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Overview

ID MAG00454
Name CMS2_bin.68
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family SM23-35
Genus
Species
Assembly information
Completeness (%) 85.04
Contamination (%) 4.13
GC content (%) 47.0
N50 (bp) 7,216
Genome size (bp) 1,793,053

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1809

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1035345_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 455.0
CMS2_k127_1035345_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 312.0
CMS2_k127_1035345_2 Aminotransferase class I and II K14261 - - 0.00000934 48.0
CMS2_k127_1039693_0 spermidine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 502.0
CMS2_k127_1039693_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 289.0
CMS2_k127_1039693_2 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001746 275.0
CMS2_k127_1039693_3 ATP cone domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001388 231.0
CMS2_k127_1039693_4 molybdopterin synthase activity K03635,K03752 - 2.7.7.77,2.8.1.12 0.00000000000000000000000000000000000009137 144.0
CMS2_k127_1039693_5 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000000002619 93.0
CMS2_k127_1039693_6 - - - - 0.00000000000001116 76.0
CMS2_k127_1039693_7 Sporulation related domain K03749 - - 0.0003873 51.0
CMS2_k127_1114631_0 ABC transporter K06158 - - 4.196e-233 736.0
CMS2_k127_1114631_1 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 541.0
CMS2_k127_1114631_2 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 413.0
CMS2_k127_1114631_3 RHS Repeat - - - 0.00000000000000000000000000000000000009367 150.0
CMS2_k127_1114631_4 PFAM Transposase - - - 0.00000000000000000000000003405 113.0
CMS2_k127_1114631_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000001203 82.0
CMS2_k127_1139288_0 Aldehyde dehydrogenase family K00131 - 1.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 542.0
CMS2_k127_1139288_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000573 275.0
CMS2_k127_1139288_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000001303 224.0
CMS2_k127_1184435_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000008698 269.0
CMS2_k127_1184435_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000001675 124.0
CMS2_k127_1184435_2 - - - - 0.00000000000000000000006354 105.0
CMS2_k127_1197432_0 Fructose-bisphosphate aldolase class-II - - - 5.772e-198 626.0
CMS2_k127_1197432_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.000000000000000000000002244 104.0
CMS2_k127_1198530_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 598.0
CMS2_k127_1198530_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 606.0
CMS2_k127_1198530_2 regulation of single-species biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 349.0
CMS2_k127_1198530_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000001593 237.0
CMS2_k127_1198530_4 GYD domain - - - 0.0000000000000000000000000000000000001608 143.0
CMS2_k127_1198530_5 ORF6N domain - - - 0.000000000000000000000000000000004856 130.0
CMS2_k127_1198530_6 - - - - 0.0000000000000167 75.0
CMS2_k127_1198530_7 DNA/RNA hybrid annealing activity K07012,K19123 GO:0000014,GO:0000287,GO:0000737,GO:0000738,GO:0002252,GO:0002376,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0008296,GO:0008408,GO:0009056,GO:0009057,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017111,GO:0019439,GO:0033677,GO:0033680,GO:0034641,GO:0034655,GO:0042623,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0070035,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0097098,GO:0097159,GO:0097617,GO:0098542,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.00000000000009024 72.0
CMS2_k127_1198530_8 TIGRFAM CRISPR-associated helicase Cas3 K07012 - - 0.0001199 44.0
CMS2_k127_1198530_9 - - - - 0.000222 48.0
CMS2_k127_1225233_0 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 361.0
CMS2_k127_1225233_1 nitrogen compound transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002861 274.0
CMS2_k127_1225233_2 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000002592 251.0
CMS2_k127_1225233_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004711 249.0
CMS2_k127_1225233_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000001744 140.0
CMS2_k127_1225233_5 Cysteine-rich domain - - - 0.00000000000000000000001755 104.0
CMS2_k127_1225233_6 - - - - 0.00000000166 68.0
CMS2_k127_1225233_7 Cysteine-rich domain - - - 0.000001495 49.0
CMS2_k127_1245350_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000013 289.0
CMS2_k127_1245350_1 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 282.0
CMS2_k127_1245350_2 Nucleotide binding protein, PINc - - - 0.00000000000000000000000000001965 121.0
CMS2_k127_1245350_4 TIGRFAM parallel beta-helix repeat (two copies) - - - 0.000005463 53.0
CMS2_k127_1262215_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 580.0
CMS2_k127_1262215_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 388.0
CMS2_k127_1262215_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 300.0
CMS2_k127_1262215_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000003118 136.0
CMS2_k127_1262215_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000006562 134.0
CMS2_k127_1262215_5 cheY-homologous receiver domain - - - 0.00000000000000000000000003726 112.0
CMS2_k127_1262215_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000005824 94.0
CMS2_k127_1262215_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000788 84.0
CMS2_k127_1301924_0 glutamate synthase alpha subunit domain protein K00265 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 506.0
CMS2_k127_1301924_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 437.0
CMS2_k127_1301924_2 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000006579 147.0
CMS2_k127_1301924_3 nickel cation binding K04651,K19640 - - 0.0000000000000000000000000000007836 125.0
CMS2_k127_1301924_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000001509 115.0
CMS2_k127_1325917_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 376.0
CMS2_k127_1325917_1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000000003534 220.0
CMS2_k127_1325917_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000001101 205.0
CMS2_k127_1396167_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 474.0
CMS2_k127_1396167_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 317.0
CMS2_k127_1396167_2 HNH nucleases - - - 0.000000000000000000000000000000000000000019 156.0
CMS2_k127_1396167_3 - - - - 0.000000000000000000000006119 104.0
CMS2_k127_1396167_4 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.0000000000000003609 79.0
CMS2_k127_1396167_5 Acyl-transferase K00655 - 2.3.1.51 0.000000000000006658 85.0
CMS2_k127_140140_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 473.0
CMS2_k127_140140_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 329.0
CMS2_k127_140140_10 SpoVT / AbrB like domain - - - 0.000000000000000001164 87.0
CMS2_k127_140140_11 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000703 83.0
CMS2_k127_140140_12 PFAM Radical SAM - - - 0.000000000005566 67.0
CMS2_k127_140140_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001814 273.0
CMS2_k127_140140_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009786 261.0
CMS2_k127_140140_4 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000000001568 224.0
CMS2_k127_140140_5 Histidine kinase K13040 - 2.7.13.3 0.0000000000000000000000000000000000000000000000005267 196.0
CMS2_k127_140140_6 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000000000000000000000000000000119 178.0
CMS2_k127_140140_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000002513 171.0
CMS2_k127_140140_8 PFAM S23 ribosomal protein - - - 0.000000000000000000000000000000004058 131.0
CMS2_k127_140140_9 YGGT family K02221 - - 0.00000000000000000000000000000002058 129.0
CMS2_k127_147303_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 364.0
CMS2_k127_147303_1 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000003329 222.0
CMS2_k127_147303_2 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000000000000001832 208.0
CMS2_k127_147303_3 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000004254 181.0
CMS2_k127_147303_4 Membrane - - - 0.0000000000000000000000001393 117.0
CMS2_k127_147303_5 Type IV minor pilin ComP, DNA uptake sequence receptor K02650 - - 0.0000000003186 66.0
CMS2_k127_147303_6 Tetratricopeptide repeat - - - 0.00000005374 61.0
CMS2_k127_147303_7 Belongs to the N-Me-Phe pilin family K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.000000513 59.0
CMS2_k127_147303_8 nucleoside hydrolase - - - 0.000002079 63.0
CMS2_k127_1474516_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 302.0
CMS2_k127_1474516_1 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005084 242.0
CMS2_k127_1474516_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000001235 183.0
CMS2_k127_1474516_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000001981 130.0
CMS2_k127_1519778_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 421.0
CMS2_k127_1519778_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 356.0
CMS2_k127_1519778_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 340.0
CMS2_k127_1519778_3 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000007536 194.0
CMS2_k127_1519778_4 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000002066 150.0
CMS2_k127_1519778_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000009227 93.0
CMS2_k127_1522915_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 505.0
CMS2_k127_1522915_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 401.0
CMS2_k127_1522915_10 arsenite transmembrane transporter activity - - - 0.00000001996 57.0
CMS2_k127_1522915_2 LysM domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 321.0
CMS2_k127_1522915_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 291.0
CMS2_k127_1522915_4 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000005935 221.0
CMS2_k127_1522915_5 Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000005447 211.0
CMS2_k127_1522915_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000005579 156.0
CMS2_k127_1522915_7 TOBE domain K02019 - - 0.0000000000000000000000007634 107.0
CMS2_k127_1545273_0 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 2.798e-227 721.0
CMS2_k127_1545273_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 593.0
CMS2_k127_1545273_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 473.0
CMS2_k127_1545273_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 439.0
CMS2_k127_1545273_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00000000000000000000000000000000000000000000000000000939 196.0
CMS2_k127_1545273_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000001129 173.0
CMS2_k127_1545273_6 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000004886 136.0
CMS2_k127_1545273_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000009789 126.0
CMS2_k127_1545273_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000003375 117.0
CMS2_k127_1545273_9 PFAM Acetyltransferase (GNAT) family K03824 - - 0.00000001842 56.0
CMS2_k127_1551409_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 2.355e-221 695.0
CMS2_k127_1551409_1 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 587.0
CMS2_k127_1551409_2 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 540.0
CMS2_k127_1551409_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 412.0
CMS2_k127_1551409_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000018 202.0
CMS2_k127_1551409_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000005895 195.0
CMS2_k127_1551409_6 chemotaxis K03406 - - 0.00000000000000000000000000000000000000000001417 184.0
CMS2_k127_1551409_7 Sulfurtransferase TusA - - - 0.0000000000000000000000000004554 114.0
CMS2_k127_1551409_8 Domain of unknown function DUF11 - - - 0.000000000000003959 87.0
CMS2_k127_1556457_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 349.0
CMS2_k127_1556457_1 - - - - 0.00000000000000000000000000000000000000000000000000000000001746 209.0
CMS2_k127_1556457_2 - - - - 0.00000000000000000000000000000000000000003334 158.0
CMS2_k127_1556457_3 Transcriptional regulator - - - 0.000000000001965 68.0
CMS2_k127_1556792_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 507.0
CMS2_k127_1556792_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000008595 152.0
CMS2_k127_159279_0 B3/4 domain K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 475.0
CMS2_k127_159279_1 Protein of unknown function DUF72 - - - 0.000005121 49.0
CMS2_k127_1617395_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 560.0
CMS2_k127_1617395_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 474.0
CMS2_k127_1617395_2 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 415.0
CMS2_k127_1617395_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 364.0
CMS2_k127_1617395_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 358.0
CMS2_k127_1617395_5 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000002145 234.0
CMS2_k127_1617395_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000004526 190.0
CMS2_k127_1633950_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003315 258.0
CMS2_k127_1633950_1 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000005576 230.0
CMS2_k127_1633950_2 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000000000000000000000000000002322 180.0
CMS2_k127_1633950_3 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000001323 159.0
CMS2_k127_1633950_4 Thioredoxin - - - 0.000000000000000000000000000000000000002518 151.0
CMS2_k127_1633950_6 PilT protein domain protein - - - 0.000000000000001139 81.0
CMS2_k127_1633950_8 toxin-antitoxin pair type II binding - - - 0.0003054 47.0
CMS2_k127_1664603_0 Protein of unknown function, DUF255 K06888 - - 1.163e-251 794.0
CMS2_k127_1664603_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000009478 246.0
CMS2_k127_1664603_2 DsrC like protein K11179 - - 0.0000000000000000000000000000000000002832 143.0
CMS2_k127_1699131_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000001947 251.0
CMS2_k127_1699131_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000007242 79.0
CMS2_k127_1720167_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 583.0
CMS2_k127_1720167_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 319.0
CMS2_k127_1720167_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 305.0
CMS2_k127_1720167_3 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008266 285.0
CMS2_k127_1732140_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 370.0
CMS2_k127_1732140_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000008683 239.0
CMS2_k127_1732140_2 Protein of unknown function (DUF1318) - - - 0.00000000000000000000000000000000000000000002749 168.0
CMS2_k127_1732140_3 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000002135 175.0
CMS2_k127_1744478_0 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 458.0
CMS2_k127_1744478_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 355.0
CMS2_k127_1744478_2 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 350.0
CMS2_k127_1744478_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000002439 163.0
CMS2_k127_1744478_5 - - - - 0.0000005834 52.0
CMS2_k127_1745961_0 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000005201 264.0
CMS2_k127_1745961_1 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000127 102.0
CMS2_k127_1793796_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.935e-304 946.0
CMS2_k127_1793796_1 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 3.189e-226 716.0
CMS2_k127_1793796_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 556.0
CMS2_k127_1793796_3 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000001698 143.0
CMS2_k127_1793796_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000001371 51.0
CMS2_k127_1827465_0 Dehydratase family K01687 - 4.2.1.9 2.949e-263 820.0
CMS2_k127_1827465_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 598.0
CMS2_k127_1827465_2 Protein of unknown function (DUF2283) - - - 0.00000000000000000000000008827 111.0
CMS2_k127_1827465_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000008478 87.0
CMS2_k127_1827465_4 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000258 84.0
CMS2_k127_1925933_0 lactate metabolic process - - - 2.362e-285 883.0
CMS2_k127_1925933_1 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 449.0
CMS2_k127_1925933_2 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 366.0
CMS2_k127_1925933_3 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000003689 190.0
CMS2_k127_1925933_4 - - - - 0.00000000000000000000000000000000000000000000000001295 183.0
CMS2_k127_1925933_5 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000338 174.0
CMS2_k127_1925933_6 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000007912 123.0
CMS2_k127_1925933_7 Polysulphide reductase, NrfD K00185 - - 0.00000000000000077 77.0
CMS2_k127_1936869_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 494.0
CMS2_k127_1936869_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 391.0
CMS2_k127_1936869_2 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000008733 119.0
CMS2_k127_1945391_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1185.0
CMS2_k127_1945391_1 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005754 281.0
CMS2_k127_1945391_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001038 270.0
CMS2_k127_1945391_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000033 196.0
CMS2_k127_1945391_4 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000000000000000000000000000000004562 186.0
CMS2_k127_1945391_5 Polymer-forming cytoskeletal - - - 0.00000000000000001233 87.0
CMS2_k127_1945391_6 Peptidase family M23 - - - 0.0000000000000266 73.0
CMS2_k127_1953387_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0 1014.0
CMS2_k127_1953387_1 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 9.628e-275 863.0
CMS2_k127_1953387_2 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 526.0
CMS2_k127_1953387_3 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 390.0
CMS2_k127_1953387_4 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000002941 250.0
CMS2_k127_1953387_5 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000003889 210.0
CMS2_k127_1953387_6 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.0000000000000000003478 89.0
CMS2_k127_1982241_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 8.484e-250 781.0
CMS2_k127_1982241_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 336.0
CMS2_k127_1985166_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 469.0
CMS2_k127_2011372_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1030.0
CMS2_k127_2011372_1 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 358.0
CMS2_k127_2011372_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000008052 123.0
CMS2_k127_2011372_3 TPR repeat - - - 0.000000000000000004303 92.0
CMS2_k127_2011372_4 - - - - 0.0000000000001108 72.0
CMS2_k127_2011372_5 Single cache domain 3 - - - 0.000000001044 63.0
CMS2_k127_2029784_0 PFAM Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 503.0
CMS2_k127_2029784_1 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 493.0
CMS2_k127_2029784_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000001558 145.0
CMS2_k127_2029784_3 Thioredoxin domain - - - 0.000000001964 59.0
CMS2_k127_204036_0 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 444.0
CMS2_k127_204036_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 436.0
CMS2_k127_204036_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 397.0
CMS2_k127_204036_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 404.0
CMS2_k127_204036_4 response regulator K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002897 267.0
CMS2_k127_204036_5 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000001039 172.0
CMS2_k127_204036_6 GatB Yqey domain protein K09117 - - 0.0000000000000000000000000000000000000001353 154.0
CMS2_k127_204036_7 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000004929 94.0
CMS2_k127_2069768_0 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001994 267.0
CMS2_k127_2069768_1 Domain of unknown function (DUF3842) - - - 0.00000000000000000000000000000000000000000000000005228 182.0
CMS2_k127_2069768_2 Protein of unknown function (DUF1284) K09706 - - 0.00000000000000000000000000007331 121.0
CMS2_k127_2069768_3 Predicted RNA-binding protein - - - 0.0000000000000000000002438 97.0
CMS2_k127_2069768_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000002 52.0
CMS2_k127_2074916_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 362.0
CMS2_k127_2074916_1 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 351.0
CMS2_k127_2074916_2 TPR repeat - - - 0.00000000000000000000000000000000000000000000000191 182.0
CMS2_k127_2074916_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000003983 127.0
CMS2_k127_2074916_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 0.00003453 46.0
CMS2_k127_2103133_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 4.88e-209 652.0
CMS2_k127_2103133_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 344.0
CMS2_k127_2103133_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003036 241.0
CMS2_k127_2103133_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000286 211.0
CMS2_k127_2103133_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000001101 198.0
CMS2_k127_2103133_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000001085 139.0
CMS2_k127_2103133_6 structural constituent of ribosome K02913 - - 0.000000000000000002946 84.0
CMS2_k127_2103133_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000003992 76.0
CMS2_k127_2103133_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000002151 71.0
CMS2_k127_2108100_0 Sugar (and other) transporter K03446 - - 4.753e-239 748.0
CMS2_k127_2108100_1 phosphorelay signal transduction system K02584,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 497.0
CMS2_k127_2108100_2 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 408.0
CMS2_k127_2108100_3 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 346.0
CMS2_k127_2108100_4 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000004672 206.0
CMS2_k127_2108453_0 PFAM Type II secretion system protein E K02454 - - 4.545e-203 643.0
CMS2_k127_2108453_1 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 306.0
CMS2_k127_2108453_2 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000007374 209.0
CMS2_k127_2108453_3 Prokaryotic N-terminal methylation motif K02457 - - 0.000000000000009192 83.0
CMS2_k127_2108453_4 Prokaryotic N-terminal methylation motif K02458 - - 0.00000002172 59.0
CMS2_k127_2154475_0 DNA topoisomerase II activity K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 2.218e-292 917.0
CMS2_k127_2154475_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 7.677e-196 617.0
CMS2_k127_2154475_10 nuclease activity K06218 - - 0.0000000000000001978 81.0
CMS2_k127_2154475_11 Tetratricopeptide repeat-like domain - - - 0.00000000000001206 83.0
CMS2_k127_2154475_13 PilZ domain - - - 0.000002095 56.0
CMS2_k127_2154475_14 COG1002 Type II restriction enzyme, methylase subunits - - - 0.000009598 49.0
CMS2_k127_2154475_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 546.0
CMS2_k127_2154475_3 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 522.0
CMS2_k127_2154475_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 464.0
CMS2_k127_2154475_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 400.0
CMS2_k127_2154475_6 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 390.0
CMS2_k127_2154475_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 332.0
CMS2_k127_2154475_8 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007831 271.0
CMS2_k127_2154475_9 competence protein - - - 0.0000000000000000000000000000000000000000855 160.0
CMS2_k127_2177084_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 605.0
CMS2_k127_2177084_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 320.0
CMS2_k127_2177084_2 Rubrerythrin - - - 0.0000000000000009608 83.0
CMS2_k127_2182354_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.564e-239 745.0
CMS2_k127_2182354_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.935e-210 667.0
CMS2_k127_2182354_2 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
CMS2_k127_2182354_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 288.0
CMS2_k127_2182354_5 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000000001139 87.0
CMS2_k127_2182354_6 Transcriptional regulator - - - 0.000001225 51.0
CMS2_k127_2210190_0 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 471.0
CMS2_k127_2210190_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 429.0
CMS2_k127_2210190_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 362.0
CMS2_k127_2210190_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 302.0
CMS2_k127_2210190_4 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000831 155.0
CMS2_k127_2210190_5 - - - - 0.00000000000000000000006336 105.0
CMS2_k127_2266128_0 GTP-binding protein TypA K06207 - - 4.117e-259 811.0
CMS2_k127_2266128_1 - - - - 0.0000000000000000000000000000007475 127.0
CMS2_k127_2270765_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 4.435e-207 647.0
CMS2_k127_2270765_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 286.0
CMS2_k127_2270765_2 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002145 258.0
CMS2_k127_2270765_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000001089 253.0
CMS2_k127_2367468_0 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 612.0
CMS2_k127_2367468_1 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009067 275.0
CMS2_k127_2367468_2 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000703 246.0
CMS2_k127_2367468_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000005148 216.0
CMS2_k127_2367468_4 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000118 176.0
CMS2_k127_2367468_5 Dissimilatory sulfite reductase D (DsrD) - - - 0.0000000000000000006906 89.0
CMS2_k127_2367468_6 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 0.00000000000000007487 80.0
CMS2_k127_2382299_0 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 450.0
CMS2_k127_2382299_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000001124 226.0
CMS2_k127_2382299_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000001596 109.0
CMS2_k127_2394923_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1176.0
CMS2_k127_2394923_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 3.86e-207 657.0
CMS2_k127_2394923_10 Cytochrome c7 and related cytochrome c - - - 0.00000000000000005189 87.0
CMS2_k127_2394923_11 calcium, potassium:sodium antiporter activity K07301 - - 0.000000000000001569 78.0
CMS2_k127_2394923_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 469.0
CMS2_k127_2394923_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 432.0
CMS2_k127_2394923_4 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 370.0
CMS2_k127_2394923_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000002092 225.0
CMS2_k127_2394923_6 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000004692 211.0
CMS2_k127_2394923_7 aminopeptidase N - - - 0.00000000000000000000000000000000000000000000000000008515 197.0
CMS2_k127_2394923_8 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000001665 98.0
CMS2_k127_2394923_9 hyperosmotic response K04065 - - 0.0000000000000000004237 91.0
CMS2_k127_2405617_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 451.0
CMS2_k127_2405617_1 TonB C terminal - - - 0.00000001683 67.0
CMS2_k127_2434074_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 1.632e-200 632.0
CMS2_k127_2434074_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 344.0
CMS2_k127_2434074_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 323.0
CMS2_k127_2434074_3 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000009018 230.0
CMS2_k127_2434074_5 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000002668 174.0
CMS2_k127_2434074_7 Methyltransferase type - - - 0.00000000000001583 73.0
CMS2_k127_2434074_8 protein secretion K03116,K03117 - - 0.00000000000002273 78.0
CMS2_k127_2434074_9 Cupin 2, conserved barrel domain protein - - - 0.000001582 49.0
CMS2_k127_246189_0 kinase activity K01006,K01007,K22424 - 2.7.3.13,2.7.9.1,2.7.9.2 6.206e-266 834.0
CMS2_k127_246189_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 548.0
CMS2_k127_246189_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 367.0
CMS2_k127_246189_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002977 281.0
CMS2_k127_246189_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000009195 168.0
CMS2_k127_2497100_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1111.0
CMS2_k127_2497100_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 601.0
CMS2_k127_2497100_10 Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000001408 181.0
CMS2_k127_2497100_11 - - - - 0.0000000000000000000000002136 111.0
CMS2_k127_2497100_12 - - - - 0.0000000000000159 77.0
CMS2_k127_2497100_13 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.0000003169 59.0
CMS2_k127_2497100_2 transposition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 453.0
CMS2_k127_2497100_3 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 413.0
CMS2_k127_2497100_4 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 395.0
CMS2_k127_2497100_5 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 319.0
CMS2_k127_2497100_6 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 287.0
CMS2_k127_2497100_7 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000001496 199.0
CMS2_k127_2497100_8 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000325 197.0
CMS2_k127_2497100_9 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000003312 184.0
CMS2_k127_2545933_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 592.0
CMS2_k127_2545933_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 309.0
CMS2_k127_2545933_2 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 304.0
CMS2_k127_2545933_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 285.0
CMS2_k127_2545933_4 DegT/DnrJ/EryC1/StrS aminotransferase family K14260 - 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000008845 240.0
CMS2_k127_2545933_5 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000133 226.0
CMS2_k127_255155_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 340.0
CMS2_k127_255155_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008997 280.0
CMS2_k127_255155_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006312 272.0
CMS2_k127_255155_3 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000536 134.0
CMS2_k127_2570345_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 308.0
CMS2_k127_2570345_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000004141 193.0
CMS2_k127_2570345_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000002079 156.0
CMS2_k127_2570345_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000004697 130.0
CMS2_k127_2573863_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 602.0
CMS2_k127_2573863_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 517.0
CMS2_k127_2573863_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 430.0
CMS2_k127_2573863_3 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 316.0
CMS2_k127_2573863_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 310.0
CMS2_k127_2573863_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001423 269.0
CMS2_k127_2573863_6 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000005532 270.0
CMS2_k127_2573863_7 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000002446 248.0
CMS2_k127_2573863_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000001187 192.0
CMS2_k127_2573863_9 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000002493 108.0
CMS2_k127_2613763_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 452.0
CMS2_k127_2613763_1 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 378.0
CMS2_k127_2613763_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003791 275.0
CMS2_k127_2613763_3 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009952 269.0
CMS2_k127_2613763_4 Lysin motif - - - 0.0000000000000003087 82.0
CMS2_k127_2616216_0 Belongs to the peptidase S16 family - - - 6.968e-229 734.0
CMS2_k127_2616216_1 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K11384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 449.0
CMS2_k127_2616216_10 S23 ribosomal protein - - - 0.00006949 51.0
CMS2_k127_2616216_2 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 424.0
CMS2_k127_2616216_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000004788 229.0
CMS2_k127_2616216_4 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000005799 195.0
CMS2_k127_2616216_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000867 185.0
CMS2_k127_2616216_6 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000001119 179.0
CMS2_k127_2616216_7 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000574 165.0
CMS2_k127_2616216_8 response regulator, receiver - - - 0.000000000000004897 79.0
CMS2_k127_2616216_9 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.000004248 56.0
CMS2_k127_2676410_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 412.0
CMS2_k127_2676410_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 401.0
CMS2_k127_2676410_2 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 368.0
CMS2_k127_2676410_3 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 347.0
CMS2_k127_2676410_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.000000000000000000000000000000000000000000000000000000001894 204.0
CMS2_k127_2676410_5 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000001663 203.0
CMS2_k127_2676410_6 DnaJ molecular chaperone homology domain - - - 0.000007799 58.0
CMS2_k127_2676410_7 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.00005502 55.0
CMS2_k127_2705127_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.634e-272 848.0
CMS2_k127_2705127_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000004053 193.0
CMS2_k127_2705127_2 low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000005297 158.0
CMS2_k127_2705127_3 Addiction module toxin, RelE StbE family K06218 - - 0.000000000000000000000002086 105.0
CMS2_k127_2705127_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000001846 91.0
CMS2_k127_2709317_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 403.0
CMS2_k127_2709317_1 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000006186 185.0
CMS2_k127_2709317_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000003299 180.0
CMS2_k127_2709317_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000001288 143.0
CMS2_k127_2709317_4 Outer membrane protein (OmpH-like) K06142 - - 0.00000000001048 72.0
CMS2_k127_2710084_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 562.0
CMS2_k127_2710084_1 PFAM Smr protein MutS2 - - - 0.000000000000000000000000000000003393 137.0
CMS2_k127_2717082_0 Aconitase C-terminal domain K01681 - 4.2.1.3 1.391e-300 933.0
CMS2_k127_2717082_1 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000009765 186.0
CMS2_k127_2717082_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000001736 158.0
CMS2_k127_2719451_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 1.374e-215 677.0
CMS2_k127_2719451_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 544.0
CMS2_k127_2719451_2 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 526.0
CMS2_k127_2719451_3 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 362.0
CMS2_k127_2719451_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 288.0
CMS2_k127_2719451_5 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.000000000000000000000000000000000000000009111 160.0
CMS2_k127_2719451_6 ThiS family K03636 - - 0.00000000000000000000000000000000001301 136.0
CMS2_k127_2719451_7 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000465 137.0
CMS2_k127_2719451_8 NIL - - - 0.00000000000000000000000000001964 118.0
CMS2_k127_2719451_9 PFAM Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.000000000009593 68.0
CMS2_k127_2757149_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 630.0
CMS2_k127_2757149_1 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 296.0
CMS2_k127_2757149_2 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001879 278.0
CMS2_k127_2757149_3 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000005081 143.0
CMS2_k127_2757149_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.0000000000000000000000000000000001528 144.0
CMS2_k127_2757149_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000003637 137.0
CMS2_k127_2757149_6 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000001965 128.0
CMS2_k127_2757149_7 - - - - 0.00000000000000000000000000531 113.0
CMS2_k127_275873_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 383.0
CMS2_k127_275873_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009372 268.0
CMS2_k127_275873_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000007173 144.0
CMS2_k127_2844618_0 glutamate synthase alpha subunit domain protein K00265 - 1.4.1.13,1.4.1.14 8.045e-236 748.0
CMS2_k127_2877038_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.885e-243 787.0
CMS2_k127_2877038_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 442.0
CMS2_k127_2877038_2 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000008122 236.0
CMS2_k127_2877038_3 PFAM periplasmic solute binding protein K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000004334 231.0
CMS2_k127_2877038_4 ABC-type Mn2 Zn2 transport system, permease component K09816,K09819,K19976 - - 0.00000000000000000000000000000000000000000000000000000000003075 214.0
CMS2_k127_2877038_5 Tetratricopeptide repeat - - - 0.0000000000000000003779 96.0
CMS2_k127_2877750_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.447e-271 851.0
CMS2_k127_2877750_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000001802 76.0
CMS2_k127_2878919_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 446.0
CMS2_k127_2878919_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000009389 208.0
CMS2_k127_2879085_0 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 466.0
CMS2_k127_2879085_1 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 359.0
CMS2_k127_2879085_2 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.0000000000000000000000000000000000000000000000005455 184.0
CMS2_k127_2924504_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1221.0
CMS2_k127_2924504_1 diguanylate cyclase - - - 0.000000000000000000003835 102.0
CMS2_k127_294125_0 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 562.0
CMS2_k127_294125_1 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 518.0
CMS2_k127_294125_3 Histidine kinase A domain protein - - - 0.0000000000000000000002903 104.0
CMS2_k127_2956379_0 Domain of unknown function (DUF4070) - - - 1.417e-211 668.0
CMS2_k127_2956379_1 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001232 261.0
CMS2_k127_2956379_2 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000001882 207.0
CMS2_k127_2956379_3 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000000005872 106.0
CMS2_k127_2956379_4 - - - - 0.0000000000000000002597 93.0
CMS2_k127_2956379_5 - - - - 0.000000000003121 71.0
CMS2_k127_2985246_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 421.0
CMS2_k127_2985246_1 - - - - 0.000000000000000001399 92.0
CMS2_k127_2985246_2 - - - - 0.0000314 48.0
CMS2_k127_3024905_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000001509 250.0
CMS2_k127_3024905_1 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000001646 110.0
CMS2_k127_3024905_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000008675 60.0
CMS2_k127_3025266_0 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 499.0
CMS2_k127_3025266_1 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 422.0
CMS2_k127_3025266_10 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000009893 159.0
CMS2_k127_3025266_11 Universal stress protein K06149 - - 0.000000000000000000000000000000000005705 141.0
CMS2_k127_3025266_12 proteolysis K03665 - - 0.000000000000000000003568 98.0
CMS2_k127_3025266_13 Translation initiation factor K03113 - - 0.0000000000000000003733 91.0
CMS2_k127_3025266_2 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 319.0
CMS2_k127_3025266_3 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 303.0
CMS2_k127_3025266_4 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 293.0
CMS2_k127_3025266_5 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000003298 253.0
CMS2_k127_3025266_6 PFAM FAD binding domain of DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000769 237.0
CMS2_k127_3025266_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000005874 190.0
CMS2_k127_3025266_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000001724 188.0
CMS2_k127_3025266_9 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000001455 182.0
CMS2_k127_3056909_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000118 271.0
CMS2_k127_3056909_1 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000001178 230.0
CMS2_k127_3056909_2 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000000000000000701 199.0
CMS2_k127_3056909_3 Uncharacterised protein family (UPF0158) - - - 0.0000000000000000000000004558 110.0
CMS2_k127_3056909_4 DNA restriction-modification system - GO:0000737,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006304,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009036,GO:0009056,GO:0009057,GO:0009307,GO:0009987,GO:0015666,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044355,GO:0046483,GO:0046700,GO:0050896,GO:0071704,GO:0090304,GO:0090305,GO:0099046,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000004592 72.0
CMS2_k127_3068924_0 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 467.0
CMS2_k127_3068924_1 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 409.0
CMS2_k127_3068924_2 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 398.0
CMS2_k127_3068924_3 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 366.0
CMS2_k127_3068924_4 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 299.0
CMS2_k127_3068924_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007752 269.0
CMS2_k127_3068924_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000131 257.0
CMS2_k127_3068924_7 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000006644 143.0
CMS2_k127_3105869_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 9.561e-268 848.0
CMS2_k127_3105869_1 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 600.0
CMS2_k127_3105869_10 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000009109 248.0
CMS2_k127_3105869_11 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000003822 242.0
CMS2_k127_3105869_12 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000000006986 203.0
CMS2_k127_3105869_13 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000001172 177.0
CMS2_k127_3105869_14 Thiamine-binding protein - - - 0.0000000000000000000000000000000004049 134.0
CMS2_k127_3105869_15 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000002595 127.0
CMS2_k127_3105869_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 534.0
CMS2_k127_3105869_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 514.0
CMS2_k127_3105869_4 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 486.0
CMS2_k127_3105869_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 422.0
CMS2_k127_3105869_6 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 404.0
CMS2_k127_3105869_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 385.0
CMS2_k127_3105869_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 344.0
CMS2_k127_3105869_9 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 317.0
CMS2_k127_3118977_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1087.0
CMS2_k127_3118977_1 Peptidase family M28 - - - 0.0 1085.0
CMS2_k127_3118977_2 Beta Propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 372.0
CMS2_k127_3118977_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000007733 199.0
CMS2_k127_3118977_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000004554 109.0
CMS2_k127_3132669_0 PFAM type II secretion system protein E K02283,K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 475.0
CMS2_k127_3132669_1 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009767 278.0
CMS2_k127_3132669_2 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004601 260.0
CMS2_k127_3132669_3 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000000000000000000000000000000004873 149.0
CMS2_k127_3133491_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 1.541e-314 987.0
CMS2_k127_3133491_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 462.0
CMS2_k127_3138123_0 Ecdysteroid kinase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 451.0
CMS2_k127_3138123_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000171 304.0
CMS2_k127_3138123_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000001372 229.0
CMS2_k127_3138123_3 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.000000000000000000000000000000000000000000003762 166.0
CMS2_k127_3138123_4 peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000704 164.0
CMS2_k127_3138123_5 CGGC - - - 0.0000000000000000000000000000000000000003903 152.0
CMS2_k127_3138123_6 Protein of unknown function DUF134 - - - 0.0000000000000000000000000406 109.0
CMS2_k127_3138123_7 hydrogenase maturation protease K03605 - - 0.000000000000000000000001668 108.0
CMS2_k127_3175820_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1112.0
CMS2_k127_3175820_1 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 375.0
CMS2_k127_3175820_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001168 260.0
CMS2_k127_3175820_4 - K07803 - - 0.000119 49.0
CMS2_k127_3178841_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.332e-255 811.0
CMS2_k127_3178841_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 4.786e-203 637.0
CMS2_k127_3178841_2 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 331.0
CMS2_k127_3178841_3 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004453 275.0
CMS2_k127_3178841_4 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000498 246.0
CMS2_k127_3178841_5 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000008034 162.0
CMS2_k127_3178841_6 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000003781 133.0
CMS2_k127_3178841_7 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000000000000001057 97.0
CMS2_k127_3178841_8 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000000001132 96.0
CMS2_k127_318946_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1100.0
CMS2_k127_318946_1 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 331.0
CMS2_k127_318946_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 314.0
CMS2_k127_318946_3 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000002364 273.0
CMS2_k127_318946_4 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000000009599 229.0
CMS2_k127_318946_5 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000799 127.0
CMS2_k127_318946_6 SpoVT / AbrB like domain K07172 - - 0.0000000000000009228 79.0
CMS2_k127_318946_7 Two component regulator propeller - - - 0.000000000000008592 82.0
CMS2_k127_3231603_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1122.0
CMS2_k127_3231603_1 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 461.0
CMS2_k127_3231603_10 small metal-binding protein - - - 0.00000002203 57.0
CMS2_k127_3231603_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 370.0
CMS2_k127_3231603_3 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 313.0
CMS2_k127_3231603_4 NosL - - - 0.0000000000000000000000000000000000000000000000000000004539 198.0
CMS2_k127_3231603_5 NosL - - - 0.0000000000000000000000000000000000000000000000004057 180.0
CMS2_k127_3231603_6 Thioredoxin-like - - - 0.000000000000000000000000000001022 127.0
CMS2_k127_3231603_7 - - - - 0.000000000000000000002507 98.0
CMS2_k127_3231603_8 Transcriptional regulator, DeoR family K21601 - - 0.000000000000000002988 90.0
CMS2_k127_3231603_9 lipoprotein involved in nitrous oxide reduction K21601 - - 0.000000000287 67.0
CMS2_k127_3242211_0 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 383.0
CMS2_k127_3242211_1 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 308.0
CMS2_k127_3242211_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 293.0
CMS2_k127_3242211_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
CMS2_k127_3242211_4 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.000000000000000000000000000000000000000005755 155.0
CMS2_k127_3242211_5 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000004447 148.0
CMS2_k127_3242211_6 Putative regulatory protein - - - 0.000000000000000000000008439 103.0
CMS2_k127_3242211_7 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000001249 100.0
CMS2_k127_3242211_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000001847 85.0
CMS2_k127_3246300_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1186.0
CMS2_k127_3246300_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 1.189e-256 812.0
CMS2_k127_3246300_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 592.0
CMS2_k127_3246300_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 458.0
CMS2_k127_3246300_4 PFAM PfkB K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 394.0
CMS2_k127_3246300_5 Transposase, Mutator family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000301 260.0
CMS2_k127_3246300_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000002844 224.0
CMS2_k127_3246300_7 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000009665 207.0
CMS2_k127_3246300_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000001755 104.0
CMS2_k127_3252645_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.411e-217 680.0
CMS2_k127_3252645_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 441.0
CMS2_k127_3252645_10 Belongs to the UPF0102 family K07460 - - 0.000000000000000005593 88.0
CMS2_k127_3252645_11 Ribosomal protein L36 K02919 - - 0.00000000000002172 72.0
CMS2_k127_3252645_12 General secretory system II protein E domain protein K02652 - - 0.000006093 48.0
CMS2_k127_3252645_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 360.0
CMS2_k127_3252645_3 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 314.0
CMS2_k127_3252645_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001041 273.0
CMS2_k127_3252645_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000003366 213.0
CMS2_k127_3252645_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000228 184.0
CMS2_k127_3252645_7 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000001397 168.0
CMS2_k127_3252645_8 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.000000000000000000000000000000000000000007654 158.0
CMS2_k127_3252645_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000000000004751 131.0
CMS2_k127_3278741_0 Belongs to the glycosyl hydrolase 57 family - - - 6.484e-298 923.0
CMS2_k127_3278741_1 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase K01236 - 3.2.1.141 9.053e-250 785.0
CMS2_k127_3288931_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 492.0
CMS2_k127_3288931_1 Protein of unknown function, DUF481 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 342.0
CMS2_k127_3288931_2 mechanosensitive ion channel activity - - - 0.00000000000000000000000000000000000000000000000000000000000000009828 224.0
CMS2_k127_3288931_3 mechanosensitive ion channel activity - - - 0.0000000000000000000000059 104.0
CMS2_k127_3297412_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.525e-218 694.0
CMS2_k127_3297412_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 524.0
CMS2_k127_3297412_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 439.0
CMS2_k127_3297412_3 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 378.0
CMS2_k127_3297412_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004083 278.0
CMS2_k127_3297412_5 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000002127 220.0
CMS2_k127_3301566_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 302.0
CMS2_k127_3301566_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000001999 188.0
CMS2_k127_3304972_0 Transport of potassium into the cell K03549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 593.0
CMS2_k127_3304972_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000003194 251.0
CMS2_k127_3304972_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000464 194.0
CMS2_k127_3328152_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 417.0
CMS2_k127_3328152_1 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 336.0
CMS2_k127_3328152_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001252 272.0
CMS2_k127_3328152_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000008729 236.0
CMS2_k127_3328152_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000006242 147.0
CMS2_k127_3330956_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.091e-282 878.0
CMS2_k127_3330956_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.000000000000000000000000000000000489 132.0
CMS2_k127_334029_0 Heat shock 70 kDa protein K04043 - - 0.0 1007.0
CMS2_k127_334029_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 476.0
CMS2_k127_334029_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000261 167.0
CMS2_k127_334029_11 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000003233 116.0
CMS2_k127_334029_12 Protein of unknown function (DUF507) - - - 0.00000000000000000000000001897 111.0
CMS2_k127_334029_13 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000002467 111.0
CMS2_k127_334029_14 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000003989 106.0
CMS2_k127_334029_15 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000004431 99.0
CMS2_k127_334029_16 diguanylate cyclase - - - 0.0000000000000000000001398 100.0
CMS2_k127_334029_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 382.0
CMS2_k127_334029_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 347.0
CMS2_k127_334029_4 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007822 256.0
CMS2_k127_334029_5 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000001411 220.0
CMS2_k127_334029_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000003667 214.0
CMS2_k127_334029_7 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000001124 177.0
CMS2_k127_334029_8 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000001478 169.0
CMS2_k127_334029_9 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases gamma subunit K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000002053 170.0
CMS2_k127_3345794_0 PIN domain - - - 0.0000000000000000000000000000000000000000000001837 171.0
CMS2_k127_3345794_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000517 175.0
CMS2_k127_3384641_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 616.0
CMS2_k127_3384641_1 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 549.0
CMS2_k127_3384641_2 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 365.0
CMS2_k127_3384641_3 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 316.0
CMS2_k127_3384641_4 PFAM response regulator receiver K07775 - - 0.0001063 47.0
CMS2_k127_338813_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 596.0
CMS2_k127_338813_1 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 494.0
CMS2_k127_338813_2 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 319.0
CMS2_k127_338813_3 diguanylate cyclase activity - - - 0.000000000000000003006 91.0
CMS2_k127_3444343_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 588.0
CMS2_k127_3444343_1 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 375.0
CMS2_k127_3444343_2 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000002944 211.0
CMS2_k127_3482896_1 PFAM Protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 454.0
CMS2_k127_3482896_10 CHASE2 K01768 - 4.6.1.1 0.0000005519 57.0
CMS2_k127_3482896_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
CMS2_k127_3482896_3 calcium, potassium:sodium antiporter activity K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 373.0
CMS2_k127_3482896_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 305.0
CMS2_k127_3482896_5 CO dehydrogenase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 295.0
CMS2_k127_3482896_6 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000006559 244.0
CMS2_k127_3482896_7 AMP binding - - - 0.0000000000000000000000000000000000000000000000000001266 196.0
CMS2_k127_3482896_8 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000001077 155.0
CMS2_k127_3482896_9 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.000000000000000000000000000000000003714 143.0
CMS2_k127_3492933_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 480.0
CMS2_k127_3492933_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 459.0
CMS2_k127_3492933_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 297.0
CMS2_k127_3492933_3 Peptidase S24-like K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000007491 219.0
CMS2_k127_3492933_4 Transposase - - - 0.00000000000000000000000000000000000000000000000000000001496 205.0
CMS2_k127_3528318_0 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 401.0
CMS2_k127_3528318_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 295.0
CMS2_k127_3528318_2 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001015 265.0
CMS2_k127_3528318_3 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.0000000000000000000000000000000002353 135.0
CMS2_k127_3528318_4 TonB C terminal K03832 - - 0.0000000000000000000000000002898 125.0
CMS2_k127_3537098_0 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 490.0
CMS2_k127_3537098_1 Protein of unknown function (DUF2845) - - - 0.00000000000000003823 86.0
CMS2_k127_3540660_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.724e-246 770.0
CMS2_k127_3540660_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 494.0
CMS2_k127_3540660_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 414.0
CMS2_k127_3540660_3 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008569 384.0
CMS2_k127_3540660_4 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003613 255.0
CMS2_k127_3540660_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000004317 244.0
CMS2_k127_3540660_6 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000006947 131.0
CMS2_k127_3540660_7 OsmC-like protein - - - 0.0000000000000000000000001832 107.0
CMS2_k127_3546592_0 cell redox homeostasis - - - 3.826e-205 648.0
CMS2_k127_3546592_1 - K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 437.0
CMS2_k127_3546592_10 - - - - 0.000000000000000000000009456 109.0
CMS2_k127_3546592_11 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000002261 74.0
CMS2_k127_3546592_12 3D domain protein - - - 0.0000000001746 66.0
CMS2_k127_3546592_13 helix_turn_helix, Lux Regulon - - - 0.00000007931 62.0
CMS2_k127_3546592_14 PFAM Uncharacterised protein family UPF0150 - - - 0.0002478 46.0
CMS2_k127_3546592_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 392.0
CMS2_k127_3546592_3 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 284.0
CMS2_k127_3546592_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006175 262.0
CMS2_k127_3546592_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000001454 166.0
CMS2_k127_3546592_6 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000000000004662 164.0
CMS2_k127_3546592_7 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000005414 157.0
CMS2_k127_3546592_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000002157 139.0
CMS2_k127_3546592_9 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000002281 130.0
CMS2_k127_3546853_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 465.0
CMS2_k127_3546853_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 354.0
CMS2_k127_3546853_2 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 347.0
CMS2_k127_3546853_3 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009183 284.0
CMS2_k127_3546853_4 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000000008459 160.0
CMS2_k127_356199_0 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 347.0
CMS2_k127_356199_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007686 270.0
CMS2_k127_356199_2 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000006194 77.0
CMS2_k127_3564296_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 419.0
CMS2_k127_3564296_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 404.0
CMS2_k127_3564296_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 405.0
CMS2_k127_3564296_3 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 343.0
CMS2_k127_3564296_4 Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 324.0
CMS2_k127_3564296_5 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004429 243.0
CMS2_k127_3564296_6 O-acyltransferase activity K08280 - - 0.000000000000000000000000000000000000000000000000000000001665 204.0
CMS2_k127_3608017_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 551.0
CMS2_k127_3608017_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 488.0
CMS2_k127_3608017_2 Putative Fe-S cluster K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 313.0
CMS2_k127_3608017_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000366 273.0
CMS2_k127_3608017_4 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002437 245.0
CMS2_k127_3608017_5 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000005685 179.0
CMS2_k127_3608017_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000008887 158.0
CMS2_k127_3608017_7 Rhodanese Homology Domain - - - 0.0000000000000000000000000242 109.0
CMS2_k127_3608017_8 - - - - 0.00000000001838 64.0
CMS2_k127_3608017_9 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.0002036 47.0
CMS2_k127_3634145_0 GXGXG motif - - - 0.0 1037.0
CMS2_k127_3634145_1 GAF domain K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 544.0
CMS2_k127_3634145_2 Glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 302.0
CMS2_k127_3645151_0 phosphorelay signal transduction system K02584,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 501.0
CMS2_k127_3645151_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 426.0
CMS2_k127_3645151_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001719 264.0
CMS2_k127_3645151_3 helix_turn_helix gluconate operon transcriptional repressor K03710 - - 0.0000000000000000000000000000001411 133.0
CMS2_k127_3645151_4 PFAM UspA domain protein - - - 0.00000000000000001164 89.0
CMS2_k127_3645151_5 membrane transporter protein K07090 - - 0.00000000000000004234 82.0
CMS2_k127_3665903_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 535.0
CMS2_k127_3665903_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 394.0
CMS2_k127_3665903_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001019 285.0
CMS2_k127_3665903_3 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000005487 235.0
CMS2_k127_3677648_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0 1255.0
CMS2_k127_3677648_1 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 488.0
CMS2_k127_3677648_2 Glycosyl transferase family 41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 445.0
CMS2_k127_3677648_3 phosphonoacetaldehyde hydrolase activity K01087,K01194,K01838,K05342 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.64,3.1.3.12,3.2.1.28,5.4.2.6 0.0000000000000000000000000000000004805 133.0
CMS2_k127_3678648_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 613.0
CMS2_k127_3678648_1 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 358.0
CMS2_k127_3678648_2 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000002717 230.0
CMS2_k127_3680155_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 545.0
CMS2_k127_3680155_1 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 391.0
CMS2_k127_3680155_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 365.0
CMS2_k127_3680155_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 301.0
CMS2_k127_3680155_4 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000004522 225.0
CMS2_k127_3680155_5 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000003733 213.0
CMS2_k127_3680155_6 Response regulator, receiver K11443 - - 0.00000000000000000000000000000000000000000000555 168.0
CMS2_k127_369172_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 461.0
CMS2_k127_369172_1 PFAM glycosyl transferase, family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 353.0
CMS2_k127_369172_2 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001528 272.0
CMS2_k127_369172_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.000000000000000000000000000000000000000000000000007533 184.0
CMS2_k127_3697482_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 548.0
CMS2_k127_3697482_1 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 308.0
CMS2_k127_3697482_2 Domain of unknown function (DUF4870) K09940 - - 0.00000000000000000000000000005473 120.0
CMS2_k127_3697482_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000003723 91.0
CMS2_k127_3737124_0 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 2.986e-201 633.0
CMS2_k127_3737124_1 sister chromatid segregation - - - 1.308e-197 627.0
CMS2_k127_3737124_10 Belongs to the peptidase S8 family - - - 0.0000000000000000001883 96.0
CMS2_k127_3737124_11 PFAM Radical SAM domain protein - - - 0.0000000000000002914 80.0
CMS2_k127_3737124_2 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001116 247.0
CMS2_k127_3737124_3 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003194 245.0
CMS2_k127_3737124_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000004877 203.0
CMS2_k127_3737124_5 - - - - 0.00000000000000000000000000000000000000000000000000646 183.0
CMS2_k127_3737124_6 radical SAM K06871 - - 0.0000000000000000000000000000000000007733 151.0
CMS2_k127_3737124_7 part of a sulfur-relay system - - - 0.0000000000000000000000000000008052 123.0
CMS2_k127_3737124_8 - - - - 0.0000000000000000000000000001654 132.0
CMS2_k127_3737124_9 electron transfer activity K05337,K17247 - - 0.000000000000000000002139 94.0
CMS2_k127_3746729_0 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 315.0
CMS2_k127_3746729_1 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000002641 249.0
CMS2_k127_3746729_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000002892 238.0
CMS2_k127_375692_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 9.46e-277 860.0
CMS2_k127_375692_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 363.0
CMS2_k127_375692_2 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000002021 212.0
CMS2_k127_375692_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000003611 198.0
CMS2_k127_375692_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000001607 187.0
CMS2_k127_375692_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000006297 153.0
CMS2_k127_375692_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000227 89.0
CMS2_k127_3793425_0 S23 ribosomal protein - - - 0.000000000000000000000000000000007978 130.0
CMS2_k127_3793425_1 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000007102 125.0
CMS2_k127_3793425_2 Prokaryotic N-terminal methylation motif - - - 0.0006183 48.0
CMS2_k127_3793425_3 - - - - 0.0006907 48.0
CMS2_k127_3825058_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.566e-197 636.0
CMS2_k127_3825058_1 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 478.0
CMS2_k127_3825058_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000001028 217.0
CMS2_k127_3825058_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000001707 199.0
CMS2_k127_3825058_4 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000001074 190.0
CMS2_k127_3825058_5 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000001141 144.0
CMS2_k127_3893489_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 534.0
CMS2_k127_3893489_1 AI-2E family transporter - - - 0.000000000000000000000000000002911 126.0
CMS2_k127_3893489_2 NADPH-dependent FMN reductase - - - 0.000000000000000000000000289 117.0
CMS2_k127_3893489_3 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000007679 76.0
CMS2_k127_3893489_4 Phospholipid methyltransferase - - - 0.00000000447 64.0
CMS2_k127_3908090_0 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004217 263.0
CMS2_k127_3908090_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000001576 159.0
CMS2_k127_3912051_0 protein secretion K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008656 287.0
CMS2_k127_3912051_1 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.0000000000000002405 91.0
CMS2_k127_3919209_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.152e-204 646.0
CMS2_k127_3919209_1 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005242 254.0
CMS2_k127_3919569_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 8.112e-228 725.0
CMS2_k127_3919569_1 HMGL-like K01666 - 4.1.3.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 354.0
CMS2_k127_3919569_2 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 309.0
CMS2_k127_3919569_3 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000834 171.0
CMS2_k127_3919569_5 - - - - 0.00000000000001423 75.0
CMS2_k127_3928231_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 354.0
CMS2_k127_3928231_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 352.0
CMS2_k127_3928231_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000501 276.0
CMS2_k127_3928231_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002194 267.0
CMS2_k127_3928231_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000001486 222.0
CMS2_k127_3928231_5 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000007779 157.0
CMS2_k127_3989066_0 Homeodomain-like domain - - - 0.0000000000000000000000000000000000000000000000000005179 198.0
CMS2_k127_3989066_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.0000000000001964 74.0
CMS2_k127_3989066_2 Psort location CytoplasmicMembrane, score 10.00 K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000006541 64.0
CMS2_k127_3989066_3 Protein of unknown function (DUF1015) - - - 0.000000006154 58.0
CMS2_k127_4001334_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.213e-289 908.0
CMS2_k127_4001334_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.703e-226 729.0
CMS2_k127_4001334_10 SPTR S-layer domain protein domain protein - - - 0.00001752 57.0
CMS2_k127_4001334_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 597.0
CMS2_k127_4001334_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 334.0
CMS2_k127_4001334_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000001748 258.0
CMS2_k127_4001334_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000005584 145.0
CMS2_k127_4001334_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000007321 98.0
CMS2_k127_4001334_7 PFAM phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000009939 84.0
CMS2_k127_4001334_8 Domain of unknown function (DUF4912) K09942 - - 0.000000000000005313 87.0
CMS2_k127_4001334_9 Protein of unknown function (DUF721) - - - 0.00000003386 61.0
CMS2_k127_4009909_0 teichoic acid transport K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 297.0
CMS2_k127_4009909_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000002834 155.0
CMS2_k127_4026704_0 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 6.534e-211 666.0
CMS2_k127_4026704_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008315 472.0
CMS2_k127_4026704_10 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000001158 98.0
CMS2_k127_4026704_11 Tetratricopeptide repeat - - - 0.000000000000000000003463 106.0
CMS2_k127_4026704_12 Universal stress protein - - - 0.000000000000000002677 95.0
CMS2_k127_4026704_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 394.0
CMS2_k127_4026704_3 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 301.0
CMS2_k127_4026704_4 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005235 256.0
CMS2_k127_4026704_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000007301 248.0
CMS2_k127_4026704_6 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000001067 224.0
CMS2_k127_4026704_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000001955 189.0
CMS2_k127_4026704_8 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000001669 171.0
CMS2_k127_4026704_9 Roadblock/LC7 domain - - - 0.0000000000000000000004616 99.0
CMS2_k127_4054011_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 7.069e-271 843.0
CMS2_k127_4054011_1 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 464.0
CMS2_k127_4054011_10 lipoprotein involved in nitrous oxide reduction K21601 - - 0.000000000002767 74.0
CMS2_k127_4054011_11 Cytochrome c5530 family protein - - - 0.0003345 45.0
CMS2_k127_4054011_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 377.0
CMS2_k127_4054011_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 370.0
CMS2_k127_4054011_4 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 314.0
CMS2_k127_4054011_5 NosL - - - 0.000000000000000000000000000000000000000000000000000009009 196.0
CMS2_k127_4054011_6 NosL - - - 0.00000000000000000000000000000000000000000000000000002125 192.0
CMS2_k127_4054011_7 Thioredoxin-like - - - 0.0000000000000000000000000000000001739 139.0
CMS2_k127_4054011_8 - - - - 0.00000000000000000002221 94.0
CMS2_k127_4054011_9 Transcriptional regulator, DeoR family K21601 - - 0.0000000000000001306 89.0
CMS2_k127_405854_0 PUA-like domain K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 417.0
CMS2_k127_405854_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 364.0
CMS2_k127_4075389_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.937e-242 757.0
CMS2_k127_4075389_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.466e-234 739.0
CMS2_k127_4075389_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 608.0
CMS2_k127_4075389_3 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 364.0
CMS2_k127_4075389_4 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 335.0
CMS2_k127_4075389_5 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001114 276.0
CMS2_k127_4075389_6 - - - - 0.00000000000000000000003184 108.0
CMS2_k127_4101755_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 374.0
CMS2_k127_4101755_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000001055 199.0
CMS2_k127_4101755_2 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000008961 130.0
CMS2_k127_4101755_3 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000004385 73.0
CMS2_k127_4101755_4 NusG domain II - - - 0.00000000000306 72.0
CMS2_k127_4111361_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 9.048e-225 705.0
CMS2_k127_4111361_1 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000001882 134.0
CMS2_k127_4137824_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 456.0
CMS2_k127_4137824_1 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 454.0
CMS2_k127_4137824_2 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 443.0
CMS2_k127_4137824_3 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 418.0
CMS2_k127_4167007_0 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 531.0
CMS2_k127_4167007_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 417.0
CMS2_k127_4167007_2 iron-sulfur transferase activity K07126,K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 349.0
CMS2_k127_4167007_3 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000001568 194.0
CMS2_k127_4178927_0 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 399.0
CMS2_k127_4178927_1 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000004927 219.0
CMS2_k127_4178927_2 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000001019 159.0
CMS2_k127_4178927_3 PFAM Peptidase family M28 - - - 0.000000000000005079 76.0
CMS2_k127_4184006_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.323e-201 639.0
CMS2_k127_4184006_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000001417 172.0
CMS2_k127_4184006_2 PFAM dihydropteroate synthase, DHPS K00548 - 2.1.1.13 0.0000000000000000000000321 109.0
CMS2_k127_4189601_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.22e-247 773.0
CMS2_k127_4189601_1 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 381.0
CMS2_k127_4189601_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 292.0
CMS2_k127_4189601_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000004701 232.0
CMS2_k127_4189601_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000002546 231.0
CMS2_k127_4189601_5 Dihydroorotate dehydrogenase electron transfer subunit K02823 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0042602,GO:0052875,GO:0055114 - 0.00000000000000000000000000000000000000000000000000019 194.0
CMS2_k127_4189601_6 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000007127 185.0
CMS2_k127_4189601_7 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000001065 183.0
CMS2_k127_4189601_8 gas vesicle protein - - - 0.00000000000000000000003122 103.0
CMS2_k127_4189601_9 part of a sulfur-relay system - - - 0.0000000004722 64.0
CMS2_k127_4208213_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 377.0
CMS2_k127_4245982_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 563.0
CMS2_k127_4245982_1 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 374.0
CMS2_k127_4245982_2 PFAM CoA-binding domain protein K01905 - 6.2.1.13 0.0000000000000000000000000000000004805 133.0
CMS2_k127_4245982_3 Putative regulatory protein - - - 0.000000005287 59.0
CMS2_k127_4294946_0 Phosphoglycerate kinase K00927 - 2.7.2.3 6.317e-199 626.0
CMS2_k127_4294946_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 494.0
CMS2_k127_4294946_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000000000005377 231.0
CMS2_k127_4299593_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1702.0
CMS2_k127_4299593_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 523.0
CMS2_k127_4300846_0 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 481.0
CMS2_k127_4300846_1 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 334.0
CMS2_k127_4300846_2 Rhomboid family - - - 0.0000000000000000000000000000000000006548 143.0
CMS2_k127_4302976_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 3.746e-229 733.0
CMS2_k127_4302976_1 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 586.0
CMS2_k127_4302976_10 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000006377 127.0
CMS2_k127_4302976_11 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000001315 121.0
CMS2_k127_4302976_12 Drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000004511 109.0
CMS2_k127_4302976_13 - - - - 0.0000000000001124 77.0
CMS2_k127_4302976_2 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 556.0
CMS2_k127_4302976_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 544.0
CMS2_k127_4302976_4 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 457.0
CMS2_k127_4302976_5 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 365.0
CMS2_k127_4302976_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 351.0
CMS2_k127_4302976_7 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002204 265.0
CMS2_k127_4302976_8 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000052 237.0
CMS2_k127_4302976_9 CopG antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000000000000002902 127.0
CMS2_k127_4314882_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 326.0
CMS2_k127_4314882_1 elongation factor Tu domain 2 protein K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000119 222.0
CMS2_k127_4314882_2 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00005627 51.0
CMS2_k127_4331848_0 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000007475 200.0
CMS2_k127_4331848_1 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000002248 199.0
CMS2_k127_4331848_2 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000000000000000029 138.0
CMS2_k127_4331848_3 COG1522 Transcriptional regulators - - - 0.00000000000000927 76.0
CMS2_k127_4331848_4 Belongs to the 'phage' integrase family - - - 0.0000000000006405 74.0
CMS2_k127_4380449_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 330.0
CMS2_k127_4380449_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002927 301.0
CMS2_k127_4380449_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004412 271.0
CMS2_k127_4380449_3 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000003091 244.0
CMS2_k127_4380449_4 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000002367 175.0
CMS2_k127_4380449_5 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K00558 - 2.1.1.37 0.000000000000000000169 91.0
CMS2_k127_438569_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.411e-231 722.0
CMS2_k127_438569_1 Elongation factor SelB, winged helix K03833 - - 9.799e-217 689.0
CMS2_k127_438569_2 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 494.0
CMS2_k127_438569_3 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 429.0
CMS2_k127_438569_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 249.0
CMS2_k127_438569_5 Fic/DOC family N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000001434 222.0
CMS2_k127_438569_6 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000004222 190.0
CMS2_k127_438569_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000002986 143.0
CMS2_k127_438569_8 Fic/DOC family - - - 0.000000000000000000000000000000009863 131.0
CMS2_k127_438569_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000001012 113.0
CMS2_k127_4397867_0 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000003226 191.0
CMS2_k127_4397867_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000007633 147.0
CMS2_k127_4397867_2 response regulator - - - 0.0000000000000000000000000000000000004649 143.0
CMS2_k127_4397867_3 Histidine kinase - - - 0.0000000000000000000000000000002056 130.0
CMS2_k127_4397867_4 phosphorelay signal transduction system K07315 - 3.1.3.3 0.00000000000000000000000000004807 120.0
CMS2_k127_4407827_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 534.0
CMS2_k127_4411765_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.512e-206 651.0
CMS2_k127_4411765_1 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 598.0
CMS2_k127_4411765_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 487.0
CMS2_k127_4411765_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 367.0
CMS2_k127_4411765_4 SMART HNH nuclease K07451 - - 0.000000000000000000000000000000000000000008063 155.0
CMS2_k127_4411765_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000005814 142.0
CMS2_k127_4411765_6 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000002925 128.0
CMS2_k127_4439280_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.371e-204 642.0
CMS2_k127_4439280_1 TIGRFAM molybdenum cofactor synthesis domain - - - 0.00000000000000000000000000000000000000000000000000000000003591 209.0
CMS2_k127_4439280_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000008208 205.0
CMS2_k127_4439280_3 PFAM MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000003715 200.0
CMS2_k127_4439280_4 PBP superfamily domain K02040 - - 0.000000002845 59.0
CMS2_k127_446718_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 1.833e-321 998.0
CMS2_k127_446718_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 517.0
CMS2_k127_446718_2 metal-dependent enzyme K09153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 323.0
CMS2_k127_446718_3 Binds the 23S rRNA K02909 - - 0.000000000000000000000000001505 113.0
CMS2_k127_4486848_0 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 441.0
CMS2_k127_4486848_1 transcriptional regulator - - - 0.00007303 52.0
CMS2_k127_4507848_0 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 411.0
CMS2_k127_4507848_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001585 253.0
CMS2_k127_4507848_2 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000006336 223.0
CMS2_k127_4507848_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000007839 147.0
CMS2_k127_4507848_4 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000000000000001683 139.0
CMS2_k127_4507848_5 OstA-like protein K09774 - - 0.0000000000000000000000000000006644 128.0
CMS2_k127_4507848_6 PFAM YcfA family protein - - - 0.0000000000000000000000000003061 114.0
CMS2_k127_4507848_7 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.0000000000000000000008254 95.0
CMS2_k127_4507848_8 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000006745 57.0
CMS2_k127_4581427_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 1.029e-197 674.0
CMS2_k127_4581427_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 446.0
CMS2_k127_4581427_10 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000000000712 147.0
CMS2_k127_4581427_12 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000001797 67.0
CMS2_k127_4581427_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 384.0
CMS2_k127_4581427_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000523 312.0
CMS2_k127_4581427_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 298.0
CMS2_k127_4581427_5 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 287.0
CMS2_k127_4581427_6 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004647 287.0
CMS2_k127_4581427_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000002755 238.0
CMS2_k127_4581427_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000498 218.0
CMS2_k127_4581427_9 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000001227 179.0
CMS2_k127_4587196_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 3.174e-303 944.0
CMS2_k127_4587196_1 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 469.0
CMS2_k127_4597972_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1260.0
CMS2_k127_4597972_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000001722 70.0
CMS2_k127_4601654_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 511.0
CMS2_k127_4601654_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 512.0
CMS2_k127_4601654_10 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001198 65.0
CMS2_k127_4601654_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000007375 242.0
CMS2_k127_4601654_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000002289 237.0
CMS2_k127_4601654_4 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000002502 242.0
CMS2_k127_4601654_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000003818 198.0
CMS2_k127_4601654_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000002333 112.0
CMS2_k127_4601654_7 - - - - 0.000000000000000000000000192 106.0
CMS2_k127_4601654_8 Belongs to the 'phage' integrase family - - - 0.00000000000000000000003309 100.0
CMS2_k127_4601654_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000001723 84.0
CMS2_k127_4610647_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 451.0
CMS2_k127_4610647_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 337.0
CMS2_k127_4610647_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009444 282.0
CMS2_k127_4610647_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001111 268.0
CMS2_k127_4610647_4 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000001331 241.0
CMS2_k127_4610647_5 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000000000000000244 158.0
CMS2_k127_4610647_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000002499 166.0
CMS2_k127_4612735_0 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000478 284.0
CMS2_k127_4612735_1 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000003761 201.0
CMS2_k127_4612735_2 transposition K07497 - - 0.000000000000000005813 96.0
CMS2_k127_4612735_3 PFAM Transposase IS3 IS911 K07497 - - 0.000000001953 63.0
CMS2_k127_4653316_0 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000003566 227.0
CMS2_k127_4653316_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000001705 225.0
CMS2_k127_4653316_2 Pfam Response regulator receiver - - - 0.000000000000000000000000003691 124.0
CMS2_k127_466197_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 3.041e-291 904.0
CMS2_k127_466197_1 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 417.0
CMS2_k127_466197_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000004 257.0
CMS2_k127_466197_3 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000001444 224.0
CMS2_k127_466197_4 nucleoside-diphosphate sugar epimerase K07071 - - 0.00004337 46.0
CMS2_k127_4671321_0 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 521.0
CMS2_k127_4671321_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 329.0
CMS2_k127_4671321_2 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001172 292.0
CMS2_k127_4671321_3 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000000000000000125 186.0
CMS2_k127_4671321_4 Domain of unknown function (DUF4412) - - - 0.00000000000000000000000000000000000000000000003348 177.0
CMS2_k127_4671321_5 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000000000002002 117.0
CMS2_k127_4671321_6 protein secretion K09800 - - 0.000000001504 67.0
CMS2_k127_4682093_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1101.0
CMS2_k127_4682093_1 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000000000000332 192.0
CMS2_k127_4682093_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000001985 126.0
CMS2_k127_4682093_3 Thioredoxin-like - - - 0.0000000000000000000000000000005907 128.0
CMS2_k127_4682093_4 23S rRNA-intervening sequence protein - - - 0.00000005841 56.0
CMS2_k127_4683056_0 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 391.0
CMS2_k127_4683056_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 319.0
CMS2_k127_4683056_2 wide pore channel activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 297.0
CMS2_k127_4683056_3 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002497 255.0
CMS2_k127_4683056_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000001798 209.0
CMS2_k127_4683056_5 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000002673 192.0
CMS2_k127_4683056_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000003933 164.0
CMS2_k127_4683056_7 Belongs to the RNA methyltransferase TrmD family K00554,K01770 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 0.00000000000000000000000000000008123 126.0
CMS2_k127_4691275_0 - - - - 0.000000000000000000000000000000000000000000002179 170.0
CMS2_k127_4691275_1 photosynthesis - - - 0.00000000000000000000000000000000000002744 150.0
CMS2_k127_4691275_2 - - - - 0.00000000000000000000000000000001083 132.0
CMS2_k127_4691275_3 MlaD protein K02067 - - 0.00000000000000000000004649 103.0
CMS2_k127_4702508_0 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000008498 169.0
CMS2_k127_4702508_1 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000218 176.0
CMS2_k127_4702508_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000005073 124.0
CMS2_k127_4702508_3 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000000005858 113.0
CMS2_k127_4751041_0 FAD binding domain K00278 - 1.4.3.16 6.535e-203 645.0
CMS2_k127_4751041_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 459.0
CMS2_k127_4751041_10 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000001124 53.0
CMS2_k127_4751041_2 pyruvate kinase activity K00873,K00958 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 446.0
CMS2_k127_4751041_3 binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 410.0
CMS2_k127_4751041_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 319.0
CMS2_k127_4751041_5 sensor histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008544 265.0
CMS2_k127_4751041_6 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000001052 252.0
CMS2_k127_4751041_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000009039 224.0
CMS2_k127_4751041_8 RNA recognition motif - - - 0.000000000000000000000000004455 115.0
CMS2_k127_4751041_9 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000003197 72.0
CMS2_k127_4763643_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 609.0
CMS2_k127_4763643_1 Belongs to the UPF0235 family K09131 - - 0.0000000000000002846 81.0
CMS2_k127_4763643_2 transferase activity, transferring glycosyl groups - - - 0.0008684 44.0
CMS2_k127_4798415_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 3.791e-239 756.0
CMS2_k127_4798415_1 GAF domain - - - 2.345e-212 686.0
CMS2_k127_4798415_10 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000006124 165.0
CMS2_k127_4798415_11 Helix-turn-helix domain - - - 0.000000000000000000000000000235 124.0
CMS2_k127_4798415_12 PFAM SCP-like extracellular - - - 0.0000004509 57.0
CMS2_k127_4798415_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 536.0
CMS2_k127_4798415_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 475.0
CMS2_k127_4798415_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 365.0
CMS2_k127_4798415_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 339.0
CMS2_k127_4798415_6 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 327.0
CMS2_k127_4798415_7 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002275 275.0
CMS2_k127_4798415_8 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000003015 260.0
CMS2_k127_4798415_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000155 196.0
CMS2_k127_482399_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 1.785e-284 881.0
CMS2_k127_482399_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 449.0
CMS2_k127_482399_2 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000005008 136.0
CMS2_k127_482399_3 PFAM blue (type 1) copper domain protein - - - 0.0000006057 59.0
CMS2_k127_4835717_0 type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 561.0
CMS2_k127_4835717_1 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 365.0
CMS2_k127_4835717_2 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000207 278.0
CMS2_k127_4835717_3 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000005826 192.0
CMS2_k127_4835717_4 Prokaryotic N-terminal methylation motif K02458 - - 0.000006919 55.0
CMS2_k127_4835717_5 Pfam:N_methyl_2 K02459 - - 0.000009476 56.0
CMS2_k127_4835717_6 General secretion pathway protein K02457 - - 0.0008169 49.0
CMS2_k127_4879723_0 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006595 259.0
CMS2_k127_4879723_1 nucleotide catabolic process - - - 0.000000000000000000000000000000000000000000000000001064 188.0
CMS2_k127_4879723_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000014 95.0
CMS2_k127_4879723_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000002785 61.0
CMS2_k127_4950228_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2127.0
CMS2_k127_4950228_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1328.0
CMS2_k127_4950228_2 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000001052 141.0
CMS2_k127_4950228_3 OsmC-like protein - - - 0.0000000000000000000000000000000001252 134.0
CMS2_k127_4950228_4 Regulatory protein, FmdB family - - - 0.0000000009836 61.0
CMS2_k127_4950228_5 OsmC-like protein - - - 0.0000000111 55.0
CMS2_k127_4952640_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.216e-259 805.0
CMS2_k127_4952640_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.519e-226 706.0
CMS2_k127_4952640_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 356.0
CMS2_k127_4952640_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000005131 158.0
CMS2_k127_4964791_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.994e-254 795.0
CMS2_k127_4964791_1 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 432.0
CMS2_k127_4964791_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 303.0
CMS2_k127_4964791_3 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000005886 176.0
CMS2_k127_5025884_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 421.0
CMS2_k127_5025884_1 metallopeptidase activity K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 344.0
CMS2_k127_5069452_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 458.0
CMS2_k127_5069452_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 361.0
CMS2_k127_5069452_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 347.0
CMS2_k127_5069452_3 PFAM cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 305.0
CMS2_k127_5069452_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000009582 111.0
CMS2_k127_5069452_5 MlaD protein K02067 - - 0.00000000000000000000906 93.0
CMS2_k127_5069452_6 - - - - 0.0000000000008059 70.0
CMS2_k127_508721_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 330.0
CMS2_k127_508721_1 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001406 274.0
CMS2_k127_508721_10 PFAM Fimbrial assembly family protein K02461,K02662,K02663,K12279,K12289 GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0009976 49.0
CMS2_k127_508721_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000002266 246.0
CMS2_k127_508721_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000001347 193.0
CMS2_k127_508721_4 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000001533 171.0
CMS2_k127_508721_5 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000001947 153.0
CMS2_k127_508721_6 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000001611 128.0
CMS2_k127_508721_7 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000001292 117.0
CMS2_k127_508721_8 Pilus assembly protein, PilP K02665 - - 0.000000000000006191 81.0
CMS2_k127_5092898_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.718e-283 881.0
CMS2_k127_5092898_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 377.0
CMS2_k127_5092898_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 357.0
CMS2_k127_5092898_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 346.0
CMS2_k127_5092898_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 327.0
CMS2_k127_5092898_5 Sporulation and spore germination - - - 0.00000000007111 70.0
CMS2_k127_5092898_6 Copper amine oxidase N-terminal domain K01448 - 3.5.1.28 0.000000007271 63.0
CMS2_k127_5108607_0 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 3.967e-195 617.0
CMS2_k127_5108607_1 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 428.0
CMS2_k127_5108607_2 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 385.0
CMS2_k127_5108607_3 Carbohydrate ABC transporter ATP-binding protein, CUT1 family K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 347.0
CMS2_k127_5108607_4 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 342.0
CMS2_k127_5108607_5 Binding-protein-dependent transport system inner membrane component K02025,K10237,K15771 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 334.0
CMS2_k127_5108607_6 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 294.0
CMS2_k127_5108607_7 PFAM FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000007727 132.0
CMS2_k127_5134570_0 PFAM Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 451.0
CMS2_k127_5174209_0 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 405.0
CMS2_k127_5174209_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 347.0
CMS2_k127_5174209_2 Peptidylprolyl isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000002693 198.0
CMS2_k127_5174209_3 PFAM Fimbrial assembly K02461 - - 0.00000000000000000000009243 113.0
CMS2_k127_5174209_4 Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB K07677 - 2.7.13.3 0.00000000000001792 78.0
CMS2_k127_5174209_5 Type II secretion system (T2SS), protein M subtype b - - - 0.0000000003746 68.0
CMS2_k127_5174209_6 Acetyltransferase (GNAT) domain - - - 0.0002535 50.0
CMS2_k127_51967_0 ferrous iron transmembrane transporter activity K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 400.0
CMS2_k127_51967_1 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000002455 106.0
CMS2_k127_5202062_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 480.0
CMS2_k127_5202062_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 439.0
CMS2_k127_5202062_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 290.0
CMS2_k127_5203840_0 DNA polymerase K02347 - - 1.868e-230 726.0
CMS2_k127_5203840_1 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006426 284.0
CMS2_k127_5203840_2 CBS domain K00974 - 2.7.7.72 0.0000000000003236 69.0
CMS2_k127_5211881_0 Protein conserved in bacteria - - - 9.438e-236 756.0
CMS2_k127_5211881_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 607.0
CMS2_k127_5211881_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 332.0
CMS2_k127_5211881_3 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000768 269.0
CMS2_k127_5211881_4 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000002154 224.0
CMS2_k127_5211881_5 lactate metabolic process K11473,K18928 - - 0.000000000000000000000000000000000000000000000000000000001149 215.0
CMS2_k127_5211881_6 Regulatory protein, FmdB family - - - 0.00000000000000287 78.0
CMS2_k127_5211881_7 PBS lyase K22221 - - 0.0000000000001737 79.0
CMS2_k127_5211881_8 PFAM CheB methylesterase K13924 - 2.1.1.80,3.1.1.61 0.0000000000009037 73.0
CMS2_k127_5236672_0 Phosphoglycerate kinase K00927 - 2.7.2.3 1.945e-198 624.0
CMS2_k127_5236672_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 479.0
CMS2_k127_5236672_2 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 293.0
CMS2_k127_5236672_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000002995 213.0
CMS2_k127_5303068_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1088.0
CMS2_k127_5303068_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000002089 241.0
CMS2_k127_5303068_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000005476 214.0
CMS2_k127_5303068_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000216 150.0
CMS2_k127_5303068_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000001678 69.0
CMS2_k127_5323974_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 542.0
CMS2_k127_5323974_1 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 389.0
CMS2_k127_5323974_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 346.0
CMS2_k127_5323974_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000001487 221.0
CMS2_k127_5323974_4 YbbR-like protein - - - 0.00000000000000000000000000000000000000000006424 168.0
CMS2_k127_5323974_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000001112 64.0
CMS2_k127_5323974_6 - - - - 0.0008731 44.0
CMS2_k127_5334470_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 3.821e-198 623.0
CMS2_k127_5334470_1 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 463.0
CMS2_k127_5334470_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000003799 203.0
CMS2_k127_5334470_11 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000003888 119.0
CMS2_k127_5334470_12 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.000000000000000000000001855 104.0
CMS2_k127_5334470_13 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000001782 89.0
CMS2_k127_5334470_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 421.0
CMS2_k127_5334470_3 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 368.0
CMS2_k127_5334470_4 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 324.0
CMS2_k127_5334470_5 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004886 276.0
CMS2_k127_5334470_6 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000174 277.0
CMS2_k127_5334470_7 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001069 273.0
CMS2_k127_5334470_8 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000236 276.0
CMS2_k127_5334470_9 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000009976 211.0
CMS2_k127_5343411_0 His Kinase A (phosphoacceptor) domain - - - 2.991e-235 739.0
CMS2_k127_5343411_1 kinase activity K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 556.0
CMS2_k127_5343411_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000001928 234.0
CMS2_k127_5349128_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 577.0
CMS2_k127_5349128_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 567.0
CMS2_k127_5349128_2 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 496.0
CMS2_k127_5349128_3 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 338.0
CMS2_k127_5349128_4 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001916 282.0
CMS2_k127_5349128_5 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000003244 159.0
CMS2_k127_5349128_6 - - - - 0.000000000000000000000000004947 114.0
CMS2_k127_5349635_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 364.0
CMS2_k127_5349635_1 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000336 244.0
CMS2_k127_5349635_2 Endonuclease containing a URI domain K07461 - - 0.00000000000000003423 85.0
CMS2_k127_5349635_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000001471 81.0
CMS2_k127_5349635_4 Pentapeptide repeats (9 copies) - - - 0.0000000000003113 79.0
CMS2_k127_5349635_5 GIY-YIG type nucleases (URI domain) K07461 - - 0.0000000000408 63.0
CMS2_k127_5351006_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 554.0
CMS2_k127_5351006_1 ferredoxin-thioredoxin reductase activity - - - 0.00000000000000000000000000000000000000003082 154.0
CMS2_k127_5351006_2 methyltransferase - - - 0.000000000000000000000000000000000000006402 153.0
CMS2_k127_5351006_4 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.0000000000000000000000004659 106.0
CMS2_k127_537004_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 1.447e-205 645.0
CMS2_k127_537004_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 519.0
CMS2_k127_537004_2 transcription factor binding K11527 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 492.0
CMS2_k127_537004_3 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 317.0
CMS2_k127_537004_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 301.0
CMS2_k127_537004_5 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000001473 213.0
CMS2_k127_537004_6 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000002697 209.0
CMS2_k127_537004_7 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000872 178.0
CMS2_k127_537004_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000001397 69.0
CMS2_k127_5404579_0 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 1.633e-210 671.0
CMS2_k127_5404579_1 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 553.0
CMS2_k127_5404579_2 DRTGG domain protein K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 338.0
CMS2_k127_5404579_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000001015 213.0
CMS2_k127_5404579_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000005629 198.0
CMS2_k127_5404579_5 Transcriptional regulator K02529 - - 0.000000000000000001431 91.0
CMS2_k127_5404579_6 - - - - 0.0000006241 59.0
CMS2_k127_5420137_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000007397 234.0
CMS2_k127_5420137_1 DnaJ molecular chaperone homology domain K05516 - - 0.0000000000000000000000000000000000000000000005663 174.0
CMS2_k127_5420137_2 - - - - 0.000148 51.0
CMS2_k127_5431080_0 Ftsk_gamma K03466 - - 4.656e-201 649.0
CMS2_k127_5431080_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000006834 265.0
CMS2_k127_5431080_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000004102 216.0
CMS2_k127_5431080_3 Transposase IS200 like K07491 - - 0.00000000000003901 72.0
CMS2_k127_5431080_4 Transposase IS200 like K07491 - - 0.0000931 46.0
CMS2_k127_5440375_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 591.0
CMS2_k127_5440375_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 498.0
CMS2_k127_5440375_2 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003421 263.0
CMS2_k127_5440375_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000002987 249.0
CMS2_k127_5440375_4 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001632 163.0
CMS2_k127_5440375_5 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000006704 151.0
CMS2_k127_5440375_6 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000000007999 121.0
CMS2_k127_5440375_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000002723 111.0
CMS2_k127_5464597_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 503.0
CMS2_k127_5464597_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 483.0
CMS2_k127_5464597_10 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000009136 132.0
CMS2_k127_5464597_11 SMART Cold shock protein K03704 - - 0.0000000000000000000000000001448 116.0
CMS2_k127_5464597_12 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000003221 116.0
CMS2_k127_5464597_13 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000005491 105.0
CMS2_k127_5464597_14 Protein of unknown function (DUF2905) - - - 0.000000000000000000001377 96.0
CMS2_k127_5464597_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 452.0
CMS2_k127_5464597_3 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 400.0
CMS2_k127_5464597_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 357.0
CMS2_k127_5464597_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001629 269.0
CMS2_k127_5464597_6 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003052 271.0
CMS2_k127_5464597_7 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.000000000000000000000000000000000000000000000000000000000007702 212.0
CMS2_k127_5464597_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000005812 208.0
CMS2_k127_5464597_9 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.000000000000000000000000000000000000000000000000000007145 196.0
CMS2_k127_5470874_0 Glycosyl hydrolase family 65 central catalytic domain protein K00691,K05342 - 2.4.1.64,2.4.1.8 0.0 1039.0
CMS2_k127_5470874_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 4.714e-229 722.0
CMS2_k127_5470874_2 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 384.0
CMS2_k127_5470874_3 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000003774 89.0
CMS2_k127_5470874_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00001866 48.0
CMS2_k127_5483001_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 361.0
CMS2_k127_5483001_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001458 271.0
CMS2_k127_5483001_2 Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000000000000000001888 198.0
CMS2_k127_551921_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.181e-211 664.0
CMS2_k127_551921_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000002661 205.0
CMS2_k127_551921_2 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000001177 62.0
CMS2_k127_5571993_0 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 548.0
CMS2_k127_5571993_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 513.0
CMS2_k127_5571993_2 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 464.0
CMS2_k127_5571993_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 423.0
CMS2_k127_5571993_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000007204 228.0
CMS2_k127_5571993_5 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000007668 131.0
CMS2_k127_5571993_6 RDD family - - - 0.000000000000000000000000002044 116.0
CMS2_k127_5571993_7 TIGRFAM rod shape-determining protein MreD K03571 - - 0.000000003648 64.0
CMS2_k127_5584683_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 8.706e-202 636.0
CMS2_k127_5584683_1 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000001094 199.0
CMS2_k127_5600482_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 431.0
CMS2_k127_5600482_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 364.0
CMS2_k127_5600482_2 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000003555 217.0
CMS2_k127_5600482_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000004902 207.0
CMS2_k127_5600482_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000004072 208.0
CMS2_k127_5600482_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000001999 173.0
CMS2_k127_5600482_6 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000002529 170.0
CMS2_k127_5635947_0 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 404.0
CMS2_k127_5635947_1 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 387.0
CMS2_k127_5635947_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001985 278.0
CMS2_k127_5635947_3 HypF finger K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002549 275.0
CMS2_k127_5635947_4 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000001886 138.0
CMS2_k127_5635947_5 acetyl-CoA catabolic process K00197,K03616 - 2.1.1.245 0.000000000000000000000009953 108.0
CMS2_k127_5691129_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 4.163e-234 727.0
CMS2_k127_5691129_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.18e-196 619.0
CMS2_k127_5691129_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 552.0
CMS2_k127_5691129_3 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 439.0
CMS2_k127_5691129_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 318.0
CMS2_k127_5691129_5 ribonuclease III activity K03685,K07053 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3,3.1.3.97 0.00000000000000000000000000000000000000000000000000000001815 205.0
CMS2_k127_5691129_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000478 126.0
CMS2_k127_5692723_0 COG0058 Glucan phosphorylase - - - 8.279e-260 811.0
CMS2_k127_5692723_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 589.0
CMS2_k127_5692723_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 521.0
CMS2_k127_5692723_3 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 294.0
CMS2_k127_5692723_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005244 243.0
CMS2_k127_5692723_5 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000525 200.0
CMS2_k127_5692723_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000004291 169.0
CMS2_k127_5692723_7 SMART Cold shock protein K03704 - - 0.0000000000000000000000000009203 113.0
CMS2_k127_5692723_8 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000000004183 97.0
CMS2_k127_5695850_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005804 252.0
CMS2_k127_5695850_1 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000677 243.0
CMS2_k127_5695850_2 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000001769 157.0
CMS2_k127_5695850_3 Unusual protein kinase - - - 0.000000000000000000004393 96.0
CMS2_k127_5695850_4 PFAM YHS domain - - - 0.0000000002189 62.0
CMS2_k127_5759845_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.027e-229 719.0
CMS2_k127_5759845_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 297.0
CMS2_k127_5759845_2 Bacterial type II and III secretion system protein K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008655 280.0
CMS2_k127_5759845_3 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000003402 251.0
CMS2_k127_5759845_4 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000002974 233.0
CMS2_k127_5759845_5 glycosyl transferase family 2 K00786 - - 0.000000000000000000000000000004446 122.0
CMS2_k127_5759845_6 Glycosyltransferase like family K20444 - - 0.000000008059 69.0
CMS2_k127_5769207_0 Aminotransferase class-III K01845 - 5.4.3.8 5.037e-201 634.0
CMS2_k127_5769207_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 576.0
CMS2_k127_5769207_11 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000001843 223.0
CMS2_k127_5769207_12 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000004886 216.0
CMS2_k127_5769207_13 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000003699 214.0
CMS2_k127_5769207_14 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000002531 177.0
CMS2_k127_5769207_15 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000006609 190.0
CMS2_k127_5769207_16 Dolichyl-phosphate-mannose-protein mannosyltransferase - GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008378,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000007738 169.0
CMS2_k127_5769207_17 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000005314 148.0
CMS2_k127_5769207_18 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000231 136.0
CMS2_k127_5769207_19 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000001567 134.0
CMS2_k127_5769207_2 ABC transporter transmembrane region K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 518.0
CMS2_k127_5769207_20 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000005905 136.0
CMS2_k127_5769207_21 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000573 101.0
CMS2_k127_5769207_22 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000000000000000003273 99.0
CMS2_k127_5769207_23 amino acid activation for nonribosomal peptide biosynthetic process K06045 - 4.2.1.129,5.4.99.17 0.00000000000009297 83.0
CMS2_k127_5769207_25 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000003955 58.0
CMS2_k127_5769207_26 response regulator - - - 0.00004662 53.0
CMS2_k127_5769207_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 417.0
CMS2_k127_5769207_4 Glycosyl transferases group 1 K02844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 411.0
CMS2_k127_5769207_5 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 349.0
CMS2_k127_5769207_6 membrane K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 325.0
CMS2_k127_5769207_7 Thiamine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 308.0
CMS2_k127_5769207_8 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 293.0
CMS2_k127_5769207_9 Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core K02848 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002307 270.0
CMS2_k127_5793892_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.296e-213 673.0
CMS2_k127_5793892_1 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001347 290.0
CMS2_k127_5793892_10 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000009833 96.0
CMS2_k127_5793892_11 Domain of unknown function (DUF4136) - - - 0.000000000000000000001214 101.0
CMS2_k127_5793892_12 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000003401 80.0
CMS2_k127_5793892_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000007724 79.0
CMS2_k127_5793892_14 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000007037 50.0
CMS2_k127_5793892_15 - - - - 0.00000142 52.0
CMS2_k127_5793892_2 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002306 276.0
CMS2_k127_5793892_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002899 245.0
CMS2_k127_5793892_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000006747 204.0
CMS2_k127_5793892_5 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000009877 184.0
CMS2_k127_5793892_6 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000003781 172.0
CMS2_k127_5793892_7 PFAM regulatory protein TetR K13770 - - 0.000000000000000000000000000000000000066 150.0
CMS2_k127_5793892_8 sequence-specific DNA binding K18830 - - 0.0000000000000000000000000001205 122.0
CMS2_k127_5793892_9 PIN domain - - - 0.00000000000000000000000003726 112.0
CMS2_k127_5839971_0 PFAM Radical SAM - - - 5.831e-234 736.0
CMS2_k127_5839971_1 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000003421 227.0
CMS2_k127_5839971_2 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000004814 168.0
CMS2_k127_5839971_3 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039 - - 0.0000000000000000000000000000000000000007271 150.0
CMS2_k127_5839971_4 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.000000000000000000000284 100.0
CMS2_k127_5842313_0 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 390.0
CMS2_k127_5842313_1 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.00000000000000000000000496 112.0
CMS2_k127_5847734_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 503.0
CMS2_k127_5847734_1 cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 461.0
CMS2_k127_5847734_10 Domain of unknown function (DUF4398) - - - 0.000000000000000000000000000000000000000000000000000001138 207.0
CMS2_k127_5847734_11 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000000001146 126.0
CMS2_k127_5847734_12 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000003068 131.0
CMS2_k127_5847734_13 Domain of unknown function (DUF4398) - - - 0.00000000000003236 77.0
CMS2_k127_5847734_15 methyltransferase - - - 0.00007543 51.0
CMS2_k127_5847734_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 463.0
CMS2_k127_5847734_3 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 452.0
CMS2_k127_5847734_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 336.0
CMS2_k127_5847734_5 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 312.0
CMS2_k127_5847734_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 295.0
CMS2_k127_5847734_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005994 277.0
CMS2_k127_5847734_8 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007919 259.0
CMS2_k127_5847734_9 phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004287 243.0
CMS2_k127_5849427_0 carbon starvation protein CstA K06200 - - 1.645e-309 958.0
CMS2_k127_5849427_1 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000006987 239.0
CMS2_k127_5849427_2 NTPase - - - 0.000000000000000000000000000000000000000000000000000002911 195.0
CMS2_k127_5849427_3 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000191 173.0
CMS2_k127_5849427_4 - - - - 0.00000000000000001014 89.0
CMS2_k127_5849427_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0001189 54.0
CMS2_k127_5864013_0 FAD binding domain K00394 - 1.8.99.2 0.0 1026.0
CMS2_k127_5864013_1 Methyl-viologen-reducing hydrogenase, delta subunit K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1009.0
CMS2_k127_5864013_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 550.0
CMS2_k127_5864013_3 FAD dependent oxidoreductase K16885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 538.0
CMS2_k127_5864013_4 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 407.0
CMS2_k127_5864013_5 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000007499 249.0
CMS2_k127_5864013_6 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000001479 228.0
CMS2_k127_5864013_7 - - - - 0.00000000000000000000000000000000001286 137.0
CMS2_k127_5873164_0 mechanosensitive ion channel activity - - - 5.189e-207 650.0
CMS2_k127_5873164_1 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 523.0
CMS2_k127_5873164_10 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00002443 47.0
CMS2_k127_5873164_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 458.0
CMS2_k127_5873164_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 315.0
CMS2_k127_5873164_4 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000001108 205.0
CMS2_k127_5873164_5 ORF6N domain - - - 0.00000000000000000000000000000000000000000000000000009204 191.0
CMS2_k127_5873164_6 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000009825 205.0
CMS2_k127_5873164_7 CRISPR associated protein Cas2 K09951 - - 0.000000000000000000000000000000000000000000001699 165.0
CMS2_k127_5873164_8 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000001675 124.0
CMS2_k127_5873164_9 Lamin Tail Domain - - - 0.00000000000000006996 94.0
CMS2_k127_5921134_0 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 534.0
CMS2_k127_5921134_1 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 499.0
CMS2_k127_5921134_10 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000261 68.0
CMS2_k127_5921134_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 488.0
CMS2_k127_5921134_3 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 347.0
CMS2_k127_5921134_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 303.0
CMS2_k127_5921134_5 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000001651 227.0
CMS2_k127_5921134_6 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000003315 216.0
CMS2_k127_5921134_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000005665 174.0
CMS2_k127_5921134_8 protein conserved in bacteria - - - 0.000000000000000000000000000000000004556 142.0
CMS2_k127_5921134_9 PFAM RNA recognition motif - - - 0.0000000000000000000000000002593 117.0
CMS2_k127_5941341_0 Uncharacterized protein family (UPF0051) K07033 - - 1.026e-194 615.0
CMS2_k127_5941341_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 376.0
CMS2_k127_5941341_2 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000003892 162.0
CMS2_k127_5956742_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 601.0
CMS2_k127_5956742_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 424.0
CMS2_k127_5956742_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000004668 178.0
CMS2_k127_5956742_3 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000005417 138.0
CMS2_k127_5997183_0 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 503.0
CMS2_k127_5997183_1 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000009484 217.0
CMS2_k127_5997183_2 Nitroreductase K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000001108 162.0
CMS2_k127_5997183_3 Nitroreductase K04719 - 1.13.11.79 0.0000000000000000000000000000008052 123.0
CMS2_k127_6023067_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 539.0
CMS2_k127_6023067_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.0000000000000000000000000000000000000000000000000000009918 196.0
CMS2_k127_6045349_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.057e-272 846.0
CMS2_k127_6045349_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.846e-253 789.0
CMS2_k127_6045349_2 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 591.0
CMS2_k127_6045349_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 477.0
CMS2_k127_6045349_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 317.0
CMS2_k127_6045349_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000002805 194.0
CMS2_k127_6045349_6 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000002346 164.0
CMS2_k127_6045349_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000001561 140.0
CMS2_k127_6045349_8 (Rhomboid) family - - - 0.00000000000000000000133 96.0
CMS2_k127_6045349_9 Protein of unknown function (DUF2934) - - - 0.000001531 56.0
CMS2_k127_6048756_0 Conserved region in glutamate synthase - - - 3.514e-228 717.0
CMS2_k127_6048756_1 NADH dehydrogenase - - - 3.464e-227 715.0
CMS2_k127_6048756_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 349.0
CMS2_k127_6048756_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000006432 173.0
CMS2_k127_6048756_4 Domain of unknown function DUF128 K09720 - - 0.00000004088 55.0
CMS2_k127_6048756_5 PFAM 4Fe-4S ferredoxin, iron-sulphur binding, subgroup K07307 - - 0.0002801 46.0
CMS2_k127_6056647_0 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 555.0
CMS2_k127_6056647_1 phosphorelay sensor kinase activity K03320,K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 403.0
CMS2_k127_6056647_2 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 387.0
CMS2_k127_6056647_3 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000001737 207.0
CMS2_k127_6056647_4 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000000000000000000000001055 182.0
CMS2_k127_6056647_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000000002649 179.0
CMS2_k127_6056647_6 lysyltransferase activity K07027 - - 0.00000000000000000000000000001703 125.0
CMS2_k127_6057610_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 5.831e-234 736.0
CMS2_k127_6057610_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 512.0
CMS2_k127_6057610_10 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.0000000000000000000000001656 109.0
CMS2_k127_6057610_11 Regulatory protein RecX K03565 - - 0.000000000000001411 82.0
CMS2_k127_6057610_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000007494 74.0
CMS2_k127_6057610_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 484.0
CMS2_k127_6057610_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 334.0
CMS2_k127_6057610_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 331.0
CMS2_k127_6057610_5 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001933 273.0
CMS2_k127_6057610_6 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000004476 218.0
CMS2_k127_6057610_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000002713 144.0
CMS2_k127_6057610_8 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000008809 128.0
CMS2_k127_6057610_9 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000000001229 116.0
CMS2_k127_6079467_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 393.0
CMS2_k127_6079467_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000004097 240.0
CMS2_k127_6079467_2 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K06950 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000003639 228.0
CMS2_k127_6079467_3 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000102 172.0
CMS2_k127_6079467_4 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000005728 121.0
CMS2_k127_6085922_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1082.0
CMS2_k127_6085922_1 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001847 251.0
CMS2_k127_6085922_2 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000004237 153.0
CMS2_k127_6085922_3 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000000000000000000006979 124.0
CMS2_k127_6088922_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 3.603e-253 797.0
CMS2_k127_6088922_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 4.86e-222 718.0
CMS2_k127_6088922_2 tigr00255 - - - 0.000000000000000000000000000000000000000000000000000000000002872 218.0
CMS2_k127_6088922_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000001212 212.0
CMS2_k127_6088922_4 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000000007666 115.0
CMS2_k127_6163413_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1288.0
CMS2_k127_6163413_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 512.0
CMS2_k127_6163413_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000857 261.0
CMS2_k127_6163413_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000001371 214.0
CMS2_k127_6163413_4 - - - - 0.00000001946 57.0
CMS2_k127_61728_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 1.706e-202 649.0
CMS2_k127_61728_1 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004017 253.0
CMS2_k127_61728_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000004094 202.0
CMS2_k127_61728_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000001476 176.0
CMS2_k127_61728_4 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000138 158.0
CMS2_k127_6183323_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 511.0
CMS2_k127_6183323_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 290.0
CMS2_k127_6183323_2 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.00000000000000006234 81.0
CMS2_k127_6185894_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 571.0
CMS2_k127_6185894_1 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006497 246.0
CMS2_k127_6185894_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000005681 228.0
CMS2_k127_6185894_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000423 194.0
CMS2_k127_6185894_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000006399 151.0
CMS2_k127_6185894_5 RNA recognition motif - - - 0.000000000000000000000001583 106.0
CMS2_k127_6185894_6 deoxyhypusine monooxygenase activity K05386 - - 0.000000000000000004235 89.0
CMS2_k127_6185894_7 - - - - 0.000000000000005225 76.0
CMS2_k127_6185894_8 - - - - 0.00001502 48.0
CMS2_k127_6236772_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 8.803e-247 765.0
CMS2_k127_6236772_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 345.0
CMS2_k127_6236772_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 290.0
CMS2_k127_6270654_0 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 564.0
CMS2_k127_6270654_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001151 246.0
CMS2_k127_6270654_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000005622 202.0
CMS2_k127_6270654_3 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000001665 99.0
CMS2_k127_6270654_4 TIGRFAM alpha-glucan - - - 0.000000000000001115 77.0
CMS2_k127_6291429_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 588.0
CMS2_k127_6291429_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 308.0
CMS2_k127_6291429_2 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001026 244.0
CMS2_k127_6291429_3 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000001376 221.0
CMS2_k127_6291429_4 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000158 203.0
CMS2_k127_6367831_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 4.601e-227 717.0
CMS2_k127_6367831_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000003745 81.0
CMS2_k127_6367831_2 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.000001856 54.0
CMS2_k127_6382760_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009961 248.0
CMS2_k127_6382760_1 phosphorelay signal transduction system K13599 - - 0.000000000000000000000000000000000009713 154.0
CMS2_k127_6382760_2 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.00000000000000000000000000000000001301 154.0
CMS2_k127_6382760_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000001974 120.0
CMS2_k127_6415976_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 4.242e-204 655.0
CMS2_k127_6415976_1 Mur ligase family, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 339.0
CMS2_k127_6415976_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001759 281.0
CMS2_k127_6415976_3 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000000000000001042 153.0
CMS2_k127_6415976_4 - K07275 - - 0.000000000000000000000001813 111.0
CMS2_k127_6427402_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.089e-303 940.0
CMS2_k127_6427402_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 380.0
CMS2_k127_6464218_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1258.0
CMS2_k127_6464218_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 501.0
CMS2_k127_6471341_0 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 415.0
CMS2_k127_6484376_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 514.0
CMS2_k127_6484376_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 450.0
CMS2_k127_6484376_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 311.0
CMS2_k127_6484376_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 302.0
CMS2_k127_6484376_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004105 280.0
CMS2_k127_6484376_5 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000002021 93.0
CMS2_k127_6484376_6 Glutaredoxin K03676 - - 0.0000000000000003099 79.0
CMS2_k127_6491360_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 441.0
CMS2_k127_6491360_1 Dehydrogenase E1 component K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 432.0
CMS2_k127_6491360_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 348.0
CMS2_k127_6491360_3 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000002619 235.0
CMS2_k127_6491360_4 Adenylylsulphate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000000000000001529 156.0
CMS2_k127_6491360_5 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000002369 130.0
CMS2_k127_6491360_6 - - - - 0.000000000000000001046 91.0
CMS2_k127_6502574_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 318.0
CMS2_k127_6502574_1 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.000000000000000000000000000000000000000000000000000000002205 210.0
CMS2_k127_6502574_2 the in vivo substrate is - - - 0.0000000000000000000000000000000000000000000000000000009876 202.0
CMS2_k127_6502574_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000004763 165.0
CMS2_k127_6502574_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000003896 158.0
CMS2_k127_650587_0 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000001294 199.0
CMS2_k127_650587_1 - - - - 0.00000000000000000000000000000000000000004047 158.0
CMS2_k127_650587_2 spectrin binding - - - 0.00000000000000000005165 96.0
CMS2_k127_6558401_0 Heavy-metal-associated domain K01533 - 3.6.3.4 0.0 1073.0
CMS2_k127_6558401_1 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 9.567e-210 658.0
CMS2_k127_6558401_10 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134,K00150,K03340 - 1.2.1.12,1.2.1.59,1.4.1.16 0.000000000000000000000000000000000003091 141.0
CMS2_k127_6558401_11 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000002254 134.0
CMS2_k127_6558401_13 Protein of unknown function (DUF1622) - - - 0.00000000000000000000000000531 113.0
CMS2_k127_6558401_14 Thioredoxin domain - - - 0.0000000000000000000000009674 106.0
CMS2_k127_6558401_15 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.0000000000000000000008152 99.0
CMS2_k127_6558401_16 - - - - 0.0000000019 67.0
CMS2_k127_6558401_17 - - - - 0.0000008616 54.0
CMS2_k127_6558401_2 Unusual protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 443.0
CMS2_k127_6558401_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 416.0
CMS2_k127_6558401_4 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 381.0
CMS2_k127_6558401_5 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 297.0
CMS2_k127_6558401_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000003004 257.0
CMS2_k127_6558401_7 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000002583 232.0
CMS2_k127_6558401_8 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000007269 180.0
CMS2_k127_6558401_9 Cytochrome P460 - - - 0.00000000000000000000000000000000000000001069 160.0
CMS2_k127_6571957_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 0.0 1034.0
CMS2_k127_6571957_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 549.0
CMS2_k127_6571957_10 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000001903 214.0
CMS2_k127_6571957_11 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000284 207.0
CMS2_k127_6571957_12 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000456 190.0
CMS2_k127_6571957_13 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000007365 186.0
CMS2_k127_6571957_14 Thioredoxin domain - - - 0.000000000000000000000000000000000000000008793 157.0
CMS2_k127_6571957_15 PFAM Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000003595 130.0
CMS2_k127_6571957_16 ATP synthase K02115 - - 0.000000000000000000002838 104.0
CMS2_k127_6571957_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000002319 93.0
CMS2_k127_6571957_18 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000001054 100.0
CMS2_k127_6571957_19 alkyl hydroperoxide reductase activity - - - 0.000000000000000004262 85.0
CMS2_k127_6571957_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 540.0
CMS2_k127_6571957_21 Produces ATP from ADP in the presence of a proton gradient across the membrane - - - 0.0000000000006889 74.0
CMS2_k127_6571957_3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 529.0
CMS2_k127_6571957_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 512.0
CMS2_k127_6571957_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 473.0
CMS2_k127_6571957_6 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 327.0
CMS2_k127_6571957_7 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 293.0
CMS2_k127_6571957_8 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002095 276.0
CMS2_k127_6571957_9 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000002965 243.0
CMS2_k127_6605754_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 347.0
CMS2_k127_6605754_1 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000001961 195.0
CMS2_k127_6605754_2 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000001778 143.0
CMS2_k127_6605754_3 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000001094 80.0
CMS2_k127_6605754_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000002726 56.0
CMS2_k127_6647020_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1070.0
CMS2_k127_6647020_1 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000005464 159.0
CMS2_k127_665018_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1154.0
CMS2_k127_665018_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 1.272e-314 969.0
CMS2_k127_665018_2 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 558.0
CMS2_k127_665018_3 PFAM Glutamine amidotransferase, class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000001885 245.0
CMS2_k127_665018_4 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000005885 169.0
CMS2_k127_665018_5 Archaeal transcriptional regulator TrmB - - - 0.00000000000259 71.0
CMS2_k127_6676335_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 497.0
CMS2_k127_6676335_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 361.0
CMS2_k127_6676335_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000004973 160.0
CMS2_k127_6676335_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000002065 141.0
CMS2_k127_6676335_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000002002 62.0
CMS2_k127_671246_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.749e-217 677.0
CMS2_k127_671246_1 PFAM phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 521.0
CMS2_k127_671246_2 deoxyribose-phosphate aldolase activity K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000002813 232.0
CMS2_k127_671246_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000005578 129.0
CMS2_k127_671246_4 Belongs to the UPF0758 family K03630 - - 0.0000000001038 65.0
CMS2_k127_6726706_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 591.0
CMS2_k127_6726706_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003595 273.0
CMS2_k127_6726706_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000001035 220.0
CMS2_k127_6731445_0 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 293.0
CMS2_k127_6731445_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002595 272.0
CMS2_k127_6731445_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000009059 136.0
CMS2_k127_6753695_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 425.0
CMS2_k127_6753695_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000007618 252.0
CMS2_k127_6753695_2 metallopeptidase activity K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000028 250.0
CMS2_k127_6753695_3 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000000000000000004294 177.0
CMS2_k127_6782_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1783.0
CMS2_k127_6782_1 Conserved region in glutamate synthase - - - 1.807e-276 857.0
CMS2_k127_6782_2 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 400.0
CMS2_k127_6782_3 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 387.0
CMS2_k127_6782_4 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000119 276.0
CMS2_k127_6790966_0 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 478.0
CMS2_k127_6790966_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000001462 162.0
CMS2_k127_6793971_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 606.0
CMS2_k127_6793971_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004307 282.0
CMS2_k127_6798301_0 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 519.0
CMS2_k127_6798301_1 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 331.0
CMS2_k127_6798301_2 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 319.0
CMS2_k127_6798301_3 Type II secretion system protein B K02451 - - 0.0000000000008375 69.0
CMS2_k127_6853645_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 1.312e-236 745.0
CMS2_k127_6853645_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 289.0
CMS2_k127_6853645_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000008545 224.0
CMS2_k127_6853645_3 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000006168 225.0
CMS2_k127_6853645_4 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000499 172.0
CMS2_k127_6853645_5 Major Facilitator Superfamily - - - 0.00001841 52.0
CMS2_k127_6863188_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 440.0
CMS2_k127_6863188_1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 379.0
CMS2_k127_6863188_2 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 293.0
CMS2_k127_6863188_3 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000478 266.0
CMS2_k127_6863188_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000008947 210.0
CMS2_k127_6863188_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000001286 94.0
CMS2_k127_6863188_6 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000001182 74.0
CMS2_k127_6863188_7 - - - - 0.00002705 47.0
CMS2_k127_6864322_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.693e-273 856.0
CMS2_k127_6864322_1 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 475.0
CMS2_k127_6864322_10 Protein of unknown function (DUF2442) - - - 0.000000000000001004 79.0
CMS2_k127_6864322_11 Glycosyltransferase like family 2 - - - 0.0000000000001196 72.0
CMS2_k127_6864322_12 - - - - 0.00000000003562 74.0
CMS2_k127_6864322_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 401.0
CMS2_k127_6864322_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 340.0
CMS2_k127_6864322_4 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 340.0
CMS2_k127_6864322_5 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 331.0
CMS2_k127_6864322_6 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 295.0
CMS2_k127_6864322_7 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000217 252.0
CMS2_k127_6864322_8 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000000000000000000000002347 166.0
CMS2_k127_6864322_9 - - - - 0.00000000000000000000000973 105.0
CMS2_k127_6895174_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 508.0
CMS2_k127_6895174_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 425.0
CMS2_k127_6895174_2 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 366.0
CMS2_k127_6895174_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 314.0
CMS2_k127_6895174_4 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 281.0
CMS2_k127_6895174_5 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000005946 218.0
CMS2_k127_6895174_6 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000002908 113.0
CMS2_k127_6895174_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000006097 50.0
CMS2_k127_6931771_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 440.0
CMS2_k127_6931771_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 428.0
CMS2_k127_6931771_2 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 353.0
CMS2_k127_6931771_3 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000005169 235.0
CMS2_k127_6931771_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000001924 145.0
CMS2_k127_6931771_5 Stringent starvation protein B K09985 - - 0.00000000000000001483 88.0
CMS2_k127_6946553_0 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 560.0
CMS2_k127_6946553_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 515.0
CMS2_k127_6946553_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 400.0
CMS2_k127_6946553_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000009327 237.0
CMS2_k127_6946553_4 - - - - 0.0000000000000000000000000000000283 131.0
CMS2_k127_6969330_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 518.0
CMS2_k127_6969330_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 371.0
CMS2_k127_6969330_10 PFAM CheW domain protein K03408 - - 0.0000000000000000000006985 104.0
CMS2_k127_6969330_11 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000009444 90.0
CMS2_k127_6969330_12 Cupin 2, conserved barrel domain protein - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0030145,GO:0033609,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046564,GO:0046872,GO:0046914,GO:0046983,GO:0071704 - 0.000005885 53.0
CMS2_k127_6969330_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 332.0
CMS2_k127_6969330_3 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 290.0
CMS2_k127_6969330_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001749 304.0
CMS2_k127_6969330_5 HEAT repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008698 282.0
CMS2_k127_6969330_6 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000000000000000000000000000001083 169.0
CMS2_k127_6969330_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000002986 151.0
CMS2_k127_6969330_8 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000003391 140.0
CMS2_k127_6969330_9 PFAM CheW-like domain K03408 - - 0.00000000000000000000000000000000003142 139.0
CMS2_k127_7008660_0 Uncharacterized protein family (UPF0051) K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 347.0
CMS2_k127_7008660_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000003271 259.0
CMS2_k127_7008660_2 PFAM ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000006335 236.0
CMS2_k127_7008660_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000273 168.0
CMS2_k127_7008660_4 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000001313 57.0
CMS2_k127_7051739_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.238e-299 930.0
CMS2_k127_7051739_1 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001559 279.0
CMS2_k127_713339_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 364.0
CMS2_k127_713339_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 315.0
CMS2_k127_726381_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 404.0
CMS2_k127_726381_1 Protein of unknown function (DUF3124) - - - 0.0000000000000000000000000000000000000000000002344 172.0
CMS2_k127_746055_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 2.278e-244 760.0
CMS2_k127_746055_1 Transposase IS200 like K07491 - - 0.000000000001257 71.0
CMS2_k127_746055_2 PFAM Nitrogen regulatory protein P-II K04751,K04752 - - 0.000000008071 56.0
CMS2_k127_783936_0 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 2.149e-223 716.0
CMS2_k127_783936_1 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000007732 239.0
CMS2_k127_794713_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 478.0
CMS2_k127_794713_1 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000007072 171.0
CMS2_k127_795504_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.584e-236 742.0
CMS2_k127_795504_1 General secretory system II, protein E domain protein K02454 - - 1.317e-201 644.0
CMS2_k127_795504_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000193 287.0
CMS2_k127_795504_3 ABC-type multidrug transport system ATPase K01990,K11050 - - 0.00000000000000000000000000000000000000000001825 164.0
CMS2_k127_795504_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000008292 141.0
CMS2_k127_795504_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000002267 96.0
CMS2_k127_798505_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 543.0
CMS2_k127_798505_1 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 396.0
CMS2_k127_798505_2 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 302.0
CMS2_k127_801145_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 484.0
CMS2_k127_801145_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 402.0
CMS2_k127_801145_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 310.0
CMS2_k127_801145_3 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001123 249.0
CMS2_k127_801145_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000349 214.0
CMS2_k127_801145_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000001635 208.0
CMS2_k127_806142_0 metallopeptidase activity K03568 - - 7.282e-199 629.0
CMS2_k127_806142_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 368.0
CMS2_k127_806142_2 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000007346 165.0
CMS2_k127_806142_3 metallopeptidase activity K03592 - - 0.0000000000000000000000000002706 117.0
CMS2_k127_815918_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1343.0
CMS2_k127_815918_1 glycosyl transferase family 2 K21349 - 2.4.1.268 2.618e-195 621.0
CMS2_k127_815918_2 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001798 256.0
CMS2_k127_815918_3 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000002788 196.0
CMS2_k127_815918_4 - - - - 0.00000000000000000000000000000000000000000000003388 174.0
CMS2_k127_816668_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity K03182 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 392.0
CMS2_k127_816668_1 anaphase-promoting complex-dependent catabolic process - - - 0.0000000000000000000000000000000000000000000003396 171.0
CMS2_k127_816668_2 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000004574 123.0
CMS2_k127_816668_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000006391 116.0
CMS2_k127_816668_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000002243 106.0
CMS2_k127_816668_5 Belongs to the 'phage' integrase family - - - 0.00004337 46.0
CMS2_k127_828221_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 1.337e-223 702.0
CMS2_k127_828221_1 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 378.0
CMS2_k127_828221_2 TrkA-N domain K03455,K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 367.0
CMS2_k127_842973_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 448.0
CMS2_k127_842973_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 430.0
CMS2_k127_842973_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 413.0
CMS2_k127_842973_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 362.0
CMS2_k127_842973_4 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000001981 214.0
CMS2_k127_842973_5 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000002413 171.0
CMS2_k127_842973_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000003007 167.0
CMS2_k127_842973_7 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000000004748 127.0
CMS2_k127_842973_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000002675 88.0
CMS2_k127_845732_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.671e-245 763.0
CMS2_k127_845732_1 acetyl-CoA carboxylase, biotin carboxylase K01965 - 6.4.1.3 1.68e-245 764.0
CMS2_k127_845732_10 Virulence factor BrkB - - - 0.00000000009335 72.0
CMS2_k127_845732_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.481e-218 683.0
CMS2_k127_845732_3 Conserved carboxylase domain K01958 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 428.0
CMS2_k127_845732_4 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 457.0
CMS2_k127_845732_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 407.0
CMS2_k127_845732_6 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 298.0
CMS2_k127_845732_7 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000005379 183.0
CMS2_k127_845732_8 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000156 159.0
CMS2_k127_845732_9 - - - - 0.000000000000000000001777 101.0
CMS2_k127_849977_0 Glycosyl hydrolase family 57 - - - 3.102e-228 727.0
CMS2_k127_849977_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 421.0
CMS2_k127_849977_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 356.0
CMS2_k127_849977_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000003175 179.0
CMS2_k127_849977_4 cell cycle K05589,K12065,K13052 - - 0.000000000000001537 80.0
CMS2_k127_850921_0 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 478.0
CMS2_k127_850921_1 Mechanosensitive ion channel K03442 - - 0.00000000000000002581 84.0
CMS2_k127_854314_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1009.0
CMS2_k127_854314_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000006876 90.0
CMS2_k127_860764_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 2.647e-257 802.0
CMS2_k127_860764_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 485.0
CMS2_k127_875104_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000844 240.0
CMS2_k127_875104_1 YtkA-like - - - 0.0000000002306 66.0
CMS2_k127_881330_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 446.0
CMS2_k127_881330_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 375.0
CMS2_k127_881330_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 336.0
CMS2_k127_881330_3 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000001006 115.0
CMS2_k127_881330_4 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000009754 95.0
CMS2_k127_890698_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 485.0
CMS2_k127_890698_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 335.0
CMS2_k127_890698_10 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000008397 112.0
CMS2_k127_890698_11 peptidylprolyl isomerase K03769,K07533 - 5.2.1.8 0.0000000000000000005106 98.0
CMS2_k127_890698_12 translation initiation factor activity - - - 0.00000003608 61.0
CMS2_k127_890698_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003375 264.0
CMS2_k127_890698_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000008675 237.0
CMS2_k127_890698_4 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000004676 216.0
CMS2_k127_890698_5 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000003018 209.0
CMS2_k127_890698_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000001444 216.0
CMS2_k127_890698_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000004735 197.0
CMS2_k127_890698_8 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.00000000000000000000000000000000000000000000004965 176.0
CMS2_k127_890698_9 GAF domain - - - 0.00000000000000000000000000000000000008611 156.0
CMS2_k127_914943_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 8.962e-289 895.0
CMS2_k127_914943_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 4.074e-267 833.0
CMS2_k127_914943_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 6.863e-237 743.0
CMS2_k127_914943_3 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 565.0
CMS2_k127_914943_4 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 499.0
CMS2_k127_914943_5 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 380.0
CMS2_k127_914943_6 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 381.0
CMS2_k127_914943_7 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
CMS2_k127_914943_8 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000008794 198.0
CMS2_k127_914943_9 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000008838 149.0
CMS2_k127_990785_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.382e-225 709.0
CMS2_k127_990785_1 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009801 563.0
CMS2_k127_990785_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 529.0
CMS2_k127_990785_3 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 334.0
CMS2_k127_990785_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000004679 199.0
CMS2_k127_990785_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000003555 193.0
CMS2_k127_990785_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000001594 121.0