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Overview

ID MAG00447
Name CMS2_bin.60
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order SZUA-229
Family SZUA-229
Genus JAUVDT01
Species
Assembly information
Completeness (%) 93.76
Contamination (%) 6.53
GC content (%) 42.0
N50 (bp) 55,948
Genome size (bp) 3,457,410

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3156

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1026570_0 Belongs to the peptidase S16 family - - - 2.449e-292 918.0
CMS2_k127_1026570_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 6.833e-238 744.0
CMS2_k127_1026570_10 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 355.0
CMS2_k127_1026570_11 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 341.0
CMS2_k127_1026570_12 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 343.0
CMS2_k127_1026570_13 Murein peptide amidase A K14054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 323.0
CMS2_k127_1026570_14 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 306.0
CMS2_k127_1026570_15 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 329.0
CMS2_k127_1026570_16 Metallo-beta-lactamase superfamily K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 306.0
CMS2_k127_1026570_17 Belongs to the glucose-6-phosphate 1-epimerase family K01792 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001284 278.0
CMS2_k127_1026570_18 PFAM Cold-shock protein, DNA-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001663 258.0
CMS2_k127_1026570_19 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000002216 237.0
CMS2_k127_1026570_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 4.85e-225 701.0
CMS2_k127_1026570_20 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000005673 234.0
CMS2_k127_1026570_21 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000006254 165.0
CMS2_k127_1026570_22 Domain of unknown function (DUF4824) - - - 0.00000000000000000000000000000000000001973 154.0
CMS2_k127_1026570_23 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000002152 149.0
CMS2_k127_1026570_24 PFAM Outer membrane lipoprotein Slp K07285 - - 0.0000000000000000000000000000000004722 136.0
CMS2_k127_1026570_25 PFAM Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000000000000008115 134.0
CMS2_k127_1026570_26 - - - - 0.00000000000000000002456 95.0
CMS2_k127_1026570_27 Sporulation related domain K03749 - - 0.000000000000000002119 91.0
CMS2_k127_1026570_28 protein histidine kinase activity - - - 0.000002342 58.0
CMS2_k127_1026570_29 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.000003367 58.0
CMS2_k127_1026570_3 protein conserved in bacteria K09800 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347 - 6.943e-194 649.0
CMS2_k127_1026570_30 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00004116 48.0
CMS2_k127_1026570_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 574.0
CMS2_k127_1026570_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 538.0
CMS2_k127_1026570_6 POTRA domain TamA domain 1 K07277,K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 488.0
CMS2_k127_1026570_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 434.0
CMS2_k127_1026570_8 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 417.0
CMS2_k127_1026570_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009202 385.0
CMS2_k127_1033473_0 COG1157 Flagellar biosynthesis type III secretory pathway ATPase K02412 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 477.0
CMS2_k127_1033473_1 response regulator K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 466.0
CMS2_k127_1033473_10 Flagellar protein FliS K02422 - - 0.00000000182 64.0
CMS2_k127_1033473_2 Sigma-54 interaction domain K10941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 455.0
CMS2_k127_1033473_3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 436.0
CMS2_k127_1033473_4 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 413.0
CMS2_k127_1033473_5 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 341.0
CMS2_k127_1033473_6 Histidine kinase K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001974 231.0
CMS2_k127_1033473_7 flagellar protein FliS K02422 - - 0.0000000000000000000000000000000001395 137.0
CMS2_k127_1033473_8 PFAM Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000000000001139 113.0
CMS2_k127_1033473_9 Flagellar assembly protein K02411 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000001638 89.0
CMS2_k127_1033873_0 Allophanate hydrolase subunit 1 K01941 - 6.3.4.6 0.0 1675.0
CMS2_k127_1033873_1 GTP-binding protein TypA K06207 - - 1.308e-295 916.0
CMS2_k127_1033873_10 PFAM ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 489.0
CMS2_k127_1033873_11 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 482.0
CMS2_k127_1033873_12 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 447.0
CMS2_k127_1033873_13 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 445.0
CMS2_k127_1033873_14 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 440.0
CMS2_k127_1033873_15 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 413.0
CMS2_k127_1033873_16 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 396.0
CMS2_k127_1033873_17 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 379.0
CMS2_k127_1033873_18 FAD dependent oxidoreductase K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 372.0
CMS2_k127_1033873_19 Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 357.0
CMS2_k127_1033873_2 Belongs to the IlvD Edd family K01690 - 4.2.1.12 2.663e-251 789.0
CMS2_k127_1033873_20 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 353.0
CMS2_k127_1033873_21 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 292.0
CMS2_k127_1033873_22 LrgB-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 287.0
CMS2_k127_1033873_23 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase K01625 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008675,GO:0008700,GO:0008948,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0106009 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000008888 252.0
CMS2_k127_1033873_24 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000002128 225.0
CMS2_k127_1033873_25 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000006509 224.0
CMS2_k127_1033873_26 NikR C terminal nickel binding domain K07722 - - 0.000000000000000000000000000000000000000000000000000268 188.0
CMS2_k127_1033873_27 Protein of unknown function (DUF1631) - - - 0.00000000000000000000000000000000000000000000000008193 201.0
CMS2_k127_1033873_28 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000007829 181.0
CMS2_k127_1033873_29 unsaturated fatty acid biosynthetic process K00508 GO:0001676,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016213,GO:0016215,GO:0016491,GO:0016705,GO:0016717,GO:0019752,GO:0032787,GO:0042759,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:0072330,GO:1901576 1.14.19.3 0.000000000000000000000000000000000000000000005257 173.0
CMS2_k127_1033873_3 Amidase K01457 - 3.5.1.54 5.945e-218 692.0
CMS2_k127_1033873_30 HEAT repeats - - - 0.00000000000000000000000000000000000000000009673 167.0
CMS2_k127_1033873_31 PFAM LrgA K06518 - - 0.000000000000000000000000000001365 124.0
CMS2_k127_1033873_32 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000006482 123.0
CMS2_k127_1033873_33 Peptidyl-prolyl cis-trans K03774 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000002271 108.0
CMS2_k127_1033873_34 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000001652 109.0
CMS2_k127_1033873_35 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000001072 96.0
CMS2_k127_1033873_36 Membrane fusogenic activity K09806 - - 0.0000000000000001005 82.0
CMS2_k127_1033873_37 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0000000000000001782 81.0
CMS2_k127_1033873_38 Type II transport protein GspH K08084 - - 0.000000000000005991 83.0
CMS2_k127_1033873_39 pilus modification protein PilV K02671 - - 0.000000000008122 72.0
CMS2_k127_1033873_4 Tfp pilus assembly protein tip-associated adhesin K02674 - - 8.092e-194 649.0
CMS2_k127_1033873_40 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000009959 71.0
CMS2_k127_1033873_41 Type IV pilus assembly protein PilX C-term K02673 - - 0.00004861 51.0
CMS2_k127_1033873_5 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 610.0
CMS2_k127_1033873_6 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 587.0
CMS2_k127_1033873_7 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 548.0
CMS2_k127_1033873_8 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 535.0
CMS2_k127_1033873_9 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 516.0
CMS2_k127_1051025_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 497.0
CMS2_k127_1051025_1 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000001461 260.0
CMS2_k127_107363_0 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 374.0
CMS2_k127_107363_1 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 346.0
CMS2_k127_107363_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
CMS2_k127_107363_3 Homocysteine S-methyltransferase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000001563 139.0
CMS2_k127_107363_4 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000000000007626 133.0
CMS2_k127_107363_5 - - - - 0.00000000000001466 76.0
CMS2_k127_1079523_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.0 1026.0
CMS2_k127_1079523_1 Histidine kinase K02482,K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003394 288.0
CMS2_k127_1079523_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000001125 137.0
CMS2_k127_1079523_3 SMART Diguanylate phosphodiesterase - - - 0.000000002574 58.0
CMS2_k127_1114440_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005126 279.0
CMS2_k127_1114440_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000009781 225.0
CMS2_k127_1114440_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000003333 214.0
CMS2_k127_1114440_3 esterase K07000 - - 0.000000000000000000000000000000000000000000000000002717 188.0
CMS2_k127_1114440_4 Belongs to the bacterial histone-like protein family - - - 0.000000000000000000000000000001104 126.0
CMS2_k127_1127547_0 Fumarate reductase flavoprotein C-term K00394 - 1.8.99.2 3.834e-289 896.0
CMS2_k127_1127547_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.131e-288 892.0
CMS2_k127_1127547_10 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 503.0
CMS2_k127_1127547_11 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 483.0
CMS2_k127_1127547_12 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 461.0
CMS2_k127_1127547_13 PFAM Cation K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 459.0
CMS2_k127_1127547_14 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 424.0
CMS2_k127_1127547_15 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 411.0
CMS2_k127_1127547_16 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 406.0
CMS2_k127_1127547_17 Rubredoxin K05297 - 1.18.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 402.0
CMS2_k127_1127547_18 COG0501 Zn-dependent protease with chaperone function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 402.0
CMS2_k127_1127547_19 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 366.0
CMS2_k127_1127547_2 Spermidine putrescine-binding periplasmic protein K02055 - - 3.382e-219 686.0
CMS2_k127_1127547_20 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 363.0
CMS2_k127_1127547_21 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 362.0
CMS2_k127_1127547_22 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 364.0
CMS2_k127_1127547_23 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050,K15552,K15554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 346.0
CMS2_k127_1127547_24 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 338.0
CMS2_k127_1127547_25 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 326.0
CMS2_k127_1127547_26 histidine utilization repressor K03710,K05836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 302.0
CMS2_k127_1127547_27 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 293.0
CMS2_k127_1127547_28 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000149 286.0
CMS2_k127_1127547_29 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001871 273.0
CMS2_k127_1127547_3 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 591.0
CMS2_k127_1127547_30 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006949 263.0
CMS2_k127_1127547_31 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001599 263.0
CMS2_k127_1127547_32 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003185 266.0
CMS2_k127_1127547_33 COG2200 FOG EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001649 269.0
CMS2_k127_1127547_34 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001505 255.0
CMS2_k127_1127547_35 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001945 256.0
CMS2_k127_1127547_36 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003 249.0
CMS2_k127_1127547_37 Lipase (class 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003313 239.0
CMS2_k127_1127547_38 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000003158 234.0
CMS2_k127_1127547_39 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000000000000000000000000000000000000000000000000000000003215 223.0
CMS2_k127_1127547_4 ABC transporter substrate-binding protein K02051,K15553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 592.0
CMS2_k127_1127547_40 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000000000000000000000000000000000000001269 218.0
CMS2_k127_1127547_41 Phospholipase K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000002109 197.0
CMS2_k127_1127547_42 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000537 190.0
CMS2_k127_1127547_43 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000003983 179.0
CMS2_k127_1127547_44 Gram-negative porin - - - 0.000000000000000000000000000000000000000000003866 179.0
CMS2_k127_1127547_45 Cyclic nucleotide-binding domain - - - 0.0000000000000000000000000000000000000004503 157.0
CMS2_k127_1127547_46 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000000339 151.0
CMS2_k127_1127547_47 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000005584 145.0
CMS2_k127_1127547_48 COG2863 Cytochrome c553 - - - 0.000000000000000000000000000000000006802 145.0
CMS2_k127_1127547_49 - - - - 0.00000000000000000000000000000000001653 143.0
CMS2_k127_1127547_5 Fis Family K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 587.0
CMS2_k127_1127547_50 Conserved Protein - - - 0.0000000000000000000000000000000004061 138.0
CMS2_k127_1127547_51 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000007911 141.0
CMS2_k127_1127547_52 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000009395 134.0
CMS2_k127_1127547_53 Sh3 type 3 domain protein - - - 0.000000000000000000000000000000004163 137.0
CMS2_k127_1127547_54 Ferredoxin - - - 0.00000000000000000000000000000001717 127.0
CMS2_k127_1127547_55 YMGG-like Gly-zipper - - - 0.00000000000000000000000000002056 124.0
CMS2_k127_1127547_56 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000004368 124.0
CMS2_k127_1127547_57 - - - - 0.0000000000000000001736 94.0
CMS2_k127_1127547_58 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000009361 74.0
CMS2_k127_1127547_59 Sel1-like repeats. K07126 - - 0.000000000002258 77.0
CMS2_k127_1127547_6 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 578.0
CMS2_k127_1127547_60 - - - - 0.00000000001565 73.0
CMS2_k127_1127547_61 Bacterial transcription activator, effector binding domain - - - 0.0000000003312 67.0
CMS2_k127_1127547_62 - - - - 0.00009064 54.0
CMS2_k127_1127547_63 Outer membrane protein beta-barrel domain - - - 0.0005251 48.0
CMS2_k127_1127547_64 Protein of unknown function (DUF2892) - - - 0.0009165 42.0
CMS2_k127_1127547_7 Dehydrogenase K12957,K13979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 562.0
CMS2_k127_1127547_8 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 552.0
CMS2_k127_1127547_9 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 537.0
CMS2_k127_1138447_0 PFAM Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 436.0
CMS2_k127_1138447_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 295.0
CMS2_k127_1138447_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000002459 178.0
CMS2_k127_1138447_3 CDP-archaeol synthase K19664 - 2.7.7.67 0.000000000000000000000000000000000000000002408 162.0
CMS2_k127_1210238_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1640.0
CMS2_k127_1210238_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 4.991e-302 934.0
CMS2_k127_1210238_10 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 480.0
CMS2_k127_1210238_11 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 451.0
CMS2_k127_1210238_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 443.0
CMS2_k127_1210238_13 response regulator receiver K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 419.0
CMS2_k127_1210238_14 DMSO reductase anchor subunit (DmsC) K21309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 381.0
CMS2_k127_1210238_15 Protein of unknown function (DUF3050) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 355.0
CMS2_k127_1210238_16 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 344.0
CMS2_k127_1210238_17 Belongs to the UPF0246 family K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 333.0
CMS2_k127_1210238_18 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 323.0
CMS2_k127_1210238_19 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 341.0
CMS2_k127_1210238_2 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 1.798e-239 748.0
CMS2_k127_1210238_20 NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 295.0
CMS2_k127_1210238_21 Nucleoside triphosphate K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001941 267.0
CMS2_k127_1210238_22 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006983 263.0
CMS2_k127_1210238_23 Protein of unknown function (DUF3025) - - - 0.0000000000000000000000000000000000000000000000000000004081 203.0
CMS2_k127_1210238_24 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000003954 186.0
CMS2_k127_1210238_25 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000001799 183.0
CMS2_k127_1210238_26 Histidine kinase - - - 0.000000000000000000000000000000000000000000002435 183.0
CMS2_k127_1210238_27 Surface antigen - - - 0.00000000000000000000000000000000000000001271 169.0
CMS2_k127_1210238_28 membrane - - - 0.0000000000000000000000000000000005274 132.0
CMS2_k127_1210238_29 Cupin - - - 0.0000000000000000000000000000000009139 133.0
CMS2_k127_1210238_3 Protein of unknown function, DUF255 K06888 - - 6.831e-227 722.0
CMS2_k127_1210238_30 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000008518 132.0
CMS2_k127_1210238_32 - - - - 0.00000007399 59.0
CMS2_k127_1210238_33 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00002414 53.0
CMS2_k127_1210238_34 - - - - 0.0006968 44.0
CMS2_k127_1210238_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 4.591e-209 657.0
CMS2_k127_1210238_5 Putative nucleotidyltransferase substrate binding domain K07182 - - 8.888e-201 642.0
CMS2_k127_1210238_6 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 4.154e-198 624.0
CMS2_k127_1210238_7 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 537.0
CMS2_k127_1210238_8 4Fe-4S dicluster domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 489.0
CMS2_k127_1210238_9 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 485.0
CMS2_k127_1222493_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1528.0
CMS2_k127_1222493_1 Von willebrand factor, type a - - - 0.0 1037.0
CMS2_k127_1222493_10 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 433.0
CMS2_k127_1222493_11 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 427.0
CMS2_k127_1222493_12 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 408.0
CMS2_k127_1222493_13 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 384.0
CMS2_k127_1222493_14 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 376.0
CMS2_k127_1222493_15 HAD-hyrolase-like K01091 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 337.0
CMS2_k127_1222493_16 COG0512 Anthranilate para-aminobenzoate synthases component II K01658,K01664 GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 330.0
CMS2_k127_1222493_17 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 329.0
CMS2_k127_1222493_18 drug resistance transporter Bcr CflA subfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 333.0
CMS2_k127_1222493_19 ion transport protein K08714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 322.0
CMS2_k127_1222493_2 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 1.698e-288 888.0
CMS2_k127_1222493_20 Copper resistance protein B precursor (CopB) K07233 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004722 276.0
CMS2_k127_1222493_21 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003286 283.0
CMS2_k127_1222493_22 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003904 275.0
CMS2_k127_1222493_23 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001707 249.0
CMS2_k127_1222493_24 Protein of unknown function (DUF3187) - - - 0.00000000000000000000000000000000000000000000000000000000004627 217.0
CMS2_k127_1222493_25 Transcriptional regulator, AraC family - - - 0.0000000000000000000000000000000000000000000000000000000007547 206.0
CMS2_k127_1222493_26 AsnC family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000004858 193.0
CMS2_k127_1222493_27 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000006826 200.0
CMS2_k127_1222493_28 Copper resistance protein D - - - 0.00000000000000000000000000000000000000000000000000223 186.0
CMS2_k127_1222493_29 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000000000000000000000003624 164.0
CMS2_k127_1222493_3 P-type ATPase K17686 - 3.6.3.54 1.291e-276 870.0
CMS2_k127_1222493_30 diguanylate cyclase - - - 0.00000000000000000000000000000000000000001071 171.0
CMS2_k127_1222493_31 Cupredoxin-like domain - - - 0.0000000000000000000000000000001784 127.0
CMS2_k127_1222493_32 Cytochrome c, class I - - - 0.000000000000000000000000000003459 125.0
CMS2_k127_1222493_33 Cytochrome c - - - 0.000000000000000000000000000003966 124.0
CMS2_k127_1222493_34 Cytochrome c - - - 0.000000000000000000000000001082 116.0
CMS2_k127_1222493_35 - - - - 0.0000000000000000000000756 103.0
CMS2_k127_1222493_36 Histidine kinase - - - 0.0000000000000002513 85.0
CMS2_k127_1222493_37 TPR repeat - - - 0.000000000000002274 86.0
CMS2_k127_1222493_38 Short C-terminal domain K08982 - - 0.000000002332 61.0
CMS2_k127_1222493_39 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000005622 57.0
CMS2_k127_1222493_4 Multicopper oxidase - - - 6.251e-271 848.0
CMS2_k127_1222493_40 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K22110 - - 0.0000001468 63.0
CMS2_k127_1222493_5 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.636e-226 711.0
CMS2_k127_1222493_6 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 581.0
CMS2_k127_1222493_7 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 472.0
CMS2_k127_1222493_8 ATPase associated with various cellular activities AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 453.0
CMS2_k127_1222493_9 HlyD membrane-fusion protein of T1SS K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 446.0
CMS2_k127_1234912_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 2.442e-224 703.0
CMS2_k127_1234912_1 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 3.356e-198 651.0
CMS2_k127_1234912_10 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000002307 173.0
CMS2_k127_1234912_11 Membrane - - - 0.000000000000000000000000000000000000000000002002 168.0
CMS2_k127_1234912_12 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000009273 158.0
CMS2_k127_1234912_13 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000001146 158.0
CMS2_k127_1234912_14 protein disulfide oxidoreductase activity - - - 0.00000000000000000000000000000000000000001609 161.0
CMS2_k127_1234912_15 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000001355 136.0
CMS2_k127_1234912_16 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000004403 118.0
CMS2_k127_1234912_17 Tetratricopeptide repeat - - - 0.0000000000000000000004519 111.0
CMS2_k127_1234912_18 SH3 domain protein - - - 0.000000000000000000005066 102.0
CMS2_k127_1234912_19 - - - - 0.0000000000000005664 85.0
CMS2_k127_1234912_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 614.0
CMS2_k127_1234912_20 Tetratricopeptide repeat - - - 0.00000000000001648 81.0
CMS2_k127_1234912_21 Protein of unknown function (DUF2390) - - - 0.0000000007242 66.0
CMS2_k127_1234912_22 - - - - 0.00000002527 58.0
CMS2_k127_1234912_23 Putative peptidoglycan binding domain - - - 0.000002423 54.0
CMS2_k127_1234912_24 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0006343 43.0
CMS2_k127_1234912_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 513.0
CMS2_k127_1234912_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 476.0
CMS2_k127_1234912_5 PFAM Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 365.0
CMS2_k127_1234912_6 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 351.0
CMS2_k127_1234912_7 membrane protein involved in D-alanine export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 329.0
CMS2_k127_1234912_8 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001649 247.0
CMS2_k127_1234912_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000003862 193.0
CMS2_k127_1248104_0 Pentapeptide repeat K15352,K18555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 491.0
CMS2_k127_1248104_1 Domain of unknown function (DUF4150) - - - 0.000000000000000000000000000000000000000000000000006588 184.0
CMS2_k127_1248104_2 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000000007519 134.0
CMS2_k127_1248104_3 Protein of unknown function (DUF3540) - - - 0.00000000000000000000000001421 117.0
CMS2_k127_1248104_4 Hemolysin activation secretion protein - - - 0.000000000206 69.0
CMS2_k127_1256831_0 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 409.0
CMS2_k127_1256831_1 haemagglutination activity domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 406.0
CMS2_k127_1256831_2 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 392.0
CMS2_k127_1256831_3 Hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002182 270.0
CMS2_k127_1256831_4 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000172 257.0
CMS2_k127_1256831_5 Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000002898 232.0
CMS2_k127_1270224_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 1.114e-273 860.0
CMS2_k127_1270224_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 6.716e-249 786.0
CMS2_k127_1270224_10 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 530.0
CMS2_k127_1270224_11 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 523.0
CMS2_k127_1270224_12 PFAM Type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 490.0
CMS2_k127_1270224_13 Belongs to the peptidase S1C family K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 459.0
CMS2_k127_1270224_14 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 443.0
CMS2_k127_1270224_15 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 437.0
CMS2_k127_1270224_16 COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 418.0
CMS2_k127_1270224_17 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 385.0
CMS2_k127_1270224_18 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 409.0
CMS2_k127_1270224_19 COG1194 A G-specific DNA glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 387.0
CMS2_k127_1270224_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 6.704e-233 730.0
CMS2_k127_1270224_20 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 381.0
CMS2_k127_1270224_21 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 371.0
CMS2_k127_1270224_22 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 360.0
CMS2_k127_1270224_23 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 311.0
CMS2_k127_1270224_24 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 308.0
CMS2_k127_1270224_25 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 301.0
CMS2_k127_1270224_26 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 301.0
CMS2_k127_1270224_27 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 288.0
CMS2_k127_1270224_28 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 291.0
CMS2_k127_1270224_29 phenylacetate-CoA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002024 276.0
CMS2_k127_1270224_3 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 1.231e-207 664.0
CMS2_k127_1270224_30 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002355 275.0
CMS2_k127_1270224_31 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003711 273.0
CMS2_k127_1270224_32 CBS-domain-containing membrane protein K07168 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003615 274.0
CMS2_k127_1270224_33 PFAM YicC-like family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005221 273.0
CMS2_k127_1270224_34 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001265 258.0
CMS2_k127_1270224_35 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001089 253.0
CMS2_k127_1270224_36 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000002286 254.0
CMS2_k127_1270224_37 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004717 257.0
CMS2_k127_1270224_38 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000000000000002909 242.0
CMS2_k127_1270224_39 Uncharacterised protein family (UPF0014) K02069 - - 0.00000000000000000000000000000000000000000000000000000000000000002547 230.0
CMS2_k127_1270224_4 PFAM Type II secretion system protein E K02669 - - 2.616e-194 608.0
CMS2_k127_1270224_40 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000002965 226.0
CMS2_k127_1270224_41 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000000000000000000003232 221.0
CMS2_k127_1270224_42 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000001249 216.0
CMS2_k127_1270224_43 - - - - 0.000000000000000000000000000000000000000000000000000000000001287 213.0
CMS2_k127_1270224_44 rRNA (Guanine-N1-)-methyltransferase K00563 - 2.1.1.187 0.000000000000000000000000000000000000000000000000000000000002288 218.0
CMS2_k127_1270224_45 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000002235 208.0
CMS2_k127_1270224_46 pfam ammecr1 - - - 0.0000000000000000000000000000000000000000000000000000001943 200.0
CMS2_k127_1270224_47 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000003861 191.0
CMS2_k127_1270224_48 FKBP-type peptidyl-prolyl isomerase K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000004354 192.0
CMS2_k127_1270224_49 Peptidase C26 - - - 0.0000000000000000000000000000000000000000000000000005705 191.0
CMS2_k127_1270224_5 PFAM Type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 609.0
CMS2_k127_1270224_50 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000001575 190.0
CMS2_k127_1270224_51 integral membrane protein K02221 - - 0.000000000000000000000000000000000000000000000000005765 186.0
CMS2_k127_1270224_52 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000009399 175.0
CMS2_k127_1270224_53 Spondin_N - - - 0.0000000000000000000000000000000000000000001175 167.0
CMS2_k127_1270224_54 Belongs to the bacterial histone-like protein family - - - 0.00000000000000000000000000000000000000001638 158.0
CMS2_k127_1270224_55 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.000000000000000000000000000000000000006071 151.0
CMS2_k127_1270224_56 Histidine kinase - - - 0.0000000000000000000000000000000001369 153.0
CMS2_k127_1270224_57 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000002052 125.0
CMS2_k127_1270224_58 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000000003189 127.0
CMS2_k127_1270224_59 Bacterial Fe(2+) trafficking - - - 0.00000000000000000000000000001767 119.0
CMS2_k127_1270224_6 radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 606.0
CMS2_k127_1270224_60 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000036 118.0
CMS2_k127_1270224_61 Two component regulator propeller - - - 0.000000000000000000000000162 116.0
CMS2_k127_1270224_62 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000006148 112.0
CMS2_k127_1270224_63 DUF167 - - - 0.000000000000000000000001328 106.0
CMS2_k127_1270224_64 Domain of unknown function (DUF4389) - - - 0.000000000000000000000002979 105.0
CMS2_k127_1270224_65 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000003118 89.0
CMS2_k127_1270224_7 PFAM sodium alanine symporter K03310 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 613.0
CMS2_k127_1270224_8 Sulfatase K03760 - 2.7.8.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 576.0
CMS2_k127_1270224_9 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 565.0
CMS2_k127_1284548_0 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 1.647e-291 915.0
CMS2_k127_1284548_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 4.73e-265 820.0
CMS2_k127_1284548_10 cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 308.0
CMS2_k127_1284548_11 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 305.0
CMS2_k127_1284548_12 COG0405 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000002899 245.0
CMS2_k127_1284548_13 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000254 214.0
CMS2_k127_1284548_14 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000004459 208.0
CMS2_k127_1284548_15 FixH - - - 0.0000000000000000000000000000000000000000000000000000000174 207.0
CMS2_k127_1284548_16 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000537 190.0
CMS2_k127_1284548_17 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000009068 184.0
CMS2_k127_1284548_18 Ferredoxin - - - 0.00000000000000000000000000000000000000000002928 162.0
CMS2_k127_1284548_19 COG1716 FOG FHA domain - - - 0.000000000000000000000004222 106.0
CMS2_k127_1284548_2 TIGRFAM cytochrome c oxidase accessory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 534.0
CMS2_k127_1284548_20 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000666 99.0
CMS2_k127_1284548_21 Cytochrome oxidase maturation protein - - - 0.0000000000000001495 81.0
CMS2_k127_1284548_22 Cbb3-type cytochrome oxidase component FixQ - - - 0.000000000002243 70.0
CMS2_k127_1284548_23 WD40-like Beta Propeller Repeat K03641 - - 0.000000002994 69.0
CMS2_k127_1284548_3 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 477.0
CMS2_k127_1284548_4 PFAM Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 432.0
CMS2_k127_1284548_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 417.0
CMS2_k127_1284548_6 PFAM Cytochrome C oxidase, monoheme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 395.0
CMS2_k127_1284548_7 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 385.0
CMS2_k127_1284548_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 336.0
CMS2_k127_1284548_9 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 321.0
CMS2_k127_1298552_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0 1783.0
CMS2_k127_1298552_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1102.0
CMS2_k127_1298552_10 Belongs to the GARS family K01945 - 6.3.4.13 4.751e-212 664.0
CMS2_k127_1298552_11 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 5.47e-205 655.0
CMS2_k127_1298552_12 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 608.0
CMS2_k127_1298552_13 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 550.0
CMS2_k127_1298552_14 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 459.0
CMS2_k127_1298552_15 Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 437.0
CMS2_k127_1298552_16 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 434.0
CMS2_k127_1298552_17 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 431.0
CMS2_k127_1298552_18 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 389.0
CMS2_k127_1298552_19 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 356.0
CMS2_k127_1298552_2 Carbon-nitrogen hydrolase - - - 5.483e-290 894.0
CMS2_k127_1298552_20 involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 334.0
CMS2_k127_1298552_21 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 327.0
CMS2_k127_1298552_22 type I secretion outer membrane protein, TolC K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 330.0
CMS2_k127_1298552_23 Ribosomal protein L11 methyltransferase K02687 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 320.0
CMS2_k127_1298552_24 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 297.0
CMS2_k127_1298552_25 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001419 284.0
CMS2_k127_1298552_26 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003987 274.0
CMS2_k127_1298552_27 Bacterial Ig-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005262 284.0
CMS2_k127_1298552_28 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000005812 257.0
CMS2_k127_1298552_29 O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000008562 243.0
CMS2_k127_1298552_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.369e-279 865.0
CMS2_k127_1298552_30 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000003292 239.0
CMS2_k127_1298552_31 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001064 229.0
CMS2_k127_1298552_32 Nucleoside 2-deoxyribosyltransferase YtoQ - - - 0.000000000000000000000000000000000000000000000000000000000000000001564 229.0
CMS2_k127_1298552_33 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000001215 206.0
CMS2_k127_1298552_34 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.0000000000000000000000000000000000000000000000000000000003101 211.0
CMS2_k127_1298552_35 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000003729 199.0
CMS2_k127_1298552_36 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000000006239 197.0
CMS2_k127_1298552_37 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000005001 182.0
CMS2_k127_1298552_38 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000000000000000009194 176.0
CMS2_k127_1298552_39 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000004129 175.0
CMS2_k127_1298552_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.532e-257 803.0
CMS2_k127_1298552_40 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000001399 171.0
CMS2_k127_1298552_41 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000005602 155.0
CMS2_k127_1298552_42 DoxX K15977 - - 0.000000000000000000000000000000000000000006134 158.0
CMS2_k127_1298552_43 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000008597 155.0
CMS2_k127_1298552_44 MltA-interacting protein MipA - - - 0.0000000000000000000000000000000000000000855 160.0
CMS2_k127_1298552_45 molecular chaperone - - - 0.0000000000000000000000000000000000000004635 156.0
CMS2_k127_1298552_46 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000000000006004 132.0
CMS2_k127_1298552_47 Alpha beta hydrolase - - - 0.00000000000000000000000000000002257 135.0
CMS2_k127_1298552_48 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000007668 132.0
CMS2_k127_1298552_49 COG3030 Protein affecting phage T7 exclusion by the F plasmid K07113 - - 0.000000000000000000000000000643 119.0
CMS2_k127_1298552_5 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 2.886e-236 736.0
CMS2_k127_1298552_51 Type IX secretion system membrane protein PorP/SprF - - - 0.0000000000000000000000288 113.0
CMS2_k127_1298552_52 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000009978 93.0
CMS2_k127_1298552_53 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000001877 94.0
CMS2_k127_1298552_54 - - - - 0.000000000000000001179 89.0
CMS2_k127_1298552_56 - - - - 0.000000000000003727 79.0
CMS2_k127_1298552_57 small protein containing a coiled-coil domain - - - 0.00000000000001318 75.0
CMS2_k127_1298552_58 carboxylic ester hydrolase activity - - - 0.000002243 56.0
CMS2_k127_1298552_6 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.15e-234 729.0
CMS2_k127_1298552_7 Diguanylate cyclase - - - 7.343e-221 700.0
CMS2_k127_1298552_8 Peptidase U32 K08303 - - 2.253e-219 687.0
CMS2_k127_1298552_9 ABC transporter K06158 - - 4.378e-215 685.0
CMS2_k127_1322147_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1328.0
CMS2_k127_1322147_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 0.0 1239.0
CMS2_k127_1322147_10 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 594.0
CMS2_k127_1322147_11 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 593.0
CMS2_k127_1322147_12 Bacterial type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 578.0
CMS2_k127_1322147_13 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 561.0
CMS2_k127_1322147_14 flavoproteins K07007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008663 532.0
CMS2_k127_1322147_15 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 550.0
CMS2_k127_1322147_16 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0071704,GO:1901564,GO:1902494 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 503.0
CMS2_k127_1322147_17 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 505.0
CMS2_k127_1322147_18 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 466.0
CMS2_k127_1322147_19 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 465.0
CMS2_k127_1322147_2 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1158.0
CMS2_k127_1322147_20 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 445.0
CMS2_k127_1322147_21 TIGRFAM general secretion pathway protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 447.0
CMS2_k127_1322147_22 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 432.0
CMS2_k127_1322147_23 Amino Acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 413.0
CMS2_k127_1322147_24 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 341.0
CMS2_k127_1322147_25 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 329.0
CMS2_k127_1322147_26 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 301.0
CMS2_k127_1322147_27 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003373 273.0
CMS2_k127_1322147_28 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000007171 233.0
CMS2_k127_1322147_29 PFAM Metal-dependent hydrolase HDOD - - - 0.0000000000000000000000000000000000000000000000000000001102 211.0
CMS2_k127_1322147_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 8.604e-243 764.0
CMS2_k127_1322147_30 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000004577 189.0
CMS2_k127_1322147_31 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000003322 183.0
CMS2_k127_1322147_32 Glutaredoxin - - - 0.0000000000000000000000000000000000000000007715 160.0
CMS2_k127_1322147_33 Ribosomal protein L11 methyltransferase (PrmA) K11434 - 2.1.1.319 0.0000000000000000000000000000000000000003418 162.0
CMS2_k127_1322147_34 COG0784 FOG CheY-like receiver - - - 0.000000000000000000000000000000000000000373 152.0
CMS2_k127_1322147_35 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000005198 149.0
CMS2_k127_1322147_36 Family of unknown function (DUF695) - - - 0.0000000000000000000000000000000000000005809 152.0
CMS2_k127_1322147_37 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000004456 146.0
CMS2_k127_1322147_38 TIGRFAM general secretion pathway protein C K02452 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000000000001196 129.0
CMS2_k127_1322147_39 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001287 119.0
CMS2_k127_1322147_4 PFAM FAD dependent oxidoreductase K00116 - 1.1.5.4 4.963e-213 669.0
CMS2_k127_1322147_40 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000002646 109.0
CMS2_k127_1322147_41 FKBP-type peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.000000000000000002557 87.0
CMS2_k127_1322147_42 Rhodanese Homology Domain - - - 0.00000000000005621 78.0
CMS2_k127_1322147_43 Protein of unknown function (DUF3301) - - - 0.000000000002045 71.0
CMS2_k127_1322147_45 Histidine Phosphotransfer domain - - - 0.000002813 54.0
CMS2_k127_1322147_46 Protein of unknown function (DUF1186) - - - 0.0006418 51.0
CMS2_k127_1322147_5 Belongs to the phosphoglycerate kinase family K00927 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 1.377e-210 659.0
CMS2_k127_1322147_6 PFAM Type II secretion system protein E K02454 - - 2.071e-206 652.0
CMS2_k127_1322147_7 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.634e-199 631.0
CMS2_k127_1322147_8 Aldolase K01624 - 4.1.2.13 2.576e-197 617.0
CMS2_k127_1322147_9 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 607.0
CMS2_k127_1381296_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase - - - 0.0 1196.0
CMS2_k127_1381296_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1059.0
CMS2_k127_1381296_10 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 565.0
CMS2_k127_1381296_11 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 557.0
CMS2_k127_1381296_12 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 490.0
CMS2_k127_1381296_13 Belongs to the ParA family K03609 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0007059,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051782,GO:0060187,GO:0065007,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 437.0
CMS2_k127_1381296_14 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 412.0
CMS2_k127_1381296_15 PFAM Transglutaminase-like superfamily K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 414.0
CMS2_k127_1381296_16 Glycosyl transferase - GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 394.0
CMS2_k127_1381296_17 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 383.0
CMS2_k127_1381296_18 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 369.0
CMS2_k127_1381296_19 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 355.0
CMS2_k127_1381296_2 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0003674,GO:0003824,GO:0004474,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350 2.3.3.9 1.784e-300 937.0
CMS2_k127_1381296_20 Protein of unknown function (DUF2797) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 352.0
CMS2_k127_1381296_21 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 351.0
CMS2_k127_1381296_22 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042,K08319 GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.411,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 336.0
CMS2_k127_1381296_23 L-malate dehydrogenase activity K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 328.0
CMS2_k127_1381296_24 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 321.0
CMS2_k127_1381296_25 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 314.0
CMS2_k127_1381296_26 response regulator K20977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 312.0
CMS2_k127_1381296_27 Transcriptional regulator K13641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 293.0
CMS2_k127_1381296_28 Inhibitor of apoptosis-promoting Bax1 K19416 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0019222,GO:0030162,GO:0031224,GO:0044425,GO:0044464,GO:0050789,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071944,GO:0080090 - 0.000000000000000000000000000000000000000000000000000000000000000000000003231 250.0
CMS2_k127_1381296_29 protein conserved in bacteria K09859 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004904 260.0
CMS2_k127_1381296_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 5.235e-247 770.0
CMS2_k127_1381296_30 PFAM Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002156 250.0
CMS2_k127_1381296_31 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000004767 240.0
CMS2_k127_1381296_32 Peptidoglycan-synthase activator LpoB K07337 - - 0.000000000000000000000000000000000000000000000000000000000000000001477 232.0
CMS2_k127_1381296_33 Mate efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000000001697 235.0
CMS2_k127_1381296_34 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000006072 223.0
CMS2_k127_1381296_35 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0007346,GO:0008150,GO:0009987,GO:0010564,GO:0032465,GO:0032954,GO:0032955,GO:0042802,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051726,GO:0060187,GO:0065007,GO:1901891,GO:1902412,GO:1903436 - 0.0000000000000000000000000000000000000000000000000000000004922 209.0
CMS2_k127_1381296_36 aldolase K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000004806 203.0
CMS2_k127_1381296_37 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000002212 193.0
CMS2_k127_1381296_38 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.00000000000000000000000000000000000000000000000000004021 191.0
CMS2_k127_1381296_39 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000009188 198.0
CMS2_k127_1381296_4 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 1.172e-236 747.0
CMS2_k127_1381296_40 transcriptional regulator K09017 - - 0.000000000000000000000000000000000000000000000000001889 189.0
CMS2_k127_1381296_41 aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000000004922 171.0
CMS2_k127_1381296_42 Pfam:DUF162 K00782 - - 0.0000000000000000000000000000000000000000001083 171.0
CMS2_k127_1381296_43 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000001352 158.0
CMS2_k127_1381296_44 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000001659 156.0
CMS2_k127_1381296_45 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000001004 158.0
CMS2_k127_1381296_46 protein, possibly involved in utilization of glycolate and propanediol K11477 - - 0.0000000000000000000000000000000000000006835 153.0
CMS2_k127_1381296_47 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000001204 153.0
CMS2_k127_1381296_48 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000001844 138.0
CMS2_k127_1381296_49 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0007049,GO:0007346,GO:0008150,GO:0009987,GO:0010564,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032465,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051726,GO:0061640,GO:0065007,GO:0071840,GO:0071944,GO:0090529,GO:1901891,GO:1902410,GO:1902412,GO:1903047,GO:1903436 - 0.00000000000000000000000000000001082 128.0
CMS2_k127_1381296_5 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 5.993e-233 731.0
CMS2_k127_1381296_50 LPP20 lipoprotein - - - 0.00000000000000000000000000000006095 138.0
CMS2_k127_1381296_51 Sulfurtransferase TusA - - - 0.0000000000000000000000000000005203 123.0
CMS2_k127_1381296_52 Sterol carrier protein - - - 0.000000000000000000000000000009013 123.0
CMS2_k127_1381296_53 DsrC like protein K11179 - - 0.00000000000000000000000000007532 120.0
CMS2_k127_1381296_54 Fumarylacetoacetate (FAA) hydrolase family K02509 - - 0.000000000000000007317 92.0
CMS2_k127_1381296_55 - - - - 0.000000000562 63.0
CMS2_k127_1381296_56 PhoQ Sensor K03413,K10916 GO:0000155,GO:0000156,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 0.0004311 48.0
CMS2_k127_1381296_6 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 5.867e-227 711.0
CMS2_k127_1381296_7 kinase activity - - - 5.715e-195 616.0
CMS2_k127_1381296_8 Iron-sulfur cluster binding protein K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 613.0
CMS2_k127_1381296_9 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 585.0
CMS2_k127_139051_0 - - - - 0.000000000000000000000000000000000000000000000000000000000002212 226.0
CMS2_k127_139051_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000002719 225.0
CMS2_k127_139051_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000003027 128.0
CMS2_k127_139051_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000005382 101.0
CMS2_k127_1396050_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 3.186e-308 959.0
CMS2_k127_1396050_1 Histidine kinase - - - 5.154e-234 754.0
CMS2_k127_1396050_10 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 394.0
CMS2_k127_1396050_11 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 376.0
CMS2_k127_1396050_12 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 309.0
CMS2_k127_1396050_13 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007136 256.0
CMS2_k127_1396050_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000004354 251.0
CMS2_k127_1396050_15 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000404 247.0
CMS2_k127_1396050_16 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008185 240.0
CMS2_k127_1396050_17 Haemolysin-III related - - - 0.00000000000000000000000000000000000000000000000000000000000000006689 229.0
CMS2_k127_1396050_18 Cytochrome c K00185 - - 0.000000000000000000000000000000000000000000000000000004359 192.0
CMS2_k127_1396050_19 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000004911 172.0
CMS2_k127_1396050_2 Belongs to the RtcB family K14415 - 6.5.1.3 9.434e-224 701.0
CMS2_k127_1396050_20 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000007896 161.0
CMS2_k127_1396050_21 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.000000000000000000000000000000000000006865 149.0
CMS2_k127_1396050_22 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000001895 145.0
CMS2_k127_1396050_23 Protein of unknown function (DUF2953) - - - 0.000000000000000000000000000000000004131 144.0
CMS2_k127_1396050_24 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.00000000000000000000000000000000003363 143.0
CMS2_k127_1396050_25 MlaC protein - - - 0.000000000000000000000000009612 118.0
CMS2_k127_1396050_26 Putative ATP-dependant zinc protease - - - 0.00000000000000000000000008212 113.0
CMS2_k127_1396050_27 Protein of unknown function (DUF2956) - - - 0.0000000000000000000000001343 110.0
CMS2_k127_1396050_3 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 560.0
CMS2_k127_1396050_30 - - - - 0.00000000000000000000955 96.0
CMS2_k127_1396050_31 Putative zinc- or iron-chelating domain - - - 0.00000000000000001339 89.0
CMS2_k127_1396050_4 Adenosine/AMP deaminase K01488,K21053 - 3.5.4.2,3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 503.0
CMS2_k127_1396050_5 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 485.0
CMS2_k127_1396050_6 transferase activity, transferring glycosyl groups K00713,K06338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 458.0
CMS2_k127_1396050_7 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008928 435.0
CMS2_k127_1396050_8 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 421.0
CMS2_k127_1396050_9 Sugar-transfer associated ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 400.0
CMS2_k127_13974_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2184.0
CMS2_k127_13974_1 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 2.436e-267 849.0
CMS2_k127_13974_10 Belongs to the phosphoglycerate mutase family K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 390.0
CMS2_k127_13974_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000001265 205.0
CMS2_k127_13974_12 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000001356 183.0
CMS2_k127_13974_13 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000209 186.0
CMS2_k127_13974_14 - - - - 0.0000000000000000000000000000000000000000000000001186 183.0
CMS2_k127_13974_15 PFAM Fimbrial assembly K02663 - - 0.00000000000000000000000000000000000000000000004995 175.0
CMS2_k127_13974_16 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) K13694,K13695 - 3.4.17.13 0.00000000000000000000000000000000000000000006254 165.0
CMS2_k127_13974_17 COG3168 Tfp pilus assembly protein PilP K02665 - - 0.0000000000000000000000000000000000000008236 154.0
CMS2_k127_13974_18 - - - - 0.000000000000000000000000000000002324 135.0
CMS2_k127_13974_19 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000001159 106.0
CMS2_k127_13974_2 COG0493 NADPH-dependent glutamate synthase beta chain and K00266 - 1.4.1.13,1.4.1.14 1.164e-227 713.0
CMS2_k127_13974_20 N-formylglutamate amidohydrolase - - - 0.0000000000000003234 83.0
CMS2_k127_13974_22 Sel1-like repeats. - - - 0.000004232 59.0
CMS2_k127_13974_23 Domain of unknown function (DUF4124) - - - 0.0001344 46.0
CMS2_k127_13974_3 Secretin and TonB N terminus short domain K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 3.318e-199 643.0
CMS2_k127_13974_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 555.0
CMS2_k127_13974_5 DUF1704 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 509.0
CMS2_k127_13974_6 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 500.0
CMS2_k127_13974_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 492.0
CMS2_k127_13974_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000098 481.0
CMS2_k127_13974_9 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 451.0
CMS2_k127_1432634_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 7.174e-271 860.0
CMS2_k127_1432634_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.098e-255 790.0
CMS2_k127_1432634_10 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 376.0
CMS2_k127_1432634_11 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 366.0
CMS2_k127_1432634_12 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 330.0
CMS2_k127_1432634_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 334.0
CMS2_k127_1432634_14 4Fe-4S single cluster domain K01843,K19810 GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016866,GO:0016869,GO:0048037,GO:0051536,GO:0051539,GO:0051540 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 315.0
CMS2_k127_1432634_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 325.0
CMS2_k127_1432634_16 With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P K04568 GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 305.0
CMS2_k127_1432634_17 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 302.0
CMS2_k127_1432634_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 316.0
CMS2_k127_1432634_19 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 293.0
CMS2_k127_1432634_2 DEAD-box RNA helicase involved in - - - 3.633e-195 617.0
CMS2_k127_1432634_20 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 296.0
CMS2_k127_1432634_21 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 295.0
CMS2_k127_1432634_22 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 293.0
CMS2_k127_1432634_23 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 306.0
CMS2_k127_1432634_24 membrane organization K20543 - - 0.000000000000000000000000000000000000000000000000000007216 206.0
CMS2_k127_1432634_25 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000005266 165.0
CMS2_k127_1432634_26 - - - - 0.000000000000000000000000000001239 124.0
CMS2_k127_1432634_27 cheY-homologous receiver domain - - - 0.0000000000000000000000000007893 116.0
CMS2_k127_1432634_28 protein conserved in bacteria K09796 - - 0.0000000000000000000000003861 112.0
CMS2_k127_1432634_29 cheY-homologous receiver domain K03413 - - 0.000000000000000002008 98.0
CMS2_k127_1432634_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 598.0
CMS2_k127_1432634_30 Phosphoesterase - - - 0.00000000000006469 80.0
CMS2_k127_1432634_31 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000001099 80.0
CMS2_k127_1432634_4 PFAM EAL domain K21025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 574.0
CMS2_k127_1432634_5 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 531.0
CMS2_k127_1432634_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 449.0
CMS2_k127_1432634_7 major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 427.0
CMS2_k127_1432634_8 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 384.0
CMS2_k127_1432634_9 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 380.0
CMS2_k127_144032_0 Protein tyrosine kinase K12132 - 2.7.11.1 1.321e-305 960.0
CMS2_k127_144032_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.579e-241 767.0
CMS2_k127_144032_10 PFAM peptidase S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 334.0
CMS2_k127_144032_11 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 319.0
CMS2_k127_144032_12 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 302.0
CMS2_k127_144032_13 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000007434 265.0
CMS2_k127_144032_14 Protein phosphatase 2C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008361 260.0
CMS2_k127_144032_15 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003226 242.0
CMS2_k127_144032_16 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000005571 226.0
CMS2_k127_144032_17 subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000001017 228.0
CMS2_k127_144032_18 Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000008794 198.0
CMS2_k127_144032_19 esterase K07000 - - 0.0000000000000000000000000000000000000000000000000113 186.0
CMS2_k127_144032_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 6.08e-238 756.0
CMS2_k127_144032_20 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000008655 183.0
CMS2_k127_144032_21 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000002981 172.0
CMS2_k127_144032_22 SMART HNH nuclease - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000006454 168.0
CMS2_k127_144032_23 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000003794 93.0
CMS2_k127_144032_3 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 500.0
CMS2_k127_144032_4 Histidine kinase K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 491.0
CMS2_k127_144032_5 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 462.0
CMS2_k127_144032_6 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 426.0
CMS2_k127_144032_7 COG0668 Small-conductance mechanosensitive channel K16052 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 419.0
CMS2_k127_144032_8 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 379.0
CMS2_k127_144032_9 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 335.0
CMS2_k127_1508014_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K11959 - - 3.994e-228 711.0
CMS2_k127_1508014_1 Acetamidase/Formamidase family K01455 - 3.5.1.49 2.606e-221 690.0
CMS2_k127_1508014_10 Putative regulatory protein - - - 0.0000000000000008517 81.0
CMS2_k127_1508014_2 Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates K01426 - 3.5.1.4 3.795e-219 681.0
CMS2_k127_1508014_3 branched-chain amino acid transport system, permease component K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 599.0
CMS2_k127_1508014_4 urea ABC transporter, permease protein UrtB K11960 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 510.0
CMS2_k127_1508014_5 TIGRFAM urea ABC transporter, ATP-binding protein UrtD K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 411.0
CMS2_k127_1508014_6 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 407.0
CMS2_k127_1508014_7 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 374.0
CMS2_k127_1508014_8 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000004162 191.0
CMS2_k127_1508014_9 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000007465 92.0
CMS2_k127_1641583_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1918.0
CMS2_k127_1641583_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1587.0
CMS2_k127_1641583_10 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 558.0
CMS2_k127_1641583_11 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 511.0
CMS2_k127_1641583_12 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 482.0
CMS2_k127_1641583_13 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 467.0
CMS2_k127_1641583_14 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 469.0
CMS2_k127_1641583_15 Toxic anion resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 453.0
CMS2_k127_1641583_16 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 451.0
CMS2_k127_1641583_17 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 454.0
CMS2_k127_1641583_18 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 441.0
CMS2_k127_1641583_19 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 421.0
CMS2_k127_1641583_2 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1347.0
CMS2_k127_1641583_20 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 381.0
CMS2_k127_1641583_21 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 385.0
CMS2_k127_1641583_22 formate dehydrogenase K00127 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 369.0
CMS2_k127_1641583_23 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 356.0
CMS2_k127_1641583_24 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 355.0
CMS2_k127_1641583_25 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 349.0
CMS2_k127_1641583_26 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 345.0
CMS2_k127_1641583_27 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 329.0
CMS2_k127_1641583_28 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 338.0
CMS2_k127_1641583_29 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 320.0
CMS2_k127_1641583_3 Monomeric isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1132.0
CMS2_k127_1641583_30 Aminotransferase, class I K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 312.0
CMS2_k127_1641583_31 ABC-type tungstate transport system K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 297.0
CMS2_k127_1641583_32 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 281.0
CMS2_k127_1641583_33 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000002142 267.0
CMS2_k127_1641583_34 membrane K08989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001247 251.0
CMS2_k127_1641583_35 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000155 250.0
CMS2_k127_1641583_36 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000001811 226.0
CMS2_k127_1641583_37 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000008006 219.0
CMS2_k127_1641583_38 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000005513 203.0
CMS2_k127_1641583_39 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000001349 192.0
CMS2_k127_1641583_4 GMC oxidoreductase K06151 - 1.1.99.3 4.242e-256 799.0
CMS2_k127_1641583_40 ABC transporter K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000002513 193.0
CMS2_k127_1641583_41 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000004794 188.0
CMS2_k127_1641583_42 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000000000002438 186.0
CMS2_k127_1641583_43 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000001045 166.0
CMS2_k127_1641583_44 Protein required for attachment to host cells - - - 0.0000000000000000000000000000000000000000007984 161.0
CMS2_k127_1641583_45 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000000000000000000000000000000000000001759 162.0
CMS2_k127_1641583_46 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000008044 154.0
CMS2_k127_1641583_47 Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000000000000000000001547 162.0
CMS2_k127_1641583_48 - - - - 0.00000000000000000000000000000000000004643 146.0
CMS2_k127_1641583_49 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000009827 134.0
CMS2_k127_1641583_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 2.666e-231 727.0
CMS2_k127_1641583_50 - - - - 0.00000000000000000000000000000001087 130.0
CMS2_k127_1641583_51 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000000001112 132.0
CMS2_k127_1641583_52 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000001198 127.0
CMS2_k127_1641583_55 protein conserved in bacteria K09937 - - 0.00000000001597 66.0
CMS2_k127_1641583_57 TIGRFAM formate dehydrogenase region TAT target - - - 0.0000001766 56.0
CMS2_k127_1641583_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 6.638e-219 685.0
CMS2_k127_1641583_7 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 5.495e-210 669.0
CMS2_k127_1641583_8 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.731e-201 633.0
CMS2_k127_1641583_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 625.0
CMS2_k127_166345_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.479e-208 655.0
CMS2_k127_166345_1 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 554.0
CMS2_k127_166345_2 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 448.0
CMS2_k127_166345_3 Mg2 transporter protein cora family protein K16074 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 349.0
CMS2_k127_166345_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 310.0
CMS2_k127_166345_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 329.0
CMS2_k127_166345_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 315.0
CMS2_k127_166345_7 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 295.0
CMS2_k127_166345_8 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.00000000000000000000000000000000000000000000000000006342 190.0
CMS2_k127_166345_9 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000001368 131.0
CMS2_k127_192154_0 PFAM von Willebrand factor type A - - - 0.0 1233.0
CMS2_k127_192154_1 PFAM AAA domain (dynein-related subfamily) K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 488.0
CMS2_k127_192154_2 Stress responsive A/B Barrel Domain K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 412.0
CMS2_k127_192154_3 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000001995 201.0
CMS2_k127_192154_4 - - - - 0.000000000000000000000000000000000000000000000007447 173.0
CMS2_k127_192154_5 - - - - 0.000000000000000002437 90.0
CMS2_k127_2017391_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 1.298e-270 853.0
CMS2_k127_2017391_1 ATPase (AAA K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 569.0
CMS2_k127_2017391_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 529.0
CMS2_k127_2017391_3 alanine dehydrogenase K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 349.0
CMS2_k127_2017391_4 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000001989 229.0
CMS2_k127_2017391_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000897 155.0
CMS2_k127_2055334_0 cofactor biosynthesis protein NifB K02585 - - 1.354e-265 823.0
CMS2_k127_2055334_1 Fis Family K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 452.0
CMS2_k127_2055334_2 PFAM NifQ K15790 - - 0.000000000000000000000000000000000000000000000000000003364 196.0
CMS2_k127_2055334_3 Ferredoxin - - - 0.0000000000000000000000000000000000000000000002147 168.0
CMS2_k127_2055334_4 Belongs to the ArsC family - - - 0.00000000000000000000000000000000000000000003284 164.0
CMS2_k127_2055334_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000006565 141.0
CMS2_k127_2076685_0 Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism K02567 - - 0.0 1495.0
CMS2_k127_2076685_1 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1220.0
CMS2_k127_2076685_10 reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 8.705e-220 683.0
CMS2_k127_2076685_100 Protein of unknown function (DUF2970) - - - 0.000000000004216 68.0
CMS2_k127_2076685_101 Protein of unknown function (DUF2909) - - - 0.00000000001306 66.0
CMS2_k127_2076685_102 Multicopper oxidase, type 3 - - - 0.0000000007917 71.0
CMS2_k127_2076685_103 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000001815 53.0
CMS2_k127_2076685_104 PFAM Type IV pilus assembly PilZ - - - 0.00006789 49.0
CMS2_k127_2076685_11 Zinc-binding dehydrogenase - - - 8.303e-215 671.0
CMS2_k127_2076685_12 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 604.0
CMS2_k127_2076685_13 associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 591.0
CMS2_k127_2076685_14 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 585.0
CMS2_k127_2076685_15 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 552.0
CMS2_k127_2076685_16 COG0348 Polyferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 541.0
CMS2_k127_2076685_17 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 531.0
CMS2_k127_2076685_18 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 503.0
CMS2_k127_2076685_19 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 497.0
CMS2_k127_2076685_2 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 3.928e-314 962.0
CMS2_k127_2076685_20 Putative metallopeptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 488.0
CMS2_k127_2076685_21 Quinol dehydrogenase K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 480.0
CMS2_k127_2076685_22 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 471.0
CMS2_k127_2076685_23 Na Pi-cotransporter family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 447.0
CMS2_k127_2076685_24 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 421.0
CMS2_k127_2076685_25 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 416.0
CMS2_k127_2076685_26 Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA K11391 - 2.1.1.174 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 398.0
CMS2_k127_2076685_27 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 371.0
CMS2_k127_2076685_28 Polycystin cation channel K08714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 366.0
CMS2_k127_2076685_29 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 356.0
CMS2_k127_2076685_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 5.258e-302 937.0
CMS2_k127_2076685_30 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 355.0
CMS2_k127_2076685_31 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 349.0
CMS2_k127_2076685_32 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 347.0
CMS2_k127_2076685_33 COG0784 FOG CheY-like receiver K20977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 357.0
CMS2_k127_2076685_34 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 345.0
CMS2_k127_2076685_35 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 326.0
CMS2_k127_2076685_36 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 330.0
CMS2_k127_2076685_37 COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit K02569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 323.0
CMS2_k127_2076685_38 Thioredoxin K03671,K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 321.0
CMS2_k127_2076685_39 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 325.0
CMS2_k127_2076685_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 1.019e-292 903.0
CMS2_k127_2076685_40 ABC-type transport system, involved in lipoprotein release, permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 317.0
CMS2_k127_2076685_41 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 312.0
CMS2_k127_2076685_42 protein required for cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 310.0
CMS2_k127_2076685_43 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 321.0
CMS2_k127_2076685_44 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 302.0
CMS2_k127_2076685_45 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 298.0
CMS2_k127_2076685_46 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 289.0
CMS2_k127_2076685_47 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 306.0
CMS2_k127_2076685_48 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001385 278.0
CMS2_k127_2076685_49 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008869 273.0
CMS2_k127_2076685_5 4Fe-4S dicluster domain - - - 2.578e-276 855.0
CMS2_k127_2076685_50 Ferredoxin-type protein napG of Proteobacteria UniRef RepID K02573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004589 268.0
CMS2_k127_2076685_51 response regulator receiver K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007752 269.0
CMS2_k127_2076685_52 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002549 267.0
CMS2_k127_2076685_53 PKHD-type hydroxylase K07336 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001568 262.0
CMS2_k127_2076685_54 4Fe-4S binding domain K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007887 254.0
CMS2_k127_2076685_55 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001912 240.0
CMS2_k127_2076685_56 TIGRFAM CRISPR-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000007729 236.0
CMS2_k127_2076685_57 Belongs to the DsrF TusC family K07236 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000000000000000000000000000000000000000000000000000000000000001055 220.0
CMS2_k127_2076685_59 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000001271 223.0
CMS2_k127_2076685_6 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.269e-267 834.0
CMS2_k127_2076685_60 Nitrite and sulphite reductase 4Fe-4S K02572 - - 0.000000000000000000000000000000000000000000000000000000000001535 215.0
CMS2_k127_2076685_61 TIGRFAM sulfur relay protein TusD DsrE K07235 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0019417,GO:0044237,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000002678 204.0
CMS2_k127_2076685_62 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.0000000000000000000000000000000000000000000000000000000004777 207.0
CMS2_k127_2076685_63 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000001008 205.0
CMS2_k127_2076685_64 - - - - 0.00000000000000000000000000000000000000000000000000000003352 211.0
CMS2_k127_2076685_65 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000000000000000001539 193.0
CMS2_k127_2076685_66 beta-lactamase activity K07126 - - 0.000000000000000000000000000000000000000000000000000401 187.0
CMS2_k127_2076685_67 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000005806 190.0
CMS2_k127_2076685_68 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000002242 175.0
CMS2_k127_2076685_69 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000004586 184.0
CMS2_k127_2076685_7 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 3.992e-239 742.0
CMS2_k127_2076685_70 response regulator receiver K02658 - - 0.000000000000000000000000000000000000000001808 158.0
CMS2_k127_2076685_71 SEC-C motif K09858 - - 0.000000000000000000000000000000000000002518 151.0
CMS2_k127_2076685_72 acetyltransferase K06323 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000002878 148.0
CMS2_k127_2076685_73 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000004072 152.0
CMS2_k127_2076685_74 - - - - 0.0000000000000000000000000000000000003495 147.0
CMS2_k127_2076685_75 cellulase activity - - - 0.00000000000000000000000000000000000154 154.0
CMS2_k127_2076685_76 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000001762 145.0
CMS2_k127_2076685_77 - - - - 0.000000000000000000000000000000000003038 147.0
CMS2_k127_2076685_78 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000003516 142.0
CMS2_k127_2076685_79 Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000000000000000008887 140.0
CMS2_k127_2076685_8 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 9.03e-228 726.0
CMS2_k127_2076685_80 Multicopper oxidase - - - 0.0000000000000000000000000000000003058 145.0
CMS2_k127_2076685_81 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000000000000000000000000000000003096 134.0
CMS2_k127_2076685_82 sulfur relay protein TusB DsrH K07237 - - 0.0000000000000000000000000000000009045 132.0
CMS2_k127_2076685_83 Sporulation related domain - - - 0.000000000000000000000000000000002206 136.0
CMS2_k127_2076685_84 Cyclic nucleotide-monophosphate binding domain K01420 - - 0.00000000000000000000000000000007091 134.0
CMS2_k127_2076685_85 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000001363 126.0
CMS2_k127_2076685_86 - - - - 0.00000000000000000000000000002296 124.0
CMS2_k127_2076685_87 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000003027 118.0
CMS2_k127_2076685_88 - - - - 0.00000000000000000000000006134 110.0
CMS2_k127_2076685_89 - - - - 0.0000000000000000000000002247 111.0
CMS2_k127_2076685_9 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 3.351e-226 710.0
CMS2_k127_2076685_90 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000003558 108.0
CMS2_k127_2076685_91 - - - - 0.000000000000000000000005083 105.0
CMS2_k127_2076685_92 - - - - 0.000000000000000000000188 108.0
CMS2_k127_2076685_93 - - - - 0.000000000000000000891 87.0
CMS2_k127_2076685_94 STAS domain K20978 - - 0.000000000000000005493 87.0
CMS2_k127_2076685_95 Putative prokaryotic signal transducing protein - - - 0.00000000000000002315 86.0
CMS2_k127_2076685_96 signal sequence binding - - - 0.00000000000000002596 89.0
CMS2_k127_2076685_97 Protein of unknown function (DUF503) K09764 - - 0.000000000000001973 79.0
CMS2_k127_2076685_99 - - - - 0.0000000000001022 73.0
CMS2_k127_2085814_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 1.367e-207 660.0
CMS2_k127_2085814_1 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009936 426.0
CMS2_k127_2085814_2 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 347.0
CMS2_k127_2085814_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000638 240.0
CMS2_k127_2085814_4 NMT1-like family - - - 0.0000000001079 63.0
CMS2_k127_208968_0 Pyridine nucleotide-disulphide oxidoreductase K00362,K05297 - 1.18.1.1,1.7.1.15 0.0 1250.0
CMS2_k127_208968_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1074.0
CMS2_k127_208968_10 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001721 282.0
CMS2_k127_208968_11 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.000000000000000000000000000000000000000000000000000000000000000000001722 241.0
CMS2_k127_208968_12 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.00000000000000000000000000000000000000000000000000000000000000000005892 235.0
CMS2_k127_208968_13 Peptidase membrane zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000000000000000007321 237.0
CMS2_k127_208968_14 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000001228 223.0
CMS2_k127_208968_15 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000000000000000000000000000000001481 216.0
CMS2_k127_208968_16 PFAM glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000000000000004465 201.0
CMS2_k127_208968_17 response regulator K07183 - - 0.00000000000000000000000000000000000000000000000000000231 197.0
CMS2_k127_208968_18 Long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000008596 172.0
CMS2_k127_208968_19 Nitrite reductase NAD(P)H , small subunit K00363 - 1.7.1.15 0.000000000000000000000000000000000000000000003706 166.0
CMS2_k127_208968_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576 - - 7.8e-256 793.0
CMS2_k127_208968_21 Thioesterase superfamily K10806 - - 0.000000000000000000000000000000000000000009226 157.0
CMS2_k127_208968_22 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000004763 154.0
CMS2_k127_208968_23 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000001682 156.0
CMS2_k127_208968_24 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000002878 148.0
CMS2_k127_208968_25 Part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000004065 143.0
CMS2_k127_208968_26 Xylose isomerase domain protein TIM barrel K09930 - - 0.00000000000000000000000000000000131 132.0
CMS2_k127_208968_27 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000002074 103.0
CMS2_k127_208968_28 (Hpt) domain - - - 0.00002156 51.0
CMS2_k127_208968_3 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 1.075e-231 732.0
CMS2_k127_208968_4 Glycosyltransferase - - - 8.427e-211 660.0
CMS2_k127_208968_5 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 450.0
CMS2_k127_208968_6 NMT1-like family K15576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 439.0
CMS2_k127_208968_7 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 434.0
CMS2_k127_208968_8 Transcriptional regulator K13634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 336.0
CMS2_k127_208968_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 335.0
CMS2_k127_2098209_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 431.0
CMS2_k127_2098209_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 308.0
CMS2_k127_2098209_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000008416 251.0
CMS2_k127_2098209_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.000000000000000000000000000267 125.0
CMS2_k127_2098209_4 STAS domain - - - 0.000003122 55.0
CMS2_k127_2098209_6 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0002061 44.0
CMS2_k127_2128634_0 RNA polymerase recycling family C-terminal K03580 - - 0.0 1047.0
CMS2_k127_2128634_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 5e-324 1013.0
CMS2_k127_2128634_10 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 511.0
CMS2_k127_2128634_11 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 495.0
CMS2_k127_2128634_12 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 481.0
CMS2_k127_2128634_13 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008678 456.0
CMS2_k127_2128634_14 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 389.0
CMS2_k127_2128634_15 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 376.0
CMS2_k127_2128634_16 PFAM Dual specificity protein phosphatase K14165 - 3.1.3.16,3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 354.0
CMS2_k127_2128634_17 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 343.0
CMS2_k127_2128634_18 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 342.0
CMS2_k127_2128634_19 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 301.0
CMS2_k127_2128634_2 Cytochrome c-type biogenesis protein CcmF K02198 - - 8.416e-275 859.0
CMS2_k127_2128634_20 Bacterial-like globin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 316.0
CMS2_k127_2128634_21 Bacterial protein of unknown function (DUF898) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007239 275.0
CMS2_k127_2128634_22 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 266.0
CMS2_k127_2128634_23 GTP-binding domain protein K06945 - - 0.000000000000000000000000000000000000000000000000000000000000000000004748 238.0
CMS2_k127_2128634_24 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001944 246.0
CMS2_k127_2128634_25 Tetratricopeptide repeat K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000001145 246.0
CMS2_k127_2128634_26 TIGRFAM periplasmic protein thiol K02199 - - 0.000000000000000000000000000000000000000000000000000000000005148 212.0
CMS2_k127_2128634_27 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000107 207.0
CMS2_k127_2128634_28 transcription factor binding - - - 0.000000000000000000000000000000000000000000000000000007593 192.0
CMS2_k127_2128634_29 - K09004 - - 0.000000000000000000000000000000000000000000000000001619 186.0
CMS2_k127_2128634_3 pfam abc - - - 3.957e-269 836.0
CMS2_k127_2128634_30 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000000000000000001624 194.0
CMS2_k127_2128634_31 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000003042 179.0
CMS2_k127_2128634_32 subfamily IA, variant 1 K20862 - 3.1.3.102,3.1.3.104 0.000000000000000000000000000000000000000000000001451 182.0
CMS2_k127_2128634_33 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000000000000000000000000003467 175.0
CMS2_k127_2128634_34 COG1186 Protein chain release factor B K15034 - - 0.0000000000000000000000000000000000000000000003155 170.0
CMS2_k127_2128634_35 Belongs to the ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.00000000000000000000000000000000000006661 145.0
CMS2_k127_2128634_36 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000002585 142.0
CMS2_k127_2128634_37 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000437 142.0
CMS2_k127_2128634_38 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000008819 133.0
CMS2_k127_2128634_39 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000003627 138.0
CMS2_k127_2128634_4 diguanylate cyclase - - - 3.497e-244 776.0
CMS2_k127_2128634_40 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000000000137 133.0
CMS2_k127_2128634_41 Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000000003459 126.0
CMS2_k127_2128634_42 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000006067 113.0
CMS2_k127_2128634_43 Endonuclease containing a URI domain K07461 - - 0.0000000000000000000000003264 107.0
CMS2_k127_2128634_44 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000001878 103.0
CMS2_k127_2128634_45 Roadblock/LC7 domain K07131 - - 0.0000000000000000000008324 100.0
CMS2_k127_2128634_46 - - - - 0.00000000000000001105 84.0
CMS2_k127_2128634_47 Fe-S protein - - - 0.0000000000001077 73.0
CMS2_k127_2128634_48 - - - - 0.0000000000001164 79.0
CMS2_k127_2128634_49 Tetratricopeptide repeat - - - 0.0000000000001768 80.0
CMS2_k127_2128634_5 Belongs to the DEAD box helicase family K05591 GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 5.673e-205 646.0
CMS2_k127_2128634_50 Putative zinc- or iron-chelating domain - - - 0.0000000004952 65.0
CMS2_k127_2128634_52 - - - - 0.00001109 55.0
CMS2_k127_2128634_53 - - - - 0.00001418 50.0
CMS2_k127_2128634_54 Protein of unknown function (DUF2621) - - - 0.00004038 53.0
CMS2_k127_2128634_6 Succinyldiaminopimelate K14261,K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 564.0
CMS2_k127_2128634_7 von willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 561.0
CMS2_k127_2128634_8 COG2925 Exonuclease I K01141 GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 555.0
CMS2_k127_2128634_9 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 512.0
CMS2_k127_2205763_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001557 270.0
CMS2_k127_2205763_1 PFAM TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000003241 239.0
CMS2_k127_2205763_2 Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000003288 205.0
CMS2_k127_2219617_0 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 1.63e-213 669.0
CMS2_k127_2219617_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 611.0
CMS2_k127_2219617_10 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004061 263.0
CMS2_k127_2219617_11 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004977 245.0
CMS2_k127_2219617_12 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000004433 223.0
CMS2_k127_2219617_13 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000004672 227.0
CMS2_k127_2219617_14 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.00000000000000000000000000000000000000000000000000000000000007606 218.0
CMS2_k127_2219617_15 COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000001122 217.0
CMS2_k127_2219617_16 - - - - 0.00000000000006756 78.0
CMS2_k127_2219617_2 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 600.0
CMS2_k127_2219617_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 591.0
CMS2_k127_2219617_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 422.0
CMS2_k127_2219617_5 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 409.0
CMS2_k127_2219617_6 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 397.0
CMS2_k127_2219617_7 Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) K06957 GO:0000049,GO:0000154,GO:0002097,GO:0002101,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0022613,GO:0030490,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0051391,GO:0051392,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1904812,GO:1990882,GO:1990883,GO:1990884 2.3.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 366.0
CMS2_k127_2219617_8 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 293.0
CMS2_k127_2219617_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 294.0
CMS2_k127_2222517_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 588.0
CMS2_k127_2222517_1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ K11910 - - 0.00000000000000000000000000000000000000000000000000000000003917 224.0
CMS2_k127_2222517_2 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000001276 209.0
CMS2_k127_224410_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 592.0
CMS2_k127_224410_1 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002666 237.0
CMS2_k127_224410_2 STAS domain - - - 0.0005553 49.0
CMS2_k127_2268214_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1034.0
CMS2_k127_2268214_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 2.787e-201 635.0
CMS2_k127_2268214_10 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 484.0
CMS2_k127_2268214_11 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 475.0
CMS2_k127_2268214_12 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 465.0
CMS2_k127_2268214_13 unusual protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 466.0
CMS2_k127_2268214_14 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 441.0
CMS2_k127_2268214_15 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 424.0
CMS2_k127_2268214_16 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 433.0
CMS2_k127_2268214_17 Domain of unknown function (DUF3391) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 411.0
CMS2_k127_2268214_18 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 387.0
CMS2_k127_2268214_19 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 375.0
CMS2_k127_2268214_2 PFAM malic K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 600.0
CMS2_k127_2268214_20 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 356.0
CMS2_k127_2268214_21 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 356.0
CMS2_k127_2268214_22 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 353.0
CMS2_k127_2268214_23 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 334.0
CMS2_k127_2268214_24 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 341.0
CMS2_k127_2268214_25 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 325.0
CMS2_k127_2268214_26 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 319.0
CMS2_k127_2268214_27 transport system, permease component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 305.0
CMS2_k127_2268214_28 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 307.0
CMS2_k127_2268214_29 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 295.0
CMS2_k127_2268214_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 580.0
CMS2_k127_2268214_30 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 300.0
CMS2_k127_2268214_31 COG0258 5'-3' exonuclease (including N-terminal domain of PolI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 297.0
CMS2_k127_2268214_32 PFAM Peptidoglycan-binding lysin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 301.0
CMS2_k127_2268214_33 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000007126 263.0
CMS2_k127_2268214_34 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000004908 245.0
CMS2_k127_2268214_35 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000002416 241.0
CMS2_k127_2268214_36 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000000000917 243.0
CMS2_k127_2268214_37 His Kinase A (phosphoacceptor) domain K07678,K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001243 258.0
CMS2_k127_2268214_38 Bacterial transferase hexapeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000003394 227.0
CMS2_k127_2268214_39 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000003759 205.0
CMS2_k127_2268214_4 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 561.0
CMS2_k127_2268214_40 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000001769 186.0
CMS2_k127_2268214_41 COG0725 ABC-type molybdate transport system, periplasmic component K02020 - - 0.0000000000000000000000000000000000000000000000001204 186.0
CMS2_k127_2268214_42 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061710,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000008325 171.0
CMS2_k127_2268214_43 Phosphoribosyl-ATP pyrophosphohydrolase - - - 0.000000000000000000000000000000000000000000196 160.0
CMS2_k127_2268214_44 Competence protein - GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000001046 166.0
CMS2_k127_2268214_45 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000005728 156.0
CMS2_k127_2268214_46 - - - - 0.000000000000000000000000000000000000005149 151.0
CMS2_k127_2268214_47 type III effector - - - 0.0000000000000000000000000000000000003396 143.0
CMS2_k127_2268214_48 PFAM Bacterial regulatory protein, arsR family K03892 - - 0.000000000000000000000000000000000505 134.0
CMS2_k127_2268214_49 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000007841 130.0
CMS2_k127_2268214_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 559.0
CMS2_k127_2268214_50 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000001088 118.0
CMS2_k127_2268214_51 WDYHV motif containing 1 K21286 GO:0003008,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008150,GO:0008152,GO:0008306,GO:0008355,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0030163,GO:0032501,GO:0036211,GO:0042048,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050877,GO:0050890,GO:0050896,GO:0070773,GO:0071704,GO:1901564,GO:1901565,GO:1901575 3.5.1.122 0.0000000000000000000000000001397 122.0
CMS2_k127_2268214_52 Staphylococcal nuclease homologues - - - 0.0000000000000000000000000003444 126.0
CMS2_k127_2268214_53 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000002815 111.0
CMS2_k127_2268214_54 - - - - 0.000000000000000000000000526 108.0
CMS2_k127_2268214_55 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000832 98.0
CMS2_k127_2268214_56 Domain of unknown function (DUF4124) - - - 0.00000000000000000009916 98.0
CMS2_k127_2268214_57 Domain of unknown function (DUF4266) - - - 0.000000000000000000512 90.0
CMS2_k127_2268214_59 PilZ domain - - - 0.00000000005342 68.0
CMS2_k127_2268214_6 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 535.0
CMS2_k127_2268214_60 - - - - 0.0000006359 56.0
CMS2_k127_2268214_62 Signal transduction protein - - - 0.0000302 55.0
CMS2_k127_2268214_63 PilZ domain - - - 0.0003354 48.0
CMS2_k127_2268214_7 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 541.0
CMS2_k127_2268214_8 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 511.0
CMS2_k127_2268214_9 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 509.0
CMS2_k127_2293549_0 helicase superfamily c-terminal domain - - - 1.333e-201 632.0
CMS2_k127_2293549_1 2-Nitropropane dioxygenase K00459 - 1.13.12.16 2.989e-198 626.0
CMS2_k127_2293549_10 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000000000000002699 192.0
CMS2_k127_2293549_11 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000001782 169.0
CMS2_k127_2293549_12 Protein of unknown function (DUF3087) - - - 0.000000000000000000000000000000000000000439 154.0
CMS2_k127_2293549_13 small membrane protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000001708 127.0
CMS2_k127_2293549_15 - - - - 0.00000000000000000000000007406 111.0
CMS2_k127_2293549_16 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000008298 108.0
CMS2_k127_2293549_17 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family - - - 0.000000000000000000001222 96.0
CMS2_k127_2293549_18 PEP-CTERM motif - - - 0.000000000000000000019 100.0
CMS2_k127_2293549_2 metal-dependent protein hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 531.0
CMS2_k127_2293549_20 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.00000000000000000758 87.0
CMS2_k127_2293549_21 Uncharacterised protein family (UPF0160) - - - 0.0000000000009751 69.0
CMS2_k127_2293549_22 YeeE YedE family protein K07112 - - 0.000000006911 68.0
CMS2_k127_2293549_23 PCO_ADO K10712 - 1.13.11.19 0.000000249 61.0
CMS2_k127_2293549_25 - - - - 0.000002657 52.0
CMS2_k127_2293549_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 393.0
CMS2_k127_2293549_4 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 306.0
CMS2_k127_2293549_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 302.0
CMS2_k127_2293549_6 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000106 265.0
CMS2_k127_2293549_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001854 242.0
CMS2_k127_2293549_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000006797 245.0
CMS2_k127_2293549_9 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000000000000000002249 191.0
CMS2_k127_2311383_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 1.233e-234 738.0
CMS2_k127_2311383_1 Belongs to the RimK family K05844 - - 3.472e-227 711.0
CMS2_k127_2311383_2 Response regulator receiver K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 493.0
CMS2_k127_2311383_3 RNA-metabolising metallo-beta-lactamase K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 477.0
CMS2_k127_2311383_4 PFAM AhpC TSA family - - - 0.000000000000000000000000000000000000000000000000000000000000000001662 234.0
CMS2_k127_2311383_5 - - - - 0.000000000000000004824 86.0
CMS2_k127_2311383_6 Cysteine-rich CWC - - - 0.0000000004555 64.0
CMS2_k127_2430645_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1255.0
CMS2_k127_2430645_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 8.606e-316 975.0
CMS2_k127_2430645_10 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 585.0
CMS2_k127_2430645_11 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 553.0
CMS2_k127_2430645_12 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 550.0
CMS2_k127_2430645_13 transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 519.0
CMS2_k127_2430645_14 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 520.0
CMS2_k127_2430645_15 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 518.0
CMS2_k127_2430645_16 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 503.0
CMS2_k127_2430645_17 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 503.0
CMS2_k127_2430645_18 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 467.0
CMS2_k127_2430645_19 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 424.0
CMS2_k127_2430645_2 5'-nucleotidase, C-terminal domain K17224 - - 7.372e-300 931.0
CMS2_k127_2430645_20 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 421.0
CMS2_k127_2430645_21 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 379.0
CMS2_k127_2430645_22 COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit K00240 GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 369.0
CMS2_k127_2430645_23 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772,K19696 - 2.4.2.28,2.4.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 325.0
CMS2_k127_2430645_24 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 325.0
CMS2_k127_2430645_25 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 329.0
CMS2_k127_2430645_26 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 303.0
CMS2_k127_2430645_27 Hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
CMS2_k127_2430645_28 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 297.0
CMS2_k127_2430645_29 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 293.0
CMS2_k127_2430645_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.23e-274 853.0
CMS2_k127_2430645_30 Protein of unknown function (DUF455) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 295.0
CMS2_k127_2430645_31 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 289.0
CMS2_k127_2430645_32 TRAP dicarboxylate transporter, DctQ subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 287.0
CMS2_k127_2430645_33 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 288.0
CMS2_k127_2430645_34 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 285.0
CMS2_k127_2430645_35 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000271 282.0
CMS2_k127_2430645_36 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005853 284.0
CMS2_k127_2430645_37 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003489 255.0
CMS2_k127_2430645_38 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000006514 246.0
CMS2_k127_2430645_39 Response regulator receiver K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000003194 235.0
CMS2_k127_2430645_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 1.798e-257 801.0
CMS2_k127_2430645_40 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.0000000000000000000000000000000000000000000000000000000000000001254 225.0
CMS2_k127_2430645_41 Signal transduction protein K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000002732 226.0
CMS2_k127_2430645_42 protein conserved in bacteria K09928 - - 0.00000000000000000000000000000000000000000000000000000000000001782 218.0
CMS2_k127_2430645_43 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000005734 221.0
CMS2_k127_2430645_44 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000000000001532 219.0
CMS2_k127_2430645_45 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000001062 208.0
CMS2_k127_2430645_46 High frequency lysogenization protein HflD homolog K07153 - - 0.00000000000000000000000000000000000000000000000000174 189.0
CMS2_k127_2430645_47 Conserved hypothetical ATP binding protein K06945 - - 0.00000000000000000000000000000000000000000000000001757 185.0
CMS2_k127_2430645_48 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000001038 164.0
CMS2_k127_2430645_49 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000004637 162.0
CMS2_k127_2430645_5 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 8.092e-250 776.0
CMS2_k127_2430645_50 COG0848 Biopolymer transport protein K03559 - - 0.000000000000000000000000000000000001081 143.0
CMS2_k127_2430645_51 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000003941 133.0
CMS2_k127_2430645_52 PFAM Appr-1-p processing domain protein - - - 0.000000000000000000000000000000004711 136.0
CMS2_k127_2430645_53 Protein of unknown function (DUF1249) K09920 - - 0.0000000000000000000000000000006908 128.0
CMS2_k127_2430645_54 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000000007162 105.0
CMS2_k127_2430645_55 Belongs to the Rsd AlgQ family K07740 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0000000000000000000000219 106.0
CMS2_k127_2430645_56 succinate dehydrogenase activity K00242 GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017004,GO:0017144,GO:0019752,GO:0020037,GO:0022607,GO:0022900,GO:0032991,GO:0034622,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0065003,GO:0070469,GO:0070470,GO:0071704,GO:0071840,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 - 0.0000000000000000001096 93.0
CMS2_k127_2430645_57 - - - - 0.0000000000000000001479 98.0
CMS2_k127_2430645_58 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000001362 88.0
CMS2_k127_2430645_59 Belongs to the UPF0434 family K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000121 83.0
CMS2_k127_2430645_6 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.439e-221 692.0
CMS2_k127_2430645_60 Invasion gene expression up-regulator, SirB - - - 0.0000000000000003506 83.0
CMS2_k127_2430645_61 membrane-bound metal-dependent K07038 - - 0.0000000000000004083 89.0
CMS2_k127_2430645_62 - - - - 0.0000000000000007474 89.0
CMS2_k127_2430645_63 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000007078 77.0
CMS2_k127_2430645_64 Competence protein ComEA K02237 - - 0.00000000000004481 75.0
CMS2_k127_2430645_65 protein acetylation - - - 0.000000000000549 76.0
CMS2_k127_2430645_66 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.0000000002355 71.0
CMS2_k127_2430645_7 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 1.588e-212 681.0
CMS2_k127_2430645_8 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 1.06e-206 650.0
CMS2_k127_2430645_9 GAF domain - - - 1.226e-194 621.0
CMS2_k127_2470867_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 2.234e-206 652.0
CMS2_k127_2470867_1 PFAM TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 606.0
CMS2_k127_2470867_10 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 327.0
CMS2_k127_2470867_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 313.0
CMS2_k127_2470867_12 Diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 296.0
CMS2_k127_2470867_13 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009419 282.0
CMS2_k127_2470867_14 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009569 276.0
CMS2_k127_2470867_15 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003383 250.0
CMS2_k127_2470867_16 Protein of unknown function (DUF1456) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007904 246.0
CMS2_k127_2470867_17 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02560 - 2.3.1.243 0.000000000000000000000000000000000000000000000000000000000001153 221.0
CMS2_k127_2470867_18 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000001421 208.0
CMS2_k127_2470867_19 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000005053 203.0
CMS2_k127_2470867_2 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 476.0
CMS2_k127_2470867_20 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000001958 188.0
CMS2_k127_2470867_21 PFAM phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000000000000000001307 167.0
CMS2_k127_2470867_22 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000000000000006433 157.0
CMS2_k127_2470867_23 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000003205 142.0
CMS2_k127_2470867_24 Domain of unknown function (DUF4381) - - - 0.0000000000000000000000002932 112.0
CMS2_k127_2470867_25 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000003545 99.0
CMS2_k127_2470867_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705 - 0.00000000000000002466 84.0
CMS2_k127_2470867_27 von Willebrand factor, type A K07114 - - 0.00000000502 59.0
CMS2_k127_2470867_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 459.0
CMS2_k127_2470867_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 436.0
CMS2_k127_2470867_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814,K01817 - 5.3.1.16,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 393.0
CMS2_k127_2470867_6 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 389.0
CMS2_k127_2470867_7 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 362.0
CMS2_k127_2470867_8 PFAM DegT DnrJ EryC1 StrS aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 362.0
CMS2_k127_2470867_9 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 336.0
CMS2_k127_2519664_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.799e-236 736.0
CMS2_k127_2519664_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 419.0
CMS2_k127_2519664_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 304.0
CMS2_k127_2519664_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000002667 183.0
CMS2_k127_2519664_4 epsilon subunit K02114 - - 0.0000000000000000000000000000000000000000005369 161.0
CMS2_k127_2519664_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000001005 154.0
CMS2_k127_2519664_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000004796 138.0
CMS2_k127_2519664_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000000000000000000000000004074 129.0
CMS2_k127_252556_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 531.0
CMS2_k127_252556_1 Glycosyl transferases group 1 K21001 - - 0.00000000000000000000000000000000000000000000000000000000000006282 222.0
CMS2_k127_252556_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000001316 156.0
CMS2_k127_25753_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.669e-233 745.0
CMS2_k127_25753_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 413.0
CMS2_k127_25753_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 305.0
CMS2_k127_25753_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 298.0
CMS2_k127_25753_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000102 215.0
CMS2_k127_25753_5 protein conserved in bacteria K11022 - - 0.00000000000000000000000000000000000000000004588 162.0
CMS2_k127_25753_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000001589 105.0
CMS2_k127_25753_7 PFAM Outer membrane K06142 - - 0.000000000000000000003819 100.0
CMS2_k127_258999_0 ABC transporter K15738 - - 3.795e-218 694.0
CMS2_k127_258999_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 424.0
CMS2_k127_258999_10 Specifically methylates the guanosine in position 1516 of 16S rRNA K15984 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.242 0.0000000000000000000000000000000000000000000000003079 185.0
CMS2_k127_258999_11 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000002614 130.0
CMS2_k127_258999_12 Belongs to the BolA IbaG family - - - 0.0000000000000000000009112 96.0
CMS2_k127_258999_13 Protein of unknown function (DUF2835) - - - 0.000000000000001142 78.0
CMS2_k127_258999_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 400.0
CMS2_k127_258999_3 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 363.0
CMS2_k127_258999_4 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 310.0
CMS2_k127_258999_5 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002095 259.0
CMS2_k127_258999_6 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002784 255.0
CMS2_k127_258999_7 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000000000000000000000000000000000003283 227.0
CMS2_k127_258999_8 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000000000000000000000006199 214.0
CMS2_k127_258999_9 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000001493 192.0
CMS2_k127_2656891_0 diguanylate cyclase - - - 0.000000000000000000000000000000000004726 154.0
CMS2_k127_2698169_0 Acyltransferase - - - 4.528e-222 705.0
CMS2_k127_2698169_1 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008988 282.0
CMS2_k127_2698169_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003314 267.0
CMS2_k127_2698169_3 Sporulation related domain - - - 0.000000000000000000000000000000000003856 144.0
CMS2_k127_282286_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 601.0
CMS2_k127_282286_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 335.0
CMS2_k127_282286_2 COG0501 Zn-dependent protease with chaperone function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 316.0
CMS2_k127_282286_3 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 293.0
CMS2_k127_282286_4 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000001901 164.0
CMS2_k127_282286_5 Fe-S-cluster oxidoreductase - - - 0.000000000000000000000000000000000000001136 149.0
CMS2_k127_2912943_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0 1005.0
CMS2_k127_2912943_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 485.0
CMS2_k127_2912943_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 312.0
CMS2_k127_2912943_3 Universal stress protein K06149 - - 0.000000000000000000000000000000038 129.0
CMS2_k127_3087232_0 Atp-dependent helicase K03579 - 3.6.4.13 9.996e-200 628.0
CMS2_k127_3087232_1 mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 417.0
CMS2_k127_3087232_10 Protein of unknown function (DUF504) - - - 0.00000000000000000002426 93.0
CMS2_k127_3087232_11 Tfp pilus assembly protein FimV - - - 0.00000000000000000005924 104.0
CMS2_k127_3087232_12 Protein of unknown function (DUF3135) - - - 0.00000000002121 70.0
CMS2_k127_3087232_15 acetyltransferase K01091 - 3.1.3.18 0.0000029 58.0
CMS2_k127_3087232_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 364.0
CMS2_k127_3087232_3 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 330.0
CMS2_k127_3087232_4 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003967 256.0
CMS2_k127_3087232_5 HD domain K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000001456 234.0
CMS2_k127_3087232_6 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000002015 214.0
CMS2_k127_3087232_7 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000000004697 170.0
CMS2_k127_3087232_8 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000000000003143 133.0
CMS2_k127_3087232_9 Thioredoxin - - - 0.000000000000000000000000006893 113.0
CMS2_k127_3115727_0 GAF domain K20962 - 3.1.4.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 335.0
CMS2_k127_3115727_1 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000369 296.0
CMS2_k127_3115727_2 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001076 274.0
CMS2_k127_3115727_3 Thioredoxin-like - - - 0.000000000000000000000000000000000000004454 151.0
CMS2_k127_3115727_4 Domain of unknown function (DUF4266) - - - 0.000000000000000000002608 94.0
CMS2_k127_3124283_0 Domain of unknown function (DUF3492) K21011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 455.0
CMS2_k127_3124283_1 Putative exopolysaccharide Exporter (EPS-E) K21012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 432.0
CMS2_k127_3124283_2 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 416.0
CMS2_k127_3124283_3 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 390.0
CMS2_k127_3124283_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003425 280.0
CMS2_k127_3124283_5 Gaf domain K02584,K07713,K11908,K12266,K15836,K21009,K21405 - - 0.0000000000000000000000000000000000000000000000000000000000003267 223.0
CMS2_k127_3124283_6 peptidyl-tyrosine sulfation K21010 - - 0.0000000000000000000000000000009923 135.0
CMS2_k127_3140706_0 chemotaxis K02660 - - 4.413e-204 655.0
CMS2_k127_3140706_1 response regulator receiver K02487,K06596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 354.0
CMS2_k127_3140706_2 response regulator receiver K02657 - - 0.00000000000000000000000000000000000000000000000000000000000008778 214.0
CMS2_k127_3140706_3 Belongs to the prokaryotic GSH synthase family K01920 GO:0000287,GO:0003674,GO:0003824,GO:0004363,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.000000000000000000000000000000000000000000000003974 175.0
CMS2_k127_3140706_4 response regulator receiver K02658 - - 0.0000000000000000000000000000000000000000000001318 170.0
CMS2_k127_3140706_5 Two component signalling adaptor domain K02659 - - 0.000000000000000000000000000000000000000001588 162.0
CMS2_k127_3197319_0 PFAM TM1410 hypothetical-related protein K21006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 620.0
CMS2_k127_3197319_1 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 628.0
CMS2_k127_3197319_2 Glycoside-hydrolase family GH114 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 297.0
CMS2_k127_3197319_3 Glycoside-hydrolase family GH114 K21006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003704 273.0
CMS2_k127_3197319_4 self proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000000000000006494 262.0
CMS2_k127_3197319_5 chaperone-mediated protein folding K11935 - - 0.00000000000000000000000000000000000000000000000000000000000000007458 249.0
CMS2_k127_3197319_6 domain, Protein K01674,K03646 - 4.2.1.1 0.0000000000000000000000000001652 131.0
CMS2_k127_3197319_7 polysaccharide catabolic process K01176,K01179 - 3.2.1.1,3.2.1.4 0.0000000000000000008798 103.0
CMS2_k127_3214563_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 1.171e-271 837.0
CMS2_k127_3214563_1 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 376.0
CMS2_k127_3214563_2 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000008623 216.0
CMS2_k127_3214563_3 - - - - 0.00000000000000000000000000000000000000000000000000000003767 198.0
CMS2_k127_3253472_0 FAD linked - - - 0.0 1673.0
CMS2_k127_3253472_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 445.0
CMS2_k127_3253472_10 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000004385 201.0
CMS2_k127_3253472_11 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000001534 182.0
CMS2_k127_3253472_12 Ferredoxin - - - 0.0000000000000000000000000000000000000007192 150.0
CMS2_k127_3253472_13 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.00000000000000000000000000000005135 125.0
CMS2_k127_3253472_14 Gram-negative porin - - - 0.000000000000001067 88.0
CMS2_k127_3253472_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 425.0
CMS2_k127_3253472_3 Pyruvate kinase, alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 419.0
CMS2_k127_3253472_4 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 409.0
CMS2_k127_3253472_5 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001452 265.0
CMS2_k127_3253472_6 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006023 257.0
CMS2_k127_3253472_7 4Fe-4S double cluster binding domain K11473,K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002305 261.0
CMS2_k127_3253472_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000009351 239.0
CMS2_k127_3253472_9 PFAM OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000002706 226.0
CMS2_k127_3294875_0 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001036 277.0
CMS2_k127_3294875_1 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006868 260.0
CMS2_k127_3294875_2 Type VI secretion system (T6SS), amidase effector protein 4 - - - 0.000000000000000000000000000000000000000000000000000000001151 205.0
CMS2_k127_3294875_3 PFAM HPP family K07168 - - 0.00000000000000000000000000000000000000000000000000000005762 200.0
CMS2_k127_3294875_4 - - - - 0.000000000000000000000000000000000000000000000000005255 184.0
CMS2_k127_3294875_5 Group 1 truncated hemoglobin K06886 - - 0.00000000000000000000000000000000000000000000008817 173.0
CMS2_k127_3294875_6 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000001317 171.0
CMS2_k127_3294875_7 transcriptional regulator K13771 - - 0.0000000000000000000000000000000000001224 146.0
CMS2_k127_3294875_8 Transposase K07491 - - 0.000000008071 56.0
CMS2_k127_3307815_0 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 449.0
CMS2_k127_3307815_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0000000000000004081 78.0
CMS2_k127_3320167_0 Diguanylate cyclase - - - 1.447e-203 658.0
CMS2_k127_3320167_1 RmlD substrate binding domain K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 313.0
CMS2_k127_3320167_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000003171 243.0
CMS2_k127_3320167_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000009444 81.0
CMS2_k127_3361909_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.614e-269 835.0
CMS2_k127_3361909_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.974e-253 786.0
CMS2_k127_3361909_10 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 367.0
CMS2_k127_3361909_11 type II secretion K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 346.0
CMS2_k127_3361909_12 Lipase (class 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 332.0
CMS2_k127_3361909_13 PFAM Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001688 254.0
CMS2_k127_3361909_14 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000008315 222.0
CMS2_k127_3361909_15 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000001459 214.0
CMS2_k127_3361909_16 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000008295 190.0
CMS2_k127_3361909_17 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000001865 186.0
CMS2_k127_3361909_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000001416 183.0
CMS2_k127_3361909_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000002355 181.0
CMS2_k127_3361909_2 type II secretion system protein E K02454,K02652,K12276 - - 1.185e-214 681.0
CMS2_k127_3361909_20 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000003329 179.0
CMS2_k127_3361909_21 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000000000007484 177.0
CMS2_k127_3361909_22 - - - - 0.000000000000000000000000000000000000000001626 161.0
CMS2_k127_3361909_23 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000002552 151.0
CMS2_k127_3361909_24 ATP synthase subunit C K02110 - - 0.0000000000000000000000000000000005403 131.0
CMS2_k127_3361909_25 - - - - 0.00000000000000000000000000006156 132.0
CMS2_k127_3361909_26 Tetratricopeptide repeats - - - 0.000000000000000000000000005096 125.0
CMS2_k127_3361909_28 - - - - 0.0000000000002365 78.0
CMS2_k127_3361909_29 ATP synthase I chain K02116 - - 0.0000000028 63.0
CMS2_k127_3361909_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 537.0
CMS2_k127_3361909_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 522.0
CMS2_k127_3361909_5 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 491.0
CMS2_k127_3361909_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 407.0
CMS2_k127_3361909_7 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 400.0
CMS2_k127_3361909_8 Lipase (class 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 398.0
CMS2_k127_3361909_9 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 376.0
CMS2_k127_3361974_0 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 402.0
CMS2_k127_3361974_1 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 337.0
CMS2_k127_3361974_2 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 291.0
CMS2_k127_3361974_3 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000001034 216.0
CMS2_k127_3361974_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 0.0000000000000000000000000000000000000000000004992 168.0
CMS2_k127_3393092_0 Ammonium Transporter K03320 - - 4.469e-225 702.0
CMS2_k127_3393092_1 COG0642 Signal transduction histidine kinase K20974 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 616.0
CMS2_k127_3393092_2 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000000006274 206.0
CMS2_k127_3393092_3 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000563 60.0
CMS2_k127_3430445_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1659.0
CMS2_k127_3430445_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 5.795e-318 986.0
CMS2_k127_3430445_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 4.833e-249 772.0
CMS2_k127_3430445_100 - - - - 0.00000005275 54.0
CMS2_k127_3430445_101 Domain of unknown function (DUF4845) - - - 0.0000002339 57.0
CMS2_k127_3430445_102 PFAM glutaredoxin 2 - - - 0.0000004751 54.0
CMS2_k127_3430445_103 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E K03597 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0000009202 58.0
CMS2_k127_3430445_105 bacterial-type flagellum organization K02398 - - 0.00001926 51.0
CMS2_k127_3430445_107 DnaJ molecular chaperone homology domain - - - 0.00062 50.0
CMS2_k127_3430445_11 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.197e-247 773.0
CMS2_k127_3430445_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 4.277e-247 766.0
CMS2_k127_3430445_13 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.479e-242 757.0
CMS2_k127_3430445_14 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.567e-240 750.0
CMS2_k127_3430445_15 Participates in both transcription termination and antitermination K02600 - - 1.378e-223 702.0
CMS2_k127_3430445_16 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 3.024e-207 651.0
CMS2_k127_3430445_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 603.0
CMS2_k127_3430445_18 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 592.0
CMS2_k127_3430445_19 Belongs to the CarA family K01956 GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 572.0
CMS2_k127_3430445_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.157e-306 950.0
CMS2_k127_3430445_20 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 564.0
CMS2_k127_3430445_21 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009871 548.0
CMS2_k127_3430445_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 520.0
CMS2_k127_3430445_23 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 513.0
CMS2_k127_3430445_24 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007131 479.0
CMS2_k127_3430445_25 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 470.0
CMS2_k127_3430445_26 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 466.0
CMS2_k127_3430445_27 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 443.0
CMS2_k127_3430445_28 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 437.0
CMS2_k127_3430445_29 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 424.0
CMS2_k127_3430445_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.895e-296 921.0
CMS2_k127_3430445_30 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 438.0
CMS2_k127_3430445_31 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 394.0
CMS2_k127_3430445_32 Chemotaxis protein K03415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 381.0
CMS2_k127_3430445_33 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 377.0
CMS2_k127_3430445_34 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 374.0
CMS2_k127_3430445_35 basal body rod protein K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 371.0
CMS2_k127_3430445_36 basal body rod protein K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 380.0
CMS2_k127_3430445_37 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 339.0
CMS2_k127_3430445_38 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 343.0
CMS2_k127_3430445_39 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 319.0
CMS2_k127_3430445_4 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.861e-296 917.0
CMS2_k127_3430445_40 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 327.0
CMS2_k127_3430445_41 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 314.0
CMS2_k127_3430445_42 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 312.0
CMS2_k127_3430445_43 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 313.0
CMS2_k127_3430445_44 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 315.0
CMS2_k127_3430445_45 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 304.0
CMS2_k127_3430445_46 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 307.0
CMS2_k127_3430445_47 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 298.0
CMS2_k127_3430445_48 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 296.0
CMS2_k127_3430445_49 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 288.0
CMS2_k127_3430445_5 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 3.989e-286 891.0
CMS2_k127_3430445_50 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004917 280.0
CMS2_k127_3430445_51 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000649 277.0
CMS2_k127_3430445_52 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002345 272.0
CMS2_k127_3430445_53 TIGRFAM flagellar basal-body rod protein FlgF K02391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001133 272.0
CMS2_k127_3430445_54 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002603 261.0
CMS2_k127_3430445_55 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002256 272.0
CMS2_k127_3430445_56 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000005724 243.0
CMS2_k127_3430445_57 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000008193 246.0
CMS2_k127_3430445_58 Type II secretory pathway component ExeA K02450,K12283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009691 248.0
CMS2_k127_3430445_59 -O-antigen K02847 - - 0.00000000000000000000000000000000000000000000000000000000000000000001641 248.0
CMS2_k127_3430445_6 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.445e-285 900.0
CMS2_k127_3430445_60 coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000002943 249.0
CMS2_k127_3430445_61 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000003581 232.0
CMS2_k127_3430445_62 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000005038 230.0
CMS2_k127_3430445_63 glycosyl transferase group 1 K12995 - 2.4.1.348 0.00000000000000000000000000000000000000000000000000000000000000001042 241.0
CMS2_k127_3430445_64 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000003812 225.0
CMS2_k127_3430445_65 Sugar ABC transporter substrate-binding protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000001892 226.0
CMS2_k127_3430445_66 epimerase dehydratase K02473,K08679 - 5.1.3.6,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000002716 222.0
CMS2_k127_3430445_67 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000000000000005353 223.0
CMS2_k127_3430445_68 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000000000000001701 198.0
CMS2_k127_3430445_69 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000002643 192.0
CMS2_k127_3430445_7 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.585e-282 872.0
CMS2_k127_3430445_70 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000304 184.0
CMS2_k127_3430445_71 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000006497 185.0
CMS2_k127_3430445_72 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000001026 181.0
CMS2_k127_3430445_73 MucB/RseB C-terminal domain K03598 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 - 0.00000000000000000000000000000000000000000000004177 181.0
CMS2_k127_3430445_74 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000005077 180.0
CMS2_k127_3430445_75 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000001013 163.0
CMS2_k127_3430445_76 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000001658 171.0
CMS2_k127_3430445_77 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000006782 155.0
CMS2_k127_3430445_78 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000001954 157.0
CMS2_k127_3430445_79 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000004468 162.0
CMS2_k127_3430445_8 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 1.036e-276 871.0
CMS2_k127_3430445_80 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000371 164.0
CMS2_k127_3430445_81 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000003098 161.0
CMS2_k127_3430445_82 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000002391 139.0
CMS2_k127_3430445_83 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000000000000000000000000000000006092 142.0
CMS2_k127_3430445_84 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000001216 134.0
CMS2_k127_3430445_85 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000001196 130.0
CMS2_k127_3430445_86 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000003706 130.0
CMS2_k127_3430445_87 Protein of unknown function (DUF2818) - - - 0.00000000000000000000000000165 115.0
CMS2_k127_3430445_88 diol metabolic process K01724 - 4.2.1.96 0.000000000000000000000000003245 114.0
CMS2_k127_3430445_89 Phosphopantetheine attachment site - - - 0.0000000000000000000000000839 109.0
CMS2_k127_3430445_9 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 8.007e-260 815.0
CMS2_k127_3430445_90 polysaccharide deacetylase - - - 0.00000000000000000000000008682 116.0
CMS2_k127_3430445_91 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000003804 105.0
CMS2_k127_3430445_92 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000006042 118.0
CMS2_k127_3430445_93 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000000000000000000000001652 109.0
CMS2_k127_3430445_94 CRS1_YhbY K07574 - - 0.000000000000000000000006737 104.0
CMS2_k127_3430445_95 glycogen (starch) synthase activity K00703,K01176,K16697,K20430 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21,3.2.1.1 0.000000000000000000001166 108.0
CMS2_k127_3430445_96 preprotein translocase K03075 - - 0.00000000000000000001529 96.0
CMS2_k127_3430445_97 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000002898 90.0
CMS2_k127_3430445_98 Cytochrome c - - - 0.00000000000004677 75.0
CMS2_k127_3430445_99 Hexapeptide repeat of succinyl-transferase - - - 0.000000000002234 74.0
CMS2_k127_3553776_0 Thermolysin metallopeptidase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009994 468.0
CMS2_k127_3553776_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000002624 186.0
CMS2_k127_3553776_2 Protein of unknown function (DUF3297) - - - 0.0000000000000000000000000000000000000000000001454 168.0
CMS2_k127_3553776_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000002289 156.0
CMS2_k127_3553776_4 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000001625 142.0
CMS2_k127_3553776_5 integral membrane protein - - - 0.0000000000000000000000000000000001634 143.0
CMS2_k127_3553776_7 Protein of unknown function (DUF3144) - - - 0.000000000005175 69.0
CMS2_k127_3553776_8 Atp-dependent helicase K03579 - 3.6.4.13 0.000000006312 57.0
CMS2_k127_3562586_0 PFAM HTH transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001652 264.0
CMS2_k127_3562586_1 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000001868 212.0
CMS2_k127_3583243_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 306.0
CMS2_k127_3583243_1 Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase K07740 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.000000000000000000000000553 110.0
CMS2_k127_360779_0 cytochrome c oxidase, subunit III K02276 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000000000001915 171.0
CMS2_k127_360779_1 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000002054 164.0
CMS2_k127_360779_2 Cytochrome C oxidase subunit II, transmembrane domain K02275 - 1.9.3.1 0.0000000000000003893 84.0
CMS2_k127_360779_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0005948 42.0
CMS2_k127_3662177_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1028.0
CMS2_k127_3662177_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.102e-261 837.0
CMS2_k127_3662177_10 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 490.0
CMS2_k127_3662177_11 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 486.0
CMS2_k127_3662177_12 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 446.0
CMS2_k127_3662177_13 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 440.0
CMS2_k127_3662177_14 Transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 368.0
CMS2_k127_3662177_15 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 362.0
CMS2_k127_3662177_16 MATE efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 374.0
CMS2_k127_3662177_17 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 373.0
CMS2_k127_3662177_18 Glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 356.0
CMS2_k127_3662177_19 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 357.0
CMS2_k127_3662177_2 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95 C K02336 - 2.7.7.7 2.033e-256 813.0
CMS2_k127_3662177_20 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 342.0
CMS2_k127_3662177_21 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 338.0
CMS2_k127_3662177_22 chemotaxis, protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 342.0
CMS2_k127_3662177_23 Methyltransferase K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 334.0
CMS2_k127_3662177_24 (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 313.0
CMS2_k127_3662177_25 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 GO:0000041,GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005385,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008144,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0072509,GO:0072511,GO:0097159,GO:0097367,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 294.0
CMS2_k127_3662177_26 COG1108 ABC-type Mn2 Zn2 transport systems permease components K09816 GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 289.0
CMS2_k127_3662177_27 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001659 268.0
CMS2_k127_3662177_28 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000448 264.0
CMS2_k127_3662177_29 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002008 255.0
CMS2_k127_3662177_3 Aminotransferase K01845 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 5.598e-220 688.0
CMS2_k127_3662177_30 PFAM Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000001625 249.0
CMS2_k127_3662177_31 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000002974 247.0
CMS2_k127_3662177_32 Glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008817 245.0
CMS2_k127_3662177_33 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000002464 222.0
CMS2_k127_3662177_34 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000006889 207.0
CMS2_k127_3662177_35 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000004121 209.0
CMS2_k127_3662177_36 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000003688 201.0
CMS2_k127_3662177_37 Secondary thiamine-phosphate synthase enzyme - - - 0.000000000000000000000000000000000000000000000000001774 185.0
CMS2_k127_3662177_38 Periplasmic solute binding protein K09815 - - 0.000000000000000000000000000000000000000000000008003 183.0
CMS2_k127_3662177_39 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000001436 177.0
CMS2_k127_3662177_4 Diguanylate cyclase - - - 2.785e-217 701.0
CMS2_k127_3662177_40 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000006097 159.0
CMS2_k127_3662177_41 O-Antigen ligase K02847 - - 0.0000000000000000000000000000000000000000006527 173.0
CMS2_k127_3662177_42 Zinc-ribbon containing domain - - - 0.000000000000000000000000000000000000000009893 159.0
CMS2_k127_3662177_43 - - - - 0.0000000000000000000000000000000000000002563 156.0
CMS2_k127_3662177_44 CoA binding domain - - - 0.0000000000000000000000000000000000004872 143.0
CMS2_k127_3662177_45 Pentapeptide - - - 0.000000000000000000000000000000005782 131.0
CMS2_k127_3662177_46 Alkylmercury lyase K00221 - 4.99.1.2 0.000000000000000000000000000008258 126.0
CMS2_k127_3662177_47 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000003987 111.0
CMS2_k127_3662177_48 YcgL domain K09902 - - 0.0000000000000000000002882 99.0
CMS2_k127_3662177_49 Zinc-finger domain - - - 0.000000000000000001357 87.0
CMS2_k127_3662177_5 COG0306 Phosphate sulphate permeases K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 609.0
CMS2_k127_3662177_50 - - - - 0.0000000000000008701 85.0
CMS2_k127_3662177_51 Protein of unknown function (DUF2892) - - - 0.0000000000001022 73.0
CMS2_k127_3662177_52 HDOD domain - - - 0.000000000009837 78.0
CMS2_k127_3662177_6 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 604.0
CMS2_k127_3662177_7 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 576.0
CMS2_k127_3662177_8 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005914 511.0
CMS2_k127_3662177_9 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 506.0
CMS2_k127_3715896_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 514.0
CMS2_k127_3715896_1 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 297.0
CMS2_k127_3715896_2 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000002828 184.0
CMS2_k127_3740969_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 425.0
CMS2_k127_3740969_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001101 278.0
CMS2_k127_3740969_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000001493 180.0
CMS2_k127_387233_0 Belongs to the ClpA ClpB family K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 516.0
CMS2_k127_387233_1 protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000901 265.0
CMS2_k127_387233_2 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337,K21008 GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000004291 169.0
CMS2_k127_387233_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000001079 152.0
CMS2_k127_387233_4 LPP20 lipoprotein - - - 0.0000000000000000000000000000000827 137.0
CMS2_k127_3908136_0 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000008279 256.0
CMS2_k127_3908136_1 regulatory protein, arsR - - - 0.00000000000000000000000000000000000000000000002218 171.0
CMS2_k127_3908136_2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000002609 161.0
CMS2_k127_3908136_3 PFAM Rhodanese-like - - - 0.000000000000000000000000000007627 123.0
CMS2_k127_398428_0 type VI secretion protein K11891 - - 1.5e-323 1026.0
CMS2_k127_398428_1 Heat shock 70 kDa protein K04043 - - 9.44e-322 994.0
CMS2_k127_398428_10 Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 505.0
CMS2_k127_398428_11 glutamate--cysteine ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 491.0
CMS2_k127_398428_12 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 422.0
CMS2_k127_398428_13 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin K10674 - 1.14.11.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 422.0
CMS2_k127_398428_14 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 418.0
CMS2_k127_398428_15 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 387.0
CMS2_k127_398428_16 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 385.0
CMS2_k127_398428_17 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 369.0
CMS2_k127_398428_18 Hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 382.0
CMS2_k127_398428_19 PFAM Succinylglutamate desuccinylase Aspartoacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 368.0
CMS2_k127_398428_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 GO:0003674,GO:0003824,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.76 7.207e-255 788.0
CMS2_k127_398428_20 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 355.0
CMS2_k127_398428_21 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 354.0
CMS2_k127_398428_22 Belongs to the agmatine deiminase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 355.0
CMS2_k127_398428_23 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 351.0
CMS2_k127_398428_24 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 319.0
CMS2_k127_398428_25 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 GO:0008104,GO:0008150,GO:0033036,GO:0051179 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009823 269.0
CMS2_k127_398428_26 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000005107 260.0
CMS2_k127_398428_27 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002821 255.0
CMS2_k127_398428_28 Type VI secretion system protein DotU K11892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001211 262.0
CMS2_k127_398428_29 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000002425 242.0
CMS2_k127_398428_3 Amino acid kinase family K00928 - 2.7.2.4 4.365e-251 780.0
CMS2_k127_398428_30 L-2,4-diaminobutyric acid acetyltransferase K06718 - 2.3.1.178 0.0000000000000000000000000000000000000000000000000000000000000000000001076 242.0
CMS2_k127_398428_31 protein conserved in bacteria K11890 - - 0.0000000000000000000000000000000000000000000000000000000000000009005 227.0
CMS2_k127_398428_32 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000007304 223.0
CMS2_k127_398428_33 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K11890,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000001036 212.0
CMS2_k127_398428_34 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000001634 203.0
CMS2_k127_398428_35 DNA polymerase III, delta' K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000003617 205.0
CMS2_k127_398428_36 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000007772 182.0
CMS2_k127_398428_37 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000001905 175.0
CMS2_k127_398428_38 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000002903 129.0
CMS2_k127_398428_39 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000005989 126.0
CMS2_k127_398428_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.37e-200 630.0
CMS2_k127_398428_40 protein conserved in bacteria K09912 - - 0.000000000000000000000000000003966 128.0
CMS2_k127_398428_41 Protein of unknown function (DUF465) - - - 0.0000000000000000000000002949 107.0
CMS2_k127_398428_42 COG1734 DnaK suppressor protein - - - 0.00000000000000000005605 93.0
CMS2_k127_398428_43 Protein conserved in bacteria - - - 0.0000000000000004129 89.0
CMS2_k127_398428_44 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 K11906 - - 0.0000000006684 64.0
CMS2_k127_398428_5 exonuclease recJ K07462 - - 3.624e-197 630.0
CMS2_k127_398428_6 Protein kinase domain K08282,K11916,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 586.0
CMS2_k127_398428_7 protein conserved in bacteria K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 559.0
CMS2_k127_398428_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 552.0
CMS2_k127_398428_9 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 512.0
CMS2_k127_4065181_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 4.161e-238 754.0
CMS2_k127_4065181_1 Response regulator receiver K03413 - - 0.000000000000000000000000000000000000000000000000000268 188.0
CMS2_k127_4065181_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000008029 173.0
CMS2_k127_4065181_3 STAS domain - - - 0.00000000000000001019 86.0
CMS2_k127_4065181_4 Chemotaxis signal transduction protein - - - 0.00000000000007797 73.0
CMS2_k127_4066981_0 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000002136 221.0
CMS2_k127_4066981_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000001236 207.0
CMS2_k127_4066981_2 antisigma factor binding - - - 0.000000000000000000000000000000000000002927 156.0
CMS2_k127_4066981_3 - - - - 0.00000000000000000002663 97.0
CMS2_k127_4066981_4 domain, Protein - - - 0.00003297 55.0
CMS2_k127_4068200_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.184e-201 636.0
CMS2_k127_4068200_1 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000000003753 232.0
CMS2_k127_4068200_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.0000000000000000000000000000000000000000000000000000002449 196.0
CMS2_k127_4068200_3 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.00000000000000000000000004138 111.0
CMS2_k127_4068200_4 diguanylate cyclase - - - 0.00000000000000000000000005108 111.0
CMS2_k127_4068200_5 His Kinase A (phosphoacceptor) domain K19694 - - 0.000000000000000000000002086 105.0
CMS2_k127_4085413_0 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 598.0
CMS2_k127_4085413_1 PFAM Binding-protein-dependent transport system inner membrane component K13895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006192 271.0
CMS2_k127_4085413_2 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000003119 229.0
CMS2_k127_4085413_3 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0000000000000000000000000000000000000000000000000000002592 197.0
CMS2_k127_4096273_0 Alpha-2-Macroglobulin K06894 - - 0.0 1536.0
CMS2_k127_4096273_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 1.096e-256 812.0
CMS2_k127_4096273_2 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 - - 0.00000000000000000000000000000000000000000000000000000000000000003007 232.0
CMS2_k127_4096273_4 D-alanyl-D-alanine carboxypeptidase - - - 0.00001395 55.0
CMS2_k127_4104771_0 Sulfatase K03760 - 2.7.8.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 542.0
CMS2_k127_4104771_1 Response regulator receiver K15012 - - 0.000000000000000000000000000000000000000000000000000000000000000000003622 239.0
CMS2_k127_4104771_2 PFAM ATP-binding region ATPase domain protein K15011 - 2.7.13.3 0.000000000000000000001914 96.0
CMS2_k127_4115916_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.747e-282 878.0
CMS2_k127_4115916_1 Molecular chaperone. Has ATPase activity K04079 - - 1.963e-263 824.0
CMS2_k127_4115916_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 328.0
CMS2_k127_4115916_11 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 300.0
CMS2_k127_4115916_12 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 287.0
CMS2_k127_4115916_14 cAMP phosphodiesterases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001569 249.0
CMS2_k127_4115916_15 Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000004246 223.0
CMS2_k127_4115916_16 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000001892 201.0
CMS2_k127_4115916_17 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000002149 196.0
CMS2_k127_4115916_18 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000001217 193.0
CMS2_k127_4115916_19 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000001139 193.0
CMS2_k127_4115916_2 Ammonium transporter K03320,K06580 - - 1.921e-212 664.0
CMS2_k127_4115916_20 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000003004 189.0
CMS2_k127_4115916_21 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000002501 180.0
CMS2_k127_4115916_22 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000001326 149.0
CMS2_k127_4115916_23 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000002141 133.0
CMS2_k127_4115916_24 Belongs to the HSP15 family K04762 - - 0.0000000000000000000000000000002788 126.0
CMS2_k127_4115916_25 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000000000001126 87.0
CMS2_k127_4115916_26 PFAM FecR protein - - - 0.0000001384 63.0
CMS2_k127_4115916_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.352e-200 633.0
CMS2_k127_4115916_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.747e-200 633.0
CMS2_k127_4115916_5 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 460.0
CMS2_k127_4115916_6 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 458.0
CMS2_k127_4115916_7 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 409.0
CMS2_k127_4115916_8 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 344.0
CMS2_k127_4115916_9 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 329.0
CMS2_k127_413718_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0003674,GO:0003824,GO:0004794,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016053,GO:0016597,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 1.605e-224 705.0
CMS2_k127_413718_1 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 3.222e-201 634.0
CMS2_k127_413718_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 327.0
CMS2_k127_413718_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000001204 178.0
CMS2_k127_413718_4 Belongs to the UPF0149 family K09895 - - 0.0000000000000000000000000000000000002197 147.0
CMS2_k127_413718_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000006403 96.0
CMS2_k127_413718_6 TIGRFAM TIGR02449 family protein K09892 - - 0.0000000004938 63.0
CMS2_k127_413718_7 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000005667 58.0
CMS2_k127_414119_0 Pfam:DUF258 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 567.0
CMS2_k127_414119_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 465.0
CMS2_k127_414119_2 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000205 233.0
CMS2_k127_414119_3 Glyoxalase-like domain - - - 0.0000000000002486 69.0
CMS2_k127_4155915_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 534.0
CMS2_k127_4155915_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000004433 103.0
CMS2_k127_4176814_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 0.0 1278.0
CMS2_k127_4176814_1 FlgJ-related protein K03796 - - 0.00000000000000000000000000000000000000000000000000000000009942 213.0
CMS2_k127_4176814_2 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000000000000002005 184.0
CMS2_k127_4204513_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.208e-200 632.0
CMS2_k127_4204513_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 557.0
CMS2_k127_4204513_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 435.0
CMS2_k127_4204513_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 403.0
CMS2_k127_4204513_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000003194 123.0
CMS2_k127_4204513_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000000002801 94.0
CMS2_k127_4204513_6 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.0000000000000001001 83.0
CMS2_k127_4204513_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000003887 72.0
CMS2_k127_4238856_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001028 249.0
CMS2_k127_4238856_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000003851 217.0
CMS2_k127_428506_0 COG1032 Fe-S oxidoreductase - - - 0.0 1099.0
CMS2_k127_428506_1 Belongs to the peptidase S16 family - - - 8.191e-229 733.0
CMS2_k127_428506_10 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 377.0
CMS2_k127_428506_11 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 367.0
CMS2_k127_428506_12 electron transfer activity K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 352.0
CMS2_k127_428506_13 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 342.0
CMS2_k127_428506_14 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 362.0
CMS2_k127_428506_15 Thioredoxin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 316.0
CMS2_k127_428506_16 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 292.0
CMS2_k127_428506_17 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001871 271.0
CMS2_k127_428506_18 PFAM PfkB domain protein K00846 - 2.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008265 275.0
CMS2_k127_428506_19 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000001067 293.0
CMS2_k127_428506_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 2.753e-225 713.0
CMS2_k127_428506_20 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001079 269.0
CMS2_k127_428506_21 hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008109 261.0
CMS2_k127_428506_22 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000001016 238.0
CMS2_k127_428506_23 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000306 256.0
CMS2_k127_428506_24 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000009032 223.0
CMS2_k127_428506_25 Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs K06219 GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097697,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000001697 225.0
CMS2_k127_428506_26 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000002449 212.0
CMS2_k127_428506_27 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.000000000000000000000000000000000000000000000000000000006899 205.0
CMS2_k127_428506_28 Peptidyl-prolyl cis-trans K03775 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010467,GO:0016151,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022417,GO:0031647,GO:0035821,GO:0036211,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043963,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0046872,GO:0046914,GO:0050821,GO:0050896,GO:0050897,GO:0051082,GO:0051604,GO:0051701,GO:0051704,GO:0051817,GO:0052027,GO:0052250,GO:0065007,GO:0065008,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000000000000000000000002553 198.0
CMS2_k127_428506_29 - - - - 0.000000000000000000000000000000000000000000000000001264 188.0
CMS2_k127_428506_3 COG0514 Superfamily II DNA helicase K03654 - 3.6.4.12 3.137e-224 715.0
CMS2_k127_428506_30 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000002518 188.0
CMS2_k127_428506_31 HIT domain - - - 0.0000000000000000000000000000000000000000000003868 171.0
CMS2_k127_428506_32 protein conserved in bacteria K09948 - - 0.0000000000000000000000000000000000000000009087 158.0
CMS2_k127_428506_33 - - - - 0.000000000000000000000000000000006721 137.0
CMS2_k127_428506_34 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000000007288 127.0
CMS2_k127_428506_35 DsrE/DsrF-like family - - - 0.00000000000000000000000000000007968 130.0
CMS2_k127_428506_36 MerR, DNA binding K08365 - - 0.000000000000000000000000000006175 123.0
CMS2_k127_428506_37 - - - - 0.0000000000000000000000000006725 114.0
CMS2_k127_428506_38 COG1716 FOG FHA domain - - - 0.000000000000000000000000003245 114.0
CMS2_k127_428506_39 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000003535 113.0
CMS2_k127_428506_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 597.0
CMS2_k127_428506_40 Protein of unknown function (DUF2288) - - - 0.000000000000000000000001608 107.0
CMS2_k127_428506_41 YtkA-like - - - 0.0000000000000000000001966 103.0
CMS2_k127_428506_42 relative of glutathione S-transferase, MAPEG superfamily K07136 - - 0.00000000000000000002657 95.0
CMS2_k127_428506_44 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000002976 81.0
CMS2_k127_428506_45 DsrE/DsrF-like family K09004 - - 0.00000000002106 71.0
CMS2_k127_428506_46 ankyrin repeat and death K14686,K15503 - - 0.00000000004156 71.0
CMS2_k127_428506_48 Histidine Phosphotransfer domain - - - 0.0000000009855 60.0
CMS2_k127_428506_5 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 597.0
CMS2_k127_428506_6 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 531.0
CMS2_k127_428506_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 428.0
CMS2_k127_428506_8 Sigma factor PP2C-like phosphatases K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 425.0
CMS2_k127_428506_9 Diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 412.0
CMS2_k127_4292517_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1437.0
CMS2_k127_4292517_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.67e-321 992.0
CMS2_k127_4292517_10 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 520.0
CMS2_k127_4292517_11 COG2202 FOG PAS PAC domain K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 517.0
CMS2_k127_4292517_12 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 509.0
CMS2_k127_4292517_13 COG2202 FOG PAS PAC domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 515.0
CMS2_k127_4292517_14 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 479.0
CMS2_k127_4292517_15 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 462.0
CMS2_k127_4292517_16 Histidine kinase K20972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 475.0
CMS2_k127_4292517_17 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 441.0
CMS2_k127_4292517_18 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 366.0
CMS2_k127_4292517_19 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 372.0
CMS2_k127_4292517_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 3.878e-287 901.0
CMS2_k127_4292517_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 354.0
CMS2_k127_4292517_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 342.0
CMS2_k127_4292517_22 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 329.0
CMS2_k127_4292517_23 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 323.0
CMS2_k127_4292517_24 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 316.0
CMS2_k127_4292517_25 Belongs to the SUA5 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 306.0
CMS2_k127_4292517_26 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 305.0
CMS2_k127_4292517_27 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 304.0
CMS2_k127_4292517_28 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 286.0
CMS2_k127_4292517_29 signal transduction histidine kinase K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 295.0
CMS2_k127_4292517_3 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 2.395e-222 693.0
CMS2_k127_4292517_30 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000001332 262.0
CMS2_k127_4292517_31 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002258 263.0
CMS2_k127_4292517_32 COG4240 Predicted kinase K15918 - 2.7.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000001211 262.0
CMS2_k127_4292517_33 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000005883 252.0
CMS2_k127_4292517_34 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002892 238.0
CMS2_k127_4292517_35 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000007033 235.0
CMS2_k127_4292517_36 plasmid maintenance K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000003342 229.0
CMS2_k127_4292517_37 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000002685 221.0
CMS2_k127_4292517_38 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000313 206.0
CMS2_k127_4292517_39 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000004279 216.0
CMS2_k127_4292517_4 TonB dependent receptor - - - 9.237e-216 690.0
CMS2_k127_4292517_40 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000003102 214.0
CMS2_k127_4292517_41 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000138 198.0
CMS2_k127_4292517_42 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000001536 201.0
CMS2_k127_4292517_43 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000007003 194.0
CMS2_k127_4292517_44 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000001193 199.0
CMS2_k127_4292517_45 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000002014 193.0
CMS2_k127_4292517_46 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000006112 213.0
CMS2_k127_4292517_47 - - - - 0.000000000000000000000000000000000000000000000000001694 185.0
CMS2_k127_4292517_48 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000101 182.0
CMS2_k127_4292517_49 Sterol carrier protein - - - 0.000000000000000000000000000000000000000000000005951 175.0
CMS2_k127_4292517_5 chemotaxis protein K03407 - 2.7.13.3 4.737e-209 669.0
CMS2_k127_4292517_50 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000002148 172.0
CMS2_k127_4292517_51 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000006862 171.0
CMS2_k127_4292517_52 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000001351 166.0
CMS2_k127_4292517_53 YCII-related domain K05527,K09780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000002164 165.0
CMS2_k127_4292517_54 MazG-like family - - - 0.0000000000000000000000000000000000000000007372 160.0
CMS2_k127_4292517_55 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000959 150.0
CMS2_k127_4292517_56 - - - - 0.00000000000000000000000000000000000001836 153.0
CMS2_k127_4292517_57 SprA-related family - - - 0.000000000000000000000000000000008297 135.0
CMS2_k127_4292517_58 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K20978 - - 0.000000000000000000000000001502 114.0
CMS2_k127_4292517_59 - - - - 0.0000000000000000000000001123 113.0
CMS2_k127_4292517_6 abc-type branched-chain amino acid transport K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 574.0
CMS2_k127_4292517_60 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000002164 97.0
CMS2_k127_4292517_61 thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000002493 87.0
CMS2_k127_4292517_62 Flagellar hook-length control K02414 - - 0.0000000000000009038 89.0
CMS2_k127_4292517_64 Response regulator receiver K15012 - - 0.0000000000002612 71.0
CMS2_k127_4292517_65 Flagellar biosynthesis chaperone K02413 - - 0.000000000003529 72.0
CMS2_k127_4292517_66 Dynamin family - - - 0.0000000003446 69.0
CMS2_k127_4292517_67 - - - - 0.000000004176 60.0
CMS2_k127_4292517_68 Recombinase zinc beta ribbon domain - - - 0.00000001368 58.0
CMS2_k127_4292517_69 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000002013 63.0
CMS2_k127_4292517_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 553.0
CMS2_k127_4292517_71 Histidine Phosphotransfer domain K20976 - - 0.0000005596 56.0
CMS2_k127_4292517_72 - - - - 0.000000653 53.0
CMS2_k127_4292517_73 - - - - 0.000000835 50.0
CMS2_k127_4292517_75 Sulphur globule protein - - - 0.00005792 53.0
CMS2_k127_4292517_77 domain, Protein - - - 0.0005898 51.0
CMS2_k127_4292517_8 (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 576.0
CMS2_k127_4292517_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 539.0
CMS2_k127_43535_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000476 279.0
CMS2_k127_43535_1 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000000000000000000000000000000171 241.0
CMS2_k127_43535_2 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000001121 115.0
CMS2_k127_43535_3 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.000000000000000000008822 97.0
CMS2_k127_43535_4 Acyl-transferase K00655 - 2.3.1.51 0.000004044 51.0
CMS2_k127_4369247_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 559.0
CMS2_k127_4369247_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 485.0
CMS2_k127_4369247_10 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000006359 150.0
CMS2_k127_4369247_11 Pas domain - - - 0.00000000000000000000000000000004935 145.0
CMS2_k127_4369247_12 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000002434 118.0
CMS2_k127_4369247_13 Response regulators consisting of a CheY-like receiver domain and a K07662 - - 0.000000000008373 74.0
CMS2_k127_4369247_14 - - - - 0.0007529 46.0
CMS2_k127_4369247_2 Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 328.0
CMS2_k127_4369247_3 Diguanylate cyclase phosphodiesterase with PAS PAC and GAF sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004994 269.0
CMS2_k127_4369247_4 2OG-Fe(II) oxygenase K07394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006696 252.0
CMS2_k127_4369247_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000002319 241.0
CMS2_k127_4369247_6 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000006227 248.0
CMS2_k127_4369247_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000001645 235.0
CMS2_k127_4369247_8 Protein of unknown function (DUF418) K07148 - - 0.000000000000000000000000000000000000000000000000000000000002925 225.0
CMS2_k127_4369247_9 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000001684 170.0
CMS2_k127_439134_0 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003234 261.0
CMS2_k127_439134_1 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000002771 154.0
CMS2_k127_439134_2 Cytochrome c K17223 - - 0.000000000000000000000000000000005563 131.0
CMS2_k127_4395903_0 Fumarate reductase flavoprotein C-term K00394 - 1.8.99.2 0.0 1257.0
CMS2_k127_4395903_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.115e-311 967.0
CMS2_k127_4395903_10 Galactose-1-phosphate uridyl transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 568.0
CMS2_k127_4395903_11 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 557.0
CMS2_k127_4395903_12 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 476.0
CMS2_k127_4395903_13 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 439.0
CMS2_k127_4395903_14 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 405.0
CMS2_k127_4395903_15 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 378.0
CMS2_k127_4395903_16 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 376.0
CMS2_k127_4395903_17 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 350.0
CMS2_k127_4395903_18 TIGRFAM cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 344.0
CMS2_k127_4395903_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 338.0
CMS2_k127_4395903_2 redox protein, regulator of disulfide bond formation K09136 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047429,GO:0047693,GO:0071704,GO:1901564 - 3.14e-271 844.0
CMS2_k127_4395903_20 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 319.0
CMS2_k127_4395903_21 PFAM Fructosamine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 322.0
CMS2_k127_4395903_22 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 308.0
CMS2_k127_4395903_23 PhnA domain K06193 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 295.0
CMS2_k127_4395903_24 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003882 266.0
CMS2_k127_4395903_25 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001782 263.0
CMS2_k127_4395903_26 PFAM Protein kinase domain K00384,K03407,K11527 - 1.8.1.9,2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000271 279.0
CMS2_k127_4395903_27 Histidine triad (Hit) protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003526 248.0
CMS2_k127_4395903_28 PFAM DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001125 249.0
CMS2_k127_4395903_29 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001407 258.0
CMS2_k127_4395903_3 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 3.087e-262 813.0
CMS2_k127_4395903_30 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001671 231.0
CMS2_k127_4395903_31 Domain of unknown function (DUF4279) - - - 0.000000000000000000000000000000000000000000000000000000000001521 211.0
CMS2_k127_4395903_32 Protein of unknown function (DUF1415) K09941 - - 0.0000000000000000000000000000000000000000000000000000000001313 208.0
CMS2_k127_4395903_33 - - - - 0.0000000000000000000000000000000000000000000000000000004023 194.0
CMS2_k127_4395903_34 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000000003944 195.0
CMS2_k127_4395903_35 - - - - 0.000000000000000000000000000000000000000000000005744 185.0
CMS2_k127_4395903_36 YCII-related domain - - - 0.000000000000000000000000000000000000000000004629 165.0
CMS2_k127_4395903_37 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000005209 164.0
CMS2_k127_4395903_38 NADP transhydrogenase K00324 - 1.6.1.2 0.000000000000000000000000000000000000000005602 155.0
CMS2_k127_4395903_39 - - - - 0.00000000000000000000000000000000000003793 156.0
CMS2_k127_4395903_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 9.358e-238 739.0
CMS2_k127_4395903_40 - - - - 0.0000000000000000000000000000000364 129.0
CMS2_k127_4395903_41 protein conserved in bacteria K09926 - - 0.000000000000000000000000000004374 125.0
CMS2_k127_4395903_42 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000001211 122.0
CMS2_k127_4395903_43 Peptidase S24-like - - - 0.0000000000000000000000000001853 118.0
CMS2_k127_4395903_44 Methyltransferase domain - - - 0.00000000000000000000006852 98.0
CMS2_k127_4395903_45 Cytochrome c - - - 0.000000000000000000001285 99.0
CMS2_k127_4395903_46 - - - - 0.000000000000000000001663 96.0
CMS2_k127_4395903_47 Bacterial-like globin K06886 - - 0.00000000000000000207 90.0
CMS2_k127_4395903_5 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 1.269e-222 693.0
CMS2_k127_4395903_50 Cbb3-type cytochrome oxidase, subunit 3 K00407 - - 0.000000008589 59.0
CMS2_k127_4395903_51 - - - - 0.0001124 47.0
CMS2_k127_4395903_52 PilZ domain - - - 0.000959 47.0
CMS2_k127_4395903_6 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 6.717e-206 647.0
CMS2_k127_4395903_7 TIGRFAM cytochrome c oxidase accessory protein FixG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 604.0
CMS2_k127_4395903_8 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 613.0
CMS2_k127_4395903_9 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 579.0
CMS2_k127_44020_0 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001302 249.0
CMS2_k127_44020_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000001272 157.0
CMS2_k127_44020_2 - - - - 0.000000000000000000000000000003726 127.0
CMS2_k127_4415125_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 377.0
CMS2_k127_4415125_1 Belongs to the UPF0276 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 335.0
CMS2_k127_4415125_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576 - - 0.0000000000000000000000000000000000000000000000000000000002556 204.0
CMS2_k127_4415125_3 - - - - 0.00000000000000000000000000000000205 131.0
CMS2_k127_4415125_4 - - - - 0.000000000000000000000002166 104.0
CMS2_k127_4415125_5 - - - - 0.000000000000000000002179 95.0
CMS2_k127_4415125_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576 - - 0.0000000000000000006303 89.0
CMS2_k127_4415125_7 NMT1-like family K15576 - - 0.0000000000008881 68.0
CMS2_k127_4446631_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 351.0
CMS2_k127_4446631_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 320.0
CMS2_k127_4446631_2 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006194 275.0
CMS2_k127_4446631_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000001171 182.0
CMS2_k127_4446631_5 - - - - 0.00000000000000000000000000000002829 128.0
CMS2_k127_4478768_0 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 418.0
CMS2_k127_4478768_1 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 326.0
CMS2_k127_4478768_2 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009412 267.0
CMS2_k127_4478768_3 ferredoxin-type protein napF K02572 - - 0.00000000000000000000000000000000000000000000001058 177.0
CMS2_k127_4478768_4 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000002141 146.0
CMS2_k127_4478768_5 oxygen carrier activity K07216 - - 0.00000000000000000000000000201 117.0
CMS2_k127_4478768_6 Invasion gene expression up-regulator - - - 0.000000000000000000000000002866 118.0
CMS2_k127_4478768_7 - - - - 0.00000000000002036 74.0
CMS2_k127_4482641_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 396.0
CMS2_k127_4482641_1 COG0223 Methionyl-tRNA formyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 344.0
CMS2_k127_4482641_2 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 327.0
CMS2_k127_4482641_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001033 250.0
CMS2_k127_4482641_4 Molybdopterin-guanine dinucleotide biosynthesis protein MobA K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000003606 181.0
CMS2_k127_4482641_5 Putative capsular polysaccharide synthesis protein - - - 0.000000000000000000000000000001019 132.0
CMS2_k127_4482641_6 PFAM Integrase catalytic - - - 0.0001562 45.0
CMS2_k127_4521396_0 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000003364 220.0
CMS2_k127_4521396_1 ACT domain K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000001074 190.0
CMS2_k127_4521396_2 SMART GGDEF domain containing protein - - - 0.00000000000000000000000000000001708 134.0
CMS2_k127_4527311_0 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 527.0
CMS2_k127_4527311_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 371.0
CMS2_k127_4527311_2 - - - - 0.0000000000000000000000000000000000000000000000004982 178.0
CMS2_k127_4527311_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000007666 115.0
CMS2_k127_4557015_0 Belongs to the ClpA ClpB family K11907 - - 2.239e-302 946.0
CMS2_k127_4557015_1 Type VI secretion system effector (Hcp1 K11903 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009052 248.0
CMS2_k127_4655985_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1420.0
CMS2_k127_4655985_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1403.0
CMS2_k127_4655985_10 chemotaxis, protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 597.0
CMS2_k127_4655985_11 Phosphoribosylformylglycinamidine cyclo-ligase K01933 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 475.0
CMS2_k127_4655985_12 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 464.0
CMS2_k127_4655985_13 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 471.0
CMS2_k127_4655985_14 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 460.0
CMS2_k127_4655985_15 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 434.0
CMS2_k127_4655985_16 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 407.0
CMS2_k127_4655985_17 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009834 404.0
CMS2_k127_4655985_18 His Kinase A (phosphoacceptor) domain K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 412.0
CMS2_k127_4655985_19 AI-2E family transporter K03548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 387.0
CMS2_k127_4655985_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1245.0
CMS2_k127_4655985_20 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 395.0
CMS2_k127_4655985_21 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 369.0
CMS2_k127_4655985_22 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 366.0
CMS2_k127_4655985_23 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 366.0
CMS2_k127_4655985_24 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 366.0
CMS2_k127_4655985_25 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 365.0
CMS2_k127_4655985_26 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 344.0
CMS2_k127_4655985_27 TIGRFAM TIGR02099 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 369.0
CMS2_k127_4655985_28 PFAM CBS domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009177 327.0
CMS2_k127_4655985_29 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 314.0
CMS2_k127_4655985_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 1.081e-249 782.0
CMS2_k127_4655985_30 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 308.0
CMS2_k127_4655985_31 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 297.0
CMS2_k127_4655985_32 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004385 273.0
CMS2_k127_4655985_33 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 261.0
CMS2_k127_4655985_34 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007332 256.0
CMS2_k127_4655985_35 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000169 256.0
CMS2_k127_4655985_36 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002411 248.0
CMS2_k127_4655985_37 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004624 249.0
CMS2_k127_4655985_38 Peroxiredoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000007836 240.0
CMS2_k127_4655985_39 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000009813 240.0
CMS2_k127_4655985_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.475e-249 781.0
CMS2_k127_4655985_40 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000001121 233.0
CMS2_k127_4655985_41 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000009075 228.0
CMS2_k127_4655985_42 Belongs to the DnaA family. HdA subfamily K10763 - - 0.0000000000000000000000000000000000000000000000000000000000009459 217.0
CMS2_k127_4655985_43 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000000000000000000000000000198 215.0
CMS2_k127_4655985_44 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000005898 220.0
CMS2_k127_4655985_45 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000001084 211.0
CMS2_k127_4655985_46 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000001521 207.0
CMS2_k127_4655985_47 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000001665 204.0
CMS2_k127_4655985_48 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000003307 201.0
CMS2_k127_4655985_49 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000001266 201.0
CMS2_k127_4655985_5 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 8.944e-233 734.0
CMS2_k127_4655985_50 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000002699 194.0
CMS2_k127_4655985_51 Involved in the binding of tRNA to the ribosomes K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000005586 190.0
CMS2_k127_4655985_52 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000005066 188.0
CMS2_k127_4655985_53 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000005986 189.0
CMS2_k127_4655985_54 protein conserved in bacteria K09938 - - 0.0000000000000000000000000000000000000000000000006861 189.0
CMS2_k127_4655985_55 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000008505 181.0
CMS2_k127_4655985_56 COG0424 Nucleotide-binding protein implicated in inhibition of septum formation K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.000000000000000000000000000000000000000000000002755 179.0
CMS2_k127_4655985_57 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000004503 179.0
CMS2_k127_4655985_58 g t u mismatch-specific dna glycosylase K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000154 176.0
CMS2_k127_4655985_59 - K09004 - - 0.00000000000000000000000000000000000000000000001683 174.0
CMS2_k127_4655985_6 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.422e-217 681.0
CMS2_k127_4655985_60 PFAM Amino acid-binding ACT K03567 - - 0.00000000000000000000000000000000000000000000004054 175.0
CMS2_k127_4655985_61 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000006198 171.0
CMS2_k127_4655985_62 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000006296 170.0
CMS2_k127_4655985_63 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000001745 171.0
CMS2_k127_4655985_64 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000000004251 168.0
CMS2_k127_4655985_65 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000002221 165.0
CMS2_k127_4655985_66 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000002503 167.0
CMS2_k127_4655985_67 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000003489 166.0
CMS2_k127_4655985_68 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000000000002486 159.0
CMS2_k127_4655985_69 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000000004886 161.0
CMS2_k127_4655985_7 TIGRFAM ribonuclease, Rne Rng family K08301 - - 5.8e-209 659.0
CMS2_k127_4655985_70 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000001808 158.0
CMS2_k127_4655985_71 - K09004 - - 0.0000000000000000000000000000000000000007883 152.0
CMS2_k127_4655985_72 PFAM MerC mercury resistance protein K19058 - - 0.0000000000000000000000000000000000002893 145.0
CMS2_k127_4655985_73 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000005072 133.0
CMS2_k127_4655985_74 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000001412 131.0
CMS2_k127_4655985_75 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000163 135.0
CMS2_k127_4655985_76 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000004074 129.0
CMS2_k127_4655985_77 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000003561 126.0
CMS2_k127_4655985_78 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000000000000000247 129.0
CMS2_k127_4655985_79 LysM domain - - - 0.0000000000000000000000000001118 124.0
CMS2_k127_4655985_8 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 2.96e-204 645.0
CMS2_k127_4655985_80 AntiSigma factor - - - 0.0000000000000000000000000002755 124.0
CMS2_k127_4655985_81 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000007075 114.0
CMS2_k127_4655985_82 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000000000000003564 109.0
CMS2_k127_4655985_83 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000002877 98.0
CMS2_k127_4655985_84 - - - - 0.0000000000000000000005467 99.0
CMS2_k127_4655985_85 Ribosomal protein L30 K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000008999 92.0
CMS2_k127_4655985_86 Predicted membrane protein (DUF2069) - - - 0.00000000000000000004371 95.0
CMS2_k127_4655985_87 Zinc-ribbon containing domain - - - 0.000000000000000001775 92.0
CMS2_k127_4655985_88 Late competence development protein ComFB - - - 0.00000000000000004614 84.0
CMS2_k127_4655985_89 Ribosomal protein L36 K02919 - - 0.00000000000001502 73.0
CMS2_k127_4655985_9 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 603.0
CMS2_k127_4655985_90 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000003419 74.0
CMS2_k127_4655985_91 Protein of unknown function (DUF3108) - - - 0.00000000000223 76.0
CMS2_k127_4655985_93 Biotin-requiring enzyme K03585 - - 0.0000002098 61.0
CMS2_k127_4655985_94 Domain of unknown function (DUF4124) - - - 0.000004811 54.0
CMS2_k127_4655985_95 - - - - 0.0004605 52.0
CMS2_k127_4660936_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 8.686e-281 871.0
CMS2_k127_4660936_1 STAS domain - - - 1.727e-216 687.0
CMS2_k127_4660936_10 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000004265 238.0
CMS2_k127_4660936_11 atp synthase K02115 - - 0.00000000000000000000000000000000000000000000000000000000001703 215.0
CMS2_k127_4660936_12 Protein of unknown function, DUF393 - - - 0.00000000000000000000000000000000000000003414 155.0
CMS2_k127_4660936_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 584.0
CMS2_k127_4660936_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 448.0
CMS2_k127_4660936_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 428.0
CMS2_k127_4660936_5 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 400.0
CMS2_k127_4660936_6 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 377.0
CMS2_k127_4660936_7 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 306.0
CMS2_k127_4660936_8 XRE family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001715 271.0
CMS2_k127_4660936_9 PFAM cobalamin (vitamin B12) biosynthesis CbiX - - - 0.00000000000000000000000000000000000000000000000000000000000000000001051 244.0
CMS2_k127_4745240_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000001326 189.0
CMS2_k127_4745240_1 PBP superfamily domain K02040 - - 0.000000003287 64.0
CMS2_k127_4762465_0 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000153 265.0
CMS2_k127_4762465_1 Crp Fnr family - - - 0.000000000000000000000000000000000000000004194 155.0
CMS2_k127_4762465_2 double-strand break repair K09946 GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000001148 147.0
CMS2_k127_4762465_3 - - - - 0.00000000000000000000000000000000001185 138.0
CMS2_k127_4762465_4 SMART Transport-associated and nodulation - - - 0.000000000000000000000000000000007845 131.0
CMS2_k127_4812375_0 chemotaxis, protein K03406 - - 1.333e-285 896.0
CMS2_k127_4812375_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 608.0
CMS2_k127_4812375_10 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000101 219.0
CMS2_k127_4812375_11 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000002339 198.0
CMS2_k127_4812375_12 Iron--sulfur cluster insertion protein erpA K15724 - - 0.00000000000000000000000000000000000000000000000006782 180.0
CMS2_k127_4812375_13 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000002985 171.0
CMS2_k127_4812375_14 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000002168 156.0
CMS2_k127_4812375_15 Glutathione peroxidase - - - 0.000000000000000000000000000000000001189 143.0
CMS2_k127_4812375_16 - - - - 0.0000000000000000005031 96.0
CMS2_k127_4812375_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 557.0
CMS2_k127_4812375_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 476.0
CMS2_k127_4812375_4 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 392.0
CMS2_k127_4812375_5 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 388.0
CMS2_k127_4812375_6 Di-haem cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 367.0
CMS2_k127_4812375_7 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001665 280.0
CMS2_k127_4812375_8 Phosphoserine phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000198 278.0
CMS2_k127_4812375_9 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000001963 225.0
CMS2_k127_4926922_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 1.025e-272 849.0
CMS2_k127_4926922_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.068e-211 669.0
CMS2_k127_4926922_10 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 391.0
CMS2_k127_4926922_11 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 349.0
CMS2_k127_4926922_12 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 342.0
CMS2_k127_4926922_13 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 340.0
CMS2_k127_4926922_14 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 327.0
CMS2_k127_4926922_15 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 318.0
CMS2_k127_4926922_16 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 314.0
CMS2_k127_4926922_17 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 319.0
CMS2_k127_4926922_18 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 287.0
CMS2_k127_4926922_19 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003862 261.0
CMS2_k127_4926922_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 5.558e-194 614.0
CMS2_k127_4926922_20 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000002978 257.0
CMS2_k127_4926922_21 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003383 265.0
CMS2_k127_4926922_22 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000001319 233.0
CMS2_k127_4926922_23 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000001738 223.0
CMS2_k127_4926922_24 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000008026 202.0
CMS2_k127_4926922_25 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000005303 206.0
CMS2_k127_4926922_26 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000000003825 185.0
CMS2_k127_4926922_27 PFAM ApaG domain protein K06195 - - 0.0000000000000000000000000000000000000000000000000334 182.0
CMS2_k127_4926922_28 TraB family K09973 - - 0.00000000000000000000000000000000000005309 155.0
CMS2_k127_4926922_29 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000001119 138.0
CMS2_k127_4926922_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009994 537.0
CMS2_k127_4926922_30 - - - - 0.00000001472 55.0
CMS2_k127_4926922_31 - - - - 0.00001274 55.0
CMS2_k127_4926922_4 COG4992 Ornithine acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 511.0
CMS2_k127_4926922_5 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 492.0
CMS2_k127_4926922_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 472.0
CMS2_k127_4926922_7 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 467.0
CMS2_k127_4926922_8 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 462.0
CMS2_k127_4926922_9 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 398.0
CMS2_k127_4943177_0 Parallel beta-helix repeats - - - 0.0 1041.0
CMS2_k127_4943177_1 response regulator K14979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000389 249.0
CMS2_k127_5079341_0 response regulator receiver K02487,K06596 - - 0.0 1288.0
CMS2_k127_5079341_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.484e-256 796.0
CMS2_k127_5079341_10 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 386.0
CMS2_k127_5079341_11 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 337.0
CMS2_k127_5079341_12 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009632 261.0
CMS2_k127_5079341_13 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000001558 229.0
CMS2_k127_5079341_14 response regulator receiver K02657 - - 0.00000000000000000000000000000000000000000000000000000000000000001935 226.0
CMS2_k127_5079341_15 phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000006243 218.0
CMS2_k127_5079341_16 RNA methyltransferase K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000007594 218.0
CMS2_k127_5079341_17 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000008972 214.0
CMS2_k127_5079341_18 response regulator receiver K02658 - - 0.000000000000000000000000000000000000000000000002069 175.0
CMS2_k127_5079341_19 chemotaxis signal transduction protein K02659 - - 0.000000000000000000000000000000000000000000003057 169.0
CMS2_k127_5079341_2 chemotaxis K02660 - - 2.068e-224 714.0
CMS2_k127_5079341_20 PhnA Zinc-Ribbon K06193 - - 0.000000000000000000000000000000000000000003218 157.0
CMS2_k127_5079341_21 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000007852 155.0
CMS2_k127_5079341_22 Methyltransferase domain - - - 0.0000000000000000000000004023 113.0
CMS2_k127_5079341_23 Two component signalling adaptor domain K06598 - - 0.0000000000000000002524 93.0
CMS2_k127_5079341_25 Domain of unknown function (DUF4136) - - - 0.0002699 44.0
CMS2_k127_5079341_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 1.653e-215 676.0
CMS2_k127_5079341_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.733e-202 634.0
CMS2_k127_5079341_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 572.0
CMS2_k127_5079341_6 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 469.0
CMS2_k127_5079341_7 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 473.0
CMS2_k127_5079341_8 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 417.0
CMS2_k127_5079341_9 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 381.0
CMS2_k127_5116760_0 Diguanylate cyclase - - - 2.141e-225 714.0
CMS2_k127_5116760_1 PFAM EAL domain K21025 - - 0.0000000000000000000000000000000000000000000000000000000002334 208.0
CMS2_k127_5116760_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.00002419 46.0
CMS2_k127_5118987_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 556.0
CMS2_k127_5118987_1 L-2,4-diaminobutyric acid acetyltransferase K06718 - 2.3.1.178 0.00000000000000000000000000000000000000000000000000000000000000009562 225.0
CMS2_k127_5118987_2 LysR substrate binding domain K04761 - - 0.00000000000000000000000000000000000000000000000000000000001226 210.0
CMS2_k127_5123350_0 glutamate--cysteine ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 473.0
CMS2_k127_5123350_1 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008641 271.0
CMS2_k127_5123350_2 Putative zinc- or iron-chelating domain - - - 0.0000001742 59.0
CMS2_k127_5128590_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1081.0
CMS2_k127_5128590_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 331.0
CMS2_k127_5128590_2 Protein of unknown function (DUF3570) - - - 0.0000000000000000000001035 103.0
CMS2_k127_5132290_0 Radical SAM superfamily K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 597.0
CMS2_k127_5132290_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 451.0
CMS2_k127_5132290_2 - - - - 0.000000000000000000000000000000000003666 143.0
CMS2_k127_5132290_3 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000001682 136.0
CMS2_k127_5135048_0 argininosuccinate lyase K01755 - 4.3.2.1 4.43e-220 690.0
CMS2_k127_5135048_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 5.307e-209 651.0
CMS2_k127_5135048_10 COG2198 FOG HPt domain K20976 - - 0.00000001029 61.0
CMS2_k127_5135048_11 Phospholipase/Carboxylesterase K06999 - - 0.000003476 48.0
CMS2_k127_5135048_2 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 439.0
CMS2_k127_5135048_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001268 289.0
CMS2_k127_5135048_4 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000005106 276.0
CMS2_k127_5135048_5 Response regulator of the LytR AlgR family K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003026 263.0
CMS2_k127_5135048_6 enzyme of heme biosynthesis K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000007556 258.0
CMS2_k127_5135048_7 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000003614 164.0
CMS2_k127_5135048_8 Glutaredoxin - - - 0.000000000000000000000003896 104.0
CMS2_k127_5135048_9 - - - - 0.0000000000000000000006581 100.0
CMS2_k127_5137650_0 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 387.0
CMS2_k127_5137650_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 377.0
CMS2_k127_5137650_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 327.0
CMS2_k127_5137650_3 PFAM Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 318.0
CMS2_k127_5137650_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 316.0
CMS2_k127_5137650_5 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 GO:0002097,GO:0002098,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 285.0
CMS2_k127_5137650_6 - - - - 0.0000000000000000000000000000000000000007621 152.0
CMS2_k127_5137650_7 - - - - 0.000000000000000000000000003034 121.0
CMS2_k127_5137650_8 - - - - 0.00000000000000000000000003578 117.0
CMS2_k127_5137650_9 PFAM VanZ - - - 0.0000000000000000006177 91.0
CMS2_k127_5154921_0 Putative diguanylate phosphodiesterase - - - 1.497e-220 710.0
CMS2_k127_5154921_1 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 2.761e-207 651.0
CMS2_k127_5154921_2 DNA alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 436.0
CMS2_k127_5154921_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 302.0
CMS2_k127_5154921_4 Domain of unknown function (DUF374) - - - 0.00000000000000000000000000000000000000000000000000005238 195.0
CMS2_k127_5154921_5 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000002846 152.0
CMS2_k127_5154921_6 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000002 135.0
CMS2_k127_5154921_7 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000002146 104.0
CMS2_k127_5154921_8 PFAM RNA recognition motif - - - 0.00006465 48.0
CMS2_k127_5154921_9 Catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0001086 45.0
CMS2_k127_5161950_0 DNA polymerase III, alpha subunit K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1406.0
CMS2_k127_5161950_1 AcrB/AcrD/AcrF family - - - 5.763e-309 977.0
CMS2_k127_5161950_10 PFAM Citrate transporter - - - 1.526e-196 623.0
CMS2_k127_5161950_11 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 603.0
CMS2_k127_5161950_12 long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 598.0
CMS2_k127_5161950_13 homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 591.0
CMS2_k127_5161950_14 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 584.0
CMS2_k127_5161950_15 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 578.0
CMS2_k127_5161950_16 COG0618 Exopolyphosphatase-related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 531.0
CMS2_k127_5161950_17 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 543.0
CMS2_k127_5161950_18 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 521.0
CMS2_k127_5161950_19 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 487.0
CMS2_k127_5161950_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 2.289e-307 956.0
CMS2_k127_5161950_20 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 453.0
CMS2_k127_5161950_21 TIGRFAM RNA polymerase sigma factor RpoS K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 418.0
CMS2_k127_5161950_22 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 437.0
CMS2_k127_5161950_23 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 410.0
CMS2_k127_5161950_24 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 404.0
CMS2_k127_5161950_25 transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 400.0
CMS2_k127_5161950_26 Hpt domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 416.0
CMS2_k127_5161950_27 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 391.0
CMS2_k127_5161950_28 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 388.0
CMS2_k127_5161950_29 PFAM histone deacetylase superfamily K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 384.0
CMS2_k127_5161950_3 Domain of unknown function (DUF1974) - - - 2.35e-294 924.0
CMS2_k127_5161950_30 - K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 401.0
CMS2_k127_5161950_31 chemotaxis, protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 398.0
CMS2_k127_5161950_32 chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 380.0
CMS2_k127_5161950_33 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 374.0
CMS2_k127_5161950_34 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 345.0
CMS2_k127_5161950_35 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 322.0
CMS2_k127_5161950_36 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 321.0
CMS2_k127_5161950_37 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 316.0
CMS2_k127_5161950_38 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 302.0
CMS2_k127_5161950_39 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 295.0
CMS2_k127_5161950_4 threonine synthase K01733 - 4.2.3.1 4.343e-242 756.0
CMS2_k127_5161950_40 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000155 307.0
CMS2_k127_5161950_41 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009656 272.0
CMS2_k127_5161950_42 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001302 279.0
CMS2_k127_5161950_43 Nitroreductase family K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002625 260.0
CMS2_k127_5161950_44 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07689 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000001013 251.0
CMS2_k127_5161950_45 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002436 251.0
CMS2_k127_5161950_46 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000004011 243.0
CMS2_k127_5161950_47 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000001976 228.0
CMS2_k127_5161950_48 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000001861 220.0
CMS2_k127_5161950_49 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000004366 221.0
CMS2_k127_5161950_5 involved in Fe-S cluster assembly - - - 3.495e-234 738.0
CMS2_k127_5161950_50 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000003934 205.0
CMS2_k127_5161950_51 PFAM Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000002489 200.0
CMS2_k127_5161950_52 Elongation factor P (EF-P) OB domain K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000005003 201.0
CMS2_k127_5161950_53 Cyclase dehydrase - - - 0.0000000000000000000000000000000000000000000000000000012 195.0
CMS2_k127_5161950_54 peptidase K06194 - - 0.000000000000000000000000000000000000000000000000000007887 199.0
CMS2_k127_5161950_55 - - - - 0.00000000000000000000000000000000000000000000000000002416 198.0
CMS2_k127_5161950_56 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000001704 189.0
CMS2_k127_5161950_57 Bacterial periplasmic substrate-binding proteins - - - 0.0000000000000000000000000000000000000000000000003028 185.0
CMS2_k127_5161950_58 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000734 185.0
CMS2_k127_5161950_59 organic phosphonate transport K02044 - - 0.0000000000000000000000000000000000000000000003764 178.0
CMS2_k127_5161950_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.563e-223 708.0
CMS2_k127_5161950_60 methyl-accepting chemotaxis protein K03406,K13487 - - 0.0000000000000000000000000000000000000000001146 184.0
CMS2_k127_5161950_61 Response regulator receiver K02658 - - 0.00000000000000000000000000000000000000002079 156.0
CMS2_k127_5161950_62 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000001438 161.0
CMS2_k127_5161950_63 - - - - 0.00000000000000000000000000000000000002561 147.0
CMS2_k127_5161950_64 Chemotaxis phosphatase CheX K03409 - - 0.000000000000000000000000000000000005158 141.0
CMS2_k127_5161950_65 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000006095 139.0
CMS2_k127_5161950_66 PFAM Smr - - - 0.00000000000000000000000000000003748 132.0
CMS2_k127_5161950_67 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000005161 120.0
CMS2_k127_5161950_68 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000128 120.0
CMS2_k127_5161950_69 COG3203 Outer membrane protein (porin) - - - 0.000000000000000000000000001156 124.0
CMS2_k127_5161950_7 PFAM Aminotransferase class I and II K14261 - - 1.905e-216 676.0
CMS2_k127_5161950_70 - - - - 0.000000000000000000000000002862 119.0
CMS2_k127_5161950_71 RnfH family Ubiquitin K09801 - - 0.000000000000000000000000003112 113.0
CMS2_k127_5161950_72 GAF domain - - - 0.00000000000000000000000001596 109.0
CMS2_k127_5161950_73 cytochrome p450 - - - 0.0000000000000000000000004863 121.0
CMS2_k127_5161950_74 CheW-like domain - - - 0.000000000000000000000109 104.0
CMS2_k127_5161950_75 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000001829 101.0
CMS2_k127_5161950_76 - - - - 0.000000000000000000002399 99.0
CMS2_k127_5161950_77 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000004781 94.0
CMS2_k127_5161950_79 - - - - 0.00000000000000002462 89.0
CMS2_k127_5161950_8 Signal transduction histidine kinase, phosphotransfer (Hpt) region K13490 - - 1.234e-205 680.0
CMS2_k127_5161950_80 Protein conserved in bacteria - - - 0.0000000000000003053 91.0
CMS2_k127_5161950_83 Bacterial protein of unknown function (Gcw_chp) - - - 0.000007318 57.0
CMS2_k127_5161950_84 Caspase domain - - - 0.000392 44.0
CMS2_k127_5161950_9 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 3.848e-200 643.0
CMS2_k127_5168522_0 ABC transporter transmembrane region K06148 - - 7.644e-223 705.0
CMS2_k127_5168522_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 1.317e-212 679.0
CMS2_k127_5168522_10 COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000006022 194.0
CMS2_k127_5168522_11 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000009762 180.0
CMS2_k127_5168522_12 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000004454 168.0
CMS2_k127_5168522_13 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000001486 152.0
CMS2_k127_5168522_14 - - - - 0.000000000000000000000000000000000001016 145.0
CMS2_k127_5168522_15 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000006296 138.0
CMS2_k127_5168522_16 Cold-shock' K03704 - - 0.000000000000000000000000000003286 124.0
CMS2_k127_5168522_17 COG1278 Cold shock proteins K03704 - - 0.00000000000000000000000001596 109.0
CMS2_k127_5168522_18 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000003267 96.0
CMS2_k127_5168522_19 - - - - 0.00000000000000915 84.0
CMS2_k127_5168522_2 Diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 354.0
CMS2_k127_5168522_20 peptidyl-tyrosine sulfation - - - 0.00000000000008668 81.0
CMS2_k127_5168522_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 345.0
CMS2_k127_5168522_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 344.0
CMS2_k127_5168522_5 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 320.0
CMS2_k127_5168522_6 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 314.0
CMS2_k127_5168522_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 289.0
CMS2_k127_5168522_8 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009887 252.0
CMS2_k127_5168522_9 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000001163 213.0
CMS2_k127_5173676_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 561.0
CMS2_k127_5173676_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 308.0
CMS2_k127_5173676_2 protein conserved in bacteria - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 - 0.00000000000000000000000000000000652 136.0
CMS2_k127_5173676_3 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000004092 101.0
CMS2_k127_5176253_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 473.0
CMS2_k127_5176253_1 PFAM sigma-54 factor interaction domain-containing protein K06714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 474.0
CMS2_k127_5186440_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 0.0 1552.0
CMS2_k127_5202943_0 COG2183 Transcriptional accessory protein K06959 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 2.346e-320 997.0
CMS2_k127_5202943_1 STAS domain K03321 - - 5.274e-276 857.0
CMS2_k127_5202943_10 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 515.0
CMS2_k127_5202943_11 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 509.0
CMS2_k127_5202943_12 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 464.0
CMS2_k127_5202943_13 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 473.0
CMS2_k127_5202943_14 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 437.0
CMS2_k127_5202943_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 449.0
CMS2_k127_5202943_16 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 420.0
CMS2_k127_5202943_17 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 412.0
CMS2_k127_5202943_18 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 421.0
CMS2_k127_5202943_19 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 407.0
CMS2_k127_5202943_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.975e-242 766.0
CMS2_k127_5202943_20 Methyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 404.0
CMS2_k127_5202943_21 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 394.0
CMS2_k127_5202943_22 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 381.0
CMS2_k127_5202943_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 390.0
CMS2_k127_5202943_24 auxin efflux carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 377.0
CMS2_k127_5202943_25 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 369.0
CMS2_k127_5202943_26 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 381.0
CMS2_k127_5202943_27 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009211 389.0
CMS2_k127_5202943_28 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 342.0
CMS2_k127_5202943_29 transcriptional regulator, ArsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 323.0
CMS2_k127_5202943_3 Citrate transporter - - - 6.875e-223 698.0
CMS2_k127_5202943_30 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 322.0
CMS2_k127_5202943_31 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 304.0
CMS2_k127_5202943_32 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 296.0
CMS2_k127_5202943_33 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 295.0
CMS2_k127_5202943_34 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001815 277.0
CMS2_k127_5202943_35 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001876 265.0
CMS2_k127_5202943_36 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009175 245.0
CMS2_k127_5202943_37 Inner membrane protein PRK11099 K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000002633 250.0
CMS2_k127_5202943_38 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000001203 211.0
CMS2_k127_5202943_39 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000005126 203.0
CMS2_k127_5202943_4 Serine dehydratase beta chain K01752 - 4.3.1.17 1.126e-222 697.0
CMS2_k127_5202943_40 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000005363 201.0
CMS2_k127_5202943_41 PFAM NUDIX hydrolase K08312 - - 0.00000000000000000000000000000000000000000000000000000001782 202.0
CMS2_k127_5202943_42 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000005727 217.0
CMS2_k127_5202943_43 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000000000000002529 184.0
CMS2_k127_5202943_44 Haem-degrading - - - 0.0000000000000000000000000000000000000000000009672 174.0
CMS2_k127_5202943_45 PFAM response regulator receiver K07183 - - 0.000000000000000000000000000000000000000005219 160.0
CMS2_k127_5202943_46 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K13613 - - 0.0000000000000000000000000000000000000001871 157.0
CMS2_k127_5202943_47 COG3156 Type II secretory pathway component PulK K02460 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000003436 159.0
CMS2_k127_5202943_48 peptidylprolyl isomerase K03769 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000001039 147.0
CMS2_k127_5202943_49 - - - - 0.0000000000000000000000000000000000001908 145.0
CMS2_k127_5202943_5 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 8.482e-222 704.0
CMS2_k127_5202943_50 General secretion pathway protein J K02459 - - 0.0000000000000000000000000000000000002672 147.0
CMS2_k127_5202943_51 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000002888 147.0
CMS2_k127_5202943_52 GDSL-like Lipase/Acylhydrolase K12686 - - 0.00000000000000000000000000000000002687 147.0
CMS2_k127_5202943_53 - - - - 0.0000000000000000000000000000000001432 135.0
CMS2_k127_5202943_54 EamA-like transporter family K08978 - - 0.000000000000000000000000000001188 126.0
CMS2_k127_5202943_55 Rhomboid family - - - 0.000000000000000000000000000005626 126.0
CMS2_k127_5202943_56 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000000001597 129.0
CMS2_k127_5202943_57 COG2165 Type II secretory pathway, pseudopilin PulG K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000005995 109.0
CMS2_k127_5202943_58 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.000000000000000000000002086 105.0
CMS2_k127_5202943_59 - - - - 0.000000000000000000000002609 105.0
CMS2_k127_5202943_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 642.0
CMS2_k127_5202943_60 - - - - 0.00000000000000000003478 97.0
CMS2_k127_5202943_61 Protein of unknown function (DUF3592) - - - 0.00000000000000000004039 98.0
CMS2_k127_5202943_62 general secretion pathway protein K02457 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000002633 92.0
CMS2_k127_5202943_63 - - - - 0.00000000000000007545 85.0
CMS2_k127_5202943_64 - - - - 0.000000000000001707 79.0
CMS2_k127_5202943_65 type II secretion system protein N K02463 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000003103 79.0
CMS2_k127_5202943_66 Response regulator, receiver K01733,K22010 - 4.2.3.1 0.0000000000004482 76.0
CMS2_k127_5202943_67 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 GO:0008150,GO:0009405,GO:0044419,GO:0051704 - 0.0000000000006733 75.0
CMS2_k127_5202943_69 DsrE/DsrF-like family K09004 - - 0.000008062 55.0
CMS2_k127_5202943_7 NADH dehydrogenase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 599.0
CMS2_k127_5202943_8 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 544.0
CMS2_k127_5202943_9 Sulfate transporter K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 554.0
CMS2_k127_5227937_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.137e-250 808.0
CMS2_k127_5227937_1 NfeD-like C-terminal, partner-binding K07340 - - 0.0000000000000000000000000000000000000000000000007781 179.0
CMS2_k127_5227937_2 - - - - 0.00000000000000000000000004901 114.0
CMS2_k127_5227937_3 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000001519 77.0
CMS2_k127_52290_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 2.807e-287 897.0
CMS2_k127_52290_1 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 2.745e-249 791.0
CMS2_k127_52290_10 Synthesizes selenophosphate from selenide and ATP K01008 GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 482.0
CMS2_k127_52290_100 peptidase M42 - - - 0.00000174 51.0
CMS2_k127_52290_101 positive regulation of growth rate - - - 0.000006963 59.0
CMS2_k127_52290_102 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000644 49.0
CMS2_k127_52290_11 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 487.0
CMS2_k127_52290_12 Belongs to the UPF0176 family K07146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 470.0
CMS2_k127_52290_13 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 466.0
CMS2_k127_52290_14 S1 domain K00243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 451.0
CMS2_k127_52290_15 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 452.0
CMS2_k127_52290_16 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 454.0
CMS2_k127_52290_17 COG2202 FOG PAS PAC domain K03406,K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 459.0
CMS2_k127_52290_18 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 437.0
CMS2_k127_52290_19 P COG0025 NhaP-type Na H and K H antiporters K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 440.0
CMS2_k127_52290_2 Domain of unknown function (DUF4478) K06966 - 3.2.2.10 2.805e-228 713.0
CMS2_k127_52290_20 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 416.0
CMS2_k127_52290_21 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 392.0
CMS2_k127_52290_22 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 391.0
CMS2_k127_52290_23 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 389.0
CMS2_k127_52290_24 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 375.0
CMS2_k127_52290_25 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 361.0
CMS2_k127_52290_26 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 361.0
CMS2_k127_52290_27 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 361.0
CMS2_k127_52290_28 Phospholipase D. Active site motifs. K06131 GO:0003674,GO:0003824,GO:0004620,GO:0004630,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016298,GO:0016740,GO:0016772,GO:0016780,GO:0016787,GO:0016788,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 356.0
CMS2_k127_52290_29 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 350.0
CMS2_k127_52290_3 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 4.842e-210 664.0
CMS2_k127_52290_30 PFAM Endonuclease exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 338.0
CMS2_k127_52290_31 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 338.0
CMS2_k127_52290_32 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 319.0
CMS2_k127_52290_33 Thioredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 323.0
CMS2_k127_52290_34 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 326.0
CMS2_k127_52290_35 flagellar motor K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 314.0
CMS2_k127_52290_36 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 313.0
CMS2_k127_52290_37 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 306.0
CMS2_k127_52290_38 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 302.0
CMS2_k127_52290_39 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001713 284.0
CMS2_k127_52290_4 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 1.694e-208 669.0
CMS2_k127_52290_40 (ABC) transporter K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003294 284.0
CMS2_k127_52290_41 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003417 281.0
CMS2_k127_52290_42 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002064 266.0
CMS2_k127_52290_43 nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002458 258.0
CMS2_k127_52290_44 Role in flagellar biosynthesis K02421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002568 260.0
CMS2_k127_52290_45 Thioredoxin K07396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008619 257.0
CMS2_k127_52290_46 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002124 246.0
CMS2_k127_52290_47 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001148 239.0
CMS2_k127_52290_48 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000855 232.0
CMS2_k127_52290_49 Chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000003553 221.0
CMS2_k127_52290_5 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 2.895e-198 645.0
CMS2_k127_52290_50 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000433 225.0
CMS2_k127_52290_51 Nuclease-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000005646 231.0
CMS2_k127_52290_52 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000001769 218.0
CMS2_k127_52290_53 GDSL-like Lipase/Acylhydrolase K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000004685 216.0
CMS2_k127_52290_54 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000002097 212.0
CMS2_k127_52290_55 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000000000251 206.0
CMS2_k127_52290_56 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.000000000000000000000000000000000000000000000000000000004826 207.0
CMS2_k127_52290_57 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000005586 203.0
CMS2_k127_52290_58 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000001383 200.0
CMS2_k127_52290_59 protein conserved in archaea - - - 0.000000000000000000000000000000000000000000000000000001642 195.0
CMS2_k127_52290_6 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 602.0
CMS2_k127_52290_60 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000002643 192.0
CMS2_k127_52290_61 Belongs to the UPF0260 family K09160 - - 0.0000000000000000000000000000000000000000000000001479 180.0
CMS2_k127_52290_62 - - - - 0.0000000000000000000000000000000000000000000000004147 183.0
CMS2_k127_52290_63 PFAM Di-haem cytochrome c - - - 0.00000000000000000000000000000000000000000000001986 176.0
CMS2_k127_52290_64 Disulfide bond formation protein DsbB - - - 0.00000000000000000000000000000000000000000000002438 175.0
CMS2_k127_52290_65 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000000000002757 173.0
CMS2_k127_52290_66 Type III flagellar switch regulator (C-ring) FliN C-term K02417 GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000003448 173.0
CMS2_k127_52290_67 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000001029 167.0
CMS2_k127_52290_68 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000004426 161.0
CMS2_k127_52290_69 protein-disulfide reductase activity - - - 0.000000000000000000000000000000000001239 143.0
CMS2_k127_52290_7 M18 family aminopeptidase K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 569.0
CMS2_k127_52290_70 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000000002956 139.0
CMS2_k127_52290_71 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000007544 139.0
CMS2_k127_52290_72 COG0575 CDP-diglyceride synthetase - - - 0.00000000000000000000000000000003612 131.0
CMS2_k127_52290_73 - - - - 0.0000000000000000000000000000002573 132.0
CMS2_k127_52290_74 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000001546 121.0
CMS2_k127_52290_75 - - - - 0.000000000000000000000000000002458 123.0
CMS2_k127_52290_76 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000002526 126.0
CMS2_k127_52290_77 SNARE associated Golgi protein - - - 0.0000000000000000000000000001714 123.0
CMS2_k127_52290_78 Putative ATP-dependant zinc protease - - - 0.000000000000000000000000006687 116.0
CMS2_k127_52290_79 Role in flagellar biosynthesis K02420 - - 0.00000000000000000000000001705 110.0
CMS2_k127_52290_8 Periplasmic 7TM domain sensor diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 533.0
CMS2_k127_52290_80 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000003726 112.0
CMS2_k127_52290_81 - - - - 0.0000000000000000000000001216 118.0
CMS2_k127_52290_82 Protein of unknown function (DUF2789) - - - 0.00000000000000000000005944 99.0
CMS2_k127_52290_83 homolog of the cytoplasmic domain of flagellar protein FhlB K04061 - - 0.0000000000000000000002158 100.0
CMS2_k127_52290_84 - - - - 0.0000000000000000000003502 101.0
CMS2_k127_52290_85 peptidase M42 - - - 0.00000000000000000005824 89.0
CMS2_k127_52290_86 Cysteine-rich CPXCG - - - 0.000000000000000001844 87.0
CMS2_k127_52290_87 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.0000000000000001126 94.0
CMS2_k127_52290_88 Domain of unknown function (DUF3817) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000004877 81.0
CMS2_k127_52290_89 - - - - 0.0000000000000007696 82.0
CMS2_k127_52290_9 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) K05844 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 494.0
CMS2_k127_52290_90 Propeptide PepSY amd peptidase M4 - - - 0.000000000000003262 78.0
CMS2_k127_52290_91 COG3190 Flagellar biogenesis protein K02418 - - 0.0000000000006192 74.0
CMS2_k127_52290_92 Flagellar hook-length control protein FliK - - - 0.00000000002389 76.0
CMS2_k127_52290_93 PQ loop repeat K15383 - - 0.00000000009253 65.0
CMS2_k127_52290_94 Cell division protein DamX K03112 GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367 - 0.0000000001122 70.0
CMS2_k127_52290_95 - - - - 0.0000000005157 63.0
CMS2_k127_52290_96 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000005151 68.0
CMS2_k127_52290_97 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000611 65.0
CMS2_k127_52290_98 Protein of unknown function (DUF2802) - - - 0.000000212 57.0
CMS2_k127_52290_99 - - - - 0.000001122 57.0
CMS2_k127_5270640_0 COG2200 FOG EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002824 277.0
CMS2_k127_5270640_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000004376 109.0
CMS2_k127_5270640_2 Diguanylate cyclase - - - 0.0000000000000000002486 101.0
CMS2_k127_5280470_0 nucleoside-diphosphate sugar epimerases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 541.0
CMS2_k127_5280470_1 Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) K13007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 399.0
CMS2_k127_5280470_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 399.0
CMS2_k127_5280470_3 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 346.0
CMS2_k127_5280470_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001093 273.0
CMS2_k127_5280470_5 ADP-glyceromanno-heptose 6-epimerase activity K19997,K22320 - 1.1.1.412,5.1.3.26 0.00000000000000000000000000000000000000000000000004429 191.0
CMS2_k127_5280470_6 Sulfotransferase family - - - 0.00000000000000000000000000000000000004826 151.0
CMS2_k127_5280470_7 Glycosyltransferase like family 2 - - - 0.000000000000000000025 101.0
CMS2_k127_5291152_0 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 394.0
CMS2_k127_5291152_1 Polysaccharide chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 355.0
CMS2_k127_5291152_2 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001673 233.0
CMS2_k127_5291152_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000006138 203.0
CMS2_k127_5291152_4 - - - - 0.00000000002139 72.0
CMS2_k127_5336640_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 398.0
CMS2_k127_5336640_1 response regulator receiver K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001404 264.0
CMS2_k127_5336640_2 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000121 259.0
CMS2_k127_5336640_3 Iron-sulphur cluster biosynthesis - - - 0.0000000000000000000000000000339 119.0
CMS2_k127_5338568_0 response regulator K07712 - - 2.658e-196 622.0
CMS2_k127_5338568_1 signal transduction histidine kinase K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 357.0
CMS2_k127_5338568_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000002585 126.0
CMS2_k127_5338568_3 Domain of unknown function (DUF4124) - - - 0.00000000255 61.0
CMS2_k127_5378587_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1328.0
CMS2_k127_5378587_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1204.0
CMS2_k127_5378587_10 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.597e-196 618.0
CMS2_k127_5378587_11 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 593.0
CMS2_k127_5378587_12 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 552.0
CMS2_k127_5378587_13 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 524.0
CMS2_k127_5378587_14 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 514.0
CMS2_k127_5378587_15 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 503.0
CMS2_k127_5378587_16 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 490.0
CMS2_k127_5378587_17 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 487.0
CMS2_k127_5378587_18 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 490.0
CMS2_k127_5378587_19 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 456.0
CMS2_k127_5378587_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 0.0 1169.0
CMS2_k127_5378587_20 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 437.0
CMS2_k127_5378587_21 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 426.0
CMS2_k127_5378587_22 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 413.0
CMS2_k127_5378587_23 ATP-grasp fold domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 407.0
CMS2_k127_5378587_24 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 378.0
CMS2_k127_5378587_25 Bacterial periplasmic substrate-binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 410.0
CMS2_k127_5378587_26 Soluble lytic murein transglycosylase L domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 379.0
CMS2_k127_5378587_27 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 336.0
CMS2_k127_5378587_28 Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 317.0
CMS2_k127_5378587_29 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 309.0
CMS2_k127_5378587_3 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1047.0
CMS2_k127_5378587_30 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 306.0
CMS2_k127_5378587_31 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 299.0
CMS2_k127_5378587_32 signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001292 275.0
CMS2_k127_5378587_33 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005215 264.0
CMS2_k127_5378587_34 Uncharacterised protein family UPF0066 - GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000001671 248.0
CMS2_k127_5378587_35 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000003205 247.0
CMS2_k127_5378587_36 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000002957 234.0
CMS2_k127_5378587_37 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000004858 230.0
CMS2_k127_5378587_38 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000002665 217.0
CMS2_k127_5378587_39 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000000000000008489 218.0
CMS2_k127_5378587_4 PFAM alpha amylase, catalytic K05341 - 2.4.1.4 0.0 1041.0
CMS2_k127_5378587_40 ATP adenylyltransferase (5',5''-P-1,P-4-tetraphosphate phosphorylase II) - - - 0.000000000000000000000000000000000000000000000000000000000002132 221.0
CMS2_k127_5378587_41 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000001769 214.0
CMS2_k127_5378587_42 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000003736 202.0
CMS2_k127_5378587_43 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000005139 202.0
CMS2_k127_5378587_44 to the N-terminal domain of Lon protease K07157 - - 0.00000000000000000000000000000000000000000000000004809 184.0
CMS2_k127_5378587_45 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000002003 181.0
CMS2_k127_5378587_46 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000007762 174.0
CMS2_k127_5378587_47 Belongs to the thioredoxin family K05838 - - 0.00000000000000000000000000000000000000001104 156.0
CMS2_k127_5378587_48 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000426 155.0
CMS2_k127_5378587_49 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000128 146.0
CMS2_k127_5378587_5 HAD-superfamily hydrolase, subfamily IIB K00696 - 2.4.1.14 1.025e-305 952.0
CMS2_k127_5378587_50 GGDEF domain K21084 - 2.7.7.65 0.0000000000000000000000000000000000000163 163.0
CMS2_k127_5378587_51 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000000000000000000003801 151.0
CMS2_k127_5378587_52 Domain of unknown function (DUF1853) K09977 - - 0.000000000000000000000000000000000001048 150.0
CMS2_k127_5378587_53 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000145 127.0
CMS2_k127_5378587_54 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000000000000000002253 109.0
CMS2_k127_5378587_55 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000007657 102.0
CMS2_k127_5378587_56 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000001074 113.0
CMS2_k127_5378587_57 Sel1-like repeats. K07126 - - 0.0000000000000000000000125 108.0
CMS2_k127_5378587_58 Mut7-C RNAse domain K09122 - - 0.000000000000000000001496 101.0
CMS2_k127_5378587_59 Protein of unknown function DUF58 - - - 0.00000000000000000006874 101.0
CMS2_k127_5378587_6 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 8.833e-237 743.0
CMS2_k127_5378587_60 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000001448 92.0
CMS2_k127_5378587_61 Modulates RecA activity K03565 - - 0.000000000000000005816 90.0
CMS2_k127_5378587_62 Peptidoglycan-binding protein, CsiV - - - 0.0000000000000002933 89.0
CMS2_k127_5378587_63 Sel1-like repeats. K07126 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008150,GO:0009966,GO:0009967,GO:0009987,GO:0010646,GO:0010647,GO:0016043,GO:0023051,GO:0023056,GO:0031505,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0065007,GO:0071554,GO:0071555,GO:0071840,GO:0071852 - 0.000000000001321 80.0
CMS2_k127_5378587_66 protein ubiquitination K15502,K15503 - - 0.0000000002058 73.0
CMS2_k127_5378587_67 - - - - 0.00000004716 54.0
CMS2_k127_5378587_68 von Willebrand factor (vWF) type A domain K07114 - - 0.00003452 55.0
CMS2_k127_5378587_69 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0001091 49.0
CMS2_k127_5378587_7 Belongs to the glycosyl hydrolase 57 family - - - 1.66e-224 708.0
CMS2_k127_5378587_70 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues - - - 0.0001295 54.0
CMS2_k127_5378587_8 Belongs to the GPI family K01810 - 5.3.1.9 2.39e-222 701.0
CMS2_k127_5378587_9 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.201e-218 682.0
CMS2_k127_5406970_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 431.0
CMS2_k127_5406970_1 Iron permease K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007462 283.0
CMS2_k127_5406970_2 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001892 285.0
CMS2_k127_5406970_3 Uncharacterized protein conserved in bacteria (DUF2130) - - - 0.000000000000000000000000000000000000000000001498 170.0
CMS2_k127_5406970_4 Cupredoxin-like domain - - - 0.0000000000000000000000000000007303 124.0
CMS2_k127_5412355_0 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 5.312e-229 714.0
CMS2_k127_5412355_1 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 459.0
CMS2_k127_5412355_2 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K02029 - 3.6.3.21 0.0008741 42.0
CMS2_k127_5412933_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1387.0
CMS2_k127_5412933_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.963e-295 914.0
CMS2_k127_5412933_10 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 364.0
CMS2_k127_5412933_11 Histidine kinase K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 376.0
CMS2_k127_5412933_12 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 343.0
CMS2_k127_5412933_13 C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 338.0
CMS2_k127_5412933_14 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 318.0
CMS2_k127_5412933_15 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 304.0
CMS2_k127_5412933_16 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001664 272.0
CMS2_k127_5412933_17 COG0811 Biopolymer transport proteins K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0017038,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0033036,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005467 264.0
CMS2_k127_5412933_18 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009323 253.0
CMS2_k127_5412933_19 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000002382 240.0
CMS2_k127_5412933_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 602.0
CMS2_k127_5412933_20 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.0000000000000000000000000000000000000000000000000000000000000000005873 246.0
CMS2_k127_5412933_21 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000007052 231.0
CMS2_k127_5412933_22 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000007976 232.0
CMS2_k127_5412933_23 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000001322 201.0
CMS2_k127_5412933_24 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000003484 194.0
CMS2_k127_5412933_25 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000007959 196.0
CMS2_k127_5412933_26 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000001348 184.0
CMS2_k127_5412933_27 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000001359 182.0
CMS2_k127_5412933_28 - - - - 0.000000000000000000000000000000000000000000005056 174.0
CMS2_k127_5412933_29 Biopolymer K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000005894 164.0
CMS2_k127_5412933_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 589.0
CMS2_k127_5412933_30 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000000000000000000000003803 162.0
CMS2_k127_5412933_31 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000006324 160.0
CMS2_k127_5412933_32 PFAM Amino acid-binding ACT K03567 - - 0.0000000000000000000000000000000000000001574 156.0
CMS2_k127_5412933_33 ECF sigma factor K03088 - - 0.0000000000000000000000000000000003818 138.0
CMS2_k127_5412933_34 Sulfur oxidation K17223 - - 0.000000000000000000000000000000001141 133.0
CMS2_k127_5412933_35 NTP pyrophosphohydrolases including oxidative damage repair enzymes K08310 - 3.6.1.67 0.00000000000000000000000000000003199 131.0
CMS2_k127_5412933_36 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000001575 117.0
CMS2_k127_5412933_37 PFAM Rhodanese-like - - - 0.0000000000000000000000001154 109.0
CMS2_k127_5412933_38 COG0457 FOG TPR repeat - - - 0.000000000000000000000001586 117.0
CMS2_k127_5412933_39 TolA C-terminal K03646 - - 0.0000000000000000001155 99.0
CMS2_k127_5412933_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 523.0
CMS2_k127_5412933_40 B-1 B cell differentiation - - - 0.0000000000000001973 93.0
CMS2_k127_5412933_41 Prokaryotic N-terminal methylation motif K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000000000000004392 85.0
CMS2_k127_5412933_42 integral membrane protein - - - 0.000000000000003103 84.0
CMS2_k127_5412933_44 - K06950 - - 0.000001559 53.0
CMS2_k127_5412933_5 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 522.0
CMS2_k127_5412933_6 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 484.0
CMS2_k127_5412933_7 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 481.0
CMS2_k127_5412933_8 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 383.0
CMS2_k127_5412933_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 377.0
CMS2_k127_5428988_0 Peptidase, M16 K06972 - - 0.0 1184.0
CMS2_k127_5428988_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1117.0
CMS2_k127_5428988_10 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 443.0
CMS2_k127_5428988_11 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 409.0
CMS2_k127_5428988_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 404.0
CMS2_k127_5428988_13 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 420.0
CMS2_k127_5428988_14 Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 391.0
CMS2_k127_5428988_15 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 388.0
CMS2_k127_5428988_16 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009373 376.0
CMS2_k127_5428988_17 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 396.0
CMS2_k127_5428988_18 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 369.0
CMS2_k127_5428988_19 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 378.0
CMS2_k127_5428988_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.4e-322 1017.0
CMS2_k127_5428988_20 AFG1-like ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 355.0
CMS2_k127_5428988_21 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 341.0
CMS2_k127_5428988_22 ChrR Cupin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 336.0
CMS2_k127_5428988_23 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 336.0
CMS2_k127_5428988_24 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 328.0
CMS2_k127_5428988_25 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 320.0
CMS2_k127_5428988_26 alpha/beta hydrolase fold K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 325.0
CMS2_k127_5428988_27 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 315.0
CMS2_k127_5428988_28 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 297.0
CMS2_k127_5428988_29 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 294.0
CMS2_k127_5428988_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.53e-277 867.0
CMS2_k127_5428988_30 TIGRFAM squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001822 284.0
CMS2_k127_5428988_31 short-chain dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 270.0
CMS2_k127_5428988_32 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003461 262.0
CMS2_k127_5428988_33 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002408 261.0
CMS2_k127_5428988_34 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000002182 235.0
CMS2_k127_5428988_35 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0046690,GO:0050896 2.1.1.67 0.00000000000000000000000000000000000000000000000000000000000001212 222.0
CMS2_k127_5428988_36 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 - - 0.0000000000000000000000000000000000000000000000000000000005156 210.0
CMS2_k127_5428988_37 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000000000000000000000000000000000001269 201.0
CMS2_k127_5428988_38 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 0.0000000000000000000000000000000000000000000000000000002838 197.0
CMS2_k127_5428988_39 response regulator K15012 - - 0.000000000000000000000000000000000000000000000000000461 187.0
CMS2_k127_5428988_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.826e-273 847.0
CMS2_k127_5428988_40 - - - - 0.00000000000000000000000000000000000000000000000001078 190.0
CMS2_k127_5428988_41 - - - - 0.00000000000000000000000000000000000000000003093 165.0
CMS2_k127_5428988_42 protein conserved in bacteria K11022 - - 0.000000000000000000000000000000000000000001687 157.0
CMS2_k127_5428988_43 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000008256 161.0
CMS2_k127_5428988_44 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000003233 155.0
CMS2_k127_5428988_45 - - - - 0.000000000000000000000000000000001394 136.0
CMS2_k127_5428988_46 - - - - 0.0000000000000000000000000000001829 134.0
CMS2_k127_5428988_47 efflux transmembrane transporter activity - - - 0.0000000000000000003692 101.0
CMS2_k127_5428988_48 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.0000000000000003964 88.0
CMS2_k127_5428988_49 - - - - 0.000000000000007998 80.0
CMS2_k127_5428988_5 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 5.179e-266 846.0
CMS2_k127_5428988_50 Belongs to the skp family K06142 - - 0.00000000000003498 79.0
CMS2_k127_5428988_52 - - - - 0.00000000009948 65.0
CMS2_k127_5428988_53 - - - - 0.000000007086 66.0
CMS2_k127_5428988_54 - - - - 0.0000001105 55.0
CMS2_k127_5428988_55 Belongs to the SlyX family K03745 - - 0.000004554 52.0
CMS2_k127_5428988_56 Belongs to the globin family K05916 - 1.14.12.17 0.00006582 50.0
CMS2_k127_5428988_57 COG3070 Regulator of competence-specific genes K07343 GO:0006355,GO:0006810,GO:0007154,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009605,GO:0009889,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0015931,GO:0019219,GO:0019222,GO:0030420,GO:0031323,GO:0031326,GO:0031344,GO:0031346,GO:0031668,GO:0044087,GO:0044089,GO:0044093,GO:0044764,GO:0048518,GO:0048522,GO:0050657,GO:0050789,GO:0050794,GO:0050896,GO:0051027,GO:0051090,GO:0051091,GO:0051128,GO:0051130,GO:0051171,GO:0051179,GO:0051234,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0060491,GO:0065007,GO:0065009,GO:0071496,GO:0071702,GO:0071705,GO:0080090,GO:0098657,GO:1903506,GO:1903656,GO:1903658,GO:2000112,GO:2001141 - 0.0009014 46.0
CMS2_k127_5428988_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.542e-212 683.0
CMS2_k127_5428988_7 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 542.0
CMS2_k127_5428988_8 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 497.0
CMS2_k127_5428988_9 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 497.0
CMS2_k127_5526462_0 Histidine kinase K07673,K07674 GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 413.0
CMS2_k127_5526462_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004078 263.0
CMS2_k127_5526462_2 helix_turn_helix, Lux Regulon K07684 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090352,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903314,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000003484 234.0
CMS2_k127_5526462_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000001536 132.0
CMS2_k127_5562115_0 Peptidogalycan biosysnthesis/recognition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 368.0
CMS2_k127_5562115_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 293.0
CMS2_k127_5562115_2 Protein involved in cellulose biosynthesis - - - 0.00001405 48.0
CMS2_k127_5597127_0 Helicase K03722 - 3.6.4.12 9.889e-207 661.0
CMS2_k127_5597127_1 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 4.109e-204 660.0
CMS2_k127_5597127_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 565.0
CMS2_k127_5597127_3 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 460.0
CMS2_k127_5597127_4 GAF domain - - - 0.00000000000000000000000000000003137 142.0
CMS2_k127_5649833_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1440.0
CMS2_k127_5649833_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1130.0
CMS2_k127_5649833_10 Fad linked oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 535.0
CMS2_k127_5649833_11 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 485.0
CMS2_k127_5649833_12 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 457.0
CMS2_k127_5649833_13 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 408.0
CMS2_k127_5649833_14 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 399.0
CMS2_k127_5649833_15 iron assimilation K07223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 359.0
CMS2_k127_5649833_16 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 358.0
CMS2_k127_5649833_17 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 363.0
CMS2_k127_5649833_18 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 353.0
CMS2_k127_5649833_19 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 319.0
CMS2_k127_5649833_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 - 4.079e-318 982.0
CMS2_k127_5649833_20 Permease YjgP YjgQ K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 318.0
CMS2_k127_5649833_21 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 313.0
CMS2_k127_5649833_22 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 305.0
CMS2_k127_5649833_23 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007233 265.0
CMS2_k127_5649833_24 Permease YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003993 250.0
CMS2_k127_5649833_25 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000005412 237.0
CMS2_k127_5649833_26 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000003256 215.0
CMS2_k127_5649833_27 - - - - 0.00000000000000000000000000000000000000000000000000004265 193.0
CMS2_k127_5649833_28 GtrA-like protein - - - 0.00000000000000000000000000000000000000000000000001398 182.0
CMS2_k127_5649833_29 Divergent PAP2 family K09775 - - 0.000000000000000000000000000000000000000000000000347 178.0
CMS2_k127_5649833_3 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 3.133e-291 901.0
CMS2_k127_5649833_30 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K13818 - 2.7.7.77 0.00000000000000000000000000000000000000000005548 167.0
CMS2_k127_5649833_31 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000003445 149.0
CMS2_k127_5649833_32 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000001966 147.0
CMS2_k127_5649833_33 RDD family - - - 0.00000000000000000000000000000000002817 140.0
CMS2_k127_5649833_34 Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000002264 141.0
CMS2_k127_5649833_35 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000008615 130.0
CMS2_k127_5649833_36 - - - - 0.00000000000000000000000005013 116.0
CMS2_k127_5649833_37 DNA polymerase III chi subunit K02339 GO:0005575,GO:0005622,GO:0005623,GO:0006275,GO:0008150,GO:0009314,GO:0009360,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0032991,GO:0042575,GO:0043846,GO:0043847,GO:0044424,GO:0044464,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:0090329,GO:1902494,GO:1990234,GO:2000105,GO:2000112 2.7.7.7 0.00000000000000001046 89.0
CMS2_k127_5649833_4 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 7.636e-267 828.0
CMS2_k127_5649833_5 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 7.583e-249 777.0
CMS2_k127_5649833_6 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 3.001e-244 794.0
CMS2_k127_5649833_7 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1 1.182e-202 642.0
CMS2_k127_5649833_8 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 588.0
CMS2_k127_5649833_9 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 569.0
CMS2_k127_5667316_0 Histidine kinase K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 431.0
CMS2_k127_5667316_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 314.0
CMS2_k127_5667316_2 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000003243 122.0
CMS2_k127_5667316_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000124 119.0
CMS2_k127_5863342_0 PFAM Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 316.0
CMS2_k127_5863342_1 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009661 259.0
CMS2_k127_5863342_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000003383 204.0
CMS2_k127_5863342_3 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.0000000000000000000000000000000001032 137.0
CMS2_k127_5863342_4 Sporulation related domain K03112 GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367 - 0.00001942 54.0
CMS2_k127_5906820_0 kinase domain - - - 7.709e-280 870.0
CMS2_k127_5906820_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.216e-254 796.0
CMS2_k127_5906820_10 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009087 254.0
CMS2_k127_5906820_11 Cyanate lyase C-terminal domain, Cyanate hydratase K01725 - 4.2.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000386 252.0
CMS2_k127_5906820_12 - - - - 0.000000000000000000000000000000000000000000000001075 177.0
CMS2_k127_5906820_13 DoxX family K15977 - - 0.0000000000000000000000000000000000000000000007672 170.0
CMS2_k127_5906820_14 transcriptional regulator - - - 0.000000000000000000000000000000000000000005436 160.0
CMS2_k127_5906820_15 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000283 153.0
CMS2_k127_5906820_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000002906 151.0
CMS2_k127_5906820_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000003153 145.0
CMS2_k127_5906820_18 PFAM response regulator receiver K14987 - - 0.0000000000000000000000000003881 117.0
CMS2_k127_5906820_19 - - - - 0.0000000125 61.0
CMS2_k127_5906820_2 Conserved region in glutamate synthase - - - 2.978e-220 693.0
CMS2_k127_5906820_3 belongs to the aldehyde dehydrogenase family K00128,K06447 - 1.2.1.3,1.2.1.71 3.934e-210 662.0
CMS2_k127_5906820_4 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 546.0
CMS2_k127_5906820_5 PFAM Formate nitrite transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 434.0
CMS2_k127_5906820_6 COG1131 ABC-type multidrug transport system, ATPase component K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 415.0
CMS2_k127_5906820_7 Belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 406.0
CMS2_k127_5906820_8 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 347.0
CMS2_k127_5906820_9 protein conserved in bacteria K09929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 283.0
CMS2_k127_6099275_0 response regulator receiver K02487,K06596 - - 5.212e-266 850.0
CMS2_k127_6099275_1 reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 347.0
CMS2_k127_6099275_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000005301 227.0
CMS2_k127_6099275_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000009847 118.0
CMS2_k127_6099275_4 CheW-like domain K06598 - - 0.0000000000008904 74.0
CMS2_k127_6109423_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 565.0
CMS2_k127_6109423_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 272.0
CMS2_k127_6109423_2 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000001868 231.0
CMS2_k127_6111163_0 TIGRFAM cytochrome c oxidase accessory protein FixG - - - 1.631e-202 639.0
CMS2_k127_6111163_1 FixH family K09926 - - 0.000000000000000000000002177 108.0
CMS2_k127_6111163_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000002153 84.0
CMS2_k127_6135720_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 1.839e-213 671.0
CMS2_k127_6135720_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 548.0
CMS2_k127_6135720_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 364.0
CMS2_k127_6135720_3 Phosphonate ABC transporter, periplasmic K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001788 289.0
CMS2_k127_6135720_4 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000006504 235.0
CMS2_k127_6135720_5 Histidine kinase - - - 0.00000000000000000000000000000000000001977 147.0
CMS2_k127_6135720_7 His Kinase A (phosphoacceptor) domain - - - 0.00000009561 53.0
CMS2_k127_6143949_0 Phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 334.0
CMS2_k127_6143949_1 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000002737 186.0
CMS2_k127_6143949_2 - K09004 - - 0.000000000000000000000000000000000000000919 153.0
CMS2_k127_6143949_3 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000001758 153.0
CMS2_k127_6143949_4 AntiSigma factor - - - 0.0000000000000000000000009253 113.0
CMS2_k127_6143949_5 Putative zinc- or iron-chelating domain K06940 - - 0.00000008033 55.0
CMS2_k127_6170403_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1161.0
CMS2_k127_6170403_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1131.0
CMS2_k127_6170403_10 Cytochrome c-type biogenesis protein Ccs1 ResB K07399 - - 1.021e-204 656.0
CMS2_k127_6170403_11 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 1.876e-201 635.0
CMS2_k127_6170403_12 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009156 605.0
CMS2_k127_6170403_13 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 586.0
CMS2_k127_6170403_14 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 575.0
CMS2_k127_6170403_15 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 562.0
CMS2_k127_6170403_16 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 535.0
CMS2_k127_6170403_17 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 533.0
CMS2_k127_6170403_18 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 521.0
CMS2_k127_6170403_19 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 453.0
CMS2_k127_6170403_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.182e-293 913.0
CMS2_k127_6170403_20 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 418.0
CMS2_k127_6170403_21 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 409.0
CMS2_k127_6170403_22 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 409.0
CMS2_k127_6170403_23 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 399.0
CMS2_k127_6170403_24 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 369.0
CMS2_k127_6170403_25 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 365.0
CMS2_k127_6170403_26 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 384.0
CMS2_k127_6170403_27 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 350.0
CMS2_k127_6170403_28 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 359.0
CMS2_k127_6170403_29 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 357.0
CMS2_k127_6170403_3 PFAM UvrD REP helicase K03657 - 3.6.4.12 3.232e-291 910.0
CMS2_k127_6170403_30 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 366.0
CMS2_k127_6170403_31 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 336.0
CMS2_k127_6170403_32 Double sensory domain of two-component sensor kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 351.0
CMS2_k127_6170403_33 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 331.0
CMS2_k127_6170403_34 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 327.0
CMS2_k127_6170403_35 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 323.0
CMS2_k127_6170403_36 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 337.0
CMS2_k127_6170403_37 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 325.0
CMS2_k127_6170403_38 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 293.0
CMS2_k127_6170403_39 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 299.0
CMS2_k127_6170403_4 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 4.595e-276 853.0
CMS2_k127_6170403_40 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 290.0
CMS2_k127_6170403_41 (ABC) transporter K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002939 282.0
CMS2_k127_6170403_42 Proteasome subunit K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006648 277.0
CMS2_k127_6170403_43 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001028 275.0
CMS2_k127_6170403_44 Periplasmic binding proteins and sugar binding domain of LacI family K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006338 271.0
CMS2_k127_6170403_45 Response regulator of the LytR AlgR family K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001483 263.0
CMS2_k127_6170403_46 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003046 259.0
CMS2_k127_6170403_47 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004012 251.0
CMS2_k127_6170403_48 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000001515 242.0
CMS2_k127_6170403_49 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K03796 - - 0.0000000000000000000000000000000000000000000000000000000000000000001869 237.0
CMS2_k127_6170403_5 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 1.352e-262 820.0
CMS2_k127_6170403_50 enzyme of heme biosynthesis K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000002121 241.0
CMS2_k127_6170403_51 TIGRFAM Diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000002631 250.0
CMS2_k127_6170403_52 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000000000000000000000000000001889 229.0
CMS2_k127_6170403_53 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000000000000000000001003 232.0
CMS2_k127_6170403_54 COG2863 Cytochrome c553 - - - 0.0000000000000000000000000000000000000000000000000000000000000002306 226.0
CMS2_k127_6170403_55 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000009442 227.0
CMS2_k127_6170403_56 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000261 212.0
CMS2_k127_6170403_57 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000003857 203.0
CMS2_k127_6170403_58 Domain of unknown function (DUF3393) - - - 0.00000000000000000000000000000000000000000000000000000007246 211.0
CMS2_k127_6170403_59 Nucleoside recognition K06373 - - 0.0000000000000000000000000000000000000000000000000000002147 204.0
CMS2_k127_6170403_6 peptidase K01414 - 3.4.24.70 6.007e-245 775.0
CMS2_k127_6170403_60 Nucleoside recognition K06374 - - 0.0000000000000000000000000000000000000000000000000000002666 198.0
CMS2_k127_6170403_61 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000003039 200.0
CMS2_k127_6170403_62 Sterol-binding domain protein K03690 - - 0.00000000000000000000000000000000000000000000000008338 185.0
CMS2_k127_6170403_63 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000002031 184.0
CMS2_k127_6170403_64 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000005394 174.0
CMS2_k127_6170403_65 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000001432 176.0
CMS2_k127_6170403_66 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000003901 166.0
CMS2_k127_6170403_67 LPP20 lipoprotein - - - 0.000000000000000000000000000000000000000004167 161.0
CMS2_k127_6170403_68 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000000000000000000000002402 155.0
CMS2_k127_6170403_69 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000002405 165.0
CMS2_k127_6170403_7 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 3.228e-235 738.0
CMS2_k127_6170403_70 Lipoprotein - - - 0.000000000000000000000000000000000000002552 162.0
CMS2_k127_6170403_71 Uroporphyrinogen-III synthase K01719 GO:0003674,GO:0003824,GO:0004852,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.75 0.00000000000000000000000000000000000008881 152.0
CMS2_k127_6170403_72 peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000003081 143.0
CMS2_k127_6170403_73 cheY-homologous receiver domain K02657,K03413 - - 0.000000000000000000000000000000388 125.0
CMS2_k127_6170403_74 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000002189 138.0
CMS2_k127_6170403_75 sulfur carrier activity K04085 - - 0.000000000000000000000000000006247 119.0
CMS2_k127_6170403_76 - - - - 0.000000000000000000000000000007594 121.0
CMS2_k127_6170403_77 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000001648 114.0
CMS2_k127_6170403_78 Protein conserved in bacteria K09954 - - 0.000000000000000000000000001651 112.0
CMS2_k127_6170403_79 - - - - 0.000000000000000000000000001979 114.0
CMS2_k127_6170403_8 argininosuccinate lyase K01755 - 4.3.2.1 2.342e-228 714.0
CMS2_k127_6170403_80 Thioredoxin-like - - - 0.00000000000000000000000004073 114.0
CMS2_k127_6170403_82 Diguanylate cyclase - - - 0.000000000000000000000001047 105.0
CMS2_k127_6170403_83 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.000000000000000000000001429 109.0
CMS2_k127_6170403_84 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000000000007935 104.0
CMS2_k127_6170403_85 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000001609 113.0
CMS2_k127_6170403_86 - - - - 0.00000000000000000000004493 102.0
CMS2_k127_6170403_87 cheY-homologous receiver domain - - - 0.0000000000000000000001015 102.0
CMS2_k127_6170403_88 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000009472 91.0
CMS2_k127_6170403_89 - - - - 0.0000000000000006862 79.0
CMS2_k127_6170403_9 COG1593 TRAP-type C4-dicarboxylate transport system large permease component K11690 GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - 1.274e-211 664.0
CMS2_k127_6170403_90 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002548 73.0
CMS2_k127_6170403_91 Sulfatase-modifying factor enzyme 1 - - - 0.00000000001198 75.0
CMS2_k127_6170403_92 peptidyl-tyrosine sulfation - - - 0.00000000001736 75.0
CMS2_k127_6170403_93 - - - - 0.000007234 53.0
CMS2_k127_6189645_0 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 319.0
CMS2_k127_6189645_1 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000001243 202.0
CMS2_k127_6220579_0 PFAM ATP-grasp fold - - - 2.598e-202 641.0
CMS2_k127_6220579_1 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 552.0
CMS2_k127_6220579_10 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 366.0
CMS2_k127_6220579_11 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 332.0
CMS2_k127_6220579_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 324.0
CMS2_k127_6220579_13 TIGRFAM channel protein, hemolysin III family K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 314.0
CMS2_k127_6220579_14 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 302.0
CMS2_k127_6220579_15 YaeQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004232 276.0
CMS2_k127_6220579_16 PFAM Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004362 235.0
CMS2_k127_6220579_17 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000002888 224.0
CMS2_k127_6220579_19 - - - - 0.000000000000000000000000000000000000005979 158.0
CMS2_k127_6220579_2 COG1718 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 452.0
CMS2_k127_6220579_20 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000001571 150.0
CMS2_k127_6220579_21 - - - - 0.000000000000000000000000000000001576 130.0
CMS2_k127_6220579_22 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000000009164 121.0
CMS2_k127_6220579_23 DNA-binding protein VF530 - - - 0.000000000000000000000000001095 114.0
CMS2_k127_6220579_24 - - - - 0.000000000000000000000005308 105.0
CMS2_k127_6220579_25 - - - - 0.00000000000000000000008835 100.0
CMS2_k127_6220579_26 - - - - 0.0000000000000000000003952 98.0
CMS2_k127_6220579_27 proteasome regulatory particle assembly K15503,K15504 - - 0.00000000000000000004644 96.0
CMS2_k127_6220579_29 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000676 98.0
CMS2_k127_6220579_3 COG0456 Acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 451.0
CMS2_k127_6220579_31 - - - - 0.000000000000001686 85.0
CMS2_k127_6220579_32 - - - - 0.00000000002833 71.0
CMS2_k127_6220579_34 - - - - 0.00000009015 61.0
CMS2_k127_6220579_35 heat shock protein binding - - - 0.00003202 57.0
CMS2_k127_6220579_4 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 449.0
CMS2_k127_6220579_5 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 435.0
CMS2_k127_6220579_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 407.0
CMS2_k127_6220579_7 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 398.0
CMS2_k127_6220579_8 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 371.0
CMS2_k127_6220579_9 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 358.0
CMS2_k127_6229253_0 Heat shock 70 kDa protein K04043 - - 7.396e-278 865.0
CMS2_k127_6229253_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656,K03657 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 4.252e-249 785.0
CMS2_k127_6229253_10 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 496.0
CMS2_k127_6229253_11 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 498.0
CMS2_k127_6229253_12 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 482.0
CMS2_k127_6229253_13 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 480.0
CMS2_k127_6229253_14 PFAM Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 447.0
CMS2_k127_6229253_15 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 443.0
CMS2_k127_6229253_16 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 405.0
CMS2_k127_6229253_17 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 384.0
CMS2_k127_6229253_18 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 386.0
CMS2_k127_6229253_19 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 340.0
CMS2_k127_6229253_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 4.558e-246 766.0
CMS2_k127_6229253_20 Spermidine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 336.0
CMS2_k127_6229253_21 PFAM Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 342.0
CMS2_k127_6229253_22 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 336.0
CMS2_k127_6229253_23 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 340.0
CMS2_k127_6229253_24 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 338.0
CMS2_k127_6229253_25 Lytic murein transglycosylase K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 331.0
CMS2_k127_6229253_26 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 343.0
CMS2_k127_6229253_27 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 327.0
CMS2_k127_6229253_28 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 328.0
CMS2_k127_6229253_29 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 331.0
CMS2_k127_6229253_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 6.182e-236 737.0
CMS2_k127_6229253_30 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 308.0
CMS2_k127_6229253_31 1-aminocyclopropane-1-carboxylate deaminase K01505 - 3.5.99.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 311.0
CMS2_k127_6229253_32 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 289.0
CMS2_k127_6229253_33 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004149 284.0
CMS2_k127_6229253_34 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004426 290.0
CMS2_k127_6229253_35 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00966,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007589 277.0
CMS2_k127_6229253_36 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004386 268.0
CMS2_k127_6229253_37 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000006778 265.0
CMS2_k127_6229253_38 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000008515 263.0
CMS2_k127_6229253_39 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002761 243.0
CMS2_k127_6229253_4 inner membrane component K02011 - - 1.941e-224 707.0
CMS2_k127_6229253_40 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000001831 242.0
CMS2_k127_6229253_41 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002077 247.0
CMS2_k127_6229253_42 Responsible for synthesis of pseudouridine from uracil K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000005997 237.0
CMS2_k127_6229253_43 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000006526 239.0
CMS2_k127_6229253_44 N-acetylmuramoyl-L-alanine amidase K03806 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000008018 228.0
CMS2_k127_6229253_45 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000008485 227.0
CMS2_k127_6229253_46 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000005659 207.0
CMS2_k127_6229253_47 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000006131 199.0
CMS2_k127_6229253_48 - - - - 0.000000000000000000000000000000000000000000000000000004221 200.0
CMS2_k127_6229253_49 Cobalamin synthesis protein - - - 0.00000000000000000000000000000000000000000000000000196 195.0
CMS2_k127_6229253_5 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 7.773e-219 695.0
CMS2_k127_6229253_50 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000000000002294 201.0
CMS2_k127_6229253_51 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000005139 177.0
CMS2_k127_6229253_52 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000007157 169.0
CMS2_k127_6229253_53 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.00000000000000000000000000000000000000001669 158.0
CMS2_k127_6229253_54 - - - - 0.00000000000000000000000000000000000000006475 161.0
CMS2_k127_6229253_55 SMART Mov34 MPN PAD-1 family protein - - - 0.00000000000000000000000000000000001038 139.0
CMS2_k127_6229253_56 - - - - 0.00000000000000000000000000000000004225 139.0
CMS2_k127_6229253_57 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000009364 132.0
CMS2_k127_6229253_58 - - - - 0.00000000000000000000000000000000206 134.0
CMS2_k127_6229253_59 Response regulator receiver domain K02658 - - 0.000000000000000000000000000000008485 134.0
CMS2_k127_6229253_6 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 612.0
CMS2_k127_6229253_60 protein conserved in bacteria - - - 0.00000000000000000000000000003749 121.0
CMS2_k127_6229253_61 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000005384 124.0
CMS2_k127_6229253_62 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.1.10 0.00000000000000000000000003527 119.0
CMS2_k127_6229253_63 FecR protein - - - 0.000000000000000000000000102 116.0
CMS2_k127_6229253_64 - - - - 0.0000000000000000000000059 104.0
CMS2_k127_6229253_65 cell redox homeostasis - - - 0.0000000000000000000002154 102.0
CMS2_k127_6229253_66 Belongs to the UPF0250 family K09158 - - 0.000000000000000000004544 95.0
CMS2_k127_6229253_67 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 - 0.00000000000000000001153 99.0
CMS2_k127_6229253_68 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000002618 94.0
CMS2_k127_6229253_69 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000005136 94.0
CMS2_k127_6229253_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 570.0
CMS2_k127_6229253_70 SpoU rRNA Methylase family - - - 0.000000000000000001033 93.0
CMS2_k127_6229253_71 Sel1-like repeats. K07126 - - 0.0000000000000003072 90.0
CMS2_k127_6229253_72 - - - - 0.000000000000004398 85.0
CMS2_k127_6229253_73 - - - - 0.000000003586 64.0
CMS2_k127_6229253_74 PilZ domain - - - 0.0000001919 57.0
CMS2_k127_6229253_75 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.0000005189 53.0
CMS2_k127_6229253_76 - - - - 0.00001868 49.0
CMS2_k127_6229253_8 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 526.0
CMS2_k127_6229253_9 PFAM Type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 525.0
CMS2_k127_6246428_0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 439.0
CMS2_k127_6246428_1 Type VI secretion system protein DotU K11892 - - 0.00000000000000000000000000002173 126.0
CMS2_k127_6323754_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 0.0 1383.0
CMS2_k127_6323754_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1105.0
CMS2_k127_6323754_10 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008467 258.0
CMS2_k127_6323754_11 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002911 258.0
CMS2_k127_6323754_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000002824 226.0
CMS2_k127_6323754_13 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000004349 162.0
CMS2_k127_6323754_14 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000001437 145.0
CMS2_k127_6323754_15 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000005805 134.0
CMS2_k127_6323754_16 Uncharacterized ArCR, COG1888 K09732 - - 0.00000000000000000000000000000001792 128.0
CMS2_k127_6323754_17 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000000000002205 104.0
CMS2_k127_6323754_2 HypF finger - - - 2.25e-214 689.0
CMS2_k127_6323754_3 Hydrogenase formation hypA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 536.0
CMS2_k127_6323754_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 420.0
CMS2_k127_6323754_5 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 422.0
CMS2_k127_6323754_6 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 400.0
CMS2_k127_6323754_7 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 381.0
CMS2_k127_6323754_8 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 373.0
CMS2_k127_6323754_9 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 331.0
CMS2_k127_6351648_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1195.0
CMS2_k127_6351648_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1037.0
CMS2_k127_6351648_10 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 381.0
CMS2_k127_6351648_11 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 345.0
CMS2_k127_6351648_12 Aminotransferase class I and II K02225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 329.0
CMS2_k127_6351648_13 TIGRFAM Cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 297.0
CMS2_k127_6351648_14 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001215 282.0
CMS2_k127_6351648_15 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001341 287.0
CMS2_k127_6351648_16 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002382 277.0
CMS2_k127_6351648_17 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000005732 253.0
CMS2_k127_6351648_18 COG1145 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000002939 233.0
CMS2_k127_6351648_19 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000008854 225.0
CMS2_k127_6351648_2 ABC transporter - - - 5.613e-300 926.0
CMS2_k127_6351648_20 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000001459 211.0
CMS2_k127_6351648_21 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000002455 211.0
CMS2_k127_6351648_22 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000000101 200.0
CMS2_k127_6351648_23 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000001057 189.0
CMS2_k127_6351648_24 - - - - 0.0000000000000000000000000000000000000000000000001479 180.0
CMS2_k127_6351648_25 transmembrane transport K03442 - - 0.00000000000000000000000000000000000007902 148.0
CMS2_k127_6351648_26 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000004133 108.0
CMS2_k127_6351648_28 - - - - 0.0000000000000002848 79.0
CMS2_k127_6351648_29 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000001621 58.0
CMS2_k127_6351648_3 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.10 1.607e-210 665.0
CMS2_k127_6351648_30 HDOD domain K01915 - 6.3.1.2 0.00004733 48.0
CMS2_k127_6351648_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone - - - 2.352e-203 644.0
CMS2_k127_6351648_5 Glucose-1-phosphate adenylyltransferase K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 570.0
CMS2_k127_6351648_6 Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 572.0
CMS2_k127_6351648_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 552.0
CMS2_k127_6351648_8 COG4206 Outer membrane cobalamin receptor protein K16092 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 454.0
CMS2_k127_6351648_9 6-phosphogluconate dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 430.0
CMS2_k127_6376065_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1229.0
CMS2_k127_6376065_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 1.25e-314 981.0
CMS2_k127_6376065_10 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 509.0
CMS2_k127_6376065_11 binding-protein-dependent transport systems inner membrane component K13895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 491.0
CMS2_k127_6376065_12 double-strand break repair protein AddB K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 510.0
CMS2_k127_6376065_13 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 419.0
CMS2_k127_6376065_14 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 410.0
CMS2_k127_6376065_15 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 400.0
CMS2_k127_6376065_16 Protein of unknown function (DUF1538) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 374.0
CMS2_k127_6376065_17 Protein of unknown function (DUF1538) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 353.0
CMS2_k127_6376065_18 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 370.0
CMS2_k127_6376065_19 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 339.0
CMS2_k127_6376065_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.905e-297 919.0
CMS2_k127_6376065_20 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 342.0
CMS2_k127_6376065_21 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 319.0
CMS2_k127_6376065_22 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 303.0
CMS2_k127_6376065_23 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000006069 206.0
CMS2_k127_6376065_24 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000184 198.0
CMS2_k127_6376065_25 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000003246 196.0
CMS2_k127_6376065_26 CBS domain - - - 0.0000000000000000000000000000000000000000000000008165 177.0
CMS2_k127_6376065_27 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000494 176.0
CMS2_k127_6376065_28 membrane - - - 0.00000000000000000000000000000000000000000000002724 181.0
CMS2_k127_6376065_29 Belongs to the P(II) protein family - - - 0.0000000000000000000000000000000000000000000001527 170.0
CMS2_k127_6376065_3 transmembrane transport K02035,K13893 - - 7.491e-222 702.0
CMS2_k127_6376065_30 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000002728 139.0
CMS2_k127_6376065_31 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001395 124.0
CMS2_k127_6376065_32 - - - - 0.00000000000000000000000002592 108.0
CMS2_k127_6376065_33 - - - - 0.0000000000000000000000007308 107.0
CMS2_k127_6376065_36 Lysin motif - - - 0.000001451 61.0
CMS2_k127_6376065_37 - - - - 0.0001341 45.0
CMS2_k127_6376065_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 5.437e-212 664.0
CMS2_k127_6376065_5 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 3.725e-199 631.0
CMS2_k127_6376065_6 Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) K00209 - 1.3.1.44,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 581.0
CMS2_k127_6376065_7 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 573.0
CMS2_k127_6376065_8 COG0436 Aspartate tyrosine aromatic aminotransferase K00812,K12252 - 2.6.1.1,2.6.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 556.0
CMS2_k127_6376065_9 transport system, permease component K13894 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 505.0
CMS2_k127_6452629_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1461.0
CMS2_k127_6452629_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1158.0
CMS2_k127_6452629_10 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 7.028e-195 623.0
CMS2_k127_6452629_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 578.0
CMS2_k127_6452629_12 FAD linked oxidases, C-terminal domain K03777 - 1.1.5.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 577.0
CMS2_k127_6452629_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 559.0
CMS2_k127_6452629_14 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 547.0
CMS2_k127_6452629_15 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 552.0
CMS2_k127_6452629_16 Type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 514.0
CMS2_k127_6452629_17 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 486.0
CMS2_k127_6452629_18 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 489.0
CMS2_k127_6452629_19 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 478.0
CMS2_k127_6452629_2 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 7.763e-238 749.0
CMS2_k127_6452629_20 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 456.0
CMS2_k127_6452629_21 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 452.0
CMS2_k127_6452629_22 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 434.0
CMS2_k127_6452629_23 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 429.0
CMS2_k127_6452629_24 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 422.0
CMS2_k127_6452629_25 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 420.0
CMS2_k127_6452629_26 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 405.0
CMS2_k127_6452629_27 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 392.0
CMS2_k127_6452629_28 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 404.0
CMS2_k127_6452629_29 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 394.0
CMS2_k127_6452629_3 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 9.717e-222 692.0
CMS2_k127_6452629_30 Type IV leader peptidase family K02464,K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 369.0
CMS2_k127_6452629_31 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 368.0
CMS2_k127_6452629_32 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 365.0
CMS2_k127_6452629_33 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 353.0
CMS2_k127_6452629_34 PFAM LppC K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 353.0
CMS2_k127_6452629_35 Belongs to the peptidase S1C family K04691,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 339.0
CMS2_k127_6452629_36 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 329.0
CMS2_k127_6452629_37 ABC transporter permease K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 329.0
CMS2_k127_6452629_38 antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 329.0
CMS2_k127_6452629_39 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 326.0
CMS2_k127_6452629_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.263e-220 689.0
CMS2_k127_6452629_40 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 324.0
CMS2_k127_6452629_41 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 317.0
CMS2_k127_6452629_42 NIF3 (NGG1p interacting factor 3) - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 299.0
CMS2_k127_6452629_43 PFAM Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 293.0
CMS2_k127_6452629_44 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 296.0
CMS2_k127_6452629_45 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 282.0
CMS2_k127_6452629_46 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001894 278.0
CMS2_k127_6452629_47 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004871 282.0
CMS2_k127_6452629_48 COG0625 Glutathione S-transferase K03599 GO:0001000,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0008150,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0042594,GO:0043175,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001281 274.0
CMS2_k127_6452629_49 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271,K12961 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004383 268.0
CMS2_k127_6452629_5 Cysteine-rich domain - - - 3.52e-219 687.0
CMS2_k127_6452629_50 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000002109 260.0
CMS2_k127_6452629_51 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008533 241.0
CMS2_k127_6452629_52 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000001717 231.0
CMS2_k127_6452629_53 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000002147 202.0
CMS2_k127_6452629_54 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000002395 213.0
CMS2_k127_6452629_55 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000002289 196.0
CMS2_k127_6452629_56 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000001865 186.0
CMS2_k127_6452629_57 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000002962 188.0
CMS2_k127_6452629_58 toluene tolerance family protein K07323 - - 0.00000000000000000000000000000000000000000000000003154 185.0
CMS2_k127_6452629_59 MlaD protein K02067 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008289,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000003903 184.0
CMS2_k127_6452629_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 5.664e-207 650.0
CMS2_k127_6452629_60 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins K21218 - - 0.0000000000000000000000000000000000000000001172 171.0
CMS2_k127_6452629_61 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000003512 164.0
CMS2_k127_6452629_62 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000004877 156.0
CMS2_k127_6452629_63 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000001875 154.0
CMS2_k127_6452629_64 Sigma 54 modulation protein K05808 - - 0.00000000000000000000000000000000000008333 144.0
CMS2_k127_6452629_65 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000005415 147.0
CMS2_k127_6452629_66 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 - 0.0000000000000000000000000000000001958 137.0
CMS2_k127_6452629_67 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.000000000000000000000000007834 114.0
CMS2_k127_6452629_68 - - - - 0.00000000000000000000000002247 113.0
CMS2_k127_6452629_69 Phosphocarrier protein HPr K08485,K11189 - - 0.00000000000000000000000002487 111.0
CMS2_k127_6452629_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 5.678e-207 649.0
CMS2_k127_6452629_70 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000002152 110.0
CMS2_k127_6452629_71 LppC putative lipoprotein - - - 0.0000000000000000000002328 98.0
CMS2_k127_6452629_72 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000003835 89.0
CMS2_k127_6452629_73 - - - - 0.0000000000000000004492 87.0
CMS2_k127_6452629_74 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.0000000000000006814 85.0
CMS2_k127_6452629_76 - - - - 0.000000000006623 65.0
CMS2_k127_6452629_77 NTP binding protein (Contains STAS domain) K07122 - - 0.00000000006513 66.0
CMS2_k127_6452629_78 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000006677 70.0
CMS2_k127_6452629_79 - - - - 0.00000002131 61.0
CMS2_k127_6452629_8 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 6.092e-200 629.0
CMS2_k127_6452629_80 Protein conserved in bacteria - - - 0.00001422 53.0
CMS2_k127_6452629_9 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.072e-199 632.0
CMS2_k127_6467791_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 3.714e-318 979.0
CMS2_k127_6467791_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 7.469e-237 740.0
CMS2_k127_6467791_10 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.00000000000000000000000000000000000000000000000004819 179.0
CMS2_k127_6467791_11 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000000000000000001284 174.0
CMS2_k127_6467791_12 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.00000000000000000000000000000000000000000000197 166.0
CMS2_k127_6467791_13 High-affinity nickel-transport protein - - - 0.000000000000000000000001338 112.0
CMS2_k127_6467791_14 Domain of unknown function (DUF4124) - - - 0.00000000001785 71.0
CMS2_k127_6467791_2 response regulator K07712 - - 1.958e-207 654.0
CMS2_k127_6467791_3 signal transduction histidine kinase K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 385.0
CMS2_k127_6467791_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 369.0
CMS2_k127_6467791_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 357.0
CMS2_k127_6467791_6 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 357.0
CMS2_k127_6467791_7 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 338.0
CMS2_k127_6467791_8 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003198 251.0
CMS2_k127_6467791_9 UreD urease accessory protein K03190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004408 246.0
CMS2_k127_6490248_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 411.0
CMS2_k127_6490248_1 epimerase dehydratase K02473,K08679 - 5.1.3.6,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 401.0
CMS2_k127_6536399_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 1.052e-273 854.0
CMS2_k127_6536399_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 559.0
CMS2_k127_6536399_10 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000003726 154.0
CMS2_k127_6536399_11 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000004077 145.0
CMS2_k127_6536399_12 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.0000000000000000000000000004418 113.0
CMS2_k127_6536399_13 protein conserved in bacteria K15539 - - 0.00000000000000000001275 103.0
CMS2_k127_6536399_14 Bacterial protein of unknown function (DUF945) - - - 0.0002548 53.0
CMS2_k127_6536399_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 543.0
CMS2_k127_6536399_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 466.0
CMS2_k127_6536399_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006834 277.0
CMS2_k127_6536399_5 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000046 229.0
CMS2_k127_6536399_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000001479 226.0
CMS2_k127_6536399_7 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000000000000000000000001541 201.0
CMS2_k127_6536399_8 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 - - 0.00000000000000000000000000000000000000000000001696 172.0
CMS2_k127_6536399_9 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.000000000000000000000000000000000000000000002265 173.0
CMS2_k127_6553900_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K03406 - - 0.000000000000000000000000000000000000000000000000000000001091 218.0
CMS2_k127_6553900_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000004827 130.0
CMS2_k127_6661544_0 Histidine kinase - - - 3.424e-237 762.0
CMS2_k127_6661544_1 PFAM metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000001983 244.0
CMS2_k127_6661544_2 - - - - 0.0000000000000000000000000000000000000000000000000000008117 199.0
CMS2_k127_6661544_3 Spermidine putrescine-binding periplasmic protein K02055 - - 0.000000000000000002523 84.0
CMS2_k127_6661544_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000001934 68.0
CMS2_k127_6789980_0 Belongs to the peptidase S11 family K07258 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 469.0
CMS2_k127_6789980_1 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 305.0
CMS2_k127_6789980_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000001242 112.0
CMS2_k127_7029006_0 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 8.898e-273 841.0
CMS2_k127_7029006_1 Nitrogenase component 1 type Oxidoreductase K02587 - - 6.162e-254 789.0
CMS2_k127_7029006_10 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000009163 196.0
CMS2_k127_7029006_11 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000001117 166.0
CMS2_k127_7029006_12 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000001144 161.0
CMS2_k127_7029006_13 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000000005834 156.0
CMS2_k127_7029006_14 PFAM Dinitrogenase iron-molybdenum cofactor K02596 - - 0.00000000000000000000000000000007282 128.0
CMS2_k127_7029006_15 PFAM NifT FixU K02593 - - 0.000000000000000000000000000004882 119.0
CMS2_k127_7029006_16 PFAM 4Fe-4S binding domain - - - 0.000000000000000000000000002051 111.0
CMS2_k127_7029006_17 Protein of unknown function (DUF3144) - - - 0.0000000000000000000000463 100.0
CMS2_k127_7029006_18 COG3209 Rhs family protein - - - 0.00000000000000000000007094 100.0
CMS2_k127_7029006_19 - - - - 0.00000000000000000000147 98.0
CMS2_k127_7029006_2 Belongs to the NifD NifK NifE NifN family K02592 - - 2.987e-217 682.0
CMS2_k127_7029006_20 Belongs to the BolA IbaG family - - - 0.00000000000000000004174 92.0
CMS2_k127_7029006_21 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide K02439 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016740,GO:0016782,GO:0016783,GO:0044424,GO:0044464 2.8.1.1 0.00000000000000001974 86.0
CMS2_k127_7029006_22 - - - - 0.00000000000000009452 85.0
CMS2_k127_7029006_23 - - - - 0.0000000001837 65.0
CMS2_k127_7029006_3 Dinitrogenase iron-molybdenum cofactor, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 309.0
CMS2_k127_7029006_4 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 301.0
CMS2_k127_7029006_5 Glycosyl transferase family, helical bundle domain - GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 305.0
CMS2_k127_7029006_6 LRV protein FeS4 cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 291.0
CMS2_k127_7029006_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002832 282.0
CMS2_k127_7029006_8 PFAM Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001114 278.0
CMS2_k127_7029006_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002498 269.0
CMS2_k127_7041431_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002935 282.0
CMS2_k127_7041431_1 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000005517 174.0
CMS2_k127_7041431_2 Transposase IS200 like - - - 0.00000000000000000000000000000000000007409 143.0
CMS2_k127_7041431_3 Transposase IS200 like K07491 - - 0.00000001187 57.0
CMS2_k127_7041431_4 Transposase IS200 like - - - 0.000002178 49.0
CMS2_k127_7041431_5 PEP-CTERM motif - - - 0.000004944 56.0
CMS2_k127_704795_0 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 0.0 1017.0
CMS2_k127_704795_1 COG3901 Regulator of nitric oxide reductase transcription K19339 - - 6.461e-249 785.0
CMS2_k127_704795_10 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 314.0
CMS2_k127_704795_11 ABC transporter K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 306.0
CMS2_k127_704795_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 287.0
CMS2_k127_704795_13 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000101 278.0
CMS2_k127_704795_14 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000107 274.0
CMS2_k127_704795_15 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006221 258.0
CMS2_k127_704795_16 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000003139 209.0
CMS2_k127_704795_17 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000006975 170.0
CMS2_k127_704795_18 NosL K19342 - - 0.00000000000000000000000000000000000000000001137 167.0
CMS2_k127_704795_19 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000002088 151.0
CMS2_k127_704795_2 PFAM binding-protein-dependent transport systems inner membrane component K02037 - - 2.286e-224 717.0
CMS2_k127_704795_20 PAP2 superfamily - - - 0.000000000000000000000000000000000000003317 156.0
CMS2_k127_704795_3 Phosphate transport system permease protein K02038 - - 1.781e-211 670.0
CMS2_k127_704795_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 512.0
CMS2_k127_704795_5 Phosphate-binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 469.0
CMS2_k127_704795_6 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 472.0
CMS2_k127_704795_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009176 443.0
CMS2_k127_704795_8 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 350.0
CMS2_k127_704795_9 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 331.0
CMS2_k127_957341_0 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 500.0
CMS2_k127_957341_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 477.0
CMS2_k127_957341_2 Toxic anion resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 415.0
CMS2_k127_957341_3 - - - - 0.000000000000000000000000000000000000000000000000000000007918 208.0
CMS2_k127_957341_4 PFAM Methyltransferase type - - - 0.0000000000000000000000000000000000000000000007707 168.0
CMS2_k127_957341_5 - - - - 0.000002141 53.0