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Overview

ID MAG00445
Name CMS2_bin.59
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Campylobacterota
Class Campylobacteria
Order Campylobacterales
Family Sulfurovaceae
Genus Sulfurovum
Species
Assembly information
Completeness (%) 85.71
Contamination (%) 3.13
GC content (%) 40.0
N50 (bp) 8,464
Genome size (bp) 1,792,829

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1844

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1029175_0 DNA polymerase K02337 - 2.7.7.7 0.0 1187.0
CMS2_k127_1030587_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1646.0
CMS2_k127_1030587_1 abc transporter atp-binding protein - - - 0.0 1054.0
CMS2_k127_1030587_2 AsmA-like C-terminal region - - - 1.115e-291 902.0
CMS2_k127_1030587_3 DNA recombination protein K09760 - - 1.978e-291 899.0
CMS2_k127_1030587_4 ABC-type transport system involved in lipoprotein release permease component K02004 - - 1.052e-242 752.0
CMS2_k127_1030587_5 Transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 458.0
CMS2_k127_1030587_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 310.0
CMS2_k127_1030587_7 polyphosphate kinase K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 293.0
CMS2_k127_1030587_8 Belongs to the UPF0061 (SELO) family - - - 0.000000000000000000000000000000000000000000000000000000000000005104 216.0
CMS2_k127_1030587_9 COG1393 Arsenate reductase and related K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000003772 209.0
CMS2_k127_1052092_0 hydrogenase (NiFe) small subunit HydA K05927 - 1.12.5.1 0.0 1520.0
CMS2_k127_1052092_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1351.0
CMS2_k127_1052092_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 3.479e-297 918.0
CMS2_k127_1052092_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 2.196e-228 710.0
CMS2_k127_1052092_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 4.208e-201 627.0
CMS2_k127_1052092_5 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 542.0
CMS2_k127_1052092_6 Membrane K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 332.0
CMS2_k127_1052092_7 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 291.0
CMS2_k127_1052092_8 Protein of unknown function (DUF2905) - - - 0.000000000000000000000000000002139 121.0
CMS2_k127_1069814_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1702.0
CMS2_k127_1069814_1 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 3.253e-264 815.0
CMS2_k127_1069814_10 Belongs to the peptidase M24B family K01262 - 3.4.11.9 1.353e-204 640.0
CMS2_k127_1069814_11 flagellar biosynthesis K02404 - - 3.084e-201 630.0
CMS2_k127_1069814_12 Domain of unknown function DUF21 - - - 2.808e-196 615.0
CMS2_k127_1069814_13 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 503.0
CMS2_k127_1069814_14 COG1538 Outer membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 472.0
CMS2_k127_1069814_15 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 452.0
CMS2_k127_1069814_16 cation efflux system protein K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 424.0
CMS2_k127_1069814_17 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 330.0
CMS2_k127_1069814_18 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 314.0
CMS2_k127_1069814_19 Bacterial protein of unknown function (DUF898) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 325.0
CMS2_k127_1069814_2 COG0513 Superfamily II DNA and RNA K11927 - 3.6.4.13 1.193e-259 803.0
CMS2_k127_1069814_20 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 322.0
CMS2_k127_1069814_21 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 299.0
CMS2_k127_1069814_22 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 292.0
CMS2_k127_1069814_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002486 275.0
CMS2_k127_1069814_24 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001034 260.0
CMS2_k127_1069814_26 - - - - 0.000000000000000000000000000000000000000000000000000000000002396 209.0
CMS2_k127_1069814_28 response regulator - - - 0.00000000000000000000000000000000000000000000000000000006231 202.0
CMS2_k127_1069814_29 Cytochrome c553 K08738 - - 0.00000000000000000000000000000000000000000000000001834 180.0
CMS2_k127_1069814_3 COG0845 membrane-fusion protein - - - 6.649e-257 794.0
CMS2_k127_1069814_30 - - - - 0.00000000000000000000000000000000000001541 143.0
CMS2_k127_1069814_32 Putative transmembrane protein (PGPGW) - - - 0.0000000000000000000000000000001841 127.0
CMS2_k127_1069814_34 toxin secretion ABC transporter ATP-binding protein K02021 - - 0.0000000000000000000000000004349 126.0
CMS2_k127_1069814_35 Cytochrome c - - - 0.0000000000000000000000000007558 116.0
CMS2_k127_1069814_36 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.000000000000003971 74.0
CMS2_k127_1069814_37 Domain of unknown function (DUF4395) - - - 0.000000000000009557 81.0
CMS2_k127_1069814_38 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000001358 59.0
CMS2_k127_1069814_4 Acts as a magnesium transporter K06213 - - 1.169e-256 795.0
CMS2_k127_1069814_5 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 1.153e-249 772.0
CMS2_k127_1069814_6 Outer membrane component of multidrug efflux pump - - - 1.097e-238 744.0
CMS2_k127_1069814_7 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 1.862e-233 724.0
CMS2_k127_1069814_8 Histidine kinase K02484 - 2.7.13.3 1.003e-232 722.0
CMS2_k127_1069814_9 Cysteine-rich secretory protein family - - - 5.827e-205 644.0
CMS2_k127_1093090_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1328.0
CMS2_k127_1093090_1 L,D-transpeptidase catalytic domain K21470 - - 0.0 1006.0
CMS2_k127_1093090_2 Protein conserved in bacteria - - - 1.184e-270 838.0
CMS2_k127_1093090_3 outer membrane porin, OprD family - - - 2.237e-194 610.0
CMS2_k127_1093090_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 488.0
CMS2_k127_1093090_5 Sel1 domain protein repeat-containing protein K07126 GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0019862,GO:0019865,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050865,GO:0050866,GO:0065007,GO:1902563,GO:1902564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 415.0
CMS2_k127_1093090_6 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 413.0
CMS2_k127_1093090_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000003056 228.0
CMS2_k127_1093090_9 Fe2 transport system protein A K04758 - - 0.00000000000000000000000000000000000001491 144.0
CMS2_k127_1099374_0 ABC transporter, ATP-binding protein K15738 - - 0.0 1212.0
CMS2_k127_1099374_1 threonine synthase K01733 - 4.2.3.1 6.758e-313 959.0
CMS2_k127_1099374_10 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 428.0
CMS2_k127_1099374_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 338.0
CMS2_k127_1099374_12 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 279.0
CMS2_k127_1099374_13 thioesterase K02614 - - 0.000000000000000000000000000000000000000000000000000000000000000000002041 236.0
CMS2_k127_1099374_14 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000002822 227.0
CMS2_k127_1099374_2 Endoribonuclease that initiates mRNA decay K18682 - - 1.138e-301 928.0
CMS2_k127_1099374_3 Peptidase M48 K06013 - 3.4.24.84 9.142e-251 777.0
CMS2_k127_1099374_4 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 598.0
CMS2_k127_1099374_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 549.0
CMS2_k127_1099374_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 526.0
CMS2_k127_1099374_7 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 511.0
CMS2_k127_1099374_8 hmm pf04305 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 503.0
CMS2_k127_1099374_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 439.0
CMS2_k127_1101062_0 Mur ligase middle domain K01929 - 6.3.2.10 2.657e-270 833.0
CMS2_k127_1101062_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 480.0
CMS2_k127_1101062_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 477.0
CMS2_k127_1101062_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000292 217.0
CMS2_k127_1101062_4 - - - - 0.000000000000000000000000000000000000000000000000000000000004679 210.0
CMS2_k127_1101062_5 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000001109 132.0
CMS2_k127_1144458_0 amino acid carrier protein K03310 - - 1.769e-286 883.0
CMS2_k127_1144458_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000035 223.0
CMS2_k127_1144458_2 - - - - 0.00000000000000000000000000000000001173 136.0
CMS2_k127_1144458_3 - - - - 0.00000004052 54.0
CMS2_k127_1152518_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 8.92e-318 976.0
CMS2_k127_1152518_1 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 3.127e-237 734.0
CMS2_k127_1152518_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 325.0
CMS2_k127_1152518_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 281.0
CMS2_k127_1152518_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000000000000000000000000000003855 191.0
CMS2_k127_1152518_5 Jag_N K06346 - - 0.00000000000000000000002393 100.0
CMS2_k127_1152518_6 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000001449 82.0
CMS2_k127_1191048_0 DNA helicase K03657 - 3.6.4.12 0.0 1328.0
CMS2_k127_1191048_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 580.0
CMS2_k127_1191048_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 579.0
CMS2_k127_1191048_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 527.0
CMS2_k127_1191048_4 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 482.0
CMS2_k127_1191048_5 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 340.0
CMS2_k127_1191048_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003255 266.0
CMS2_k127_1200641_0 COG2223 Nitrate nitrite transporter K02575 - - 6.068e-254 787.0
CMS2_k127_1200641_1 ABC transporter permease K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 415.0
CMS2_k127_1200641_2 ABC transporter K15555,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 407.0
CMS2_k127_1200641_3 COG0607 Rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
CMS2_k127_1200641_5 Domain of unknown function DUF302 K12308 - 3.2.1.23 0.0000000005318 65.0
CMS2_k127_1202858_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 507.0
CMS2_k127_1202858_1 PFAM CHAD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 497.0
CMS2_k127_1202858_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 426.0
CMS2_k127_1202858_3 response to heat K03668 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000754 244.0
CMS2_k127_1229531_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.459e-312 960.0
CMS2_k127_1229531_1 apolipoprotein N-acyltransferase K03820 - - 3.819e-203 638.0
CMS2_k127_1229531_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 594.0
CMS2_k127_1229531_3 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 342.0
CMS2_k127_1229531_4 - - - - 0.00000000000000000000000000000000000000000000000000000000001223 209.0
CMS2_k127_1229531_5 Preprotein translocase K03210 - - 0.000000000000000000000000000000000000000003561 157.0
CMS2_k127_1233035_0 na -driven multidrug efflux - - - 4.236e-255 790.0
CMS2_k127_1233035_1 Enoyl-(Acyl carrier protein) reductase K16216 - 1.1.1.320 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 435.0
CMS2_k127_1233035_2 YHS domain K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 296.0
CMS2_k127_1233035_3 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002142 289.0
CMS2_k127_1233035_7 Cytochrome c - - - 0.000000000000000009972 85.0
CMS2_k127_1258329_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 5.576e-309 955.0
CMS2_k127_1258329_1 COG2067 Long-chain fatty acid transport protein K06076 - - 8.216e-208 651.0
CMS2_k127_1258329_2 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 556.0
CMS2_k127_1258329_3 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 536.0
CMS2_k127_1258329_5 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 332.0
CMS2_k127_1270842_0 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 343.0
CMS2_k127_1270842_1 - K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002109 270.0
CMS2_k127_1270842_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000003764 150.0
CMS2_k127_1276841_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 4.525e-258 796.0
CMS2_k127_1276841_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 404.0
CMS2_k127_1276841_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 351.0
CMS2_k127_1276841_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 303.0
CMS2_k127_1276841_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000251 260.0
CMS2_k127_1276841_5 Belongs to the UPF0246 family K09861 - - 0.0000000000000000000000000000000000000000000000000000000000004765 212.0
CMS2_k127_1276841_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000007557 204.0
CMS2_k127_1276841_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000000003019 198.0
CMS2_k127_1276841_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000000002768 114.0
CMS2_k127_1276841_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000002233 101.0
CMS2_k127_1278301_0 sulfur dehydrogenase subunit K17225 - - 3.685e-233 727.0
CMS2_k127_1278301_1 Cytochrome c K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 328.0
CMS2_k127_1278301_2 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 303.0
CMS2_k127_1278301_3 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006413 245.0
CMS2_k127_1278301_4 - K17226 - - 0.000000000000000000000000000000000000000000003117 168.0
CMS2_k127_1278301_5 PFAM MOSC domain - - - 0.000000000000000000000000000000000000000006767 159.0
CMS2_k127_1278301_6 Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000426 116.0
CMS2_k127_1278301_8 Thioredoxin-like domain - - - 0.00000000000000000000000316 108.0
CMS2_k127_1278301_9 Domain of unknown function DUF302 - - - 0.000000000000287 75.0
CMS2_k127_1287161_0 ABC-type multidrug transport system ATPase and permease K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 549.0
CMS2_k127_1287161_1 Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 480.0
CMS2_k127_1287161_2 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 409.0
CMS2_k127_1294533_0 Putative diguanylate phosphodiesterase - - - 0.0 1152.0
CMS2_k127_1294533_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0 999.0
CMS2_k127_1294533_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 356.0
CMS2_k127_1294533_4 COG0760 Parvulin-like peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000005669 184.0
CMS2_k127_1295586_0 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 515.0
CMS2_k127_1295586_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000006777 218.0
CMS2_k127_1295586_4 - - - - 0.00000000000000000000000000000000000004037 145.0
CMS2_k127_1295586_6 membrane protein (DUF2078) K08982 - - 0.000000000000000001644 86.0
CMS2_k127_1310894_0 arginine decarboxylase K01585 - 4.1.1.19 3.214e-252 783.0
CMS2_k127_1310894_1 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 346.0
CMS2_k127_131573_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1214.0
CMS2_k127_131573_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.01e-321 987.0
CMS2_k127_131573_2 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 517.0
CMS2_k127_131573_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 428.0
CMS2_k127_131573_4 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 369.0
CMS2_k127_131573_5 HPP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 325.0
CMS2_k127_131573_6 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009599 282.0
CMS2_k127_131573_7 Belongs to the globin family K05916 - 1.14.12.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003299 274.0
CMS2_k127_1340533_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 8.626e-271 833.0
CMS2_k127_1340533_1 molybdopterin biosynthesis K03750 - 2.10.1.1 7.633e-249 769.0
CMS2_k127_1340533_10 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 331.0
CMS2_k127_1340533_12 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000001416 216.0
CMS2_k127_1340533_13 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000000000000000000000000000000000000000000019 168.0
CMS2_k127_1340533_14 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000000003306 139.0
CMS2_k127_1340533_15 Protein conserved in bacteria - - - 0.0000000009285 67.0
CMS2_k127_1340533_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 1.752e-208 649.0
CMS2_k127_1340533_3 ubiquinol cytochrome c oxidoreductase, cytochrome c1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 578.0
CMS2_k127_1340533_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 507.0
CMS2_k127_1340533_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 493.0
CMS2_k127_1340533_6 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 478.0
CMS2_k127_1340533_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 428.0
CMS2_k127_1340533_8 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 391.0
CMS2_k127_1340533_9 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 363.0
CMS2_k127_1347368_0 Belongs to the UPF0753 family K09822 - - 0.0 1699.0
CMS2_k127_1347368_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit - - - 3e-323 992.0
CMS2_k127_1347368_10 YcxB-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008585 274.0
CMS2_k127_1347368_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001131 228.0
CMS2_k127_1347368_12 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K02573,K13795,K18930 - 1.2.7.1 0.00000000000000000000000000000000000000000000003435 169.0
CMS2_k127_1347368_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 9.626e-257 792.0
CMS2_k127_1347368_3 Cobalamin synthesis protein - - - 1.189e-195 613.0
CMS2_k127_1347368_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 572.0
CMS2_k127_1347368_5 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 457.0
CMS2_k127_1347368_6 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 403.0
CMS2_k127_1347368_7 phosphate ion binding K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 382.0
CMS2_k127_1347368_8 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 359.0
CMS2_k127_1347368_9 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 327.0
CMS2_k127_1356944_0 Domain of unknown function (DUF3482) - - - 5.031e-273 843.0
CMS2_k127_1356944_1 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 7.247e-263 811.0
CMS2_k127_1356944_2 4Fe-4S binding domain - - - 9.203e-212 659.0
CMS2_k127_1356944_3 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 517.0
CMS2_k127_1356944_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 321.0
CMS2_k127_1356944_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000004803 124.0
CMS2_k127_1402260_0 von Willebrand factor, type A K07114 - - 2.669e-270 837.0
CMS2_k127_1402260_1 Protein conserved in bacteria - - - 4.394e-194 610.0
CMS2_k127_1402260_2 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 455.0
CMS2_k127_1402260_3 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00001041 48.0
CMS2_k127_1402260_4 Oxygen tolerance - - - 0.00004179 55.0
CMS2_k127_1564990_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.682e-318 974.0
CMS2_k127_1564990_1 auxin efflux carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000457 254.0
CMS2_k127_1593815_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0 1032.0
CMS2_k127_1593815_1 COG1055 Na H antiporter NhaD and related arsenite - - - 5.41e-275 847.0
CMS2_k127_1612801_0 phosphorylase kinase alphabeta K07190 - - 0.0 1419.0
CMS2_k127_1631814_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1377.0
CMS2_k127_1631814_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 1.99e-245 759.0
CMS2_k127_1631814_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 3.046e-243 752.0
CMS2_k127_1631814_3 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 441.0
CMS2_k127_1631814_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000000265 132.0
CMS2_k127_1679679_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 9.803e-220 682.0
CMS2_k127_1679679_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 577.0
CMS2_k127_1679679_2 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 497.0
CMS2_k127_1679679_3 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 495.0
CMS2_k127_1679679_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 466.0
CMS2_k127_1679679_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 301.0
CMS2_k127_1679679_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 300.0
CMS2_k127_1679679_7 Belongs to the ATPase B chain family K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001034 243.0
CMS2_k127_1679679_8 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000008062 213.0
CMS2_k127_1684302_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 512.0
CMS2_k127_1684302_1 involved in molybdopterin and thiamine biosynthesis family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 406.0
CMS2_k127_1684302_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 336.0
CMS2_k127_1684302_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 294.0
CMS2_k127_1712221_0 L,D-transpeptidase catalytic domain - - - 5.468e-240 744.0
CMS2_k127_1712221_1 HI0933 family K07007 - - 3.157e-231 717.0
CMS2_k127_1712221_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006908 227.0
CMS2_k127_1712221_3 Sulfatase - - - 0.0000000000408 63.0
CMS2_k127_1743323_0 Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) K00557 - 2.1.1.35 1.728e-225 700.0
CMS2_k127_1743323_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 3.745e-220 685.0
CMS2_k127_1743323_2 glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 385.0
CMS2_k127_1747763_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.0 1367.0
CMS2_k127_1747763_1 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000003625 238.0
CMS2_k127_1747763_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000001198 195.0
CMS2_k127_1768359_0 Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 462.0
CMS2_k127_1768359_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 360.0
CMS2_k127_1768359_2 oxygen carrier activity K07216 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003484 269.0
CMS2_k127_1768359_3 oxygen carrier activity K07216 - - 0.00000000000000000000000000000000000000000000000000000000000000003595 224.0
CMS2_k127_1768359_5 oxygen carrier activity K07216 - - 0.00000000000000000000000000000000002762 139.0
CMS2_k127_182913_0 Predicted membrane protein (DUF2207) - - - 0.0 1050.0
CMS2_k127_182913_1 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 384.0
CMS2_k127_182913_2 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009658 377.0
CMS2_k127_182913_4 - - - - 0.00000000000000000000000000000000000000000000374 166.0
CMS2_k127_182913_5 LemA family K03744 - - 0.000000001639 58.0
CMS2_k127_1850942_0 phosphate-selective porin O and P - - - 6.487e-254 785.0
CMS2_k127_1850942_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 1.216e-245 763.0
CMS2_k127_1850942_2 COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 493.0
CMS2_k127_1850942_3 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 434.0
CMS2_k127_1850942_5 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000002759 112.0
CMS2_k127_1939718_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1158.0
CMS2_k127_1939718_1 May be involved in recombinational repair of damaged DNA K03631 - - 2.377e-282 872.0
CMS2_k127_1939718_2 lytic murein transglycosylase K08307 - - 9.729e-198 620.0
CMS2_k127_1939718_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 542.0
CMS2_k127_1939718_4 hydrolase, TatD K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 468.0
CMS2_k127_1939718_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 368.0
CMS2_k127_1939718_6 Histidine kinase K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001458 271.0
CMS2_k127_1939718_7 Histidine kinase K02030 - - 0.00000007674 53.0
CMS2_k127_199666_0 Surface antigen - - - 1.403e-270 834.0
CMS2_k127_199666_1 Heat shock 70 kDa protein K04043 - - 1.117e-254 787.0
CMS2_k127_2033525_0 integral membrane protein - - - 8.03e-203 634.0
CMS2_k127_2033525_1 Anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 383.0
CMS2_k127_2033525_2 phosphoribosyltransferase K00769 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 284.0
CMS2_k127_2033525_3 Belongs to the succinate malate CoA ligase beta subunit family K15231 - 2.3.3.8 0.000000000000005458 74.0
CMS2_k127_2045046_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1956.0
CMS2_k127_2045046_1 MgtC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 599.0
CMS2_k127_2045046_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 450.0
CMS2_k127_2045046_3 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0000000000000000004591 89.0
CMS2_k127_2045046_4 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.00000000000391 67.0
CMS2_k127_2058398_0 GGDEF domain - - - 2.515e-255 795.0
CMS2_k127_2058398_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 568.0
CMS2_k127_2058398_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 509.0
CMS2_k127_2058398_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000000000001045 153.0
CMS2_k127_2065223_0 Sulfatase-modifying factor enzyme 1 - - - 0.0 1002.0
CMS2_k127_2065223_1 COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 1.166e-314 970.0
CMS2_k127_2065223_2 Aminotransferase, class I K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 436.0
CMS2_k127_2065223_3 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 0.00000000000000000000000000000000003034 134.0
CMS2_k127_2081277_0 peptidase U32 family K08303 - - 1.175e-290 893.0
CMS2_k127_2081277_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.389e-272 841.0
CMS2_k127_2081277_10 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 372.0
CMS2_k127_2081277_11 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 321.0
CMS2_k127_2081277_12 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 304.0
CMS2_k127_2081277_13 AIR carboxylase K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000003444 235.0
CMS2_k127_2081277_14 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000000003486 153.0
CMS2_k127_2081277_15 RNA-binding protein K06960 - - 0.0000000000000000000000000000000000000001092 151.0
CMS2_k127_2081277_16 Belongs to the UPF0235 family K09131 - - 0.00000000004185 66.0
CMS2_k127_2081277_2 glutamine synthetase K01915 - 6.3.1.2 1.277e-270 836.0
CMS2_k127_2081277_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 2.999e-230 715.0
CMS2_k127_2081277_4 3-deoxy-d-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 3.692e-226 704.0
CMS2_k127_2081277_5 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 7.35e-198 616.0
CMS2_k127_2081277_6 PHP domain K04486 - 3.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 520.0
CMS2_k127_2081277_7 Belongs to the pseudouridine synthase RluA family K06179,K06180 - 5.4.99.23,5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 475.0
CMS2_k127_2081277_8 dinuclear metal center protein, YbgI K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 462.0
CMS2_k127_2081277_9 COG1579 Zn-ribbon protein possibly nucleic acid-binding K07164,K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 419.0
CMS2_k127_20898_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004722 266.0
CMS2_k127_20898_2 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000003519 136.0
CMS2_k127_2111454_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.833e-272 839.0
CMS2_k127_2111454_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 8.447e-214 666.0
CMS2_k127_2111454_2 Sodium hydrogen exchanger - - - 3.693e-210 657.0
CMS2_k127_2111454_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 419.0
CMS2_k127_2111454_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 348.0
CMS2_k127_2111454_6 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000002721 158.0
CMS2_k127_2111454_7 - - - - 0.000000000000000000000000000000000000001001 148.0
CMS2_k127_2112265_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1888.0
CMS2_k127_2112265_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 5.242e-311 955.0
CMS2_k127_2112265_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000005217 188.0
CMS2_k127_2112265_13 Acetyltransferase (GNAT) domain - - - 0.0000000006788 70.0
CMS2_k127_2112265_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 6.544e-269 830.0
CMS2_k127_2112265_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006845 591.0
CMS2_k127_2112265_4 Sel1-like repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 582.0
CMS2_k127_2112265_5 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 532.0
CMS2_k127_2112265_6 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 518.0
CMS2_k127_2112265_7 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 387.0
CMS2_k127_2112265_8 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 318.0
CMS2_k127_2112265_9 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000005665 236.0
CMS2_k127_2120593_0 Nitrogenase protein alpha chain K02586 - 1.18.6.1 8.09e-299 919.0
CMS2_k127_2120593_1 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 5.326e-284 875.0
CMS2_k127_2120593_10 - - - - 0.0000000000000000000000000000000000003276 141.0
CMS2_k127_2120593_11 Rop-like - - - 0.00000000000000000000003002 100.0
CMS2_k127_2120593_12 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000003205 51.0
CMS2_k127_2120593_13 Acetyltransferase (GNAT) domain - - - 0.0002323 52.0
CMS2_k127_2120593_2 Nitrogenase cofactor biosynthesis protein NifB K02585 - - 4.155e-271 838.0
CMS2_k127_2120593_3 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 545.0
CMS2_k127_2120593_4 COG4886 Leucine-rich repeat (LRR) protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 555.0
CMS2_k127_2120593_5 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 529.0
CMS2_k127_2120593_6 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 442.0
CMS2_k127_2120593_7 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000007372 182.0
CMS2_k127_2120593_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000005546 167.0
CMS2_k127_2120593_9 - - - - 0.0000000000000000000000000000000000001725 144.0
CMS2_k127_2137014_0 Belongs to the DEAD box helicase family K05592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 2.501e-294 906.0
CMS2_k127_2137014_1 PFAM SufBD protein K07033 - - 1.548e-209 655.0
CMS2_k127_2137014_10 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09015 - - 0.0000000000002109 69.0
CMS2_k127_2137014_3 COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 427.0
CMS2_k127_2137014_4 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 318.0
CMS2_k127_2137014_5 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001217 281.0
CMS2_k127_2137014_6 COG2166 SufE protein probably involved in Fe-S center assembly K02426 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005104 276.0
CMS2_k127_2137014_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003729 250.0
CMS2_k127_2137014_8 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009992 246.0
CMS2_k127_2147128_0 OmpA family K02557 - - 1.711e-219 685.0
CMS2_k127_2147128_1 Peptidase M30 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 505.0
CMS2_k127_2147128_3 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001514 260.0
CMS2_k127_2159989_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 4.535e-262 808.0
CMS2_k127_2159989_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 1.092e-224 700.0
CMS2_k127_2159989_2 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 360.0
CMS2_k127_2159989_3 - - - - 0.000000000004849 70.0
CMS2_k127_2179563_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.069e-285 879.0
CMS2_k127_2179563_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.184e-281 865.0
CMS2_k127_2179563_2 mechanosensitive ion channel K16052 - - 5.825e-232 721.0
CMS2_k127_2179563_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 4.567e-201 627.0
CMS2_k127_2179563_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0003674,GO:0005488,GO:0005515,GO:0042802 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 488.0
CMS2_k127_2179563_5 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004253 274.0
CMS2_k127_2179563_7 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000115 182.0
CMS2_k127_2182216_0 COG0155 Sulfite reductase, beta subunit (hemoprotein) K00366,K00392 - 1.7.7.1,1.8.7.1 0.0 1167.0
CMS2_k127_2182216_1 COG0631 Serine threonine protein phosphatase K12132 - 2.7.11.1 0.0 1024.0
CMS2_k127_2182216_2 4Fe-4S dicluster domain K07307 - - 1.283e-302 932.0
CMS2_k127_2182216_3 COG2223 Nitrate nitrite transporter K02575 - - 1.221e-259 802.0
CMS2_k127_2182216_4 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 3.889e-256 792.0
CMS2_k127_2182216_5 Molybdopterin oxidoreductase Fe4S4 domain K00372 - - 1.837e-242 752.0
CMS2_k127_2187876_0 permease K11720 - - 7.163e-206 643.0
CMS2_k127_2187876_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 353.0
CMS2_k127_2187876_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 344.0
CMS2_k127_2187876_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 330.0
CMS2_k127_2200523_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1589.0
CMS2_k127_2200523_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0 1335.0
CMS2_k127_2200523_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 511.0
CMS2_k127_2200523_11 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 466.0
CMS2_k127_2200523_12 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 434.0
CMS2_k127_2200523_13 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 407.0
CMS2_k127_2200523_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 361.0
CMS2_k127_2200523_15 phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 344.0
CMS2_k127_2200523_16 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 308.0
CMS2_k127_2200523_17 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000000001656 192.0
CMS2_k127_2200523_18 - - - - 0.000000000000000000000000000000000000000000000000000005863 190.0
CMS2_k127_2200523_19 - - - - 0.000000000000000000000000000000000000000000006152 164.0
CMS2_k127_2200523_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 4.205e-282 868.0
CMS2_k127_2200523_3 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 2.957e-233 724.0
CMS2_k127_2200523_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 1.125e-225 700.0
CMS2_k127_2200523_5 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 1.533e-220 684.0
CMS2_k127_2200523_6 Sodium/calcium exchanger protein K07300 - - 1.563e-206 645.0
CMS2_k127_2200523_7 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 1.975e-195 611.0
CMS2_k127_2200523_8 Pseudouridine synthase K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 588.0
CMS2_k127_2200523_9 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 526.0
CMS2_k127_2209574_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1101.0
CMS2_k127_2209574_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 432.0
CMS2_k127_2209574_2 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 431.0
CMS2_k127_2209574_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 330.0
CMS2_k127_2209574_4 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 296.0
CMS2_k127_223020_0 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1611.0
CMS2_k127_223020_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.452e-272 839.0
CMS2_k127_223020_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 5.657e-213 662.0
CMS2_k127_223020_3 pyridine nucleotide-disulfide oxidoreductase K00384 - 1.8.1.9 5.978e-198 621.0
CMS2_k127_223020_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 411.0
CMS2_k127_223020_5 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 362.0
CMS2_k127_223020_6 putative NADH-ubiquinone oxidoreductase chain E K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000001111 186.0
CMS2_k127_223020_7 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000008756 119.0
CMS2_k127_223020_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.000000000001424 67.0
CMS2_k127_2251762_0 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member - - - 1.03e-302 937.0
CMS2_k127_2251762_1 PFAM Helicase conserved C-terminal domain K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 375.0
CMS2_k127_2251762_2 Domain of unknown function (DUF4918) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 352.0
CMS2_k127_2251762_3 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000003475 116.0
CMS2_k127_2277581_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 8.524e-220 682.0
CMS2_k127_2277581_1 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 529.0
CMS2_k127_2277581_2 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 490.0
CMS2_k127_230914_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1074.0
CMS2_k127_230914_1 L,D-transpeptidase catalytic domain K21470 - - 0.0 1021.0
CMS2_k127_230914_10 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 514.0
CMS2_k127_230914_11 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 482.0
CMS2_k127_230914_12 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 375.0
CMS2_k127_230914_13 COG3637 Opacity protein and related surface antigens - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 343.0
CMS2_k127_230914_14 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 337.0
CMS2_k127_230914_15 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 300.0
CMS2_k127_230914_16 GTP-binding protein K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009914 281.0
CMS2_k127_230914_17 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000001269 218.0
CMS2_k127_230914_18 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000008864 214.0
CMS2_k127_230914_19 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000003352 66.0
CMS2_k127_230914_2 Single-stranded-DNA-specific exonuclease (RecJ) K07462 - - 5.667e-303 932.0
CMS2_k127_230914_20 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000211 61.0
CMS2_k127_230914_3 Cysteine desulfurase K04487 - 2.8.1.7 1.325e-253 784.0
CMS2_k127_230914_4 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 7.465e-229 709.0
CMS2_k127_230914_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 1.093e-214 668.0
CMS2_k127_230914_6 Domain of unknown function DUF302 - - - 1.173e-210 655.0
CMS2_k127_230914_7 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 1.211e-202 632.0
CMS2_k127_230914_8 a g-specific adenine glycosylase K03575 - - 4.32e-196 613.0
CMS2_k127_230914_9 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.304e-195 617.0
CMS2_k127_2316197_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 413.0
CMS2_k127_2316197_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 360.0
CMS2_k127_2316197_2 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 330.0
CMS2_k127_233469_0 COG0025 NhaP-type Na H and K H K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 430.0
CMS2_k127_233469_1 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002724 241.0
CMS2_k127_23348_0 ABC transporter K02004 - - 1.048e-235 732.0
CMS2_k127_23348_1 Desulfoferrodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007101 266.0
CMS2_k127_23348_2 - - - - 0.000000000000000000000000000000000000000000000000000000005057 199.0
CMS2_k127_23348_3 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000000000000001857 149.0
CMS2_k127_2337116_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 2.29e-228 708.0
CMS2_k127_2337116_1 Archaea bacterial proteins of unknown function K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 433.0
CMS2_k127_2337116_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 362.0
CMS2_k127_2337116_3 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000002668 184.0
CMS2_k127_2337116_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000008528 144.0
CMS2_k127_2337116_5 - - - - 0.000000000000000000000000000000005174 129.0
CMS2_k127_2350560_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0 1101.0
CMS2_k127_2350560_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 3.864e-207 645.0
CMS2_k127_2350560_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 591.0
CMS2_k127_2350560_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 350.0
CMS2_k127_2350560_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000000000000131 127.0
CMS2_k127_235838_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 584.0
CMS2_k127_235838_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 524.0
CMS2_k127_2384469_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.174e-255 793.0
CMS2_k127_2384469_1 His Kinase A (phosphoacceptor) domain - - - 1.494e-249 787.0
CMS2_k127_2384469_10 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000128 164.0
CMS2_k127_2384469_11 phosphorelay signal transduction system - - - 0.0000000000000000000000000000001113 129.0
CMS2_k127_2384469_12 Protein of unknown function DUF89 K09116 - - 0.0000002077 52.0
CMS2_k127_2384469_13 Histidine kinase A domain protein K10715 - 2.7.13.3 0.00005907 49.0
CMS2_k127_2384469_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 599.0
CMS2_k127_2384469_3 Two-component sensor histidine kinase response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 417.0
CMS2_k127_2384469_4 Diguanylate cyclase K20959 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032879,GO:0040012,GO:0040013,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 380.0
CMS2_k127_2384469_5 signal transduction response regulator (GGDEF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 356.0
CMS2_k127_2384469_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 336.0
CMS2_k127_2384469_7 PAS domain K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002974 277.0
CMS2_k127_2384469_8 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000000000000000000000000000000000004699 232.0
CMS2_k127_2388273_0 glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 534.0
CMS2_k127_2388273_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 305.0
CMS2_k127_2400325_0 MltA-interacting protein MipA K07274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 472.0
CMS2_k127_2400325_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 427.0
CMS2_k127_2400325_2 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009463 248.0
CMS2_k127_2400325_3 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000002031 184.0
CMS2_k127_2400325_4 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000001923 169.0
CMS2_k127_2435782_0 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 597.0
CMS2_k127_2435782_1 4Fe-4S ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 494.0
CMS2_k127_2435782_2 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004664 264.0
CMS2_k127_2435782_3 Polysulphide reductase, NrfD - - - 0.0000000000001056 72.0
CMS2_k127_2481622_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 462.0
CMS2_k127_2481622_1 Protein of unknown function (DUF1566) K07126 - - 0.000000000000000004884 90.0
CMS2_k127_250898_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 400.0
CMS2_k127_250898_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 363.0
CMS2_k127_250898_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 302.0
CMS2_k127_250898_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 299.0
CMS2_k127_250898_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000000000001949 207.0
CMS2_k127_2518998_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 9.574e-223 693.0
CMS2_k127_2518998_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 559.0
CMS2_k127_2518998_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 423.0
CMS2_k127_2518998_3 Cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003443 253.0
CMS2_k127_2561355_0 hydrolase K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 532.0
CMS2_k127_2561355_1 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 427.0
CMS2_k127_2561355_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 389.0
CMS2_k127_2561355_3 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000002371 259.0
CMS2_k127_2561355_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001357 224.0
CMS2_k127_2561355_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000000000000006163 122.0
CMS2_k127_2591230_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.3,1.4.1.4 7.21e-286 879.0
CMS2_k127_2591230_1 Mg chelatase-related protein K07391 - - 1.114e-262 819.0
CMS2_k127_2591230_2 Major facilitator superfamily K05820 - - 2.313e-226 703.0
CMS2_k127_2591230_3 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 592.0
CMS2_k127_2591230_4 Belongs to the UPF0324 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 585.0
CMS2_k127_2591230_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 323.0
CMS2_k127_2591230_6 RDD family - - - 0.0000000000000000000000000002768 114.0
CMS2_k127_2609268_0 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.0 1035.0
CMS2_k127_2609268_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 594.0
CMS2_k127_2609268_2 META domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 319.0
CMS2_k127_2609268_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 302.0
CMS2_k127_2609268_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000006853 243.0
CMS2_k127_2609268_5 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000003142 176.0
CMS2_k127_2621820_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2558.0
CMS2_k127_2621820_1 Mechanosensitive ion channel - - - 3.743e-263 817.0
CMS2_k127_2621820_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 621.0
CMS2_k127_2621820_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 549.0
CMS2_k127_2621820_4 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 419.0
CMS2_k127_2621820_6 RecO N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 336.0
CMS2_k127_2621820_7 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 331.0
CMS2_k127_2635566_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0 1330.0
CMS2_k127_2635566_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1211.0
CMS2_k127_2635566_10 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000002381 84.0
CMS2_k127_2635566_11 Cupin 2, conserved barrel domain protein K11312 - - 0.000000000000005557 78.0
CMS2_k127_2635566_12 Transposase IS200 like - - - 0.000000000000649 68.0
CMS2_k127_2635566_2 COGs COG1252 NADH dehydrogenase FAD-containing subunit K17218 - 1.8.5.4 0.0 994.0
CMS2_k127_2635566_3 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 2.582e-320 983.0
CMS2_k127_2635566_4 Binding-protein-dependent transport system inner membrane component K02034 - - 7.674e-260 804.0
CMS2_k127_2635566_5 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 506.0
CMS2_k127_2635566_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 437.0
CMS2_k127_2635566_7 riboflavin synthase alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 388.0
CMS2_k127_2635566_8 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 - 4.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 330.0
CMS2_k127_269570_0 Cysteine desulfurase K04487 - 2.8.1.7 2.191e-217 678.0
CMS2_k127_269570_1 Highly conserved protein containing a thioredoxin domain K06888 - - 5.736e-217 691.0
CMS2_k127_269570_10 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000000001286 216.0
CMS2_k127_269570_11 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000007594 200.0
CMS2_k127_269570_12 - - - - 0.000000000000000000000000000000000000000000000001204 179.0
CMS2_k127_269570_13 Dinitrogenase iron-molybdenum cofactor biosynthesis protein K02596 - - 0.00000000000000000000000000000000000001509 147.0
CMS2_k127_269570_14 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000002353 135.0
CMS2_k127_269570_17 molybdate ion transport K02017,K06857 - 3.6.3.29,3.6.3.55 0.00000000000000004215 87.0
CMS2_k127_269570_18 Putative heavy-metal chelation K09138 - - 0.0000004443 56.0
CMS2_k127_269570_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.521e-214 670.0
CMS2_k127_269570_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000002166 243.0
CMS2_k127_269570_4 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000216 245.0
CMS2_k127_269570_5 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008097 244.0
CMS2_k127_269570_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000787 233.0
CMS2_k127_269570_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000002429 222.0
CMS2_k127_269570_8 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000003572 213.0
CMS2_k127_269570_9 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000002347 210.0
CMS2_k127_2750187_0 Histidine kinase K02030 - - 7.307e-238 763.0
CMS2_k127_2750187_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.738e-206 643.0
CMS2_k127_2750187_2 ABC transporter permease K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 397.0
CMS2_k127_2750187_3 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 393.0
CMS2_k127_2750187_4 Belongs to the ABC transporter superfamily K02010,K02052,K11072 - 3.6.3.30,3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 381.0
CMS2_k127_2750187_5 Zn-ribbon-containing protein involved in phosphonate metabolism K06193 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 350.0
CMS2_k127_3049750_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1247.0
CMS2_k127_3049750_1 chaperone-mediated protein folding - - - 1.871e-246 763.0
CMS2_k127_3049750_10 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000473 94.0
CMS2_k127_3049750_2 COGs COG0665 Glycine D-amino acid oxidase (deaminating) K15461 - 2.1.1.61 4.565e-221 688.0
CMS2_k127_3049750_3 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 519.0
CMS2_k127_3049750_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 429.0
CMS2_k127_3049750_5 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 399.0
CMS2_k127_3049750_6 PFAM HPP family protein K07168 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002094 260.0
CMS2_k127_3049750_7 GatB Yqey family protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000147 247.0
CMS2_k127_3049750_8 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000001557 176.0
CMS2_k127_3077494_0 7 transmembrane helices usually fused to an inactive transglutaminase - - - 1.167e-293 905.0
CMS2_k127_3077494_1 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 574.0
CMS2_k127_3077494_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 535.0
CMS2_k127_3077494_3 Putative ATP-dependant zinc protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 324.0
CMS2_k127_3077494_4 RNA pseudouridylate synthase K06175 - 5.4.99.26 0.0000000000000000000000000000000000000000000000000000000000000001872 221.0
CMS2_k127_3077494_5 DNA-binding protein VF530 - - - 0.00000000000000000000000000000000000000002091 153.0
CMS2_k127_3113906_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.472e-215 670.0
CMS2_k127_3113906_1 Membrane protease subunits - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 495.0
CMS2_k127_3113906_2 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 284.0
CMS2_k127_3113906_3 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000000000000006178 207.0
CMS2_k127_3122781_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0 1450.0
CMS2_k127_3122781_1 ribosomal protein S1 K02945 - - 0.0 1040.0
CMS2_k127_3122781_10 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 377.0
CMS2_k127_3122781_11 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 370.0
CMS2_k127_3122781_12 Hit family K02503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003377 238.0
CMS2_k127_3122781_13 5'-3' exoribonuclease activity K07082,K10565 - - 0.00000000000000007427 81.0
CMS2_k127_3122781_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0 1032.0
CMS2_k127_3122781_3 COG0841 Cation multidrug efflux pump - - - 0.0 1014.0
CMS2_k127_3122781_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 7.614e-309 951.0
CMS2_k127_3122781_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 2.362e-263 812.0
CMS2_k127_3122781_6 outer membrane efflux protein - - - 1.579e-249 774.0
CMS2_k127_3122781_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 8.614e-213 661.0
CMS2_k127_3122781_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 552.0
CMS2_k127_3122781_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 481.0
CMS2_k127_3132997_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1529.0
CMS2_k127_3132997_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 527.0
CMS2_k127_3132997_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 493.0
CMS2_k127_3215027_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 598.0
CMS2_k127_3215027_1 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000002853 197.0
CMS2_k127_3215027_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000006958 71.0
CMS2_k127_3240394_0 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 3.484e-273 843.0
CMS2_k127_3240394_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 2.62e-242 752.0
CMS2_k127_3240394_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 595.0
CMS2_k127_3240394_3 Potassium channel protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 445.0
CMS2_k127_3240394_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 428.0
CMS2_k127_3240394_5 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 400.0
CMS2_k127_3240394_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 325.0
CMS2_k127_3240394_7 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000000000000000000002363 138.0
CMS2_k127_3240394_8 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000834 130.0
CMS2_k127_3242563_0 Peptidase family M41 - - - 0.0 1700.0
CMS2_k127_3242563_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 1.33e-252 780.0
CMS2_k127_3242563_10 COG4886 Leucine-rich repeat (LRR) protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 370.0
CMS2_k127_3242563_12 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 348.0
CMS2_k127_3242563_14 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 293.0
CMS2_k127_3242563_15 COG2346, Truncated hemoglobins K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 279.0
CMS2_k127_3242563_16 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002546 260.0
CMS2_k127_3242563_17 oxygen carrier activity K07216 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002887 256.0
CMS2_k127_3242563_18 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003195 237.0
CMS2_k127_3242563_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 4.11e-248 768.0
CMS2_k127_3242563_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002477 227.0
CMS2_k127_3242563_23 COG2346, Truncated hemoglobins K06886 - - 0.000000000000000000000000000000000000000000000000000000000000002558 218.0
CMS2_k127_3242563_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000003482 215.0
CMS2_k127_3242563_25 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.00000000000000000000000000000000000000000000000000000000005888 205.0
CMS2_k127_3242563_26 - - - - 0.000000000000000000000000000000000000000000000000000000001868 201.0
CMS2_k127_3242563_27 -acetyltransferase K06975 - - 0.0000000000000000000000000000000000000000000000001814 178.0
CMS2_k127_3242563_28 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K02573,K13795,K18930 - 1.2.7.1 0.000000000000000000000000000000000000000000000023 169.0
CMS2_k127_3242563_29 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000888 169.0
CMS2_k127_3242563_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.554e-244 764.0
CMS2_k127_3242563_30 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000001067 153.0
CMS2_k127_3242563_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 601.0
CMS2_k127_3242563_5 cofactor biosynthesis protein NifE K02587 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 567.0
CMS2_k127_3242563_6 COGs COG3864 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 572.0
CMS2_k127_3242563_7 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 567.0
CMS2_k127_3242563_8 phosphate ion binding K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 488.0
CMS2_k127_3242563_9 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 440.0
CMS2_k127_3321106_0 PFAM biotin lipoyl attachment domain-containing protein K01960 - 6.4.1.1 0.0 1181.0
CMS2_k127_3321106_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.0 1090.0
CMS2_k127_3321106_2 DEAD DEAH box helicase K05592 - 3.6.4.13 8.285e-286 879.0
CMS2_k127_3321106_3 COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit K01572 - 4.1.1.3 6.865e-263 813.0
CMS2_k127_3321106_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 461.0
CMS2_k127_3321106_5 sodium ion export across plasma membrane K01573 GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234 4.1.1.3 0.0000000000000000000000000625 108.0
CMS2_k127_3321106_6 ABC-type multidrug transport system ATPase and permease K06148 - - 0.0000000000000000000000003956 104.0
CMS2_k127_3325126_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 488.0
CMS2_k127_3325126_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 437.0
CMS2_k127_3325126_2 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001667 277.0
CMS2_k127_3325126_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006961 240.0
CMS2_k127_3325126_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000000000000006287 211.0
CMS2_k127_3325126_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000000001681 194.0
CMS2_k127_3325126_6 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000000000004322 161.0
CMS2_k127_3325126_7 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000002403 55.0
CMS2_k127_3337220_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K16881 - 2.7.7.13,5.4.2.8 0.0 1612.0
CMS2_k127_3337220_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1349.0
CMS2_k127_3337220_10 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 587.0
CMS2_k127_3337220_11 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 467.0
CMS2_k127_3337220_12 COG1252 NADH dehydrogenase FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 317.0
CMS2_k127_3337220_13 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000001136 210.0
CMS2_k127_3337220_14 - - - - 0.000000000000000000000000000000008994 129.0
CMS2_k127_3337220_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1324.0
CMS2_k127_3337220_3 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0 1312.0
CMS2_k127_3337220_4 Acyl-CoA dehydrogenase, N-terminal domain K14448 - 1.3.8.12 0.0 1032.0
CMS2_k127_3337220_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.234e-312 959.0
CMS2_k127_3337220_6 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.567e-292 899.0
CMS2_k127_3337220_7 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.262e-273 859.0
CMS2_k127_3337220_8 Serine aminopeptidase, S33 - - - 1.057e-261 824.0
CMS2_k127_3337220_9 Belongs to the thiolase family K00626 - 2.3.1.9 2.634e-207 651.0
CMS2_k127_3354185_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 342.0
CMS2_k127_3354185_2 Transglutaminase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 336.0
CMS2_k127_3381716_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1102.0
CMS2_k127_3381716_1 Aminotransferase K14261 - - 5.581e-267 822.0
CMS2_k127_3381716_2 Major facilitator superfamily K08177 - - 8.013e-252 779.0
CMS2_k127_3381716_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 500.0
CMS2_k127_3381716_4 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 308.0
CMS2_k127_3381716_5 - - - - 0.0000000000000000000000000000000000000000000000604 169.0
CMS2_k127_34049_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 1.229e-236 737.0
CMS2_k127_34049_1 Permease, YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 567.0
CMS2_k127_34049_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 432.0
CMS2_k127_34049_3 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 368.0
CMS2_k127_34049_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 302.0
CMS2_k127_34049_5 membrane K08973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002221 277.0
CMS2_k127_34049_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000001753 218.0
CMS2_k127_34049_7 cytochrome c class I - - - 0.0000000000000000000000000000000000000000000000000000000001312 205.0
CMS2_k127_34049_8 Peptidase A24 K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000004513 204.0
CMS2_k127_3410072_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 599.0
CMS2_k127_3410072_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 587.0
CMS2_k127_3410072_2 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 377.0
CMS2_k127_3410072_3 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 368.0
CMS2_k127_3410072_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 357.0
CMS2_k127_3410072_6 (HIT) family - - - 0.00000000000005343 72.0
CMS2_k127_3412901_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1140.0
CMS2_k127_3412901_1 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.0 1134.0
CMS2_k127_3412901_10 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 536.0
CMS2_k127_3412901_11 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 531.0
CMS2_k127_3412901_12 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 458.0
CMS2_k127_3412901_13 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 456.0
CMS2_k127_3412901_14 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 380.0
CMS2_k127_3412901_15 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 379.0
CMS2_k127_3412901_17 protein conserved in bacteria K09804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 360.0
CMS2_k127_3412901_19 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007516 250.0
CMS2_k127_3412901_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.089e-320 982.0
CMS2_k127_3412901_20 cytochrome c oxidase K00407 - - 0.00000000000000000000000000000000000000251 146.0
CMS2_k127_3412901_22 FixH - - - 0.00000000000549 73.0
CMS2_k127_3412901_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.146e-271 836.0
CMS2_k127_3412901_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 3.763e-256 791.0
CMS2_k127_3412901_5 Belongs to the CarA family K01956 - 6.3.5.5 5.899e-226 702.0
CMS2_k127_3412901_6 COG3893 inactivated superfamily I helicase - - - 3.482e-224 698.0
CMS2_k127_3412901_7 Aminotransferase - - - 5.039e-224 696.0
CMS2_k127_3412901_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 5.378e-212 660.0
CMS2_k127_3412901_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 547.0
CMS2_k127_34939_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.143e-290 894.0
CMS2_k127_34939_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 1.565e-195 611.0
CMS2_k127_34939_2 Fumarate hydratase K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 550.0
CMS2_k127_34939_3 Fumarate K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 364.0
CMS2_k127_34939_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 283.0
CMS2_k127_34939_5 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000009539 162.0
CMS2_k127_3501211_0 COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 605.0
CMS2_k127_3501211_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 534.0
CMS2_k127_3501211_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 372.0
CMS2_k127_3501211_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003186 236.0
CMS2_k127_3551429_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 7.649e-236 730.0
CMS2_k127_3551429_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 1.728e-211 658.0
CMS2_k127_3551429_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001035 277.0
CMS2_k127_3551429_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000006044 97.0
CMS2_k127_3681799_0 - - - - 5.36e-199 622.0
CMS2_k127_3681799_1 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 473.0
CMS2_k127_3681799_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 451.0
CMS2_k127_3681799_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000001179 237.0
CMS2_k127_3681799_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000000000000000000000006308 229.0
CMS2_k127_3681799_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000001481 153.0
CMS2_k127_3681799_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000001211 154.0
CMS2_k127_3692795_0 Cytochrome c oxidase accessory protein - - - 3.061e-305 936.0
CMS2_k127_3692795_1 Fad-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 7.44e-236 731.0
CMS2_k127_3692795_2 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 359.0
CMS2_k127_3692795_3 PFAM Resolvase, N terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 352.0
CMS2_k127_3692795_4 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 338.0
CMS2_k127_3692795_5 Paraquat-inducible protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 331.0
CMS2_k127_3692795_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 299.0
CMS2_k127_3692795_7 Protein of unknown function (DUF493) - - - 0.0000000000000000000000000000000000000000000000000008578 183.0
CMS2_k127_3696544_0 PFAM MOFRL domain protein K11529 - 2.7.1.165 1.337e-213 666.0
CMS2_k127_3696544_1 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 517.0
CMS2_k127_3696544_2 HAD-superfamily hydrolase, subfamily IIB K07026,K15918 - 2.7.1.31,3.1.3.70 0.00000000000000000000000000000000000000000000000000000000000000004455 231.0
CMS2_k127_3728943_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 311.0
CMS2_k127_3728943_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000001147 252.0
CMS2_k127_3728943_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000003303 238.0
CMS2_k127_3728943_3 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000005951 199.0
CMS2_k127_3728943_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000471 192.0
CMS2_k127_3728943_5 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000006443 170.0
CMS2_k127_3728943_6 Chaperone for flagella basal body P-ring formation K02386 - - 0.00000000000000000000000000003103 128.0
CMS2_k127_3728943_7 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000001444 77.0
CMS2_k127_3731936_0 cation transport ATPase K01533,K17686 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.4,3.6.3.54 0.0 1399.0
CMS2_k127_3731936_1 Multi-copper - - - 0.0 1280.0
CMS2_k127_3731936_10 Protoglobin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 567.0
CMS2_k127_3731936_11 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 529.0
CMS2_k127_3731936_12 COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 492.0
CMS2_k127_3731936_13 Small subunit K05927 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 293.0
CMS2_k127_3731936_14 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003745 274.0
CMS2_k127_3731936_15 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009445 238.0
CMS2_k127_3731936_16 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000008571 239.0
CMS2_k127_3731936_18 - - - - 0.00000000000000000000000000000000000000002327 154.0
CMS2_k127_3731936_19 Protein of unknown function, DUF255 - - - 0.000000000000000121 84.0
CMS2_k127_3731936_2 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 - - 9.414e-311 952.0
CMS2_k127_3731936_20 membrane protein (DUF2078) K08982 - - 0.000000002424 58.0
CMS2_k127_3731936_3 Na Pi-cotransporter K03324 - - 1.57e-303 937.0
CMS2_k127_3731936_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 2.966e-298 917.0
CMS2_k127_3731936_5 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 4.895e-298 936.0
CMS2_k127_3731936_6 pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 6.182e-289 891.0
CMS2_k127_3731936_7 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09015 - - 5.485e-242 749.0
CMS2_k127_3731936_8 Mycolic acid cyclopropane synthetase - - - 3.958e-208 655.0
CMS2_k127_3731936_9 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 584.0
CMS2_k127_3737081_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 539.0
CMS2_k127_3737081_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 383.0
CMS2_k127_3737081_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000002331 220.0
CMS2_k127_3824464_0 DNA helicase K03657 - 3.6.4.12 0.0 1326.0
CMS2_k127_3824464_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1117.0
CMS2_k127_3824464_10 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 388.0
CMS2_k127_3824464_11 protein conserved in bacteria K09928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 326.0
CMS2_k127_3824464_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 315.0
CMS2_k127_3824464_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002383 221.0
CMS2_k127_3824464_2 Belongs to the DNA photolyase family K01669 - 4.1.99.3 1.455e-272 841.0
CMS2_k127_3824464_3 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 8.129e-268 827.0
CMS2_k127_3824464_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.398e-260 804.0
CMS2_k127_3824464_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 597.0
CMS2_k127_3824464_6 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 566.0
CMS2_k127_3824464_7 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 511.0
CMS2_k127_3824464_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 509.0
CMS2_k127_3824464_9 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 408.0
CMS2_k127_3853688_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.017e-206 643.0
CMS2_k127_3853688_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 340.0
CMS2_k127_3879603_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 7.389e-258 795.0
CMS2_k127_3879603_1 Ggdef domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 327.0
CMS2_k127_3879603_2 - - - - 0.000000000000000000000000000000000006546 136.0
CMS2_k127_3899052_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1781.0
CMS2_k127_3899052_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 346.0
CMS2_k127_394515_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 1.7e-203 635.0
CMS2_k127_394515_1 hmm pf01205 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001462 266.0
CMS2_k127_394515_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000008547 76.0
CMS2_k127_395987_0 Conserved region in glutamate synthase - - - 0.0 1092.0
CMS2_k127_395987_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 1.362e-225 702.0
CMS2_k127_395987_2 Histidine kinase K02484 - 2.7.13.3 4.289e-201 631.0
CMS2_k127_395987_3 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 428.0
CMS2_k127_395987_4 - K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 331.0
CMS2_k127_395987_5 DoxX family K15977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003333 254.0
CMS2_k127_395987_6 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001267 244.0
CMS2_k127_395987_9 - - - - 0.000000000000000000000000000000000001855 139.0
CMS2_k127_3968227_0 phosphohydrolase (DHH superfamily) K07097 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 596.0
CMS2_k127_3968227_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007447 255.0
CMS2_k127_3968227_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000785 66.0
CMS2_k127_3993103_0 ATPase (AAA - - - 0.0 1101.0
CMS2_k127_3993103_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 1.262e-304 942.0
CMS2_k127_3993103_10 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000004391 145.0
CMS2_k127_3993103_11 NADH dehydrogenase (ubiquinone) activity K00330 - 1.6.5.3 0.00000000000000002006 87.0
CMS2_k127_3993103_2 COG0642 Signal transduction histidine kinase K02484 - 2.7.13.3 2.083e-205 641.0
CMS2_k127_3993103_3 Amidohydrolase family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 520.0
CMS2_k127_3993103_5 phosphotransferase system, EIIB K02802,K02803,K02804 - 2.7.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 454.0
CMS2_k127_3993103_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 370.0
CMS2_k127_3993103_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 313.0
CMS2_k127_3993103_8 pts system K02777 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009892,GO:0009898,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045912,GO:0048519,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071944,GO:0080090,GO:0098552,GO:0098562 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 288.0
CMS2_k127_3993103_9 COG0607 Rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005017 254.0
CMS2_k127_4006148_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 361.0
CMS2_k127_4006148_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 328.0
CMS2_k127_4006148_2 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 285.0
CMS2_k127_4006148_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001228 260.0
CMS2_k127_4006148_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000000000000000001647 224.0
CMS2_k127_4006148_5 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000001616 151.0
CMS2_k127_4006148_6 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000001549 126.0
CMS2_k127_4006148_7 Binds to the 23S rRNA K02876 - - 0.000000000000000000005403 92.0
CMS2_k127_4049126_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006387 228.0
CMS2_k127_4049126_1 - - - - 0.00000000000000000000000000000000001373 144.0
CMS2_k127_4056471_0 Participates in both transcription termination and antitermination K02600 - - 2.941e-232 721.0
CMS2_k127_4056471_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 3.909e-224 695.0
CMS2_k127_4056471_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 289.0
CMS2_k127_4056471_3 - - - - 0.00000000000000000000000000000000000000003298 152.0
CMS2_k127_4064101_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 8.155e-317 971.0
CMS2_k127_4064101_1 Domain of unknown function (DUF4139) - - - 1.422e-223 700.0
CMS2_k127_4064101_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 2.901e-205 639.0
CMS2_k127_4064101_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 546.0
CMS2_k127_4064101_4 Conserved Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 394.0
CMS2_k127_4064101_5 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 298.0
CMS2_k127_4064101_6 serine-type aminopeptidase activity K02030,K14475 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 292.0
CMS2_k127_4064101_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000005775 220.0
CMS2_k127_4064101_8 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000002009 214.0
CMS2_k127_4064101_9 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000000000004838 151.0
CMS2_k127_4076255_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 1.903e-222 691.0
CMS2_k127_4076255_1 Fibronectin fibrinogen-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 494.0
CMS2_k127_4076255_2 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 478.0
CMS2_k127_4076255_3 esterase of the alpha beta hydrolase fold K07002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002685 247.0
CMS2_k127_4076255_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000001508 81.0
CMS2_k127_4076706_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0 1108.0
CMS2_k127_4076706_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 2.137e-215 670.0
CMS2_k127_4076706_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 1.095e-200 626.0
CMS2_k127_4076706_3 metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 553.0
CMS2_k127_4076706_4 metal-binding, possibly nucleic acid-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000291 241.0
CMS2_k127_4076706_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000001663 209.0
CMS2_k127_4076706_6 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000007887 115.0
CMS2_k127_4078290_0 Belongs to the DNA mismatch repair MutS family K03555 - - 0.0 1823.0
CMS2_k127_4078290_1 Oxidoreductase K06151 - 1.1.99.3 0.0 1116.0
CMS2_k127_4078290_11 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000000005081 121.0
CMS2_k127_4078290_12 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000002092 93.0
CMS2_k127_4078290_15 - - - - 0.00001005 49.0
CMS2_k127_4078290_16 - - - - 0.0001178 46.0
CMS2_k127_4078290_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1101.0
CMS2_k127_4078290_3 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 523.0
CMS2_k127_4078290_4 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 517.0
CMS2_k127_4078290_5 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 484.0
CMS2_k127_4078290_6 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 282.0
CMS2_k127_4078290_7 DoxX family K15977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003822 267.0
CMS2_k127_4078290_9 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000000000000006735 222.0
CMS2_k127_4087181_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 3.536e-306 939.0
CMS2_k127_4087181_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 2.502e-227 705.0
CMS2_k127_4087181_10 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000477 241.0
CMS2_k127_4087181_11 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001495 233.0
CMS2_k127_4087181_12 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000000000000000000000000000000000000002044 222.0
CMS2_k127_4087181_13 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000002024 216.0
CMS2_k127_4087181_14 Belongs to the ArsC family - - - 0.0000000000000000000000000000000000000000000000000000000001491 204.0
CMS2_k127_4087181_15 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000001199 181.0
CMS2_k127_4087181_16 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000001869 174.0
CMS2_k127_4087181_17 phosphate-selective porin O and P - - - 0.000000005706 59.0
CMS2_k127_4087181_2 twitching motility protein K02669 - - 3.744e-222 690.0
CMS2_k127_4087181_3 transmembrane signaling receptor activity - - - 1.889e-217 677.0
CMS2_k127_4087181_4 Histidine kinase - - - 2.174e-212 663.0
CMS2_k127_4087181_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 601.0
CMS2_k127_4087181_6 Uncharacterised protein family (UPF0227) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 351.0
CMS2_k127_4087181_7 membrane protein, required for colicin V production K03558 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 353.0
CMS2_k127_4087181_8 Belongs to the Fur family K03711 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 292.0
CMS2_k127_4087181_9 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008108 260.0
CMS2_k127_4092188_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 1.197e-232 722.0
CMS2_k127_4092188_1 phosphate ion binding K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 455.0
CMS2_k127_4092188_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007543 275.0
CMS2_k127_4100240_0 Diguanylate cyclase - - - 0.0 1319.0
CMS2_k127_4100240_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0 1003.0
CMS2_k127_4100240_3 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 8.394e-259 799.0
CMS2_k127_4106376_0 Belongs to the AAA ATPase family - - - 0.0 1004.0
CMS2_k127_4106376_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03316 - - 6.579e-316 974.0
CMS2_k127_4106376_10 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 433.0
CMS2_k127_4106376_11 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 368.0
CMS2_k127_4106376_12 Highly conserved protein containing a thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 364.0
CMS2_k127_4106376_13 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 286.0
CMS2_k127_4106376_14 ADP-ribose pyrophosphatase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000002959 258.0
CMS2_k127_4106376_15 Putative integral membrane protein (DUF2391) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002765 236.0
CMS2_k127_4106376_16 endonuclease III K07457 - - 0.0000000000000000000000000000000001931 132.0
CMS2_k127_4106376_2 mechanosensitive ion channel - - - 1.605e-315 971.0
CMS2_k127_4106376_3 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 2.935e-275 853.0
CMS2_k127_4106376_4 domain protein K09944 - - 1.183e-246 767.0
CMS2_k127_4106376_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 3.566e-241 749.0
CMS2_k127_4106376_6 MiaB-like tRNA modifying enzyme - - - 1.55e-238 741.0
CMS2_k127_4106376_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 2.503e-217 676.0
CMS2_k127_4106376_8 acid membrane antigen A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 561.0
CMS2_k127_4106376_9 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 497.0
CMS2_k127_4109046_0 Sulfite dehydrogenase (Cytochrome) subunit SorA apoprotein K07147 - - 2.684e-257 795.0
CMS2_k127_4109046_1 Peptidase family M41 - - - 2.5e-245 762.0
CMS2_k127_4109046_10 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000000000000000000004143 130.0
CMS2_k127_4109046_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.0005076 46.0
CMS2_k127_4109046_2 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 457.0
CMS2_k127_4109046_3 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 383.0
CMS2_k127_4109046_5 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 354.0
CMS2_k127_4109046_6 Protein of unknown function (DUF2459) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 343.0
CMS2_k127_4109046_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 330.0
CMS2_k127_4109046_8 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000000000000003048 229.0
CMS2_k127_4109046_9 cytochrome C oxidoreductase subunit B - - - 0.0000000000000000000000000000000000000000000003007 168.0
CMS2_k127_4115436_0 Belongs to the peptidase S1C family - - - 9.699e-297 912.0
CMS2_k127_4115436_1 Belongs to the aldehyde dehydrogenase family - - - 8.302e-294 904.0
CMS2_k127_4115436_10 Conserved Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001603 269.0
CMS2_k127_4115436_11 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000001119 222.0
CMS2_k127_4115436_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.228e-292 897.0
CMS2_k127_4115436_3 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 2.154e-207 647.0
CMS2_k127_4115436_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 6.527e-196 611.0
CMS2_k127_4115436_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 495.0
CMS2_k127_4115436_6 General glycosylation pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 492.0
CMS2_k127_4115436_7 Prolyl 4-hydroxylase alpha subunit homologues. K07394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 430.0
CMS2_k127_4115436_8 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 422.0
CMS2_k127_4115436_9 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 287.0
CMS2_k127_4127272_0 Highly conserved protein containing a thioredoxin domain K06888 - - 1.03e-270 847.0
CMS2_k127_4127272_1 TIGRFAM SagB-type dehydrogenase domain - - - 6.821e-243 754.0
CMS2_k127_4127272_2 phage repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 424.0
CMS2_k127_4127272_3 molybdopterin biosynthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000005494 187.0
CMS2_k127_4127272_4 Translation initiation factor SUI1 K03113 - - 0.000000000000000000000000000000000000000000000000002429 183.0
CMS2_k127_4127272_5 Domain of unknown function (DUF309) K09763 - - 0.00000000000000000000000000000000000000000002586 163.0
CMS2_k127_4127272_6 Belongs to the UPF0246 family K09861 - - 0.000000000000000000000000000000379 122.0
CMS2_k127_4129365_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 1.156e-274 848.0
CMS2_k127_4129365_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 1.805e-244 756.0
CMS2_k127_4129365_2 Belongs to the peptidase M50B family - - - 1.321e-212 663.0
CMS2_k127_4129365_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 543.0
CMS2_k127_4129365_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 486.0
CMS2_k127_4129365_5 PFAM Amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 388.0
CMS2_k127_4129365_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 321.0
CMS2_k127_4129365_7 2'-5' RNA ligase K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 301.0
CMS2_k127_4129365_8 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000000000000000000003713 178.0
CMS2_k127_4129365_9 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000000008247 133.0
CMS2_k127_4149175_0 General glycosylation pathway protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 541.0
CMS2_k127_4149175_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 533.0
CMS2_k127_4149175_2 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 471.0
CMS2_k127_4149175_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 384.0
CMS2_k127_4149175_4 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000006521 130.0
CMS2_k127_4183372_0 Mitochondrial degradasome RNA helicase subunit C terminal K17675 - 3.6.4.13 0.0 1184.0
CMS2_k127_4183372_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 8.157e-258 797.0
CMS2_k127_4183372_2 Phospholipase D. Active site motifs. K06131 - - 4.015e-257 797.0
CMS2_k127_4183372_3 Pseudouridine synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 505.0
CMS2_k127_4183372_4 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 389.0
CMS2_k127_4183372_5 COG0071 Molecular chaperone (small heat shock protein) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 347.0
CMS2_k127_4183372_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008098 268.0
CMS2_k127_4183372_7 Pfam:DUF1049 - - - 0.0000000000000000000000003277 105.0
CMS2_k127_4183821_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1300.0
CMS2_k127_4183821_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.378e-239 745.0
CMS2_k127_4183821_10 endonuclease containing a URI domain K07461 - - 0.00000000000000000000000000000000000004693 143.0
CMS2_k127_4183821_11 - - - - 0.00000000000000000000000000000002725 126.0
CMS2_k127_4183821_2 lytic murein transglycosylase K08309 - - 1.925e-237 738.0
CMS2_k127_4183821_3 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 578.0
CMS2_k127_4183821_4 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 549.0
CMS2_k127_4183821_6 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 303.0
CMS2_k127_4183821_7 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004418 276.0
CMS2_k127_4183821_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001283 265.0
CMS2_k127_4183821_9 YGGT family K02221 - - 0.00000000000000000000000000000000000000000000002987 171.0
CMS2_k127_4191262_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1014.0
CMS2_k127_4191262_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 599.0
CMS2_k127_4191262_2 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 399.0
CMS2_k127_4191262_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 372.0
CMS2_k127_4191262_4 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 358.0
CMS2_k127_4194807_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 1.688e-200 627.0
CMS2_k127_4194807_1 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 583.0
CMS2_k127_4194807_2 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 303.0
CMS2_k127_4194807_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000002738 236.0
CMS2_k127_4194807_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000009394 169.0
CMS2_k127_4194807_5 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000105 109.0
CMS2_k127_4194807_6 lipopolysaccharide core region biosynthetic process - - - 0.0000000000000000000000001716 109.0
CMS2_k127_4199515_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 0.0 1510.0
CMS2_k127_4199515_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000599 279.0
CMS2_k127_4199515_2 COG3893 inactivated superfamily I helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000787 273.0
CMS2_k127_4199515_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000005157 80.0
CMS2_k127_4228787_0 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 0.0 1311.0
CMS2_k127_4228787_1 Belongs to the FtsK SpoIIIE SftA family K03466 - - 2.216e-235 730.0
CMS2_k127_4228787_2 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 407.0
CMS2_k127_4228787_4 thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000002331 230.0
CMS2_k127_4228974_0 general secretion pathway protein D K02453 - - 8.354e-316 970.0
CMS2_k127_4228974_1 proline dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 532.0
CMS2_k127_4228974_2 COG1459 Type II secretory pathway, component PulF K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 484.0
CMS2_k127_4228974_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 336.0
CMS2_k127_4228974_4 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 280.0
CMS2_k127_4228974_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004042 276.0
CMS2_k127_4228974_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000183 238.0
CMS2_k127_4228974_7 General secretion pathway protein C K02452 - - 0.000004317 57.0
CMS2_k127_4232006_0 Mediates zinc uptake. May also transport other divalent cations K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 493.0
CMS2_k127_4232006_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 486.0
CMS2_k127_4232006_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 376.0
CMS2_k127_4232006_3 Ferritin K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 328.0
CMS2_k127_4232006_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000001651 96.0
CMS2_k127_4234359_0 Cache domain - - - 1.353e-279 865.0
CMS2_k127_4234359_1 HI0933-like protein K07007 - - 9.072e-249 771.0
CMS2_k127_4234359_10 EF hand - - - 0.0000000000000000000000000000000000000000000002089 168.0
CMS2_k127_4234359_11 - - - - 0.000000000000000000000000000000000000252 141.0
CMS2_k127_4234359_14 - - - - 0.000000000000000002378 85.0
CMS2_k127_4234359_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 553.0
CMS2_k127_4234359_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 411.0
CMS2_k127_4234359_4 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 383.0
CMS2_k127_4234359_5 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 359.0
CMS2_k127_4234359_6 Cytochrome c family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 326.0
CMS2_k127_4234359_7 EF hand - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 308.0
CMS2_k127_4234359_8 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008114 234.0
CMS2_k127_4234359_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000004545 216.0
CMS2_k127_4236134_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 328.0
CMS2_k127_4236134_1 lyase activity - - - 0.000000000000000000000000000000000000000000000000000004241 193.0
CMS2_k127_4236134_2 - - - - 0.0000000000000000000000000000001963 124.0
CMS2_k127_4240437_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 3.187e-210 656.0
CMS2_k127_4240437_1 coproporphyrinogen III oxidase K00228 GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 1.881e-203 635.0
CMS2_k127_4240437_2 K -dependent Na Ca exchanger K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 542.0
CMS2_k127_4240437_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 411.0
CMS2_k127_4240437_4 GlutRNAGln amidotransferase subunit D K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 316.0
CMS2_k127_4240437_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001273 261.0
CMS2_k127_4240437_7 penicillin-binding protein K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000002164 191.0
CMS2_k127_42415_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1400.0
CMS2_k127_4292337_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1373.0
CMS2_k127_4292337_1 PFAM Bacterial transcription activator, effector binding domain K13652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 427.0
CMS2_k127_4292337_2 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 425.0
CMS2_k127_4292337_3 Belongs to the P(II) protein family - - - 0.00000000000000000000009645 101.0
CMS2_k127_429389_0 sulfur dehydrogenase subunit K17225 - - 1.49e-223 700.0
CMS2_k127_429389_1 Cytochrome c K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 412.0
CMS2_k127_429389_2 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000005466 182.0
CMS2_k127_429389_3 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000006132 161.0
CMS2_k127_429389_4 Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000000001408 146.0
CMS2_k127_429389_5 Thioredoxin-like domain - - - 0.000000000000000000000136 104.0
CMS2_k127_4310415_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0 1142.0
CMS2_k127_4310415_1 Phospholipid glycerol acyltransferase - - - 0.0 1046.0
CMS2_k127_4310415_10 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 341.0
CMS2_k127_4310415_11 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 331.0
CMS2_k127_4310415_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 316.0
CMS2_k127_4310415_13 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005354 259.0
CMS2_k127_4310415_14 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000001662 128.0
CMS2_k127_4310415_15 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 4.2.3.5 0.000000000000000000000000000001669 120.0
CMS2_k127_4310415_17 Parallel beta-helix repeats - - - 0.0000000000000617 78.0
CMS2_k127_4310415_2 CarboxypepD_reg-like domain - - - 1.2e-322 1017.0
CMS2_k127_4310415_3 phosphate transporter K03306 - - 5.16e-259 805.0
CMS2_k127_4310415_4 MotA TolQ ExbB proton channel K03561 - - 7.119e-247 766.0
CMS2_k127_4310415_5 Tetratricopeptide repeat - - - 3.658e-244 757.0
CMS2_k127_4310415_6 - K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 527.0
CMS2_k127_4310415_7 Protein of unknown function (DUF3450) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 429.0
CMS2_k127_4310415_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 394.0
CMS2_k127_4310415_9 MotA TolQ ExbB proton channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 371.0
CMS2_k127_4313476_0 TRAP transporter, DctM subunit - - - 0.0 1078.0
CMS2_k127_4313476_1 ATPase family associated with various cellular activities (AAA) K03924 - - 1.337e-195 612.0
CMS2_k127_4313476_2 Fructosamine kinase - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 295.0
CMS2_k127_4313476_3 cytidine deaminase activity K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000009992 246.0
CMS2_k127_4313476_4 belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000000000000000003319 224.0
CMS2_k127_4313476_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000007054 213.0
CMS2_k127_4313476_7 - - - - 0.0000000000000000000000000000000000009314 139.0
CMS2_k127_4323777_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1176.0
CMS2_k127_4323777_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 9.112e-226 700.0
CMS2_k127_4323777_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000002523 84.0
CMS2_k127_4332689_0 Belongs to the NifD NifK NifE NifN family K02592 - - 2.11e-208 655.0
CMS2_k127_4332689_1 cofactor biosynthesis protein NifE K02587 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 303.0
CMS2_k127_4332689_2 Low-potential electron donor to a number of redox enzymes K03839 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006624 274.0
CMS2_k127_4332689_3 Nitrogen fixation protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004114 240.0
CMS2_k127_4332689_4 Nitrogen fixation protein NifW K02595 - - 0.000000000000000000000000000000000000000000000000000000000005965 209.0
CMS2_k127_4332689_5 Dinitrogenase iron-molybdenum cofactor biosynthesis protein K02596 - - 0.000000000000000000000000000000000000000000000000000000000463 207.0
CMS2_k127_4332689_6 NifZ domain K02597 - - 0.000000000000000009361 87.0
CMS2_k127_4332689_7 Ferredoxin - - - 0.0000000000000135 73.0
CMS2_k127_4350332_0 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 480.0
CMS2_k127_4350332_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 437.0
CMS2_k127_4350332_2 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009644 276.0
CMS2_k127_4350332_3 Domain of unknown function DUF302 - - - 0.000000000000000000000000002748 116.0
CMS2_k127_4360968_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1141.0
CMS2_k127_4360968_1 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 567.0
CMS2_k127_4360968_2 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 433.0
CMS2_k127_4360968_3 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000008955 236.0
CMS2_k127_4360968_6 lipoprotein - - - 0.000000000000000000000000000000000001196 139.0
CMS2_k127_438138_0 ABC transporter K11085 - - 8.333e-313 964.0
CMS2_k127_438138_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 8.604e-249 769.0
CMS2_k127_438138_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 2.847e-227 705.0
CMS2_k127_438138_4 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000007225 206.0
CMS2_k127_4396042_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 0.0 1151.0
CMS2_k127_4396042_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 3.551e-314 964.0
CMS2_k127_4396042_2 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 528.0
CMS2_k127_4396042_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 434.0
CMS2_k127_4396042_4 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 374.0
CMS2_k127_4396042_5 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000001699 211.0
CMS2_k127_4401177_0 fructose-bisphosphate aldolase K01624 - 4.1.2.13 4.805e-233 721.0
CMS2_k127_4401177_1 1-aminocyclopropane-1-carboxylate deaminase K01505 - 3.5.99.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 525.0
CMS2_k127_4401177_2 peptidylprolyl isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 505.0
CMS2_k127_4401177_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 387.0
CMS2_k127_4401177_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 336.0
CMS2_k127_4428615_0 permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 521.0
CMS2_k127_4428615_1 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 335.0
CMS2_k127_4428615_2 Sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003141 254.0
CMS2_k127_4428615_3 Redox-active disulfide protein - - - 0.0000000000000000000000000000004236 124.0
CMS2_k127_4452749_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 9.074e-225 698.0
CMS2_k127_4452749_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 3.463e-211 658.0
CMS2_k127_4452749_2 abc transporter atp-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 417.0
CMS2_k127_4452749_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005831 274.0
CMS2_k127_4452749_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000001023 231.0
CMS2_k127_4509294_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 8.679e-319 979.0
CMS2_k127_4537251_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 442.0
CMS2_k127_4537251_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 364.0
CMS2_k127_4537251_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000002931 52.0
CMS2_k127_4545877_0 dna polymerase iii K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 481.0
CMS2_k127_4545877_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 415.0
CMS2_k127_4545877_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000001229 206.0
CMS2_k127_4555274_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 8.159e-218 677.0
CMS2_k127_4555274_1 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008282 396.0
CMS2_k127_4555404_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1590.0
CMS2_k127_4555404_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.806e-321 989.0
CMS2_k127_4555404_10 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 396.0
CMS2_k127_4555404_11 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 383.0
CMS2_k127_4555404_12 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000405 277.0
CMS2_k127_4555404_13 COG1214 Inactive homolog of metal-dependent proteases - - - 0.00000000000000000000000000000000000000000000000000000000000000002823 226.0
CMS2_k127_4555404_14 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000000000001097 210.0
CMS2_k127_4555404_15 Ferredoxin K05337 - - 0.0000000000000000000000000000000000000000000000001027 177.0
CMS2_k127_4555404_16 nucleic-acid-binding protein implicated in transcription termination - - - 0.000000000000000000000000000000000000000000002271 165.0
CMS2_k127_4555404_17 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000002716 149.0
CMS2_k127_4555404_2 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 7.774e-305 937.0
CMS2_k127_4555404_3 peptidase M23 - - - 2.386e-260 806.0
CMS2_k127_4555404_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 8.826e-220 682.0
CMS2_k127_4555404_5 riboflavin biosynthesis protein K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 606.0
CMS2_k127_4555404_6 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 576.0
CMS2_k127_4555404_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 568.0
CMS2_k127_4555404_8 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 491.0
CMS2_k127_4555404_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 434.0
CMS2_k127_4570528_0 Cytochrome c biogenesis protein - - - 0.0 1927.0
CMS2_k127_4570528_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1688.0
CMS2_k127_4570528_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 536.0
CMS2_k127_4570528_3 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 482.0
CMS2_k127_4570528_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003796 276.0
CMS2_k127_4570528_5 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001685 266.0
CMS2_k127_4572482_0 TonB-dependent copper receptor K02014 - - 0.0 1041.0
CMS2_k127_4572482_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 563.0
CMS2_k127_4572482_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 349.0
CMS2_k127_4572482_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000000252 141.0
CMS2_k127_4572824_0 COG0659 Sulfate permease and related K03321 - - 1.51e-290 898.0
CMS2_k127_4572824_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 488.0
CMS2_k127_4572824_2 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 424.0
CMS2_k127_4572824_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 418.0
CMS2_k127_4572824_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 402.0
CMS2_k127_4572824_5 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 360.0
CMS2_k127_4572824_6 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 348.0
CMS2_k127_4572824_7 carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000008507 235.0
CMS2_k127_4572824_8 - - - - 0.00000000000000000000000000000403 120.0
CMS2_k127_4572824_9 Domain of unknown function (DUF4918) - - - 0.0000000000000000000001453 97.0
CMS2_k127_4574306_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 439.0
CMS2_k127_4574306_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 427.0
CMS2_k127_4574306_2 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000001913 243.0
CMS2_k127_458536_0 Ammonium Transporter K03320 - - 5.383e-274 844.0
CMS2_k127_458536_1 Ammonium Transporter K03320 - - 9.163e-243 752.0
CMS2_k127_458536_2 PFAM Archaea bacterial proteins of K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 540.0
CMS2_k127_458536_3 Molybdopterin oxidoreductase Fe4S4 domain K00372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 486.0
CMS2_k127_458536_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 465.0
CMS2_k127_458536_5 hmm pf01205 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 337.0
CMS2_k127_458536_6 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000000000004801 222.0
CMS2_k127_458536_7 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000000000002331 220.0
CMS2_k127_458536_8 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000007299 190.0
CMS2_k127_458536_9 Histidine kinase - - - 0.000000000000000000000000000000002086 138.0
CMS2_k127_4637404_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 1.981e-248 769.0
CMS2_k127_4637404_1 PFAM secretion protein HlyD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 363.0
CMS2_k127_4646740_0 Glycolate oxidase subunit K00104 - 1.1.3.15 4.83e-291 895.0
CMS2_k127_4646740_1 peptidase M23 - - - 9.536e-240 745.0
CMS2_k127_4646740_2 Plasminogen-binding protein pgbA N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 413.0
CMS2_k127_4646740_3 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 355.0
CMS2_k127_4659723_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 417.0
CMS2_k127_4659723_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 313.0
CMS2_k127_4659723_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K02573,K13795,K18930 - 1.2.7.1 0.000000000000000000000000000000000000000005276 154.0
CMS2_k127_4661113_0 transporter K14445 - - 1.203e-243 758.0
CMS2_k127_4661113_1 hydrogenase expression formation protein K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 507.0
CMS2_k127_4661113_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000000000000000000000000000001684 223.0
CMS2_k127_47518_0 Paraquat-inducible protein B - - - 9.495e-300 923.0
CMS2_k127_47518_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 536.0
CMS2_k127_47518_2 Paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 377.0
CMS2_k127_47518_3 paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 376.0
CMS2_k127_47518_4 ABC-type transport auxiliary lipoprotein component K02067,K09857,K18480 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 294.0
CMS2_k127_4759852_0 COG2200 FOG EAL domain - - - 6.916e-194 610.0
CMS2_k127_4759852_1 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 602.0
CMS2_k127_4759852_2 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 473.0
CMS2_k127_4759852_3 Belongs to the globin family K05916 - 1.14.12.17 0.000000000000000000000000000000000000000000000000000000000000000000000000005375 253.0
CMS2_k127_4766533_0 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0 1236.0
CMS2_k127_4766533_1 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.0 1063.0
CMS2_k127_4766533_2 Pfam Transposase IS66 - - - 5.576e-217 676.0
CMS2_k127_4766533_3 S1 domain K00243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 557.0
CMS2_k127_4766533_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 464.0
CMS2_k127_4766533_5 FMN_bind - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 284.0
CMS2_k127_4766533_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001597 244.0
CMS2_k127_4766533_8 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000000000000000000001076 185.0
CMS2_k127_4919662_0 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 533.0
CMS2_k127_4919662_1 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 295.0
CMS2_k127_4919662_2 Protein of unknown function (DUF1456) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 289.0
CMS2_k127_4919662_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 283.0
CMS2_k127_4919662_5 Tellurite resistance protein TehB - - - 0.000000000000000000000000001494 112.0
CMS2_k127_4967982_0 Co Zn Cd efflux system component K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 549.0
CMS2_k127_4967982_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 348.0
CMS2_k127_4967982_2 - - - - 0.00000000000000000000000000000000000000000000000000000001931 198.0
CMS2_k127_49946_0 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 609.0
CMS2_k127_49946_1 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 569.0
CMS2_k127_49946_2 Belongs to the ClpA ClpB family K03694,K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 346.0
CMS2_k127_49946_3 Transglutaminase-like superfamily K07184 - - 0.000000000000000000000000000000000000000000000006569 173.0
CMS2_k127_49946_4 Protein of unknown function DUF58 - - - 0.000000000000000001981 96.0
CMS2_k127_5007023_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1156.0
CMS2_k127_5007023_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 4.801e-216 671.0
CMS2_k127_5007023_2 Heterodisulfide reductase subunit B K00241 - - 1.888e-196 612.0
CMS2_k127_5007023_4 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.000000000000000000000000000000001618 130.0
CMS2_k127_5007023_5 COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit - - - 0.00000000000000002099 81.0
CMS2_k127_5037821_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1249.0
CMS2_k127_5100585_0 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 492.0
CMS2_k127_5100585_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 300.0
CMS2_k127_5100585_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000003132 229.0
CMS2_k127_5100585_3 Paraquat-inducible protein A - - - 0.00000000000000000000000000000000000001221 146.0
CMS2_k127_5100982_0 Predicted permease K07089 - - 1.774e-194 610.0
CMS2_k127_5100982_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 471.0
CMS2_k127_5100982_2 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000001497 237.0
CMS2_k127_5100982_3 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.000000000000000000000000000000000000000000000000454 176.0
CMS2_k127_5100982_4 Transcriptional regulator K03892 - - 0.00000000000000000000000000000000000000001157 162.0
CMS2_k127_5100982_5 - - - - 0.000000000000002393 78.0
CMS2_k127_5105642_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1028.0
CMS2_k127_5105642_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0 1024.0
CMS2_k127_5105642_2 Histidine kinase - - - 3.643e-317 975.0
CMS2_k127_5105642_3 outer membrane porin, OprD family - - - 4.926e-231 722.0
CMS2_k127_5105642_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 422.0
CMS2_k127_5105642_5 dna polymerase iii K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 363.0
CMS2_k127_5105642_6 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 355.0
CMS2_k127_5105642_7 membrane - - - 0.000000000000000000000000000000000000000000000000000000002762 200.0
CMS2_k127_5105642_8 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000007373 139.0
CMS2_k127_5125654_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000003297 183.0
CMS2_k127_5125654_1 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000009379 169.0
CMS2_k127_5127357_0 Serine aminopeptidase, S33 K15756 - 3.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 546.0
CMS2_k127_5127357_1 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 501.0
CMS2_k127_5127357_2 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 287.0
CMS2_k127_5127357_3 - K17226 - - 0.00000000000000000000000000000000004057 140.0
CMS2_k127_5127357_4 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000004259 116.0
CMS2_k127_5127357_5 MTH538 TIR-like domain (DUF1863) K12132 - 2.7.11.1 0.0000000000000000000000000039 128.0
CMS2_k127_5127357_6 - - - - 0.000000000003848 73.0
CMS2_k127_5127357_7 determination of stomach left/right asymmetry - - - 0.000008132 59.0
CMS2_k127_5135304_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1861.0
CMS2_k127_5135304_1 Oxygen tolerance - - - 3.867e-276 854.0
CMS2_k127_5135304_10 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 295.0
CMS2_k127_5135304_11 Tetratricopeptide repeat K07114 - - 0.0000000000000000000000000000000000001581 153.0
CMS2_k127_5135304_2 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 1.075e-194 608.0
CMS2_k127_5135304_3 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 595.0
CMS2_k127_5135304_4 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 580.0
CMS2_k127_5135304_5 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 559.0
CMS2_k127_5135304_6 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 539.0
CMS2_k127_5135304_7 prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 531.0
CMS2_k127_5135304_8 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 525.0
CMS2_k127_5135304_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 424.0
CMS2_k127_5152991_0 Belongs to the SEDS family K05837 - - 3.028e-232 720.0
CMS2_k127_5152991_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 463.0
CMS2_k127_5152991_2 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 307.0
CMS2_k127_5152991_4 Belongs to the 'phage' integrase family - - - 0.0006911 42.0
CMS2_k127_5164843_0 Uncharacterised conserved protein (DUF2156) K01163 - - 7.232e-206 641.0
CMS2_k127_5164843_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002163 256.0
CMS2_k127_5164843_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000003042 187.0
CMS2_k127_5166880_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 399.0
CMS2_k127_5166880_2 RNA pseudouridylate synthase K06175 - 5.4.99.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 316.0
CMS2_k127_5166880_3 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 289.0
CMS2_k127_5166880_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 288.0
CMS2_k127_5166880_5 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 279.0
CMS2_k127_5166880_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000002361 132.0
CMS2_k127_5172537_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1978.0
CMS2_k127_5172537_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 3.303e-209 651.0
CMS2_k127_5172537_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 509.0
CMS2_k127_5172537_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 466.0
CMS2_k127_5172537_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 405.0
CMS2_k127_5177202_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.22e-226 700.0
CMS2_k127_5177202_1 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 2.803e-203 634.0
CMS2_k127_5177202_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 357.0
CMS2_k127_5178674_0 Belongs to the 5'-nucleotidase family K01119,K17224 - 3.1.3.6,3.1.4.16 0.0 1215.0
CMS2_k127_5178674_1 Receptor - - - 2.351e-271 840.0
CMS2_k127_5178674_2 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 470.0
CMS2_k127_5178674_3 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 362.0
CMS2_k127_5178674_4 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 287.0
CMS2_k127_5178674_5 oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000000000000000000000000000000003461 215.0
CMS2_k127_5178674_6 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000000000000000000000009266 205.0
CMS2_k127_5178674_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000001351 86.0
CMS2_k127_5192422_0 Two-component sensor histidine kinase response regulator - - - 6.28e-197 650.0
CMS2_k127_5192422_1 - - - - 0.0000000002409 65.0
CMS2_k127_5196662_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1147.0
CMS2_k127_5196662_1 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 557.0
CMS2_k127_5196662_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 317.0
CMS2_k127_5196662_3 - - - - 0.0000000000000000000000000000000000000000009954 156.0
CMS2_k127_5196662_5 Enoyl-(Acyl carrier protein) reductase K16216 - 1.1.1.320 0.000000000000000005013 83.0
CMS2_k127_5199360_0 COG2951 Membrane-bound lytic murein transglycosylase B K08305 - - 2.167e-195 611.0
CMS2_k127_5199360_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 563.0
CMS2_k127_5199360_2 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 534.0
CMS2_k127_5199360_3 Belongs to the RNase T2 family K01166 - 3.1.27.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 500.0
CMS2_k127_5199360_4 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 286.0
CMS2_k127_5199360_5 Protein required for attachment to host cells - - - 0.00000000000000000000000000000000000000000001627 166.0
CMS2_k127_5207436_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.786e-214 667.0
CMS2_k127_5207436_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000003488 235.0
CMS2_k127_5207436_2 - - - - 0.00000000009848 61.0
CMS2_k127_5207436_3 Imidazolonepropionase and related - - - 0.0000368 49.0
CMS2_k127_5207436_4 - - - - 0.0002416 44.0
CMS2_k127_5212131_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.311e-291 896.0
CMS2_k127_5212131_1 Involved in the TonB-independent uptake of proteins K03641 - - 4.671e-253 782.0
CMS2_k127_5212131_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 515.0
CMS2_k127_5212131_11 Cell division protein K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 482.0
CMS2_k127_5212131_12 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 452.0
CMS2_k127_5212131_13 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 442.0
CMS2_k127_5212131_14 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 406.0
CMS2_k127_5212131_15 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 373.0
CMS2_k127_5212131_16 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 368.0
CMS2_k127_5212131_17 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 325.0
CMS2_k127_5212131_18 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 321.0
CMS2_k127_5212131_19 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 319.0
CMS2_k127_5212131_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 5.461e-249 769.0
CMS2_k127_5212131_20 MotA TolQ ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 318.0
CMS2_k127_5212131_21 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 307.0
CMS2_k127_5212131_22 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K18284 - 3.2.2.30,3.2.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 310.0
CMS2_k127_5212131_23 Fibronectin type 3 domain-containing protein K06882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006616 243.0
CMS2_k127_5212131_24 transport protein K03559 - - 0.000000000000000000000000000000000000000000000000000000000000000000003232 235.0
CMS2_k127_5212131_25 ATP-binding protein K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000003108 235.0
CMS2_k127_5212131_26 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000000000000000008685 226.0
CMS2_k127_5212131_27 sh3 domain protein K02450 - - 0.00000000000000000000000000000000000000000000000000000000000001894 215.0
CMS2_k127_5212131_28 COG1773 Rubredoxin - - - 0.00000000000000000000000000009666 115.0
CMS2_k127_5212131_29 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000002859 51.0
CMS2_k127_5212131_3 COG0739 Membrane proteins related to metalloendopeptidases - - - 2.715e-234 730.0
CMS2_k127_5212131_4 Response regulator, receiver K07719 - - 4.006e-233 726.0
CMS2_k127_5212131_5 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 9.555e-230 715.0
CMS2_k127_5212131_6 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 595.0
CMS2_k127_5212131_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 587.0
CMS2_k127_5212131_8 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 580.0
CMS2_k127_5212131_9 Belongs to the TtcA family K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 538.0
CMS2_k127_5214307_0 Protein of unknown function (DUF1538) - - - 3.927e-293 903.0
CMS2_k127_5214307_1 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 6.677e-205 643.0
CMS2_k127_5214307_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 435.0
CMS2_k127_5214307_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000007252 231.0
CMS2_k127_5214307_4 Belongs to the P(II) protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000004679 223.0
CMS2_k127_5214307_5 Chorismate mutase K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000000000000007537 186.0
CMS2_k127_5238838_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.716e-297 913.0
CMS2_k127_5238838_1 Glycosyl transferase family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 557.0
CMS2_k127_5238838_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 388.0
CMS2_k127_5238838_3 molybdopterin converting factor K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 281.0
CMS2_k127_5238838_4 molybdopterin converting factor K03636 - - 0.0000000000000000000000000000000000001133 143.0
CMS2_k127_5238838_5 photosystem II stabilization K02237 - - 0.00000000000000000000000000000001402 128.0
CMS2_k127_5238838_6 Oligosaccharide transferase K07151 - 2.4.99.18 0.0000000000000000000000000008547 112.0
CMS2_k127_5247120_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 3.24e-198 617.0
CMS2_k127_5247120_2 NAD-dependent protein deacetylase, SIR2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 396.0
CMS2_k127_5247120_3 transformation system protein K02242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 346.0
CMS2_k127_5247120_4 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 316.0
CMS2_k127_5247120_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 306.0
CMS2_k127_5247120_6 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001977 259.0
CMS2_k127_5247120_7 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000000000001045 192.0
CMS2_k127_5252020_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 5.637e-306 942.0
CMS2_k127_5252020_1 mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 600.0
CMS2_k127_5252020_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 444.0
CMS2_k127_5252020_3 Predicted periplasmic protein (DUF2092) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 290.0
CMS2_k127_5252020_4 fumarate reductase, iron-sulfur protein K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000003692 254.0
CMS2_k127_5252020_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000003394 184.0
CMS2_k127_5252020_6 - - - - 0.000000000000000000000000000000000000000000000000001537 189.0
CMS2_k127_5252020_7 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.0002496 43.0
CMS2_k127_5277108_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 1.782e-247 769.0
CMS2_k127_5277108_1 Histidine kinase K07676,K10715,K20976 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 1.953e-230 722.0
CMS2_k127_5277108_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 286.0
CMS2_k127_5277108_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003072 242.0
CMS2_k127_5285928_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 542.0
CMS2_k127_5285928_1 ATP-dependent CLP protease ATP-binding subunit K03694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 469.0
CMS2_k127_5285928_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 368.0
CMS2_k127_5285928_3 component I K01665 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 290.0
CMS2_k127_5285928_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000000000000008653 189.0
CMS2_k127_5330713_0 Cation transporter/ATPase, N-terminus K01539 - 3.6.3.9 5.446e-306 962.0
CMS2_k127_5330713_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.145e-299 920.0
CMS2_k127_5330713_10 ATPase or kinase K06925 - - 0.000000000000000000003371 92.0
CMS2_k127_5330713_2 potassium channel protein K10716 - - 2.763e-258 799.0
CMS2_k127_5330713_3 ABC transporter, ATP-binding protein K01990,K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 467.0
CMS2_k127_5330713_4 tigr02757 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 458.0
CMS2_k127_5330713_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 414.0
CMS2_k127_5330713_6 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 396.0
CMS2_k127_5330713_7 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 306.0
CMS2_k127_5351560_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 3.116e-239 739.0
CMS2_k127_5351560_1 Aminotransferase K00812 - 2.6.1.1 3.743e-237 736.0
CMS2_k127_5351560_2 arginine decarboxylase K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 564.0
CMS2_k127_5351560_3 PFAM Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 543.0
CMS2_k127_5351560_4 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 450.0
CMS2_k127_5351560_5 membrane-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 340.0
CMS2_k127_5354268_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 563.0
CMS2_k127_5354268_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 490.0
CMS2_k127_5354268_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 332.0
CMS2_k127_5354268_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003152 247.0
CMS2_k127_5354268_5 PFAM Thioredoxin K03671 - - 0.000000000000000000000000000000000000000000000000000000000000000000002543 235.0
CMS2_k127_5354268_6 peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000003335 229.0
CMS2_k127_5354268_7 - - - - 0.000000000000000005425 85.0
CMS2_k127_5354268_8 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000004662 65.0
CMS2_k127_5356061_0 Putative diguanylate phosphodiesterase - - - 0.0 1103.0
CMS2_k127_5356061_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 6.47e-322 988.0
CMS2_k127_5356061_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 1.398e-237 738.0
CMS2_k127_5356061_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008538 466.0
CMS2_k127_5356061_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000001465 174.0
CMS2_k127_5356061_5 Encoded by K10408 - - 0.00001661 47.0
CMS2_k127_5374807_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide - - - 1.605e-310 959.0
CMS2_k127_5374807_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.5.1 2.817e-263 812.0
CMS2_k127_5374807_2 Ni Fe-hydrogenase, b-type cytochrome subunit K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 370.0
CMS2_k127_5374807_3 PFAM peptidase M52 hydrogen uptake protein K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000001602 237.0
CMS2_k127_5374807_4 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000002735 203.0
CMS2_k127_5432085_0 DNA polymerase K02337 - 2.7.7.7 0.0 1060.0
CMS2_k127_5432085_1 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 400.0
CMS2_k127_5432085_2 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 376.0
CMS2_k127_5432085_4 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000002636 216.0
CMS2_k127_5457699_0 NAD-dependent protein deacetylase, SIR2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 511.0
CMS2_k127_5457699_1 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 303.0
CMS2_k127_5457699_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002439 234.0
CMS2_k127_5457699_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000002986 50.0
CMS2_k127_5471153_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 2.256e-250 773.0
CMS2_k127_5471153_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000009539 219.0
CMS2_k127_5476344_0 sulfur dehydrogenase subunit K17225 - - 2.089e-302 927.0
CMS2_k127_5476344_1 - K17226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004651 255.0
CMS2_k127_5476344_2 ADP-ribosylglycohydrolase - - - 0.00000000000000000001475 91.0
CMS2_k127_5476344_3 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000008603 80.0
CMS2_k127_5482868_0 FAD dependent oxidoreductase - - - 7.976e-235 728.0
CMS2_k127_5482868_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 428.0
CMS2_k127_5482868_2 - - - - 0.00000000000000000000000000000000000003746 150.0
CMS2_k127_5484960_0 Belongs to the RtcB family K14415 - 6.5.1.3 2.752e-297 914.0
CMS2_k127_5484960_2 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000296 268.0
CMS2_k127_5484960_3 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.000000000000000000000000000000000000000002373 155.0
CMS2_k127_5484960_4 Glyoxalase-like domain K06996 - - 0.000000000002675 70.0
CMS2_k127_5484960_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000008603 53.0
CMS2_k127_5530951_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 2241.0
CMS2_k127_5530951_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 3.578e-297 915.0
CMS2_k127_5530951_10 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 407.0
CMS2_k127_5530951_11 COG1881 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 371.0
CMS2_k127_5530951_12 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 324.0
CMS2_k127_5530951_13 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 303.0
CMS2_k127_5530951_14 Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003332 275.0
CMS2_k127_5530951_15 Putative ATP-dependant zinc protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004059 267.0
CMS2_k127_5530951_16 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000009187 225.0
CMS2_k127_5530951_17 DnaK suppressor protein K06204 - - 0.000000000000000000000000000000000000000000000000000000000000002395 218.0
CMS2_k127_5530951_18 MerR HTH family regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000515 211.0
CMS2_k127_5530951_19 membrane transporter protein K07090 - - 0.0000000000000000000000000000001363 124.0
CMS2_k127_5530951_2 M42 glutamyl aminopeptidase - - - 2.985e-225 700.0
CMS2_k127_5530951_20 protein involved in tolerance to divalent cations K03926 - - 0.00000000000000000004719 93.0
CMS2_k127_5530951_21 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000003664 64.0
CMS2_k127_5530951_3 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 6.726e-206 642.0
CMS2_k127_5530951_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 8.076e-204 635.0
CMS2_k127_5530951_5 Belongs to the RimK family K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 574.0
CMS2_k127_5530951_6 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 511.0
CMS2_k127_5530951_7 CorA-like Mg2 transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 467.0
CMS2_k127_5530951_8 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 466.0
CMS2_k127_5530951_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 422.0
CMS2_k127_5578883_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 9.964e-273 840.0
CMS2_k127_5578883_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000004158 143.0
CMS2_k127_5625294_0 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002684 270.0
CMS2_k127_5625294_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000002838 197.0
CMS2_k127_5625294_2 COG4232 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000582 193.0
CMS2_k127_5625294_3 COG1252 NADH dehydrogenase FAD-containing subunit K03885 - 1.6.99.3 0.0001764 46.0
CMS2_k127_5639600_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1703.0
CMS2_k127_5639600_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 566.0
CMS2_k127_5639600_2 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000706 229.0
CMS2_k127_5639600_3 - - - - 0.0000000000000000000000000000000000000000000000000000002 203.0
CMS2_k127_5639600_4 Protein of unknown function (DUF1444) - - - 0.000000000000000000000000000000000000000000000005234 182.0
CMS2_k127_5639600_5 - - - - 0.0000000000000000000000000000004886 129.0
CMS2_k127_5639600_6 Psort location Cytoplasmic, score - - - 0.000000000000000006553 93.0
CMS2_k127_5639600_7 Outer membrane efflux protein - - - 0.000000035 65.0
CMS2_k127_5661355_0 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 303.0
CMS2_k127_5661355_1 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 260.0
CMS2_k127_5661355_2 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000006698 204.0
CMS2_k127_5661355_3 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000001143 203.0
CMS2_k127_5676023_0 Glycerol-3-phosphate dehydrogenase K11473 - - 2.447e-289 888.0
CMS2_k127_5676023_1 Histidine kinase K02484 - 2.7.13.3 3.719e-248 768.0
CMS2_k127_5676023_2 PFAM response regulator receiver K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 407.0
CMS2_k127_5676023_3 acid membrane antigen A - - - 0.00000000000002274 72.0
CMS2_k127_5831192_0 Abc transporter K06158 - - 0.0 1157.0
CMS2_k127_5831192_1 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009488 308.0
CMS2_k127_5831192_2 CYTH K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001901 273.0
CMS2_k127_5831192_3 - - - - 0.00000000000000000000000000000001591 128.0
CMS2_k127_5831192_4 - - - - 0.00000000000000000000000000001539 118.0
CMS2_k127_5831192_6 Hit family K02503 - - 0.000000000000000000000005894 100.0
CMS2_k127_5831240_0 Flavocytochrome c sulphide dehydrogenase, flavin-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 525.0
CMS2_k127_5831240_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000001109 132.0
CMS2_k127_5831240_2 - - - - 0.00000000000000005958 85.0
CMS2_k127_5832471_0 Histidine kinase K02030 - - 0.0 1120.0
CMS2_k127_5832471_1 penicillin-binding protein K05515 - 3.4.16.4 0.0 1062.0
CMS2_k127_5832471_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 469.0
CMS2_k127_5832471_3 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 402.0
CMS2_k127_5832471_4 Imidazoleglycerol-phosphate dehydratase K01089,K01693 - 3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 386.0
CMS2_k127_5832471_5 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 312.0
CMS2_k127_5832471_6 acetyltransferase K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 301.0
CMS2_k127_5832471_7 lipopolysaccharide binding K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001771 266.0
CMS2_k127_5832471_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004357 259.0
CMS2_k127_5832471_9 lytic murein transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000007428 166.0
CMS2_k127_5929341_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 6.232e-252 781.0
CMS2_k127_5929341_1 Sodium:sulfate symporter transmembrane region - - - 3.584e-246 774.0
CMS2_k127_5929341_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 420.0
CMS2_k127_5929341_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 387.0
CMS2_k127_5929341_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 346.0
CMS2_k127_5929341_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 338.0
CMS2_k127_5929341_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002816 252.0
CMS2_k127_5929341_7 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000001126 188.0
CMS2_k127_5929341_8 - - - - 0.00000007661 55.0
CMS2_k127_5929341_9 - - - - 0.000001867 51.0
CMS2_k127_6110483_0 Belongs to the UbiD family K03182 - 4.1.1.98 6.634e-308 944.0
CMS2_k127_6110483_1 zinc metalloprotease K11749 - - 2.928e-201 629.0
CMS2_k127_6110483_2 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 565.0
CMS2_k127_6110483_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 426.0
CMS2_k127_6110483_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 420.0
CMS2_k127_6110483_5 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 374.0
CMS2_k127_6110483_6 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 364.0
CMS2_k127_6110483_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 304.0
CMS2_k127_6110483_8 Belongs to the Fur family K09825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001066 267.0
CMS2_k127_6117645_0 TonB dependent receptor K16092 - - 1.224e-294 914.0
CMS2_k127_6117645_1 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 372.0
CMS2_k127_6117645_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005219 273.0
CMS2_k127_6117645_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000001163 144.0
CMS2_k127_6139737_0 4 iron, 4 sulfur cluster binding - - - 4.787e-309 948.0
CMS2_k127_6139737_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 464.0
CMS2_k127_6151624_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1505.0
CMS2_k127_6151624_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1323.0
CMS2_k127_6151624_2 (EAL) domain protein - - - 6.656e-278 858.0
CMS2_k127_6151624_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 1.221e-208 649.0
CMS2_k127_6151624_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000005408 258.0
CMS2_k127_6151624_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002583 224.0
CMS2_k127_6151624_6 Protein of unknown function (DUF2853) - - - 0.0000000000000000000000000000000000000000000000000000000006093 202.0
CMS2_k127_6151624_7 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000338 146.0
CMS2_k127_6172565_0 Domain of unknown function DUF87 - - - 0.0 1369.0
CMS2_k127_6172565_1 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 411.0
CMS2_k127_6172565_2 Methyltransferase domain K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 410.0
CMS2_k127_6172565_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 395.0
CMS2_k127_6172565_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 340.0
CMS2_k127_6172565_5 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 334.0
CMS2_k127_6172565_6 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000000000000000000000000000000000000003647 185.0
CMS2_k127_6172565_7 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.00000000000000000000000000000000000000001585 153.0
CMS2_k127_6172565_8 thiamine-phosphate diphosphorylase activity K00788 - 2.5.1.3 0.00000000000000000000000000000000001982 139.0
CMS2_k127_6176945_0 Protein of unknown function (DUF2867) - - - 9.14e-269 831.0
CMS2_k127_6176945_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 606.0
CMS2_k127_6176945_2 Epimerase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 503.0
CMS2_k127_6176945_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 423.0
CMS2_k127_6176945_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 332.0
CMS2_k127_6176945_5 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 320.0
CMS2_k127_6176945_6 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 315.0
CMS2_k127_6177898_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 1.342e-236 736.0
CMS2_k127_6177898_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 1.218e-198 622.0
CMS2_k127_6177898_2 Protein of unknown function (DUF819) - - - 1.395e-196 618.0
CMS2_k127_6177898_3 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 485.0
CMS2_k127_6177898_4 Abc transporter K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 464.0
CMS2_k127_6177898_5 periplasmic solute binding protein K02077,K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 413.0
CMS2_k127_6177898_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 303.0
CMS2_k127_6202508_0 Histidine kinase K07648,K07679 - 2.7.13.3 0.0 1223.0
CMS2_k127_6202508_1 Glycosyl hydrolase family 3 K01207 - 3.2.1.52 9.108e-218 678.0
CMS2_k127_6202508_10 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003607 239.0
CMS2_k127_6202508_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000000000000000000000000000000000005085 231.0
CMS2_k127_6202508_12 DNA processing protein K04096 - - 0.00000000000000000004056 89.0
CMS2_k127_6202508_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 2.326e-213 664.0
CMS2_k127_6202508_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 581.0
CMS2_k127_6202508_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 458.0
CMS2_k127_6202508_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 444.0
CMS2_k127_6202508_6 NlpC/P60 family K13694,K13695 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 404.0
CMS2_k127_6202508_7 NlpC/P60 family K13694,K13695 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 372.0
CMS2_k127_6202508_8 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 322.0
CMS2_k127_6202508_9 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 304.0
CMS2_k127_6205091_0 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 0.0 1257.0
CMS2_k127_6205091_1 Belongs to the SEDS family K03588 - - 1.817e-195 611.0
CMS2_k127_6205091_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 376.0
CMS2_k127_6205330_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 7.972e-302 926.0
CMS2_k127_6205330_1 Belongs to the aldehyde dehydrogenase family - - - 1.754e-287 885.0
CMS2_k127_6205330_2 dehydrogenase K08325 - - 3.849e-232 721.0
CMS2_k127_6205330_3 COG0530 Ca2 Na antiporter K07301 - - 1.222e-194 610.0
CMS2_k127_6205330_4 Phospholipase/Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 382.0
CMS2_k127_6205330_5 PFAM SEC-C motif domain protein K09858 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 300.0
CMS2_k127_6205330_6 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 290.0
CMS2_k127_6205330_7 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 282.0
CMS2_k127_6205330_8 Haem-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004547 222.0
CMS2_k127_6205330_9 Leucine Rich repeats (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000009928 203.0
CMS2_k127_6208691_0 Sulfatase - - - 0.0 1170.0
CMS2_k127_6208691_1 domain, Protein - - - 2.443e-259 809.0
CMS2_k127_6208691_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000002235 126.0
CMS2_k127_6217747_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1547.0
CMS2_k127_6217747_1 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 0.0 1116.0
CMS2_k127_6217747_10 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 422.0
CMS2_k127_6217747_11 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 346.0
CMS2_k127_6217747_12 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 323.0
CMS2_k127_6217747_13 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 316.0
CMS2_k127_6217747_14 Epimerase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 305.0
CMS2_k127_6217747_15 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 284.0
CMS2_k127_6217747_16 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 280.0
CMS2_k127_6217747_17 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003822 268.0
CMS2_k127_6217747_18 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000000000000000000000000000000000000008798 192.0
CMS2_k127_6217747_19 - - - - 0.000000000000000000000000000000000000000004176 154.0
CMS2_k127_6217747_2 Acts as a magnesium transporter K06213 - - 2.006e-265 821.0
CMS2_k127_6217747_21 AAA domain K04770 - - 0.0000001034 55.0
CMS2_k127_6217747_22 - - - - 0.0002223 43.0
CMS2_k127_6217747_3 NfeD-like C-terminal, partner-binding - - - 5.162e-226 705.0
CMS2_k127_6217747_4 Sodium calcium exchanger membrane K07300 - - 8.952e-214 667.0
CMS2_k127_6217747_5 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 556.0
CMS2_k127_6217747_6 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 503.0
CMS2_k127_6217747_7 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 466.0
CMS2_k127_6217747_8 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 455.0
CMS2_k127_6217747_9 Membrane protease subunits - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 445.0
CMS2_k127_6219495_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 321.0
CMS2_k127_6219495_1 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000003716 229.0
CMS2_k127_6219495_2 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000006305 181.0
CMS2_k127_6219495_3 Cytochrome oxidase maturation protein - - - 0.0000000000000000000000000000000000001585 141.0
CMS2_k127_6219861_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 7.473e-245 758.0
CMS2_k127_6219861_1 cAMP phosphodiesterases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009498 270.0
CMS2_k127_6219861_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001009 233.0
CMS2_k127_6219861_3 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000008662 59.0
CMS2_k127_6229509_0 ATPase (AAA K07133 - - 1.583e-220 685.0
CMS2_k127_6229509_1 ribosomal protein L3 K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 369.0
CMS2_k127_6229509_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000000002151 203.0
CMS2_k127_6229509_3 - - - - 0.0000000000000000000005189 98.0
CMS2_k127_6229509_4 - - - - 0.00004611 49.0
CMS2_k127_6245441_0 Outer membrane efflux protein - - - 4.193e-223 696.0
CMS2_k127_6245441_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.202e-219 687.0
CMS2_k127_6245441_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 392.0
CMS2_k127_6245441_3 Bacterial regulatory proteins, tetR family K03577 - - 0.00000000000000000000000000000000004996 139.0
CMS2_k127_6253708_0 MMPL family K07003 - - 0.0 1311.0
CMS2_k127_6253708_1 (Lipo)protein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 365.0
CMS2_k127_6253708_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 350.0
CMS2_k127_6253708_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 348.0
CMS2_k127_6253708_4 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001229 263.0
CMS2_k127_6253708_5 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001447 258.0
CMS2_k127_6253708_6 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0000000000000000000000000000000000000000002126 160.0
CMS2_k127_6259024_0 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000001374 189.0
CMS2_k127_6259024_3 Rhodanese Homology Domain - - - 0.00000000000000000000000004027 111.0
CMS2_k127_6259024_4 Thioredoxin K03672 - 1.8.1.8 0.00000000000001533 76.0
CMS2_k127_6281155_0 peptidylprolyl isomerase K03770 - 5.2.1.8 8.534e-291 895.0
CMS2_k127_6281155_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 8.161e-282 869.0
CMS2_k127_6281155_2 Glutathionylspermidine synthase - - - 1.099e-239 742.0
CMS2_k127_6281155_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 7.357e-224 696.0
CMS2_k127_6281155_4 Response regulator, receiver K07719 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 446.0
CMS2_k127_6281155_5 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 391.0
CMS2_k127_6281155_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 361.0
CMS2_k127_6281155_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 352.0
CMS2_k127_6281155_8 PFAM glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000006015 218.0
CMS2_k127_6325370_0 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains K02584 - - 1.15e-252 793.0
CMS2_k127_6325370_1 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 5.421e-220 696.0
CMS2_k127_6325370_10 ABC transporter permease K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 370.0
CMS2_k127_6325370_11 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 319.0
CMS2_k127_6325370_12 TIGRFAM SagB-type dehydrogenase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000129 292.0
CMS2_k127_6325370_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008234 281.0
CMS2_k127_6325370_14 AhpC/TSA family K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009161 275.0
CMS2_k127_6325370_15 Ferredoxin - - - 0.00000000000000000000000000000000000000000000004866 170.0
CMS2_k127_6325370_16 NifQ K15790 - - 0.00000000000000000000000000000000000003245 146.0
CMS2_k127_6325370_17 Belongs to the ArsC family - - - 0.00000000000000000000000000000000002447 139.0
CMS2_k127_6325370_18 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000464 136.0
CMS2_k127_6325370_19 TOBE domain - - - 0.0000000000000000000000000000000001297 136.0
CMS2_k127_6325370_2 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 4.84e-214 670.0
CMS2_k127_6325370_21 Ferredoxin - - - 0.000000000000000000000000000001192 123.0
CMS2_k127_6325370_22 - - - - 0.0000000000000000000000004623 108.0
CMS2_k127_6325370_23 nitrogen fixation protein FixT K02593 - - 0.000000000000000000000589 96.0
CMS2_k127_6325370_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.299e-194 614.0
CMS2_k127_6325370_4 COG0714 MoxR-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 538.0
CMS2_k127_6325370_5 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 516.0
CMS2_k127_6325370_6 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 501.0
CMS2_k127_6325370_7 Putative metallopeptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 485.0
CMS2_k127_6325370_8 alanine dehydrogenase K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 454.0
CMS2_k127_6325370_9 ATP-binding protein K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 436.0
CMS2_k127_6379686_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 4.2.3.5 2.621e-215 670.0
CMS2_k127_6379686_1 tetratricopeptide repeat - - - 2.284e-208 651.0
CMS2_k127_6379686_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 478.0
CMS2_k127_6379686_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 428.0
CMS2_k127_6415067_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0 2285.0
CMS2_k127_6415067_1 acetolactate synthase K01652 - 2.2.1.6 0.0 1122.0
CMS2_k127_6415067_2 Dipeptidase K01270 - - 5.745e-202 631.0
CMS2_k127_6415067_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 599.0
CMS2_k127_6415067_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 592.0
CMS2_k127_6415067_5 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 516.0
CMS2_k127_6415067_6 signal transduction sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 312.0
CMS2_k127_6415067_7 acetolactate synthase K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 312.0
CMS2_k127_6415067_8 - - - - 0.0000000000000000000000000000000000001437 141.0
CMS2_k127_6415067_9 Protein of unknown function (DUF1653) - - - 0.0000000000000000000000000000000000005975 141.0
CMS2_k127_6423139_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 6.385e-291 898.0
CMS2_k127_6423139_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.136e-272 840.0
CMS2_k127_6423139_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.378e-267 831.0
CMS2_k127_6423139_3 Metallophosphoesterase K07098 - - 1.226e-221 689.0
CMS2_k127_6423139_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 507.0
CMS2_k127_6423139_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 352.0
CMS2_k127_6423139_7 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.00000000000000000000000001006 115.0
CMS2_k127_6467056_0 Co-chaperone-curved DNA binding protein A K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 548.0
CMS2_k127_6467056_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 527.0
CMS2_k127_6467056_2 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 357.0
CMS2_k127_6467056_3 polysaccharide export K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 310.0
CMS2_k127_6467056_4 Rhodanese-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002864 247.0
CMS2_k127_6467056_5 Transcriptional regulator K13640 - - 0.000000000000000000000000000000000000000000000000000000000000000000002472 236.0
CMS2_k127_6489776_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 1186.0
CMS2_k127_6489776_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 3.556e-295 906.0
CMS2_k127_6489776_10 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001549 253.0
CMS2_k127_6489776_11 Domain of unknown function (DUF1882) - - - 0.000000000000000000000000000000000000000000000000000000000000000225 224.0
CMS2_k127_6489776_12 Hemolysin K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000009773 153.0
CMS2_k127_6489776_2 anthranilate synthase component K01657 - 4.1.3.27 2.259e-291 896.0
CMS2_k127_6489776_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 1.205e-273 843.0
CMS2_k127_6489776_4 Histidine kinase-like ATPases K02484 - 2.7.13.3 1.491e-237 736.0
CMS2_k127_6489776_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 507.0
CMS2_k127_6489776_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 491.0
CMS2_k127_6489776_7 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 447.0
CMS2_k127_6489776_8 response regulator K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 428.0
CMS2_k127_6489776_9 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03591 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 405.0
CMS2_k127_6522917_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1285.0
CMS2_k127_6522917_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1218.0
CMS2_k127_6522917_10 DnaJ domain - - - 0.0000000001188 66.0
CMS2_k127_6522917_2 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1049.0
CMS2_k127_6522917_3 Belongs to the GARS family K01945 - 6.3.4.13 6.492e-273 840.0
CMS2_k127_6522917_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 564.0
CMS2_k127_6522917_5 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 408.0
CMS2_k127_6522917_7 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 348.0
CMS2_k127_6522917_9 RDD family - - - 0.00000000000005248 78.0
CMS2_k127_6552425_0 ATP-dependent CLP protease ATP-binding subunit K03694 - - 2e-323 992.0
CMS2_k127_6552425_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 2.452e-201 630.0
CMS2_k127_6552425_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 407.0
CMS2_k127_6552425_3 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 404.0
CMS2_k127_655265_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1943.0
CMS2_k127_655265_1 UPF0313 protein - - - 0.0 1164.0
CMS2_k127_655265_10 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 2.347e-213 664.0
CMS2_k127_655265_11 Cytochrome K00428 - 1.11.1.5 6.62e-211 656.0
CMS2_k127_655265_12 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.11e-207 650.0
CMS2_k127_655265_13 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 1.851e-200 627.0
CMS2_k127_655265_14 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 524.0
CMS2_k127_655265_15 of the HAD superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 518.0
CMS2_k127_655265_16 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 438.0
CMS2_k127_655265_17 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 430.0
CMS2_k127_655265_18 Acetyl xylan esterase (AXE1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 413.0
CMS2_k127_655265_19 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 419.0
CMS2_k127_655265_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1082.0
CMS2_k127_655265_20 COGs COG3786 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 346.0
CMS2_k127_655265_21 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 334.0
CMS2_k127_655265_22 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 306.0
CMS2_k127_655265_23 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 306.0
CMS2_k127_655265_24 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 296.0
CMS2_k127_655265_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 287.0
CMS2_k127_655265_26 L-threonylcarbamoyladenylate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002373 272.0
CMS2_k127_655265_27 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001064 256.0
CMS2_k127_655265_28 (HIT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001562 236.0
CMS2_k127_655265_29 Belongs to the glucose-6-phosphate 1-epimerase family K01792 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 5.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000006476 237.0
CMS2_k127_655265_3 phosphate transporter K03306 - - 1.145e-304 938.0
CMS2_k127_655265_30 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000002666 182.0
CMS2_k127_655265_31 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000000000000000000000000000001767 143.0
CMS2_k127_655265_32 Rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000008576 131.0
CMS2_k127_655265_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 4.089e-293 903.0
CMS2_k127_655265_5 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 1.329e-274 846.0
CMS2_k127_655265_6 Na H antiporter - - - 2.987e-263 816.0
CMS2_k127_655265_7 COG0436 Aspartate tyrosine aromatic aminotransferase K10907 - - 4.574e-233 722.0
CMS2_k127_655265_8 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 4.486e-227 704.0
CMS2_k127_655265_9 rod shape-determining protein mreB K03569 - - 5.7e-215 668.0
CMS2_k127_6564430_0 protein conserved in bacteria K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 434.0
CMS2_k127_6564430_1 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 336.0
CMS2_k127_6564430_2 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001779 254.0
CMS2_k127_6564430_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000001481 206.0
CMS2_k127_6564430_4 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000007848 189.0
CMS2_k127_6573639_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 5.513e-212 659.0
CMS2_k127_6573639_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 400.0
CMS2_k127_6573639_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000001767 236.0
CMS2_k127_6573639_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000000004552 223.0
CMS2_k127_6606633_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1238.0
CMS2_k127_6606633_1 dihydropteroate synthase K00796 - 2.5.1.15 1.591e-218 681.0
CMS2_k127_6606633_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 401.0
CMS2_k127_6606633_3 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 354.0
CMS2_k127_6606633_4 DNA replication regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 350.0
CMS2_k127_6606633_5 Hemolysin K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 341.0
CMS2_k127_6606633_6 DUF218 domain K03748 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0042221,GO:0042493,GO:0044425,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 340.0
CMS2_k127_6629818_0 COG0474 Cation transport ATPase - - - 0.0 1564.0
CMS2_k127_6629818_1 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002303 265.0
CMS2_k127_6629818_2 Zeta toxin - - - 0.00000000000000000004897 98.0
CMS2_k127_6705821_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0 1110.0
CMS2_k127_6705821_1 Uncharacterised MFS-type transporter YbfB - - - 1.772e-224 699.0
CMS2_k127_6705821_2 Radical SAM K04069 - 1.97.1.4 1.122e-221 687.0
CMS2_k127_6705821_3 Glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 563.0
CMS2_k127_6705821_4 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 424.0
CMS2_k127_6705821_5 Belongs to the MEMO1 family K06990 - - 0.00000000000008456 72.0
CMS2_k127_6786950_0 GTP-binding protein K06207 - - 0.0 1014.0
CMS2_k127_6786950_1 PFAM HI0933 family protein K07007 - - 1.322e-232 722.0
CMS2_k127_6786950_2 Thiamine-binding protein - - - 0.000000000000000007674 83.0
CMS2_k127_6863078_0 COG4775 Outer membrane protein protective antigen OMA87 K07278 - - 1.103e-279 870.0
CMS2_k127_6863078_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 548.0
CMS2_k127_6863078_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 328.0
CMS2_k127_6876302_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 2.181e-275 848.0
CMS2_k127_6876302_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 353.0
CMS2_k127_6876302_2 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002371 259.0
CMS2_k127_6876302_3 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000005499 244.0
CMS2_k127_6876302_4 ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000000000000004272 231.0
CMS2_k127_6876302_5 Nitrogen fixation protein NifU - - - 0.000000000000000000000000000000000000000000000000001821 182.0
CMS2_k127_6876302_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000008953 62.0
CMS2_k127_6884707_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 558.0
CMS2_k127_6884707_1 4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 494.0
CMS2_k127_6884707_2 uracil DNA glycosylase K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 390.0
CMS2_k127_6884707_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 351.0
CMS2_k127_6884707_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000007475 109.0
CMS2_k127_6886593_0 Peptidase, M16 - - - 2.898e-253 784.0
CMS2_k127_6886593_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 372.0
CMS2_k127_6886593_2 ATP-dependent DNA helicase K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000003988 250.0
CMS2_k127_6895332_0 Pfam Transposase IS66 - - - 3.151e-237 737.0
CMS2_k127_6895332_1 FMN_bind - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 312.0
CMS2_k127_6895332_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007128 250.0
CMS2_k127_6895332_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000009454 155.0
CMS2_k127_6913332_0 COG0474 Cation transport ATPase - - - 0.0 1480.0
CMS2_k127_6913332_1 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1473.0
CMS2_k127_6913332_2 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.0 1387.0
CMS2_k127_6913332_3 alanine dehydrogenase K00259 - 1.4.1.1 3.706e-210 657.0
CMS2_k127_6913332_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 520.0
CMS2_k127_6913332_5 hydrogenase (NiFe) small subunit HydA K05927 - 1.12.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 479.0
CMS2_k127_6913332_6 COG1734 DnaK suppressor protein K06204 - - 0.0000000000000000000000000000000000000000000000000000001226 195.0
CMS2_k127_6915379_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 569.0
CMS2_k127_6915379_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 506.0
CMS2_k127_6915379_2 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 464.0
CMS2_k127_6915379_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 420.0
CMS2_k127_6915379_4 Uncharacterized protein domain (DUF2202) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 406.0
CMS2_k127_6915379_5 Putative small multi-drug export protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 389.0
CMS2_k127_6915379_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000009019 117.0
CMS2_k127_6918292_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 565.0
CMS2_k127_6918292_1 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 334.0
CMS2_k127_6918292_2 COG2346 Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 317.0
CMS2_k127_6918292_3 hmm pf07681 K15977 - - 0.00000000000000000000001037 100.0
CMS2_k127_7024834_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367,K00372,K08356 - 1.20.2.1,1.20.9.1,1.7.7.2 0.0 1279.0
CMS2_k127_7024834_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K15576 - - 7.254e-304 931.0
CMS2_k127_7024834_2 Pyridine nucleotide-disulphide oxidoreductase K17229 - 1.8.2.3 2.439e-279 861.0
CMS2_k127_7024834_3 COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 520.0
CMS2_k127_7024834_4 ABC transporter K15555,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 502.0
CMS2_k127_7024834_5 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 464.0
CMS2_k127_7024834_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 317.0
CMS2_k127_7024834_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000000000000008878 234.0
CMS2_k127_7024834_8 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000158 200.0
CMS2_k127_7024834_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000000000000000006653 177.0
CMS2_k127_715359_0 Ribonuclease K12573 - - 1.274e-211 659.0
CMS2_k127_715359_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 525.0
CMS2_k127_715359_2 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 352.0
CMS2_k127_715359_3 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000614 149.0
CMS2_k127_74527_0 - - - - 2.876e-246 760.0
CMS2_k127_74527_1 MORN repeat variant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 422.0
CMS2_k127_74527_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 296.0
CMS2_k127_74527_3 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000006611 189.0
CMS2_k127_759882_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 9.667e-209 651.0
CMS2_k127_759882_1 Transglutaminase-like superfamily K07184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 499.0
CMS2_k127_759882_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 359.0
CMS2_k127_764415_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1361.0
CMS2_k127_764415_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 358.0
CMS2_k127_764415_2 Etoposide-induced protein 2.4 (EI24) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 303.0
CMS2_k127_764415_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 285.0
CMS2_k127_76765_0 PFAM dUTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 445.0
CMS2_k127_76765_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 392.0
CMS2_k127_76765_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000001134 206.0
CMS2_k127_76765_3 beta-lactamase activity K07126 - - 0.000000000000000000000000000000000000000000000000001037 186.0
CMS2_k127_76765_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000003298 152.0
CMS2_k127_833451_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 0.0 1377.0
CMS2_k127_833451_1 - - - - 1.525e-246 765.0
CMS2_k127_833451_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 580.0
CMS2_k127_833451_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 439.0
CMS2_k127_833451_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 394.0
CMS2_k127_833451_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 346.0
CMS2_k127_833451_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000009087 256.0
CMS2_k127_833451_7 - - - - 0.000000000000000000000000000000000000000000000001608 176.0
CMS2_k127_833451_8 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000003788 165.0
CMS2_k127_833451_9 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000005705 68.0
CMS2_k127_833457_0 COG0631 Serine threonine protein phosphatase K12132 - 2.7.11.1 0.0 1031.0
CMS2_k127_833457_1 (twin-arginine translocation) pathway signal - - - 0.0000000000000005364 80.0
CMS2_k127_833457_2 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000005705 68.0
CMS2_k127_886659_0 2-acylglycerophosphoethanolamine acyltransferase K05939 - 2.3.1.40,6.2.1.20 0.0 1715.0
CMS2_k127_886659_1 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 333.0
CMS2_k127_886659_2 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 314.0