0
CMS2_k127_3022274_29 Thioesterase - - - 0.0000000000000000000000000000000008632 132.0
CMS2_k127_3022274_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.147e-270 842.0
CMS2_k127_3022274_30 Rubrerythrin - - - 0.00000000000000000000000000000001789 142.0
CMS2_k127_3022274_31 Belongs to the frataxin K06202 - - 0.0000000000000000000000000000001013 125.0
CMS2_k127_3022274_4 type II and III secretion system protein K02666 - - 1.515e-240 762.0
CMS2_k127_3022274_5 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 1.592e-240 751.0
CMS2_k127_3022274_6 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 6.179e-222 702.0
CMS2_k127_3022274_7 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 6.989e-215 674.0
CMS2_k127_3022274_8 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 627.0
CMS2_k127_3022274_9 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 582.0
CMS2_k127_3076236_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 580.0
CMS2_k127_3076236_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000002251 219.0
CMS2_k127_3076236_2 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000001846 206.0
CMS2_k127_3076236_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000002324 207.0
CMS2_k127_3076236_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000265 168.0
CMS2_k127_3076236_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000003999 150.0
CMS2_k127_3083512_0 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 501.0
CMS2_k127_3083512_1 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 434.0
CMS2_k127_3083512_2 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 417.0
CMS2_k127_3083512_3 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.0000000000000000000000000000000000000000006439 163.0
CMS2_k127_3083512_4 C4-dicarboxylate transport system - - - 0.0008138 45.0
CMS2_k127_3124043_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1482.0
CMS2_k127_3124043_1 Malic enzyme K00029 - 1.1.1.40 0.0 1072.0
CMS2_k127_3124043_10 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 498.0
CMS2_k127_3124043_11 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 479.0
CMS2_k127_3124043_12 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 461.0
CMS2_k127_3124043_13 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 434.0
CMS2_k127_3124043_14 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 422.0
CMS2_k127_3124043_15 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 433.0
CMS2_k127_3124043_16 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 382.0
CMS2_k127_3124043_17 PFAM ATP-binding region, ATPase domain protein K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 396.0
CMS2_k127_3124043_18 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 330.0
CMS2_k127_3124043_19 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 306.0
CMS2_k127_3124043_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.114e-240 751.0
CMS2_k127_3124043_20 Protein of unknown function (DUF3999) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 311.0
CMS2_k127_3124043_21 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001787 286.0
CMS2_k127_3124043_22 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009488 270.0
CMS2_k127_3124043_23 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003708 248.0
CMS2_k127_3124043_24 Protein of unknown function (DUF3187) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005578 253.0
CMS2_k127_3124043_25 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005103 249.0
CMS2_k127_3124043_26 N-acetylmuramoyl-L-alanine amidase (Family 2) K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000002731 239.0
CMS2_k127_3124043_27 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000007509 220.0
CMS2_k127_3124043_28 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000007594 218.0
CMS2_k127_3124043_29 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000004255 200.0
CMS2_k127_3124043_3 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 1.336e-238 761.0
CMS2_k127_3124043_30 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000003625 188.0
CMS2_k127_3124043_31 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000001769 157.0
CMS2_k127_3124043_32 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000002387 159.0
CMS2_k127_3124043_33 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000001425 147.0
CMS2_k127_3124043_34 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000007973 146.0
CMS2_k127_3124043_35 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000513 132.0
CMS2_k127_3124043_36 PFAM ribosomal protein L31 K02909 - - 0.000000000000000000000000001434 114.0
CMS2_k127_3124043_37 - - - - 0.000000000000000000000000984 105.0
CMS2_k127_3124043_38 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000001391 101.0
CMS2_k127_3124043_39 - - - - 0.0000000000000000005188 100.0
CMS2_k127_3124043_4 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 8.99e-208 652.0
CMS2_k127_3124043_40 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000008594 88.0
CMS2_k127_3124043_41 Rubrerythrin - - - 0.00000000000000002097 81.0
CMS2_k127_3124043_42 - K06950 - - 0.000000000005531 71.0
CMS2_k127_3124043_43 Protein of unknown function (DUF2442) - - - 0.0000000005157 63.0
CMS2_k127_3124043_44 Histone H1-like nucleoprotein HC2 K11275 - - 0.000000003471 62.0
CMS2_k127_3124043_5 Domain of unknown function (DUF4139) - - - 9.722e-199 631.0
CMS2_k127_3124043_6 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 609.0
CMS2_k127_3124043_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 526.0
CMS2_k127_3124043_8 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 518.0
CMS2_k127_3124043_9 PFAM Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 503.0
CMS2_k127_3124169_0 Aminotransferase class I and II K14261 - - 3.268e-226 705.0
CMS2_k127_3124169_1 Cysteine-rich domain - - - 2.809e-225 706.0
CMS2_k127_3124169_10 hydrolase - - - 0.00000000000000000000000000000000000000000000002593 183.0
CMS2_k127_3124169_11 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000007616 177.0
CMS2_k127_3124169_12 Small Multidrug Resistance protein - - - 0.000000000000000000000000000000000000000003958 177.0
CMS2_k127_3124169_13 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000003524 134.0
CMS2_k127_3124169_14 sigma factor antagonist activity K04757,K07315 - 2.7.11.1,3.1.3.3 0.00000000000000000002211 96.0
CMS2_k127_3124169_15 Rubrerythrin - - - 0.00000000000000002097 81.0
CMS2_k127_3124169_2 homoserine dehydrogenase K00003 - 1.1.1.3 2.135e-195 638.0
CMS2_k127_3124169_3 Threonine synthase K01733 - 4.2.3.1 6.101e-194 638.0
CMS2_k127_3124169_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 520.0
CMS2_k127_3124169_5 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 462.0
CMS2_k127_3124169_6 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009469 445.0
CMS2_k127_3124169_7 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 374.0
CMS2_k127_3124169_8 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 359.0
CMS2_k127_3124169_9 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000000000000002333 226.0
CMS2_k127_3129201_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 592.0
CMS2_k127_3129201_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 518.0
CMS2_k127_3129201_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 486.0
CMS2_k127_3129201_3 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 310.0
CMS2_k127_3129201_4 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000000000000000001147 202.0
CMS2_k127_3129201_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000002751 152.0
CMS2_k127_3129201_6 HEAT repeats - - - 0.00000000000000000000000000000000003711 151.0
CMS2_k127_3129201_7 - - - - 0.000000000000000000000001147 115.0
CMS2_k127_3166735_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.049e-238 760.0
CMS2_k127_3166735_1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 7.651e-206 647.0
CMS2_k127_3166735_10 TIGRFAM TonB family C-terminal domain K03832 - - 0.00000005173 64.0
CMS2_k127_3166735_11 Recombinase zinc beta ribbon domain - - - 0.0006148 46.0
CMS2_k127_3166735_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 529.0
CMS2_k127_3166735_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 523.0
CMS2_k127_3166735_4 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 463.0
CMS2_k127_3166735_5 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 376.0
CMS2_k127_3166735_6 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000001251 236.0
CMS2_k127_3166735_7 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000005773 181.0
CMS2_k127_3166735_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000001626 152.0
CMS2_k127_3183417_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K01817 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 400.0
CMS2_k127_3183417_1 Indole-3-glycerol phosphate synthase K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.000000000000000000000000000000000000000002421 164.0
CMS2_k127_3183417_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000011 136.0
CMS2_k127_3257369_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 605.0
CMS2_k127_3257369_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 545.0
CMS2_k127_3257369_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 461.0
CMS2_k127_3257369_3 DsbA oxidoreductase - - - 0.000000000000000000000000000000000000000000000000002147 187.0
CMS2_k127_3257369_4 - - - - 0.000000000000000000000003252 105.0
CMS2_k127_3257369_5 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000001659 97.0
CMS2_k127_3257369_6 - - - - 0.00000000000000000002626 92.0
CMS2_k127_3257369_7 peroxiredoxin activity - - - 0.00000001081 57.0
CMS2_k127_3257369_8 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.0005491 44.0
CMS2_k127_3262395_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1130.0
CMS2_k127_3262395_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.772e-285 886.0
CMS2_k127_3262395_10 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001057 245.0
CMS2_k127_3262395_11 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000001298 224.0
CMS2_k127_3262395_12 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000001061 204.0
CMS2_k127_3262395_13 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000001088 179.0
CMS2_k127_3262395_14 Oligoketide cyclase lipid transport protein - GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000005507 139.0
CMS2_k127_3262395_15 - - - - 0.00000000000000000000001654 115.0
CMS2_k127_3262395_17 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000009754 89.0
CMS2_k127_3262395_18 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000222 81.0
CMS2_k127_3262395_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.896e-239 747.0
CMS2_k127_3262395_3 BT1 family - - - 4.144e-235 739.0
CMS2_k127_3262395_4 Extracellular liganD-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 550.0
CMS2_k127_3262395_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 471.0
CMS2_k127_3262395_6 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 437.0
CMS2_k127_3262395_7 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 439.0
CMS2_k127_3262395_8 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 386.0
CMS2_k127_3262395_9 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 364.0
CMS2_k127_3268745_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1592.0
CMS2_k127_3268745_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1142.0
CMS2_k127_3268745_10 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000002358 214.0
CMS2_k127_3268745_11 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000002009 161.0
CMS2_k127_3268745_12 Sulfurtransferase TusA K04085 - - 0.000000000000000000000000000000004722 128.0
CMS2_k127_3268745_13 - - - - 0.000000000000000000000000005111 113.0
CMS2_k127_3268745_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 4.591e-227 728.0
CMS2_k127_3268745_3 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 7.214e-214 671.0
CMS2_k127_3268745_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 475.0
CMS2_k127_3268745_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 461.0
CMS2_k127_3268745_6 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 430.0
CMS2_k127_3268745_7 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 349.0
CMS2_k127_3268745_8 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 329.0
CMS2_k127_3268745_9 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000008307 230.0
CMS2_k127_3279095_0 argininosuccinate lyase K01755 - 4.3.2.1 1.12e-199 634.0
CMS2_k127_3279095_1 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 555.0
CMS2_k127_3279095_10 HemX, putative uroporphyrinogen-III C-methyltransferase K02496 - 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003308 298.0
CMS2_k127_3279095_11 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000001666 271.0
CMS2_k127_3279095_12 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003178 272.0
CMS2_k127_3279095_13 uroporphyrinogen III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000001763 273.0
CMS2_k127_3279095_14 enzyme of heme biosynthesis K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003706 262.0
CMS2_k127_3279095_15 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000001352 175.0
CMS2_k127_3279095_16 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000003525 129.0
CMS2_k127_3279095_17 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000007001 111.0
CMS2_k127_3279095_18 Thioredoxin-like domain - - - 0.0000000000000000000000003699 113.0
CMS2_k127_3279095_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 541.0
CMS2_k127_3279095_20 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000001438 50.0
CMS2_k127_3279095_3 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 530.0
CMS2_k127_3279095_4 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 506.0
CMS2_k127_3279095_5 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 473.0
CMS2_k127_3279095_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 404.0
CMS2_k127_3279095_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 361.0
CMS2_k127_3279095_8 PFAM Fructosamine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 310.0
CMS2_k127_3279095_9 alginate biosynthesis protein AlgZ FimS K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 293.0
CMS2_k127_3299412_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 6.348e-243 757.0
CMS2_k127_3299412_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 415.0
CMS2_k127_3299412_10 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
CMS2_k127_3299412_11 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000003999 205.0
CMS2_k127_3299412_12 - - - - 0.000000000000000000000000000000000000000000000000000006325 205.0
CMS2_k127_3299412_13 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000003072 188.0
CMS2_k127_3299412_14 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000002798 194.0
CMS2_k127_3299412_15 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000000000008255 184.0
CMS2_k127_3299412_16 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000002456 190.0
CMS2_k127_3299412_17 - - - - 0.0000000000000000000000000000000009379 137.0
CMS2_k127_3299412_18 - - - - 0.00000000000000000005033 99.0
CMS2_k127_3299412_2 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 385.0
CMS2_k127_3299412_20 Cytochrome c7 and related cytochrome c - - - 0.00000001928 60.0
CMS2_k127_3299412_21 Zinc-ribbon containing domain - - - 0.0000001389 61.0
CMS2_k127_3299412_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 368.0
CMS2_k127_3299412_4 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 352.0
CMS2_k127_3299412_5 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 348.0
CMS2_k127_3299412_6 SurA N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 305.0
CMS2_k127_3299412_7 Pfam Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 295.0
CMS2_k127_3299412_8 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004895 263.0
CMS2_k127_3299412_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004301 267.0
CMS2_k127_3305878_0 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 1.198e-225 711.0
CMS2_k127_3305878_1 Pyridoxal phosphate biosynthetic protein PdxA K22024 - 1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 492.0
CMS2_k127_3305878_10 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000002621 168.0
CMS2_k127_3305878_2 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 489.0
CMS2_k127_3305878_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 338.0
CMS2_k127_3305878_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 309.0
CMS2_k127_3305878_5 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 307.0
CMS2_k127_3305878_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 299.0
CMS2_k127_3305878_7 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001026 284.0
CMS2_k127_3305878_8 RNA methyltransferase K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000005317 244.0
CMS2_k127_3305878_9 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000001182 220.0
CMS2_k127_3323203_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.627e-291 909.0
CMS2_k127_3323203_1 Metallopeptidase family M24 - - - 9.154e-212 666.0
CMS2_k127_3323203_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 500.0
CMS2_k127_3323203_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 366.0
CMS2_k127_3323203_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 306.0
CMS2_k127_332471_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1120.0
CMS2_k127_332471_1 serine protease K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 493.0
CMS2_k127_332471_2 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 379.0
CMS2_k127_332471_3 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003728 246.0
CMS2_k127_332471_4 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000000000002475 160.0
CMS2_k127_3327072_0 Quinone oxidoreductase K00001,K00344 - 1.1.1.1,1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 368.0
CMS2_k127_3327072_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 339.0
CMS2_k127_3327072_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000002071 141.0
CMS2_k127_3370072_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 9.597e-255 794.0
CMS2_k127_3370072_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 4.209e-236 741.0
CMS2_k127_3370072_10 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000203 230.0
CMS2_k127_3370072_11 cyclic nucleotide binding K01420 - - 0.0000000000000000000000000000000000000000000000000000000001067 213.0
CMS2_k127_3370072_12 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000005004 147.0
CMS2_k127_3370072_13 Alpha/beta hydrolase family - - - 0.00000000000000000000000000001039 125.0
CMS2_k127_3370072_14 Thioesterase superfamily protein - - - 0.0000000000000000000000001542 107.0
CMS2_k127_3370072_2 Aspartate ammonia-lyase K01744 - 4.3.1.1 1.448e-221 695.0
CMS2_k127_3370072_3 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.118e-216 678.0
CMS2_k127_3370072_4 Zinc-binding dehydrogenase K12957,K13953,K19961 - 1.1.1.1,1.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 400.0
CMS2_k127_3370072_5 PFAM formate nitrite transporter K06212,K21993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 366.0
CMS2_k127_3370072_6 Carboxylesterase family K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 322.0
CMS2_k127_3370072_7 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 326.0
CMS2_k127_3370072_8 Glutathione S-Transferase K00799 GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016740,GO:0016765,GO:0030611,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003481 276.0
CMS2_k127_3370072_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004021 255.0
CMS2_k127_3378508_0 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 574.0
CMS2_k127_3378508_1 auxin efflux carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 331.0
CMS2_k127_3378508_2 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001743 250.0
CMS2_k127_3378508_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005715 235.0
CMS2_k127_3378508_4 DsrC like protein - - - 0.00000000000000000000000000000000000000007209 151.0
CMS2_k127_3410444_0 DNA polymerase K02337 - 2.7.7.7 0.0 1440.0
CMS2_k127_3410444_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 1.13e-196 629.0
CMS2_k127_3410444_2 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 472.0
CMS2_k127_3410444_3 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 306.0
CMS2_k127_3410444_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001734 272.0
CMS2_k127_3410444_5 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000008808 142.0
CMS2_k127_3410444_6 - - - - 0.0000000000000000000000001004 116.0
CMS2_k127_3410444_7 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000004685 99.0
CMS2_k127_3410444_9 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00007901 46.0
CMS2_k127_341929_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 625.0
CMS2_k127_341929_1 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 593.0
CMS2_k127_341929_2 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 391.0
CMS2_k127_341929_3 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 364.0
CMS2_k127_341929_4 PFAM NADH Ubiquinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004262 253.0
CMS2_k127_341929_5 TIGRFAM carbohydrate kinase, thermoresistant glucokinase family K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000000000000000000003675 219.0
CMS2_k127_341929_6 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000003112 177.0
CMS2_k127_341929_7 cytidyltransferase-related domain K00952 - 2.7.7.1 0.000000000000000000000000000000002206 136.0
CMS2_k127_3426245_0 transport system fused permease components - - - 6.905e-246 778.0
CMS2_k127_3426245_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 559.0
CMS2_k127_3426245_2 TRAP transporter solute receptor TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 454.0
CMS2_k127_3426245_3 Histidine kinase K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000004571 245.0
CMS2_k127_3426245_4 Response regulator receiver K15012 - - 0.000000000000000000000000000000000000000000000000000003062 198.0
CMS2_k127_3426245_5 Multicopper oxidase K22349 - 1.16.3.3 0.0000001766 56.0
CMS2_k127_3444206_0 CHASE2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 477.0
CMS2_k127_3444206_1 Cache 3/Cache 2 fusion domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 461.0
CMS2_k127_3444206_2 hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 393.0
CMS2_k127_3444206_3 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 368.0
CMS2_k127_3444206_4 OmpA family - - - 0.00000000000000000000000000000001066 139.0
CMS2_k127_3444206_5 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.0000000000000000000108 98.0
CMS2_k127_3444206_6 STAS domain K06378 - - 0.00000000000000000001723 96.0
CMS2_k127_3463446_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1121.0
CMS2_k127_3466353_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 5.974e-282 893.0
CMS2_k127_3466353_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 469.0
CMS2_k127_3490870_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.763e-204 651.0
CMS2_k127_3490870_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 517.0
CMS2_k127_3490870_10 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000003205 212.0
CMS2_k127_3490870_11 protein affecting Mg2 Co2 transport K06195 - - 0.000000000000000000000000000000000000000000000000000002036 193.0
CMS2_k127_3490870_12 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000003554 149.0
CMS2_k127_3490870_13 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000001283 145.0
CMS2_k127_3490870_14 - - - - 0.000000000007807 69.0
CMS2_k127_3490870_2 phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 465.0
CMS2_k127_3490870_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 459.0
CMS2_k127_3490870_4 membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 412.0
CMS2_k127_3490870_5 Mg2 and Co2 transporter CorC K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 390.0
CMS2_k127_3490870_6 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 355.0
CMS2_k127_3490870_7 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 361.0
CMS2_k127_3490870_8 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000001217 247.0
CMS2_k127_3490870_9 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000002802 235.0
CMS2_k127_3526387_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 1015.0
CMS2_k127_3565378_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 342.0
CMS2_k127_3565378_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000033 196.0
CMS2_k127_3565378_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000003037 68.0
CMS2_k127_3593834_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 477.0
CMS2_k127_3593834_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 507.0
CMS2_k127_3593834_10 - - - - 0.00000000000000002101 96.0
CMS2_k127_3593834_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003367 284.0
CMS2_k127_3593834_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006984 245.0
CMS2_k127_3593834_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001353 243.0
CMS2_k127_3593834_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000001884 184.0
CMS2_k127_3593834_6 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000005564 116.0
CMS2_k127_3593834_7 MaoC like domain - - - 0.0000000000000000000000001265 106.0
CMS2_k127_3593834_8 Tetratricopeptide repeat - - - 0.00000000000000000000001046 106.0
CMS2_k127_3593834_9 Protein of unknown function (DUF3301) - - - 0.0000000000000000002328 100.0
CMS2_k127_3596599_0 Domain of unknown function (DUF3400) - - - 0.0 1753.0
CMS2_k127_3596599_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 610.0
CMS2_k127_3596599_10 VanZ like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005748 251.0
CMS2_k127_3596599_11 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000000003026 212.0
CMS2_k127_3596599_12 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000008805 210.0
CMS2_k127_3596599_13 Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000001261 216.0
CMS2_k127_3596599_14 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000002866 177.0
CMS2_k127_3596599_15 PFAM histidine triad (HIT) protein - - - 0.000000000000000000000000000000000000000000002749 167.0
CMS2_k127_3596599_16 protein conserved in bacteria K03690 - - 0.00000000000000000000000000003068 125.0
CMS2_k127_3596599_17 - - - - 0.000000000000000000000000004272 115.0
CMS2_k127_3596599_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 574.0
CMS2_k127_3596599_3 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 471.0
CMS2_k127_3596599_4 PFAM ABC transporter related K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 426.0
CMS2_k127_3596599_5 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 409.0
CMS2_k127_3596599_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 356.0
CMS2_k127_3596599_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 351.0
CMS2_k127_3596599_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 332.0
CMS2_k127_3596599_9 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 298.0
CMS2_k127_3676792_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 5.274e-287 891.0
CMS2_k127_3676792_1 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 8.509e-252 786.0
CMS2_k127_3676792_10 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000008199 121.0
CMS2_k127_3676792_11 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000007126 112.0
CMS2_k127_3676792_12 - - - - 0.000000000000003407 83.0
CMS2_k127_3676792_2 Belongs to the malate synthase family K01638 - 2.3.3.9 2.669e-232 729.0
CMS2_k127_3676792_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 1.343e-218 686.0
CMS2_k127_3676792_4 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 419.0
CMS2_k127_3676792_5 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 381.0
CMS2_k127_3676792_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 367.0
CMS2_k127_3676792_7 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000003905 185.0
CMS2_k127_3676792_8 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000002621 162.0
CMS2_k127_3676792_9 PFAM NLP P60 protein - - - 0.0000000000000000000000000000000005268 145.0
CMS2_k127_3704183_0 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 529.0
CMS2_k127_3704183_1 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 347.0
CMS2_k127_3704183_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 314.0
CMS2_k127_3704183_3 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 311.0
CMS2_k127_3704183_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003033 259.0
CMS2_k127_3704183_5 phenazine biosynthesis protein PhzF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001287 271.0
CMS2_k127_3704183_6 Methyltransferase - - - 0.0000000000000000000000000000000000000001931 156.0
CMS2_k127_3704183_7 HxlR-like helix-turn-helix - - - 0.0000000000000000000000003532 109.0
CMS2_k127_3718588_0 mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 343.0
CMS2_k127_3718588_1 glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001143 276.0
CMS2_k127_3718588_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002179 236.0
CMS2_k127_3718588_3 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000004928 164.0
CMS2_k127_3718588_4 - - - - 0.0000000000000000000000000000000007799 134.0
CMS2_k127_3718588_5 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000008901 111.0
CMS2_k127_3718588_6 - - - - 0.000000000000000000209 87.0
CMS2_k127_3825224_0 Histidine kinase-like ATPases K01768,K02488,K17763 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000404 230.0
CMS2_k127_3825224_1 Histidine kinase K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000003402 184.0
CMS2_k127_3872273_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 595.0
CMS2_k127_3872273_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 459.0
CMS2_k127_3872273_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000001254 149.0
CMS2_k127_3872273_11 Transporter associated domain - - - 0.000000000000000000000000000000003233 132.0
CMS2_k127_3872273_12 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000001864 121.0
CMS2_k127_3872273_13 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000002132 89.0
CMS2_k127_3872273_2 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 385.0
CMS2_k127_3872273_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 372.0
CMS2_k127_3872273_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 332.0
CMS2_k127_3872273_5 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000005224 244.0
CMS2_k127_3872273_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000004191 199.0
CMS2_k127_3872273_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000009461 186.0
CMS2_k127_3872273_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000007399 169.0
CMS2_k127_3872273_9 RimM N-terminal domain K02860 - - 0.000000000000000000000000000000000000007754 151.0
CMS2_k127_3916352_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 5e-324 1013.0
CMS2_k127_3916352_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 579.0
CMS2_k127_3916352_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000002391 262.0
CMS2_k127_3916352_11 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000003812 225.0
CMS2_k127_3916352_12 Psort location Cytoplasmic, score 9.97 K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000001162 211.0
CMS2_k127_3916352_13 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000002799 188.0
CMS2_k127_3916352_14 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000002308 172.0
CMS2_k127_3916352_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 431.0
CMS2_k127_3916352_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 392.0
CMS2_k127_3916352_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 388.0
CMS2_k127_3916352_5 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 391.0
CMS2_k127_3916352_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 378.0
CMS2_k127_3916352_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 359.0
CMS2_k127_3916352_8 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 351.0
CMS2_k127_3916352_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007849 268.0
CMS2_k127_3951049_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1564.0
CMS2_k127_3951049_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1181.0
CMS2_k127_3951049_2 COG1180 Pyruvate-formate lyase-activating enzyme K20449 - 1.3.7.1 7.531e-223 697.0
CMS2_k127_3951049_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 3.745e-210 665.0
CMS2_k127_3951049_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 359.0
CMS2_k127_3951049_5 COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase Amino acid transport and metabolism Coenzyme metabolism K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 301.0
CMS2_k127_3951049_6 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007745 291.0
CMS2_k127_3951049_7 Transferase hexapeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000009331 214.0
CMS2_k127_4069413_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 2.396e-286 899.0
CMS2_k127_4069413_1 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.251e-204 650.0
CMS2_k127_4069413_10 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000001352 248.0
CMS2_k127_4069413_11 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) - - - 0.00000000000000000000000000000000000000000000000001623 183.0
CMS2_k127_4069413_12 Preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000000000000008195 146.0
CMS2_k127_4069413_13 tRNA methyl transferase K00566 - 2.8.1.13 0.00000000000000001443 82.0
CMS2_k127_4069413_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.333e-202 640.0
CMS2_k127_4069413_3 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 583.0
CMS2_k127_4069413_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 563.0
CMS2_k127_4069413_5 Queuosine biosynthesis protein K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 410.0
CMS2_k127_4069413_6 HD domain K07814,K13815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 400.0
CMS2_k127_4069413_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 417.0
CMS2_k127_4069413_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 359.0
CMS2_k127_4069413_9 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001598 286.0
CMS2_k127_4088923_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 2.196e-219 689.0
CMS2_k127_4088923_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000003537 216.0
CMS2_k127_4088923_2 Pfam Response regulator receiver - - - 0.00000000000000000000000000000000000000000003418 173.0
CMS2_k127_4088923_3 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000101 108.0
CMS2_k127_4088923_4 response regulator - - - 0.000000000004189 71.0
CMS2_k127_4114126_0 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 325.0
CMS2_k127_4114126_2 Belongs to the peptidase S11 family K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000105 231.0
CMS2_k127_4114126_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000001132 141.0
CMS2_k127_4114126_4 Protein of unknown function (DUF3617) - - - 0.000000000000000002722 97.0
CMS2_k127_4114126_6 - - - - 0.0008496 48.0
CMS2_k127_4114835_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 4.583e-216 679.0
CMS2_k127_4114835_1 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 507.0
CMS2_k127_4114835_10 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000008526 83.0
CMS2_k127_4114835_11 Xylose isomerase-like TIM barrel - - - 0.00000000000003038 74.0
CMS2_k127_4114835_2 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 476.0
CMS2_k127_4114835_3 Cobalamin-independent synthase, Catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 424.0
CMS2_k127_4114835_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 387.0
CMS2_k127_4114835_5 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 379.0
CMS2_k127_4114835_6 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 314.0
CMS2_k127_4114835_7 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001861 248.0
CMS2_k127_4114835_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000004741 192.0
CMS2_k127_4114835_9 ChrR Cupin-like domain - - - 0.00000000000000000000000000000000000000000002082 176.0
CMS2_k127_4153774_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 1.496e-297 931.0
CMS2_k127_4153774_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 2.52e-278 863.0
CMS2_k127_4153774_10 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 456.0
CMS2_k127_4153774_11 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 394.0
CMS2_k127_4153774_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 300.0
CMS2_k127_4153774_13 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000009709 213.0
CMS2_k127_4153774_14 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000000000000001519 151.0
CMS2_k127_4153774_15 Acyl-CoA synthetase (NDP forming) K09181 - - 0.0000000000000000000000000000000008155 141.0
CMS2_k127_4153774_16 Thioesterase superfamily K07107 - - 0.00000000000000000000000000000001351 146.0
CMS2_k127_4153774_17 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000000005324 124.0
CMS2_k127_4153774_2 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.794e-276 867.0
CMS2_k127_4153774_3 Acyl-CoA dehydrogenase N terminal K20035 - - 1.801e-256 803.0
CMS2_k127_4153774_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 7.533e-223 696.0
CMS2_k127_4153774_5 CoA binding domain - - - 8.374e-219 699.0
CMS2_k127_4153774_6 PFAM carboxyl transferase - - - 8.501e-212 670.0
CMS2_k127_4153774_7 homoserine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 490.0
CMS2_k127_4153774_8 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 452.0
CMS2_k127_4153774_9 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 447.0
CMS2_k127_4207499_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1322.0
CMS2_k127_4207499_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.573e-253 786.0
CMS2_k127_4207499_10 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 355.0
CMS2_k127_4207499_11 Permease YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 354.0
CMS2_k127_4207499_12 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007123 265.0
CMS2_k127_4207499_13 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes K03800 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000004786 263.0
CMS2_k127_4207499_14 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000000001557 221.0
CMS2_k127_4207499_15 glycine cleavage K02437 - - 0.0000000000000000000000000000000000000000000000000000000001108 206.0
CMS2_k127_4207499_16 PFAM biotin lipoate A B protein ligase - - - 0.0000000000000000000000000000000000000000000000000001107 203.0
CMS2_k127_4207499_17 DsrE/DsrF-like family K07092 - - 0.0000000000000000000000000000000000000000000000000001709 189.0
CMS2_k127_4207499_18 - - - - 0.000000000000000000000000000000000000000000000000005391 190.0
CMS2_k127_4207499_19 Haem-degrading - - - 0.00000000000000000000000000000000000000000000001654 190.0
CMS2_k127_4207499_2 radical SAM K01012 - 2.8.1.6 4.21e-199 627.0
CMS2_k127_4207499_20 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.000000000000000000000000000000000000001109 157.0
CMS2_k127_4207499_21 - - - - 0.00000000000000000000000000000000000005148 149.0
CMS2_k127_4207499_22 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000002277 135.0
CMS2_k127_4207499_23 - - - - 0.00000000000000000000000000000000222 133.0
CMS2_k127_4207499_24 Protein of unknown function (DUF3106) - - - 0.000000000000000000000000003538 119.0
CMS2_k127_4207499_25 RDD family - - - 0.0000000000000000000000000744 115.0
CMS2_k127_4207499_26 Protein of unknown function (DUF3619) - - - 0.0000000007431 61.0
CMS2_k127_4207499_27 - - - - 0.0006633 48.0
CMS2_k127_4207499_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008939 594.0
CMS2_k127_4207499_4 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 560.0
CMS2_k127_4207499_5 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 548.0
CMS2_k127_4207499_6 SMART Elongator protein 3 MiaB NifB K09711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 482.0
CMS2_k127_4207499_7 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 477.0
CMS2_k127_4207499_8 geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 397.0
CMS2_k127_4207499_9 Permease, YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 387.0
CMS2_k127_4253092_0 Dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 604.0
CMS2_k127_4253092_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 542.0
CMS2_k127_426033_0 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 576.0
CMS2_k127_426033_1 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 490.0
CMS2_k127_426033_10 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000001013 79.0
CMS2_k127_426033_11 DNA-sulfur modification-associated - - - 0.0000205 56.0
CMS2_k127_426033_12 - - - - 0.0003393 47.0
CMS2_k127_426033_2 transport system fused permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 443.0
CMS2_k127_426033_3 With GlrK is part of a two-component signal transduction system regulating glmY K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 442.0
CMS2_k127_426033_4 SMART band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 396.0
CMS2_k127_426033_5 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 359.0
CMS2_k127_426033_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 341.0
CMS2_k127_426033_7 2-Keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001818 241.0
CMS2_k127_426033_8 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000001224 188.0
CMS2_k127_426033_9 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000006419 90.0
CMS2_k127_4279462_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 1.839e-234 738.0
CMS2_k127_4279462_1 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 429.0
CMS2_k127_4279462_2 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 344.0
CMS2_k127_4279462_3 catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 328.0
CMS2_k127_4279462_4 Belongs to the UPF0502 family K09915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 318.0
CMS2_k127_4279462_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000008923 196.0
CMS2_k127_4279462_6 HNH endonuclease - - - 0.00000000000000000003294 93.0
CMS2_k127_4279462_7 - - - - 0.0000000001082 65.0
CMS2_k127_4279462_8 Mediates the transbilayer movement of Und-PP-GlcNAc- ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA) K03328,K16693 - - 0.000001189 61.0
CMS2_k127_4281674_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.164e-269 839.0
CMS2_k127_4281674_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00179 - 1.2.7.8 2.227e-253 793.0
CMS2_k127_4281674_10 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 305.0
CMS2_k127_4281674_11 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 291.0
CMS2_k127_4281674_12 endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002069 302.0
CMS2_k127_4281674_13 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002184 280.0
CMS2_k127_4281674_14 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000001674 245.0
CMS2_k127_4281674_15 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007846 251.0
CMS2_k127_4281674_16 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000000622 198.0
CMS2_k127_4281674_17 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000001225 186.0
CMS2_k127_4281674_18 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000001627 149.0
CMS2_k127_4281674_19 protein conserved in bacteria K09790 - - 0.000000000000000000000000000000004478 137.0
CMS2_k127_4281674_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.453e-199 627.0
CMS2_k127_4281674_20 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.00000000000000000000000000000001788 132.0
CMS2_k127_4281674_21 Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.0000000000000000000000000000002201 128.0
CMS2_k127_4281674_22 PFAM Metallophosphoesterase - - - 0.00000000000000000000000000005644 130.0
CMS2_k127_4281674_26 small protein containing a coiled-coil domain - - - 0.000000001801 63.0
CMS2_k127_4281674_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 580.0
CMS2_k127_4281674_4 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 531.0
CMS2_k127_4281674_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 507.0
CMS2_k127_4281674_6 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 489.0
CMS2_k127_4281674_7 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 446.0
CMS2_k127_4281674_8 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 452.0
CMS2_k127_4281674_9 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 433.0
CMS2_k127_4302673_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008719 281.0
CMS2_k127_4302673_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649,K02594 - 2.3.3.13,2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000009357 235.0
CMS2_k127_4308208_0 enoyl-CoA hydratase K15513 - 4.1.2.44 3.894e-261 814.0
CMS2_k127_4308208_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.005e-258 831.0
CMS2_k127_4308208_2 Shikimate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003903 280.0
CMS2_k127_4308208_3 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000008576 214.0
CMS2_k127_4308208_4 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000007502 180.0
CMS2_k127_4318874_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 3.928e-228 717.0
CMS2_k127_4318874_1 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 507.0
CMS2_k127_4318874_10 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 323.0
CMS2_k127_4318874_11 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 302.0
CMS2_k127_4318874_12 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001285 280.0
CMS2_k127_4318874_13 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002185 286.0
CMS2_k127_4318874_14 pfam abc K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000137 239.0
CMS2_k127_4318874_15 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000001048 218.0
CMS2_k127_4318874_16 NnrU protein - - - 0.00000000000000000000000000000000000000000000001916 186.0
CMS2_k127_4318874_17 Thioesterase - - - 0.0000000000000000000000000000000000000000001522 162.0
CMS2_k127_4318874_18 ArsC family - - - 0.000000000000000000000000000000000001278 147.0
CMS2_k127_4318874_19 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000000002059 140.0
CMS2_k127_4318874_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 509.0
CMS2_k127_4318874_20 aminopeptidase N K01256 - 3.4.11.2 0.00000000000000000001751 92.0
CMS2_k127_4318874_3 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 417.0
CMS2_k127_4318874_4 pfam rok K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 404.0
CMS2_k127_4318874_5 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 384.0
CMS2_k127_4318874_6 Beta-lactamase K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 351.0
CMS2_k127_4318874_7 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 341.0
CMS2_k127_4318874_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 330.0
CMS2_k127_4318874_9 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 327.0
CMS2_k127_4344051_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 6.245e-231 724.0
CMS2_k127_4344051_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 9.363e-196 632.0
CMS2_k127_4344051_10 FAD binding domain K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002115 258.0
CMS2_k127_4344051_11 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000004598 244.0
CMS2_k127_4344051_12 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000001399 214.0
CMS2_k127_4344051_13 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000161 205.0
CMS2_k127_4344051_14 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000001277 105.0
CMS2_k127_4344051_15 - - - - 0.00000000000000000001162 96.0
CMS2_k127_4344051_2 aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 594.0
CMS2_k127_4344051_3 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 554.0
CMS2_k127_4344051_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 467.0
CMS2_k127_4344051_5 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 441.0
CMS2_k127_4344051_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 413.0
CMS2_k127_4344051_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 295.0
CMS2_k127_4344051_8 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 299.0
CMS2_k127_4344051_9 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 258.0
CMS2_k127_4373554_0 Protein of unknown function - - - 7.69e-289 934.0
CMS2_k127_4373554_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 7.244e-222 710.0
CMS2_k127_4384819_0 FAD linked oxidase - - - 4.954e-229 718.0
CMS2_k127_4384819_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 292.0
CMS2_k127_4384819_2 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000004557 250.0
CMS2_k127_4384819_3 SnoaL-like domain - - - 0.000000000000000000000000000000000000004936 150.0
CMS2_k127_4384819_4 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000000000000000000000253 108.0
CMS2_k127_4384819_5 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000008862 59.0
CMS2_k127_4384819_6 ubiE/COQ5 methyltransferase family - - - 0.00001591 47.0
CMS2_k127_4391334_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.914e-296 917.0
CMS2_k127_4391334_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 4.263e-206 648.0
CMS2_k127_4391334_10 3-beta hydroxysteroid dehydrogenase/isomerase family K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 473.0
CMS2_k127_4391334_11 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 465.0
CMS2_k127_4391334_12 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 419.0
CMS2_k127_4391334_13 pfkB family carbohydrate kinase K21344 - 2.7.1.167 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 405.0
CMS2_k127_4391334_14 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 368.0
CMS2_k127_4391334_15 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 322.0
CMS2_k127_4391334_16 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005998 250.0
CMS2_k127_4391334_17 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000005443 239.0
CMS2_k127_4391334_18 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000000002692 169.0
CMS2_k127_4391334_19 Lipopolysaccharide assembly protein A domain K08992 - - 0.000000000000003096 82.0
CMS2_k127_4391334_2 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 1.899e-196 622.0
CMS2_k127_4391334_20 Resolvase, N terminal domain - - - 0.00001494 50.0
CMS2_k127_4391334_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008399 595.0
CMS2_k127_4391334_4 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 541.0
CMS2_k127_4391334_5 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 528.0
CMS2_k127_4391334_6 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 520.0
CMS2_k127_4391334_7 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 510.0
CMS2_k127_4391334_8 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 503.0
CMS2_k127_4391334_9 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 479.0
CMS2_k127_4439445_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1508.0
CMS2_k127_4439445_1 aminopeptidase N K01256 - 3.4.11.2 0.0 1032.0
CMS2_k127_4439445_2 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 554.0
CMS2_k127_4439445_3 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 546.0
CMS2_k127_4439445_4 toluene tolerance family protein K07323 - - 0.0000000000000000000000000000000000000000000000001688 184.0
CMS2_k127_4568248_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 8.169e-233 740.0
CMS2_k127_4568248_1 AMP-binding enzyme K12508 - 6.2.1.34 3.681e-220 709.0
CMS2_k127_4568248_10 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 299.0
CMS2_k127_4568248_11 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000285 251.0
CMS2_k127_4568248_12 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000009484 217.0
CMS2_k127_4568248_13 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000003143 203.0
CMS2_k127_4568248_14 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000000000000001592 184.0
CMS2_k127_4568248_15 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000007442 171.0
CMS2_k127_4568248_16 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000004868 148.0
CMS2_k127_4568248_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000006264 116.0
CMS2_k127_4568248_18 (Lipo)protein - - - 0.0000000000008992 76.0
CMS2_k127_4568248_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 437.0
CMS2_k127_4568248_3 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 403.0
CMS2_k127_4568248_4 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 390.0
CMS2_k127_4568248_5 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 357.0
CMS2_k127_4568248_6 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 354.0
CMS2_k127_4568248_7 Chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 348.0
CMS2_k127_4568248_8 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 328.0
CMS2_k127_4568248_9 Preprotein translocase subunit TatD K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 313.0
CMS2_k127_4573672_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 9.956e-291 913.0
CMS2_k127_4573672_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 9.475e-261 816.0
CMS2_k127_4573672_10 COG0739 Membrane proteins related to metalloendopeptidases K06194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002074 250.0
CMS2_k127_4573672_11 PFAM Lytic transglycosylase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000005571 237.0
CMS2_k127_4573672_12 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000003892 196.0
CMS2_k127_4573672_13 PFAM regulatory protein, MerR - - - 0.000000000000000000000000000000000000000000000000005218 183.0
CMS2_k127_4573672_14 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000009697 177.0
CMS2_k127_4573672_15 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000001844 169.0
CMS2_k127_4573672_16 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000002074 91.0
CMS2_k127_4573672_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 550.0
CMS2_k127_4573672_3 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 533.0
CMS2_k127_4573672_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 361.0
CMS2_k127_4573672_5 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 306.0
CMS2_k127_4573672_6 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 287.0
CMS2_k127_4573672_7 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001722 279.0
CMS2_k127_4573672_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000002182 270.0
CMS2_k127_4573672_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003809 258.0
CMS2_k127_4618396_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1439.0
CMS2_k127_4618396_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.566e-283 879.0
CMS2_k127_4618396_10 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002921 267.0
CMS2_k127_4618396_11 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000051 213.0
CMS2_k127_4618396_12 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.0000000000000000000000000000000000000000000000000000000001918 218.0
CMS2_k127_4618396_13 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000001158 203.0
CMS2_k127_4618396_14 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000002009 206.0
CMS2_k127_4618396_15 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000001598 196.0
CMS2_k127_4618396_16 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000002293 196.0
CMS2_k127_4618396_17 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000001294 192.0
CMS2_k127_4618396_18 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000001628 199.0
CMS2_k127_4618396_19 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000004614 153.0
CMS2_k127_4618396_2 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 6.538e-265 834.0
CMS2_k127_4618396_20 Protein of unknown function (DUF3015) - - - 0.000000000000000000000000000000000003863 143.0
CMS2_k127_4618396_21 Ribonuclease K01167 - 3.1.27.3 0.000000000000000000000000000000000005813 140.0
CMS2_k127_4618396_22 Putative regulatory protein - - - 0.000000000000000000000000001852 117.0
CMS2_k127_4618396_23 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000005975 117.0
CMS2_k127_4618396_24 Periplasmic binding protein domain K01999 - - 0.000000000000000000000002342 106.0
CMS2_k127_4618396_25 (Barnase) inhibitor - - - 0.0000000000000000000005675 105.0
CMS2_k127_4618396_26 Sodium Bile acid symporter family - - - 0.0000000000000000008304 92.0
CMS2_k127_4618396_3 SbmA/BacA-like family K02471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 572.0
CMS2_k127_4618396_4 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 426.0
CMS2_k127_4618396_5 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 427.0
CMS2_k127_4618396_6 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 386.0
CMS2_k127_4618396_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 357.0
CMS2_k127_4618396_8 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 321.0
CMS2_k127_4618396_9 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 305.0
CMS2_k127_4705065_0 Circularly permuted ATP-grasp type 2 - - - 1.495e-314 984.0
CMS2_k127_4705065_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.162e-224 718.0
CMS2_k127_4705065_2 Circularly permuted ATP-grasp type 2 - - - 2.225e-220 692.0
CMS2_k127_4705065_3 Bacterial transglutaminase-like N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 354.0
CMS2_k127_4705065_4 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 351.0
CMS2_k127_4705065_5 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 321.0
CMS2_k127_4705065_6 transglutaminase - - - 0.000000000000000000000000000000000000000000000000000001119 213.0
CMS2_k127_4705065_7 Enoyl-CoA hydratase/isomerase - - - 0.00000000000003901 72.0
CMS2_k127_4707_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 3.06e-322 998.0
CMS2_k127_4707_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.416e-292 908.0
CMS2_k127_4707_10 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 384.0
CMS2_k127_4707_11 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 395.0
CMS2_k127_4707_12 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 340.0
CMS2_k127_4707_13 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 349.0
CMS2_k127_4707_14 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 327.0
CMS2_k127_4707_15 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 317.0
CMS2_k127_4707_16 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 308.0
CMS2_k127_4707_17 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 309.0
CMS2_k127_4707_18 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 284.0
CMS2_k127_4707_19 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009124 286.0
CMS2_k127_4707_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 2.679e-200 641.0
CMS2_k127_4707_20 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000169 275.0
CMS2_k127_4707_21 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001136 246.0
CMS2_k127_4707_22 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000001706 248.0
CMS2_k127_4707_23 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000000000000002166 202.0
CMS2_k127_4707_24 Hydrolase, P-loop family K06925 - - 0.0000000000000000000000000000000000000000000000009344 178.0
CMS2_k127_4707_25 Biopolymer transport protein K03559 - - 0.00000000000000000000000000000000000007524 152.0
CMS2_k127_4707_26 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000267 121.0
CMS2_k127_4707_27 - - - - 0.000000000000000000000000002041 113.0
CMS2_k127_4707_29 - - - - 0.0000000000000000005727 94.0
CMS2_k127_4707_3 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 552.0
CMS2_k127_4707_30 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000001694 90.0
CMS2_k127_4707_31 Helix-turn-helix domain - - - 0.000000000001138 70.0
CMS2_k127_4707_32 protein containing LysM domain - - - 0.0000001569 64.0
CMS2_k127_4707_33 COG0835 Chemotaxis signal transduction protein K03408 - - 0.00001771 57.0
CMS2_k127_4707_34 - - - - 0.00001975 47.0
CMS2_k127_4707_35 - - - - 0.000023 51.0
CMS2_k127_4707_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 569.0
CMS2_k127_4707_5 PFAM Rieske 2Fe-2S K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 509.0
CMS2_k127_4707_6 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 493.0
CMS2_k127_4707_7 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 449.0
CMS2_k127_4707_8 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 417.0
CMS2_k127_4707_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 418.0
CMS2_k127_471506_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 604.0
CMS2_k127_471506_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 596.0
CMS2_k127_471506_10 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007065 289.0
CMS2_k127_471506_11 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001662 283.0
CMS2_k127_471506_12 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001744 253.0
CMS2_k127_471506_13 COG0725 ABC-type molybdate transport system, periplasmic component K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009789 255.0
CMS2_k127_471506_14 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000000000001767 231.0
CMS2_k127_471506_15 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000003742 231.0
CMS2_k127_471506_16 PBP superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000004666 235.0
CMS2_k127_471506_17 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000009474 164.0
CMS2_k127_471506_18 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000151 114.0
CMS2_k127_471506_19 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000002744 119.0
CMS2_k127_471506_2 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 509.0
CMS2_k127_471506_20 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000001348 110.0
CMS2_k127_471506_21 - - - - 0.000000000004216 68.0
CMS2_k127_471506_3 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 397.0
CMS2_k127_471506_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 380.0
CMS2_k127_471506_5 Bacterial extracellular solute-binding protein K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 371.0
CMS2_k127_471506_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 343.0
CMS2_k127_471506_7 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 303.0
CMS2_k127_471506_8 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 295.0
CMS2_k127_471506_9 Binding-protein-dependent transport system inner membrane component K02018 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 287.0
CMS2_k127_4730711_0 MMPL family - - - 0.0 1301.0
CMS2_k127_4730711_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 7.47e-202 640.0
CMS2_k127_4730711_10 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 308.0
CMS2_k127_4730711_11 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001965 280.0
CMS2_k127_4730711_12 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000006088 231.0
CMS2_k127_4730711_13 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000001592 200.0
CMS2_k127_4730711_14 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000004459 186.0
CMS2_k127_4730711_15 CRP FNR family K21563 - - 0.000000000000000000000000000000000000000007703 163.0
CMS2_k127_4730711_16 FixH K09926 - - 0.00000000000000000000000000000000000001169 154.0
CMS2_k127_4730711_17 Universal stress protein - - - 0.000000000000000000000000000000008802 133.0
CMS2_k127_4730711_18 Invasion gene expression up-regulator SirB - - - 0.00000000000000000000000000003118 121.0
CMS2_k127_4730711_19 - - - - 0.000000000000000000000000335 115.0
CMS2_k127_4730711_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 597.0
CMS2_k127_4730711_20 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.000000000000000000000002627 108.0
CMS2_k127_4730711_21 - - - - 0.000000000000000000005083 98.0
CMS2_k127_4730711_22 Pfam Response regulator receiver - - - 0.0000000000000000003871 93.0
CMS2_k127_4730711_23 Heavy metal transport detoxification protein K07213 - - 0.000000000000007071 76.0
CMS2_k127_4730711_24 - - - - 0.0000000000002333 82.0
CMS2_k127_4730711_25 Cytochrome c - - - 0.00000005498 61.0
CMS2_k127_4730711_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 591.0
CMS2_k127_4730711_4 RNA-metabolising metallo-beta-lactamase K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 540.0
CMS2_k127_4730711_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 374.0
CMS2_k127_4730711_6 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 353.0
CMS2_k127_4730711_7 DnaJ C terminal domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 351.0
CMS2_k127_4730711_8 Divalent cation transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 325.0
CMS2_k127_4730711_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 306.0
CMS2_k127_4807083_0 PFAM carboxyl transferase K01615 - 4.1.1.70 8.273e-294 910.0
CMS2_k127_4807083_1 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 564.0
CMS2_k127_4807083_2 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 378.0
CMS2_k127_4807083_3 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 368.0
CMS2_k127_4807083_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.0000000000000000000000000000000002421 145.0
CMS2_k127_4807083_5 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000002897 108.0
CMS2_k127_4807083_6 Biotin-requiring enzyme - - - 0.000000000000000000001286 95.0
CMS2_k127_4809060_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1577.0
CMS2_k127_4809060_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 298.0
CMS2_k127_4809060_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002708 271.0
CMS2_k127_4809060_3 Chaperone - - - 0.0000000000000000000000000000000000000000000000005581 189.0
CMS2_k127_4809060_4 - - - - 0.00000000000000000000000000000000000000000004555 183.0
CMS2_k127_4809060_5 - - - - 0.000001023 60.0
CMS2_k127_4809060_6 - - - - 0.00002981 54.0
CMS2_k127_482260_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 6.492e-240 776.0
CMS2_k127_482260_1 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 393.0
CMS2_k127_482260_2 chemotaxis K03406,K05875 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 357.0
CMS2_k127_482260_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 323.0
CMS2_k127_482260_4 Phenylacetic acid degradation protein PaaY K02617,K08279 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 288.0
CMS2_k127_482260_5 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000001354 265.0
CMS2_k127_482260_6 Cache_2 - - - 0.00000000000000000000000000000000000000000000000000000000003573 211.0
CMS2_k127_482260_7 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000009419 213.0
CMS2_k127_4834753_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.661e-220 690.0
CMS2_k127_4834753_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 535.0
CMS2_k127_4834753_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 347.0
CMS2_k127_4834753_11 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 336.0
CMS2_k127_4834753_12 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 329.0
CMS2_k127_4834753_13 LrgB-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 320.0
CMS2_k127_4834753_14 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 288.0
CMS2_k127_4834753_15 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002907 278.0
CMS2_k127_4834753_16 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000005499 224.0
CMS2_k127_4834753_17 - - - - 0.00000000000000000000000000000000000000000004447 170.0
CMS2_k127_4834753_18 LrgA family K06518 - - 0.000000000000000000000000000000001721 132.0
CMS2_k127_4834753_19 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000007577 134.0
CMS2_k127_4834753_2 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 458.0
CMS2_k127_4834753_20 VanZ like family - - - 0.0000000000000000000381 104.0
CMS2_k127_4834753_21 Protein of unknown function (DUF1161) - - - 0.00000000000000002931 86.0
CMS2_k127_4834753_23 Protein of unknown function (DUF3567) - - - 0.00000000000002991 76.0
CMS2_k127_4834753_24 Protein of unknown function (DUF3617) - - - 0.0002915 49.0
CMS2_k127_4834753_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 423.0
CMS2_k127_4834753_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 401.0
CMS2_k127_4834753_5 PFAM alanine racemase domain protein K19967 - 4.1.2.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 427.0
CMS2_k127_4834753_6 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 377.0
CMS2_k127_4834753_7 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 374.0
CMS2_k127_4834753_8 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 351.0
CMS2_k127_4834753_9 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008726 354.0
CMS2_k127_4863182_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 319.0
CMS2_k127_4863182_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 293.0
CMS2_k127_4863182_2 EamA-like transporter family - - - 0.0000000000001773 73.0
CMS2_k127_4913355_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.8e-210 661.0
CMS2_k127_4913355_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 541.0
CMS2_k127_4913355_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 458.0
CMS2_k127_4913355_3 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 324.0
CMS2_k127_4913355_4 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009982 273.0
CMS2_k127_4913355_5 synthesis repressor, PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000009241 231.0
CMS2_k127_4913355_6 - - - - 0.00000000000001725 78.0
CMS2_k127_4937504_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 357.0
CMS2_k127_4937504_1 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000003511 220.0
CMS2_k127_4967813_0 Tripartite tricarboxylate transporter TctA family K07793 - - 5.399e-217 683.0
CMS2_k127_4967813_1 alkaline phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 533.0
CMS2_k127_4967813_10 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001659 229.0
CMS2_k127_4967813_11 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000006881 217.0
CMS2_k127_4967813_12 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000067 161.0
CMS2_k127_4967813_13 DUF218 domain - - - 0.00000000000000000000000000000000000006389 152.0
CMS2_k127_4967813_14 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000000000000000000005272 110.0
CMS2_k127_4967813_15 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000009024 72.0
CMS2_k127_4967813_16 Domain of unknown function (DUF4340) - - - 0.000000000007934 77.0
CMS2_k127_4967813_2 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 445.0
CMS2_k127_4967813_3 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 420.0
CMS2_k127_4967813_4 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 362.0
CMS2_k127_4967813_5 PFAM conserved K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 352.0
CMS2_k127_4967813_6 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 349.0
CMS2_k127_4967813_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 317.0
CMS2_k127_4967813_8 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 299.0
CMS2_k127_4967813_9 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008551 284.0
CMS2_k127_5039345_0 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 539.0
CMS2_k127_5039345_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 395.0
CMS2_k127_5039345_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 347.0
CMS2_k127_5039345_3 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000817 242.0
CMS2_k127_5039345_4 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000103 234.0
CMS2_k127_5039345_5 transport system small permease component - - - 0.000000000000000000000000000000000000000000000001469 180.0
CMS2_k127_5055478_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1690.0
CMS2_k127_5055478_1 dna topoisomerase III K03169 - 5.99.1.2 1.112e-260 812.0
CMS2_k127_5055478_10 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 408.0
CMS2_k127_5055478_11 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 379.0
CMS2_k127_5055478_12 PFAM Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 354.0
CMS2_k127_5055478_13 KR domain K07535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 345.0
CMS2_k127_5055478_14 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 344.0
CMS2_k127_5055478_15 AMP-binding enzyme C-terminal domain K04110,K20458 - 6.2.1.25,6.2.1.27,6.2.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 351.0
CMS2_k127_5055478_16 maleylacetoacetate isomerase K01801 - 5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 291.0
CMS2_k127_5055478_17 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001023 281.0
CMS2_k127_5055478_18 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 283.0
CMS2_k127_5055478_19 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000001516 230.0
CMS2_k127_5055478_2 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 4.119e-218 700.0
CMS2_k127_5055478_20 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000107 210.0
CMS2_k127_5055478_21 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000001007 202.0
CMS2_k127_5055478_22 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000000000001868 183.0
CMS2_k127_5055478_23 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000004332 145.0
CMS2_k127_5055478_24 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000001633 136.0
CMS2_k127_5055478_25 diguanylate cyclase - - - 0.000000000000000000001364 108.0
CMS2_k127_5055478_26 Thioesterase-like superfamily - - - 0.0000000000000000003964 102.0
CMS2_k127_5055478_27 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000001807 68.0
CMS2_k127_5055478_28 cobalamin synthesis protein, P47K - GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0008270,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000576 68.0
CMS2_k127_5055478_3 ammonium transporter K03320 - - 3.913e-214 674.0
CMS2_k127_5055478_4 PFAM TrkA-N domain protein K03499 - - 3.808e-202 638.0
CMS2_k127_5055478_5 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 609.0
CMS2_k127_5055478_6 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 597.0
CMS2_k127_5055478_7 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 492.0
CMS2_k127_5055478_8 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 471.0
CMS2_k127_5055478_9 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 418.0
CMS2_k127_5088057_0 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 587.0
CMS2_k127_5088057_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 556.0
CMS2_k127_5088057_10 - - - - 0.000000000000000000000006038 113.0
CMS2_k127_5088057_12 - - - - 0.00000000000003338 76.0
CMS2_k127_5088057_2 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 531.0
CMS2_k127_5088057_3 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 541.0
CMS2_k127_5088057_4 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 498.0
CMS2_k127_5088057_5 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 497.0
CMS2_k127_5088057_6 Tat pathway signal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 432.0
CMS2_k127_5088057_7 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000001477 188.0
CMS2_k127_5088057_8 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.000000000000000000000000000000000000000000000001013 176.0
CMS2_k127_5088057_9 B12 binding domain - - - 0.00000000000000000000000000000003576 136.0
CMS2_k127_5089335_0 Bifunctional transglycosylase second domain K05365 - 2.4.1.129,3.4.16.4 2.099e-283 891.0
CMS2_k127_5089335_1 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 6.127e-236 747.0
CMS2_k127_5089335_10 - - - - 0.000000000000000000000000000000000008165 140.0
CMS2_k127_5089335_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000003556 133.0
CMS2_k127_5089335_12 Hypoxia induced protein conserved region - - - 0.0001307 48.0
CMS2_k127_5089335_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 564.0
CMS2_k127_5089335_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 496.0
CMS2_k127_5089335_4 Amidohydrolase K10220 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 452.0
CMS2_k127_5089335_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 388.0
CMS2_k127_5089335_6 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K04108 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000007761 265.0
CMS2_k127_5089335_7 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000005143 209.0
CMS2_k127_5089335_8 Glutathione peroxidase K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000002714 214.0
CMS2_k127_5089335_9 Flavodoxin K06205 - - 0.000000000000000000000000000000000001369 141.0
CMS2_k127_5104771_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 8.553e-313 971.0
CMS2_k127_5104771_1 Dehydratase family K13875 - 4.2.1.25 1.355e-309 966.0
CMS2_k127_5104771_10 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 493.0
CMS2_k127_5104771_11 Belongs to the ABC transporter superfamily K02010,K10112 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 483.0
CMS2_k127_5104771_12 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 489.0
CMS2_k127_5104771_13 PFAM AAA ATPase central domain protein K06413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 457.0
CMS2_k127_5104771_14 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 425.0
CMS2_k127_5104771_15 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 413.0
CMS2_k127_5104771_16 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 354.0
CMS2_k127_5104771_17 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 349.0
CMS2_k127_5104771_18 Enoyl-(Acyl carrier protein) reductase K21883 - 1.1.1.401 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 340.0
CMS2_k127_5104771_19 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 329.0
CMS2_k127_5104771_2 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.261e-277 858.0
CMS2_k127_5104771_20 Transcriptional regulator K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 329.0
CMS2_k127_5104771_21 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 309.0
CMS2_k127_5104771_22 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001416 246.0
CMS2_k127_5104771_23 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000001195 232.0
CMS2_k127_5104771_24 subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000000003596 221.0
CMS2_k127_5104771_25 FCD - - - 0.000000000000000000000000000000000000000000000000000001934 208.0
CMS2_k127_5104771_3 Bacterial extracellular solute-binding protein K02027 - - 1.279e-216 678.0
CMS2_k127_5104771_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 1.779e-201 638.0
CMS2_k127_5104771_5 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 572.0
CMS2_k127_5104771_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 536.0
CMS2_k127_5104771_7 TIGRFAM amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 540.0
CMS2_k127_5104771_8 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 526.0
CMS2_k127_5104771_9 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 515.0
CMS2_k127_5113799_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 4.025e-217 700.0
CMS2_k127_5113799_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.327e-198 624.0
CMS2_k127_5113799_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 514.0
CMS2_k127_5113799_3 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 499.0
CMS2_k127_5113799_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 488.0
CMS2_k127_5113799_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 473.0
CMS2_k127_5113799_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 418.0
CMS2_k127_5113799_7 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 400.0
CMS2_k127_5113799_8 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 377.0
CMS2_k127_5113799_9 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000000000000000000006956 224.0
CMS2_k127_5197745_0 ABC transporter - - - 4.676e-286 886.0
CMS2_k127_5197745_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 4.774e-201 641.0
CMS2_k127_5197745_2 chemotaxis K03406,K03776,K05875 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 366.0
CMS2_k127_5197745_3 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000001553 235.0
CMS2_k127_5197745_4 phosphorelay sensor kinase activity K02342,K02851 - 2.7.7.7,2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000004984 215.0
CMS2_k127_5197745_5 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000005256 168.0
CMS2_k127_5241208_0 Hydantoinase/oxoprolinase - - - 1.596e-298 928.0
CMS2_k127_5241208_1 Hydantoinase B/oxoprolinase - - - 2.11e-197 621.0
CMS2_k127_5241208_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 297.0
CMS2_k127_5241208_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000001213 190.0
CMS2_k127_5245191_0 Polysaccharide biosynthesis protein - - - 1.206e-228 733.0
CMS2_k127_5245191_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 2.899e-217 698.0
CMS2_k127_5245191_10 Bacterial sugar transferase K13012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005087 281.0
CMS2_k127_5245191_11 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000001106 208.0
CMS2_k127_5245191_12 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000000006853 134.0
CMS2_k127_5245191_13 - - - - 0.000000000000001218 80.0
CMS2_k127_5245191_14 - - - - 0.000000006902 59.0
CMS2_k127_5245191_2 TonB dependent receptor K02014 - - 9.269e-205 660.0
CMS2_k127_5245191_3 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 595.0
CMS2_k127_5245191_4 PFAM glycosyl transferase family 9 K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 451.0
CMS2_k127_5245191_5 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 396.0
CMS2_k127_5245191_6 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 413.0
CMS2_k127_5245191_7 Glycosyltransferase Family 4 K02844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 351.0
CMS2_k127_5245191_8 Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 297.0
CMS2_k127_5245191_9 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 302.0
CMS2_k127_5290333_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1028.0
CMS2_k127_5290333_1 Lipoprotein-releasing system permease protein K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 559.0
CMS2_k127_5290333_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 555.0
CMS2_k127_5290333_3 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000003384 138.0
CMS2_k127_5304305_0 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 562.0
CMS2_k127_5304305_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 446.0
CMS2_k127_5304305_10 Ribosomal L28 family K02902 - - 0.00000000000000000000000000001707 119.0
CMS2_k127_5304305_11 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000001345 110.0
CMS2_k127_5304305_12 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000008616 96.0
CMS2_k127_5304305_13 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000003174 70.0
CMS2_k127_5304305_2 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 372.0
CMS2_k127_5304305_3 Membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 355.0
CMS2_k127_5304305_4 tRNA synthetases class I (E and Q), catalytic domain K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 341.0
CMS2_k127_5304305_5 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 302.0
CMS2_k127_5304305_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002523 271.0
CMS2_k127_5304305_7 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000003518 186.0
CMS2_k127_5304305_8 - - - - 0.000000000000000000000000000000000001447 145.0
CMS2_k127_5304305_9 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000005858 131.0
CMS2_k127_5313090_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 2436.0
CMS2_k127_5313090_1 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000002257 181.0
CMS2_k127_5313090_2 regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000002097 179.0
CMS2_k127_5313090_3 PFAM Methionine synthase vitamin-B12 independent K00549 - 2.1.1.14 0.0000000007718 63.0
CMS2_k127_5324359_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 3.734e-284 889.0
CMS2_k127_5324359_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 607.0
CMS2_k127_5324359_10 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000003846 168.0
CMS2_k127_5324359_11 branched-chain amino acid K01995 - - 0.00000000000000000000000000000000000000001447 154.0
CMS2_k127_5324359_12 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000001803 151.0
CMS2_k127_5324359_13 Cupin 2, conserved barrel domain protein K21700 - - 0.000000000000000000000000000001351 124.0
CMS2_k127_5324359_14 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000003283 130.0
CMS2_k127_5324359_15 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000002322 116.0
CMS2_k127_5324359_16 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0001163 51.0
CMS2_k127_5324359_2 PFAM Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 428.0
CMS2_k127_5324359_3 Hpt domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 426.0
CMS2_k127_5324359_4 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 359.0
CMS2_k127_5324359_5 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 303.0
CMS2_k127_5324359_6 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001167 263.0
CMS2_k127_5324359_7 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000001348 209.0
CMS2_k127_5324359_8 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000002629 198.0
CMS2_k127_5324359_9 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000005605 183.0
CMS2_k127_5339239_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 5.353e-237 742.0
CMS2_k127_5339239_1 Ferrous iron transport protein B K04759 - - 7.237e-237 753.0
CMS2_k127_5339239_10 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000003591 151.0
CMS2_k127_5339239_11 Thioesterase superfamily protein - - - 0.0000000000000000000003958 102.0
CMS2_k127_5339239_13 Major Facilitator Superfamily - - - 0.00000000000001849 77.0
CMS2_k127_5339239_16 Dienelactone hydrolase family - - - 0.00001186 57.0
CMS2_k127_5339239_2 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 7.316e-219 700.0
CMS2_k127_5339239_3 Aldehyde dehydrogenase K00128,K00130 - 1.2.1.3,1.2.1.8 3.897e-209 665.0
CMS2_k127_5339239_4 FAD binding domain K07077 - - 1.812e-206 682.0
CMS2_k127_5339239_5 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 509.0
CMS2_k127_5339239_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 374.0
CMS2_k127_5339239_7 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 367.0
CMS2_k127_5339239_8 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 320.0
CMS2_k127_5339239_9 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000002351 209.0
CMS2_k127_5351652_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.69e-216 686.0
CMS2_k127_5351652_1 Spermine/spermidine synthase domain - - - 1.152e-199 645.0
CMS2_k127_5351652_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 584.0
CMS2_k127_5351652_3 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 513.0
CMS2_k127_5351652_4 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 428.0
CMS2_k127_5351652_5 PFAM Methionine biosynthesis MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006257 275.0
CMS2_k127_5351652_6 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000000000000000000000000000000000003156 183.0
CMS2_k127_5351652_7 - - - - 0.000000000000000000000000000000000000008526 159.0
CMS2_k127_5351652_8 Phosphotransferase System K11189 - - 0.000000000000000000000000000000000001806 139.0
CMS2_k127_5351652_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000005112 106.0
CMS2_k127_5374929_0 TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA K03694 - - 0.0 1175.0
CMS2_k127_5374929_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 7.744e-231 719.0
CMS2_k127_5374929_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 316.0
CMS2_k127_5374929_11 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004056 274.0
CMS2_k127_5374929_12 glycolate oxidase iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000001272 236.0
CMS2_k127_5374929_13 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000009043 227.0
CMS2_k127_5374929_14 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000006888 168.0
CMS2_k127_5374929_15 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000009675 160.0
CMS2_k127_5374929_16 Cold shock K03704 - - 0.0000000000000000000000000000000001054 134.0
CMS2_k127_5374929_17 cytochrome - - - 0.000000000000000000001352 98.0
CMS2_k127_5374929_2 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 2.483e-230 723.0
CMS2_k127_5374929_3 STAS domain K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 621.0
CMS2_k127_5374929_4 COG0471 Di- and tricarboxylate transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 564.0
CMS2_k127_5374929_5 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 505.0
CMS2_k127_5374929_6 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 447.0
CMS2_k127_5374929_7 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 445.0
CMS2_k127_5374929_8 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 418.0
CMS2_k127_5374929_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 400.0
CMS2_k127_5388281_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1017.0
CMS2_k127_5388281_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000004772 198.0
CMS2_k127_5388281_2 permease - - - 0.0000000000000000000000000000005545 135.0
CMS2_k127_5392513_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 335.0
CMS2_k127_5392513_1 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000006616 243.0
CMS2_k127_5392513_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000004753 226.0
CMS2_k127_5392513_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000008488 182.0
CMS2_k127_5392513_4 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000001303 140.0
CMS2_k127_5420923_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 477.0
CMS2_k127_5420923_1 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 448.0
CMS2_k127_5420923_2 Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 312.0
CMS2_k127_5420923_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007608 245.0
CMS2_k127_5420923_4 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000006587 184.0
CMS2_k127_5420923_5 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000004978 138.0
CMS2_k127_5420923_6 integral membrane protein K07027 - - 0.000000000005186 75.0
CMS2_k127_5471245_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1334.0
CMS2_k127_5471245_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1022.0
CMS2_k127_5471245_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 367.0
CMS2_k127_5471245_11 Nicotinamidase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 319.0
CMS2_k127_5471245_12 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001098 270.0
CMS2_k127_5471245_13 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001024 264.0
CMS2_k127_5471245_14 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000002264 252.0
CMS2_k127_5471245_15 Conserved TM helix - - - 0.00000000000000000000000000000000000000000000000000000000000000002379 232.0
CMS2_k127_5471245_16 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000004369 248.0
CMS2_k127_5471245_17 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000001245 216.0
CMS2_k127_5471245_19 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000008094 170.0
CMS2_k127_5471245_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1007.0
CMS2_k127_5471245_20 Prokaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000132 153.0
CMS2_k127_5471245_21 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000002964 160.0
CMS2_k127_5471245_22 protein conserved in bacteria - - - 0.0000001196 64.0
CMS2_k127_5471245_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.665e-250 804.0
CMS2_k127_5471245_4 Exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 536.0
CMS2_k127_5471245_5 Psort location Cytoplasmic, score 7.50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 522.0
CMS2_k127_5471245_6 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 500.0
CMS2_k127_5471245_7 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 464.0
CMS2_k127_5471245_8 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 468.0
CMS2_k127_5471245_9 Amino Acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 383.0
CMS2_k127_5526490_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K00170 - 1.2.7.1 4.52e-316 987.0
CMS2_k127_5526490_1 FtsX-like permease family K02004 - - 8.003e-249 802.0
CMS2_k127_5526490_10 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 411.0
CMS2_k127_5526490_11 Rhodanese Homology Domain K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 402.0
CMS2_k127_5526490_12 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 398.0
CMS2_k127_5526490_13 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 373.0
CMS2_k127_5526490_14 Peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 374.0
CMS2_k127_5526490_15 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 297.0
CMS2_k127_5526490_16 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002744 286.0
CMS2_k127_5526490_17 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001626 276.0
CMS2_k127_5526490_18 ferredoxin K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001112 280.0
CMS2_k127_5526490_19 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000002071 225.0
CMS2_k127_5526490_2 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 3.418e-203 644.0
CMS2_k127_5526490_20 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000000000001866 205.0
CMS2_k127_5526490_21 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000003612 172.0
CMS2_k127_5526490_22 lipid carrier protein - - - 0.0000000000000000000000000000001963 129.0
CMS2_k127_5526490_23 maltose operon periplasmic K05775 - - 0.0000000000000006009 87.0
CMS2_k127_5526490_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 559.0
CMS2_k127_5526490_4 Peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 520.0
CMS2_k127_5526490_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 506.0
CMS2_k127_5526490_6 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 520.0
CMS2_k127_5526490_7 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 514.0
CMS2_k127_5526490_8 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 450.0
CMS2_k127_5526490_9 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 417.0
CMS2_k127_557976_0 TIGRFAM cytochrome c-type biogenesis protein CcmF K02198 - - 1.056e-305 952.0
CMS2_k127_557976_1 Fumarate reductase flavoprotein C-term - - - 1.339e-253 794.0
CMS2_k127_557976_10 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000001778 219.0
CMS2_k127_557976_11 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000001232 214.0
CMS2_k127_557976_12 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000001827 156.0
CMS2_k127_557976_13 Fumarate reductase subunit C - - - 0.000000000000000000000000004665 124.0
CMS2_k127_557976_14 Fumarate reductase subunit D - - - 0.000000000000000000002833 102.0
CMS2_k127_557976_15 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000002353 69.0
CMS2_k127_557976_16 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000000008652 64.0
CMS2_k127_557976_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 393.0
CMS2_k127_557976_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 389.0
CMS2_k127_557976_4 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 348.0
CMS2_k127_557976_5 Cytochrome c-type biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 305.0
CMS2_k127_557976_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004156 277.0
CMS2_k127_557976_7 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007591 273.0
CMS2_k127_557976_8 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000004489 249.0
CMS2_k127_557976_9 Transcriptional regulator, Crp Fnr family K21563 - - 0.000000000000000000000000000000000000000000000000000000000000001429 225.0
CMS2_k127_5680684_0 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 402.0
CMS2_k127_5680684_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002552 273.0
CMS2_k127_5680684_2 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000001205 168.0
CMS2_k127_5680684_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000001044 89.0
CMS2_k127_5693543_0 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 346.0
CMS2_k127_5693543_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000008698 201.0
CMS2_k127_5702628_0 Diguanylate cyclase - - - 2.336e-224 708.0
CMS2_k127_5702628_1 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 581.0
CMS2_k127_5702628_10 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000000004505 216.0
CMS2_k127_5702628_11 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000000001328 204.0
CMS2_k127_5702628_12 cheY-homologous receiver domain K02485 - - 0.00000000000000000000000000000000000000000000000000000009513 201.0
CMS2_k127_5702628_13 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000151 198.0
CMS2_k127_5702628_14 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000008662 164.0
CMS2_k127_5702628_15 PKD domain K19668 - 3.2.1.91 0.0000000000000000000000000001597 126.0
CMS2_k127_5702628_16 Protein of unknown function (DUF504) - - - 0.0000000000000000000000002548 112.0
CMS2_k127_5702628_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 411.0
CMS2_k127_5702628_3 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 347.0
CMS2_k127_5702628_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 339.0
CMS2_k127_5702628_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 332.0
CMS2_k127_5702628_6 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
CMS2_k127_5702628_7 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005161 258.0
CMS2_k127_5702628_8 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000395 230.0
CMS2_k127_5702628_9 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000000000000000001501 225.0
CMS2_k127_5801571_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 1.926e-202 635.0
CMS2_k127_5801571_1 poly(R)-hydroxyalkanoic acid synthase K03821 - - 2.135e-202 648.0
CMS2_k127_5801571_10 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000002772 233.0
CMS2_k127_5801571_11 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000004667 183.0
CMS2_k127_5801571_12 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000001835 181.0
CMS2_k127_5801571_13 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000002925 167.0
CMS2_k127_5801571_14 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000003196 153.0
CMS2_k127_5801571_15 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000006127 150.0
CMS2_k127_5801571_16 thiolester hydrolase activity K17362 - - 0.0000000000000000000000000000001134 130.0
CMS2_k127_5801571_17 Protein of unknown function (DUF1289) K06938 - - 0.0000000000007249 77.0
CMS2_k127_5801571_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 617.0
CMS2_k127_5801571_3 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 511.0
CMS2_k127_5801571_4 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 504.0
CMS2_k127_5801571_5 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 522.0
CMS2_k127_5801571_6 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 456.0
CMS2_k127_5801571_7 branched-chain amino acid K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 447.0
CMS2_k127_5801571_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 366.0
CMS2_k127_5801571_9 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 303.0
CMS2_k127_5818010_0 protein synthesis factor, GTP-binding K06207 - - 1.022e-292 910.0
CMS2_k127_5818010_1 PFAM AMP-dependent synthetase K01895 - 6.2.1.1 2.667e-257 808.0
CMS2_k127_5818010_10 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 514.0
CMS2_k127_5818010_11 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 504.0
CMS2_k127_5818010_12 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 484.0
CMS2_k127_5818010_13 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 464.0
CMS2_k127_5818010_14 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 428.0
CMS2_k127_5818010_15 pdz dhr glgf - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 433.0
CMS2_k127_5818010_16 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 402.0
CMS2_k127_5818010_17 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 396.0
CMS2_k127_5818010_18 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 382.0
CMS2_k127_5818010_19 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 385.0
CMS2_k127_5818010_2 Aldehyde dehydrogenase family K21802 - 1.2.1.67 2.233e-256 797.0
CMS2_k127_5818010_20 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 380.0
CMS2_k127_5818010_21 RNA polymerase sigma K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 365.0
CMS2_k127_5818010_22 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 352.0
CMS2_k127_5818010_23 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 336.0
CMS2_k127_5818010_24 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 342.0
CMS2_k127_5818010_25 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 329.0
CMS2_k127_5818010_26 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 320.0
CMS2_k127_5818010_27 Branched-chain amino acid transport K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007891 290.0
CMS2_k127_5818010_28 cell division K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003274 284.0
CMS2_k127_5818010_29 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003717 279.0
CMS2_k127_5818010_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.294e-242 752.0
CMS2_k127_5818010_30 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002839 253.0
CMS2_k127_5818010_31 Ribosomal L25p family K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008519 252.0
CMS2_k127_5818010_32 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002852 259.0
CMS2_k127_5818010_33 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000001845 241.0
CMS2_k127_5818010_34 oxidase assembly K02258 - - 0.00000000000000000000000000000000000000000000000000000000000000000008014 241.0
CMS2_k127_5818010_35 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000009888 236.0
CMS2_k127_5818010_36 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000477 231.0
CMS2_k127_5818010_37 DNA replication, recombination, and repair K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000001825 200.0
CMS2_k127_5818010_38 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000000006686 187.0
CMS2_k127_5818010_39 signal sequence binding - - - 0.0000000000000000000000000000000000000000000002661 175.0
CMS2_k127_5818010_4 Peptidase M1 membrane alanine aminopeptidase - - - 1.144e-237 758.0
CMS2_k127_5818010_40 Outer membrane lipoprotein LolB - - - 0.000000000000000000000000000000000000000008977 163.0
CMS2_k127_5818010_41 2Fe-2S iron-sulfur cluster binding domain K03863 - - 0.00000000000000000000000000000000001587 141.0
CMS2_k127_5818010_42 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000005774 109.0
CMS2_k127_5818010_43 Protein of unknown function (DUF2909) - - - 0.0000000000000000002228 90.0
CMS2_k127_5818010_44 Protein of unknown function (DUF2970) - - - 0.000127 51.0
CMS2_k127_5818010_5 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 6.433e-234 735.0
CMS2_k127_5818010_6 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 1.921e-216 684.0
CMS2_k127_5818010_7 Receptor family ligand binding region - - - 3.179e-209 658.0
CMS2_k127_5818010_8 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 562.0
CMS2_k127_5818010_9 Flotillin K07192 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 547.0
CMS2_k127_5890921_0 ABC transporter - - - 1.196e-235 746.0
CMS2_k127_5890921_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 2.575e-218 692.0
CMS2_k127_5890921_10 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K05586 - 1.6.5.3 0.00000000000000000000000000000007831 134.0
CMS2_k127_5890921_11 SMART Cold shock protein K03704 - - 0.00000000000000000000000000000192 120.0
CMS2_k127_5890921_12 Ribonuclease B OB domain K03704 - - 0.0000000000000000000000000001794 115.0
CMS2_k127_5890921_13 Thioredoxin domain - - - 0.0000000000000000000003692 97.0
CMS2_k127_5890921_2 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 442.0
CMS2_k127_5890921_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 362.0
CMS2_k127_5890921_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 349.0
CMS2_k127_5890921_5 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 332.0
CMS2_k127_5890921_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 308.0
CMS2_k127_5890921_7 TIGRFAM SagB-type dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002048 254.0
CMS2_k127_5890921_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000002049 163.0
CMS2_k127_5890921_9 DGC domain - - - 0.0000000000000000000000000000000000000001604 156.0
CMS2_k127_5913542_0 Cytochrome c554 and c-prime - - - 3.721e-241 764.0
CMS2_k127_5913542_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 3.415e-204 666.0
CMS2_k127_5913542_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 304.0
CMS2_k127_5913542_11 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001394 286.0
CMS2_k127_5913542_12 response regulator K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008264 264.0
CMS2_k127_5913542_13 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000009419 204.0
CMS2_k127_5913542_14 cytochrome c5 - - - 0.00000000000000000000000000000000000000000000006881 184.0
CMS2_k127_5913542_15 - - - - 0.00000000000000000000000000000000000000000000007815 178.0
CMS2_k127_5913542_16 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000001551 167.0
CMS2_k127_5913542_17 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000003293 146.0
CMS2_k127_5913542_18 - - - - 0.000000000000000000000001674 117.0
CMS2_k127_5913542_19 Cytochrome c - - - 0.000000000000000000000003995 116.0
CMS2_k127_5913542_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 562.0
CMS2_k127_5913542_20 PFAM Cytochrome C - - - 0.000000000000000000000008174 113.0
CMS2_k127_5913542_21 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000005177 102.0
CMS2_k127_5913542_22 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000004396 109.0
CMS2_k127_5913542_23 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.0000000000000001976 91.0
CMS2_k127_5913542_24 cytochrome - - - 0.000000000008154 77.0
CMS2_k127_5913542_25 COG2863 Cytochrome c553 - - - 0.00000000007884 74.0
CMS2_k127_5913542_26 cytochrome - - - 0.0000004955 62.0
CMS2_k127_5913542_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 535.0
CMS2_k127_5913542_4 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 399.0
CMS2_k127_5913542_5 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 377.0
CMS2_k127_5913542_6 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 349.0
CMS2_k127_5913542_7 cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 336.0
CMS2_k127_5913542_8 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 329.0
CMS2_k127_5913542_9 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 318.0
CMS2_k127_5939099_0 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 521.0
CMS2_k127_5939099_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 309.0
CMS2_k127_5939099_2 EamA-like transporter family - - - 0.0000000000000000000000000000000004865 140.0
CMS2_k127_5959004_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 7.901e-259 829.0
CMS2_k127_5959004_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.198e-245 764.0
CMS2_k127_5959004_10 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 514.0
CMS2_k127_5959004_11 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 423.0
CMS2_k127_5959004_12 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 441.0
CMS2_k127_5959004_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 391.0
CMS2_k127_5959004_14 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 380.0
CMS2_k127_5959004_15 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 368.0
CMS2_k127_5959004_16 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 360.0
CMS2_k127_5959004_17 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 348.0
CMS2_k127_5959004_18 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 352.0
CMS2_k127_5959004_19 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 317.0
CMS2_k127_5959004_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 4.236e-226 704.0
CMS2_k127_5959004_20 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 318.0
CMS2_k127_5959004_21 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007149 268.0
CMS2_k127_5959004_22 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003873 276.0
CMS2_k127_5959004_23 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000005912 250.0
CMS2_k127_5959004_24 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000108 262.0
CMS2_k127_5959004_25 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000003749 257.0
CMS2_k127_5959004_26 type 4 pilus biogenesis protein K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000008474 241.0
CMS2_k127_5959004_27 [2Fe-2S] binding domain K18029 - 1.17.2.1 0.0000000000000000000000000000000000000000000000000000000000000005056 222.0
CMS2_k127_5959004_28 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000009237 200.0
CMS2_k127_5959004_29 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000000000003976 138.0
CMS2_k127_5959004_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 6.471e-203 639.0
CMS2_k127_5959004_30 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000004939 96.0
CMS2_k127_5959004_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 576.0
CMS2_k127_5959004_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 554.0
CMS2_k127_5959004_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 551.0
CMS2_k127_5959004_7 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 546.0
CMS2_k127_5959004_8 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 526.0
CMS2_k127_5959004_9 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 520.0
CMS2_k127_5985142_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.6e-211 663.0
CMS2_k127_5985142_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 587.0
CMS2_k127_5985142_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 308.0
CMS2_k127_5985142_11 Cytochrome C1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 287.0
CMS2_k127_5985142_12 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002061 275.0
CMS2_k127_5985142_13 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000004918 204.0
CMS2_k127_5985142_14 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000000000002538 168.0
CMS2_k127_5985142_15 Stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000103 156.0
CMS2_k127_5985142_16 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.0000000000000000000000000000000001047 144.0
CMS2_k127_5985142_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000007444 119.0
CMS2_k127_5985142_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000002002 104.0
CMS2_k127_5985142_2 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 484.0
CMS2_k127_5985142_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 411.0
CMS2_k127_5985142_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 404.0
CMS2_k127_5985142_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 376.0
CMS2_k127_5985142_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 340.0
CMS2_k127_5985142_7 Glutathione S-transferase K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 334.0
CMS2_k127_5985142_8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 334.0
CMS2_k127_5985142_9 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 347.0
CMS2_k127_6000236_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.48e-306 963.0
CMS2_k127_6000236_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 9.174e-288 893.0
CMS2_k127_6000236_10 Fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001637 270.0
CMS2_k127_6000236_11 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001446 263.0
CMS2_k127_6000236_12 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004622 257.0
CMS2_k127_6000236_13 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000006944 226.0
CMS2_k127_6000236_14 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000634 219.0
CMS2_k127_6000236_15 PFAM OsmC family protein K04063 - - 0.0000000000000000000000000000000000000000000000001621 182.0
CMS2_k127_6000236_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.771e-237 740.0
CMS2_k127_6000236_3 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 548.0
CMS2_k127_6000236_4 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 486.0
CMS2_k127_6000236_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 473.0
CMS2_k127_6000236_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 447.0
CMS2_k127_6000236_7 His Kinase A (phosphoacceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 451.0
CMS2_k127_6000236_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 323.0
CMS2_k127_6000236_9 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 331.0
CMS2_k127_6006697_0 AMP-binding enzyme C-terminal domain K00666 - - 3.33e-231 725.0
CMS2_k127_6006697_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 571.0
CMS2_k127_6006697_10 ABC transporter - - - 0.00000000000000000000006497 104.0
CMS2_k127_6006697_2 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 495.0
CMS2_k127_6006697_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 472.0
CMS2_k127_6006697_4 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 357.0
CMS2_k127_6006697_5 Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006594 269.0
CMS2_k127_6006697_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000007791 215.0
CMS2_k127_6006697_7 Permease MlaE - - - 0.0000000000000000000000000000000000000000000000000003069 197.0
CMS2_k127_6006697_8 - - - - 0.00000000000000000000000000000000000000000005649 180.0
CMS2_k127_6006697_9 - - - - 0.000000000000000000000001781 110.0
CMS2_k127_6017979_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.207e-268 838.0
CMS2_k127_6017979_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 590.0
CMS2_k127_6017979_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002564 284.0
CMS2_k127_6017979_3 OmpA-like transmembrane domain - - - 0.000006478 59.0
CMS2_k127_6026591_0 DNA polymerase X family K02347 - - 3.422e-252 790.0
CMS2_k127_6026591_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 6.799e-210 665.0
CMS2_k127_6026591_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 307.0
CMS2_k127_6026591_3 homoserine dehydrogenase - - - 0.00000000000000000000000000000000000000000000004123 172.0
CMS2_k127_6026591_4 4-carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000003902 190.0
CMS2_k127_603023_0 elongation factor G K02355 - - 2.826e-289 904.0
CMS2_k127_603023_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 2.414e-202 635.0
CMS2_k127_603023_10 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000000000000000000000000000000000000000000000000000000001554 220.0
CMS2_k127_603023_11 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000000000000007028 176.0
CMS2_k127_603023_12 MgtC family K07507 - - 0.00000000000000000000000000000000000002711 155.0
CMS2_k127_603023_13 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000001035 144.0
CMS2_k127_603023_14 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000000003014 128.0
CMS2_k127_603023_15 - - - - 0.00000000000001168 76.0
CMS2_k127_603023_2 Universal stress protein family K07090 - - 5.243e-198 636.0
CMS2_k127_603023_3 Protein of unknown function (DUF993) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 567.0
CMS2_k127_603023_4 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 469.0
CMS2_k127_603023_5 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 404.0
CMS2_k127_603023_6 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 334.0
CMS2_k127_603023_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 317.0
CMS2_k127_603023_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001334 270.0
CMS2_k127_603023_9 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000008342 228.0
CMS2_k127_6065478_0 Insulinase (Peptidase family M16) K07263 - - 1.748e-272 865.0
CMS2_k127_6065478_1 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 351.0
CMS2_k127_6065478_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001931 248.0
CMS2_k127_6065478_3 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000000000000000000000000005219 194.0
CMS2_k127_6065478_4 branched-chain amino acid - - - 0.0000000000007601 79.0
CMS2_k127_6096751_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 589.0
CMS2_k127_6096751_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 422.0
CMS2_k127_6096751_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 400.0
CMS2_k127_6096751_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 376.0
CMS2_k127_6096751_4 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 356.0
CMS2_k127_6096751_5 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.000000000000000000000000000000000000000000001159 168.0
CMS2_k127_6109694_0 Thi4 family - - - 4.923e-206 653.0
CMS2_k127_6109694_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 536.0
CMS2_k127_6109694_10 transcriptional regulator - - - 0.000000000000000000000000000000002571 139.0
CMS2_k127_6109694_11 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000007512 121.0
CMS2_k127_6109694_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 398.0
CMS2_k127_6109694_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 388.0
CMS2_k127_6109694_4 branched-chain amino acid transport K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 321.0
CMS2_k127_6109694_5 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 308.0
CMS2_k127_6109694_6 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005675 252.0
CMS2_k127_6109694_7 Thioesterase - - - 0.00000000000000000000000000000000000000000000251 168.0
CMS2_k127_6109694_8 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000002049 161.0
CMS2_k127_6109694_9 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000008014 144.0
CMS2_k127_6136673_0 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 503.0
CMS2_k127_6136673_1 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 398.0
CMS2_k127_6136673_2 protein conserved in bacteria K09937 - - 0.00000000005611 63.0
CMS2_k127_6170071_0 acyl-CoA dehydrogenase K06445 - - 1.817e-309 1000.0
CMS2_k127_6170071_1 ABC transporter transmembrane region K06147 - - 6.938e-238 759.0
CMS2_k127_6170071_10 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000005163 224.0
CMS2_k127_6170071_11 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000009998 126.0
CMS2_k127_6170071_12 Dodecin K09165 - - 0.000000000000000000000008865 102.0
CMS2_k127_6170071_2 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.825e-219 694.0
CMS2_k127_6170071_3 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 613.0
CMS2_k127_6170071_4 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 588.0
CMS2_k127_6170071_5 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 352.0
CMS2_k127_6170071_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 336.0
CMS2_k127_6170071_7 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 310.0
CMS2_k127_6170071_8 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001293 278.0
CMS2_k127_6170071_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000002777 239.0
CMS2_k127_6194348_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1266.0
CMS2_k127_6194348_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 574.0
CMS2_k127_6194348_10 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001245 250.0
CMS2_k127_6194348_11 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000001776 239.0
CMS2_k127_6194348_12 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000000000000000000000000000000001649 235.0
CMS2_k127_6194348_13 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000001725 204.0
CMS2_k127_6194348_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000002044 194.0
CMS2_k127_6194348_15 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000008548 177.0
CMS2_k127_6194348_2 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 516.0
CMS2_k127_6194348_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 510.0
CMS2_k127_6194348_4 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 434.0
CMS2_k127_6194348_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 435.0
CMS2_k127_6194348_6 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 402.0
CMS2_k127_6194348_7 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 409.0
CMS2_k127_6194348_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 329.0
CMS2_k127_6194348_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001974 299.0
CMS2_k127_6195552_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.003e-308 958.0
CMS2_k127_6195552_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 9.03e-301 933.0
CMS2_k127_6195552_10 Ammonia monooxygenase K07120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001406 274.0
CMS2_k127_6195552_11 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000004709 214.0
CMS2_k127_6195552_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000004969 188.0
CMS2_k127_6195552_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000004615 180.0
CMS2_k127_6195552_14 ATP synthase B/B' CF(0) K02109 - - 0.00000000000000000000000000000000000000000000006996 174.0
CMS2_k127_6195552_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000006312 133.0
CMS2_k127_6195552_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.08e-274 851.0
CMS2_k127_6195552_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.327e-264 824.0
CMS2_k127_6195552_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 426.0
CMS2_k127_6195552_5 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009158 367.0
CMS2_k127_6195552_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 357.0
CMS2_k127_6195552_7 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 357.0
CMS2_k127_6195552_8 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 346.0
CMS2_k127_6195552_9 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 311.0
CMS2_k127_6223440_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1125.0
CMS2_k127_6223440_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0 1098.0
CMS2_k127_6223440_10 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 450.0
CMS2_k127_6223440_11 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 434.0
CMS2_k127_6223440_12 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 357.0
CMS2_k127_6223440_13 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 345.0
CMS2_k127_6223440_14 glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 356.0
CMS2_k127_6223440_15 (FHA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 314.0
CMS2_k127_6223440_16 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 310.0
CMS2_k127_6223440_17 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001746 270.0
CMS2_k127_6223440_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004932 260.0
CMS2_k127_6223440_19 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000004626 218.0
CMS2_k127_6223440_2 Belongs to the TPP enzyme family K01577 - 4.1.1.8 6.288e-316 975.0
CMS2_k127_6223440_20 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000002932 169.0
CMS2_k127_6223440_21 Tfp pilus assembly protein, major pilin PilA K02650 - - 0.0000000000000000000000000000000000000003289 154.0
CMS2_k127_6223440_22 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000008797 138.0
CMS2_k127_6223440_23 membrane protein (DUF2079) - - - 0.00000000000000000000000000001549 136.0
CMS2_k127_6223440_24 - - - - 0.000000000000000147 93.0
CMS2_k127_6223440_25 Condensation domain K04788,K12239 GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006518,GO:0006629,GO:0006631,GO:0006633,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009267,GO:0009405,GO:0009605,GO:0009607,GO:0009712,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0016053,GO:0018958,GO:0019184,GO:0019290,GO:0019540,GO:0019725,GO:0019748,GO:0019752,GO:0019842,GO:0030003,GO:0030312,GO:0031177,GO:0031667,GO:0031668,GO:0031669,GO:0032787,GO:0033218,GO:0033554,GO:0034641,GO:0036094,GO:0042592,GO:0042594,GO:0043043,GO:0043167,GO:0043168,GO:0043207,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0044550,GO:0044620,GO:0046394,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051188,GO:0051192,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0075136,GO:0098771,GO:0140104,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901615 - 0.0000001383 62.0
CMS2_k127_6223440_3 CHASE2 K01768 - 4.6.1.1 2.645e-280 880.0
CMS2_k127_6223440_4 Tripartite tricarboxylate transporter TctA family K07793 - - 1.145e-243 760.0
CMS2_k127_6223440_5 metal-dependent phosphohydrolase HD sub domain - - - 1.233e-240 755.0
CMS2_k127_6223440_6 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 581.0
CMS2_k127_6223440_7 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 559.0
CMS2_k127_6223440_8 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 465.0
CMS2_k127_6223440_9 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 441.0
CMS2_k127_6240070_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 591.0
CMS2_k127_6240070_1 UPF0313 protein - - - 0.0000000000000000000000000000000000000000000000000000000000001201 213.0
CMS2_k127_6240070_2 Protein of unknown function (DUF2817) - - - 0.0000000000000000000000000000000000000000000941 174.0
CMS2_k127_6240070_3 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000005731 151.0
CMS2_k127_6240070_4 Cell wall hydrolyses involved in spore germination - - - 0.000000000000000000000000009323 116.0
CMS2_k127_6240070_5 - - - - 0.00000000000000001309 85.0
CMS2_k127_6240070_6 - - - - 0.0001479 46.0
CMS2_k127_6284830_0 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1418.0
CMS2_k127_6284830_1 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 6.116e-215 673.0
CMS2_k127_6284830_2 formate dehydrogenase K00122 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 336.0
CMS2_k127_633337_0 Diguanylate cyclase - - - 3.268e-311 982.0
CMS2_k127_633337_1 Histidine kinase K05962 - 2.7.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 445.0
CMS2_k127_633337_10 MaoC like domain - - - 0.0000000000000000000000000000000000000000000001612 185.0
CMS2_k127_633337_11 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000007037 167.0
CMS2_k127_633337_12 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000009941 153.0
CMS2_k127_633337_13 Nudix hydrolase - - - 0.000000000000000000000000000000000000007078 160.0
CMS2_k127_633337_14 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000003549 144.0
CMS2_k127_633337_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 406.0
CMS2_k127_633337_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 400.0
CMS2_k127_633337_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 347.0
CMS2_k127_633337_5 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 289.0
CMS2_k127_633337_6 Protein of unknown function (DUF3750) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002065 280.0
CMS2_k127_633337_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006033 274.0
CMS2_k127_633337_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001476 270.0
CMS2_k127_633337_9 PFAM Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000003157 269.0
CMS2_k127_634216_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1266.0
CMS2_k127_634216_1 DNA helicase K03657 - 3.6.4.12 9.388e-305 950.0
CMS2_k127_634216_10 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001344 295.0
CMS2_k127_634216_11 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001168 257.0
CMS2_k127_634216_12 Peptidase C13 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001141 263.0
CMS2_k127_634216_13 SMART Signal transduction response regulator, receiver region - - - 0.000000000000000000000000000000000000000000000000000002672 196.0
CMS2_k127_634216_14 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000001124 164.0
CMS2_k127_634216_15 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000000000008253 147.0
CMS2_k127_634216_16 Diguanylate cyclase - - - 0.0000000000000000000000000000000000004083 161.0
CMS2_k127_634216_17 membrane - - - 0.0000000000000000000000000000000000004828 143.0
CMS2_k127_634216_18 Membrane protein YqjD - GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0043021,GO:0043024,GO:0044464,GO:0044877,GO:0060187,GO:0071944 - 0.000000000008643 72.0
CMS2_k127_634216_2 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 3.144e-251 794.0
CMS2_k127_634216_20 Putative Actinobacterial Holin-X, holin superfamily III - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00002046 53.0
CMS2_k127_634216_21 Protein of unknown function (DUF2905) - - - 0.00004633 46.0
CMS2_k127_634216_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 7.373e-239 748.0
CMS2_k127_634216_4 Diguanylate cyclase - - - 2.613e-213 687.0
CMS2_k127_634216_5 transglycosylase K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 492.0
CMS2_k127_634216_6 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 442.0
CMS2_k127_634216_7 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 359.0
CMS2_k127_634216_8 epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 324.0
CMS2_k127_634216_9 Integral membrane sensor signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 327.0
CMS2_k127_6364627_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 1.766e-284 883.0
CMS2_k127_6364627_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.957e-214 680.0
CMS2_k127_6364627_10 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 325.0
CMS2_k127_6364627_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000001119 215.0
CMS2_k127_6364627_12 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000005266 165.0
CMS2_k127_6364627_13 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000007321 128.0
CMS2_k127_6364627_14 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000000003122 96.0
CMS2_k127_6364627_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 573.0
CMS2_k127_6364627_3 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 453.0
CMS2_k127_6364627_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 453.0
CMS2_k127_6364627_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 456.0
CMS2_k127_6364627_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 383.0
CMS2_k127_6364627_7 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 351.0
CMS2_k127_6364627_8 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K22229 - 1.1.1.215 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 346.0
CMS2_k127_6364627_9 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 333.0
CMS2_k127_6379013_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.482e-231 733.0
CMS2_k127_6379013_1 Alkaline and neutral invertase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 444.0
CMS2_k127_6379013_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 424.0
CMS2_k127_6379013_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 355.0
CMS2_k127_6379013_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 310.0
CMS2_k127_6379013_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000004157 242.0
CMS2_k127_6379013_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000009848 123.0
CMS2_k127_6379013_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000008206 70.0
CMS2_k127_6379013_8 - - - - 0.00000000001935 68.0
CMS2_k127_644045_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.782e-222 699.0
CMS2_k127_644045_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 6.434e-214 673.0
CMS2_k127_644045_2 Rod shape-determining protein MreB K03569 - - 8.44e-198 619.0
CMS2_k127_644045_3 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 483.0
CMS2_k127_644045_4 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 378.0
CMS2_k127_644045_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 345.0
CMS2_k127_644045_6 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002968 276.0
CMS2_k127_644045_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000339 119.0
CMS2_k127_644045_8 - - - - 0.0000000000000000001273 97.0
CMS2_k127_6460187_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 486.0
CMS2_k127_6460187_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 414.0
CMS2_k127_6460187_2 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 398.0
CMS2_k127_6460187_3 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000000008711 216.0
CMS2_k127_646149_0 Molecular chaperone. Has ATPase activity K04079 - - 1.411e-295 919.0
CMS2_k127_646149_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 3.492e-254 796.0
CMS2_k127_646149_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003844 240.0
CMS2_k127_646149_11 catechol 1,2-dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000005093 219.0
CMS2_k127_646149_12 Belongs to the CinA family - - - 0.0000000000000000000000000000000000000000000000000001491 189.0
CMS2_k127_646149_13 Disulfide bond formation protein DsbB K03611 - - 0.00000000000000000000000000000000000000000817 170.0
CMS2_k127_646149_14 Catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000002331 90.0
CMS2_k127_646149_15 Glycine zipper - - - 0.000000000000000002144 94.0
CMS2_k127_646149_16 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000002189 83.0
CMS2_k127_646149_2 FtsX-like permease family K02004 - - 5.036e-232 746.0
CMS2_k127_646149_3 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 535.0
CMS2_k127_646149_4 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 519.0
CMS2_k127_646149_5 Chitin synthase K14666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 484.0
CMS2_k127_646149_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 434.0
CMS2_k127_646149_7 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 409.0
CMS2_k127_646149_8 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 291.0
CMS2_k127_646149_9 Putative heavy-metal chelation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 295.0
CMS2_k127_6536700_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 391.0
CMS2_k127_6536700_1 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 324.0
CMS2_k127_6536700_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001211 237.0
CMS2_k127_6536700_3 Protein of unknown function (DUF2905) - - - 0.0000000000003643 71.0
CMS2_k127_6548169_0 heat shock protein binding - - - 9.163e-201 639.0
CMS2_k127_6548169_1 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 541.0
CMS2_k127_6548169_10 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000002993 151.0
CMS2_k127_6548169_11 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000000000000000007731 147.0
CMS2_k127_6548169_12 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000001384 64.0
CMS2_k127_6548169_13 Sulfite exporter TauE/SafE K07090 - - 0.000001166 50.0
CMS2_k127_6548169_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 374.0
CMS2_k127_6548169_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000266 286.0
CMS2_k127_6548169_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001422 288.0
CMS2_k127_6548169_5 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000003925 232.0
CMS2_k127_6548169_6 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000003412 210.0
CMS2_k127_6548169_7 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000005464 218.0
CMS2_k127_6548169_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000004885 199.0
CMS2_k127_6548169_9 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000001235 187.0
CMS2_k127_661735_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 5.23e-248 779.0
CMS2_k127_661735_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 615.0
CMS2_k127_661735_10 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.00000000000000000000000000000000003888 146.0
CMS2_k127_661735_11 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.000000000000000000000000003317 126.0
CMS2_k127_661735_12 Permeases of the major facilitator superfamily - - - 0.000000000000000000001763 100.0
CMS2_k127_661735_2 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 612.0
CMS2_k127_661735_3 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 486.0
CMS2_k127_661735_4 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 320.0
CMS2_k127_661735_5 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003302 296.0
CMS2_k127_661735_6 Nitrile hydratase K01721,K20807 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000001777 257.0
CMS2_k127_661735_7 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000009496 192.0
CMS2_k127_661735_8 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000001277 173.0
CMS2_k127_661735_9 Chromate transporter K07240 - - 0.0000000000000000000000000000000000008204 147.0
CMS2_k127_6680576_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1615.0
CMS2_k127_6680576_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 4.863e-230 725.0
CMS2_k127_6680576_10 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000000000000000000000001898 215.0
CMS2_k127_6680576_11 - - - - 0.000000000000000000000000000000000000000000000000000000001571 215.0
CMS2_k127_6680576_12 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000002317 187.0
CMS2_k127_6680576_13 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000001001 130.0
CMS2_k127_6680576_14 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000000002566 125.0
CMS2_k127_6680576_15 Rubredoxin - - - 0.00000000000000000000000000009189 115.0
CMS2_k127_6680576_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000001624 127.0
CMS2_k127_6680576_17 PFAM Cysteine-rich - - - 0.00000000007634 64.0
CMS2_k127_6680576_2 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 1.612e-205 651.0
CMS2_k127_6680576_3 Aminotransferase K09758 - 4.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 566.0
CMS2_k127_6680576_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 408.0
CMS2_k127_6680576_5 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 378.0
CMS2_k127_6680576_6 Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 349.0
CMS2_k127_6680576_7 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 321.0
CMS2_k127_6680576_8 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001083 245.0
CMS2_k127_6680576_9 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001169 248.0
CMS2_k127_6682718_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 571.0
CMS2_k127_6682718_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 520.0
CMS2_k127_6682718_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 518.0
CMS2_k127_6682718_3 Mediates influx of magnesium ions K03284,K16074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 449.0
CMS2_k127_6682718_4 PFAM aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 397.0
CMS2_k127_6682718_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 359.0
CMS2_k127_6682718_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001732 247.0
CMS2_k127_6682718_7 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000001428 189.0
CMS2_k127_6682718_8 Transcriptional regulator - - - 0.000000000101 70.0
CMS2_k127_6682718_9 - - - - 0.0000000002832 65.0
CMS2_k127_6686408_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 549.0
CMS2_k127_6686408_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 493.0
CMS2_k127_6686408_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 378.0
CMS2_k127_6686408_3 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 381.0
CMS2_k127_6686408_4 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 343.0
CMS2_k127_6686408_5 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003938 287.0
CMS2_k127_6686408_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000007128 265.0
CMS2_k127_6686408_7 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000477 224.0
CMS2_k127_6686408_8 Protein of unknown function (DUF3305) - - - 0.00000000000000000009772 97.0
CMS2_k127_6700273_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 7.614e-314 971.0
CMS2_k127_6700273_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.375e-250 781.0
CMS2_k127_6700273_10 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003806 265.0
CMS2_k127_6700273_11 Acetolactate synthase small K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000007006 257.0
CMS2_k127_6700273_12 Acyltransferase - - - 0.000000000000000000000000000000000000000000000004271 179.0
CMS2_k127_6700273_13 Predicted membrane protein (DUF2069) - - - 0.0000000000000000000000000000000000001126 149.0
CMS2_k127_6700273_14 Domain of unknown function (DUF4396) - - - 0.0000000000000005877 80.0
CMS2_k127_6700273_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 579.0
CMS2_k127_6700273_3 Na+ dependent nucleoside transporter N-terminus K03317 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 483.0
CMS2_k127_6700273_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 347.0
CMS2_k127_6700273_5 protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 330.0
CMS2_k127_6700273_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 299.0
CMS2_k127_6700273_7 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001371 283.0
CMS2_k127_6700273_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002028 287.0
CMS2_k127_6700273_9 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004796 282.0
CMS2_k127_6730766_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.666e-277 869.0
CMS2_k127_6730766_1 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 4.536e-229 718.0
CMS2_k127_6730766_10 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006522 266.0
CMS2_k127_6730766_11 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001433 245.0
CMS2_k127_6730766_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000863 224.0
CMS2_k127_6730766_13 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000005751 207.0
CMS2_k127_6730766_14 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000008473 204.0
CMS2_k127_6730766_15 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000001218 140.0
CMS2_k127_6730766_16 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000001031 132.0
CMS2_k127_6730766_17 - - - - 0.000000000000000000000000002716 113.0
CMS2_k127_6730766_18 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000000001828 94.0
CMS2_k127_6730766_19 protein conserved in bacteria K09937 - - 0.0000000000000000005871 87.0
CMS2_k127_6730766_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.113e-217 696.0
CMS2_k127_6730766_20 HflC and HflK could regulate a protease K04087 - - 0.0000000005797 60.0
CMS2_k127_6730766_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 7.134e-196 631.0
CMS2_k127_6730766_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 529.0
CMS2_k127_6730766_5 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 528.0
CMS2_k127_6730766_6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 434.0
CMS2_k127_6730766_7 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 426.0
CMS2_k127_6730766_8 Alpha beta hydrolase K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 372.0
CMS2_k127_6730766_9 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 305.0
CMS2_k127_673690_0 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000255 275.0
CMS2_k127_673690_1 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000001002 164.0
CMS2_k127_673690_2 TRAP-type C4-dicarboxylate transport system, large permease component K11690 GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015556,GO:0015711,GO:0015740,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000007338 151.0
CMS2_k127_673690_3 deoxyhypusine monooxygenase activity - - - 0.00051 51.0
CMS2_k127_6761740_0 SNARE associated Golgi protein - - - 0.0 1057.0
CMS2_k127_6761740_1 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 381.0
CMS2_k127_6761740_2 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 328.0
CMS2_k127_6761740_3 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 306.0
CMS2_k127_6761740_4 Glycosyl transferase group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000359 270.0
CMS2_k127_6761740_5 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000006708 220.0
CMS2_k127_6761740_6 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000009154 162.0
CMS2_k127_6761740_7 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000004865 166.0
CMS2_k127_6761740_8 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000008568 131.0
CMS2_k127_6773735_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1254.0
CMS2_k127_6773735_1 type II secretion system protein K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 606.0
CMS2_k127_6773735_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000004612 234.0
CMS2_k127_6773735_11 DNA gyrase inhibitor YacG - - - 0.00000000000000001782 84.0
CMS2_k127_6773735_12 Protein of unknown function (DUF721) - - - 0.00000002298 62.0
CMS2_k127_6773735_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 527.0
CMS2_k127_6773735_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 453.0
CMS2_k127_6773735_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 388.0
CMS2_k127_6773735_5 General function prediction only K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 393.0
CMS2_k127_6773735_6 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 342.0
CMS2_k127_6773735_7 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 334.0
CMS2_k127_6773735_8 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 328.0
CMS2_k127_6773735_9 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 327.0
CMS2_k127_6793324_0 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.768e-235 744.0
CMS2_k127_6793324_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 558.0
CMS2_k127_6793324_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000006426 252.0
CMS2_k127_6793324_3 Thioesterase superfamily protein K10806 - - 0.0000000000000000000000000000000000000001103 154.0
CMS2_k127_6793324_4 MltA-interacting MipA family protein K07274 - - 0.00000000000006301 81.0
CMS2_k127_6811725_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 1.678e-194 618.0
CMS2_k127_6811725_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 417.0
CMS2_k127_6811725_2 3-Deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 420.0
CMS2_k127_6811725_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 350.0
CMS2_k127_6811725_4 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 317.0
CMS2_k127_6811725_5 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008039 284.0
CMS2_k127_6811725_6 Protein of unknown function (DUF4254) - - - 0.00000000000000000000000000000000000000000000000000000000000004609 219.0
CMS2_k127_6811725_7 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000002521 217.0
CMS2_k127_6811725_8 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000009975 131.0
CMS2_k127_6811725_9 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0006343 43.0
CMS2_k127_6876944_0 Domain of unknown function (DUF3394) - - - 0.0 1287.0
CMS2_k127_6876944_1 Translation, ribosomal structure and biogenesis K08301 - - 1.021e-232 728.0
CMS2_k127_6876944_10 methyl-accepting chemotaxis protein K03406,K05874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 370.0
CMS2_k127_6876944_11 transport system permease K02026,K05815,K10238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 366.0
CMS2_k127_6876944_12 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 317.0
CMS2_k127_6876944_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 315.0
CMS2_k127_6876944_14 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 310.0
CMS2_k127_6876944_15 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00172,K18357 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006963 273.0
CMS2_k127_6876944_16 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005318 261.0
CMS2_k127_6876944_17 4Fe-4S binding domain K18358 - 1.2.1.58 0.00000000000000000000000000000000000000000001303 170.0
CMS2_k127_6876944_18 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000004721 122.0
CMS2_k127_6876944_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K18356 - 1.2.1.58 1.271e-211 664.0
CMS2_k127_6876944_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 6.974e-211 663.0
CMS2_k127_6876944_4 General secretory system II protein E domain protein K02454,K02652,K12276 - - 8.789e-205 665.0
CMS2_k127_6876944_5 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K18355 - 1.2.1.58,1.2.7.1 6.317e-194 621.0
CMS2_k127_6876944_6 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 591.0
CMS2_k127_6876944_7 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 523.0
CMS2_k127_6876944_8 Pyridine nucleotide-disulphide oxidoreductase K18359 - 1.2.1.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 460.0
CMS2_k127_6876944_9 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 445.0
CMS2_k127_6945163_0 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 310.0
CMS2_k127_6945163_1 - - - - 0.00000000000000000000000000001943 124.0
CMS2_k127_6945163_2 Protein of unknown function (DUF2933) - - - 0.000000000000000448 84.0
CMS2_k127_6945163_3 Heavy-metal-associated domain K07213 - - 0.00000000000006467 72.0
CMS2_k127_6945163_4 NfeD-like C-terminal, partner-binding K07403 - - 0.000001651 56.0
CMS2_k127_6945163_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000002909 51.0
CMS2_k127_6955712_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1056.0
CMS2_k127_6955712_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1041.0
CMS2_k127_6955712_10 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 349.0
CMS2_k127_6955712_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 329.0
CMS2_k127_6955712_12 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 288.0
CMS2_k127_6955712_13 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 297.0
CMS2_k127_6955712_14 RNA cap guanine-N2 methyltransferase K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 289.0
CMS2_k127_6955712_15 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001333 261.0
CMS2_k127_6955712_16 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000003276 268.0
CMS2_k127_6955712_17 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005093 257.0
CMS2_k127_6955712_18 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000000481 232.0
CMS2_k127_6955712_19 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000002774 181.0
CMS2_k127_6955712_2 Participates in both transcription termination and antitermination K02600 - - 2.447e-226 710.0
CMS2_k127_6955712_20 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000003513 163.0
CMS2_k127_6955712_21 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000001892 133.0
CMS2_k127_6955712_22 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000001811 138.0
CMS2_k127_6955712_23 - - - - 0.00000000002351 68.0
CMS2_k127_6955712_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 3.278e-212 667.0
CMS2_k127_6955712_4 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 543.0
CMS2_k127_6955712_5 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 512.0
CMS2_k127_6955712_6 twitching motility protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 459.0
CMS2_k127_6955712_7 D-amino acid dehydrogenase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 461.0
CMS2_k127_6955712_8 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 429.0
CMS2_k127_6955712_9 COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase Amino acid transport and metabolism Coenzyme metabolism K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 421.0
CMS2_k127_6986373_0 3-isopropylmalate dehydratase K01703 - 4.2.1.33,4.2.1.35 1.866e-240 759.0
CMS2_k127_6986373_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 612.0
CMS2_k127_6986373_2 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 337.0
CMS2_k127_6986373_3 chemotaxis K05874 - - 0.0000000000000000000000000000000000000000000000000000000000000002382 240.0
CMS2_k127_7010837_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.804e-285 882.0
CMS2_k127_7010837_1 Amino acid permease - - - 6.546e-272 851.0
CMS2_k127_7010837_10 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000003673 251.0
CMS2_k127_7010837_11 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000199 235.0
CMS2_k127_7010837_12 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000001946 192.0
CMS2_k127_7010837_13 protein conserved in bacteria K09966 - - 0.00000000000000000000000000000000000000000000000000004365 189.0
CMS2_k127_7010837_14 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000001198 189.0
CMS2_k127_7010837_15 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000001268 173.0
CMS2_k127_7010837_16 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000008079 165.0
CMS2_k127_7010837_17 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000001139 166.0
CMS2_k127_7010837_18 GYD domain - - - 0.00000000000000000000000000000000005807 136.0
CMS2_k127_7010837_19 TPR repeat - - - 0.00000000000000000000000000000001792 128.0
CMS2_k127_7010837_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.642e-269 849.0
CMS2_k127_7010837_20 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000001794 136.0
CMS2_k127_7010837_21 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000001121 124.0
CMS2_k127_7010837_22 - - - - 0.00000000000000000000000000004622 122.0
CMS2_k127_7010837_23 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000006079 100.0
CMS2_k127_7010837_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 8.045e-261 821.0
CMS2_k127_7010837_4 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 7.457e-260 806.0
CMS2_k127_7010837_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 568.0
CMS2_k127_7010837_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 442.0
CMS2_k127_7010837_7 Belongs to the LDH2 MDH2 oxidoreductase family K13609,K16844 - 1.1.1.338,1.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 381.0
CMS2_k127_7010837_8 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 363.0
CMS2_k127_7010837_9 Tyrosine recombinase xerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 363.0
CMS2_k127_783680_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1152.0
CMS2_k127_783680_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000219 250.0
CMS2_k127_783680_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000002326 218.0
CMS2_k127_783680_3 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000002915 182.0
CMS2_k127_783680_4 Thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000008712 161.0
CMS2_k127_783680_5 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000171 149.0
CMS2_k127_783680_6 Protein of unknown function (DUF2946) - - - 0.00000000000000000000000000000000000803 143.0
CMS2_k127_783680_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000004974 84.0
CMS2_k127_81683_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1046.0
CMS2_k127_81683_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.788e-223 696.0
CMS2_k127_884839_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1213.0
CMS2_k127_884839_1 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 576.0
CMS2_k127_884839_10 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000002828 132.0
CMS2_k127_884839_11 radical SAM - - - 0.000000000000000000000004265 102.0
CMS2_k127_884839_12 Modulates RecA activity K03565 - - 0.000000000000000000006656 105.0
CMS2_k127_884839_13 Cyclic nucleotide-monophosphate binding domain - - - 0.0003759 47.0
CMS2_k127_884839_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 549.0
CMS2_k127_884839_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 528.0
CMS2_k127_884839_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 447.0
CMS2_k127_884839_5 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 447.0
CMS2_k127_884839_6 PFAM ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 406.0
CMS2_k127_884839_7 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 388.0
CMS2_k127_884839_8 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000004471 184.0
CMS2_k127_884839_9 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000002036 146.0
CMS2_k127_89371_0 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 438.0
CMS2_k127_89371_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 345.0
CMS2_k127_89371_2 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000005114 172.0
CMS2_k127_89371_4 Protein of unknown function (DUF2846) - - - 0.000001483 60.0
CMS2_k127_903296_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 381.0
CMS2_k127_903296_1 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 308.0
CMS2_k127_903296_10 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000003526 136.0
CMS2_k127_903296_11 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.00000000000000000003825 90.0
CMS2_k127_903296_12 Domain of unknown function (DUF4936) - - - 0.0000000000008977 80.0
CMS2_k127_903296_2 Short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001847 277.0
CMS2_k127_903296_3 allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001097 269.0
CMS2_k127_903296_4 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001083 244.0
CMS2_k127_903296_5 dna polymerase iii K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000002733 241.0
CMS2_k127_903296_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000002327 214.0
CMS2_k127_903296_7 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000005065 216.0
CMS2_k127_903296_8 Allophanate hydrolase subunit 1 - - - 0.00000000000000000000000000000000000000000000000000000582 198.0
CMS2_k127_903296_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000006518 178.0
CMS2_k127_91610_0 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 453.0
CMS2_k127_91610_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 346.0
CMS2_k127_91610_2 Hydantoinase B/oxoprolinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 323.0
CMS2_k127_91610_3 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001317 279.0
CMS2_k127_91610_4 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001419 258.0
CMS2_k127_91610_5 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000004728 222.0
CMS2_k127_91610_6 - - - - 0.0000001519 55.0
CMS2_k127_934192_0 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 299.0
CMS2_k127_934192_1 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008783 276.0
CMS2_k127_934192_2 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000005563 139.0