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Overview

ID MAG00455
Name CMS2_bin.69
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Campylobacterota
Class Campylobacteria
Order Campylobacterales
Family Sulfurimonadaceae
Genus
Species
Assembly information
Completeness (%) 99.93
Contamination (%) 0.99
GC content (%) 40.0
N50 (bp) 29,641
Genome size (bp) 2,494,066

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2292

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1037318_0 K -dependent Na Ca exchanger K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 385.0
CMS2_k127_1037318_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000002908 141.0
CMS2_k127_1037318_2 AF0941-like - - - 0.000000002311 61.0
CMS2_k127_1037318_3 - - - - 0.000001449 50.0
CMS2_k127_1043689_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.303e-282 874.0
CMS2_k127_1043689_1 Single-stranded-DNA-specific exonuclease (RecJ) K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 613.0
CMS2_k127_1043689_10 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003649 275.0
CMS2_k127_1043689_11 Methyltransferase domain K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000103 234.0
CMS2_k127_1043689_12 PFAM Methyltransferase type - - - 0.00000000000000000000000000000000000000000000000000000000000000271 223.0
CMS2_k127_1043689_13 thiamine-phosphate diphosphorylase activity K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000001958 191.0
CMS2_k127_1043689_14 Protein of unknown function (DUF3450) - - - 0.00000000000000000000000000000000000000000000000000002211 196.0
CMS2_k127_1043689_15 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000000000000000000000000000000002141 193.0
CMS2_k127_1043689_16 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000000000000000000009383 178.0
CMS2_k127_1043689_17 SMART GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000005256 168.0
CMS2_k127_1043689_18 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000006535 129.0
CMS2_k127_1043689_19 receptor - - - 0.0000000000000000000000000002274 132.0
CMS2_k127_1043689_2 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 340.0
CMS2_k127_1043689_20 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000002002 117.0
CMS2_k127_1043689_21 Preprotein translocase subunit SecG K03075 - - 0.00000000000000000000000006704 110.0
CMS2_k127_1043689_22 COG0457 FOG TPR repeat - - - 0.00000000000000000000001605 111.0
CMS2_k127_1043689_24 Domain of unknown function (DUF1736) - - - 0.00008953 53.0
CMS2_k127_1043689_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 332.0
CMS2_k127_1043689_4 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 312.0
CMS2_k127_1043689_5 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 305.0
CMS2_k127_1043689_6 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 298.0
CMS2_k127_1043689_7 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004519 289.0
CMS2_k127_1043689_8 Abc transporter K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000119 276.0
CMS2_k127_1043689_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002181 257.0
CMS2_k127_1057657_0 Heat shock 70 kDa protein K04043 - - 0.0 1020.0
CMS2_k127_1057657_1 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 3.804e-304 948.0
CMS2_k127_1057657_10 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 299.0
CMS2_k127_1057657_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001516 256.0
CMS2_k127_1057657_12 PAS fold K03776 - - 0.000000000000000000000000000000000000000000000000000000000000000000004168 236.0
CMS2_k127_1057657_13 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000009165 239.0
CMS2_k127_1057657_14 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000001871 185.0
CMS2_k127_1057657_15 PFAM response regulator receiver K03407,K03413 - 2.7.13.3 0.00000000000000000000000000000000000000000000000002417 181.0
CMS2_k127_1057657_16 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000004719 167.0
CMS2_k127_1057657_17 GGDEF domain K03413 - - 0.000000000000000000000000000000000000000003904 157.0
CMS2_k127_1057657_18 Chemotaxis signal transduction protein K03408 - - 0.000000000000000000000000000000000000003862 163.0
CMS2_k127_1057657_19 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000001172 143.0
CMS2_k127_1057657_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 2.814e-219 698.0
CMS2_k127_1057657_20 PAS fold - - - 0.000000000000000000000000000000000006326 154.0
CMS2_k127_1057657_21 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000004783 129.0
CMS2_k127_1057657_22 - - - - 0.00000000000000000000002277 112.0
CMS2_k127_1057657_23 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000005238 97.0
CMS2_k127_1057657_24 - - - - 0.000000000000000123 91.0
CMS2_k127_1057657_25 COG0835 Chemotaxis signal transduction protein - - - 0.000000000009765 74.0
CMS2_k127_1057657_27 resolvase domain protein - - - 0.000000001026 59.0
CMS2_k127_1057657_3 type II secretion system protein E K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 595.0
CMS2_k127_1057657_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 422.0
CMS2_k127_1057657_5 phosphohydrolase (DHH superfamily) K07097 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 406.0
CMS2_k127_1057657_6 Signal transducing histidine kinase, homodimeric domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 419.0
CMS2_k127_1057657_7 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 386.0
CMS2_k127_1057657_8 NUBPL iron-transfer P-loop NTPase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 334.0
CMS2_k127_1057657_9 Type II secretion system K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 327.0
CMS2_k127_1071388_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 1.103e-261 821.0
CMS2_k127_1071388_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 520.0
CMS2_k127_1071388_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000004238 182.0
CMS2_k127_1071388_11 Putative thioesterase (yiiD_Cterm) - - - 0.0000000000000000000000000000000000000000000000007484 177.0
CMS2_k127_1071388_13 ATPase or kinase K06925 - - 0.00000000000000000000000000000000000001202 148.0
CMS2_k127_1071388_14 S4 domain protein - - - 0.000000000000000000000000000036 118.0
CMS2_k127_1071388_17 ATP synthase, subunit b - - - 0.000001831 55.0
CMS2_k127_1071388_2 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 523.0
CMS2_k127_1071388_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 393.0
CMS2_k127_1071388_4 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 380.0
CMS2_k127_1071388_5 ABC transporter, ATP-binding protein K01990,K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 375.0
CMS2_k127_1071388_6 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 309.0
CMS2_k127_1071388_7 tigr02757 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 306.0
CMS2_k127_1071388_8 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 307.0
CMS2_k127_1071388_9 PFAM Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003274 284.0
CMS2_k127_1103608_0 Type I secretion system ATPase K12541 - - 6.624e-256 807.0
CMS2_k127_1103608_1 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 1.034e-228 719.0
CMS2_k127_1103608_10 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 344.0
CMS2_k127_1103608_11 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 326.0
CMS2_k127_1103608_12 Outer membrane efflux protein K12543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 317.0
CMS2_k127_1103608_13 fumarate reductase, iron-sulfur protein K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001782 283.0
CMS2_k127_1103608_14 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004797 280.0
CMS2_k127_1103608_15 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000006787 262.0
CMS2_k127_1103608_16 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000004039 226.0
CMS2_k127_1103608_17 COGs COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase components K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000001064 215.0
CMS2_k127_1103608_18 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000006545 207.0
CMS2_k127_1103608_19 - K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000005481 192.0
CMS2_k127_1103608_2 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 608.0
CMS2_k127_1103608_20 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.000000000000000000000000000000000000000000000000004903 188.0
CMS2_k127_1103608_21 PFAM Cobinamide kinase cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000003297 183.0
CMS2_k127_1103608_22 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000005939 172.0
CMS2_k127_1103608_23 Outer membrane usher protein K07347 - - 0.00000000000000000000000000000000000002066 166.0
CMS2_k127_1103608_24 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000002664 159.0
CMS2_k127_1103608_25 PFAM Ferric reductase domain protein transmembrane component domain K17247 - - 0.000000000000000000000000000000000225 140.0
CMS2_k127_1103608_26 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000006412 132.0
CMS2_k127_1103608_27 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000308 116.0
CMS2_k127_1103608_28 Protein of unknown function (DUF1566) - - - 0.000000000000000001266 102.0
CMS2_k127_1103608_29 RHS Repeat - - - 0.00000000000000001996 98.0
CMS2_k127_1103608_3 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 507.0
CMS2_k127_1103608_32 cell septum assembly K02343,K02519,K07114,K16147,K20276 - 2.4.99.16,2.7.7.7 0.0000005022 63.0
CMS2_k127_1103608_34 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0002178 55.0
CMS2_k127_1103608_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 498.0
CMS2_k127_1103608_5 type I secretion membrane fusion protein, HlyD family K02022,K12542 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 472.0
CMS2_k127_1103608_6 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 393.0
CMS2_k127_1103608_7 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 387.0
CMS2_k127_1103608_8 phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 385.0
CMS2_k127_1103608_9 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 362.0
CMS2_k127_1110075_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0 1865.0
CMS2_k127_1110075_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.555e-261 811.0
CMS2_k127_1110075_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 512.0
CMS2_k127_1110075_11 Bacterial protein of unknown function (DUF839) K07093 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 456.0
CMS2_k127_1110075_12 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 351.0
CMS2_k127_1110075_13 PFAM tRNA synthetase class II (G H P and S) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 344.0
CMS2_k127_1110075_14 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 337.0
CMS2_k127_1110075_15 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000013 289.0
CMS2_k127_1110075_16 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004106 296.0
CMS2_k127_1110075_17 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000004666 271.0
CMS2_k127_1110075_18 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002274 280.0
CMS2_k127_1110075_19 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000002509 240.0
CMS2_k127_1110075_2 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 2.3e-237 763.0
CMS2_k127_1110075_20 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000001349 239.0
CMS2_k127_1110075_21 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000000000002215 234.0
CMS2_k127_1110075_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004587 222.0
CMS2_k127_1110075_23 protein conserved in bacteria K09804 - - 0.000000000000000000000000000000000000000000000000000000000000001031 223.0
CMS2_k127_1110075_24 chain release factor K15034 - - 0.000000000000000000000000000000000000000000000000000000003855 201.0
CMS2_k127_1110075_25 Pfam Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001149 201.0
CMS2_k127_1110075_26 HD domain - - - 0.00000000000000000000000000000000000000000000000000001072 201.0
CMS2_k127_1110075_27 HD domain - - - 0.00000000000000000000000000000000000000000000000002017 191.0
CMS2_k127_1110075_28 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000007099 179.0
CMS2_k127_1110075_29 homoserine kinase type II (Protein kinase fold) K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000001921 175.0
CMS2_k127_1110075_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 5.889e-216 675.0
CMS2_k127_1110075_30 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000002125 174.0
CMS2_k127_1110075_31 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000005827 169.0
CMS2_k127_1110075_32 COG1393 Arsenate reductase and related K00537 - 1.20.4.1 0.000000000000000000000000000000000000000005076 156.0
CMS2_k127_1110075_33 Bacterial extracellular solute-binding proteins, family 3 - - - 0.0000000000000000000000000000000001098 141.0
CMS2_k127_1110075_34 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000159 132.0
CMS2_k127_1110075_35 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000008998 129.0
CMS2_k127_1110075_36 PDP protein - - - 0.000000000000000000000000000001346 127.0
CMS2_k127_1110075_37 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000004125 120.0
CMS2_k127_1110075_38 - - - - 0.00000000000000000000000000007805 124.0
CMS2_k127_1110075_39 Transcriptional regulator - - - 0.00000000000000000000000000895 115.0
CMS2_k127_1110075_4 Cytosine-specific methyltransferase K00558 - 2.1.1.37 1.174e-197 622.0
CMS2_k127_1110075_40 FixH - - - 0.0000000000000000000000003394 111.0
CMS2_k127_1110075_41 Domain of unknown function DUF302 - - - 0.000000000000000000003162 98.0
CMS2_k127_1110075_42 GDYXXLXY protein - - - 0.00000000000000000001759 98.0
CMS2_k127_1110075_43 Protein of unknown function, DUF255 - - - 0.00000000000000000005459 95.0
CMS2_k127_1110075_44 Nucleotidyltransferase domain K07075 - - 0.000000000000000002234 89.0
CMS2_k127_1110075_45 2'-5' RNA ligase K01975 - 3.1.4.58 0.000000000000000007636 90.0
CMS2_k127_1110075_46 Belongs to the UPF0312 family - - - 0.0000000000000009014 84.0
CMS2_k127_1110075_47 cytochrome c oxidase K00407 - - 0.00000000000001141 75.0
CMS2_k127_1110075_48 Predicted membrane protein (DUF2157) - - - 0.00000000000005009 83.0
CMS2_k127_1110075_49 Flagellar FliJ protein - - - 0.00000000000008479 76.0
CMS2_k127_1110075_5 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 582.0
CMS2_k127_1110075_50 Protein of unknown function DUF86 - - - 0.000000000001275 68.0
CMS2_k127_1110075_51 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00480,K17940,K21272 - 1.14.13.1,1.14.13.182,1.14.13.222 0.000000000006911 67.0
CMS2_k127_1110075_52 PFAM regulatory protein TetR - - - 0.0000000003577 60.0
CMS2_k127_1110075_54 - - - - 0.0002316 45.0
CMS2_k127_1110075_6 COG3893 inactivated superfamily I helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 589.0
CMS2_k127_1110075_7 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 532.0
CMS2_k127_1110075_8 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 515.0
CMS2_k127_1110075_9 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 507.0
CMS2_k127_1195210_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.878e-231 737.0
CMS2_k127_1195210_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 524.0
CMS2_k127_1195210_10 prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 323.0
CMS2_k127_1195210_11 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006917 271.0
CMS2_k127_1195210_12 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000001833 271.0
CMS2_k127_1195210_13 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000003853 254.0
CMS2_k127_1195210_14 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000002296 190.0
CMS2_k127_1195210_15 Ferredoxin K05337 - - 0.00000000000000000000000000000000000000002141 153.0
CMS2_k127_1195210_16 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000004469 108.0
CMS2_k127_1195210_17 - - - - 0.0000000000000000001113 90.0
CMS2_k127_1195210_18 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000006225 93.0
CMS2_k127_1195210_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 522.0
CMS2_k127_1195210_3 peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 504.0
CMS2_k127_1195210_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 471.0
CMS2_k127_1195210_5 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 467.0
CMS2_k127_1195210_6 Histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 462.0
CMS2_k127_1195210_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 417.0
CMS2_k127_1195210_8 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 419.0
CMS2_k127_1195210_9 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 361.0
CMS2_k127_1210025_0 Protein of unknown function (DUF3050) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 389.0
CMS2_k127_1210025_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 362.0
CMS2_k127_1210025_2 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003189 248.0
CMS2_k127_1210025_3 LysE family K06895 - - 0.000000000000000000000000000000000000000000000000000000003733 206.0
CMS2_k127_1210025_4 Ferredoxin - - - 0.00000000000000000000000000000000000000000000004208 170.0
CMS2_k127_1210025_5 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000003764 127.0
CMS2_k127_1210025_6 - - - - 0.000000000000007002 79.0
CMS2_k127_1213851_0 GHKL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 392.0
CMS2_k127_1213851_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 365.0
CMS2_k127_1213851_10 - - - - 0.000000000000000001599 87.0
CMS2_k127_1213851_2 protein conserved in bacteria K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 350.0
CMS2_k127_1213851_3 His Kinase A (phosphoacceptor) domain K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 339.0
CMS2_k127_1213851_4 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 319.0
CMS2_k127_1213851_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000005372 258.0
CMS2_k127_1213851_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000008985 239.0
CMS2_k127_1213851_7 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000001279 187.0
CMS2_k127_1213851_8 DoxX K15977 - - 0.0000000000000000000000001349 113.0
CMS2_k127_1227762_0 Belongs to the UbiD family K03182 - 4.1.1.98 3.393e-275 857.0
CMS2_k127_1227762_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 9.413e-253 791.0
CMS2_k127_1227762_10 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000002552 236.0
CMS2_k127_1227762_11 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000002859 161.0
CMS2_k127_1227762_12 Periplasmic 7TM domain sensor diguanylate cyclase - - - 0.0000000000000000000000000000000000000001086 170.0
CMS2_k127_1227762_13 cell redox homeostasis K12057 - - 0.000000000000000000000000000000003131 133.0
CMS2_k127_1227762_14 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000005811 124.0
CMS2_k127_1227762_15 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000000000000000000005344 113.0
CMS2_k127_1227762_16 - - - - 0.0000000000000000000002307 100.0
CMS2_k127_1227762_17 Protein of unknown function (DUF2089) - - - 0.0000000000000000724 85.0
CMS2_k127_1227762_18 FxsA cytoplasmic membrane protein K01649,K07113 - 2.3.3.13 0.00000000000000009703 86.0
CMS2_k127_1227762_19 cell redox homeostasis - - - 0.000000000001218 74.0
CMS2_k127_1227762_2 argininosuccinate lyase K01755 - 4.3.2.1 2.467e-224 702.0
CMS2_k127_1227762_21 Protein of unknown function (DUF2809) - - - 0.000002576 55.0
CMS2_k127_1227762_3 5'-nucleotidase K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 440.0
CMS2_k127_1227762_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 426.0
CMS2_k127_1227762_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 396.0
CMS2_k127_1227762_6 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 331.0
CMS2_k127_1227762_7 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009491 271.0
CMS2_k127_1227762_8 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001769 268.0
CMS2_k127_1227762_9 redox protein regulator of disulfide bond formation K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005646 245.0
CMS2_k127_1254397_0 penicillin-binding protein K05515 - 3.4.16.4 6.325e-233 735.0
CMS2_k127_1254397_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 498.0
CMS2_k127_1254397_10 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000001198 196.0
CMS2_k127_1254397_11 coproporphyrinogen oxidase activity K00228 GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 0.0000000000000000000000000000000001022 134.0
CMS2_k127_1254397_12 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000001093 141.0
CMS2_k127_1254397_13 Lipopolysaccharide transport periplasmic protein lpta K09774 - - 0.00000000000000000009988 95.0
CMS2_k127_1254397_14 - - - - 0.00000000002938 72.0
CMS2_k127_1254397_15 OstA-like protein - - - 0.0002588 50.0
CMS2_k127_1254397_16 COG3209 Rhs family protein - - - 0.0003504 44.0
CMS2_k127_1254397_2 lytic murein transglycosylase K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 449.0
CMS2_k127_1254397_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 361.0
CMS2_k127_1254397_4 hydrolase, TatD K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 358.0
CMS2_k127_1254397_5 Imidazoleglycerol-phosphate dehydratase K01089,K01693 - 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 288.0
CMS2_k127_1254397_6 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002794 248.0
CMS2_k127_1254397_7 peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000003288 227.0
CMS2_k127_1254397_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000003903 222.0
CMS2_k127_1254397_9 acetyltransferase K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000001221 207.0
CMS2_k127_1266865_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 431.0
CMS2_k127_1266865_1 Mediates zinc uptake. May also transport other divalent cations K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 364.0
CMS2_k127_1266865_10 Alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000008557 149.0
CMS2_k127_1266865_11 -acetyltransferase K06975 - - 0.0000000000000000000000673 101.0
CMS2_k127_1266865_2 CHASE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 376.0
CMS2_k127_1266865_3 PFAM amine oxidase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 310.0
CMS2_k127_1266865_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003359 271.0
CMS2_k127_1266865_5 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004308 284.0
CMS2_k127_1266865_6 Phospholipase/Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002712 258.0
CMS2_k127_1266865_7 dihydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003403 253.0
CMS2_k127_1266865_8 - - - - 0.000000000000000000000000000000000000000000000000001531 184.0
CMS2_k127_1266865_9 - - - - 0.00000000000000000000000000000000000000006407 156.0
CMS2_k127_1298565_0 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000000000000000000004457 208.0
CMS2_k127_1298565_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000005095 81.0
CMS2_k127_1299433_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.059e-301 937.0
CMS2_k127_1299433_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 5.093e-300 934.0
CMS2_k127_1299433_10 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000003801 228.0
CMS2_k127_1299433_11 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000008167 193.0
CMS2_k127_1299433_12 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000002631 108.0
CMS2_k127_1299433_13 - - - - 0.0000000000000000000000001226 121.0
CMS2_k127_1299433_14 Prokaryotic N-terminal methylation motif K02456 - - 0.00000001569 56.0
CMS2_k127_1299433_15 - - - - 0.000000126 56.0
CMS2_k127_1299433_2 Potassium channel protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 515.0
CMS2_k127_1299433_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 483.0
CMS2_k127_1299433_4 Chemotaxis phosphatase CheX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 474.0
CMS2_k127_1299433_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 458.0
CMS2_k127_1299433_6 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 331.0
CMS2_k127_1299433_7 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 289.0
CMS2_k127_1299433_8 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 300.0
CMS2_k127_1299433_9 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001182 280.0
CMS2_k127_1300301_0 fumarate reductase, flavoprotein subunit K00244 - 1.3.5.4 0.0 1065.0
CMS2_k127_1300301_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.295e-280 871.0
CMS2_k127_1300301_10 permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 534.0
CMS2_k127_1300301_11 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 485.0
CMS2_k127_1300301_12 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 408.0
CMS2_k127_1300301_13 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 378.0
CMS2_k127_1300301_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 381.0
CMS2_k127_1300301_15 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 336.0
CMS2_k127_1300301_16 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 325.0
CMS2_k127_1300301_17 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 325.0
CMS2_k127_1300301_18 fumarate reductase K00246 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 317.0
CMS2_k127_1300301_19 short-chain dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
CMS2_k127_1300301_2 Heat shock 70 kDa protein K04043 - - 7.173e-262 820.0
CMS2_k127_1300301_20 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001321 268.0
CMS2_k127_1300301_21 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002093 255.0
CMS2_k127_1300301_22 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007278 252.0
CMS2_k127_1300301_23 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000009256 233.0
CMS2_k127_1300301_24 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000732 196.0
CMS2_k127_1300301_25 Surface antigen - - - 0.00000000000000000000000000000000000000000000000004666 195.0
CMS2_k127_1300301_26 - - - - 0.000000000000000000000000000000000000000000000001879 187.0
CMS2_k127_1300301_27 Transcriptional regulator K03892 - - 0.00000000000000000000000000000000000000000000001822 175.0
CMS2_k127_1300301_28 GtrA-like protein - - - 0.00000000000000000000000000000000000000000000004941 173.0
CMS2_k127_1300301_29 hmm pf01205 - - - 0.00000000000000000000000000000000000000000000324 170.0
CMS2_k127_1300301_3 Malate quinone- oxidoreductase K00116 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.5.4 1.853e-260 809.0
CMS2_k127_1300301_31 Redox-active disulfide protein - - - 0.0000000000000000000000000000006041 124.0
CMS2_k127_1300301_32 - - - - 0.000000000000000000001155 100.0
CMS2_k127_1300301_34 Response regulator receiver - - - 0.00000000000000005691 93.0
CMS2_k127_1300301_36 Uncharacterised protein family (UPF0259) - - - 0.0004618 50.0
CMS2_k127_1300301_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.756e-247 789.0
CMS2_k127_1300301_5 GTP-binding protein - - - 5.77e-230 730.0
CMS2_k127_1300301_6 Dynamin family - - - 1.656e-212 684.0
CMS2_k127_1300301_7 diguanylate cyclase - - - 3.833e-206 658.0
CMS2_k127_1300301_8 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 571.0
CMS2_k127_1300301_9 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 551.0
CMS2_k127_1361340_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 1.624e-241 758.0
CMS2_k127_1361340_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 604.0
CMS2_k127_1361340_10 ATPase (AAA K01714,K12283 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 301.0
CMS2_k127_1361340_11 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000002587 171.0
CMS2_k127_1361340_12 proteins homologs of microcin C7 resistance protein MccF - - - 0.0000000000000000000000000000000000000000003624 164.0
CMS2_k127_1361340_13 - - - - 0.000000000000000000000000000000000000000005498 162.0
CMS2_k127_1361340_14 Cytochrome P460 - - - 0.000000000000000000000000000000000000001559 152.0
CMS2_k127_1361340_16 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000005981 72.0
CMS2_k127_1361340_2 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 498.0
CMS2_k127_1361340_3 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 469.0
CMS2_k127_1361340_4 Type II secretion system K02455,K02653,K12278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 453.0
CMS2_k127_1361340_5 C-terminal domain of metallo-carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 400.0
CMS2_k127_1361340_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 392.0
CMS2_k127_1361340_7 Pilus assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007329 359.0
CMS2_k127_1361340_8 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 308.0
CMS2_k127_1361340_9 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 297.0
CMS2_k127_138975_0 Mitochondrial degradasome RNA helicase subunit C terminal K17675 - 3.6.4.13 3.002e-240 773.0
CMS2_k127_138975_1 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 5.947e-197 623.0
CMS2_k127_138975_10 Glycosyl hydrolase family 3 K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 326.0
CMS2_k127_138975_11 protein involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 327.0
CMS2_k127_138975_12 Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 291.0
CMS2_k127_138975_13 PFAM Glycosyl transferases group 1 K19002 - 2.4.1.337 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002429 284.0
CMS2_k127_138975_14 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003082 271.0
CMS2_k127_138975_15 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008289 255.0
CMS2_k127_138975_16 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000072 243.0
CMS2_k127_138975_17 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001679 243.0
CMS2_k127_138975_18 Protein of unknown function (DUF819) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004061 243.0
CMS2_k127_138975_19 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000000000000000000000001882 229.0
CMS2_k127_138975_2 Fad-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 481.0
CMS2_k127_138975_20 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000005332 226.0
CMS2_k127_138975_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000009482 219.0
CMS2_k127_138975_22 Belongs to the globin family K05916 - 1.14.12.17 0.00000000000000000000000000000000000000000000000000000000000002039 218.0
CMS2_k127_138975_23 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000000000000000000000000000000001078 216.0
CMS2_k127_138975_24 Diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000004559 217.0
CMS2_k127_138975_25 Protein conserved in bacteria K09943 - - 0.000000000000000000000000000000000000000000000000000001303 194.0
CMS2_k127_138975_26 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000677 189.0
CMS2_k127_138975_27 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000002149 176.0
CMS2_k127_138975_28 Protein of unknown function, DUF481 K07283 - - 0.000000000000000000000000000000000000004749 155.0
CMS2_k127_138975_29 RDD family - - - 0.000000000000000000000000000000000000007168 149.0
CMS2_k127_138975_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 450.0
CMS2_k127_138975_30 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000008896 150.0
CMS2_k127_138975_31 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000001719 143.0
CMS2_k127_138975_32 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000001907 142.0
CMS2_k127_138975_33 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000006008 134.0
CMS2_k127_138975_34 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000009236 140.0
CMS2_k127_138975_35 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000003229 132.0
CMS2_k127_138975_36 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000000000003258 108.0
CMS2_k127_138975_37 Conserved region in glutamate synthase - - - 0.00000000000000000000000966 104.0
CMS2_k127_138975_38 methyltransferase - - - 0.00000000000000000000001134 108.0
CMS2_k127_138975_39 cytochrome - - - 0.0000000000000000000007701 100.0
CMS2_k127_138975_4 Major facilitator superfamily K08167 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 458.0
CMS2_k127_138975_40 adenosylhomocysteine nucleosidase activity K01243,K03716 - 3.2.2.9,4.1.99.14 0.0000000000000000002499 99.0
CMS2_k127_138975_42 Domain of unknown function (DUF3817) - - - 0.00000000000000000664 86.0
CMS2_k127_138975_43 Domain of unknown function (DUF309) K09763 - - 0.000000000000000139 83.0
CMS2_k127_138975_5 polyphosphate kinase K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 381.0
CMS2_k127_138975_6 radical SAM domain protein K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 366.0
CMS2_k127_138975_7 COGs COG1033 exporter of the RND superfamily protein K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 362.0
CMS2_k127_138975_8 a g-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 346.0
CMS2_k127_138975_9 Major facilitator superfamily K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 342.0
CMS2_k127_14266_0 Histidine kinase K07641,K07642,K10681,K14980,K18143 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000003205 247.0
CMS2_k127_14266_1 ABC transporter K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000002555 223.0
CMS2_k127_14266_2 Cytochrome P460 - - - 0.00000000000000000000000000000000000000000000000000000002811 201.0
CMS2_k127_14266_3 Transcriptional regulatory protein, C terminal K07775 - - 0.0000000000000000000000000000000000000000724 159.0
CMS2_k127_14266_4 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000172 120.0
CMS2_k127_1433545_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.235e-241 753.0
CMS2_k127_1433545_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 591.0
CMS2_k127_1433545_10 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000004327 163.0
CMS2_k127_1433545_11 TrkA-N domain - - - 0.0000000000000000000000000000000000000004503 157.0
CMS2_k127_1433545_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000005109 149.0
CMS2_k127_1433545_13 that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - 0.000000000000000000000000000000000000009201 159.0
CMS2_k127_1433545_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 405.0
CMS2_k127_1433545_3 potassium channel protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 413.0
CMS2_k127_1433545_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 305.0
CMS2_k127_1433545_5 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 299.0
CMS2_k127_1433545_6 ABC transporter, ATP-binding protein K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001346 243.0
CMS2_k127_1433545_7 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.0000000000000000000000000000000000000000000000000000000006805 217.0
CMS2_k127_1433545_8 Flagellar Assembly Protein A - - - 0.000000000000000000000000000000000000000000000000000000006408 221.0
CMS2_k127_1433545_9 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000000000000000000001542 177.0
CMS2_k127_1730088_0 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 368.0
CMS2_k127_1730088_1 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 321.0
CMS2_k127_1730088_2 COG4886 Leucine-rich repeat (LRR) protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003044 273.0
CMS2_k127_1730088_3 - - - - 0.000000000000000000000000000000000000000000000000000000000002918 218.0
CMS2_k127_1730088_4 CAAX protease self-immunity K07052 - - 0.000000000000000000000000005043 117.0
CMS2_k127_1841780_0 COG0631 Serine threonine protein phosphatase K12132 - 2.7.11.1 4.714e-266 829.0
CMS2_k127_1841780_1 Molecular chaperone. Has ATPase activity K04079 - - 2.21e-255 801.0
CMS2_k127_1841780_10 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 396.0
CMS2_k127_1841780_11 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 360.0
CMS2_k127_1841780_12 component I K01665 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 356.0
CMS2_k127_1841780_13 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 347.0
CMS2_k127_1841780_14 Domain of unknown function (DUF1882) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 301.0
CMS2_k127_1841780_15 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 302.0
CMS2_k127_1841780_16 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 290.0
CMS2_k127_1841780_17 hmm pf04305 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001796 285.0
CMS2_k127_1841780_18 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008385 276.0
CMS2_k127_1841780_19 Peptidase A24 K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000113 259.0
CMS2_k127_1841780_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 4.271e-248 768.0
CMS2_k127_1841780_20 Permease, YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008151 254.0
CMS2_k127_1841780_21 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000001385 248.0
CMS2_k127_1841780_22 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000001904 243.0
CMS2_k127_1841780_23 Belongs to the Fur family K03711 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000003207 220.0
CMS2_k127_1841780_24 MORN repeat variant - - - 0.0000000000000000000000000000000000000000000000000148 198.0
CMS2_k127_1841780_25 Colicin V production protein K03558 - - 0.0000000000000000000000000000000000000000000001313 173.0
CMS2_k127_1841780_27 Omptin family - - - 0.0000000000000000000000000003258 125.0
CMS2_k127_1841780_28 peptide-methionine (S)-S-oxide reductase activity - - - 0.0000000000000000000000000004123 115.0
CMS2_k127_1841780_29 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000001158 116.0
CMS2_k127_1841780_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 6.213e-229 718.0
CMS2_k127_1841780_30 Beta-lactamase superfamily domain - - - 0.00000000000000000000005779 100.0
CMS2_k127_1841780_31 Cell division protein K03591,K03749 - - 0.000000000000000000000566 104.0
CMS2_k127_1841780_4 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 6.108e-210 658.0
CMS2_k127_1841780_5 anthranilate synthase component K01657 - 4.1.3.27 5.815e-208 655.0
CMS2_k127_1841780_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 512.0
CMS2_k127_1841780_7 Formate/nitrite transporter K21993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 473.0
CMS2_k127_1841780_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 440.0
CMS2_k127_1841780_9 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 432.0
CMS2_k127_1947536_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 601.0
CMS2_k127_1947536_1 Abc transporter K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 599.0
CMS2_k127_1947536_10 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 0.0002469 51.0
CMS2_k127_1947536_2 pyruvate ferredoxin oxidoreductase K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 554.0
CMS2_k127_1947536_3 pyruvate ferredoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 326.0
CMS2_k127_1947536_4 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 348.0
CMS2_k127_1947536_5 Hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004624 274.0
CMS2_k127_1947536_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000009374 226.0
CMS2_k127_1947536_7 pyruvate ferredoxin oxidoreductase K00171 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000001374 225.0
CMS2_k127_1947536_8 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000002425 210.0
CMS2_k127_1947536_9 Protein of unknown function (DUF465) K09794 - - 0.000000000000007323 76.0
CMS2_k127_2066130_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1575.0
CMS2_k127_2066130_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114 1.2.7.1 0.0 1544.0
CMS2_k127_2066130_10 Mg chelatase-related protein K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 559.0
CMS2_k127_2066130_11 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 551.0
CMS2_k127_2066130_12 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 532.0
CMS2_k127_2066130_13 Cytochrome c oxidase accessory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 533.0
CMS2_k127_2066130_14 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 523.0
CMS2_k127_2066130_15 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 513.0
CMS2_k127_2066130_16 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 515.0
CMS2_k127_2066130_17 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 505.0
CMS2_k127_2066130_18 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 477.0
CMS2_k127_2066130_19 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 479.0
CMS2_k127_2066130_2 Glycosyl hydrolase family 65 central catalytic domain K01194 - 3.2.1.28 0.0 1437.0
CMS2_k127_2066130_20 PFAM Glycosyl transferase, family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 474.0
CMS2_k127_2066130_21 Belongs to the UPF0324 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 464.0
CMS2_k127_2066130_22 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 466.0
CMS2_k127_2066130_23 - K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 460.0
CMS2_k127_2066130_24 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 449.0
CMS2_k127_2066130_25 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 422.0
CMS2_k127_2066130_26 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 409.0
CMS2_k127_2066130_27 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 359.0
CMS2_k127_2066130_28 Sodium hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 351.0
CMS2_k127_2066130_29 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 340.0
CMS2_k127_2066130_3 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1230.0
CMS2_k127_2066130_30 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 331.0
CMS2_k127_2066130_31 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 314.0
CMS2_k127_2066130_32 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 304.0
CMS2_k127_2066130_33 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000002306 246.0
CMS2_k127_2066130_34 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000172 258.0
CMS2_k127_2066130_35 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008147 253.0
CMS2_k127_2066130_36 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000008162 235.0
CMS2_k127_2066130_37 Flagellar Assembly Protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000002907 243.0
CMS2_k127_2066130_38 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000009821 214.0
CMS2_k127_2066130_39 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000001398 212.0
CMS2_k127_2066130_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1204.0
CMS2_k127_2066130_40 cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000000000000000006668 214.0
CMS2_k127_2066130_41 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000008533 217.0
CMS2_k127_2066130_42 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000004627 210.0
CMS2_k127_2066130_43 Mannosyl-glycoprotein K03796 - - 0.0000000000000000000000000000000000000000000000000000000001582 211.0
CMS2_k127_2066130_44 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000001532 199.0
CMS2_k127_2066130_45 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000002661 206.0
CMS2_k127_2066130_46 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000001102 193.0
CMS2_k127_2066130_47 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000003777 169.0
CMS2_k127_2066130_48 (EAL) domain protein - - - 0.000000000000000000000000000000000000000000007725 180.0
CMS2_k127_2066130_49 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000104 166.0
CMS2_k127_2066130_5 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 9.958e-290 905.0
CMS2_k127_2066130_50 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000834 161.0
CMS2_k127_2066130_51 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000001661 143.0
CMS2_k127_2066130_52 - - - - 0.00000000000000000000000000000000131 141.0
CMS2_k127_2066130_53 proton-transporting ATP synthase activity, rotational mechanism K02115 - - 0.0000000000000000000000000000002565 134.0
CMS2_k127_2066130_54 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000001885 120.0
CMS2_k127_2066130_55 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000002886 118.0
CMS2_k127_2066130_56 Protein of unknown function, DUF255 - - - 0.0000000000000000000000003388 109.0
CMS2_k127_2066130_57 Thioesterase-like superfamily - - - 0.00000000000000000000003286 106.0
CMS2_k127_2066130_58 negative regulation of translational initiation - - - 0.000000000000122 77.0
CMS2_k127_2066130_59 CAAX protease self-immunity K07052 - - 0.0000000000006439 77.0
CMS2_k127_2066130_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 7.114e-255 792.0
CMS2_k127_2066130_60 protein N-acetylglucosaminyltransferase activity - - - 0.000000000002917 80.0
CMS2_k127_2066130_61 epsilon subunit K02114 - - 0.00000000002657 69.0
CMS2_k127_2066130_62 - - - - 0.0000000001623 62.0
CMS2_k127_2066130_63 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000006555 66.0
CMS2_k127_2066130_66 Belongs to the bacterial histone-like protein family - - - 0.000001141 60.0
CMS2_k127_2066130_67 BON domain - - - 0.000002668 59.0
CMS2_k127_2066130_68 F0F1-ATPase subunit K02116 - - 0.000002831 53.0
CMS2_k127_2066130_69 Voltage gated chloride channel K03281 - - 0.000006107 54.0
CMS2_k127_2066130_7 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.482e-207 655.0
CMS2_k127_2066130_70 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.000006504 51.0
CMS2_k127_2066130_71 LysM domain - - - 0.00007285 51.0
CMS2_k127_2066130_8 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 616.0
CMS2_k127_2066130_9 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 579.0
CMS2_k127_2076507_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.752e-273 845.0
CMS2_k127_2076507_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.045e-262 812.0
CMS2_k127_2076507_10 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002113 266.0
CMS2_k127_2076507_11 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007314 266.0
CMS2_k127_2076507_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000008971 240.0
CMS2_k127_2076507_13 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K18284 - 3.2.2.30,3.2.2.9 0.0000000000000000000000000000000000000000000000000000000000000000005609 231.0
CMS2_k127_2076507_14 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000001772 216.0
CMS2_k127_2076507_15 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000124 204.0
CMS2_k127_2076507_16 MotA TolQ ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000003617 195.0
CMS2_k127_2076507_17 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000001102 182.0
CMS2_k127_2076507_18 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000001943 183.0
CMS2_k127_2076507_19 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000002731 177.0
CMS2_k127_2076507_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 488.0
CMS2_k127_2076507_20 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000009806 177.0
CMS2_k127_2076507_21 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000000000004449 166.0
CMS2_k127_2076507_22 - - - - 0.000000000000000000000000000000000000000001463 157.0
CMS2_k127_2076507_23 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000001383 156.0
CMS2_k127_2076507_24 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001063 153.0
CMS2_k127_2076507_25 transport protein K03559 - - 0.0000000000000000000000000000000000001558 145.0
CMS2_k127_2076507_26 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000002625 140.0
CMS2_k127_2076507_27 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000001158 132.0
CMS2_k127_2076507_28 Belongs to the ATPase B chain family K02109 - - 0.000000000000000000000000000001788 125.0
CMS2_k127_2076507_29 Protein of unknown function, DUF255 - - - 0.000000000000000000003568 98.0
CMS2_k127_2076507_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 477.0
CMS2_k127_2076507_30 TonB C terminal K03832 - - 0.0000003058 61.0
CMS2_k127_2076507_4 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 476.0
CMS2_k127_2076507_5 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 430.0
CMS2_k127_2076507_6 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 428.0
CMS2_k127_2076507_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 387.0
CMS2_k127_2076507_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 377.0
CMS2_k127_2076507_9 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 352.0
CMS2_k127_2084177_0 PFAM CheW domain protein - - - 8.522e-267 847.0
CMS2_k127_2084177_1 cofactor biosynthesis protein NifE K02587 - - 5.061e-253 785.0
CMS2_k127_2084177_10 Nitrogen fixation protein NifW K02595 - - 0.0000000000000000000000000000000000000000000000000001555 188.0
CMS2_k127_2084177_11 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000001227 182.0
CMS2_k127_2084177_12 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000003165 176.0
CMS2_k127_2084177_13 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000002402 170.0
CMS2_k127_2084177_14 NifZ domain K02597 - - 0.00000000000000000000000000000000000000004277 155.0
CMS2_k127_2084177_15 nitrogen fixation protein FixT K02593 - - 0.00000000000000000001123 94.0
CMS2_k127_2084177_2 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 8.577e-216 683.0
CMS2_k127_2084177_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 3.83e-213 668.0
CMS2_k127_2084177_4 Belongs to the NifD NifK NifE NifN family K02592 - - 2.281e-211 664.0
CMS2_k127_2084177_5 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 529.0
CMS2_k127_2084177_6 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 489.0
CMS2_k127_2084177_7 Low-potential electron donor to a number of redox enzymes K03839 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003994 270.0
CMS2_k127_2084177_8 Nitrogen fixation protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001425 226.0
CMS2_k127_2084177_9 Dinitrogenase iron-molybdenum cofactor biosynthesis protein K02596 - - 0.00000000000000000000000000000000000000000000000000000000001828 209.0
CMS2_k127_2098177_0 transcriptional regulator, Crp K01420 - - 0.0000000000000000005763 89.0
CMS2_k127_2139543_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 482.0
CMS2_k127_2139543_1 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 361.0
CMS2_k127_2139543_10 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000002236 112.0
CMS2_k127_2139543_11 Oxygen tolerance - - - 0.0000003933 63.0
CMS2_k127_2139543_12 - K06950 - - 0.0002427 46.0
CMS2_k127_2139543_2 chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 307.0
CMS2_k127_2139543_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001129 289.0
CMS2_k127_2139543_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000003751 205.0
CMS2_k127_2139543_5 sensor protein - - - 0.00000000000000000000000000000000000000000000000000000006111 199.0
CMS2_k127_2139543_6 cyclic nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000001009 218.0
CMS2_k127_2139543_7 - - - - 0.000000000000000000000000000000000000000000000000000001018 214.0
CMS2_k127_2139543_8 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000003374 153.0
CMS2_k127_2139543_9 - - - - 0.000000000000000000000000000000001949 133.0
CMS2_k127_21898_0 Belongs to the succinate malate CoA ligase beta subunit family K15231 - 2.3.3.8 5.405e-252 781.0
CMS2_k127_21898_1 ATP citrate synthase K15230 - 2.3.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 453.0
CMS2_k127_21898_2 Anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 285.0
CMS2_k127_21898_3 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008701 251.0
CMS2_k127_2197756_0 Bacterial periplasmic substrate-binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 324.0
CMS2_k127_2197756_1 PFAM Ig domain protein group 2 domain protein - - - 0.000000000000000000000000000000000000000000000006505 188.0
CMS2_k127_2197756_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000003232 158.0
CMS2_k127_2197756_3 Protein of unknown function (DUF1566) - - - 0.000000000000000001842 94.0
CMS2_k127_2197756_4 PFAM Plasmid maintenance system killer K07334 - - 0.0000005113 51.0
CMS2_k127_2231412_0 Peptidase family M41 - - - 8.56e-259 820.0
CMS2_k127_2231412_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 525.0
CMS2_k127_2231412_2 Sodium calcium exchanger membrane K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 393.0
CMS2_k127_2231412_3 - K12065 - - 0.000000000000000000000000000000000000000000000000000000000000000003892 241.0
CMS2_k127_2231412_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000004281 193.0
CMS2_k127_2231412_5 FMN binding - - - 0.000000000000000000000000000003321 126.0
CMS2_k127_2231412_6 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000002025 60.0
CMS2_k127_2231412_7 - - - - 0.00000001712 61.0
CMS2_k127_2231412_8 - - - - 0.000003319 56.0
CMS2_k127_2260153_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 434.0
CMS2_k127_2260153_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 308.0
CMS2_k127_2260153_2 Serine hydrolase K07002 - - 0.0000000000000000001734 89.0
CMS2_k127_2264556_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1007.0
CMS2_k127_2264556_1 TonB-dependent copper receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 522.0
CMS2_k127_2264556_10 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000009252 159.0
CMS2_k127_2264556_11 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000001204 106.0
CMS2_k127_2264556_2 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 362.0
CMS2_k127_2264556_3 PFAM Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 326.0
CMS2_k127_2264556_4 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007665 288.0
CMS2_k127_2264556_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001582 256.0
CMS2_k127_2264556_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000003681 190.0
CMS2_k127_2264556_7 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000004238 182.0
CMS2_k127_2264556_8 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000000004759 178.0
CMS2_k127_2264556_9 Protein of unknown function (DUF3450) - - - 0.000000000000000000000000000000000000000000000433 175.0
CMS2_k127_229342_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.44e-208 653.0
CMS2_k127_229342_1 PFAM major facilitator superfamily MFS_1 K02429 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 385.0
CMS2_k127_229342_2 - - - - 0.00000000000000000000000000000000000000941 149.0
CMS2_k127_2375070_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.518e-288 896.0
CMS2_k127_2375070_1 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 613.0
CMS2_k127_2375070_2 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 529.0
CMS2_k127_2375070_3 flagellar motor switch protein K02410 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 506.0
CMS2_k127_2375070_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 428.0
CMS2_k127_2375070_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 356.0
CMS2_k127_2375070_6 HAD-superfamily hydrolase, subfamily IIA K02566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 291.0
CMS2_k127_2375070_7 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000005586 241.0
CMS2_k127_2375070_8 flagellar assembly protein FliH K02411 - - 0.00000000000000000000000000000004435 136.0
CMS2_k127_238328_0 cytochrome c - - - 6.669e-269 837.0
CMS2_k127_238328_1 ATP-dependent DNA helicase K03655 - 3.6.4.12 5.138e-195 625.0
CMS2_k127_238328_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 573.0
CMS2_k127_238328_3 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 447.0
CMS2_k127_238328_4 Hep Hag repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004521 267.0
CMS2_k127_238328_5 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.0000000000000000000000000000000000000000000000000000000001578 208.0
CMS2_k127_238328_6 Prepilin-type N-terminal cleavage methylation domain - - - 0.00000000000000000000000000000000000000000000006709 181.0
CMS2_k127_238328_7 - - - - 0.00000000000000000000000000001305 123.0
CMS2_k127_238328_8 Domain of unknown function DUF302 - - - 0.0000000000000000000003795 101.0
CMS2_k127_238328_9 type IV pilus modification protein PilV - - - 0.0000000000000000001349 97.0
CMS2_k127_2456459_0 Belongs to the ClpA ClpB family K03694,K03695 - - 0.0 1241.0
CMS2_k127_2456459_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1198.0
CMS2_k127_2456459_10 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 419.0
CMS2_k127_2456459_11 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 419.0
CMS2_k127_2456459_12 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 413.0
CMS2_k127_2456459_13 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 402.0
CMS2_k127_2456459_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 404.0
CMS2_k127_2456459_15 Co-chaperone-curved DNA binding protein A K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009985 379.0
CMS2_k127_2456459_16 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 350.0
CMS2_k127_2456459_17 Epimerase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 299.0
CMS2_k127_2456459_18 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001132 298.0
CMS2_k127_2456459_19 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003423 276.0
CMS2_k127_2456459_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.614e-269 835.0
CMS2_k127_2456459_20 Jag_N K06346 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000135 261.0
CMS2_k127_2456459_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008789 253.0
CMS2_k127_2456459_22 Lipocalin-like domain K03098 GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033554,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000001443 228.0
CMS2_k127_2456459_23 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000000000002625 229.0
CMS2_k127_2456459_24 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000008778 247.0
CMS2_k127_2456459_25 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000001205 227.0
CMS2_k127_2456459_26 - - - - 0.0000000000000000000000000000000000000000000000000000002424 201.0
CMS2_k127_2456459_27 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000002253 195.0
CMS2_k127_2456459_28 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000004553 180.0
CMS2_k127_2456459_29 Transcriptional regulator K13640 - - 0.00000000000000000000000000000000000000000000002499 172.0
CMS2_k127_2456459_3 PFAM Archaeal ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 578.0
CMS2_k127_2456459_30 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000001166 171.0
CMS2_k127_2456459_31 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000001275 168.0
CMS2_k127_2456459_33 glucose galactose transporter K02429 - - 0.00000000000000000000000000000000000000001696 154.0
CMS2_k127_2456459_34 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000000000000000002287 149.0
CMS2_k127_2456459_35 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000000033 139.0
CMS2_k127_2456459_36 Ankyrin repeat - - - 0.00000000000000000000000000000001258 133.0
CMS2_k127_2456459_37 Could be involved in insertion of integral membrane proteins into the membrane - - - 0.000000000000000000000000000001635 123.0
CMS2_k127_2456459_38 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000233 124.0
CMS2_k127_2456459_39 - - - - 0.00000000000000000000000000006991 119.0
CMS2_k127_2456459_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 545.0
CMS2_k127_2456459_40 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000001212 107.0
CMS2_k127_2456459_41 MTH538 TIR-like domain (DUF1863) - - - 0.0000000000000000000007388 100.0
CMS2_k127_2456459_42 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000001453 94.0
CMS2_k127_2456459_43 thiamine biosynthesis protein ThiS K03154 - - 0.000000000000000002679 85.0
CMS2_k127_2456459_44 - - - - 0.0000000000000004942 85.0
CMS2_k127_2456459_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 535.0
CMS2_k127_2456459_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 508.0
CMS2_k127_2456459_7 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 484.0
CMS2_k127_2456459_8 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 459.0
CMS2_k127_2456459_9 Ecdysteroid kinase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 430.0
CMS2_k127_2492069_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 606.0
CMS2_k127_2492069_1 Sulfite dehydrogenase (Cytochrome) subunit SorA apoprotein K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 586.0
CMS2_k127_2492069_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 358.0
CMS2_k127_2492069_11 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 332.0
CMS2_k127_2492069_12 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 314.0
CMS2_k127_2492069_13 Belongs to the sigma-70 factor family K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 299.0
CMS2_k127_2492069_14 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 291.0
CMS2_k127_2492069_15 flagellar motor switch protein K02417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 288.0
CMS2_k127_2492069_16 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000002699 261.0
CMS2_k127_2492069_17 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000311 234.0
CMS2_k127_2492069_18 involved in DNA uptake K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000002943 234.0
CMS2_k127_2492069_19 DNA replication regulator - - - 0.000000000000000000000000000000000000000000000000000000000000005267 220.0
CMS2_k127_2492069_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 534.0
CMS2_k127_2492069_20 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000000000000000003641 218.0
CMS2_k127_2492069_21 Histidine kinase K13040 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000502 196.0
CMS2_k127_2492069_22 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000006157 173.0
CMS2_k127_2492069_23 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000004232 159.0
CMS2_k127_2492069_24 cytochrome C oxidoreductase subunit B - - - 0.000000000000000000000000000000000000005731 151.0
CMS2_k127_2492069_25 Rhodanese Homology Domain - - - 0.000000000000000000000000001158 117.0
CMS2_k127_2492069_26 protein ubiquitination K15502,K15503 - - 0.000000000000000000000000003834 126.0
CMS2_k127_2492069_27 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000000003887 100.0
CMS2_k127_2492069_28 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000001546 103.0
CMS2_k127_2492069_29 - - - - 0.0000000000000001988 83.0
CMS2_k127_2492069_3 flagellar motor switch protein K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 522.0
CMS2_k127_2492069_30 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000001005 55.0
CMS2_k127_2492069_4 flagellar biosynthesis K02404 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 516.0
CMS2_k127_2492069_5 dihydropteroate synthase K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 468.0
CMS2_k127_2492069_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 445.0
CMS2_k127_2492069_7 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 426.0
CMS2_k127_2492069_8 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 416.0
CMS2_k127_2492069_9 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 399.0
CMS2_k127_262077_0 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 564.0
CMS2_k127_262077_1 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000001041 229.0
CMS2_k127_26230_0 Nitrogenase protein alpha chain K02586 - 1.18.6.1 4.004e-295 909.0
CMS2_k127_26230_1 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 6.585e-294 907.0
CMS2_k127_26230_10 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003437 265.0
CMS2_k127_26230_11 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000006445 210.0
CMS2_k127_26230_12 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000002418 198.0
CMS2_k127_26230_13 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000007193 194.0
CMS2_k127_26230_15 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000007141 188.0
CMS2_k127_26230_16 COGs COG3864 conserved - - - 0.00000000000000000000000000000000000000000000003021 173.0
CMS2_k127_26230_17 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000006497 168.0
CMS2_k127_26230_18 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000008081 163.0
CMS2_k127_26230_19 Dinitrogenase iron-molybdenum cofactor biosynthesis protein K02596 - - 0.00000000000000000000000000000000000000056 151.0
CMS2_k127_26230_2 Nitrogenase cofactor biosynthesis protein NifB K02585 - - 2.181e-264 818.0
CMS2_k127_26230_20 - - - - 0.000000000000000000000000000000000000004002 152.0
CMS2_k127_26230_21 - - - - 0.0000000000000000000000000000000000768 134.0
CMS2_k127_26230_22 - - - - 0.000000000000000000000000000000002958 131.0
CMS2_k127_26230_24 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000001427 122.0
CMS2_k127_26230_27 Rop-like - - - 0.0000000000007826 70.0
CMS2_k127_26230_28 nucleotide-binding oligomerization domain containing 1 signaling pathway K08846 GO:0000165,GO:0000187,GO:0001775,GO:0001817,GO:0001819,GO:0001932,GO:0001934,GO:0001959,GO:0001961,GO:0002020,GO:0002218,GO:0002221,GO:0002224,GO:0002237,GO:0002250,GO:0002253,GO:0002376,GO:0002429,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0002697,GO:0002699,GO:0002753,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0002791,GO:0002793,GO:0002819,GO:0002821,GO:0002822,GO:0002824,GO:0002825,GO:0002827,GO:0002831,GO:0002833,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006508,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007154,GO:0007165,GO:0007166,GO:0007249,GO:0007254,GO:0008150,GO:0008152,GO:0008219,GO:0008283,GO:0008284,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010506,GO:0010508,GO:0010556,GO:0010557,GO:0010562,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010799,GO:0010800,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0014070,GO:0016239,GO:0016241,GO:0016301,GO:0016310,GO:0016485,GO:0016740,GO:0016772,GO:0016773,GO:0019219,GO:0019220,GO:0019221,GO:0019222,GO:0019538,GO:0019899,GO:0019904,GO:0022407,GO:0022409,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0030155,GO:0030162,GO:0030274,GO:0030522,GO:0031098,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031347,GO:0031349,GO:0031396,GO:0031398,GO:0031399,GO:0031401,GO:0031638,GO:0031663,GO:0031982,GO:0032092,GO:0032101,GO:0032103,GO:0032147,GO:0032268,GO:0032270,GO:0032479,GO:0032481,GO:0032494,GO:0032495,GO:0032496,GO:0032642,GO:0032647,GO:0032648,GO:0032649,GO:0032651,GO:0032652,GO:0032655,GO:0032663,GO:0032675,GO:0032680,GO:0032722,GO:0032727,GO:0032728,GO:0032729,GO:0032731,GO:0032732,GO:0032735,GO:0032743,GO:0032755,GO:0032760,GO:0032872,GO:0032874,GO:0032879,GO:0032880,GO:0032943,GO:0032944,GO:0032946,GO:0032991,GO:0033083,GO:0033091,GO:0033135,GO:0033138,GO:0033554,GO:0033674,GO:0033993,GO:0034097,GO:0034134,GO:0034142,GO:0035556,GO:0035690,GO:0035872,GO:0036211,GO:0042098,GO:0042102,GO:0042110,GO:0042127,GO:0042129,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042742,GO:0042802,GO:0042803,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043122,GO:0043123,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043330,GO:0043331,GO:0043370,GO:0043372,GO:0043393,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043549,GO:0043900,GO:0043902,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045321,GO:0045580,GO:0045582,GO:0045595,GO:0045597,GO:0045619,GO:0045621,GO:0045622,GO:0045624,GO:0045625,GO:0045627,GO:0045785,GO:0045859,GO:0045860,GO:0045862,GO:0045893,GO:0045935,GO:0045937,GO:0045944,GO:0046328,GO:0046330,GO:0046634,GO:0046635,GO:0046637,GO:0046638,GO:0046640,GO:0046641,GO:0046649,GO:0046651,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050670,GO:0050671,GO:0050700,GO:0050704,GO:0050706,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050716,GO:0050718,GO:0050730,GO:0050731,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050830,GO:0050851,GO:0050852,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051090,GO:0051091,GO:0051092,GO:0051094,GO:0051098,GO:0051099,GO:0051171,GO:0051173,GO:0051174,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051249,GO:0051251,GO:0051252,GO:0051254,GO:0051336,GO:0051338,GO:0051345,GO:0051347,GO:0051403,GO:0051604,GO:0051704,GO:0051707,GO:0051716,GO:0052547,GO:0052548,GO:0060255,GO:0060548,GO:0060759,GO:0060760,GO:0065007,GO:0065009,GO:0070201,GO:0070302,GO:0070304,GO:0070372,GO:0070374,GO:0070391,GO:0070423,GO:0070427,GO:0070431,GO:0070498,GO:0070555,GO:0070661,GO:0070663,GO:0070665,GO:0070671,GO:0070673,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071223,GO:0071224,GO:0071225,GO:0071310,GO:0071345,GO:0071347,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071900,GO:0071902,GO:0080090,GO:0080134,GO:0080135,GO:0089720,GO:0090087,GO:0097202,GO:0098542,GO:0140096,GO:1901564,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902105,GO:1902107,GO:1902531,GO:1902533,GO:1902680,GO:1903037,GO:1903039,GO:1903320,GO:1903322,GO:1903506,GO:1903508,GO:1903530,GO:1903532,GO:1903555,GO:1903557,GO:1903706,GO:1903708,GO:1904415,GO:1904417,GO:1904951,GO:2000026,GO:2000112,GO:2000116,GO:2000514,GO:2000516,GO:2001056,GO:2001141 2.7.11.1 0.000000001489 70.0
CMS2_k127_26230_3 Cysteine desulfurase K04487 - 2.8.1.7 7.176e-208 651.0
CMS2_k127_26230_30 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000003503 58.0
CMS2_k127_26230_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.125e-202 636.0
CMS2_k127_26230_5 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 540.0
CMS2_k127_26230_6 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 510.0
CMS2_k127_26230_7 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 484.0
CMS2_k127_26230_8 SIR2-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 456.0
CMS2_k127_26230_9 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 334.0
CMS2_k127_2704035_0 Uncharacterized ACR, YdiU/UPF0061 family - - - 4.578e-284 880.0
CMS2_k127_2704035_2 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000001939 232.0
CMS2_k127_2704035_3 Protein of unknown function (DUF2569) - - - 0.0000000000000000000000000000000000000000000000000001334 190.0
CMS2_k127_2704035_4 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000009338 198.0
CMS2_k127_2704035_5 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000001486 193.0
CMS2_k127_2704035_6 - - - - 0.000000000000000000000006545 106.0
CMS2_k127_2704035_7 transcriptional regulator - - - 0.00000000000000000000003905 106.0
CMS2_k127_2704035_8 - - - - 0.0002544 44.0
CMS2_k127_3061685_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 467.0
CMS2_k127_3061685_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006735 232.0
CMS2_k127_3061685_2 PFAM Thioredoxin domain K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000005436 172.0
CMS2_k127_3061685_3 YceI-like domain - - - 0.000000000000000000000000000007258 125.0
CMS2_k127_3073483_0 protein conserved in bacteria - - - 0.000008741 49.0
CMS2_k127_3129774_0 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 - - 4.462e-239 745.0
CMS2_k127_3129774_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 495.0
CMS2_k127_3129774_10 thioesterase K02614 - - 0.00000000000000000000000000006585 121.0
CMS2_k127_3129774_11 VRR-NUC domain - - - 0.000000000000000000000000001248 115.0
CMS2_k127_3129774_12 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000002028 106.0
CMS2_k127_3129774_2 DbpA RNA binding domain K05591 GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 422.0
CMS2_k127_3129774_3 pyridine nucleotide-disulfide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 388.0
CMS2_k127_3129774_4 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 385.0
CMS2_k127_3129774_5 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 365.0
CMS2_k127_3129774_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 297.0
CMS2_k127_3129774_7 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 287.0
CMS2_k127_3129774_8 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002244 271.0
CMS2_k127_3129774_9 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000002797 220.0
CMS2_k127_3172611_0 threonine synthase K01733 - 4.2.3.1 9.32e-241 751.0
CMS2_k127_3172611_1 Highly conserved protein containing a thioredoxin domain K06888 - - 2.836e-221 703.0
CMS2_k127_3172611_10 cheY-homologous receiver domain - - - 0.0000000000000000000000000001634 126.0
CMS2_k127_3172611_11 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000001142 107.0
CMS2_k127_3172611_12 - - - - 0.000000000000000001188 89.0
CMS2_k127_3172611_13 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.00000000000001089 73.0
CMS2_k127_3172611_14 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000006101 76.0
CMS2_k127_3172611_2 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 530.0
CMS2_k127_3172611_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 362.0
CMS2_k127_3172611_4 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 349.0
CMS2_k127_3172611_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 287.0
CMS2_k127_3172611_6 - - - - 0.000000000000000000000000000000000000000000000003497 186.0
CMS2_k127_3172611_7 Protein of unknown function (DUF3299) - - - 0.000000000000000000000000000000003439 135.0
CMS2_k127_3172611_8 - - - - 0.000000000000000000000000000000009472 135.0
CMS2_k127_3172611_9 Belongs to the ArsC family - - - 0.000000000000000000000000000009522 123.0
CMS2_k127_325787_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 3.245e-207 655.0
CMS2_k127_325787_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 403.0
CMS2_k127_325787_2 cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 394.0
CMS2_k127_325787_3 membrane K15270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 384.0
CMS2_k127_325787_4 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 349.0
CMS2_k127_325787_5 Membrane-bound lytic murein transglycosylase C K08306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 335.0
CMS2_k127_325787_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000001071 258.0
CMS2_k127_325787_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000001354 191.0
CMS2_k127_325787_8 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000000000000000000002014 191.0
CMS2_k127_325787_9 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000006602 186.0
CMS2_k127_3285094_0 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 1.486e-251 782.0
CMS2_k127_3285094_1 Diguanylate cyclase K20964 - 3.1.4.52 6.749e-244 779.0
CMS2_k127_3285094_10 Methyltransferase domain K00563 - 2.1.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 385.0
CMS2_k127_3285094_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 359.0
CMS2_k127_3285094_12 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 358.0
CMS2_k127_3285094_13 RNase H K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 348.0
CMS2_k127_3285094_14 leucine binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 344.0
CMS2_k127_3285094_15 Specifically methylates the adenine in position 1618 of 23S rRNA K06970 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052907,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 342.0
CMS2_k127_3285094_16 Pseudouridine synthase K06175 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 312.0
CMS2_k127_3285094_17 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 297.0
CMS2_k127_3285094_18 PFAM Ferredoxin thioredoxin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 292.0
CMS2_k127_3285094_19 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 293.0
CMS2_k127_3285094_2 cyclic-guanylate-specific phosphodiesterase activity K21023 - 2.7.7.65 2.055e-229 725.0
CMS2_k127_3285094_20 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 289.0
CMS2_k127_3285094_21 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002488 267.0
CMS2_k127_3285094_22 phenylacetate-CoA ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001376 262.0
CMS2_k127_3285094_23 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000002852 256.0
CMS2_k127_3285094_24 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007025 259.0
CMS2_k127_3285094_25 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008697 257.0
CMS2_k127_3285094_26 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.000000000000000000000000000000000000000000000000000001797 194.0
CMS2_k127_3285094_27 SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000231 197.0
CMS2_k127_3285094_28 Peptidase M48 K03799 - - 0.00000000000000000000000000000000000000000000000000001518 200.0
CMS2_k127_3285094_29 Haem-binding domain - - - 0.0000000000000000000000000000000000000000000000000001305 189.0
CMS2_k127_3285094_3 STAS domain K03321 - - 5.636e-227 715.0
CMS2_k127_3285094_30 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000001801 172.0
CMS2_k127_3285094_31 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000004327 163.0
CMS2_k127_3285094_32 hmm pf04314 K09796 - - 0.0000000000000000000000000000000000000000008712 161.0
CMS2_k127_3285094_33 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000003857 150.0
CMS2_k127_3285094_34 PFAM DTW domain containing protein - - - 0.00000000000000000000000000000000003705 139.0
CMS2_k127_3285094_35 Thioredoxin K03671 - - 0.00000000000000000000000000000005323 128.0
CMS2_k127_3285094_36 Pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000008285 130.0
CMS2_k127_3285094_37 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000576 125.0
CMS2_k127_3285094_38 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000004073 113.0
CMS2_k127_3285094_39 and calponin homology - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005938,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0032153,GO:0032154,GO:0032155,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944,GO:0098590,GO:0099568 - 0.000000000000000004604 91.0
CMS2_k127_3285094_40 Protein of unknown function (DUF2905) - - - 0.00000000000000009004 81.0
CMS2_k127_3285094_41 PepSY-associated TM region - - - 0.0000000000000005843 85.0
CMS2_k127_3285094_42 - - - - 0.00000000000000178 83.0
CMS2_k127_3285094_44 - - - - 0.0001259 48.0
CMS2_k127_3285094_5 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 454.0
CMS2_k127_3285094_6 Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA K03212 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.189 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 441.0
CMS2_k127_3285094_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 447.0
CMS2_k127_3285094_8 PFAM Bacterial transcription activator, effector binding domain K13652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 416.0
CMS2_k127_3285094_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 387.0
CMS2_k127_3290183_0 DNA polymerase K02337 - 2.7.7.7 0.0 1817.0
CMS2_k127_3290183_1 acetolactate synthase K01652 - 2.2.1.6 1.219e-296 918.0
CMS2_k127_3290183_10 - - - - 0.00000000000000000000000001092 111.0
CMS2_k127_3290183_11 Protein of unknown function (DUF2892) - - - 0.0000000000000001471 81.0
CMS2_k127_3290183_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 361.0
CMS2_k127_3290183_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 346.0
CMS2_k127_3290183_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 283.0
CMS2_k127_3290183_5 acetolactate synthase K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000003262 240.0
CMS2_k127_3290183_6 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000001618 199.0
CMS2_k127_3290183_7 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000706 180.0
CMS2_k127_3290183_8 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000006923 144.0
CMS2_k127_3290183_9 Protein required for attachment to host cells - - - 0.00000000000000000000000000000009042 129.0
CMS2_k127_333194_0 hydrogenase (NiFe) small subunit HydA K05927 - 1.12.5.1 0.0 1054.0
CMS2_k127_333194_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 1.34e-296 917.0
CMS2_k127_333194_10 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000000000004911 194.0
CMS2_k127_333194_11 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000000008784 147.0
CMS2_k127_333194_12 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000007913 140.0
CMS2_k127_333194_13 Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000833 147.0
CMS2_k127_333194_14 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000002139 136.0
CMS2_k127_333194_15 Bacterial protein of unknown function (YtfJ_HI0045) K07109 - - 0.0000000000000000000000000000001958 130.0
CMS2_k127_333194_16 hydrogenase assembly chaperone HypC K04653 - - 0.0000000000000000000000000001406 116.0
CMS2_k127_333194_17 Domain of unknown function DUF21 - - - 0.000000000000000000000004461 105.0
CMS2_k127_333194_19 Hpt sensor hybrid histidine kinase - - - 0.0000000000002431 74.0
CMS2_k127_333194_2 Belongs to the HypD family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 533.0
CMS2_k127_333194_20 beta-lactamase activity K07126,K15474 - - 0.000000007412 60.0
CMS2_k127_333194_21 - - - - 0.000004526 56.0
CMS2_k127_333194_22 ATPase activity K02013,K05776 - 3.6.3.34 0.000004848 55.0
CMS2_k127_333194_3 Hpt sensor hybrid histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 544.0
CMS2_k127_333194_4 hydrogenase expression formation protein K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 419.0
CMS2_k127_333194_5 Hydrogenase K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 364.0
CMS2_k127_333194_6 Diguanylate cyclase (GGDEF domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 357.0
CMS2_k127_333194_7 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 311.0
CMS2_k127_333194_8 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 293.0
CMS2_k127_333194_9 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000999 222.0
CMS2_k127_3353308_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000007868 217.0
CMS2_k127_3353308_1 - - - - 0.000000000000000000000000000000000000000000000000000000002205 208.0
CMS2_k127_3353308_2 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000004853 185.0
CMS2_k127_3353308_3 - - - - 0.000000000000000000000000000000000000000000000002821 179.0
CMS2_k127_3406431_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1303.0
CMS2_k127_3406431_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 9.683e-277 853.0
CMS2_k127_3406431_10 - - - - 0.000000000000000000000000229 112.0
CMS2_k127_3406431_11 signal sequence binding - - - 0.00000000001014 72.0
CMS2_k127_3406431_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 5.298e-220 686.0
CMS2_k127_3406431_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008474 543.0
CMS2_k127_3406431_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 525.0
CMS2_k127_3406431_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 312.0
CMS2_k127_3406431_6 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 291.0
CMS2_k127_3406431_7 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001353 308.0
CMS2_k127_3406431_8 ADP-ribose pyrophosphatase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000995 194.0
CMS2_k127_3406431_9 Heavy-metal-associated domain - - - 0.000000000000000000000000000000001938 131.0
CMS2_k127_3490277_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2165.0
CMS2_k127_3490277_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 5.137e-221 692.0
CMS2_k127_3490277_10 Histidine kinase K13040 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000003387 239.0
CMS2_k127_3490277_11 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000002302 216.0
CMS2_k127_3490277_12 - - - - 0.000000000000000000000000000000000000000000000000000000000001221 222.0
CMS2_k127_3490277_13 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000008865 204.0
CMS2_k127_3490277_14 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000003731 200.0
CMS2_k127_3490277_15 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000007088 198.0
CMS2_k127_3490277_16 DnaK suppressor protein K06204 - - 0.00000000000000000000000000000000000000000003716 163.0
CMS2_k127_3490277_17 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000001742 166.0
CMS2_k127_3490277_18 two-component sensor histidine kinase - - - 0.000000000000000000000000000000000000000005313 175.0
CMS2_k127_3490277_19 Thioredoxin-like - - - 0.0000000000000000000000000000000000004385 147.0
CMS2_k127_3490277_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.343e-200 633.0
CMS2_k127_3490277_20 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000002623 145.0
CMS2_k127_3490277_21 - - - - 0.0000000000000000000193 93.0
CMS2_k127_3490277_22 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000007459 69.0
CMS2_k127_3490277_3 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 585.0
CMS2_k127_3490277_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 474.0
CMS2_k127_3490277_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 440.0
CMS2_k127_3490277_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 364.0
CMS2_k127_3490277_7 RecO N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004157 252.0
CMS2_k127_3490277_8 Histidine kinase K13040 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000008477 242.0
CMS2_k127_3490277_9 two-component sensor histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000003191 246.0
CMS2_k127_3516390_0 Mur ligase middle domain K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 595.0
CMS2_k127_3516390_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 551.0
CMS2_k127_3516390_10 Thiamine-binding protein - - - 0.00000000000000000000000000000000002129 137.0
CMS2_k127_3516390_11 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 0.000000000000000000007998 93.0
CMS2_k127_3516390_12 Ankyrin repeats (many copies) - - - 0.000000000008884 77.0
CMS2_k127_3516390_2 TRAP transporter, DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 518.0
CMS2_k127_3516390_3 Flagellar Assembly Protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 440.0
CMS2_k127_3516390_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 406.0
CMS2_k127_3516390_5 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 374.0
CMS2_k127_3516390_6 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 301.0
CMS2_k127_3516390_7 HIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 285.0
CMS2_k127_3516390_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000006944 226.0
CMS2_k127_3516390_9 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000000000000000000000000000000000006182 162.0
CMS2_k127_3537608_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1215.0
CMS2_k127_3537608_1 TaqI-like C-terminal specificity domain - - - 0.0 1084.0
CMS2_k127_3537608_2 abc transporter atp-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 331.0
CMS2_k127_3537608_3 ABC transporter K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 315.0
CMS2_k127_3537608_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 303.0
CMS2_k127_3537608_5 nucleotide-binding protein implicated in inhibition of septum formation K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002119 265.0
CMS2_k127_3537608_6 integral membrane protein - - - 0.000000000000000000000000000000000000000021 157.0
CMS2_k127_3552434_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1477.0
CMS2_k127_3552434_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000403 139.0
CMS2_k127_3602135_0 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 407.0
CMS2_k127_3602135_1 4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 364.0
CMS2_k127_3602135_2 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001313 244.0
CMS2_k127_3602135_3 - - - - 0.00000000000000000000000000000000000000000000000000000000008214 209.0
CMS2_k127_3602135_4 DnaJ domain protein K03686 - - 0.000000000000000000000000000000000000000006752 165.0
CMS2_k127_3602135_5 Endonuclease I K01150 - 3.1.21.1 0.0000000000000000000000000000006549 130.0
CMS2_k127_3625882_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 1.239e-261 811.0
CMS2_k127_3625882_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K15576 - - 2.777e-251 780.0
CMS2_k127_3625882_10 - - - - 0.00000000000000000000000000000000000000000000000000000000006278 219.0
CMS2_k127_3625882_11 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.0000000000000000000000000000000000000000000000001255 183.0
CMS2_k127_3625882_12 nitrate reductase K02570 - - 0.000000000000000000000000000000000000000000000005338 174.0
CMS2_k127_3625882_13 diguanylate cyclase K21020 - 2.7.7.65 0.0000000000000000000000000000000000002389 153.0
CMS2_k127_3625882_14 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.00000000000000000000000000000000000312 142.0
CMS2_k127_3625882_15 - - - - 0.0000000000003333 74.0
CMS2_k127_3625882_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 554.0
CMS2_k127_3625882_3 COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 433.0
CMS2_k127_3625882_4 ABC transporter K15555,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 417.0
CMS2_k127_3625882_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 317.0
CMS2_k127_3625882_6 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 287.0
CMS2_k127_3625882_7 General glycosylation pathway protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 286.0
CMS2_k127_3625882_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001151 259.0
CMS2_k127_3625882_9 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003184 248.0
CMS2_k127_3693055_0 MMPL family K07003 - - 3.839e-278 876.0
CMS2_k127_3693055_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.5e-234 730.0
CMS2_k127_3693055_10 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000401 148.0
CMS2_k127_3693055_11 7TM diverse intracellular signalling K20971 - - 0.00000000000000000000000000000000000112 158.0
CMS2_k127_3693055_12 Bacterial protein of unknown function (YtfJ_HI0045) K07109 - - 0.00000000000000000000000001337 117.0
CMS2_k127_3693055_14 FlaG protein K06603 - - 0.000000000000001167 82.0
CMS2_k127_3693055_15 - - - - 0.0000002636 56.0
CMS2_k127_3693055_16 - - - - 0.00004649 48.0
CMS2_k127_3693055_2 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 398.0
CMS2_k127_3693055_3 Sh3 type 3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 377.0
CMS2_k127_3693055_4 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 350.0
CMS2_k127_3693055_5 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 311.0
CMS2_k127_3693055_6 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.0000000000000000000000000000000000000000000000002341 194.0
CMS2_k127_3693055_7 Cytochrome c - - - 0.0000000000000000000000000000000000000008378 151.0
CMS2_k127_3693055_8 transcriptional regulator - - - 0.0000000000000000000000000000000000000102 152.0
CMS2_k127_3693055_9 flagellar protein FliS K02422 - - 0.00000000000000000000000000000000000005584 145.0
CMS2_k127_3743616_0 Acts as a magnesium transporter K06213 - - 9.705e-226 706.0
CMS2_k127_3743616_1 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 569.0
CMS2_k127_3743616_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 293.0
CMS2_k127_3743616_11 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007971 280.0
CMS2_k127_3743616_12 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006178 259.0
CMS2_k127_3743616_13 ABC transporter permease K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001985 253.0
CMS2_k127_3743616_14 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001386 249.0
CMS2_k127_3743616_15 response to heat K03808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000003701 203.0
CMS2_k127_3743616_16 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000008196 205.0
CMS2_k127_3743616_17 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000000009057 197.0
CMS2_k127_3743616_18 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000001224 194.0
CMS2_k127_3743616_19 Putative ATP-dependant zinc protease - - - 0.000000000000000000000000000000000000000000005364 167.0
CMS2_k127_3743616_2 Belongs to the RimK family K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 479.0
CMS2_k127_3743616_20 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000000000000003034 151.0
CMS2_k127_3743616_21 Small-conductance mechano-sensitive channel - - - 0.000000000000000000000000000000000002933 142.0
CMS2_k127_3743616_22 paraquat-inducible protein A K03808 - - 0.000000000000001848 84.0
CMS2_k127_3743616_24 molybdate ion transport K02017,K02019,K06857 - 3.6.3.29,3.6.3.55 0.000003116 54.0
CMS2_k127_3743616_3 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 471.0
CMS2_k127_3743616_4 PFAM peptidase M48 Ste24p K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 462.0
CMS2_k127_3743616_5 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 439.0
CMS2_k127_3743616_6 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 430.0
CMS2_k127_3743616_7 intermembrane lipid transfer K06192 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016020,GO:0016021,GO:0016043,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0071944,GO:0120009 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 379.0
CMS2_k127_3743616_8 PFAM ABC transporter K02017,K15497 - 3.6.3.29,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 331.0
CMS2_k127_3743616_9 CorA-like Mg2 transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 302.0
CMS2_k127_39282_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 525.0
CMS2_k127_39282_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 474.0
CMS2_k127_39282_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 361.0
CMS2_k127_39282_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 362.0
CMS2_k127_39282_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000001557 225.0
CMS2_k127_39282_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000005888 205.0
CMS2_k127_39282_6 ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000008366 190.0
CMS2_k127_39282_7 - - - - 0.000000000000000000000000000000000000000000000000001574 188.0
CMS2_k127_39282_8 Nitrogen fixation protein NifU - - - 0.00000000000000000000000000000000000000007233 152.0
CMS2_k127_39282_9 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000009021 76.0
CMS2_k127_3975636_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 452.0
CMS2_k127_3975636_1 Thioredoxin K03671 - - 0.000000000000000000000000000000001244 134.0
CMS2_k127_3975636_2 Protein of unknown function (DUF2905) - - - 0.00009202 45.0
CMS2_k127_4067371_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1035.0
CMS2_k127_4067371_1 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 461.0
CMS2_k127_4067371_10 protein conserved in bacteria - - - 0.000000000001434 78.0
CMS2_k127_4067371_2 chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000158 258.0
CMS2_k127_4067371_3 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000004519 209.0
CMS2_k127_4067371_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000005182 196.0
CMS2_k127_4067371_5 Outer membrane component of efflux system - - - 0.00000000000000000000000000000000000000000007176 175.0
CMS2_k127_4067371_6 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000001266 164.0
CMS2_k127_4067371_7 PFAM phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000003456 107.0
CMS2_k127_4067371_8 COG1309 Transcriptional regulator - - - 0.0000000000000001189 88.0
CMS2_k127_4067371_9 HD domain K07814 - - 0.000000000000001217 87.0
CMS2_k127_4072003_0 PFAM HI0933 family protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 426.0
CMS2_k127_4072003_1 Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) K00557 - 2.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 412.0
CMS2_k127_4072003_2 forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 355.0
CMS2_k127_4072003_3 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 348.0
CMS2_k127_4072003_4 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 325.0
CMS2_k127_4072003_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000001 179.0
CMS2_k127_4072003_6 PFAM EAL domain - - - 0.00000000000000000000001146 106.0
CMS2_k127_4072003_7 protein involved in exopolysaccharide biosynthesis - - - 0.00005068 54.0
CMS2_k127_4078725_0 Protein of unknown function (DUF1588) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 376.0
CMS2_k127_4078725_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 315.0
CMS2_k127_4078725_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000001658 155.0
CMS2_k127_4078725_3 Lipase (class 3) - - - 0.00000000000000000000000000000000007056 139.0
CMS2_k127_4078725_4 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000001125 89.0
CMS2_k127_4078725_5 Protein of unknown function (DUF3570) - - - 0.000000004248 68.0
CMS2_k127_4078725_6 Domain of unknown function (DUF4266) - - - 0.000005238 51.0
CMS2_k127_4108507_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 404.0
CMS2_k127_4108507_1 Extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001512 287.0
CMS2_k127_4108507_2 S4 domain K14761 - - 0.0000000000000000005882 88.0
CMS2_k127_4113847_0 ATP citrate synthase K15230 - 2.3.3.8 0.0 1005.0
CMS2_k127_4113847_1 Belongs to the succinate malate CoA ligase beta subunit family K15231 - 2.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 402.0
CMS2_k127_4124094_0 Belongs to the peptidase S41A family - - - 0.0000000000000000000000000000000000000000000000000000000001116 213.0
CMS2_k127_4125096_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 444.0
CMS2_k127_4125096_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005943 282.0
CMS2_k127_4125096_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001177 273.0
CMS2_k127_4125096_3 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000005069 220.0
CMS2_k127_4125096_4 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000166 208.0
CMS2_k127_4125096_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000003976 192.0
CMS2_k127_4125096_6 NYN domain - - - 0.0000000000000000000000000000000000000002235 158.0
CMS2_k127_4125096_7 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000003679 144.0
CMS2_k127_4125096_8 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000007432 150.0
CMS2_k127_4146763_0 Glycerol-3-phosphate dehydrogenase K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 524.0
CMS2_k127_4146763_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 303.0
CMS2_k127_4157157_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 346.0
CMS2_k127_4157157_1 permease K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 314.0
CMS2_k127_4157157_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000517 235.0
CMS2_k127_4157157_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000174 234.0
CMS2_k127_4167948_0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000002054 253.0
CMS2_k127_4167948_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003334 241.0
CMS2_k127_4167948_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000367 201.0
CMS2_k127_4167948_3 MerR HTH family regulatory protein - - - 0.000000000000000000000000000000000000000001387 159.0
CMS2_k127_4167948_4 - - - - 0.00000000000000000000000002812 111.0
CMS2_k127_4167948_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000607 66.0
CMS2_k127_4241063_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367,K00372,K08356 - 1.20.2.1,1.20.9.1,1.7.7.2 0.0 1179.0
CMS2_k127_4241063_1 Type I secretion system ATPase K12541 - - 1.54e-261 824.0
CMS2_k127_4241063_10 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 295.0
CMS2_k127_4241063_11 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 302.0
CMS2_k127_4241063_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004085 275.0
CMS2_k127_4241063_13 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001329 266.0
CMS2_k127_4241063_14 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001687 237.0
CMS2_k127_4241063_15 outer membrane protein, TolC family K12543 - - 0.00000000000000000000000000000000000000000000000000000000000002409 232.0
CMS2_k127_4241063_16 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000002249 202.0
CMS2_k127_4241063_17 domain protein K20276 - - 0.00000000000000000000000000000008011 145.0
CMS2_k127_4241063_18 PFAM FecR protein - - - 0.00000000000000000000000000002881 124.0
CMS2_k127_4241063_19 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000002695 89.0
CMS2_k127_4241063_2 COG0155 Sulfite reductase, beta subunit (hemoprotein) K00366,K00392 - 1.7.7.1,1.8.7.1 2.071e-254 799.0
CMS2_k127_4241063_20 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000002273 69.0
CMS2_k127_4241063_3 4Fe-4S dicluster domain K07307 - - 4.845e-215 679.0
CMS2_k127_4241063_4 COG2223 Nitrate nitrite transporter K02575 - - 1.262e-207 654.0
CMS2_k127_4241063_5 COG0631 Serine threonine protein phosphatase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 562.0
CMS2_k127_4241063_6 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 502.0
CMS2_k127_4241063_7 type I secretion membrane fusion protein, HlyD family K02022,K12542 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 441.0
CMS2_k127_4241063_8 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 416.0
CMS2_k127_4241063_9 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 402.0
CMS2_k127_4263146_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1048.0
CMS2_k127_4263146_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.569e-236 741.0
CMS2_k127_4263146_10 Cytochrome K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 421.0
CMS2_k127_4263146_11 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 404.0
CMS2_k127_4263146_12 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 398.0
CMS2_k127_4263146_13 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 385.0
CMS2_k127_4263146_14 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 374.0
CMS2_k127_4263146_15 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 333.0
CMS2_k127_4263146_16 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 338.0
CMS2_k127_4263146_17 Belongs to the 'phage' integrase family K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 293.0
CMS2_k127_4263146_18 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001225 285.0
CMS2_k127_4263146_19 abc transporter atp-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001515 278.0
CMS2_k127_4263146_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.146e-212 665.0
CMS2_k127_4263146_20 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005859 273.0
CMS2_k127_4263146_21 Belongs to the UPF0246 family K09861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006953 247.0
CMS2_k127_4263146_22 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000007447 244.0
CMS2_k127_4263146_23 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002739 240.0
CMS2_k127_4263146_24 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000004466 234.0
CMS2_k127_4263146_25 Flagellar biosynthetic protein fliR K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000007633 235.0
CMS2_k127_4263146_26 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000001282 235.0
CMS2_k127_4263146_27 protein conserved in bacteria K09778 - - 0.000000000000000000000000000000000000000000000000000000000003875 214.0
CMS2_k127_4263146_28 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000007045 185.0
CMS2_k127_4263146_29 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000006401 169.0
CMS2_k127_4263146_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.786e-204 643.0
CMS2_k127_4263146_30 Glycosyl transferase family, helical bundle domain - - - 0.00000000000000000000000000000000000000000003547 167.0
CMS2_k127_4263146_31 PFAM Fimbrial assembly family protein - - - 0.00000000000000000000000000000000000001139 150.0
CMS2_k127_4263146_32 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000141 151.0
CMS2_k127_4263146_33 - - - - 0.00000000000000000000000000000000001165 150.0
CMS2_k127_4263146_34 Protein of unknown function (DUF523) - - - 0.0000000000000000000000000000000001994 137.0
CMS2_k127_4263146_35 RESPONSE REGULATOR receiver K07288 - - 0.00000000000000000000000000000006645 142.0
CMS2_k127_4263146_36 Abortive infection protein - - - 0.0000000000000000000000000000001759 131.0
CMS2_k127_4263146_37 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000002556 121.0
CMS2_k127_4263146_38 - - - - 0.00000000000000000000000000004739 120.0
CMS2_k127_4263146_39 - - - - 0.000000000000000000000000001536 113.0
CMS2_k127_4263146_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 3.398e-200 629.0
CMS2_k127_4263146_40 - - - - 0.00000000000000000000000001473 116.0
CMS2_k127_4263146_41 esterase of the alpha beta hydrolase fold K07002 - - 0.0000000000000000000001404 104.0
CMS2_k127_4263146_42 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.00000000000000000102 96.0
CMS2_k127_4263146_43 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000006787 77.0
CMS2_k127_4263146_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 538.0
CMS2_k127_4263146_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 481.0
CMS2_k127_4263146_7 Protein of unknown function (DUF3373) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 484.0
CMS2_k127_4263146_8 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 468.0
CMS2_k127_4263146_9 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 424.0
CMS2_k127_4281764_0 ABC transporter K11085 - - 3.204e-195 623.0
CMS2_k127_4281764_1 flagellar hook-associated protein K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 494.0
CMS2_k127_4281764_11 Histidine Phosphotransfer domain - - - 0.0006993 48.0
CMS2_k127_4281764_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 401.0
CMS2_k127_4281764_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034,K12370 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 342.0
CMS2_k127_4281764_4 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000794 229.0
CMS2_k127_4281764_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000003515 221.0
CMS2_k127_4281764_6 - - - - 0.00000000000000000000000000000000000687 140.0
CMS2_k127_4281764_7 Rod binding protein - - - 0.00000000000000000000001665 102.0
CMS2_k127_4295779_0 Abc transporter K06158 - - 1.149e-284 885.0
CMS2_k127_4295779_1 Belongs to the DEAD box helicase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 590.0
CMS2_k127_4295779_10 - - - - 0.0000000000000000000005874 108.0
CMS2_k127_4295779_11 - - - - 0.0000000000004481 74.0
CMS2_k127_4295779_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K05910 - 1.11.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 560.0
CMS2_k127_4295779_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 393.0
CMS2_k127_4295779_4 Protein of unknown function (DUF808) K09781 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 381.0
CMS2_k127_4295779_5 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 302.0
CMS2_k127_4295779_6 Domain of unknown function (DUF386) - - - 0.000000000000000000000000000000000000000000000000007533 184.0
CMS2_k127_4295779_7 - - - - 0.000000000000000000000000000000000000002682 155.0
CMS2_k127_4295779_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000002906 139.0
CMS2_k127_4295779_9 helicase activity - - - 0.0000000000000000000001298 108.0
CMS2_k127_4308818_0 Oxidoreductase K00174 - 1.2.7.11,1.2.7.3 1.342e-197 620.0
CMS2_k127_4308818_1 Oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 508.0
CMS2_k127_4308818_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 460.0
CMS2_k127_4308818_3 oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 324.0
CMS2_k127_4308818_4 2-oxoglutarate acceptor oxidoreductase K00176 - 1.2.7.3 0.00000000000000000000000000000000000000000000001197 173.0
CMS2_k127_4308818_5 Heavy-metal-associated domain - - - 0.000000000000000000000000000005283 121.0
CMS2_k127_4308818_6 - - - - 0.000000000000000000000000002545 117.0
CMS2_k127_4308818_7 Protein of unknown function (DUF2892) - - - 0.00000000000005738 73.0
CMS2_k127_43365_0 - - - - 0.0 1093.0
CMS2_k127_43365_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 1.052e-229 724.0
CMS2_k127_43365_10 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 430.0
CMS2_k127_43365_11 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 389.0
CMS2_k127_43365_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 378.0
CMS2_k127_43365_13 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 353.0
CMS2_k127_43365_14 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 322.0
CMS2_k127_43365_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001911 262.0
CMS2_k127_43365_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000001777 232.0
CMS2_k127_43365_17 NADH-quinone oxidoreductase K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000009991 192.0
CMS2_k127_43365_18 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000008949 193.0
CMS2_k127_43365_19 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000002525 180.0
CMS2_k127_43365_2 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 1.422e-201 636.0
CMS2_k127_43365_20 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000007391 163.0
CMS2_k127_43365_21 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000003901 163.0
CMS2_k127_43365_22 Predicted metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000002635 154.0
CMS2_k127_43365_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000006967 132.0
CMS2_k127_43365_24 biopolymer transport protein K03559 - - 0.00000000000000000000000000009296 119.0
CMS2_k127_43365_25 cyclic nucleotide binding K21828 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000002208 94.0
CMS2_k127_43365_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000004119 87.0
CMS2_k127_43365_3 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 612.0
CMS2_k127_43365_4 Oxidoreductase K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 586.0
CMS2_k127_43365_5 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 571.0
CMS2_k127_43365_6 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 529.0
CMS2_k127_43365_7 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 470.0
CMS2_k127_43365_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 474.0
CMS2_k127_43365_9 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 460.0
CMS2_k127_44103_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 560.0
CMS2_k127_44103_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 462.0
CMS2_k127_44103_2 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000001834 156.0
CMS2_k127_44103_4 - - - - 0.0000004773 57.0
CMS2_k127_4423016_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.239e-256 809.0
CMS2_k127_4423016_1 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 308.0
CMS2_k127_4423016_2 Bacteriophage replication gene A protein (GPA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 304.0
CMS2_k127_4423016_3 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000001154 228.0
CMS2_k127_4423016_4 Belongs to the 'phage' integrase family K14059 - - 0.0000000000000000000000000000000000000000000000000000000000000018 232.0
CMS2_k127_4423016_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000009151 127.0
CMS2_k127_444907_0 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 565.0
CMS2_k127_444907_1 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 424.0
CMS2_k127_444907_2 Integrin alpha (beta-propellor repeats). - - - 0.00000002548 62.0
CMS2_k127_4523933_0 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains K02584 - - 3.473e-245 767.0
CMS2_k127_4523933_1 Amidohydrolase family - - - 3.297e-215 680.0
CMS2_k127_4523933_10 TIGRFAM SagB-type dehydrogenase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002613 286.0
CMS2_k127_4523933_11 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000000000000000000000000005704 198.0
CMS2_k127_4523933_12 NifQ K15790 - - 0.0000000000000000000000000000001095 126.0
CMS2_k127_4523933_13 ArsC family - - - 0.0000000000000000000000000000001698 128.0
CMS2_k127_4523933_14 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000002957 118.0
CMS2_k127_4523933_15 Cupin domain K11312 - - 0.0000000000000000000000001448 109.0
CMS2_k127_4523933_16 SnoaL-like domain - - - 0.0000000000000000000003432 109.0
CMS2_k127_4523933_18 - - - - 0.0000000000000000001135 93.0
CMS2_k127_4523933_19 - - - - 0.00000000000009449 76.0
CMS2_k127_4523933_2 COG0714 MoxR-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 526.0
CMS2_k127_4523933_20 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000002435 74.0
CMS2_k127_4523933_22 - - - - 0.000000007376 65.0
CMS2_k127_4523933_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 458.0
CMS2_k127_4523933_4 Putative metallopeptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 432.0
CMS2_k127_4523933_5 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 359.0
CMS2_k127_4523933_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 368.0
CMS2_k127_4523933_7 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 346.0
CMS2_k127_4523933_8 COG0433 Predicted ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 310.0
CMS2_k127_4523933_9 AhpC/TSA family K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001494 274.0
CMS2_k127_4606303_0 Alpha-2-Macroglobulin K06894 - - 0.0 1339.0
CMS2_k127_4606303_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 2.058e-216 695.0
CMS2_k127_4606303_2 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 413.0
CMS2_k127_4606303_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000004676 216.0
CMS2_k127_4606303_4 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000000000000000738 114.0
CMS2_k127_4606303_5 Ion transport protein - - - 0.0000001884 58.0
CMS2_k127_4608955_0 chemotaxis protein K03407 - 2.7.13.3 9.65e-281 878.0
CMS2_k127_4608955_1 PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain K03406,K05875 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 573.0
CMS2_k127_4608955_10 PAS fold K03776 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 383.0
CMS2_k127_4608955_11 hmm pf00563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 346.0
CMS2_k127_4608955_12 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 317.0
CMS2_k127_4608955_13 Fibronectin type 3 domain-containing protein K06882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 299.0
CMS2_k127_4608955_14 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000014 277.0
CMS2_k127_4608955_15 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002101 292.0
CMS2_k127_4608955_16 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004318 263.0
CMS2_k127_4608955_17 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000002839 247.0
CMS2_k127_4608955_18 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000007875 237.0
CMS2_k127_4608955_19 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000004827 236.0
CMS2_k127_4608955_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 512.0
CMS2_k127_4608955_20 Belongs to the 'phage' integrase family K14059 - - 0.0000000000000000000000000000000000000000000000000000000000005526 226.0
CMS2_k127_4608955_21 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000002929 210.0
CMS2_k127_4608955_22 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000000000000001019 207.0
CMS2_k127_4608955_23 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000001134 230.0
CMS2_k127_4608955_24 Chemotaxis protein CheW K03408 - - 0.00000000000000000000000000000000000000000000000000000003882 200.0
CMS2_k127_4608955_25 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000003005 188.0
CMS2_k127_4608955_26 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000147 179.0
CMS2_k127_4608955_27 HTH-like domain K07497 - - 0.000000000000000000000000000000000000000005339 155.0
CMS2_k127_4608955_28 outer membrane porin, OprD family - - - 0.000000000000000000000000000000000000000009379 169.0
CMS2_k127_4608955_29 Cell division protein FtsX K09811 - - 0.00000000000000000000000000000000000007517 153.0
CMS2_k127_4608955_3 type I restriction-modification system K03427 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 482.0
CMS2_k127_4608955_30 HD domain containing 3 K21138 GO:0003674,GO:0003824,GO:0006139,GO:0006152,GO:0006163,GO:0006195,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008893,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009154,GO:0009164,GO:0009166,GO:0009259,GO:0009261,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0015971,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0031667,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034035,GO:0034037,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046128,GO:0046130,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.7.2 0.0000000000000000000000000000000003263 138.0
CMS2_k127_4608955_32 Histidine kinase - - - 0.00000000000000001974 86.0
CMS2_k127_4608955_33 Helix-turn-helix - - - 0.0000000000000005846 79.0
CMS2_k127_4608955_34 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000008915 68.0
CMS2_k127_4608955_35 - - - - 0.0000001069 63.0
CMS2_k127_4608955_36 PFAM Integrase catalytic region K07497 - - 0.0002964 44.0
CMS2_k127_4608955_4 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 464.0
CMS2_k127_4608955_5 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 440.0
CMS2_k127_4608955_6 HTH-like domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 417.0
CMS2_k127_4608955_7 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 414.0
CMS2_k127_4608955_8 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 402.0
CMS2_k127_4608955_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 383.0
CMS2_k127_4630689_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1513.0
CMS2_k127_4630689_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6e-323 994.0
CMS2_k127_4630689_10 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 541.0
CMS2_k127_4630689_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 509.0
CMS2_k127_4630689_12 growth of symbiont in host cell K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 518.0
CMS2_k127_4630689_13 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 488.0
CMS2_k127_4630689_14 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 434.0
CMS2_k127_4630689_15 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 449.0
CMS2_k127_4630689_16 Belongs to the flagella basal body rod proteins family K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 409.0
CMS2_k127_4630689_17 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 403.0
CMS2_k127_4630689_18 Response regulator receiver K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 385.0
CMS2_k127_4630689_19 cation efflux system protein K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 372.0
CMS2_k127_4630689_2 Domain of unknown function (DUF1974) K06445 - - 5.093e-243 774.0
CMS2_k127_4630689_20 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 363.0
CMS2_k127_4630689_21 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 332.0
CMS2_k127_4630689_22 phage repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 317.0
CMS2_k127_4630689_23 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 317.0
CMS2_k127_4630689_24 flagellar basal body K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 298.0
CMS2_k127_4630689_25 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 299.0
CMS2_k127_4630689_26 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 287.0
CMS2_k127_4630689_27 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 292.0
CMS2_k127_4630689_28 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
CMS2_k127_4630689_29 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002305 284.0
CMS2_k127_4630689_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 4.479e-232 721.0
CMS2_k127_4630689_30 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002799 271.0
CMS2_k127_4630689_31 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000002923 251.0
CMS2_k127_4630689_32 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003294 235.0
CMS2_k127_4630689_33 uracil phosphoribosyltransferase K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000001611 232.0
CMS2_k127_4630689_34 Histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001147 235.0
CMS2_k127_4630689_35 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000007897 219.0
CMS2_k127_4630689_36 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000001831 214.0
CMS2_k127_4630689_37 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000321 212.0
CMS2_k127_4630689_38 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000004817 180.0
CMS2_k127_4630689_39 DnaJ domain protein K05801 - - 0.000000000000000000000000000000000000000000000146 177.0
CMS2_k127_4630689_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.674e-211 663.0
CMS2_k127_4630689_40 Bacterial transcriptional repressor C-terminal K16137 - - 0.0000000000000000000000000000000000000000002378 166.0
CMS2_k127_4630689_41 - - - - 0.000000000000000000000000000000000000003663 148.0
CMS2_k127_4630689_42 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000005842 145.0
CMS2_k127_4630689_43 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000001221 148.0
CMS2_k127_4630689_44 YtkA-like - - - 0.0000000000000000000000000000000001554 137.0
CMS2_k127_4630689_45 response regulator - - - 0.0000000000000000000000000000000002597 140.0
CMS2_k127_4630689_46 Ankyrin repeat - - - 0.0000000000000000000000000000000002966 137.0
CMS2_k127_4630689_47 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000001541 138.0
CMS2_k127_4630689_48 PFAM FecR protein - - - 0.000000000000000000000000000001852 134.0
CMS2_k127_4630689_49 - - - - 0.0000000000000000000000000008708 116.0
CMS2_k127_4630689_5 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 3.108e-205 661.0
CMS2_k127_4630689_50 Cytochrome c - - - 0.00000000000000000000000005581 110.0
CMS2_k127_4630689_51 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000006039 104.0
CMS2_k127_4630689_52 - - - - 0.000000000000000000006134 96.0
CMS2_k127_4630689_53 - - - - 0.000000000000000000008984 96.0
CMS2_k127_4630689_54 peptidoglycan-binding protein, lysm - - - 0.000000001365 68.0
CMS2_k127_4630689_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 588.0
CMS2_k127_4630689_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 584.0
CMS2_k127_4630689_8 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 565.0
CMS2_k127_4630689_9 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 562.0
CMS2_k127_4665400_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.172e-224 705.0
CMS2_k127_4665400_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 7.165e-198 623.0
CMS2_k127_4665400_10 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000682 244.0
CMS2_k127_4665400_11 dna polymerase iii K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000005522 214.0
CMS2_k127_4665400_12 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000002269 174.0
CMS2_k127_4665400_13 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000004771 150.0
CMS2_k127_4665400_14 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000001016 124.0
CMS2_k127_4665400_15 Histidine kinase K02658,K03407,K07814,K11527,K13040 - 2.7.13.3 0.000000000000000000000000000003481 138.0
CMS2_k127_4665400_16 protein-glutamate methylesterase activity K03413 - - 0.000000000000000443 83.0
CMS2_k127_4665400_17 - - - - 0.000000003954 59.0
CMS2_k127_4665400_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 567.0
CMS2_k127_4665400_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 503.0
CMS2_k127_4665400_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 506.0
CMS2_k127_4665400_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 507.0
CMS2_k127_4665400_6 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 423.0
CMS2_k127_4665400_7 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 333.0
CMS2_k127_4665400_8 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 325.0
CMS2_k127_4665400_9 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000125 297.0
CMS2_k127_4701624_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 1.036e-223 728.0
CMS2_k127_4701624_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 602.0
CMS2_k127_4701624_10 COGs COG1033 exporter of the RND superfamily protein K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 300.0
CMS2_k127_4701624_11 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 291.0
CMS2_k127_4701624_12 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006968 275.0
CMS2_k127_4701624_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002158 280.0
CMS2_k127_4701624_14 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006364 273.0
CMS2_k127_4701624_15 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005681 265.0
CMS2_k127_4701624_16 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008539 266.0
CMS2_k127_4701624_17 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000001295 233.0
CMS2_k127_4701624_18 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000002771 233.0
CMS2_k127_4701624_19 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000002129 217.0
CMS2_k127_4701624_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 605.0
CMS2_k127_4701624_20 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000000003855 201.0
CMS2_k127_4701624_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000009827 199.0
CMS2_k127_4701624_22 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000001009 186.0
CMS2_k127_4701624_23 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000001226 177.0
CMS2_k127_4701624_24 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000653 167.0
CMS2_k127_4701624_25 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000002812 169.0
CMS2_k127_4701624_26 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000000000000108 163.0
CMS2_k127_4701624_27 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000557 156.0
CMS2_k127_4701624_28 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000001333 147.0
CMS2_k127_4701624_29 - - - - 0.00000000000000000000000000000000000001991 159.0
CMS2_k127_4701624_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 491.0
CMS2_k127_4701624_30 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000002095 138.0
CMS2_k127_4701624_31 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000008623 121.0
CMS2_k127_4701624_32 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000001136 114.0
CMS2_k127_4701624_4 alanine dehydrogenase K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 452.0
CMS2_k127_4701624_5 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 414.0
CMS2_k127_4701624_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 398.0
CMS2_k127_4701624_7 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 376.0
CMS2_k127_4701624_8 ATPase (AAA K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 304.0
CMS2_k127_4701624_9 ribosomal protein L3 K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 291.0
CMS2_k127_4765356_0 two-component regulatory system Multi-sensor hybrid histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 346.0
CMS2_k127_4765356_1 Protein of unknown function (DUF3584) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 347.0
CMS2_k127_4765356_2 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000004343 271.0
CMS2_k127_4765356_3 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000000000000006358 163.0
CMS2_k127_4765356_4 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000000000000007019 131.0
CMS2_k127_4765356_5 regulation of response to stimulus K01406,K13730 - 3.4.24.40 0.00000000000000000000269 98.0
CMS2_k127_4765356_6 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000001464 89.0
CMS2_k127_497043_0 EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 384.0
CMS2_k127_497043_1 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 243.0
CMS2_k127_497043_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000001102 163.0
CMS2_k127_497043_3 protein conserved in bacteria K08682 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576 3.1.4.14 0.000000000000000000000000000000001416 138.0
CMS2_k127_497043_4 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000001473 124.0
CMS2_k127_497043_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000001592 88.0
CMS2_k127_5079114_0 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 637.0
CMS2_k127_5079114_1 Belongs to the peptidase S41A family - - - 0.000000000000000000000000000000000000000000000000002241 187.0
CMS2_k127_5093592_0 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 532.0
CMS2_k127_5093592_1 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 514.0
CMS2_k127_5093592_10 cytochrome c class I - - - 0.00000000000000000001305 96.0
CMS2_k127_5093592_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 424.0
CMS2_k127_5093592_3 dehydrogenase K00076 - 1.1.1.159 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 416.0
CMS2_k127_5093592_4 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 376.0
CMS2_k127_5093592_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002432 276.0
CMS2_k127_5093592_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000001668 233.0
CMS2_k127_5093592_8 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000006087 233.0
CMS2_k127_5093592_9 protein tyrosine phosphatase activity K01104,K19302 - 3.1.3.48,3.6.1.27 0.00000000000000000000000000000000000003334 149.0
CMS2_k127_5093959_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.902e-313 989.0
CMS2_k127_5093959_1 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 4.299e-298 938.0
CMS2_k127_5093959_10 Aminotransferase class I and II K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 313.0
CMS2_k127_5093959_11 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001246 272.0
CMS2_k127_5093959_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000002709 234.0
CMS2_k127_5093959_13 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000009398 197.0
CMS2_k127_5093959_14 (HIT) family - - - 0.000000000000000000000000000000000000000000000262 169.0
CMS2_k127_5093959_15 Protein conserved in bacteria - - - 0.0000000000000000000000002157 109.0
CMS2_k127_5093959_16 - - - - 0.000000000000000000000002197 108.0
CMS2_k127_5093959_17 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K20490 - - 0.000000000000000000000009693 107.0
CMS2_k127_5093959_18 Signal transduction protein - - - 0.00000000000000000000001699 116.0
CMS2_k127_5093959_19 - - - - 0.00000000000000001413 88.0
CMS2_k127_5093959_2 DinB superfamily K18912 - 1.14.99.50 4.998e-247 781.0
CMS2_k127_5093959_20 - - - - 0.00000000000000001964 82.0
CMS2_k127_5093959_21 Histone H1 - - - 0.00000002173 59.0
CMS2_k127_5093959_22 - - - - 0.0000001334 61.0
CMS2_k127_5093959_3 Belongs to the DEAD box helicase family K05592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 1.639e-203 646.0
CMS2_k127_5093959_4 GAF domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 626.0
CMS2_k127_5093959_5 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 574.0
CMS2_k127_5093959_6 cAMP phosphodiesterases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 531.0
CMS2_k127_5093959_7 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 393.0
CMS2_k127_5093959_8 DNA recombination protein K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 386.0
CMS2_k127_5093959_9 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 335.0
CMS2_k127_5104259_0 COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase K15022 - 1.17.1.10 0.0 1158.0
CMS2_k127_5104259_1 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1092.0
CMS2_k127_5104259_10 Belongs to the UPF0061 (SELO) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 612.0
CMS2_k127_5104259_11 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 605.0
CMS2_k127_5104259_12 COG4775 Outer membrane protein protective antigen OMA87 K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 557.0
CMS2_k127_5104259_13 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 552.0
CMS2_k127_5104259_14 Histidine kinase K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 545.0
CMS2_k127_5104259_15 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 511.0
CMS2_k127_5104259_16 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 494.0
CMS2_k127_5104259_17 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 492.0
CMS2_k127_5104259_18 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 471.0
CMS2_k127_5104259_19 Paralysed flagella protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 483.0
CMS2_k127_5104259_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1086.0
CMS2_k127_5104259_20 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 488.0
CMS2_k127_5104259_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 454.0
CMS2_k127_5104259_22 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 444.0
CMS2_k127_5104259_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 398.0
CMS2_k127_5104259_24 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 369.0
CMS2_k127_5104259_25 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 369.0
CMS2_k127_5104259_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 347.0
CMS2_k127_5104259_27 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 339.0
CMS2_k127_5104259_28 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 331.0
CMS2_k127_5104259_29 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 310.0
CMS2_k127_5104259_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1027.0
CMS2_k127_5104259_30 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 300.0
CMS2_k127_5104259_31 acid membrane antigen A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 302.0
CMS2_k127_5104259_32 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 297.0
CMS2_k127_5104259_33 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 308.0
CMS2_k127_5104259_34 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001615 243.0
CMS2_k127_5104259_35 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002072 247.0
CMS2_k127_5104259_36 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000003183 241.0
CMS2_k127_5104259_37 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000007001 208.0
CMS2_k127_5104259_38 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001019 190.0
CMS2_k127_5104259_39 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000002741 164.0
CMS2_k127_5104259_4 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 2.367e-307 958.0
CMS2_k127_5104259_40 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000001525 160.0
CMS2_k127_5104259_41 outer membrane porin, OprD family - - - 0.0000000000000000000000000000000000002975 156.0
CMS2_k127_5104259_42 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000001435 132.0
CMS2_k127_5104259_43 Putative thioesterase (yiiD_Cterm) - - - 0.00000000000000000000000000000001547 131.0
CMS2_k127_5104259_44 DNA-binding protein - - - 0.00000000000000000000000000000002245 127.0
CMS2_k127_5104259_45 Histidine kinase K03407 - 2.7.13.3 0.0000000000000000000000000000004474 128.0
CMS2_k127_5104259_46 (EAL) domain protein - - - 0.00000000000000000000000000002212 134.0
CMS2_k127_5104259_47 putative NADH-ubiquinone oxidoreductase chain E K00334 - 1.6.5.3 0.000000000000000000000000001968 112.0
CMS2_k127_5104259_48 SCO1/SenC K07152 - - 0.00000000000000000000000001275 116.0
CMS2_k127_5104259_5 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 4.056e-276 862.0
CMS2_k127_5104259_50 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000002585 86.0
CMS2_k127_5104259_52 - - - - 0.000001704 52.0
CMS2_k127_5104259_6 ATPase (AAA - - - 6.702e-252 789.0
CMS2_k127_5104259_7 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 2.514e-237 742.0
CMS2_k127_5104259_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.967e-223 695.0
CMS2_k127_5104259_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 2.121e-209 661.0
CMS2_k127_5109339_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.025e-286 904.0
CMS2_k127_5109339_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 5.211e-285 891.0
CMS2_k127_5109339_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 316.0
CMS2_k127_5109339_11 COGs COG3864 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004343 271.0
CMS2_k127_5109339_12 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001814 268.0
CMS2_k127_5109339_13 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000008809 245.0
CMS2_k127_5109339_14 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000004032 228.0
CMS2_k127_5109339_15 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000004409 234.0
CMS2_k127_5109339_16 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000001129 198.0
CMS2_k127_5109339_17 COG1214 Inactive homolog of metal-dependent proteases - - - 0.00000000000000000000000000000000000000001071 158.0
CMS2_k127_5109339_18 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000002552 151.0
CMS2_k127_5109339_19 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000004853 146.0
CMS2_k127_5109339_2 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 437.0
CMS2_k127_5109339_20 Domain of unknown function (DUF4389) - - - 0.00000000000005628 76.0
CMS2_k127_5109339_21 Fe2 transport system protein A K04758 - - 0.00000000000008966 73.0
CMS2_k127_5109339_22 nucleic-acid-binding protein implicated in transcription termination - - - 0.00000000002571 67.0
CMS2_k127_5109339_23 Predicted metal-dependent hydrolase K07044 - - 0.0000003612 55.0
CMS2_k127_5109339_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 392.0
CMS2_k127_5109339_4 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 385.0
CMS2_k127_5109339_5 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 366.0
CMS2_k127_5109339_6 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 342.0
CMS2_k127_5109339_7 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 323.0
CMS2_k127_5109339_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 349.0
CMS2_k127_5109339_9 riboflavin biosynthesis protein K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 323.0
CMS2_k127_5141220_0 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 402.0
CMS2_k127_5141220_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 375.0
CMS2_k127_5141220_11 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000004095 139.0
CMS2_k127_5141220_12 Domain of unknown function (DUF4389) - - - 0.00000000000007826 74.0
CMS2_k127_5141220_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001476 231.0
CMS2_k127_5141220_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002167 198.0
CMS2_k127_5141220_4 helicase activity K05592,K06877,K07462,K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000107 192.0
CMS2_k127_5141220_5 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000007025 168.0
CMS2_k127_5141220_6 cyclic nucleotide binding - - - 0.0000000000000000000000000000000000000000000009033 172.0
CMS2_k127_5141220_7 GGDEF domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000004342 171.0
CMS2_k127_5141220_8 - - - - 0.000000000000000000000000000000000000000005877 155.0
CMS2_k127_5141519_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1715.0
CMS2_k127_5141519_1 Belongs to the DNA mismatch repair MutS family K03555 - - 0.0 1230.0
CMS2_k127_5141519_10 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 515.0
CMS2_k127_5141519_11 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 515.0
CMS2_k127_5141519_12 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 492.0
CMS2_k127_5141519_13 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 380.0
CMS2_k127_5141519_14 Desulfoferrodoxin, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 365.0
CMS2_k127_5141519_15 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 380.0
CMS2_k127_5141519_16 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 359.0
CMS2_k127_5141519_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 335.0
CMS2_k127_5141519_18 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001742 280.0
CMS2_k127_5141519_19 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003642 269.0
CMS2_k127_5141519_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1145.0
CMS2_k127_5141519_20 GAF domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002213 276.0
CMS2_k127_5141519_21 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006856 254.0
CMS2_k127_5141519_22 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000227 256.0
CMS2_k127_5141519_23 Rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000001869 243.0
CMS2_k127_5141519_24 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000002528 261.0
CMS2_k127_5141519_25 methyl-accepting chemotaxis protein K03406,K05875 - - 0.00000000000000000000000000000000000000000000000000000000000000000001307 257.0
CMS2_k127_5141519_26 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000001955 229.0
CMS2_k127_5141519_27 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000001832 191.0
CMS2_k127_5141519_28 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000001196 193.0
CMS2_k127_5141519_29 - - - - 0.0000000000000000000000000000000000000000000005356 171.0
CMS2_k127_5141519_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 2.234e-262 817.0
CMS2_k127_5141519_30 L-threonylcarbamoyladenylate synthase - - - 0.0000000000000000000000000000003059 127.0
CMS2_k127_5141519_31 Chemotaxis protein CheY K03413 - - 0.000000000000000000000000007834 114.0
CMS2_k127_5141519_32 phospholipase K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000001064 117.0
CMS2_k127_5141519_33 membrane - - - 0.00000000000000000000000321 106.0
CMS2_k127_5141519_34 cysteine-type peptidase activity - - - 0.000000000000000000000005888 112.0
CMS2_k127_5141519_35 Thioesterase superfamily K10806 - - 0.0000000000000000000000727 103.0
CMS2_k127_5141519_36 Methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000004495 111.0
CMS2_k127_5141519_37 Belongs to the 'phage' integrase family K14059 - - 0.000000000000000000001383 95.0
CMS2_k127_5141519_38 - - - - 0.00000000000000000182 91.0
CMS2_k127_5141519_39 - - - - 0.000000000005243 72.0
CMS2_k127_5141519_4 Radical SAM - - - 1.214e-206 654.0
CMS2_k127_5141519_40 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000131 65.0
CMS2_k127_5141519_41 - - - - 0.0000003718 58.0
CMS2_k127_5141519_5 Bacterial protein of unknown function (DUF839) K07093 - - 1.035e-197 634.0
CMS2_k127_5141519_6 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.006e-195 617.0
CMS2_k127_5141519_7 rod shape-determining protein mreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 585.0
CMS2_k127_5141519_8 Glutathionylspermidine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 585.0
CMS2_k127_5141519_9 Sodium:sulfate symporter transmembrane region K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 587.0
CMS2_k127_5143948_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 - 2.7.7.6 0.0 2452.0
CMS2_k127_5143948_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2240.0
CMS2_k127_5143948_10 Aminotransferase K14261 - - 2.89e-212 664.0
CMS2_k127_5143948_11 peptidase U32 family K08303 - - 7.74e-212 665.0
CMS2_k127_5143948_12 homoserine dehydrogenase K00003 - 1.1.1.3 7.596e-195 614.0
CMS2_k127_5143948_13 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 621.0
CMS2_k127_5143948_14 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 556.0
CMS2_k127_5143948_15 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 541.0
CMS2_k127_5143948_16 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 500.0
CMS2_k127_5143948_17 Radical SAM protein K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 433.0
CMS2_k127_5143948_18 molybdopterin biosynthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 431.0
CMS2_k127_5143948_19 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 420.0
CMS2_k127_5143948_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1193.0
CMS2_k127_5143948_20 3-deoxy-d-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 407.0
CMS2_k127_5143948_21 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 376.0
CMS2_k127_5143948_22 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 396.0
CMS2_k127_5143948_23 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 371.0
CMS2_k127_5143948_24 histidinol phosphate phosphatase K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 357.0
CMS2_k127_5143948_25 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 354.0
CMS2_k127_5143948_26 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 329.0
CMS2_k127_5143948_27 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 328.0
CMS2_k127_5143948_28 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 310.0
CMS2_k127_5143948_29 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 323.0
CMS2_k127_5143948_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1059.0
CMS2_k127_5143948_30 Diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 321.0
CMS2_k127_5143948_31 Belongs to the pseudouridine synthase RluA family K06179,K06180 - 5.4.99.23,5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 299.0
CMS2_k127_5143948_32 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 295.0
CMS2_k127_5143948_33 dinuclear metal center protein, YbgI K22391 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000776 286.0
CMS2_k127_5143948_34 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001111 282.0
CMS2_k127_5143948_35 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 - 4.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001234 276.0
CMS2_k127_5143948_36 cAMP phosphodiesterases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002622 281.0
CMS2_k127_5143948_37 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001554 274.0
CMS2_k127_5143948_38 riboflavin synthase alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002144 272.0
CMS2_k127_5143948_39 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002285 273.0
CMS2_k127_5143948_4 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1019.0
CMS2_k127_5143948_40 COG1579 Zn-ribbon protein possibly nucleic acid-binding K07164,K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003311 271.0
CMS2_k127_5143948_41 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001206 269.0
CMS2_k127_5143948_42 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000003217 258.0
CMS2_k127_5143948_43 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008621 261.0
CMS2_k127_5143948_44 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001615 252.0
CMS2_k127_5143948_45 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000007957 248.0
CMS2_k127_5143948_46 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002237 239.0
CMS2_k127_5143948_47 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000005732 230.0
CMS2_k127_5143948_48 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000004095 233.0
CMS2_k127_5143948_49 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000383 224.0
CMS2_k127_5143948_5 glutamine synthetase K01915 - 6.3.1.2 7.196e-288 886.0
CMS2_k127_5143948_50 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004884 229.0
CMS2_k127_5143948_51 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000000002084 215.0
CMS2_k127_5143948_52 COG2346 Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000000000000000000000002625 208.0
CMS2_k127_5143948_53 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000001151 205.0
CMS2_k127_5143948_54 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000001464 192.0
CMS2_k127_5143948_55 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000001165 190.0
CMS2_k127_5143948_56 - - - - 0.0000000000000000000000000000000000000000000000000001072 196.0
CMS2_k127_5143948_57 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000272 193.0
CMS2_k127_5143948_58 Belongs to the P(II) protein family - - - 0.00000000000000000000000000000000000000000000000002308 181.0
CMS2_k127_5143948_59 Protein of unknown function (DUF3972) - - - 0.000000000000000000000000000000000000000000004611 168.0
CMS2_k127_5143948_6 Protein of unknown function (DUF1538) - - - 1.768e-259 812.0
CMS2_k127_5143948_60 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000005108 160.0
CMS2_k127_5143948_61 - - - - 0.000000000000000000000000000000000000004209 150.0
CMS2_k127_5143948_62 that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - 0.000000000000000000000000000000000000004266 161.0
CMS2_k127_5143948_63 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000005057 136.0
CMS2_k127_5143948_64 that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - 0.0000000000000000000000000000000002152 147.0
CMS2_k127_5143948_65 Protein conserved in bacteria - - - 0.000000000000000000000000000000004756 138.0
CMS2_k127_5143948_66 PAS domain - - - 0.0000000000000000000000000000000421 141.0
CMS2_k127_5143948_67 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000001495 126.0
CMS2_k127_5143948_68 regulatory protein TetR K16137 - - 0.00000000000000000000000000000266 127.0
CMS2_k127_5143948_69 PFAM FecR protein - - - 0.000000000000000000000000001218 122.0
CMS2_k127_5143948_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.297e-241 749.0
CMS2_k127_5143948_70 Thioredoxin - - - 0.00000000000000000000000002937 111.0
CMS2_k127_5143948_71 Protein of unknown function (DUF2393) - - - 0.00000000000000000000000006323 114.0
CMS2_k127_5143948_72 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000839 109.0
CMS2_k127_5143948_73 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000001967 116.0
CMS2_k127_5143948_74 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000005008 101.0
CMS2_k127_5143948_75 COG0840 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000004912 115.0
CMS2_k127_5143948_77 of the cytoplasmic domain of flagellar protein FhlB K04061 - - 0.0000000000000000001545 90.0
CMS2_k127_5143948_78 PDZ domain - - - 0.00000000000000002963 93.0
CMS2_k127_5143948_79 - - - - 0.00000000000000005709 85.0
CMS2_k127_5143948_8 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.017e-240 749.0
CMS2_k127_5143948_80 Protein of unknown function (DUF2393) - - - 0.00000000000000006133 87.0
CMS2_k127_5143948_81 Tetratricopeptide repeat - - - 0.0000000000000001052 87.0
CMS2_k127_5143948_82 - - - - 0.000000000001458 71.0
CMS2_k127_5143948_83 - - - - 0.000000000001654 71.0
CMS2_k127_5143948_84 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000003115 70.0
CMS2_k127_5143948_86 Protein of unknown function (DUF2393) - - - 0.000000001273 65.0
CMS2_k127_5143948_88 Protein of unknown function (DUF2393) - - - 0.0000005783 57.0
CMS2_k127_5143948_9 COG1070 Sugar (pentulose and hexulose) K11216 - 2.7.1.189 2.127e-222 701.0
CMS2_k127_5143948_91 - - - - 0.00001221 48.0
CMS2_k127_5143948_92 - - - - 0.0001358 49.0
CMS2_k127_5147428_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.574e-200 638.0
CMS2_k127_5147428_1 Arginosuccinate synthase K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 477.0
CMS2_k127_5147428_2 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 393.0
CMS2_k127_5147428_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000002958 207.0
CMS2_k127_5147428_4 PAP2 superfamily - - - 0.000000000000000000000000000000000000000001884 161.0
CMS2_k127_5147428_5 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000837 158.0
CMS2_k127_5147428_6 TonB dependent receptor - - - 0.00000000000000000000000000000000009965 140.0
CMS2_k127_5147428_7 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.0000002203 60.0
CMS2_k127_5147428_8 Protein of unknown function, DUF255 - - - 0.00006766 51.0
CMS2_k127_5147916_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.392e-309 959.0
CMS2_k127_5147916_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 599.0
CMS2_k127_5147916_10 lipopolysaccharide heptosyltransferase K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 309.0
CMS2_k127_5147916_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 300.0
CMS2_k127_5147916_12 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 293.0
CMS2_k127_5147916_13 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000251 260.0
CMS2_k127_5147916_14 Glycosyl transferase 4-like K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002436 254.0
CMS2_k127_5147916_15 Chemotaxis protein cheY K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000006269 220.0
CMS2_k127_5147916_16 lipid a biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000001997 187.0
CMS2_k127_5147916_17 PFAM O-Antigen K02847 - - 0.0000000000000000000000000000000000000000000000002544 191.0
CMS2_k127_5147916_18 GHKL domain - - - 0.0000000000000000000000000000000000000000000008336 172.0
CMS2_k127_5147916_19 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000129 136.0
CMS2_k127_5147916_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 580.0
CMS2_k127_5147916_20 - - - - 0.0000000000000000000000418 106.0
CMS2_k127_5147916_21 Histidine kinase K02482,K13040 - 2.7.13.3 0.000000000002548 76.0
CMS2_k127_5147916_22 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0004328 50.0
CMS2_k127_5147916_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 547.0
CMS2_k127_5147916_4 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 552.0
CMS2_k127_5147916_5 ADP-L-glycero-D-manno-heptose-6-epimerase K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 506.0
CMS2_k127_5147916_6 heptosyltransferase ii K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 404.0
CMS2_k127_5147916_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 397.0
CMS2_k127_5147916_8 General glycosylation pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 382.0
CMS2_k127_5147916_9 lipopolysaccharide core region biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 369.0
CMS2_k127_5149652_0 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 613.0
CMS2_k127_5149652_1 Membrane protease subunits - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 429.0
CMS2_k127_5149652_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 407.0
CMS2_k127_5149652_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006619 277.0
CMS2_k127_5149652_5 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000007648 109.0
CMS2_k127_5155517_0 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 614.0
CMS2_k127_5155517_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 561.0
CMS2_k127_5155517_10 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000000000000000000002769 176.0
CMS2_k127_5155517_11 Periplasmic Protein - - - 0.000000000000000000000000000000000000000003913 164.0
CMS2_k127_5155517_12 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000000000000000000001561 123.0
CMS2_k127_5155517_13 - - - - 0.00000000000000003059 83.0
CMS2_k127_5155517_14 - - - - 0.0005617 48.0
CMS2_k127_5155517_2 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 456.0
CMS2_k127_5155517_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 344.0
CMS2_k127_5155517_4 Two-component sensor histidine kinase response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 355.0
CMS2_k127_5155517_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 325.0
CMS2_k127_5155517_6 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007908 254.0
CMS2_k127_5155517_7 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000004763 228.0
CMS2_k127_5155517_8 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000001649 209.0
CMS2_k127_5155517_9 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000002684 190.0
CMS2_k127_5157658_0 UPF0313 protein - - - 0.0 1019.0
CMS2_k127_5157658_1 PFAM biotin lipoyl attachment domain-containing protein K01960 - 6.4.1.1 2.557e-316 975.0
CMS2_k127_5157658_10 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 493.0
CMS2_k127_5157658_11 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 466.0
CMS2_k127_5157658_12 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 380.0
CMS2_k127_5157658_13 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 375.0
CMS2_k127_5157658_14 Na H antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 353.0
CMS2_k127_5157658_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 321.0
CMS2_k127_5157658_16 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 291.0
CMS2_k127_5157658_17 membrane-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000293 211.0
CMS2_k127_5157658_18 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000006948 209.0
CMS2_k127_5157658_19 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000002776 211.0
CMS2_k127_5157658_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 7.72e-292 900.0
CMS2_k127_5157658_20 general stress protein - - - 0.000000000000000000000000000000000000000000000000000007093 194.0
CMS2_k127_5157658_21 Hit family K02503 - - 0.00000000000000000000000000000000000000000000001654 175.0
CMS2_k127_5157658_22 COGs COG3786 conserved - - - 0.0000000000000000000000000000000000000000000002691 175.0
CMS2_k127_5157658_23 PFAM secretion protein HlyD family protein - - - 0.000000000000000000000000000000000002708 148.0
CMS2_k127_5157658_24 - - - - 0.00000000000000000000000000000000001067 145.0
CMS2_k127_5157658_25 Histidine kinase K07645 - 2.7.13.3 0.0000000000000000000000001702 120.0
CMS2_k127_5157658_26 - - - - 0.00000000000000000001205 95.0
CMS2_k127_5157658_27 Outer membrane efflux protein - - - 0.000000000000000006258 87.0
CMS2_k127_5157658_28 - - - - 0.00000000002567 70.0
CMS2_k127_5157658_29 Oxaloacetate decarboxylase, gamma chain K01573 - 4.1.1.3 0.00000003091 59.0
CMS2_k127_5157658_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 2.778e-261 813.0
CMS2_k127_5157658_4 ribosomal protein S1 K02945 - - 3.233e-240 753.0
CMS2_k127_5157658_5 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 3.044e-231 739.0
CMS2_k127_5157658_6 COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit K01572 - 4.1.1.3 3.646e-208 654.0
CMS2_k127_5157658_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 602.0
CMS2_k127_5157658_8 molybdopterin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 518.0
CMS2_k127_5157658_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 509.0
CMS2_k127_5158149_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1023.0
CMS2_k127_5158149_1 DNA helicase K03657 - 3.6.4.12 3.441e-244 766.0
CMS2_k127_5158149_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 308.0
CMS2_k127_5158149_11 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 302.0
CMS2_k127_5158149_12 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
CMS2_k127_5158149_13 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000001008 201.0
CMS2_k127_5158149_15 - - - - 0.000000000000000000000000002596 114.0
CMS2_k127_5158149_17 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000004158 100.0
CMS2_k127_5158149_18 - - - - 0.00000000000004492 78.0
CMS2_k127_5158149_19 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.00000182 56.0
CMS2_k127_5158149_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 567.0
CMS2_k127_5158149_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 514.0
CMS2_k127_5158149_4 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 432.0
CMS2_k127_5158149_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 384.0
CMS2_k127_5158149_6 Histidine kinase K02482,K07710 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 376.0
CMS2_k127_5158149_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 361.0
CMS2_k127_5158149_8 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 356.0
CMS2_k127_5158149_9 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 316.0
CMS2_k127_5169157_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000008048 231.0
CMS2_k127_5169157_1 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000003987 182.0
CMS2_k127_5169157_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000312 142.0
CMS2_k127_5169157_4 oxygen carrier activity - - - 0.000000000000000000000000003361 114.0
CMS2_k127_5172941_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1520.0
CMS2_k127_5172941_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1062.0
CMS2_k127_5172941_10 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 337.0
CMS2_k127_5172941_11 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 328.0
CMS2_k127_5172941_12 Signal transduction protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 320.0
CMS2_k127_5172941_13 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001763 286.0
CMS2_k127_5172941_14 GAF domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000002021 262.0
CMS2_k127_5172941_15 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000001076 199.0
CMS2_k127_5172941_16 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000002288 197.0
CMS2_k127_5172941_17 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000001286 193.0
CMS2_k127_5172941_18 Membrane K08984 - - 0.00000000000000000000000000000000000000000000000005677 184.0
CMS2_k127_5172941_19 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000002385 179.0
CMS2_k127_5172941_2 Cytochrome c biogenesis protein - - - 4.282e-305 967.0
CMS2_k127_5172941_20 flagellar - - - 0.0000000000000000000000000000000000000000000001584 179.0
CMS2_k127_5172941_21 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000002204 174.0
CMS2_k127_5172941_22 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000004151 163.0
CMS2_k127_5172941_23 flagellar motor switch protein K02417 - - 0.0000000000000000000000000000000000000000426 154.0
CMS2_k127_5172941_24 NlpC/P60 family K13694,K13695 - 3.4.17.13 0.000000000000000000000000000000000001114 144.0
CMS2_k127_5172941_25 Chorismate mutase K04782 - 4.2.99.21 0.00000000000000000000000000000003698 128.0
CMS2_k127_5172941_26 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000004592 131.0
CMS2_k127_5172941_3 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 8.752e-304 938.0
CMS2_k127_5172941_4 Heterodisulfide reductase subunit B K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 502.0
CMS2_k127_5172941_5 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 514.0
CMS2_k127_5172941_6 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 484.0
CMS2_k127_5172941_7 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 397.0
CMS2_k127_5172941_8 na -driven multidrug efflux - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 373.0
CMS2_k127_5172941_9 Amino Acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 352.0
CMS2_k127_5181761_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000001079 123.0
CMS2_k127_5187236_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 3.12e-202 637.0
CMS2_k127_5187236_1 fructose-bisphosphate aldolase K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 601.0
CMS2_k127_5187236_11 Predicted membrane protein (DUF2231) - - - 0.00000000001137 71.0
CMS2_k127_5187236_2 4Fe-4S ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 406.0
CMS2_k127_5187236_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 322.0
CMS2_k127_5187236_4 Dipeptidase K01270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 304.0
CMS2_k127_5187236_5 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 286.0
CMS2_k127_5187236_6 Histidine kinase K20972 - - 0.000000000000000000000000000000000000000000000000000000000000000000001221 256.0
CMS2_k127_5187236_7 tRNA 3'-trailer cleavage K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000004645 244.0
CMS2_k127_5187236_8 peptidylprolyl isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000005015 232.0
CMS2_k127_5187236_9 1-aminocyclopropane-1-carboxylate deaminase K01505 - 3.5.99.7 0.000000000000000000000000000000000000000000000000000000000004023 218.0
CMS2_k127_5192828_0 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 344.0
CMS2_k127_5192828_1 cyclic nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000002602 226.0
CMS2_k127_5192828_2 COGs COG3920 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000001031 211.0
CMS2_k127_5192828_3 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000002266 173.0
CMS2_k127_5192934_0 chemotaxis protein K03407 - 2.7.13.3 0.0 1069.0
CMS2_k127_5192934_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1037.0
CMS2_k127_5192934_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 381.0
CMS2_k127_5192934_11 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 389.0
CMS2_k127_5192934_12 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 346.0
CMS2_k127_5192934_13 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 340.0
CMS2_k127_5192934_14 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 302.0
CMS2_k127_5192934_15 involved in molybdopterin and thiamine biosynthesis family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 283.0
CMS2_k127_5192934_16 DNA polymerase III K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000269 285.0
CMS2_k127_5192934_17 Belongs to the peptidase S41A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001035 290.0
CMS2_k127_5192934_18 Flagellar Assembly Protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000001504 252.0
CMS2_k127_5192934_19 chemotaxis protein K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000001204 228.0
CMS2_k127_5192934_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 4.156e-252 796.0
CMS2_k127_5192934_20 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000003184 233.0
CMS2_k127_5192934_21 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000811 211.0
CMS2_k127_5192934_22 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000003014 211.0
CMS2_k127_5192934_23 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000001492 188.0
CMS2_k127_5192934_24 - - - - 0.000000000000000000000000000000000000000000000009528 178.0
CMS2_k127_5192934_25 protein conserved in bacteria K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000001515 177.0
CMS2_k127_5192934_26 transformation system protein K02242 - - 0.0000000000000000000000000000000000000000000005939 172.0
CMS2_k127_5192934_27 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000006729 179.0
CMS2_k127_5192934_28 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000000004557 152.0
CMS2_k127_5192934_29 - - - - 0.00000000000000000000000000000000000000204 149.0
CMS2_k127_5192934_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 1.67e-196 618.0
CMS2_k127_5192934_30 Histidine kinase K13040 - 2.7.13.3 0.000000000000000000000000000000000000003785 163.0
CMS2_k127_5192934_32 - - - - 0.000000000000000000000000000000000002593 145.0
CMS2_k127_5192934_33 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000003723 139.0
CMS2_k127_5192934_34 - - - - 0.000000000000000000000000000000003018 136.0
CMS2_k127_5192934_35 spectrin binding - - - 0.0000000000000000000000002775 121.0
CMS2_k127_5192934_36 Metal-dependent hydrolase K07043 - - 0.0000000000000000000004308 104.0
CMS2_k127_5192934_37 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000116 84.0
CMS2_k127_5192934_38 OmpA family - - - 0.000000007611 68.0
CMS2_k127_5192934_39 - - - - 0.00008761 51.0
CMS2_k127_5192934_4 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 601.0
CMS2_k127_5192934_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 524.0
CMS2_k127_5192934_6 Ribonuclease K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 471.0
CMS2_k127_5192934_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 443.0
CMS2_k127_5192934_8 Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 407.0
CMS2_k127_5192934_9 chemotaxis protein K03415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 404.0
CMS2_k127_5224380_0 ATP-dependent CLP protease ATP-binding subunit K03694 - - 1.69e-297 929.0
CMS2_k127_5224380_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.157e-269 833.0
CMS2_k127_5224380_10 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000002381 218.0
CMS2_k127_5224380_11 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000003457 181.0
CMS2_k127_5224380_12 - - - - 0.000000000000000000000000000000000000000000000001449 178.0
CMS2_k127_5224380_13 TIGRFAM Diguanylate cyclase K02030,K03320 - - 0.0000000000000000000000000000000000000008583 162.0
CMS2_k127_5224380_14 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000004805 133.0
CMS2_k127_5224380_15 MOSC domain - - - 0.000000000000000000000000000005164 126.0
CMS2_k127_5224380_16 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.0000000000000001162 90.0
CMS2_k127_5224380_17 regulator - - - 0.00000008451 63.0
CMS2_k127_5224380_2 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 556.0
CMS2_k127_5224380_3 sulfate adenylyltransferase K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 540.0
CMS2_k127_5224380_4 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 424.0
CMS2_k127_5224380_5 4fe-4s ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 371.0
CMS2_k127_5224380_6 component of anaerobic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 283.0
CMS2_k127_5224380_7 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000268 253.0
CMS2_k127_5224380_8 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007401 246.0
CMS2_k127_5224380_9 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003379 239.0
CMS2_k127_5243624_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 5.117e-205 640.0
CMS2_k127_5243624_1 Signal transduction protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 308.0
CMS2_k127_5243624_2 Ribonuclease K12573 - - 0.000000000000000000000000001588 120.0
CMS2_k127_5253100_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 2.5e-254 807.0
CMS2_k127_5253100_1 Diguanylate cyclase - - - 2.334e-230 728.0
CMS2_k127_5253100_10 Belongs to the AAA ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 430.0
CMS2_k127_5253100_11 Na Pi-cotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 414.0
CMS2_k127_5253100_12 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 396.0
CMS2_k127_5253100_13 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 390.0
CMS2_k127_5253100_14 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 385.0
CMS2_k127_5253100_15 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 376.0
CMS2_k127_5253100_16 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 337.0
CMS2_k127_5253100_17 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 319.0
CMS2_k127_5253100_18 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 299.0
CMS2_k127_5253100_19 Transglutaminase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 315.0
CMS2_k127_5253100_2 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 1.044e-228 715.0
CMS2_k127_5253100_20 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 310.0
CMS2_k127_5253100_21 surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008047 284.0
CMS2_k127_5253100_22 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008824 248.0
CMS2_k127_5253100_23 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000000000000000000008837 241.0
CMS2_k127_5253100_24 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001075 234.0
CMS2_k127_5253100_25 Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000000000000000000000004732 172.0
CMS2_k127_5253100_26 GatB Yqey family protein K09117 - - 0.00000000000000000000000000000000000000000000004745 173.0
CMS2_k127_5253100_27 - - - - 0.0000000000000000000000000000000000000000000001262 172.0
CMS2_k127_5253100_28 TIGRFAM hemolysin TlyA family protein K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000005789 175.0
CMS2_k127_5253100_29 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000008858 171.0
CMS2_k127_5253100_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 597.0
CMS2_k127_5253100_30 COG0760 Parvulin-like peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000001429 151.0
CMS2_k127_5253100_31 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000000000000001226 125.0
CMS2_k127_5253100_32 Acyl-ACP thioesterase K07107 - - 0.0000000000000000000000000003132 119.0
CMS2_k127_5253100_33 MORN repeat protein - - - 0.000000000002008 80.0
CMS2_k127_5253100_34 Ankyrin repeat - - - 0.000003792 60.0
CMS2_k127_5253100_35 Belongs to the 'phage' integrase family K03111 - - 0.0004604 43.0
CMS2_k127_5253100_4 MiaB-like tRNA modifying enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 563.0
CMS2_k127_5253100_5 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 512.0
CMS2_k127_5253100_6 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 487.0
CMS2_k127_5253100_7 domain protein K09944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 460.0
CMS2_k127_5253100_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 447.0
CMS2_k127_5253100_9 Mate efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 443.0
CMS2_k127_5286371_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 4.278e-233 742.0
CMS2_k127_5286371_1 Belongs to the aldehyde dehydrogenase family - - - 3.709e-220 690.0
CMS2_k127_5286371_10 - - - - 0.0000000000002113 77.0
CMS2_k127_5286371_11 - - - - 0.000001356 51.0
CMS2_k127_5286371_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 550.0
CMS2_k127_5286371_3 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 500.0
CMS2_k127_5286371_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 420.0
CMS2_k127_5286371_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 328.0
CMS2_k127_5286371_6 phosphorelay signal transduction system K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000001929 138.0
CMS2_k127_5286371_7 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000001427 121.0
CMS2_k127_5286371_9 Unextendable partial coding region - - - 0.00000000000001092 74.0
CMS2_k127_5288395_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 606.0
CMS2_k127_5288395_1 PFAM Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 497.0
CMS2_k127_5288395_2 SPTR Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000001088 117.0
CMS2_k127_5288395_3 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000005574 83.0
CMS2_k127_5288564_0 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 389.0
CMS2_k127_5288564_1 COG0642 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006864 266.0
CMS2_k127_5308222_0 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 552.0
CMS2_k127_5308222_1 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 557.0
CMS2_k127_5308222_10 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000001033 170.0
CMS2_k127_5308222_11 PFAM FRG domain - - - 0.00000000000000000000000000000000000000001897 162.0
CMS2_k127_5308222_14 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000002853 154.0
CMS2_k127_5308222_15 - - - - 0.0000000000000000000001065 106.0
CMS2_k127_5308222_2 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 451.0
CMS2_k127_5308222_3 DNA methylase K00571,K07316 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 342.0
CMS2_k127_5308222_4 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 294.0
CMS2_k127_5308222_5 YaeQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001974 277.0
CMS2_k127_5308222_6 Domain of unknown function (DUF4405) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002309 281.0
CMS2_k127_5308222_8 RNase H - - - 0.000000000000000000000000000000000000000000000000002785 186.0
CMS2_k127_5312887_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 6.641e-246 762.0
CMS2_k127_5312887_1 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 2.163e-234 730.0
CMS2_k127_5312887_10 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.0000000000000000000000001233 117.0
CMS2_k127_5312887_11 - - - - 0.0000000000000000006303 89.0
CMS2_k127_5312887_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.042e-223 699.0
CMS2_k127_5312887_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 577.0
CMS2_k127_5312887_4 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 467.0
CMS2_k127_5312887_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 430.0
CMS2_k127_5312887_6 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 357.0
CMS2_k127_5312887_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000001108 166.0
CMS2_k127_5312887_8 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000004426 163.0
CMS2_k127_5312887_9 Flagellar biosynthetic protein FliQ K02420 - - 0.0000000000000000000000000000000403 126.0
CMS2_k127_5314998_0 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001029 269.0
CMS2_k127_5314998_2 COG0659 Sulfate permease and related K03321 - - 0.00000002535 55.0
CMS2_k127_5329352_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1157.0
CMS2_k127_5329352_1 Histidine kinase - - - 1.357e-317 1003.0
CMS2_k127_5329352_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000001033 178.0
CMS2_k127_5329352_11 Response regulator receiver K07814 - - 0.0000000000000000000000000000000000000001653 153.0
CMS2_k127_5329352_12 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K03776 - - 0.00000000000000000000000000000000000005406 147.0
CMS2_k127_5329352_13 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000000000000000000001251 145.0
CMS2_k127_5329352_14 RDD family - - - 0.0000000000000000000000000000000001647 138.0
CMS2_k127_5329352_15 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000001589 128.0
CMS2_k127_5329352_16 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.0000000000000000000000000004466 121.0
CMS2_k127_5329352_17 - - - - 0.00000000000000000000001018 106.0
CMS2_k127_5329352_18 GAF domain - - - 0.000000000000005452 82.0
CMS2_k127_5329352_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.449e-313 962.0
CMS2_k127_5329352_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 3.084e-206 659.0
CMS2_k127_5329352_4 COG1055 Na H antiporter NhaD and related arsenite - - - 6.477e-204 643.0
CMS2_k127_5329352_5 Belongs to the GARS family K01945 - 6.3.4.13 3.18e-203 639.0
CMS2_k127_5329352_6 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 574.0
CMS2_k127_5329352_7 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 334.0
CMS2_k127_5329352_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005785 273.0
CMS2_k127_5329352_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000002296 202.0
CMS2_k127_5331528_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1384.0
CMS2_k127_5331528_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.06e-257 797.0
CMS2_k127_5331528_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.377e-211 665.0
CMS2_k127_5331528_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 556.0
CMS2_k127_5331528_4 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 339.0
CMS2_k127_5331528_5 hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 302.0
CMS2_k127_5331528_6 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000004703 261.0
CMS2_k127_5331528_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000001811 66.0
CMS2_k127_5331528_9 - - - - 0.00006935 45.0
CMS2_k127_5355728_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K17050 - - 0.0 1587.0
CMS2_k127_5355728_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.095e-242 752.0
CMS2_k127_5355728_10 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 307.0
CMS2_k127_5355728_11 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001194 272.0
CMS2_k127_5355728_12 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000719 247.0
CMS2_k127_5355728_13 Nitrate reductase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001694 246.0
CMS2_k127_5355728_14 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000007298 239.0
CMS2_k127_5355728_15 - - - - 0.000000000000000000000000000000000000000000000000000798 196.0
CMS2_k127_5355728_16 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000595 182.0
CMS2_k127_5355728_17 PAS fold K03776 - - 0.0000000000000000000000000000000000000000001742 162.0
CMS2_k127_5355728_18 Serine hydrolase K07002 - - 0.0000000000000000000000000000000000000741 147.0
CMS2_k127_5355728_19 - - - - 0.000000000000000000000000000000001785 133.0
CMS2_k127_5355728_2 4Fe-4S dicluster domain K17051 - - 1.346e-227 706.0
CMS2_k127_5355728_20 Protein of unknown function (DUF493) - - - 0.0000000000000000003999 90.0
CMS2_k127_5355728_21 - - - - 0.000000000000000171 82.0
CMS2_k127_5355728_22 Glutathione peroxidase - - - 0.00000000000001357 81.0
CMS2_k127_5355728_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 519.0
CMS2_k127_5355728_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 507.0
CMS2_k127_5355728_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 493.0
CMS2_k127_5355728_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 453.0
CMS2_k127_5355728_7 RNA-binding protein homologous to eukaryotic snRNP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 373.0
CMS2_k127_5355728_8 Cytochrome c-552 DMSO reductase-like, heme-binding domain K17052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 364.0
CMS2_k127_5355728_9 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 338.0
CMS2_k127_5357586_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1192.0
CMS2_k127_5357586_1 Ammonium Transporter K03320 - - 3.098e-195 615.0
CMS2_k127_5357586_10 (Lipo)protein K09860 - - 0.000000000000000000000000000000002256 136.0
CMS2_k127_5357586_11 M42 glutamyl aminopeptidase - - - 0.00000000000000000002004 93.0
CMS2_k127_5357586_12 - - - - 0.00000000006988 67.0
CMS2_k127_5357586_13 PFAM Transposase IS3 IS911 - - - 0.00000003677 55.0
CMS2_k127_5357586_14 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000001464 61.0
CMS2_k127_5357586_15 Belongs to the 'phage' integrase family K14059 - - 0.000001469 53.0
CMS2_k127_5357586_16 - - - - 0.00006322 51.0
CMS2_k127_5357586_2 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 584.0
CMS2_k127_5357586_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 538.0
CMS2_k127_5357586_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 527.0
CMS2_k127_5357586_5 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 509.0
CMS2_k127_5357586_6 Receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 433.0
CMS2_k127_5357586_7 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 325.0
CMS2_k127_5357586_8 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000002239 201.0
CMS2_k127_5357586_9 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000002789 186.0
CMS2_k127_5441766_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1278.0
CMS2_k127_5441766_1 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 346.0
CMS2_k127_5441766_2 COG2200 FOG EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 323.0
CMS2_k127_5441766_3 PAS domain - - - 0.000000000000000000000000000000000000000000000000000004831 208.0
CMS2_k127_5441766_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000004913 164.0
CMS2_k127_5441766_5 - - - - 0.00000000000000001167 90.0
CMS2_k127_5441766_6 - - - - 0.0000000000000001028 84.0
CMS2_k127_5441766_7 Protein of unknown function (DUF3592) - - - 0.00000000009759 68.0
CMS2_k127_5498509_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.0 1101.0
CMS2_k127_5498509_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 2.842e-263 819.0
CMS2_k127_5498509_10 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 349.0
CMS2_k127_5498509_12 Ethylbenzene dehydrogenase K17052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 308.0
CMS2_k127_5498509_13 -acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 283.0
CMS2_k127_5498509_15 7TMR-DISM extracellular 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001723 267.0
CMS2_k127_5498509_16 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001535 248.0
CMS2_k127_5498509_17 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003681 240.0
CMS2_k127_5498509_18 Dtw domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001149 231.0
CMS2_k127_5498509_19 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000002966 228.0
CMS2_k127_5498509_2 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 7.026e-223 705.0
CMS2_k127_5498509_20 ubiquinol cytochrome c oxidoreductase, cytochrome c1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000001181 216.0
CMS2_k127_5498509_21 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000003359 211.0
CMS2_k127_5498509_22 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000001605 190.0
CMS2_k127_5498509_23 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000004402 189.0
CMS2_k127_5498509_24 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000001706 172.0
CMS2_k127_5498509_25 conserved protein (DUF2132) - - - 0.000000000000000000000000002506 112.0
CMS2_k127_5498509_26 - - - - 0.000000000000000000000007471 105.0
CMS2_k127_5498509_29 Domain of unknown function (DUF4405) - - - 0.000000000005436 67.0
CMS2_k127_5498509_3 the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 604.0
CMS2_k127_5498509_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 598.0
CMS2_k127_5498509_5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 557.0
CMS2_k127_5498509_6 Belongs to the glutaminase family K01425 - 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 480.0
CMS2_k127_5498509_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 402.0
CMS2_k127_5498509_8 Specifically methylates the adenine in position 1618 of 23S rRNA K06970 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052907,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 389.0
CMS2_k127_5498509_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 369.0
CMS2_k127_59120_0 AAA domain - - - 4.62e-204 657.0
CMS2_k127_59120_1 transport system permease component K02069 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003461 261.0
CMS2_k127_59120_2 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009242 260.0
CMS2_k127_59120_3 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001202 252.0
CMS2_k127_59120_4 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000003402 226.0
CMS2_k127_5984568_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 7.733e-218 679.0
CMS2_k127_5984568_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 531.0
CMS2_k127_5984568_10 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000003721 87.0
CMS2_k127_5984568_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 455.0
CMS2_k127_5984568_3 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 299.0
CMS2_k127_5984568_4 response regulator K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007581 263.0
CMS2_k127_5984568_5 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000003248 258.0
CMS2_k127_5984568_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000002558 231.0
CMS2_k127_5984568_7 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000589 217.0
CMS2_k127_5984568_8 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000001505 210.0
CMS2_k127_5984568_9 metal-binding, possibly nucleic acid-binding protein - - - 0.00000000000000000000000008732 110.0
CMS2_k127_603845_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1199.0
CMS2_k127_603845_1 RNA binding S1 domain protein K06959 - - 0.0 1054.0
CMS2_k127_603845_10 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 359.0
CMS2_k127_603845_11 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 302.0
CMS2_k127_603845_12 TIGRFAM channel protein, hemolysin III family K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002768 266.0
CMS2_k127_603845_13 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003025 266.0
CMS2_k127_603845_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001683 271.0
CMS2_k127_603845_15 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001786 251.0
CMS2_k127_603845_16 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000002018 239.0
CMS2_k127_603845_17 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000006176 205.0
CMS2_k127_603845_18 - - - - 0.000000000000000000000000000000000000000000483 165.0
CMS2_k127_603845_19 - - - - 0.0000000000000000000000000000000000000004017 153.0
CMS2_k127_603845_2 COG4548 Nitric oxide reductase activation protein K02448 - - 2.892e-251 788.0
CMS2_k127_603845_20 Transcriptional regulator - - - 0.000000000000000000000000000000000000001255 151.0
CMS2_k127_603845_21 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000006198 134.0
CMS2_k127_603845_22 Domain of unknown function (DUF1287) - - - 0.000000000000000000000001833 111.0
CMS2_k127_603845_23 Protein of unknown function (DUF1232) - - - 0.000000000000000000006974 96.0
CMS2_k127_603845_24 - - - - 0.0000000000000000002014 91.0
CMS2_k127_603845_3 Nitric oxide reductase K04561 - 1.7.2.5 2.152e-243 757.0
CMS2_k127_603845_4 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 1.634e-196 621.0
CMS2_k127_603845_5 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007977 501.0
CMS2_k127_603845_6 COG0714 MoxR-like K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 458.0
CMS2_k127_603845_7 Archaea bacterial proteins of unknown function K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 417.0
CMS2_k127_603845_8 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 410.0
CMS2_k127_603845_9 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 408.0
CMS2_k127_6120383_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1079.0
CMS2_k127_6120383_1 ABC transporter, ATP-binding protein K15738 - - 1.007e-277 867.0
CMS2_k127_6120383_10 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000003133 233.0
CMS2_k127_6120383_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002696 237.0
CMS2_k127_6120383_12 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000001357 164.0
CMS2_k127_6120383_13 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000005829 121.0
CMS2_k127_6120383_14 membrane - - - 0.00000000000000000000000002296 113.0
CMS2_k127_6120383_15 Domain of unknown function (DUF2018) - - - 0.00000000000000000001075 94.0
CMS2_k127_6120383_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.419e-213 670.0
CMS2_k127_6120383_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 592.0
CMS2_k127_6120383_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 463.0
CMS2_k127_6120383_5 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 417.0
CMS2_k127_6120383_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 356.0
CMS2_k127_6120383_7 abc transporter atp-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 330.0
CMS2_k127_6120383_8 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 331.0
CMS2_k127_6120383_9 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000005071 258.0
CMS2_k127_6121951_0 Acyltransferase K05939 - 2.3.1.40,6.2.1.20 0.0 1190.0
CMS2_k127_6121951_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 7.854e-309 957.0
CMS2_k127_6121951_10 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 436.0
CMS2_k127_6121951_11 flavin adenine dinucleotide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 382.0
CMS2_k127_6121951_12 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 342.0
CMS2_k127_6121951_13 Histidine kinase K13040 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 343.0
CMS2_k127_6121951_14 leucine binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 337.0
CMS2_k127_6121951_15 lytic murein transglycosylase K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 324.0
CMS2_k127_6121951_16 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 293.0
CMS2_k127_6121951_17 COGs COG0665 Glycine D-amino acid oxidase (deaminating) K15461 - 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000611 286.0
CMS2_k127_6121951_18 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000005976 255.0
CMS2_k127_6121951_19 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000171 256.0
CMS2_k127_6121951_2 Cation transporter/ATPase, N-terminus K01539 - 3.6.3.9 1.292e-296 934.0
CMS2_k127_6121951_20 Sodium calcium exchanger membrane K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005156 253.0
CMS2_k127_6121951_21 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000000000000007708 233.0
CMS2_k127_6121951_22 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000003209 230.0
CMS2_k127_6121951_23 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000003933 228.0
CMS2_k127_6121951_24 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000007406 213.0
CMS2_k127_6121951_25 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000002564 207.0
CMS2_k127_6121951_26 response to abiotic stimulus K21439 - - 0.0000000000000000000000000000000000000000000003603 170.0
CMS2_k127_6121951_27 thioesterase K07107 - - 0.000000000000000000000000000001307 124.0
CMS2_k127_6121951_28 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000005071 119.0
CMS2_k127_6121951_29 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000003538 123.0
CMS2_k127_6121951_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.17e-279 871.0
CMS2_k127_6121951_30 YGGT family K02221 - - 0.0000000000000000000000002378 108.0
CMS2_k127_6121951_31 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000000000000000000003926 101.0
CMS2_k127_6121951_32 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000005169 99.0
CMS2_k127_6121951_33 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000006103 93.0
CMS2_k127_6121951_34 - - - - 0.00000000000000007607 81.0
CMS2_k127_6121951_35 - - - - 0.000000000000001118 83.0
CMS2_k127_6121951_37 Family of unknown function (DUF695) - - - 0.0000000000003244 79.0
CMS2_k127_6121951_38 Bacterial regulatory proteins, tetR family - - - 0.000000007483 64.0
CMS2_k127_6121951_39 Protein of unknown function (DUF1566) - - - 0.000004995 55.0
CMS2_k127_6121951_4 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.136e-252 795.0
CMS2_k127_6121951_40 - - - - 0.000007789 49.0
CMS2_k127_6121951_41 chemotaxis protein K03406 - - 0.00001321 56.0
CMS2_k127_6121951_42 - - - - 0.00008509 44.0
CMS2_k127_6121951_5 Saccharopine dehydrogenase K00290 - 1.5.1.7 2.733e-234 727.0
CMS2_k127_6121951_6 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 7.038e-206 647.0
CMS2_k127_6121951_7 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 609.0
CMS2_k127_6121951_8 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 592.0
CMS2_k127_6121951_9 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 444.0
CMS2_k127_6164656_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.159e-269 836.0
CMS2_k127_6164656_1 Sulfate permease K03321 - - 1.296e-223 705.0
CMS2_k127_6164656_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 1.911e-196 617.0
CMS2_k127_6164656_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 401.0
CMS2_k127_6164656_4 7TMR-DISM extracellular 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 364.0
CMS2_k127_6164656_5 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002412 280.0
CMS2_k127_6164656_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000002381 130.0
CMS2_k127_6164656_7 Transposase, Mutator family - - - 0.0000000000000000357 82.0
CMS2_k127_6164656_8 McrBC 5-methylcytosine restriction system component K19147 - - 0.0003676 45.0
CMS2_k127_6213925_0 - - - - 0.00000000000000000000000000000000000000002644 159.0
CMS2_k127_6213925_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000001652 133.0
CMS2_k127_6213925_2 PadR family transcriptional regulator K10947 - - 0.0000002931 52.0
CMS2_k127_6214272_0 Cysteine desulfurase K04487 - 2.8.1.7 5.132e-222 692.0
CMS2_k127_6214272_1 ATP synthase K02412 - 3.6.3.14 1.529e-202 638.0
CMS2_k127_6214272_10 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000002404 213.0
CMS2_k127_6214272_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000001332 207.0
CMS2_k127_6214272_12 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.000000000000000000000000000000000000000006827 174.0
CMS2_k127_6214272_14 AI-2E family transporter - - - 0.00000000006862 70.0
CMS2_k127_6214272_2 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 548.0
CMS2_k127_6214272_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 488.0
CMS2_k127_6214272_4 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 445.0
CMS2_k127_6214272_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 398.0
CMS2_k127_6214272_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 330.0
CMS2_k127_6214272_7 GTP cyclohydrolase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 308.0
CMS2_k127_6214272_8 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 317.0
CMS2_k127_6214272_9 Histidine kinase K00936,K07315,K07679,K20977 - 2.7.13.3,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003632 276.0
CMS2_k127_62232_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1205.0
CMS2_k127_62232_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1182.0
CMS2_k127_62232_10 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 417.0
CMS2_k127_62232_11 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 421.0
CMS2_k127_62232_12 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 400.0
CMS2_k127_62232_13 metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 364.0
CMS2_k127_62232_14 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0003674,GO:0005488,GO:0005515,GO:0042802 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 359.0
CMS2_k127_62232_15 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 362.0
CMS2_k127_62232_16 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 318.0
CMS2_k127_62232_17 apolipoprotein N-acyltransferase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 327.0
CMS2_k127_62232_18 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 323.0
CMS2_k127_62232_19 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001957 273.0
CMS2_k127_62232_2 polysaccharide export protein KPSC K07266 - - 3.067e-236 748.0
CMS2_k127_62232_20 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000001242 242.0
CMS2_k127_62232_21 carbonic anhydrase K01674 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000001751 222.0
CMS2_k127_62232_22 - - - - 0.00000000000000000000000000000000000000000000000007496 179.0
CMS2_k127_62232_23 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.0000000000000000000000000000000000000001313 156.0
CMS2_k127_62232_24 Lipopolysaccharide-assembly - - - 0.00000000000000000000000000000000000002884 149.0
CMS2_k127_62232_25 - - - - 0.00000000000000000000000000000000003473 138.0
CMS2_k127_62232_26 Stress responsive A B Barrel Domain - - - 0.00000000000000000000000000003214 119.0
CMS2_k127_62232_27 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000009021 104.0
CMS2_k127_62232_28 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000001108 103.0
CMS2_k127_62232_29 competence protein K02237 - - 0.000000000001138 70.0
CMS2_k127_62232_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.519e-226 707.0
CMS2_k127_62232_30 Domain of unknown function (DUF4395) - - - 0.00000000002082 70.0
CMS2_k127_62232_31 outer membrane porin, OprD family - - - 0.00000000008269 74.0
CMS2_k127_62232_33 Pfam Glycosyl transferase family 2 K12990 - - 0.0004643 48.0
CMS2_k127_62232_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.406e-219 692.0
CMS2_k127_62232_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 3.268e-200 625.0
CMS2_k127_62232_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 596.0
CMS2_k127_62232_7 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 516.0
CMS2_k127_62232_8 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 456.0
CMS2_k127_62232_9 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 431.0
CMS2_k127_6471693_0 general secretion pathway protein D K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 488.0
CMS2_k127_6471693_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 355.0
CMS2_k127_6471693_2 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000006771 169.0
CMS2_k127_6471693_3 proline dehydrogenase activity - - - 0.00000000000000000000000000000000001101 147.0
CMS2_k127_6471693_4 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.000000000000000000001083 106.0
CMS2_k127_6471693_5 Prokaryotic N-terminal methylation motif - - - 0.0000000000000002027 86.0
CMS2_k127_6471693_6 - - - - 0.0000000000000008453 84.0
CMS2_k127_6471693_7 - - - - 0.0000000000001062 81.0
CMS2_k127_6471693_8 - - - - 0.0000001308 60.0
CMS2_k127_6501023_0 Transposase IS116 IS110 IS902 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 396.0
CMS2_k127_6511715_0 arginine decarboxylase K01585 - 4.1.1.19 8.261e-253 792.0
CMS2_k127_6511715_1 COGs COG0069 Glutamate synthase domain 2 - - - 8.066e-243 762.0
CMS2_k127_6511715_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 600.0
CMS2_k127_6511715_3 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 599.0
CMS2_k127_6511715_4 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 355.0
CMS2_k127_6511715_5 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000267 277.0
CMS2_k127_6511715_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000001446 254.0
CMS2_k127_6511715_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000006808 214.0
CMS2_k127_6511715_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000149 180.0
CMS2_k127_6511715_9 Chaperone for flagella basal body P-ring formation K02386 - - 0.000000000000000000000000000000000000007614 156.0
CMS2_k127_6527140_0 membrane K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004574 278.0
CMS2_k127_6527140_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001192 234.0
CMS2_k127_6527140_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000001588 166.0
CMS2_k127_6531796_0 Diguanylate cyclase - - - 6.941e-234 740.0
CMS2_k127_6531796_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000002381 165.0
CMS2_k127_6689606_0 abc transporter atp-binding protein - - - 1.323e-281 871.0
CMS2_k127_6689606_1 Glycolate oxidase subunit K00104 - 1.1.3.15 2.564e-263 814.0
CMS2_k127_6689606_10 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 341.0
CMS2_k127_6689606_11 GHKL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 336.0
CMS2_k127_6689606_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 312.0
CMS2_k127_6689606_13 S1 domain K00243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 311.0
CMS2_k127_6689606_14 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 298.0
CMS2_k127_6689606_15 Protein of unknown function (DUF3365) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 294.0
CMS2_k127_6689606_16 chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003259 291.0
CMS2_k127_6689606_17 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division K08306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004807 279.0
CMS2_k127_6689606_18 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000011 274.0
CMS2_k127_6689606_19 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009836 260.0
CMS2_k127_6689606_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.045e-219 696.0
CMS2_k127_6689606_20 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001522 263.0
CMS2_k127_6689606_21 Nudix domain K08077 - 3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000001528 237.0
CMS2_k127_6689606_22 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000008861 237.0
CMS2_k127_6689606_23 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000003825 230.0
CMS2_k127_6689606_24 COG2199 FOG GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000006902 219.0
CMS2_k127_6689606_25 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.00000000000000000000000000000000000000000000000005006 186.0
CMS2_k127_6689606_26 Domain of unknown function (DUF1987) - - - 0.0000000000000000000000000000000000000000001902 161.0
CMS2_k127_6689606_27 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000004878 158.0
CMS2_k127_6689606_28 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000008521 155.0
CMS2_k127_6689606_29 COG2202 FOG PAS PAC domain - - - 0.0000000000000000000000000000000000001486 146.0
CMS2_k127_6689606_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 4.328e-210 662.0
CMS2_k127_6689606_30 Plasminogen-binding protein pgbA N-terminal - - - 0.0000000000000000000000000000000000002712 149.0
CMS2_k127_6689606_31 Rhodanese-like domain - - - 0.0000000000000000000000000000000001042 136.0
CMS2_k127_6689606_32 Chemotaxis phosphatase CheX - - - 0.000000000000000000000000000000001563 146.0
CMS2_k127_6689606_34 - - - - 0.00000000000000000000000000000006293 131.0
CMS2_k127_6689606_35 SEC-C motif K09858 - - 0.000000000000000000000000000128 120.0
CMS2_k127_6689606_37 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000002828 84.0
CMS2_k127_6689606_38 Translation initiation factor SUI1 K03113 - - 0.0000000000002254 75.0
CMS2_k127_6689606_39 von Willebrand factor (vWF) type A domain - - - 0.00000000001219 72.0
CMS2_k127_6689606_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 557.0
CMS2_k127_6689606_40 PFAM DsrE DsrF-like family - - - 0.00000000003577 64.0
CMS2_k127_6689606_41 Pfam Colicin V production protein K03558 - - 0.000000001923 65.0
CMS2_k127_6689606_42 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.0001307 48.0
CMS2_k127_6689606_5 Hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 452.0
CMS2_k127_6689606_6 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 434.0
CMS2_k127_6689606_7 chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 406.0
CMS2_k127_6689606_8 peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 374.0
CMS2_k127_6689606_9 Belongs to the agmatine deiminase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 347.0
CMS2_k127_6823122_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 1.261e-256 807.0
CMS2_k127_6823122_1 abc transporter atp-binding protein K06147,K06148 - - 3.147e-224 708.0
CMS2_k127_6823122_2 molybdopterin biosynthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 440.0
CMS2_k127_6823122_3 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 426.0
CMS2_k127_6823122_4 molybdopterin converting factor K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000001525 244.0
CMS2_k127_6823122_5 Co Zn Cd efflux system component K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000001239 241.0
CMS2_k127_6823122_6 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000008717 231.0
CMS2_k127_6823122_7 molybdopterin converting factor K03636 - - 0.0000000000000000000000155 101.0
CMS2_k127_68402_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1320.0
CMS2_k127_68402_1 GTP-binding protein K06207 - - 0.0 1079.0
CMS2_k127_68402_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 454.0
CMS2_k127_68402_11 pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 456.0
CMS2_k127_68402_12 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 431.0
CMS2_k127_68402_13 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 375.0
CMS2_k127_68402_14 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 361.0
CMS2_k127_68402_15 Belongs to the pseudouridine synthase RluA family K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 349.0
CMS2_k127_68402_16 Flagellar basal body protein K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002011 289.0
CMS2_k127_68402_17 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000003931 263.0
CMS2_k127_68402_18 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002548 248.0
CMS2_k127_68402_19 Prolyl 4-hydroxylase alpha subunit homologues. K07394 - - 0.000000000000000000000000000000000000000000000000000000000000000000001978 243.0
CMS2_k127_68402_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 4.483e-262 810.0
CMS2_k127_68402_20 phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000775 235.0
CMS2_k127_68402_21 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000959 249.0
CMS2_k127_68402_22 Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000004472 199.0
CMS2_k127_68402_23 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000000000000000000000000000000000002608 201.0
CMS2_k127_68402_24 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000003148 197.0
CMS2_k127_68402_25 G T U mismatch-specific DNA glycosylase - - - 0.000000000000000000000000000000000000000001289 163.0
CMS2_k127_68402_26 TraB family K09973 - - 0.00000000000000000000000000000000000000005743 164.0
CMS2_k127_68402_27 Sel1-like repeats. - - - 0.000000000000000000000000000000000000002512 158.0
CMS2_k127_68402_28 CheC-like family K03410 - - 0.00000000000000000000000000000007057 132.0
CMS2_k127_68402_29 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000284 116.0
CMS2_k127_68402_3 Phospholipid glycerol acyltransferase - - - 1.986e-200 639.0
CMS2_k127_68402_30 cheY-homologous receiver domain - - - 0.00000000000000000000000000351 114.0
CMS2_k127_68402_31 Flagellar hook-length control protein FliK - - - 0.000000000000000000000005108 118.0
CMS2_k127_68402_32 Protein conserved in bacteria K09705 - - 0.00000000000000000000009435 99.0
CMS2_k127_68402_33 Protein of unknown function (DUF1697) - - - 0.0000000000000000000007121 100.0
CMS2_k127_68402_34 - - - - 0.0000000000000000001207 94.0
CMS2_k127_68402_36 Lysin motif - - - 0.000007621 56.0
CMS2_k127_68402_4 Flagellar hook protein flgE K02390 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 7.574e-199 642.0
CMS2_k127_68402_5 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 586.0
CMS2_k127_68402_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 546.0
CMS2_k127_68402_7 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 520.0
CMS2_k127_68402_8 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 498.0
CMS2_k127_68402_9 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 504.0
CMS2_k127_6841842_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 398.0
CMS2_k127_6841842_1 COG2166 SufE protein probably involved in Fe-S center assembly K02426 - - 0.00000000000000000000000000008884 120.0
CMS2_k127_6841842_2 FeS assembly SUF system protein SufT - - - 0.000000000000000000000000003392 114.0
CMS2_k127_6841842_3 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000538 94.0
CMS2_k127_6914867_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 486.0
CMS2_k127_6914867_1 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 382.0
CMS2_k127_6914867_10 - - - - 0.00000000000001387 79.0
CMS2_k127_6914867_11 3'-5' exonuclease activity on single or double-strand DNA K10857 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.0000000001368 63.0
CMS2_k127_6914867_2 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 369.0
CMS2_k127_6914867_3 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 334.0
CMS2_k127_6914867_4 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 317.0
CMS2_k127_6914867_5 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000001513 212.0
CMS2_k127_6914867_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000001406 199.0
CMS2_k127_6914867_7 response regulator - - - 0.000000000000000000000000000000000000000000000001067 182.0
CMS2_k127_6914867_8 - - - - 0.0000000000000000000000000000008063 127.0
CMS2_k127_6914867_9 cytochrome K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000004454 109.0
CMS2_k127_7019770_0 CheR methyltransferase, SAM binding domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 317.0
CMS2_k127_7034803_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.512e-304 942.0
CMS2_k127_7034803_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.755e-245 768.0
CMS2_k127_7034803_10 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000005278 220.0
CMS2_k127_7034803_11 - - - - 0.000000000000000000000000000000000000000000000000000001102 202.0
CMS2_k127_7034803_12 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000000003391 70.0
CMS2_k127_7034803_2 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 1.072e-236 737.0
CMS2_k127_7034803_3 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 1.189e-235 747.0
CMS2_k127_7034803_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 5.716e-220 691.0
CMS2_k127_7034803_5 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 417.0
CMS2_k127_7034803_6 abc transporter atp-binding protein K02031,K15587 - 3.6.3.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000715 281.0
CMS2_k127_7034803_7 PFAM sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001142 292.0
CMS2_k127_7034803_8 ubiquinol cytochrome c oxidoreductase, cytochrome c1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004941 275.0
CMS2_k127_7034803_9 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002478 277.0
CMS2_k127_842703_0 DNA helicase K03657 - 3.6.4.12 1.524e-276 867.0
CMS2_k127_842703_1 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 462.0
CMS2_k127_842703_10 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000461 136.0
CMS2_k127_842703_11 RNA-binding protein K06960 - - 0.00000000000000000000000153 104.0
CMS2_k127_842703_12 Global regulator protein family - - - 0.0000005419 54.0
CMS2_k127_842703_13 - - - - 0.0003443 44.0
CMS2_k127_842703_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 432.0
CMS2_k127_842703_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 338.0
CMS2_k127_842703_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 304.0
CMS2_k127_842703_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002744 274.0
CMS2_k127_842703_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000001303 194.0
CMS2_k127_842703_7 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000002948 191.0
CMS2_k127_842703_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000004969 189.0
CMS2_k127_842703_9 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000001446 181.0