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Overview

ID MAG00456
Name CMS2_bin.7
Sample SMP0011
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class E2
Order DHVEG-1
Family DHVEG-1
Genus SM1-50
Species
Assembly information
Completeness (%) 70.95
Contamination (%) 0.92
GC content (%) 45.0
N50 (bp) 3,873
Genome size (bp) 2,310,869

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1618

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1000470_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 496.0
CMS2_k127_101717_0 Methyltransferase - - - 0.0000000000001503 79.0
CMS2_k127_101717_1 Transglutaminase-like superfamily - - - 0.00000000001269 76.0
CMS2_k127_1018637_0 ATP binding K14862,K15173 GO:0000003,GO:0000226,GO:0000280,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006366,GO:0006369,GO:0006725,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007143,GO:0007276,GO:0007283,GO:0007292,GO:0008023,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0031974,GO:0031981,GO:0032501,GO:0032504,GO:0032774,GO:0032991,GO:0034453,GO:0034454,GO:0034641,GO:0034645,GO:0034654,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0044703,GO:0046483,GO:0048232,GO:0048285,GO:0048609,GO:0051321,GO:0051704,GO:0070013,GO:0071704,GO:0071840,GO:0072393,GO:0090304,GO:0097659,GO:0140013,GO:1901360,GO:1901362,GO:1901576,GO:1903046 - 0.0000000000000000002078 104.0
CMS2_k127_1018637_1 DNA-templated transcription, initiation K03120 GO:0000126,GO:0000428,GO:0000976,GO:0000977,GO:0000979,GO:0000981,GO:0000983,GO:0000988,GO:0000989,GO:0000995,GO:0001012,GO:0001016,GO:0001046,GO:0001047,GO:0001067,GO:0001075,GO:0001085,GO:0001091,GO:0001092,GO:0001098,GO:0001099,GO:0001102,GO:0001134,GO:0001179,GO:0001186,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005667,GO:0005669,GO:0005672,GO:0006139,GO:0006259,GO:0006351,GO:0006352,GO:0006355,GO:0006357,GO:0006359,GO:0006360,GO:0006366,GO:0006367,GO:0006383,GO:0006384,GO:0006725,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009303,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015074,GO:0016043,GO:0016070,GO:0016072,GO:0016591,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019904,GO:0022607,GO:0030880,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032196,GO:0032774,GO:0032991,GO:0033613,GO:0034622,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0042790,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043565,GO:0043933,GO:0044085,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044798,GO:0046483,GO:0050789,GO:0050794,GO:0051123,GO:0051171,GO:0051252,GO:0055029,GO:0060255,GO:0061695,GO:0065003,GO:0065004,GO:0065007,GO:0070013,GO:0070893,GO:0070897,GO:0070898,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090304,GO:0090575,GO:0090576,GO:0097159,GO:0097659,GO:0097718,GO:0098781,GO:0140110,GO:0140223,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1903506,GO:1990234,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000006282 83.0
CMS2_k127_1028873_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000004418 81.0
CMS2_k127_1033792_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 492.0
CMS2_k127_1033792_1 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 381.0
CMS2_k127_1033792_10 Ferric uptake regulator family K03711,K09825 - - 0.000000000000000000000000007647 115.0
CMS2_k127_1033792_11 protein conserved in archaea - - - 0.00000000000000000002765 93.0
CMS2_k127_1033792_12 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.000000002862 68.0
CMS2_k127_1033792_2 Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 300.0
CMS2_k127_1033792_3 Ferritin-like domain - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001265 278.0
CMS2_k127_1033792_4 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000001948 220.0
CMS2_k127_1033792_5 Desulfoferrodoxin, N-terminal domain K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000001828 196.0
CMS2_k127_1033792_6 - K07092 - - 0.0000000000000000000000000000000000000000000000000000002392 195.0
CMS2_k127_1033792_7 Ferritin-like domain K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000001151 197.0
CMS2_k127_1033792_8 Rubrerythrin - - - 0.00000000000000000000000000000000000004662 148.0
CMS2_k127_1033792_9 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000003267 124.0
CMS2_k127_1034971_0 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 325.0
CMS2_k127_1056035_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 1.092e-254 798.0
CMS2_k127_1056035_1 indolepyruvate ferredoxin oxidoreductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 445.0
CMS2_k127_1056035_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03388 - 1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 305.0
CMS2_k127_1056035_3 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000004066 262.0
CMS2_k127_1056035_4 Nitrate reductase gamma subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000006999 78.0
CMS2_k127_1057380_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000001816 199.0
CMS2_k127_1057380_1 PFAM helix-turn-helix HxlR type - - - 0.0000000000000000000000000000000000000000008363 159.0
CMS2_k127_1057380_2 Transcriptional regulator K07729 - - 0.000000000000000000000003263 104.0
CMS2_k127_1057380_3 4Fe-4S dicluster domain - - - 0.0000000000003986 68.0
CMS2_k127_1059094_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1427.0
CMS2_k127_1059094_1 ATPases associated with a variety of cellular activities K02003,K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007269 269.0
CMS2_k127_1059094_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008598 244.0
CMS2_k127_1059094_3 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 0.00007105 46.0
CMS2_k127_1065223_0 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 317.0
CMS2_k127_1065223_1 S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 K15450 - 2.1.1.282 0.000000000000000000000000000000000000000000166 165.0
CMS2_k127_1090218_0 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 417.0
CMS2_k127_1090218_1 Acyl-protein synthetase, LuxE - - - 0.00000000000000000000000000006666 132.0
CMS2_k127_1090218_2 PFAM General substrate transporter K08369 - - 0.000000000006211 77.0
CMS2_k127_109926_0 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.0000000000000000000000000000000000001452 159.0
CMS2_k127_1101078_0 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000008936 243.0
CMS2_k127_1101078_1 membrane - - - 0.000000009374 67.0
CMS2_k127_1107102_0 Belongs to the thymidine kinase family K00857 - 2.7.1.21 0.0000000000000001664 80.0
CMS2_k127_1109538_0 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001778 277.0
CMS2_k127_1109538_2 diguanylate cyclase activity - - - 0.000000000000000000000000000000000000002711 153.0
CMS2_k127_1109538_3 integral membrane protein - - - 0.0000000000003208 81.0
CMS2_k127_1127867_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 474.0
CMS2_k127_1127867_1 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000001377 157.0
CMS2_k127_1127867_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000003473 93.0
CMS2_k127_1127867_3 - - - - 0.000001689 53.0
CMS2_k127_1131463_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000003517 69.0
CMS2_k127_1140634_0 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 383.0
CMS2_k127_1140634_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 334.0
CMS2_k127_1140634_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K15583 - - 0.0000000000000000000000000000008052 123.0
CMS2_k127_1165503_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 475.0
CMS2_k127_1165503_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 286.0
CMS2_k127_1165503_2 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000002458 123.0
CMS2_k127_1165933_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 531.0
CMS2_k127_1165933_1 TIGRFAM TraB family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001499 291.0
CMS2_k127_1165933_2 - - - - 0.000000000000000000000000000000006623 137.0
CMS2_k127_1165933_3 Peptidase M50 - - - 0.0000000000000000000000000000001662 133.0
CMS2_k127_1165933_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000005013 83.0
CMS2_k127_1181891_0 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000007854 213.0
CMS2_k127_1181891_1 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000002312 179.0
CMS2_k127_1181891_2 Lrp/AsnC ligand binding domain - - - 0.0000000000000000001408 90.0
CMS2_k127_1181891_3 haloacid dehalogenase-like hydrolase K06019 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.1 0.000000000000007958 78.0
CMS2_k127_1181891_4 Periplasmic copper-binding protein (NosD) K07218 - - 0.00009947 54.0
CMS2_k127_1191701_0 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000001677 176.0
CMS2_k127_1191701_1 peroxiredoxin activity - - - 0.0000000000000000000000000000000000005814 142.0
CMS2_k127_1191701_2 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000001374 83.0
CMS2_k127_1193261_0 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 402.0
CMS2_k127_1193261_1 PFAM Glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 341.0
CMS2_k127_1193261_2 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.000000000000000002437 90.0
CMS2_k127_1202126_0 Right handed beta helix region - - - 0.00000000000000000524 96.0
CMS2_k127_1202126_1 Parallel beta-helix repeats - - - 0.0000000003033 70.0
CMS2_k127_1216640_0 Pfam:DUF650 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 477.0
CMS2_k127_1216640_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000369 237.0
CMS2_k127_1216640_3 methyltransferase - - - 0.000000000006527 76.0
CMS2_k127_1263804_0 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000001402 162.0
CMS2_k127_1263804_1 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000003573 161.0
CMS2_k127_1280944_0 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003185 275.0
CMS2_k127_1280944_1 acetyltransferase - - - 0.00000000000000000000003809 107.0
CMS2_k127_1280944_2 biotin apo-protein ligase-related - - - 0.0000755 52.0
CMS2_k127_1329549_0 Right handed beta helix region - - - 0.0000001935 64.0
CMS2_k127_1329549_2 Pfam:DUF1628 - - - 0.00003999 49.0
CMS2_k127_138041_0 distant relative of cell wall-associated - - - 0.0000000006153 70.0
CMS2_k127_1389708_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000392 221.0
CMS2_k127_1389708_1 snoRNA binding domain, fibrillarin K14564 - - 0.000000000000000000000000000000000000000000006394 174.0
CMS2_k127_1394316_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 507.0
CMS2_k127_1394316_1 Oxidoreductase family, C-terminal alpha beta domain K13016 - 1.1.1.335 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 442.0
CMS2_k127_1394316_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 377.0
CMS2_k127_1394316_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 372.0
CMS2_k127_1394316_4 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 366.0
CMS2_k127_1394316_5 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008129 237.0
CMS2_k127_1394316_6 Succinoglycan biosynthesis protein exoa - - - 0.000000000000000000000000000000000000000004548 168.0
CMS2_k127_1394572_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 295.0
CMS2_k127_1394572_1 HhH-GPD family K03575 - - 0.00000000000000000000000000000000000000000002698 167.0
CMS2_k127_1394572_2 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000001782 75.0
CMS2_k127_1399136_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 344.0
CMS2_k127_1455061_0 TIGRFAM Acetate-CoA ligase K01895 - 6.2.1.1 1.7e-280 875.0
CMS2_k127_146135_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000001396 236.0
CMS2_k127_146135_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000001073 219.0
CMS2_k127_146135_2 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000000000462 146.0
CMS2_k127_1468437_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 458.0
CMS2_k127_1468437_1 TIGRFAM geranylgeranyl reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005125 260.0
CMS2_k127_1468437_2 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000005522 214.0
CMS2_k127_1468437_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.00000000000000000000000000000000004059 137.0
CMS2_k127_1468437_4 - - - - 0.000000003136 63.0
CMS2_k127_1493977_0 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000004677 158.0
CMS2_k127_1493977_1 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.0000004302 60.0
CMS2_k127_1526297_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000005753 160.0
CMS2_k127_1526297_1 Protein conserved in bacteria - - - 0.00000000000000000007118 102.0
CMS2_k127_1539685_0 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 385.0
CMS2_k127_1539685_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000005258 92.0
CMS2_k127_1539685_2 Lipoate-protein ligase K03800 - 6.3.1.20 0.0000000000001315 78.0
CMS2_k127_154797_0 PFAM GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 451.0
CMS2_k127_1568405_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 310.0
CMS2_k127_1568405_1 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003613 276.0
CMS2_k127_1585006_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 291.0
CMS2_k127_1585006_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003527 268.0
CMS2_k127_1585006_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000005472 188.0
CMS2_k127_1635049_0 Penicillin amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002158 292.0
CMS2_k127_1635049_1 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.000006796 59.0
CMS2_k127_1635638_0 Uncharacterized metal-binding protein (DUF2227) - - - 0.0000000000000003845 86.0
CMS2_k127_16495_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000699 210.0
CMS2_k127_16495_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000001032 145.0
CMS2_k127_16495_2 Putative small multi-drug export protein - - - 0.000000000000000000000000000006211 124.0
CMS2_k127_1651028_0 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000001809 213.0
CMS2_k127_1651028_1 Putative esterase K07017 - - 0.0000000000000000000000000001065 124.0
CMS2_k127_1667144_0 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000002402 136.0
CMS2_k127_1667144_1 Protein of unknown function DUF116 - - - 0.00000000000000000000000001873 110.0
CMS2_k127_1676352_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 4.148e-220 695.0
CMS2_k127_1676352_1 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000001426 189.0
CMS2_k127_1676352_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000002782 96.0
CMS2_k127_1687884_0 Enoyl-CoA hydratase isomerase K07539 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 447.0
CMS2_k127_1687884_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000005158 255.0
CMS2_k127_1687884_2 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000621 224.0
CMS2_k127_1687884_3 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000005298 192.0
CMS2_k127_1687884_4 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000002974 174.0
CMS2_k127_1687884_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000001773 166.0
CMS2_k127_1687884_6 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.0000000000000000000002663 101.0
CMS2_k127_1687884_7 Transcriptional regulator K02019,K03574,K03750,K07219 - 2.10.1.1,3.6.1.55 0.0000000000000001119 84.0
CMS2_k127_1728529_0 Recombinase - - - 1.142e-260 822.0
CMS2_k127_1728529_2 transposition K07497 - - 0.0000000000001261 82.0
CMS2_k127_1731686_0 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000002377 230.0
CMS2_k127_1731686_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000009874 226.0
CMS2_k127_1736271_0 structural constituent of ribosome K02984 - - 0.000000000000000000000000000000000000000000000554 177.0
CMS2_k127_1743255_0 Peptidase family M28 K05994 - 3.4.11.10 0.0000000000000000000000000007343 129.0
CMS2_k127_1743255_1 cell wall organization - - - 0.0000000005318 70.0
CMS2_k127_1750391_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 359.0
CMS2_k127_1750391_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000006339 267.0
CMS2_k127_1750391_2 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000008697 234.0
CMS2_k127_1750391_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01464,K01465,K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.2,3.5.2.3,3.5.2.5 0.000000000000000002046 87.0
CMS2_k127_1751437_0 Belongs to the MT-A70-like family - - - 0.000000000000000000000000000000009162 133.0
CMS2_k127_177093_0 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000003925 161.0
CMS2_k127_177093_1 Haloacid dehalogenase-like hydrolase - - - 0.0008026 49.0
CMS2_k127_1773016_0 Small ubiquitin-related modifier K12160 - - 0.00000000000000000005004 92.0
CMS2_k127_1775835_0 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.00000000000000000000000000000000000000000000000000000004712 211.0
CMS2_k127_1788200_0 amine dehydrogenase activity - - - 0.000000000005935 78.0
CMS2_k127_1788200_1 toxin activity - - - 0.00000000005071 73.0
CMS2_k127_1805102_0 UbiA prenyltransferase family K03179,K17105 - 2.5.1.39,2.5.1.42 0.00000000008885 70.0
CMS2_k127_1805102_1 UbiA prenyltransferase family - - - 0.0002067 53.0
CMS2_k127_1836710_0 PFAM PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 347.0
CMS2_k127_1843190_0 pathogenesis K13669 - - 0.00000000001937 77.0
CMS2_k127_1843190_1 Domain of unknown function (DUF2341) - - - 0.00000006329 65.0
CMS2_k127_1891171_0 Nudix hydrolase - GO:0000166,GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009605,GO:0009607,GO:0009966,GO:0009967,GO:0010646,GO:0010647,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0023051,GO:0023056,GO:0035529,GO:0036094,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0047631,GO:0048037,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051287,GO:0051704,GO:0051707,GO:0065007,GO:0071944,GO:0080151,GO:0097159,GO:1901265,GO:1901363,GO:2000031,GO:2001023,GO:2001025,GO:2001038,GO:2001040 - 0.0006833 51.0
CMS2_k127_1895029_0 Response regulator, receiver K01007 - 2.7.9.2 5.867e-198 641.0
CMS2_k127_190390_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1597.0
CMS2_k127_190390_1 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 544.0
CMS2_k127_190390_2 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 464.0
CMS2_k127_190390_3 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 368.0
CMS2_k127_190390_4 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.000000000000000000000000000000000000000000000000000000000000000000008661 243.0
CMS2_k127_190390_5 PFAM HD domain K03698 - - 0.00000000000000000000000000000000000000000000000000000314 200.0
CMS2_k127_190390_6 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000000000003611 169.0
CMS2_k127_190390_7 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000001222 139.0
CMS2_k127_190390_8 Trm112p-like protein - - - 0.00000000000000017 80.0
CMS2_k127_1929610_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 353.0
CMS2_k127_1929610_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001998 271.0
CMS2_k127_19397_0 Transglutaminase-like superfamily - - - 0.0002231 53.0
CMS2_k127_1959372_0 Anion transporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 337.0
CMS2_k127_1964852_0 amine dehydrogenase activity - - - 0.0002586 53.0
CMS2_k127_1973589_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 416.0
CMS2_k127_1973589_1 - K03561,K12287 - - 0.00000000000000000000000000000002694 137.0
CMS2_k127_1973589_2 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.000001267 53.0
CMS2_k127_1974698_0 imidazolonepropionase activity K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 345.0
CMS2_k127_2035214_0 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008206 245.0
CMS2_k127_2038135_0 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 310.0
CMS2_k127_2038135_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 299.0
CMS2_k127_2038135_2 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000001492 251.0
CMS2_k127_2038135_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000204 224.0
CMS2_k127_2038135_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000001652 209.0
CMS2_k127_2063550_0 flagella protein K07327,K07328 - - 0.000000003125 65.0
CMS2_k127_2063550_1 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000000837 62.0
CMS2_k127_2063550_2 PFAM Flagella accessory C family protein K07822 - - 0.000002069 58.0
CMS2_k127_2065002_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 475.0
CMS2_k127_2065002_1 Glycerate kinase K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 323.0
CMS2_k127_2067492_0 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000000000003444 118.0
CMS2_k127_2081668_0 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 307.0
CMS2_k127_2081668_1 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000011 194.0
CMS2_k127_2081668_2 alginic acid biosynthetic process - - - 0.000000000000000000000000005193 128.0
CMS2_k127_2081668_3 - - - - 0.0000000000000000001189 95.0
CMS2_k127_2081668_4 UbiA prenyltransferase family K20616 - - 0.00000000000000001772 93.0
CMS2_k127_2081668_5 Domain of unknown function (DU1801) - - - 0.00000000000005738 73.0
CMS2_k127_2081668_6 - - - - 0.000000000001257 71.0
CMS2_k127_2086497_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 446.0
CMS2_k127_2086497_1 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000003922 183.0
CMS2_k127_2086497_2 PFAM Methionine synthase, vitamin-B12 independent K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.0000000000000000000000000000000000000000003876 169.0
CMS2_k127_2086497_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000001854 170.0
CMS2_k127_2086497_4 Lysine methyltransferase K02493 - 2.1.1.297 0.00000000000000000000000000000000000002762 152.0
CMS2_k127_2086497_5 Co Zn Cd efflux system component K16264 - - 0.000000000000000000000000000000000001338 145.0
CMS2_k127_2086497_6 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.0000000000000000000000000000000001176 139.0
CMS2_k127_2086497_7 OB-fold nucleic acid binding domain - - - 0.00000000000000000000162 104.0
CMS2_k127_2086497_8 Propeptide_C25 - - - 0.000000000000004838 89.0
CMS2_k127_2086497_9 thymidylate synthase K00560 - 2.1.1.45 0.00000374 53.0
CMS2_k127_2133438_0 Periplasmic copper-binding protein (NosD) - - - 0.000005756 55.0
CMS2_k127_2140425_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000084 164.0
CMS2_k127_2144132_0 TIGRFAM PAS sensor protein - - - 0.0000000000000000000000000000000000000000000000000000000000000006174 239.0
CMS2_k127_2144132_1 Family 5 K02035 - - 0.000000000000000000000000000000000000000007429 166.0
CMS2_k127_2144132_2 phosphorelay signal transduction system K07658 - - 0.0000000000000000000006034 100.0
CMS2_k127_2144132_3 COG1522 Transcriptional regulators - - - 0.000001159 60.0
CMS2_k127_2144132_4 In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha- aminoadipate (AAA) pathway K06154 - - 0.000008553 57.0
CMS2_k127_2144132_5 Purple acid Phosphatase, N-terminal domain - - - 0.0001663 48.0
CMS2_k127_2146924_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004348 272.0
CMS2_k127_2202150_0 regulation of protein targeting to vacuolar membrane K08515 GO:0000149,GO:0000323,GO:0001775,GO:0001906,GO:0001909,GO:0002228,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002278,GO:0002283,GO:0002285,GO:0002323,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002447,GO:0002449,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0002697,GO:0002699,GO:0002703,GO:0002705,GO:0002886,GO:0002888,GO:0003674,GO:0005484,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005765,GO:0005766,GO:0005767,GO:0005768,GO:0005770,GO:0005773,GO:0005774,GO:0005776,GO:0005783,GO:0005789,GO:0005794,GO:0005802,GO:0005886,GO:0006810,GO:0006869,GO:0006887,GO:0006888,GO:0006892,GO:0006893,GO:0006897,GO:0006906,GO:0006909,GO:0006911,GO:0006914,GO:0006928,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007017,GO:0007018,GO:0007034,GO:0007041,GO:0007275,GO:0007399,GO:0008021,GO:0008104,GO:0008150,GO:0008152,GO:0008333,GO:0009056,GO:0009986,GO:0009987,GO:0010008,GO:0010324,GO:0010646,GO:0010647,GO:0010720,GO:0010769,GO:0010770,GO:0010817,GO:0010876,GO:0010970,GO:0010975,GO:0010976,GO:0012505,GO:0012506,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016050,GO:0016192,GO:0016236,GO:0017156,GO:0017157,GO:0019905,GO:0022008,GO:0022411,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023056,GO:0030027,GO:0030101,GO:0030133,GO:0030135,GO:0030136,GO:0030139,GO:0030141,GO:0030154,GO:0030285,GO:0030658,GO:0030659,GO:0030662,GO:0030665,GO:0030666,GO:0030667,GO:0030670,GO:0030672,GO:0030705,GO:0031090,GO:0031091,GO:0031143,GO:0031201,GO:0031224,GO:0031252,GO:0031300,GO:0031301,GO:0031344,GO:0031346,GO:0031347,GO:0031349,GO:0031410,GO:0031902,GO:0031982,GO:0031984,GO:0032101,GO:0032103,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032984,GO:0032991,GO:0033003,GO:0033005,GO:0033006,GO:0033008,GO:0033036,GO:0033157,GO:0034196,GO:0034197,GO:0034613,GO:0034622,GO:0035493,GO:0035577,GO:0036230,GO:0042119,GO:0042175,GO:0042267,GO:0042582,GO:0042886,GO:0042995,GO:0043001,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043269,GO:0043270,GO:0043299,GO:0043300,GO:0043302,GO:0043304,GO:0043306,GO:0043307,GO:0043308,GO:0043312,GO:0043320,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044433,GO:0044437,GO:0044440,GO:0044444,GO:0044446,GO:0044456,GO:0044464,GO:0044754,GO:0045055,GO:0045087,GO:0045177,GO:0045184,GO:0045202,GO:0045321,GO:0045335,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045921,GO:0046649,GO:0046883,GO:0046887,GO:0046903,GO:0046907,GO:0047496,GO:0048193,GO:0048280,GO:0048284,GO:0048471,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048699,GO:0048731,GO:0048814,GO:0048856,GO:0048869,GO:0050727,GO:0050729,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050865,GO:0050867,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051094,GO:0051128,GO:0051130,GO:0051179,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051588,GO:0051590,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0051960,GO:0051962,GO:0060284,GO:0060341,GO:0060627,GO:0061024,GO:0061025,GO:0061919,GO:0061951,GO:0065003,GO:0065007,GO:0065008,GO:0070201,GO:0070382,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072384,GO:0072657,GO:0072659,GO:0080134,GO:0090087,GO:0090150,GO:0090174,GO:0090313,GO:0097352,GO:0097458,GO:0097708,GO:0098563,GO:0098588,GO:0098657,GO:0098791,GO:0098793,GO:0098796,GO:0098805,GO:0098827,GO:0098852,GO:0098876,GO:0099024,GO:0099111,GO:0099501,GO:0099503,GO:0099518,GO:0120025,GO:0120035,GO:1900006,GO:1900483,GO:1903305,GO:1903307,GO:1903335,GO:1903530,GO:1903532,GO:1903533,GO:1903593,GO:1903595,GO:1903827,GO:1905475,GO:1990778,GO:2000026 - 0.00000001793 59.0
CMS2_k127_2211088_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.256e-291 923.0
CMS2_k127_2211088_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000009077 135.0
CMS2_k127_2211088_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000001426 52.0
CMS2_k127_2215084_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 439.0
CMS2_k127_2215084_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000007147 203.0
CMS2_k127_2215084_2 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.00000000000000000000000000000000000000000000006747 175.0
CMS2_k127_2215084_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000001244 130.0
CMS2_k127_2215084_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0002154 53.0
CMS2_k127_222213_0 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000003599 143.0
CMS2_k127_222213_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000002405 100.0
CMS2_k127_222213_2 - - - - 0.000002935 51.0
CMS2_k127_222213_3 SCP-2 sterol transfer family - - - 0.00004945 50.0
CMS2_k127_222213_4 - - - - 0.0003129 47.0
CMS2_k127_2228420_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 1.469e-217 682.0
CMS2_k127_2228420_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 316.0
CMS2_k127_2228420_2 Asparaginase, N-terminal K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000445 228.0
CMS2_k127_2228420_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000003497 188.0
CMS2_k127_2229346_0 PFAM Papain family cysteine protease - - - 0.0000000000000000000000000000000000008337 151.0
CMS2_k127_2275565_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000001109 188.0
CMS2_k127_2275565_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000003014 134.0
CMS2_k127_2278719_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 583.0
CMS2_k127_2278719_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000002799 136.0
CMS2_k127_2285816_0 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000003456 224.0
CMS2_k127_2285816_1 - - - - 0.00000000000000000000000000000000000523 142.0
CMS2_k127_2285816_2 4-hydroxyphenylacetate - - - 0.00000000000000000000000152 106.0
CMS2_k127_2286012_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 454.0
CMS2_k127_2286012_1 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 304.0
CMS2_k127_2286012_2 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000009679 250.0
CMS2_k127_2286012_3 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000007746 192.0
CMS2_k127_2286012_4 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000003872 128.0
CMS2_k127_2286012_5 Papain family cysteine protease K11751,K14647 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000003414 134.0
CMS2_k127_2286012_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000002216 70.0
CMS2_k127_2286012_7 - - - - 0.0000002997 55.0
CMS2_k127_2286012_8 ribosomal small subunit binding - - - 0.0005173 52.0
CMS2_k127_2329013_0 GIY-YIG catalytic domain K15078 - - 0.000000004215 63.0
CMS2_k127_2329013_1 TRAF-like signal transducer - - - 0.0007466 49.0
CMS2_k127_2341593_0 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.000000000000002961 89.0
CMS2_k127_2341593_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - 0.00000001109 63.0
CMS2_k127_2343227_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 2.987e-194 614.0
CMS2_k127_2343227_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 534.0
CMS2_k127_2343227_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000001246 111.0
CMS2_k127_2343227_3 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000003906 80.0
CMS2_k127_2343227_4 Putative transposon-encoded protein (DUF2080) - - - 0.0000000000000005603 78.0
CMS2_k127_2343227_5 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.00000000000007603 75.0
CMS2_k127_2344704_0 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000000009631 208.0
CMS2_k127_2344704_1 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000007305 170.0
CMS2_k127_2353168_0 L-ribulose-5-phosphate 4-epimerase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000001053 185.0
CMS2_k127_2353168_1 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000001914 173.0
CMS2_k127_2353168_2 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.00000000002992 70.0
CMS2_k127_2365466_0 FAD binding domain K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 307.0
CMS2_k127_2365466_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 286.0
CMS2_k127_2366026_0 COG3209 Rhs family protein - - - 0.0000001741 62.0
CMS2_k127_2366142_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.316e-217 691.0
CMS2_k127_2366142_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 601.0
CMS2_k127_2366142_2 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 434.0
CMS2_k127_2366142_3 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000002135 220.0
CMS2_k127_2366142_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000002403 218.0
CMS2_k127_2366142_5 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000004081 211.0
CMS2_k127_2366142_6 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000007069 141.0
CMS2_k127_2366142_7 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.00000000000000000000000000000009932 126.0
CMS2_k127_2366142_8 Lysine exporter protein LysE YggA - - - 0.0000000000005343 73.0
CMS2_k127_2366142_9 Lysine exporter protein LysE YggA - - - 0.00001494 50.0
CMS2_k127_2377873_0 ferredoxin oxidoreductase, subunit alpha K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 428.0
CMS2_k127_2377873_1 FAD binding domain K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 401.0
CMS2_k127_2377873_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 329.0
CMS2_k127_2377873_3 ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 323.0
CMS2_k127_2377873_4 PFAM Pyruvate K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000001912 185.0
CMS2_k127_2377873_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000000008374 84.0
CMS2_k127_2409344_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1124.0
CMS2_k127_2409344_1 Cell division protein 48 (CDC48) domain 2 K13525 - - 9.199e-276 872.0
CMS2_k127_2409344_2 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000000000000000000000000000000001604 223.0
CMS2_k127_2409344_3 PRC-barrel domain - - - 0.000000000000002283 78.0
CMS2_k127_2409344_4 - - - - 0.00007398 52.0
CMS2_k127_2409344_5 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.0002773 49.0
CMS2_k127_2409398_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 425.0
CMS2_k127_2409398_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000003504 84.0
CMS2_k127_240965_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17870 - 1.6.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003865 272.0
CMS2_k127_240965_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000174 191.0
CMS2_k127_2431526_0 Associated with various cellular activities K03924,K04748,K09882 - 6.6.1.2 0.00000000000000000000003972 112.0
CMS2_k127_2431526_1 von Willebrand factor (vWF) type A domain - - - 0.000008696 59.0
CMS2_k127_2431577_0 COG1404 Subtilisin-like serine proteases K13276 - - 0.00000000000000000000000003384 128.0
CMS2_k127_2431577_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000004198 108.0
CMS2_k127_2431577_2 PFAM NHL repeat containing protein - - - 0.00000000000000001782 99.0
CMS2_k127_2431577_3 transposase K07497 - - 0.0009222 42.0
CMS2_k127_2451979_0 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 489.0
CMS2_k127_2451979_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 444.0
CMS2_k127_2451979_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000001877 194.0
CMS2_k127_2451979_3 Chlorophyllase enzyme - - - 0.00000000000000000000000000000000000007865 149.0
CMS2_k127_2452825_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 465.0
CMS2_k127_2452825_1 4 iron, 4 sulfur cluster binding K00196 - - 0.00000000000000000000000000000004245 130.0
CMS2_k127_2470564_0 endonuclease K00986 - 2.7.7.49 0.00002133 50.0
CMS2_k127_2475704_0 helix_turn_helix ASNC type K03719 - - 0.0001133 51.0
CMS2_k127_2476214_0 - - - - 0.0000000000000002978 81.0
CMS2_k127_2476214_1 Peptidase family C25 - - - 0.0000003608 63.0
CMS2_k127_2476214_2 TIGRFAM RHS repeat-associated core - - - 0.0001924 49.0
CMS2_k127_2493803_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000004707 76.0
CMS2_k127_2509629_0 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000006613 84.0
CMS2_k127_251206_0 Dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000004509 196.0
CMS2_k127_251206_2 Nitroreductase family - - - 0.0000957 46.0
CMS2_k127_2518325_0 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.000000000000000000000000000000000000000000000000000000000000000000001788 250.0
CMS2_k127_25219_0 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 424.0
CMS2_k127_25219_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000007385 249.0
CMS2_k127_25219_2 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000008676 228.0
CMS2_k127_25219_3 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000002291 136.0
CMS2_k127_25219_4 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000006051 79.0
CMS2_k127_25219_5 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000002905 77.0
CMS2_k127_2533574_0 Na H ion antiporter subunit K05569 - - 0.0000000000000000000000000000000000000000000000000000000000004674 216.0
CMS2_k127_2533574_1 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000000000000002465 132.0
CMS2_k127_2533574_2 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.000000000000000000002641 96.0
CMS2_k127_2533574_3 Membrane bound hydrogenase - - - 0.0000000000000000004505 90.0
CMS2_k127_2533574_4 Domain of unknown function (DUF4040) - - - 0.00000000000006798 74.0
CMS2_k127_2533574_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000006979 68.0
CMS2_k127_2533834_0 P-loop ATPase protein family K06958 - - 0.00002906 52.0
CMS2_k127_2554065_0 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000022 295.0
CMS2_k127_2554065_1 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000002355 181.0
CMS2_k127_2554065_2 Domain of unknown function (DU1801) - - - 0.000000000000000004777 85.0
CMS2_k127_2554065_3 PKD domain containing protein - - - 0.000000000000002969 90.0
CMS2_k127_2554065_4 Cold shock K03704 - - 0.000000000000008105 75.0
CMS2_k127_2554065_5 Peptidase family C25 - - - 0.00000004409 66.0
CMS2_k127_2554065_6 regulation of response to stimulus K13730 - - 0.000001205 60.0
CMS2_k127_2554065_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00001871 57.0
CMS2_k127_2554065_8 RHS Repeat - - - 0.0002198 51.0
CMS2_k127_2564214_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 371.0
CMS2_k127_2575227_0 protein heterodimerization activity - - - 0.00005465 50.0
CMS2_k127_2575227_1 Subtilase family - - - 0.00007186 53.0
CMS2_k127_2583370_0 - - - - 0.0005921 45.0
CMS2_k127_2598359_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 590.0
CMS2_k127_2599254_0 Pfam:DUF1628 - - - 0.0006797 48.0
CMS2_k127_2602824_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000683 286.0
CMS2_k127_2602824_1 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.0000001414 63.0
CMS2_k127_2608613_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 5.352e-248 777.0
CMS2_k127_2608613_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 363.0
CMS2_k127_2608613_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000756 66.0
CMS2_k127_2609352_0 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000002969 87.0
CMS2_k127_2614358_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000001848 216.0
CMS2_k127_2614358_1 membrane - - - 0.0001612 50.0
CMS2_k127_2620054_0 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 293.0
CMS2_k127_2620054_1 Phenazine biosynthesis protein PhzF - - - 0.00000000000000000000000000000000000000000000000000000000000000000006169 241.0
CMS2_k127_2641328_0 PFAM Fibronectin type III domain - - - 0.0000000000000000000000000005279 130.0
CMS2_k127_2664252_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 289.0
CMS2_k127_2664252_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000007637 208.0
CMS2_k127_2664252_2 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000001225 94.0
CMS2_k127_2664252_3 membrane - - - 0.00000000001989 73.0
CMS2_k127_268832_0 Pectate lyase - - - 0.00000001715 68.0
CMS2_k127_268832_1 PFAM PUA domain containing protein K07557 GO:0002927,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.6.1.97 0.000007562 48.0
CMS2_k127_2698036_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 297.0
CMS2_k127_2710894_0 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000000000000000001044 155.0
CMS2_k127_2710894_1 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000000000000000733 134.0
CMS2_k127_2710894_2 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000001388 87.0
CMS2_k127_272434_0 TIGRFAM segregation and condensation protein B K06024 - - 0.0000000000000000000000007891 109.0
CMS2_k127_2726180_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 304.0
CMS2_k127_2726180_1 alginic acid biosynthetic process - - - 0.00002717 56.0
CMS2_k127_2736971_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 477.0
CMS2_k127_2736971_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007161 258.0
CMS2_k127_2760641_0 FlgD Ig-like domain - - - 0.000000000003094 79.0
CMS2_k127_2760641_1 Peptidase family C25 - - - 0.00002887 56.0
CMS2_k127_2806143_0 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000001492 129.0
CMS2_k127_2806143_1 - - - - 0.000000000000131 84.0
CMS2_k127_2806143_2 - - - - 0.0004634 50.0
CMS2_k127_2815366_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 373.0
CMS2_k127_2815366_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000002114 130.0
CMS2_k127_2815366_2 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.000000000000000000007931 100.0
CMS2_k127_2866555_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 299.0
CMS2_k127_2866555_1 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000001015 195.0
CMS2_k127_2870501_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000003366 57.0
CMS2_k127_2871683_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 543.0
CMS2_k127_2871683_1 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.000000000000000000000000000000000000000000000000000000001272 204.0
CMS2_k127_288118_0 Transcriptional regulator - - - 0.000000000000000000000000009076 120.0
CMS2_k127_2890380_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 513.0
CMS2_k127_2890380_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 325.0
CMS2_k127_2901639_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 422.0
CMS2_k127_2901639_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000003086 66.0
CMS2_k127_2924605_0 Di-glucose binding within endoplasmic reticulum - - - 0.000000000000002144 89.0
CMS2_k127_2934777_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 368.0
CMS2_k127_2934777_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000638 206.0
CMS2_k127_2934777_2 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000000000000008551 184.0
CMS2_k127_2934777_3 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000000000002562 138.0
CMS2_k127_2934777_4 Electron transfer flavoprotein K03522 - - 0.0000000005667 62.0
CMS2_k127_2934777_5 dCTP deaminase activity K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.00001543 51.0
CMS2_k127_2983_0 amino acid activation for nonribosomal peptide biosynthetic process K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000003707 205.0
CMS2_k127_2983_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000002553 141.0
CMS2_k127_2983_2 COG1520 FOG WD40-like repeat - - - 0.0000000000000000005225 102.0
CMS2_k127_29865_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000002406 75.0
CMS2_k127_29865_1 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000001415 59.0
CMS2_k127_2988890_0 PQQ enzyme repeat K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000005555 196.0
CMS2_k127_3035445_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 317.0
CMS2_k127_305707_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 286.0
CMS2_k127_305707_1 Binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000002975 141.0
CMS2_k127_305707_2 Ribosomal protein S27E K02978 - - 0.0000000000000002336 79.0
CMS2_k127_305707_3 protein conserved in archaea K09723 - - 0.00000000004335 68.0
CMS2_k127_305707_4 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000004045 55.0
CMS2_k127_306386_0 Helix-turn-helix XRE-family like proteins K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000429 232.0
CMS2_k127_306386_1 Peptidase family C25 - - - 0.000006992 58.0
CMS2_k127_3064587_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000007599 162.0
CMS2_k127_3064587_1 DNA polymerase A domain K02335 - 2.7.7.7 0.000000000000002942 87.0
CMS2_k127_3064587_2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000001789 57.0
CMS2_k127_3065665_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 474.0
CMS2_k127_3065665_1 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000005483 241.0
CMS2_k127_3065665_2 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.000000000000000000000000000000000000000000000000000008649 195.0
CMS2_k127_3065665_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000002256 137.0
CMS2_k127_307792_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 461.0
CMS2_k127_307792_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 291.0
CMS2_k127_307792_2 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.000000000000000000000000000000000000000000000000000000000000007646 222.0
CMS2_k127_307792_3 thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000002437 208.0
CMS2_k127_307792_4 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000007231 206.0
CMS2_k127_307792_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000001186 184.0
CMS2_k127_307792_6 NUDIX domain - - - 0.000000000000000000000000000000001766 133.0
CMS2_k127_307792_7 - - - - 0.0000000000000000000000000008393 117.0
CMS2_k127_30847_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 320.0
CMS2_k127_3098170_0 catalase activity K03781 - 1.11.1.6 1.938e-260 809.0
CMS2_k127_3098170_1 Ferrous iron transport B domain protein K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 621.0
CMS2_k127_3098170_10 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000001483 52.0
CMS2_k127_3098170_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004159 261.0
CMS2_k127_3098170_3 FeoA K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004028 250.0
CMS2_k127_3098170_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000001816 218.0
CMS2_k127_3098170_5 - - - - 0.00000000000000000000000000000000000000000000000001955 189.0
CMS2_k127_3098170_6 Efflux ABC transporter permease protein K02004 - - 0.000000000000000000000000000000000000000000000001437 189.0
CMS2_k127_3098170_7 amine dehydrogenase activity - - - 0.000000000000000000001851 108.0
CMS2_k127_3098170_8 COG1361 S-layer domain - - - 0.0000000000000001813 92.0
CMS2_k127_3098170_9 - - - - 0.0000000001364 74.0
CMS2_k127_3104042_0 pyridoxal phosphate-dependent acyltransferase K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 447.0
CMS2_k127_3104042_1 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 311.0
CMS2_k127_3104042_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000002902 88.0
CMS2_k127_3146805_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 409.0
CMS2_k127_3146805_1 Short C-terminal domain K08982 - - 0.00000000000000000000003534 103.0
CMS2_k127_3196583_0 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.00000000000000000000000000000000000000000000000000000000000006071 232.0
CMS2_k127_3203395_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 8.646e-219 695.0
CMS2_k127_3203395_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 378.0
CMS2_k127_3203395_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000000131 187.0
CMS2_k127_3203395_3 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000002044 122.0
CMS2_k127_3203395_4 Belongs to the PDCD5 family K06875 - - 0.0000000000000000007326 90.0
CMS2_k127_3203395_5 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000001298 91.0
CMS2_k127_3203395_6 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.0000000000001462 71.0
CMS2_k127_3223377_0 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000283 173.0
CMS2_k127_3265198_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 294.0
CMS2_k127_3265198_1 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000002983 124.0
CMS2_k127_3290544_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000006014 254.0
CMS2_k127_3290544_1 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000003171 188.0
CMS2_k127_3290544_2 Lrp/AsnC ligand binding domain - - - 0.00000000000000000002134 91.0
CMS2_k127_3290544_3 - - - - 0.00000001724 59.0
CMS2_k127_3299440_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 9.198e-226 717.0
CMS2_k127_3299440_1 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003614 262.0
CMS2_k127_3299440_2 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000103 224.0
CMS2_k127_3305855_0 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.0000000000000000001689 97.0
CMS2_k127_3305855_1 fosmidomycin resistance protein K08223 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001999 61.0
CMS2_k127_3305923_0 Glucose / Sorbosone dehydrogenase - - - 0.000005406 57.0
CMS2_k127_3308647_0 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000001758 181.0
CMS2_k127_3319412_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 544.0
CMS2_k127_3319412_2 Bacterial Ig-like domain (group 3) - - - 0.0000005124 63.0
CMS2_k127_3319412_3 deoxyhypusine monooxygenase activity - - - 0.00001119 52.0
CMS2_k127_3325591_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 323.0
CMS2_k127_3325591_1 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000000004834 205.0
CMS2_k127_3325591_2 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.000000000000000000000000000000000000000001247 160.0
CMS2_k127_3331816_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.983e-217 687.0
CMS2_k127_3331816_1 - - - - 0.00000000007738 74.0
CMS2_k127_3332441_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 312.0
CMS2_k127_3332441_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000005289 250.0
CMS2_k127_3332441_2 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000000002509 223.0
CMS2_k127_3332441_3 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.00000000000000000000000000000000000006495 149.0
CMS2_k127_3332441_4 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.000000000000000000000000000907 130.0
CMS2_k127_3332441_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000006962 53.0
CMS2_k127_3332441_6 COG0170 Dolichol kinase - - - 0.0002049 52.0
CMS2_k127_3363117_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 376.0
CMS2_k127_3363117_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 287.0
CMS2_k127_3364250_0 KH domain K07041 - - 8.381e-261 817.0
CMS2_k127_3364250_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000001206 154.0
CMS2_k127_3370373_2 Chaperone of endosialidase - - - 0.0002436 54.0
CMS2_k127_3371279_0 resolution of meiotic recombination intermediates - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 469.0
CMS2_k127_3371279_1 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.000000000000000000000000001216 120.0
CMS2_k127_3371279_2 saccharopine dehydrogenase activity K00293,K14157 GO:0003674,GO:0003824,GO:0004753,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.10,1.5.1.8,1.5.1.9 0.00000002273 56.0
CMS2_k127_3371279_3 - - - - 0.00006689 49.0
CMS2_k127_3373300_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 331.0
CMS2_k127_3390150_0 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000002086 113.0
CMS2_k127_3390150_1 Microtubule binding - - - 0.0000004251 64.0
CMS2_k127_3390150_2 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000003709 57.0
CMS2_k127_3394234_0 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 452.0
CMS2_k127_3394234_1 PFAM Acyl-CoA dehydrogenase K00248,K22430 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108,1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 435.0
CMS2_k127_3394234_2 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001997 289.0
CMS2_k127_3395306_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.000000000000000000000000000000000000002837 154.0
CMS2_k127_3395306_1 NADH dehydrogenase - - - 0.0000000000000000000000000000000000003966 144.0
CMS2_k127_3395306_2 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000004216 98.0
CMS2_k127_3395306_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000002986 79.0
CMS2_k127_3416090_0 Cysteinyl-tRNA synthetase K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 476.0
CMS2_k127_3416090_1 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000004817 227.0
CMS2_k127_3416090_2 PFAM UspA domain protein - - - 0.0000000000006601 74.0
CMS2_k127_3416090_3 ribosomal protein S15 K02956 - - 0.0000004986 51.0
CMS2_k127_3417277_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 407.0
CMS2_k127_3417277_1 PFAM Histone deacetylase K04768 - - 0.000000000000000000000000000000000000000000000000000000000002515 220.0
CMS2_k127_3417277_2 Evidence 5 No homology to any previously reported sequences K01361,K13277 - 3.4.21.96 0.000000000000000000000000000000000000000009163 161.0
CMS2_k127_3417277_3 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00003602 48.0
CMS2_k127_3427132_0 COG0433 Predicted ATPase - - - 0.00000009526 64.0
CMS2_k127_3428844_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 408.0
CMS2_k127_3428844_1 Pfam:DUF552 K09152 - - 0.00000000000000000000000001703 112.0
CMS2_k127_3434613_0 PFAM PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000004561 226.0
CMS2_k127_3434613_1 PFAM PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000009197 190.0
CMS2_k127_3438550_0 Clostripain family - - - 0.00000000008833 74.0
CMS2_k127_3450885_0 - - - - 0.0000000000004659 78.0
CMS2_k127_3454184_0 Fe-S type, tartrate fumarate subfamily, alpha K01676,K01677,K03779 - 4.2.1.2,4.2.1.32 0.0000000002542 62.0
CMS2_k127_3454184_1 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000234 50.0
CMS2_k127_3457853_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002172 284.0
CMS2_k127_3457853_1 PFAM metal-dependent phosphohydrolase HD sub K06951 - - 0.000000000000000000000001029 108.0
CMS2_k127_3457853_2 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000004667 86.0
CMS2_k127_3457853_3 Transcriptional regulatory protein, C terminal - - - 0.0002104 48.0
CMS2_k127_3482592_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000000000000000000000000000000000001124 247.0
CMS2_k127_3482592_1 Protease prsW family - - - 0.00000000000000003435 89.0
CMS2_k127_3482592_2 Domain of unknown function (DUF4430) - - - 0.00000002709 65.0
CMS2_k127_3503096_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 342.0
CMS2_k127_3503096_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000006833 120.0
CMS2_k127_3503576_0 Periplasmic Protein - - - 0.0000161 54.0
CMS2_k127_3520006_0 Protein of unknown function (DUF1360) - - - 0.00001543 53.0
CMS2_k127_352102_0 Sulphur oxygenase reductase K03151,K16952 - 1.13.11.55,2.8.1.4 0.0000000000000000000000000000000000000000000000004725 181.0
CMS2_k127_352102_1 Circadian clock protein KaiC central region K08482 - - 0.000000000000000000006104 103.0
CMS2_k127_352102_2 Peptidase family C25 - - - 0.000000000006302 78.0
CMS2_k127_352102_3 bacterial-type flagellum-dependent cell motility - - - 0.00008195 55.0
CMS2_k127_3525321_0 phosphoenolpyruvate carboxykinase (GTP) activity K01596,K01610 - 4.1.1.32,4.1.1.49 6.248e-233 736.0
CMS2_k127_3531007_0 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000002755 170.0
CMS2_k127_3531007_1 COG0517 FOG CBS domain - - - 0.00000000000000000000000000499 123.0
CMS2_k127_3531007_2 PFAM Major Facilitator Superfamily - - - 0.0000008862 55.0
CMS2_k127_3531007_3 lycopene cyclase - - - 0.000002636 53.0
CMS2_k127_3535230_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002559 268.0
CMS2_k127_3541969_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008453 332.0
CMS2_k127_3541969_1 PKD domain K19668 - 3.2.1.91 0.00000000000002085 85.0
CMS2_k127_354253_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 439.0
CMS2_k127_354253_1 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000005635 232.0
CMS2_k127_354253_2 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000000000006735 99.0
CMS2_k127_3549645_0 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000000002827 70.0
CMS2_k127_3549645_1 - - - - 0.000003728 54.0
CMS2_k127_3549645_2 Domain of unknown function (DUF4382) - - - 0.0001043 53.0
CMS2_k127_3555415_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001834 241.0
CMS2_k127_3555415_1 RibD C-terminal domain K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000000000005208 203.0
CMS2_k127_3555415_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000001391 155.0
CMS2_k127_3555415_3 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.00000000000000000000000000000005919 126.0
CMS2_k127_3555415_4 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.000000000000000000004043 94.0
CMS2_k127_3555415_5 - - - - 0.000000000000000000007271 104.0
CMS2_k127_3555415_6 - - - - 0.0000000000000007623 86.0
CMS2_k127_3555415_7 Winged helix-turn-helix - - - 0.0004353 44.0
CMS2_k127_3565916_0 - K03561,K12287 - - 0.000000000000000000000000000000000000000002905 172.0
CMS2_k127_3582909_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000003711 221.0
CMS2_k127_3585312_0 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 0.000000000000000000000000000006604 121.0
CMS2_k127_3597223_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 387.0
CMS2_k127_3597223_1 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000001377 245.0
CMS2_k127_3597223_2 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000003951 183.0
CMS2_k127_3597223_3 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000003413 81.0
CMS2_k127_3597223_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000009408 54.0
CMS2_k127_360252_0 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 378.0
CMS2_k127_3606066_0 Domain of unknown function (DUF1768) K09935 - - 0.0000000000000000003175 95.0
CMS2_k127_3606066_1 Sel1-like repeats. K07126 - - 0.00003168 53.0
CMS2_k127_3643820_0 Dehydrogenase K00100,K19955 GO:0003674,GO:0003824,GO:0004022,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 381.0
CMS2_k127_3643820_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000004791 195.0
CMS2_k127_3656201_0 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 445.0
CMS2_k127_3656201_1 TIGRFAM SagB-type dehydrogenase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001397 243.0
CMS2_k127_3656201_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000001593 220.0
CMS2_k127_3656201_3 PFAM type II secretion system K07333 - - 0.0000000000000000000000000006817 130.0
CMS2_k127_3656201_4 PFAM PKD domain containing protein - - - 0.00000000000000001823 93.0
CMS2_k127_3656201_5 PKD domain containing protein - - - 0.0000007311 57.0
CMS2_k127_3656201_6 - - - - 0.000001277 56.0
CMS2_k127_3656201_7 Concanavalin A-like lectin/glucanases superfamily K12287 - - 0.00001485 55.0
CMS2_k127_3657127_0 DNA polymerase K02327 GO:0000228,GO:0000278,GO:0000731,GO:0000781,GO:0000784,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006278,GO:0006281,GO:0006284,GO:0006287,GO:0006289,GO:0006297,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0019439,GO:0022402,GO:0022616,GO:0030894,GO:0031974,GO:0031981,GO:0032991,GO:0032993,GO:0033260,GO:0033554,GO:0033567,GO:0034061,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034655,GO:0042575,GO:0043137,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043596,GO:0043601,GO:0043625,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044786,GO:0045004,GO:0045005,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0061695,GO:0070013,GO:0070914,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0098687,GO:0104004,GO:0140097,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1902296,GO:1902319,GO:1902494,GO:1902969,GO:1902983,GO:1903047,GO:1903459,GO:1904161,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000002353 158.0
CMS2_k127_3659116_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000008293 240.0
CMS2_k127_3659116_1 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000005969 114.0
CMS2_k127_3659116_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.000000000000000002085 89.0
CMS2_k127_3663282_0 P-type ATPase K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 558.0
CMS2_k127_3663282_1 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000003382 234.0
CMS2_k127_3663282_2 Transcriptional regulator, TrmB - - - 0.000000000000000002139 87.0
CMS2_k127_3680422_0 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 323.0
CMS2_k127_3680422_1 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000004243 184.0
CMS2_k127_3714537_0 PFAM PKD domain containing protein - - - 0.000000000000000001411 100.0
CMS2_k127_3714537_1 metallopeptidase activity - - - 0.0000003499 57.0
CMS2_k127_3739229_0 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 424.0
CMS2_k127_3739229_1 Diphthamide K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 293.0
CMS2_k127_3739229_2 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000000000000001689 184.0
CMS2_k127_3739229_3 membrane K09133 - - 0.000000000000007206 83.0
CMS2_k127_3747575_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000007258 221.0
CMS2_k127_3747575_1 - - - - 0.00000000000000000000000000008332 123.0
CMS2_k127_3754887_0 PKD domain containing protein K19355 - 3.2.1.78 0.00000009028 64.0
CMS2_k127_3755530_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 597.0
CMS2_k127_3755530_1 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 391.0
CMS2_k127_3755530_2 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 307.0
CMS2_k127_3755530_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 291.0
CMS2_k127_3755530_4 Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000001455 225.0
CMS2_k127_3755530_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000001239 207.0
CMS2_k127_3755530_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000001542 177.0
CMS2_k127_3755530_7 hydrogenase maturation protease K08315 - 3.4.23.51 0.00000000000000000000000000006755 121.0
CMS2_k127_3755530_8 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000391 105.0
CMS2_k127_37765_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009784 300.0
CMS2_k127_37765_1 Periplasmic copper-binding protein (NosD) K01179 - 3.2.1.4 0.000000000000000000000000000006571 139.0
CMS2_k127_37765_2 Phosphoesterase PA-phosphatase - - - 0.0000000000000004548 83.0
CMS2_k127_37765_3 PFAM PKD domain containing protein - - - 0.0000000000002143 85.0
CMS2_k127_3790899_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 454.0
CMS2_k127_3790899_1 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001157 263.0
CMS2_k127_3790899_2 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000001001 224.0
CMS2_k127_3790899_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000001015 204.0
CMS2_k127_3790899_4 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000000006654 148.0
CMS2_k127_3790899_5 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.00000000000005313 75.0
CMS2_k127_3812151_0 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000000000000000000000003274 210.0
CMS2_k127_3812151_1 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000001188 136.0
CMS2_k127_3812151_2 Acyl-protein synthetase, LuxE - - - 0.000000000002818 69.0
CMS2_k127_3812151_3 Aminotransferase, class V - - - 0.000000001077 60.0
CMS2_k127_3844416_0 SOCE-associated regulatory factor of calcium homoeostasis - - - 0.0000000003778 72.0
CMS2_k127_3844811_0 Belongs to the V-ATPase 116 kDa subunit family K02123 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006885,GO:0007035,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019725,GO:0019829,GO:0019899,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0045851,GO:0046034,GO:0046390,GO:0046483,GO:0046961,GO:0048878,GO:0050801,GO:0051117,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0055086,GO:0065007,GO:0065008,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 307.0
CMS2_k127_3844811_1 subunit K K02124 - - 0.0000000000000000000003964 103.0
CMS2_k127_3844811_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000006708 82.0
CMS2_k127_3844811_3 4Fe-4S dicluster domain K03390,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000002261 74.0
CMS2_k127_3844811_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00003056 54.0
CMS2_k127_3847488_0 Sodium/hydrogen exchanger family - - - 0.0008566 51.0
CMS2_k127_3855252_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 409.0
CMS2_k127_3855252_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 296.0
CMS2_k127_3855252_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000001599 170.0
CMS2_k127_3855252_11 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000008371 170.0
CMS2_k127_3855252_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000006414 165.0
CMS2_k127_3855252_13 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000003023 163.0
CMS2_k127_3855252_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000005314 148.0
CMS2_k127_3855252_15 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000007642 145.0
CMS2_k127_3855252_16 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000004762 142.0
CMS2_k127_3855252_17 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000002621 136.0
CMS2_k127_3855252_18 PFAM ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000002155 110.0
CMS2_k127_3855252_19 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000005642 113.0
CMS2_k127_3855252_2 ABC-type phosphate transport system, periplasmic component K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 290.0
CMS2_k127_3855252_20 Ribosomal L29 protein K02904 - - 0.000000000000000001644 86.0
CMS2_k127_3855252_21 ribosomal protein S14 K02954 - - 0.00000000000000000362 84.0
CMS2_k127_3855252_22 Ribosomal protein L23 K02892 - - 0.00000000000000001249 85.0
CMS2_k127_3855252_23 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.0000000003685 64.0
CMS2_k127_3855252_24 COG NOG33517 non supervised orthologous group - - - 0.0000002962 58.0
CMS2_k127_3855252_25 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000004201 57.0
CMS2_k127_3855252_26 Winged helix-turn-helix domain (DUF2582) - - - 0.000008735 54.0
CMS2_k127_3855252_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001443 271.0
CMS2_k127_3855252_4 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007967 259.0
CMS2_k127_3855252_5 ribosomal protein S3 K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003925 259.0
CMS2_k127_3855252_6 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000000000000000000000000000000000000000000000009594 223.0
CMS2_k127_3855252_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000004546 195.0
CMS2_k127_3855252_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000001855 182.0
CMS2_k127_3855252_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000005169 178.0
CMS2_k127_3865005_0 aminopeptidase K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 326.0
CMS2_k127_3865005_1 Lrp/AsnC ligand binding domain - - - 0.00000007001 59.0
CMS2_k127_3865005_2 helix_turn_helix ASNC type K03719 - - 0.000003682 55.0
CMS2_k127_3915107_0 TRAF-like signal transducer - - - 0.0000007834 58.0
CMS2_k127_3915107_1 activation of NF-kappaB-inducing kinase activity K03174,K09848,K09849 - - 0.0008696 50.0
CMS2_k127_3923933_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 423.0
CMS2_k127_3923933_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 353.0
CMS2_k127_3923933_2 - - - - 0.000000000000000000000000196 110.0
CMS2_k127_3923933_3 Carbohydrate kinase - - - 0.00001716 56.0
CMS2_k127_3938975_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 479.0
CMS2_k127_3938975_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000003362 156.0
CMS2_k127_3938975_2 response regulator, receiver K07668,K07669 - - 0.000000000000000000000000000000003213 132.0
CMS2_k127_3939567_0 Ras-related protein RABC2a-like K07910 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005794,GO:0008092,GO:0012505,GO:0017022,GO:0030742,GO:0032029,GO:0032036,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0080115 - 0.000000000002021 73.0
CMS2_k127_3944658_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 387.0
CMS2_k127_3944658_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 305.0
CMS2_k127_3944658_2 - - - - 0.00000000000002276 79.0
CMS2_k127_3947536_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000002137 94.0
CMS2_k127_3947536_1 Methyltransferase domain - - - 0.0001728 51.0
CMS2_k127_3990402_0 radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 308.0
CMS2_k127_3990402_1 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000003264 216.0
CMS2_k127_3990402_2 transferase activity, transferring glycosyl groups K20742 - 3.4.14.13 0.0000000000000000000000000000000000000000000000000000000002059 210.0
CMS2_k127_3990402_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000001195 70.0
CMS2_k127_3990876_0 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.0000000000000000000000000000002258 126.0
CMS2_k127_3990876_1 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000000000004913 100.0
CMS2_k127_3993635_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000008182 246.0
CMS2_k127_3993635_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000001163 212.0
CMS2_k127_3999474_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 321.0
CMS2_k127_3999474_1 Propeptide_C25 - - - 0.000000000000001322 91.0
CMS2_k127_3999474_2 Propeptide_C25 - - - 0.00000000000009886 85.0
CMS2_k127_3999474_3 pectinesterase activity K01051,K10297 - 3.1.1.11 0.0000000002142 74.0
CMS2_k127_3999474_4 PFAM TPR repeat-containing protein - - - 0.0000000002552 73.0
CMS2_k127_3999474_5 Nitrous oxidase accessory protein - - - 0.0000008627 58.0
CMS2_k127_4017642_0 ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues K01648 GO:0000166,GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003878,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006066,GO:0006082,GO:0006084,GO:0006085,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009893,GO:0009987,GO:0012505,GO:0015936,GO:0016020,GO:0016053,GO:0016125,GO:0016126,GO:0016192,GO:0016740,GO:0016746,GO:0016999,GO:0017076,GO:0017144,GO:0018130,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030141,GO:0030554,GO:0031323,GO:0031325,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032940,GO:0032991,GO:0033500,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0034774,GO:0035337,GO:0035383,GO:0035384,GO:0035578,GO:0035639,GO:0036094,GO:0036230,GO:0042119,GO:0042582,GO:0042592,GO:0042593,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046165,GO:0046390,GO:0046394,GO:0046483,GO:0046903,GO:0046912,GO:0046949,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0055086,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901568,GO:1901570,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653,GO:1904813 2.3.3.8 7.562e-257 804.0
CMS2_k127_4017642_1 ATP citrate synthase activity K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 547.0
CMS2_k127_4017642_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 383.0
CMS2_k127_4017642_3 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 323.0
CMS2_k127_4017642_4 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000001124 123.0
CMS2_k127_4039071_0 Belongs to the protein kinase superfamily. Ser Thr protein kinase family - - - 0.0002286 54.0
CMS2_k127_4041944_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000005274 133.0
CMS2_k127_4041944_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000009904 81.0
CMS2_k127_4041944_2 Ribosomal protein L30p/L7e K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000003281 76.0
CMS2_k127_4046562_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 464.0
CMS2_k127_4046562_1 Peptidase family C25 - - - 0.000000000002384 78.0
CMS2_k127_4049229_0 - K03741 - 1.20.4.1 0.0000000000006471 73.0
CMS2_k127_4049229_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000002138 66.0
CMS2_k127_4049229_2 self proteolysis - - - 0.00000004623 66.0
CMS2_k127_4056195_0 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 524.0
CMS2_k127_4056195_1 AAA-like domain K06915 - - 0.000000000000000000000000000000000003255 142.0
CMS2_k127_4081178_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 3.951e-312 970.0
CMS2_k127_4081178_1 PFAM CoA-binding domain protein K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 361.0
CMS2_k127_4081178_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000138 205.0
CMS2_k127_4081178_3 PFAM Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000006976 186.0
CMS2_k127_4081178_4 PFAM NMD3 family K07562 - - 0.00000000000000000000000000000000000000000002843 174.0
CMS2_k127_4081178_5 Transposase IS200 like K07491 - - 0.0008459 49.0
CMS2_k127_4084651_0 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000002348 150.0
CMS2_k127_4084651_1 Domain of unknown function (DUF4870) - - - 0.0000000000000000000004817 99.0
CMS2_k127_4084651_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0002741 50.0
CMS2_k127_4086104_0 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.0000000000000000000000000000000004874 139.0
CMS2_k127_4086104_1 aminopeptidase activity K05994 - 3.4.11.10 0.00000000000000000000001384 112.0
CMS2_k127_4086104_2 FlgD Ig-like domain - - - 0.0000006057 59.0
CMS2_k127_4101079_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 326.0
CMS2_k127_4101079_1 Membrane protein of unknown function DUF63 - - - 0.0000001976 62.0
CMS2_k127_4104599_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 477.0
CMS2_k127_4104599_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000006398 214.0
CMS2_k127_4104599_2 Cold shock protein domain K03704 - - 0.0000000000000001748 80.0
CMS2_k127_4104599_3 acid phosphatase activity K22390 - - 0.00000000118 69.0
CMS2_k127_4112753_0 amino acid activation for nonribosomal peptide biosynthetic process K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000003994 192.0
CMS2_k127_4112753_1 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.000000000000000000000000000002681 138.0
CMS2_k127_4112753_2 Papain family cysteine protease - - - 0.00000000000000000001225 104.0
CMS2_k127_4112753_3 PQQ-like domain - - - 0.00000000000000004859 96.0
CMS2_k127_4112753_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000001884 83.0
CMS2_k127_4112753_5 Transglutaminase-like superfamily - - - 0.000000002977 67.0
CMS2_k127_4115529_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000005115 205.0
CMS2_k127_4115529_1 Pkd domain containing protein - - - 0.0003245 49.0
CMS2_k127_4116500_0 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000307 210.0
CMS2_k127_4116500_1 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000002231 159.0
CMS2_k127_4120174_0 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000001606 166.0
CMS2_k127_412469_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 498.0
CMS2_k127_412469_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 315.0
CMS2_k127_412469_2 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000009282 266.0
CMS2_k127_412469_3 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000003346 255.0
CMS2_k127_412469_4 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000004968 220.0
CMS2_k127_412469_5 methylase K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000000000008118 193.0
CMS2_k127_412469_6 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000005764 188.0
CMS2_k127_412469_7 S-layer protein - - - 0.00001131 57.0
CMS2_k127_4132550_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000003245 197.0
CMS2_k127_4132550_1 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.000000000007362 75.0
CMS2_k127_4132550_2 CAAX amino terminal protease family K07052 - - 0.000001491 59.0
CMS2_k127_4138507_0 transferase activity, transferring acyl groups - GO:0005575,GO:0016020 - 0.0000008934 60.0
CMS2_k127_4138507_1 Belongs to the small GTPase superfamily. SAR1 family K07953 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005798,GO:0006810,GO:0006888,GO:0006900,GO:0006996,GO:0008150,GO:0009987,GO:0012505,GO:0012506,GO:0012507,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0022607,GO:0030117,GO:0030120,GO:0030127,GO:0030133,GO:0030134,GO:0030135,GO:0030658,GO:0030659,GO:0030660,GO:0030662,GO:0031090,GO:0031410,GO:0031982,GO:0032991,GO:0034622,GO:0035459,GO:0043226,GO:0043227,GO:0043229,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0046907,GO:0048193,GO:0048194,GO:0048475,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051668,GO:0061024,GO:0065003,GO:0071840,GO:0090110,GO:0090114,GO:0097708,GO:0098588,GO:0098796,GO:0098805 - 0.00003186 46.0
CMS2_k127_4148843_0 piggyBac transposable element derived 4 - - - 0.000001323 57.0
CMS2_k127_4159320_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000001972 227.0
CMS2_k127_4159320_1 PQQ enzyme repeat - - - 0.00000000000000000000000000000000000000000000000000000000000007116 225.0
CMS2_k127_4161919_0 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000002598 185.0
CMS2_k127_4161919_1 Type II secretion system (T2SS), protein F K07333 - - 0.000000000000000000000002609 105.0
CMS2_k127_4161919_2 PKD domain containing protein - - - 0.0002947 52.0
CMS2_k127_4174591_0 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000001846 181.0
CMS2_k127_4174591_1 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000000002479 113.0
CMS2_k127_4174591_2 Thiamine-binding protein - - - 0.0000000000000775 76.0
CMS2_k127_4184726_0 GatB/GatE catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 415.0
CMS2_k127_4184726_1 Psort location Cytoplasmic, score K01424 - 3.5.1.1 0.000000000002683 71.0
CMS2_k127_4194199_1 ERCC4 domain protein K10848 - - 0.00000183 58.0
CMS2_k127_4210002_0 - - - - 0.000000003534 68.0
CMS2_k127_4236439_0 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000003014 128.0
CMS2_k127_4236439_1 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000123 111.0
CMS2_k127_4236439_2 PFAM periplasmic copper-binding - - - 0.00006689 49.0
CMS2_k127_4254121_0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.000000000000000004976 89.0
CMS2_k127_4254121_1 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.00000000000002371 85.0
CMS2_k127_4254239_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 473.0
CMS2_k127_4254239_1 SMART Excinuclease ABC, C subunit - - - 0.0000000000000000000000000000000001145 136.0
CMS2_k127_4254239_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.0000000000000000000003573 98.0
CMS2_k127_4254239_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives - - - 0.0000000000000001119 84.0
CMS2_k127_4271874_0 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001671 314.0
CMS2_k127_4271874_1 PFAM Fibronectin type III domain - - - 0.000000000000000000000000000000000000000001752 182.0
CMS2_k127_4271874_2 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000001823 124.0
CMS2_k127_4271874_3 Domain of unknown function (DU1801) - - - 0.00000000000003598 73.0
CMS2_k127_4285799_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 576.0
CMS2_k127_4285799_1 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 577.0
CMS2_k127_4285799_10 Amino acid permease - - - 0.000000000000006196 76.0
CMS2_k127_4285799_11 - - - - 0.0000000000008957 71.0
CMS2_k127_4285799_12 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000005049 54.0
CMS2_k127_4285799_2 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 527.0
CMS2_k127_4285799_3 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 476.0
CMS2_k127_4285799_4 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 404.0
CMS2_k127_4285799_5 Phosphopantothenate/pantothenate synthetase K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000277 267.0
CMS2_k127_4285799_6 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000569 224.0
CMS2_k127_4285799_7 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000001345 177.0
CMS2_k127_4285799_8 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000283 166.0
CMS2_k127_4285799_9 - - - - 0.000000000000000000000406 99.0
CMS2_k127_4290802_0 Putative molybdenum carrier - - - 0.0000000000006127 77.0
CMS2_k127_4302104_0 PQQ enzyme repeat - - - 0.000000000000005831 85.0
CMS2_k127_4302104_1 Expressed protein - - - 0.0009318 47.0
CMS2_k127_4318016_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000004922 207.0
CMS2_k127_4318016_1 GTP cyclohydrolase II K01497,K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000004691 158.0
CMS2_k127_4365324_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000001142 156.0
CMS2_k127_4365324_1 Sugar (and other) transporter - - - 0.0001502 50.0
CMS2_k127_4373012_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 591.0
CMS2_k127_4373012_1 Belongs to the archaeal adenylate kinase family K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000003061 191.0
CMS2_k127_4379235_0 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000004179 218.0
CMS2_k127_4379235_1 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000000000000000000000001919 202.0
CMS2_k127_4379235_2 acid phosphatase activity - - - 0.0000004407 63.0
CMS2_k127_4383816_0 COG1520 FOG WD40-like repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 302.0
CMS2_k127_4384746_0 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000003692 190.0
CMS2_k127_4384746_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.000000000000000000000000000000000000001315 161.0
CMS2_k127_4384746_2 GPR1 FUN34 yaaH family protein K07034 - - 0.00000002883 59.0
CMS2_k127_4387430_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000006601 231.0
CMS2_k127_4399100_0 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 422.0
CMS2_k127_4399100_1 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000009867 159.0
CMS2_k127_4399100_2 Type II secretion system K07333 - - 0.00000000000000000000000000000001959 137.0
CMS2_k127_4399100_3 Concanavalin A-like lectin/glucanases superfamily K12287 - - 0.000005885 57.0
CMS2_k127_4414462_0 4Fe-4S dicluster domain K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001853 287.0
CMS2_k127_4414462_1 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003404 280.0
CMS2_k127_4414462_2 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006401 243.0
CMS2_k127_4414462_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000002008 124.0
CMS2_k127_4414462_4 PFAM DRTGG domain - - - 0.000000000000000000000001388 107.0
CMS2_k127_4415803_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 2.359e-254 793.0
CMS2_k127_4415803_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 1.525e-245 766.0
CMS2_k127_4415803_2 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 486.0
CMS2_k127_4415803_3 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000009282 192.0
CMS2_k127_4415803_4 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 0.000000000003694 73.0
CMS2_k127_4433959_0 self proteolysis - - - 0.0000000000147 76.0
CMS2_k127_4433959_1 cell wall organization - - - 0.0006493 49.0
CMS2_k127_4450298_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000005417 148.0
CMS2_k127_4450298_1 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.00000000003046 74.0
CMS2_k127_4450298_2 Lrp/AsnC ligand binding domain - - - 0.00000000007693 63.0
CMS2_k127_4450298_3 Protein of unknown function, DUF599 - - - 0.000004655 57.0
CMS2_k127_4455912_0 PA14 domain - - - 0.0000000000000002842 90.0
CMS2_k127_4460153_0 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000001417 200.0
CMS2_k127_4460153_1 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000003962 183.0
CMS2_k127_4482126_0 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 443.0
CMS2_k127_4482126_1 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000002253 235.0
CMS2_k127_4482126_2 Haloacid dehalogenase-like hydrolase K01838 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009292,GO:0009294,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0033554,GO:0042221,GO:0043167,GO:0043169,GO:0044238,GO:0044764,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704 5.4.2.6 0.0000000000000008517 81.0
CMS2_k127_4482126_3 PRC-barrel domain - - - 0.0000002606 56.0
CMS2_k127_4494523_0 Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand K03165 GO:0000002,GO:0000003,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006260,GO:0006265,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007005,GO:0007049,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009611,GO:0009888,GO:0009987,GO:0016043,GO:0016604,GO:0016605,GO:0016853,GO:0022414,GO:0031099,GO:0031974,GO:0031981,GO:0032502,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0042060,GO:0042246,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048589,GO:0048856,GO:0050896,GO:0051276,GO:0051321,GO:0051716,GO:0070013,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901576 5.99.1.2 0.000000008694 59.0
CMS2_k127_4496974_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 514.0
CMS2_k127_4496974_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.000000000000000000000000000000000000000000000003074 180.0
CMS2_k127_4496974_2 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000002063 139.0
CMS2_k127_4496974_3 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.000000000000000000003739 103.0
CMS2_k127_4496974_4 PD-(D/E)XK nuclease superfamily K10742 - 3.6.4.12 0.0002964 44.0
CMS2_k127_4520898_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004694 265.0
CMS2_k127_4520898_1 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000003004 245.0
CMS2_k127_4520898_2 ATPases associated with a variety of cellular activities K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000004579 218.0
CMS2_k127_4538635_0 DNA polymerase K02337 - 2.7.7.7 0.0000000000000000000000000000002733 136.0
CMS2_k127_4538635_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000007406 90.0
CMS2_k127_4538635_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316,K17680 - 3.6.4.12 0.00000001374 62.0
CMS2_k127_4539294_0 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.000000000000000000000000000000000000000000000000000001706 196.0
CMS2_k127_4539294_1 Peptidase family M50 - - - 0.000000000000000006088 91.0
CMS2_k127_4539294_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000001132 60.0
CMS2_k127_4548547_0 - - - - 0.000000000000000000001882 101.0
CMS2_k127_4555949_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000005429 218.0
CMS2_k127_4566323_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 395.0
CMS2_k127_4584123_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 364.0
CMS2_k127_4584123_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000004479 237.0
CMS2_k127_4584123_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000004658 157.0
CMS2_k127_4584123_3 Caspase domain - - - 0.00009891 54.0
CMS2_k127_4584123_4 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0005382 51.0
CMS2_k127_4588171_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 493.0
CMS2_k127_4588171_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000002851 245.0
CMS2_k127_4588171_2 SMART Peptidase A22, presenilin signal peptide - - - 0.00000000000000000000000000000000000000000000000000000000000009297 224.0
CMS2_k127_4588171_3 Zinc metalloprotease (Elastase) - - - 0.000000000000003982 88.0
CMS2_k127_4602465_0 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 382.0
CMS2_k127_4602465_1 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 339.0
CMS2_k127_4602465_10 tail collar domain protein - - - 0.0000000000005036 74.0
CMS2_k127_4602465_11 tail collar domain protein - - - 0.000000000001976 78.0
CMS2_k127_4602465_12 Phage minor structural protein GP20 - - - 0.000000000002115 74.0
CMS2_k127_4602465_13 - - - - 0.000000000003896 71.0
CMS2_k127_4602465_14 Psort location Cytoplasmic, score - - - 0.000000001006 65.0
CMS2_k127_4602465_15 - - - - 0.000000001229 68.0
CMS2_k127_4602465_16 Glycosyl hydrolases family 25 - - - 0.0000000264 65.0
CMS2_k127_4602465_17 COG2931 RTX toxins and related Ca2 -binding proteins K01406,K07004 - 3.4.24.40 0.00000004178 67.0
CMS2_k127_4602465_19 - - - - 0.00001102 52.0
CMS2_k127_4602465_2 tape measure K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 319.0
CMS2_k127_4602465_20 Septum formation - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0006341 44.0
CMS2_k127_4602465_21 domain, Protein - - - 0.0006502 51.0
CMS2_k127_4602465_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000481 271.0
CMS2_k127_4602465_4 - - - - 0.0000000000000000000000000000000000000000000000000000009583 196.0
CMS2_k127_4602465_5 Bacteriophage Gp15 protein - - - 0.0000000000000000000000000000000000000000003394 165.0
CMS2_k127_4602465_6 - - - - 0.00000000000000000000000000000000000002956 151.0
CMS2_k127_4602465_7 - - - - 0.0000000000000000000000000000000000005663 156.0
CMS2_k127_4602465_9 - - - - 0.0000000000000000000000000001411 119.0
CMS2_k127_46124_0 primase small subunit K02684,K16733 GO:0000082,GO:0000228,GO:0000278,GO:0000428,GO:0000723,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005657,GO:0005658,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019725,GO:0022402,GO:0030880,GO:0030894,GO:0031974,GO:0031981,GO:0032200,GO:0032201,GO:0032774,GO:0032991,GO:0032993,GO:0033260,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043596,GO:0043601,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044770,GO:0044772,GO:0044786,GO:0044843,GO:0046483,GO:0051276,GO:0055029,GO:0060249,GO:0061695,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0097159,GO:0097747,GO:0140097,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1903047,GO:1990234 - 0.000000000000004917 88.0
CMS2_k127_46124_1 CHY zinc finger K16276 GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009057,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010498,GO:0016567,GO:0016740,GO:0019538,GO:0019725,GO:0019787,GO:0019941,GO:0030003,GO:0030163,GO:0031667,GO:0031668,GO:0031669,GO:0032446,GO:0033554,GO:0036211,GO:0042592,GO:0042594,GO:0043161,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051603,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0061630,GO:0061659,GO:0065007,GO:0065008,GO:0070647,GO:0071496,GO:0071704,GO:0098771,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0002702 53.0
CMS2_k127_46124_2 Ulp1 protease family, C-terminal catalytic domain K08597 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0019783,GO:0019784,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.68 0.0009062 51.0
CMS2_k127_4630268_0 Serine threonine-protein kinase K08819 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004693,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051726,GO:0065007,GO:0071704,GO:0071944,GO:0097472,GO:0140096,GO:1901564 2.7.11.22,2.7.11.23 0.00000000000000000003595 104.0
CMS2_k127_4637538_0 - - - - 0.000000000000001327 87.0
CMS2_k127_4637538_1 Leucine-rich repeats, typical (most populated) subfamily - - - 0.000331 52.0
CMS2_k127_4658578_0 oxidoreductase activity K02396 - - 0.00000000004708 76.0
CMS2_k127_4658578_1 Integrin alpha (beta-propellor repeats). - - - 0.000003111 60.0
CMS2_k127_4658578_2 PKD domain containing protein - - - 0.00001061 54.0
CMS2_k127_4676741_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 477.0
CMS2_k127_4676741_1 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000001403 170.0
CMS2_k127_4676741_2 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000000000000000000000000000000002653 148.0
CMS2_k127_4703764_0 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007406 284.0
CMS2_k127_4703764_1 - K03561,K12287 - - 0.00000000000000000000000000000000000000000003629 179.0
CMS2_k127_4703764_2 methyltransferase activity - - - 0.00000000000007745 74.0
CMS2_k127_4720402_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000004427 213.0
CMS2_k127_4722961_0 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 409.0
CMS2_k127_4722961_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 389.0
CMS2_k127_4722961_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009936 298.0
CMS2_k127_4722961_3 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000001354 118.0
CMS2_k127_4722961_4 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000001628 92.0
CMS2_k127_4722961_5 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000005562 72.0
CMS2_k127_4724013_0 PFAM Radical SAM domain protein K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 332.0
CMS2_k127_4724013_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000001048 156.0
CMS2_k127_4737282_0 FAD binding domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 491.0
CMS2_k127_4737282_1 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 335.0
CMS2_k127_4737282_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 310.0
CMS2_k127_4737282_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004285 282.0
CMS2_k127_4737282_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008973 264.0
CMS2_k127_4737282_5 Thioredoxin K03671 - - 0.0000000000000000000000000000001091 127.0
CMS2_k127_4737282_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000002272 77.0
CMS2_k127_4757554_0 metallopeptidase activity - - - 0.0000001055 62.0
CMS2_k127_4788969_0 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000002052 237.0
CMS2_k127_4788969_1 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.000000000000000000000000000000002686 134.0
CMS2_k127_4788969_2 - - - - 0.000000000000159 74.0
CMS2_k127_4788969_3 Glycoside hydrolase family 28 - - - 0.000002118 58.0
CMS2_k127_4811579_0 ATP-dependent DNA helicase activity - - - 0.000000001045 70.0
CMS2_k127_482123_0 Belongs to the peptidase C1 family K01275 GO:0000323,GO:0001775,GO:0001906,GO:0001909,GO:0001913,GO:0002250,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002449,GO:0002456,GO:0002460,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0005793,GO:0005794,GO:0005798,GO:0005813,GO:0005815,GO:0005856,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006888,GO:0006900,GO:0006901,GO:0006903,GO:0006915,GO:0006955,GO:0006996,GO:0007568,GO:0008047,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008234,GO:0008236,GO:0009056,GO:0009057,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010467,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010952,GO:0012501,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0016485,GO:0016504,GO:0016505,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0019899,GO:0019902,GO:0022607,GO:0023051,GO:0023056,GO:0030134,GO:0030135,GO:0030141,GO:0030162,GO:0030163,GO:0030234,GO:0031090,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031404,GO:0031410,GO:0031638,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032268,GO:0032270,GO:0032502,GO:0032940,GO:0033116,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042176,GO:0042221,GO:0042582,GO:0042802,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043621,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045732,GO:0045862,GO:0046903,GO:0046907,GO:0048193,GO:0048194,GO:0048199,GO:0048207,GO:0048208,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051087,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051603,GO:0051604,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0052547,GO:0060205,GO:0060255,GO:0061024,GO:0061134,GO:0065003,GO:0065007,GO:0065009,GO:0070011,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0090114,GO:0097708,GO:0098588,GO:0098772,GO:0099503,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:2001233,GO:2001235 3.4.14.1 0.00000000000000000000000000000000005158 151.0
CMS2_k127_482123_2 COG1404 Subtilisin-like serine proteases K14645 GO:0005575,GO:0005576 - 0.0000000000000495 85.0
CMS2_k127_482123_3 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.00000000001256 78.0
CMS2_k127_482123_4 PFAM Nitroreductase - - - 0.00000000002537 77.0
CMS2_k127_482123_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000003206 63.0
CMS2_k127_483255_0 thymidine kinase K00857 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004683,GO:0004797,GO:0005488,GO:0005515,GO:0005516,GO:0005524,GO:0006139,GO:0006213,GO:0006259,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019538,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046104,GO:0046125,GO:0046483,GO:0046983,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140096,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000002007 186.0
CMS2_k127_4840531_0 DNA primase K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 416.0
CMS2_k127_4840531_1 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000000009509 109.0
CMS2_k127_4840531_2 Uncharacterised protein family UPF0058 - - - 0.0000000001515 66.0
CMS2_k127_4854337_0 PQQ-like domain - - - 0.00000000000000000000000004871 123.0
CMS2_k127_4856129_0 - - - - 0.0001037 51.0
CMS2_k127_4873318_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.55e-210 686.0
CMS2_k127_4873318_1 tRNA binding K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 498.0
CMS2_k127_4873318_2 MiaB-like tRNA modifying enzyme, archaeal-type K15865 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 352.0
CMS2_k127_4873318_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002837 278.0
CMS2_k127_4873318_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000002344 199.0
CMS2_k127_4873318_5 but it may be involved in stabilization of the trimeric complex - - - 0.0000001772 54.0
CMS2_k127_4887629_0 Zinc ion binding K04725,K16060,K16061 GO:0000003,GO:0000165,GO:0000187,GO:0000209,GO:0000803,GO:0001666,GO:0001741,GO:0001817,GO:0001890,GO:0001932,GO:0001934,GO:0001959,GO:0002020,GO:0002225,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002813,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003006,GO:0003674,GO:0003712,GO:0003713,GO:0003824,GO:0004842,GO:0004857,GO:0004866,GO:0004869,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005794,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006508,GO:0006511,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006963,GO:0006964,GO:0007154,GO:0007165,GO:0007166,GO:0007249,GO:0007254,GO:0007257,GO:0007275,GO:0007423,GO:0008150,GO:0008152,GO:0008219,GO:0008270,GO:0009056,GO:0009057,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009898,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010498,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0010803,GO:0010939,GO:0010941,GO:0010951,GO:0010955,GO:0012501,GO:0012505,GO:0015630,GO:0016020,GO:0016021,GO:0016043,GO:0016310,GO:0016567,GO:0016579,GO:0016740,GO:0019219,GO:0019220,GO:0019221,GO:0019222,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0022414,GO:0022416,GO:0022607,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0030162,GO:0030163,GO:0030234,GO:0030414,GO:0031098,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031333,GO:0031347,GO:0031349,GO:0031396,GO:0031398,GO:0031399,GO:0031401,GO:0031625,GO:0031974,GO:0031981,GO:0032101,GO:0032103,GO:0032147,GO:0032182,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032388,GO:0032446,GO:0032501,GO:0032502,GO:0032872,GO:0032874,GO:0032879,GO:0032880,GO:0032991,GO:0033157,GO:0033158,GO:0033160,GO:0033209,GO:0033554,GO:0033674,GO:0034097,GO:0034121,GO:0034248,GO:0034250,GO:0034612,GO:0035556,GO:0035631,GO:0036211,GO:0036293,GO:0038061,GO:0039531,GO:0039535,GO:0042127,GO:0042221,GO:0042306,GO:0042307,GO:0042325,GO:0042326,GO:0042327,GO:0042742,GO:0042802,GO:0042981,GO:0043027,GO:0043028,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043086,GO:0043122,GO:0043123,GO:0043130,GO:0043154,GO:0043161,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043235,GO:0043254,GO:0043281,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043506,GO:0043507,GO:0043549,GO:0043632,GO:0043900,GO:0043902,GO:0043933,GO:0044085,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045088,GO:0045121,GO:0045595,GO:0045859,GO:0045860,GO:0045861,GO:0045935,GO:0045936,GO:0045937,GO:0046328,GO:0046330,GO:0046822,GO:0046824,GO:0046872,GO:0046914,GO:0047485,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048608,GO:0048731,GO:0048856,GO:0050688,GO:0050727,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050829,GO:0050896,GO:0051049,GO:0051050,GO:0051087,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051222,GO:0051223,GO:0051239,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051291,GO:0051336,GO:0051338,GO:0051346,GO:0051347,GO:0051403,GO:0051603,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0051865,GO:0052547,GO:0052548,GO:0060255,GO:0060341,GO:0060544,GO:0060546,GO:0060547,GO:0060548,GO:0060759,GO:0061057,GO:0061134,GO:0061135,GO:0061458,GO:0061630,GO:0061659,GO:0061945,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070228,GO:0070247,GO:0070265,GO:0070266,GO:0070302,GO:0070304,GO:0070424,GO:0070482,GO:0070534,GO:0070613,GO:0070646,GO:0070647,GO:0070887,GO:0070936,GO:0071310,GO:0071345,GO:0071356,GO:0071704,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0089720,GO:0090087,GO:0090316,GO:0097300,GO:0097340,GO:0097341,GO:0098542,GO:0098552,GO:0098562,GO:0098589,GO:0098770,GO:0098772,GO:0098796,GO:0098797,GO:0098802,GO:0098805,GO:0098857,GO:0140096,GO:0140110,GO:1900044,GO:1900180,GO:1900182,GO:1900424,GO:1900426,GO:1901222,GO:1901564,GO:1901565,GO:1901575,GO:1902442,GO:1902443,GO:1902523,GO:1902524,GO:1902525,GO:1902527,GO:1902531,GO:1902533,GO:1902680,GO:1902914,GO:1902916,GO:1903317,GO:1903318,GO:1903320,GO:1903322,GO:1903506,GO:1903508,GO:1903827,GO:1903829,GO:1904589,GO:1904591,GO:1904951,GO:1990001,GO:2000106,GO:2000116,GO:2000117,GO:2000377,GO:2000378,GO:2001141 2.3.2.27 0.00000271 57.0
CMS2_k127_4888709_0 Sulfotransferase family - - - 0.0009338 49.0
CMS2_k127_4898359_0 RHS Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001404 269.0
CMS2_k127_489944_0 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000000905 216.0
CMS2_k127_489944_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000003739 163.0
CMS2_k127_4905974_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 9.28e-263 820.0
CMS2_k127_4905974_1 PFAM Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 402.0
CMS2_k127_4905974_2 - K00960 - 2.7.7.6 0.000000000000002652 83.0
CMS2_k127_4905974_3 PFAM Forkhead-associated protein - - - 0.000000006351 66.0
CMS2_k127_4905974_4 metabolite transporter - - - 0.0000002415 57.0
CMS2_k127_4910232_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000004421 224.0
CMS2_k127_4910232_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000001517 222.0
CMS2_k127_4910232_2 - - - - 0.0000000000000002236 87.0
CMS2_k127_4917266_0 aconitate hydratase K01681 - 4.2.1.3 1.488e-289 900.0
CMS2_k127_4917266_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000137 227.0
CMS2_k127_4917266_2 COG1522 Transcriptional regulators - - - 0.000000000000000000000000004753 124.0
CMS2_k127_4925169_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 604.0
CMS2_k127_4925169_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 341.0
CMS2_k127_4925169_2 Pyruvate phosphate dikinase, PEP pyruvate binding domain - - - 0.0000000002397 63.0
CMS2_k127_4931617_0 - - - - 0.00000000000000000000000000004925 128.0
CMS2_k127_4931617_1 - - - - 0.0000002739 63.0
CMS2_k127_4936046_0 - - - - 0.0000000000000001005 82.0
CMS2_k127_4956745_0 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000001468 260.0
CMS2_k127_4961324_0 agmatine deiminase activity K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 516.0
CMS2_k127_4961324_1 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 396.0
CMS2_k127_4961324_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 342.0
CMS2_k127_4961324_3 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 320.0
CMS2_k127_4961324_4 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.00000000000000000000000000000000000000000000000000000007649 202.0
CMS2_k127_4961324_5 Domain of unknown function (DUF4314) - - - 0.0000000118 59.0
CMS2_k127_4961324_6 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000003474 55.0
CMS2_k127_4964102_0 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 379.0
CMS2_k127_4964102_1 PKD domain K19668 - 3.2.1.91 0.00000000000000001007 96.0
CMS2_k127_4964102_2 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000000000002526 82.0
CMS2_k127_4993372_0 LVIVD repeat-containing protein - - - 0.000000000000000000000001426 116.0
CMS2_k127_4993372_1 Domain of unknown function (DUF1735) - - - 0.0000004209 55.0
CMS2_k127_4999994_0 Peptidase family C25 - - - 0.0000008954 62.0
CMS2_k127_5005894_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009596 509.0
CMS2_k127_5005894_1 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000008667 137.0
CMS2_k127_5014870_0 Putative exonuclease SbcCD, C subunit K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 356.0
CMS2_k127_5014870_1 GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 299.0
CMS2_k127_5014870_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.0000000000000001415 86.0
CMS2_k127_5075215_0 Xeroderma pigmentosum G N-region K10746 - - 0.0000000009958 71.0
CMS2_k127_5075980_0 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 465.0
CMS2_k127_5075980_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000002018 186.0
CMS2_k127_5075980_2 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000001693 148.0
CMS2_k127_5075980_3 PFAM Citrate lyase, alpha subunit K01643 - 2.8.3.10 0.000000000000000003523 87.0
CMS2_k127_5075980_4 Lipocalin-like domain - - - 0.0000000276 66.0
CMS2_k127_5088538_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000003801 175.0
CMS2_k127_5088538_1 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.00000000000000000000000000008754 125.0
CMS2_k127_5088538_2 Transcriptional regulator - - - 0.000000000000000001534 95.0
CMS2_k127_5094253_0 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.000000000000000000000000000000000008528 155.0
CMS2_k127_5094253_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000001333 68.0
CMS2_k127_5094253_2 Nitrous oxidase accessory protein K07218 - - 0.000000003352 70.0
CMS2_k127_5094253_3 COG1522 Transcriptional regulators K03719 - - 0.0000002794 62.0
CMS2_k127_5094253_4 transcription regulator activity - - - 0.0001967 53.0
CMS2_k127_5094343_0 Ubiquitin-2 like Rad60 SUMO-like K12160 GO:0001221,GO:0001222,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006464,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016604,GO:0016605,GO:0016925,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019899,GO:0030162,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031386,GO:0031625,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032434,GO:0032436,GO:0032446,GO:0036211,GO:0042176,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0061136,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0080090,GO:1901564,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:2000058,GO:2000060 - 0.00009486 53.0
CMS2_k127_5101263_0 PFAM type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 531.0
CMS2_k127_5101263_1 Type II secretion system (T2SS), protein F K07333 - - 0.000000000764 66.0
CMS2_k127_5112577_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003868 266.0
CMS2_k127_5112577_1 PFAM Nitroreductase - - - 0.000007459 53.0
CMS2_k127_5121124_0 Histone H2B K11252,K11275 GO:0000228,GO:0000785,GO:0000786,GO:0000788,GO:0000790,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0031497,GO:0031974,GO:0031981,GO:0032991,GO:0032993,GO:0034622,GO:0034728,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044815,GO:0051276,GO:0065003,GO:0065004,GO:0070013,GO:0071103,GO:0071824,GO:0071840,GO:0097159,GO:1901363 - 0.0000000000000001218 87.0
CMS2_k127_5121124_1 - - - - 0.000000000001905 80.0
CMS2_k127_5127242_0 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 334.0
CMS2_k127_5127242_1 PFAM regulatory protein AsnC Lrp family K03719 - - 0.0003196 46.0
CMS2_k127_5140931_0 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000001392 123.0
CMS2_k127_5140931_1 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000001475 107.0
CMS2_k127_5145564_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 332.0
CMS2_k127_5153447_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 593.0
CMS2_k127_5153447_1 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000989 252.0
CMS2_k127_5153447_2 Methyl-transferase - - - 0.000000000000000000000000000000000000000000006098 171.0
CMS2_k127_5153447_3 thiolester hydrolase activity K01259,K06889,K21193 - 3.4.11.5 0.0000000000000000000000001073 119.0
CMS2_k127_5153447_4 Belongs to the peptidase S8 family - - - 0.00000000000000000000001471 115.0
CMS2_k127_5157998_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 321.0
CMS2_k127_5157998_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000008409 59.0
CMS2_k127_5162427_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 4.71e-238 756.0
CMS2_k127_5162427_1 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 365.0
CMS2_k127_5164795_0 SAF K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 360.0
CMS2_k127_5164795_1 Cytidylyltransferase - - - 0.00000000000000001593 83.0
CMS2_k127_5164795_2 UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing K01791,K18429 - 3.2.1.184,5.1.3.14 0.000000000003871 68.0
CMS2_k127_5166098_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 297.0
CMS2_k127_5179663_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 614.0
CMS2_k127_5179663_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 336.0
CMS2_k127_5179708_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1177.0
CMS2_k127_5179708_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 - 2.7.7.6 0.0 1170.0
CMS2_k127_5179708_2 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 438.0
CMS2_k127_5179708_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 410.0
CMS2_k127_5179708_4 Participates in transcription termination K02600 - - 0.0000000000000000000000000003263 119.0
CMS2_k127_5179708_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000004112 102.0
CMS2_k127_5179708_6 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.00000000000000000002779 93.0
CMS2_k127_5189850_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003024 255.0
CMS2_k127_5189850_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000008192 222.0
CMS2_k127_5189850_2 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000002962 166.0
CMS2_k127_5189850_3 - K03561,K12287 - - 0.00000000000000000000000000000000000002927 151.0
CMS2_k127_5189850_4 PFAM PKD domain containing protein - - - 0.00000000000000152 86.0
CMS2_k127_5189850_5 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000002415 63.0
CMS2_k127_5199659_0 - K03561,K12287 - - 0.0000000000000000000000000000000000009796 154.0
CMS2_k127_5202895_0 Phage terminase, large subunit, PBSX family K06909 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 501.0
CMS2_k127_5202895_1 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 411.0
CMS2_k127_5202895_10 ECF sigma factor K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.00003714 49.0
CMS2_k127_5202895_11 - - - - 0.00007765 49.0
CMS2_k127_5202895_12 - - - - 0.0003245 49.0
CMS2_k127_5202895_13 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0005457 52.0
CMS2_k127_5202895_14 NUMOD4 motif - - - 0.0009014 46.0
CMS2_k127_5202895_2 - - - - 0.00000000000000000000000000000000000000001299 160.0
CMS2_k127_5202895_3 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000003436 72.0
CMS2_k127_5202895_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000006868 65.0
CMS2_k127_5202895_5 Von Willebrand factor - - - 0.0000000918 65.0
CMS2_k127_5202895_6 Thymidylate synthase K00560 - 2.1.1.45 0.000001807 58.0
CMS2_k127_5202895_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000007203 57.0
CMS2_k127_5202895_8 Chromatin organization modifier domain - - - 0.00002169 55.0
CMS2_k127_5202895_9 dUTPase - - - 0.00003313 52.0
CMS2_k127_5214272_0 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000006683 187.0
CMS2_k127_5214272_1 FAD dependent oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000001999 61.0
CMS2_k127_5215519_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 465.0
CMS2_k127_5215519_1 Thiamine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 317.0
CMS2_k127_5215519_2 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000005251 216.0
CMS2_k127_5215519_3 PFAM Nitroreductase - - - 0.0000000000000000001222 102.0
CMS2_k127_5223646_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000009157 167.0
CMS2_k127_5223646_1 PFAM Luciferase-like monooxygenase - - - 0.00000000000001563 77.0
CMS2_k127_5223646_2 Metallo-beta-lactamase superfamily - - - 0.0000000715 55.0
CMS2_k127_5229711_0 ASNC family K03718 - - 0.000000001169 69.0
CMS2_k127_5229711_1 COG1522 Transcriptional regulators K03719 - - 0.00000002054 65.0
CMS2_k127_5229711_2 Transmembrane secretion effector - - - 0.0000001374 63.0
CMS2_k127_5229711_3 transcriptional regulator K03718 - - 0.0000006544 61.0
CMS2_k127_5229711_4 helix_turn_helix ASNC type K03719 - - 0.000001141 60.0
CMS2_k127_524532_0 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 338.0
CMS2_k127_524532_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 330.0
CMS2_k127_524532_2 PFAM LemA - - - 0.0000000000000000000000000000000000000000000000000000000000001916 216.0
CMS2_k127_524532_3 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000003845 213.0
CMS2_k127_5288458_0 Peptidase family C25, C terminal ig-like domain K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.00000007536 64.0
CMS2_k127_5288458_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000001204 63.0
CMS2_k127_5300970_0 Pfam:DUF1628 - - - 0.00000000000000009009 96.0
CMS2_k127_5300970_1 self proteolysis - - - 0.00005973 57.0
CMS2_k127_5307946_0 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001127 261.0
CMS2_k127_5307946_1 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000000000000000004056 224.0
CMS2_k127_5309359_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 524.0
CMS2_k127_5309359_1 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000002636 216.0
CMS2_k127_5309359_2 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000000000000000001906 165.0
CMS2_k127_5309359_3 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000017 111.0
CMS2_k127_5309359_4 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000008283 72.0
CMS2_k127_5309359_5 structural constituent of ribosome K02974 - - 0.00000105 51.0
CMS2_k127_531395_0 Flavin containing amine oxidoreductase K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 577.0
CMS2_k127_531395_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 359.0
CMS2_k127_531395_2 UV-endonuclease UvdE K13281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 355.0
CMS2_k127_531395_3 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 338.0
CMS2_k127_531395_4 lycopene cyclase - - - 0.000000000000000000000000000000000000000000000000000002768 199.0
CMS2_k127_531395_5 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000004823 107.0
CMS2_k127_531395_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000006517 108.0
CMS2_k127_531395_7 - - - - 0.0000001036 60.0
CMS2_k127_5317413_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 503.0
CMS2_k127_5317413_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 333.0
CMS2_k127_5320720_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 440.0
CMS2_k127_5320720_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003398 251.0
CMS2_k127_5320720_10 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000002447 64.0
CMS2_k127_5320720_2 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000009879 229.0
CMS2_k127_5320720_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000001472 183.0
CMS2_k127_5320720_4 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000005885 168.0
CMS2_k127_5320720_5 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000004298 177.0
CMS2_k127_5320720_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000846 162.0
CMS2_k127_5320720_7 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000000003875 109.0
CMS2_k127_5320720_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.00000000000001006 76.0
CMS2_k127_5320720_9 - - - - 0.0000000000001938 73.0
CMS2_k127_5321807_0 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000002532 202.0
CMS2_k127_5326679_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 602.0
CMS2_k127_5326679_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 477.0
CMS2_k127_5326679_2 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 319.0
CMS2_k127_5326679_3 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 308.0
CMS2_k127_5326679_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 308.0
CMS2_k127_5326679_5 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000008461 271.0
CMS2_k127_5326679_6 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000001824 170.0
CMS2_k127_5326679_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000002425 166.0
CMS2_k127_5355045_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000004237 223.0
CMS2_k127_5355045_1 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000006444 66.0
CMS2_k127_5355045_2 Glycosyl hydrolase family 12 K01179,K01218,K20276 - 3.2.1.4,3.2.1.78 0.0000001273 55.0
CMS2_k127_5355409_0 type II secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 575.0
CMS2_k127_5355409_1 type II secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 544.0
CMS2_k127_5355409_2 PFAM Type II secretion system F domain K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 316.0
CMS2_k127_5355409_3 SMART AAA ATPase K07331 - - 0.0000000000000000000000000000000000000001549 158.0
CMS2_k127_5355409_4 Archaebacterial flagellin K07330 - - 0.0000000000000000173 87.0
CMS2_k127_5355409_5 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000002269 66.0
CMS2_k127_5357432_0 TIGRFAM Small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 392.0
CMS2_k127_5357432_1 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 334.0
CMS2_k127_5357432_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000002926 247.0
CMS2_k127_5357432_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000001677 110.0
CMS2_k127_5357432_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0003133 43.0
CMS2_k127_536305_0 Pentaxin family K12287 - - 0.0000000002194 70.0
CMS2_k127_5369156_0 COG0058 Glucan phosphorylase - - - 1.739e-221 700.0
CMS2_k127_5369156_1 TIGRFAM glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 460.0
CMS2_k127_5369156_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001026 284.0
CMS2_k127_5369156_3 Starch synthase catalytic domain - - - 0.0000000000000000000000000002332 116.0
CMS2_k127_5371743_0 Propeptide_C25 - - - 0.00009079 56.0
CMS2_k127_5373996_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001068 237.0
CMS2_k127_5373996_1 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000000000000000000000000000000000000000000000002801 197.0
CMS2_k127_5373996_2 NUDIX domain - - - 0.0000000000000000000001323 100.0
CMS2_k127_5374482_0 alginic acid biosynthetic process - - - 0.00000000167 69.0
CMS2_k127_5396575_0 Aromatic amino acid lyase K01745 - 4.3.1.3 3.199e-270 838.0
CMS2_k127_5396575_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 406.0
CMS2_k127_5396575_2 Peptidase family M28 - - - 0.0000000000000000002924 98.0
CMS2_k127_5401345_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 9.249e-240 747.0
CMS2_k127_5401345_1 PFAM AMP-dependent synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 575.0
CMS2_k127_5401345_2 ATP-grasp domain K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000006863 190.0
CMS2_k127_5401345_3 - - - - 0.00000000000000000000000003006 119.0
CMS2_k127_5401759_0 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 413.0
CMS2_k127_5401759_1 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00002852 48.0
CMS2_k127_5409773_0 Lysine exporter protein LysE YggA - - - 0.00000000000000000000000000000000000002818 151.0
CMS2_k127_5409773_1 - - - - 0.0001191 50.0
CMS2_k127_5410495_0 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.00000000000004383 79.0
CMS2_k127_5410495_1 PFAM conserved K07027 - - 0.000043 53.0
CMS2_k127_5412364_0 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000000000001368 208.0
CMS2_k127_5412364_1 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000002116 107.0
CMS2_k127_5412364_2 Domain present in carbohydrate binding proteins and sugar hydrolses - - - 0.0000000000000000004039 98.0
CMS2_k127_5415565_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 398.0
CMS2_k127_5415565_1 PFAM zinc iron permease K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001416 246.0
CMS2_k127_5415565_2 AraC-like ligand binding domain - - - 0.00000000000000000000000000006391 119.0
CMS2_k127_5415565_4 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000001803 81.0
CMS2_k127_5418989_0 Right handed beta helix region - - - 0.00000000000000000000000000000000000001009 164.0
CMS2_k127_5420948_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000399 256.0
CMS2_k127_5420948_1 Universal stress protein family - - - 0.000000000001691 73.0
CMS2_k127_5422622_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 456.0
CMS2_k127_5422622_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 421.0
CMS2_k127_5422622_2 C-terminal domain of CHU protein family - - - 0.0000000000000000000000000003685 133.0
CMS2_k127_5422622_3 - - - - 0.000002071 61.0
CMS2_k127_5446457_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 492.0
CMS2_k127_5446457_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 289.0
CMS2_k127_5446457_2 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001663 258.0
CMS2_k127_5446457_3 Translin family K07477 - - 0.00000000000000000000000000000000000279 147.0
CMS2_k127_5446457_4 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000004884 143.0
CMS2_k127_5446457_5 prohibitin homologues - - - 0.00000000000000000000000000007631 118.0
CMS2_k127_5446457_6 Archaeal TRASH domain - - - 0.00000898 54.0
CMS2_k127_5459571_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000005238 220.0
CMS2_k127_5459571_1 GxGYxYP putative glycoside hydrolase C-terminal domain K03088 - - 0.00002288 53.0
CMS2_k127_5466283_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 469.0
CMS2_k127_5466283_1 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000001102 75.0
CMS2_k127_5466283_2 - - - - 0.0000006085 55.0
CMS2_k127_5466917_0 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000004998 156.0
CMS2_k127_5466917_1 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000004131 144.0
CMS2_k127_5466917_2 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000011 67.0
CMS2_k127_5466917_3 Winged helix-turn-helix domain (DUF2582) - - - 0.0000001379 58.0
CMS2_k127_5466917_4 Winged helix-turn-helix domain (DUF2582) - - - 0.0000004804 57.0
CMS2_k127_5466917_5 Winged helix-turn-helix domain (DUF2582) - - - 0.000004234 51.0
CMS2_k127_5510087_0 DNA polymerase K02327 - 2.7.7.7 0.00000000000000001523 95.0
CMS2_k127_5540761_0 DEAD DEAH box helicase domain protein K10896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 614.0
CMS2_k127_5540761_1 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.0000000002382 73.0
CMS2_k127_5560541_0 Leucine Rich repeat - - - 0.0000000000002106 82.0
CMS2_k127_5560541_1 2-acylglycerol O-acyltransferase activity K14457,K14950 - 2.3.1.22 0.0000000552 63.0
CMS2_k127_5564455_0 transferase activity, transferring glycosyl groups K01179,K01356,K13735,K21449 - 3.2.1.4,3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 322.0
CMS2_k127_5564455_1 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000001137 252.0
CMS2_k127_5569813_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 292.0
CMS2_k127_5569813_1 PFAM Peptidase C1A, papain - - - 0.0000000000000000000000000000008004 141.0
CMS2_k127_5569813_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000002065 71.0
CMS2_k127_5570365_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.033e-213 671.0
CMS2_k127_5570365_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000005967 135.0
CMS2_k127_5602815_0 Protein phosphatase 2C 55 K17508 - 3.1.3.16 0.0000639 48.0
CMS2_k127_5608463_0 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000135 265.0
CMS2_k127_5608463_1 - - - - 0.000000000001727 72.0
CMS2_k127_5608463_2 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000002515 72.0
CMS2_k127_5616616_0 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000431 259.0
CMS2_k127_5616616_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000001094 154.0
CMS2_k127_5638923_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 474.0
CMS2_k127_5638923_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 301.0
CMS2_k127_5638923_2 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003805 271.0
CMS2_k127_5638923_3 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000004217 263.0
CMS2_k127_5638923_4 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000003632 211.0
CMS2_k127_5638923_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000001281 184.0
CMS2_k127_5638923_6 PFAM regulatory protein, ArsR - - - 0.00000000000000009862 89.0
CMS2_k127_5638923_7 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000002762 79.0
CMS2_k127_5638923_8 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000002794 70.0
CMS2_k127_5658511_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 310.0
CMS2_k127_5671817_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 1.153e-194 616.0
CMS2_k127_5671817_1 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000028 228.0
CMS2_k127_5671817_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000009833 93.0
CMS2_k127_5672109_0 PFAM type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 500.0
CMS2_k127_5683721_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 472.0
CMS2_k127_5683721_1 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000408 215.0
CMS2_k127_5683721_2 PFAM OsmC family protein K09136 - - 0.0000000000000000000000000000000000006883 144.0
CMS2_k127_5683721_3 binds to the 23S rRNA K02921 - - 0.0000000000000000000000001056 109.0
CMS2_k127_5683721_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000009192 57.0
CMS2_k127_5683721_5 Transcription factor Pcc1 K09741 - - 0.000000578 54.0
CMS2_k127_5684969_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 384.0
CMS2_k127_5684969_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000127 182.0
CMS2_k127_5684969_2 PFAM Fatty acid hydroxylase K15746 - 1.14.15.24 0.0000000000000000000000000000000004722 136.0
CMS2_k127_5690394_0 metallocarboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000000004285 207.0
CMS2_k127_5693704_0 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.00000001223 68.0
CMS2_k127_5693704_1 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.0000003811 62.0
CMS2_k127_5700253_0 Pyruvate:ferredoxin oxidoreductase core domain II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 366.0
CMS2_k127_5700253_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 319.0
CMS2_k127_5700253_2 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.00000000000000000000001855 108.0
CMS2_k127_5723654_0 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000003783 82.0
CMS2_k127_5723654_1 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.0000004498 53.0
CMS2_k127_5761667_0 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 375.0
CMS2_k127_5761667_1 glutamine synthetase K01915 GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 336.0
CMS2_k127_5777879_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 376.0
CMS2_k127_5777879_1 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000009498 120.0
CMS2_k127_5777879_2 Cysteine-rich domain - - - 0.0000000000000000000000003352 106.0
CMS2_k127_5780564_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 433.0
CMS2_k127_5780564_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 290.0
CMS2_k127_5780564_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000002833 101.0
CMS2_k127_5800788_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 567.0
CMS2_k127_5806636_0 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000001327 179.0
CMS2_k127_5806636_1 response regulator, receiver K07668,K07669 - - 0.00000000000000000000001987 105.0
CMS2_k127_5808739_0 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007638 225.0
CMS2_k127_5808739_1 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.000000000000000000000000000000000000000000000000000113 193.0
CMS2_k127_5832385_0 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000009552 138.0
CMS2_k127_5832385_1 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000007425 138.0
CMS2_k127_5832385_2 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000001209 113.0
CMS2_k127_5839625_0 - - - - 0.0000000000000000127 96.0
CMS2_k127_5847389_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000009569 187.0
CMS2_k127_5855047_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 361.0
CMS2_k127_5855047_1 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 311.0
CMS2_k127_5855047_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001949 287.0
CMS2_k127_5855047_3 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000003169 124.0
CMS2_k127_5855047_4 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000002326 88.0
CMS2_k127_5867060_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 287.0
CMS2_k127_5867060_1 Domain of unknown function (DUF1805) - - - 0.000000000000000000004975 95.0
CMS2_k127_5874856_0 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.000000000000000000000000000000000000000000000000000000000000000001789 244.0
CMS2_k127_5880396_0 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000002103 138.0
CMS2_k127_5880396_1 Helix-turn-helix domain - - - 0.00001383 49.0
CMS2_k127_589255_0 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0000002108 64.0
CMS2_k127_5907606_0 phenylalanine-tRNA ligase activity K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 351.0
CMS2_k127_5907606_1 Family of unknown function (DUF438) K09155 - - 0.000000000000000000000000000186 119.0
CMS2_k127_5907805_0 PFAM PP-loop domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 308.0
CMS2_k127_5907805_1 metal ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000002332 233.0
CMS2_k127_5907805_2 Rad51 - - - 0.0000000001027 63.0
CMS2_k127_5909935_0 - - - - 0.00000000000009573 83.0
CMS2_k127_5932355_0 - - - - 0.0000002617 59.0
CMS2_k127_5933261_0 COG0168 Trk-type K transport systems, membrane components K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 386.0
CMS2_k127_5933261_1 PFAM TrkA-N domain K03499 - - 0.00000000000000000000000000000000000004916 151.0
CMS2_k127_5933261_2 - - - - 0.000000000000004477 78.0
CMS2_k127_5933261_3 Sterol carrier protein - - - 0.000000000008718 71.0
CMS2_k127_5945046_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 385.0
CMS2_k127_5945046_1 PFAM Circadian clock protein KaiC - - - 0.0000000000000000000000005693 114.0
CMS2_k127_5945046_2 DNA polymerase alpha chain like domain - - - 0.0000000000000000000409 95.0
CMS2_k127_5945046_3 L-ribulose-5-phosphate 4-epimerase K01628 - 4.1.2.17 0.00002005 54.0
CMS2_k127_5969224_0 PFAM Citrate lyase, alpha subunit K01643 - 2.8.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 388.0
CMS2_k127_5969224_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 347.0
CMS2_k127_5969224_2 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000001522 258.0
CMS2_k127_5969224_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.00000000000000000000000000000000000000000001903 174.0
CMS2_k127_5969224_4 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000002821 164.0
CMS2_k127_5969224_5 Nicotianamine synthase protein - - - 0.00000000000003223 81.0
CMS2_k127_5975560_0 PKD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 344.0
CMS2_k127_5975560_1 NHL repeat - - - 0.00000000000000000000001251 115.0
CMS2_k127_5975560_2 domain, Protein - - - 0.00007118 54.0
CMS2_k127_5979627_0 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 0.00002694 57.0
CMS2_k127_5982352_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.685e-269 848.0
CMS2_k127_5982352_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 619.0
CMS2_k127_5982352_2 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000003347 188.0
CMS2_k127_5982352_3 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000000000000000001938 167.0
CMS2_k127_5982352_4 TIGRFAM indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000002173 169.0
CMS2_k127_5982352_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000005508 89.0
CMS2_k127_6005234_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000001671 168.0
CMS2_k127_6005234_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000004866 115.0
CMS2_k127_6005234_2 Evidence 5 No homology to any previously reported sequences K01361,K13277 - 3.4.21.96 0.000000000000000000000000006118 123.0
CMS2_k127_6005234_3 Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.000000062 66.0
CMS2_k127_6020112_0 Fic/DOC family - - - 0.0001414 51.0
CMS2_k127_6022729_0 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 464.0
CMS2_k127_6022729_1 dihydromethanopterin reductase activity K00176,K06411,K12527 - 1.2.7.3,1.97.1.9 0.0000000000000002448 80.0
CMS2_k127_6022729_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00001929 46.0
CMS2_k127_6025953_0 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 444.0
CMS2_k127_6031841_0 peptidyl-lysine modification to peptidyl-hypusine K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 455.0
CMS2_k127_6031841_1 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 436.0
CMS2_k127_6031841_10 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000001015 103.0
CMS2_k127_6031841_11 cluster protein-associated redox disulfide domain - - - 0.00000000000001401 76.0
CMS2_k127_6031841_12 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000002284 77.0
CMS2_k127_6031841_2 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 316.0
CMS2_k127_6031841_3 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 294.0
CMS2_k127_6031841_4 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000005936 259.0
CMS2_k127_6031841_5 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000003273 256.0
CMS2_k127_6031841_6 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000001277 195.0
CMS2_k127_6031841_7 peptide-methionine (R)-S-oxide reductase activity K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000006823 175.0
CMS2_k127_6031841_8 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.00000000000000000000000000000006508 130.0
CMS2_k127_6031841_9 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000001372 116.0
CMS2_k127_6049330_0 Proton-conducting membrane transporter K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 378.0
CMS2_k127_6049330_1 PFAM respiratory-chain NADH dehydrogenase, subunit 1 - - - 0.00000000000000000000000000000000000000000000000000000000000001609 220.0
CMS2_k127_6049330_2 - - - - 0.000000000000000000000001542 107.0
CMS2_k127_6055063_0 PD-(D/E)XK nuclease superfamily K07465 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 315.0
CMS2_k127_6055063_1 Papain family cysteine protease - - - 0.00000000000000000000000000000000003782 153.0
CMS2_k127_6055063_2 Serine aminopeptidase, S33 - - - 0.00000000000000359 81.0
CMS2_k127_6055063_3 Serine aminopeptidase, S33 - - - 0.00000001162 60.0
CMS2_k127_6055063_4 Peptidase family C25 - - - 0.0000002108 64.0
CMS2_k127_6055063_5 carboxylic ester hydrolase activity - - - 0.000004427 54.0
CMS2_k127_6061151_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.904e-210 673.0
CMS2_k127_6061151_1 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 559.0
CMS2_k127_6061151_2 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000001944 186.0
CMS2_k127_6061151_3 - - - - 0.00000000000000000000003152 100.0
CMS2_k127_6079511_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000002784 146.0
CMS2_k127_6093365_0 Transposase and inactivated derivatives - - - 0.000000000000000000000000000223 128.0
CMS2_k127_6093365_1 DNA restriction-modification system - - - 0.0000000000000000000000009078 107.0
CMS2_k127_6117381_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 5.693e-197 623.0
CMS2_k127_6117381_1 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 564.0
CMS2_k127_6117381_2 RmlD substrate binding domain K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 495.0
CMS2_k127_6117381_3 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000001374 175.0
CMS2_k127_6117381_4 regulator of amino acid metabolism K07103 - - 0.0000000000000000000000000000000000001085 148.0
CMS2_k127_6125966_0 - - - - 0.0001534 49.0
CMS2_k127_61654_0 2-acylglycerol O-acyltransferase activity K14457,K14950 - 2.3.1.22 0.00000000000000000000000003202 111.0
CMS2_k127_618678_0 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 485.0
CMS2_k127_618678_1 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 463.0
CMS2_k127_618678_2 Aminotransferase class-III K00821,K03918,K07250,K13524,K20428 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000002697 224.0
CMS2_k127_6193967_0 L-asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 488.0
CMS2_k127_6193967_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 461.0
CMS2_k127_6193967_2 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000001078 102.0
CMS2_k127_6197538_0 AIR synthase related protein domain protein K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 449.0
CMS2_k127_6197538_1 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 391.0
CMS2_k127_6197538_2 Thiamine-phosphate synthase K21220 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000814 218.0
CMS2_k127_6197538_3 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.000000000000000000000000000000000000000000001277 168.0
CMS2_k127_6197538_4 Transcriptional regulator K07108 - - 0.000000000000005511 79.0
CMS2_k127_6197538_5 PKD domain containing protein K01183 - 3.2.1.14 0.0000000000001691 78.0
CMS2_k127_6208929_0 thiolester hydrolase activity K06889 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000035 262.0
CMS2_k127_6212212_0 flavodoxin nitric oxide synthase - - - 6.839e-198 623.0
CMS2_k127_621402_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 483.0
CMS2_k127_621402_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 360.0
CMS2_k127_621402_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000003549 144.0
CMS2_k127_6277429_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006538 269.0
CMS2_k127_6277429_1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.00000000000002093 77.0
CMS2_k127_6277429_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00002222 56.0
CMS2_k127_6285656_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.539e-212 670.0
CMS2_k127_6290044_0 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000006299 258.0
CMS2_k127_6290044_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000004077 192.0
CMS2_k127_6290044_2 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000004944 158.0
CMS2_k127_6290044_3 Helix-turn-helix XRE-family like proteins K03627 - - 0.0000000000000001246 85.0
CMS2_k127_6290044_5 ABC-type uncharacterized transport system - - - 0.00000005711 65.0
CMS2_k127_6291324_0 - - - - 0.000000000000000000000000000009607 134.0
CMS2_k127_6291324_1 cellulose binding - - - 0.0000000000000000000003502 106.0
CMS2_k127_6291877_0 TIGRFAM Phage - - - 0.000000000000000000000000000000000000000000000000000000000004352 226.0
CMS2_k127_6291877_1 Phage portal protein - - - 0.000000000000000000000000000000000000003071 164.0
CMS2_k127_6291877_2 Bacterial PH domain - - - 0.0000000000000000000000000000000000001516 146.0
CMS2_k127_6297250_0 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 305.0
CMS2_k127_6297250_1 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000000000000000000001362 183.0
CMS2_k127_6297250_2 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000001102 151.0
CMS2_k127_6297250_3 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000006908 72.0
CMS2_k127_6297250_4 Transcriptional regulator K07108 - - 0.0000000000000965 79.0
CMS2_k127_6310595_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000004695 208.0
CMS2_k127_6310595_1 Belongs to the UPF0178 family - - - 0.0000000000000000000000000000000000000000000001063 171.0
CMS2_k127_6310595_2 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000582 159.0
CMS2_k127_6310595_3 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000009078 107.0
CMS2_k127_6313905_0 PHP C-terminal domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 436.0
CMS2_k127_6313905_1 MatE - - - 0.00000000000000000000000000000000000000000000000000000000003845 210.0
CMS2_k127_6313905_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000003298 173.0
CMS2_k127_6357797_0 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 593.0
CMS2_k127_6357797_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 573.0
CMS2_k127_6357797_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 396.0
CMS2_k127_6357797_3 Belongs to the peptidase S16 family K06870 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 308.0
CMS2_k127_6357797_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000406 226.0
CMS2_k127_6357797_5 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.000000000000000000000000000000000000000000000000000000001454 214.0
CMS2_k127_6357797_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000005501 143.0
CMS2_k127_6372973_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000004513 186.0
CMS2_k127_6372973_1 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000003965 139.0
CMS2_k127_6377589_0 TIGRFAM UbiD family decarboxylase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006703 285.0
CMS2_k127_6377589_1 tRNA pseudouridine synthase D K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005266 278.0
CMS2_k127_6377589_2 GHMP kinases C terminal K00869 - 2.7.1.36 0.000000000000000000000000000000000000000006324 160.0
CMS2_k127_6377589_3 - - - - 0.000000000000008662 78.0
CMS2_k127_6386524_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002357 282.0
CMS2_k127_6386524_1 Methionine biosynthesis protein MetW - - - 0.00000000000000000001149 102.0
CMS2_k127_6399612_0 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 459.0
CMS2_k127_6399612_1 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 320.0
CMS2_k127_6399612_2 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 314.0
CMS2_k127_6399612_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 305.0
CMS2_k127_6399612_4 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 305.0
CMS2_k127_6399612_5 membrane - - - 0.0000000000000000000000000000000000000000000000000005859 198.0
CMS2_k127_6403791_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 328.0
CMS2_k127_6403791_1 Archaeal holliday junction resolvase (hjc) - - - 0.0000000000000000000000000000000000000000000001259 173.0
CMS2_k127_6403791_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000001353 142.0
CMS2_k127_6403791_3 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000006572 143.0
CMS2_k127_6403791_4 AMP binding - - - 0.000000000000001783 81.0
CMS2_k127_6403791_5 - - - - 0.0000000000007743 72.0
CMS2_k127_6403791_6 GHMP kinases N terminal domain K06982 - 2.7.1.169 0.00055 46.0
CMS2_k127_6406284_0 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004597 273.0
CMS2_k127_6406284_1 membrane - - - 0.0000000107 62.0
CMS2_k127_6406284_2 - - - - 0.0003405 46.0
CMS2_k127_6406784_0 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 310.0
CMS2_k127_6410240_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000002025 251.0
CMS2_k127_6410240_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000001043 74.0
CMS2_k127_6411958_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.00000000000000000000000000000000000000000000000005463 181.0
CMS2_k127_6411958_1 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000004096 89.0
CMS2_k127_6413614_0 deoxyribonuclease I activity K06131,K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000108 262.0
CMS2_k127_6413614_1 extracellular nuclease K07004 - - 0.00001533 58.0
CMS2_k127_6415517_0 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 - 3.8.1.5 0.0000953 54.0
CMS2_k127_6415517_1 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0009457 52.0
CMS2_k127_6431126_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1217.0
CMS2_k127_6431126_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 405.0
CMS2_k127_6431126_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00125 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001363 264.0
CMS2_k127_6431126_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000003964 218.0
CMS2_k127_6431126_4 PFAM NADH ubiquinone oxidoreductase, 20 K14128 - 1.8.98.5 0.000000000000000000000000000000001089 132.0
CMS2_k127_644134_0 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000007224 143.0
CMS2_k127_6454374_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 296.0
CMS2_k127_6454374_1 - - - - 0.000000001371 63.0
CMS2_k127_6496702_0 SNF2 family N-terminal domain - GO:0000003,GO:0000109,GO:0000113,GO:0000228,GO:0000775,GO:0000776,GO:0000777,GO:0000778,GO:0000779,GO:0000780,GO:0000793,GO:0000794,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005730,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006281,GO:0006282,GO:0006289,GO:0006325,GO:0006333,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007530,GO:0007531,GO:0007533,GO:0008094,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010605,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0022413,GO:0022414,GO:0030154,GO:0031323,GO:0031324,GO:0031974,GO:0031981,GO:0032182,GO:0032183,GO:0032502,GO:0032505,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0045165,GO:0045738,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0098687,GO:1901360,GO:1901363,GO:1990391,GO:2000779,GO:2000780,GO:2001020,GO:2001021,GO:2001032,GO:2001033 - 0.000000000000001702 92.0
CMS2_k127_6496702_1 SNF2 family N-terminal domain K15083 - - 0.000000000000006753 90.0
CMS2_k127_6515609_0 SNF2 domain-containing protein helicase domain-containing protein RING finger domain-containing protein K15083 GO:0000109,GO:0000166,GO:0000720,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004842,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006290,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016043,GO:0016462,GO:0016567,GO:0016740,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019787,GO:0030554,GO:0032392,GO:0032446,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051276,GO:0051716,GO:0061630,GO:0061659,GO:0070035,GO:0070647,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140096,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1990391 - 0.000000000004648 76.0
CMS2_k127_6515609_1 thrombopoietin-mediated signaling pathway K13190 GO:0000003,GO:0000122,GO:0000375,GO:0000377,GO:0000381,GO:0000398,GO:0001510,GO:0001525,GO:0001568,GO:0001569,GO:0001654,GO:0001763,GO:0001890,GO:0001944,GO:0002009,GO:0002376,GO:0002520,GO:0002682,GO:0002683,GO:0003002,GO:0003006,GO:0003007,GO:0003205,GO:0003206,GO:0003231,GO:0003279,GO:0003281,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0007221,GO:0007275,GO:0007389,GO:0007423,GO:0007444,GO:0007447,GO:0007507,GO:0007549,GO:0008150,GO:0008152,GO:0008380,GO:0009048,GO:0009451,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0016070,GO:0016071,GO:0016556,GO:0016604,GO:0016607,GO:0019219,GO:0019221,GO:0019222,GO:0022414,GO:0023051,GO:0023052,GO:0023056,GO:0030111,GO:0030177,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032259,GO:0032501,GO:0032502,GO:0032991,GO:0034097,GO:0034641,GO:0034708,GO:0035220,GO:0035222,GO:0035239,GO:0035295,GO:0036396,GO:0038163,GO:0040029,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043484,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0045293,GO:0045595,GO:0045596,GO:0045637,GO:0045638,GO:0045652,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0048024,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048536,GO:0048583,GO:0048584,GO:0048608,GO:0048646,GO:0048729,GO:0048731,GO:0048749,GO:0048754,GO:0048856,GO:0050684,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051093,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051241,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0060411,GO:0060412,GO:0060429,GO:0060562,GO:0060674,GO:0060828,GO:0061138,GO:0061458,GO:0065007,GO:0070013,GO:0070098,GO:0070887,GO:0071310,GO:0071345,GO:0071704,GO:0072358,GO:0072359,GO:0080009,GO:0080090,GO:0090263,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1902494,GO:1902679,GO:1902680,GO:1903311,GO:1903506,GO:1903507,GO:1903508,GO:1903706,GO:1903707,GO:1990234,GO:2000026,GO:2000112,GO:2000113,GO:2000736,GO:2000737,GO:2001141 - 0.0002429 52.0
CMS2_k127_6519525_0 helicase superfamily c-terminal domain K03724 - - 7.249e-251 802.0
CMS2_k127_6519525_1 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 567.0
CMS2_k127_6531866_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008701 291.0
CMS2_k127_6531866_1 PFAM Peptidase M18, aminopeptidase I K01267 - 3.4.11.21 0.000000000000000000000006397 101.0
CMS2_k127_6544661_0 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 327.0
CMS2_k127_6544661_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 321.0
CMS2_k127_6544661_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000001187 218.0
CMS2_k127_6544661_3 FMN binding - - - 0.0000000000000000000000000000002084 132.0
CMS2_k127_6544661_4 PFAM Transcriptional regulator TrmB - - - 0.00000000000000000004977 94.0
CMS2_k127_6544661_5 MMPL family K07003 - - 0.000000000000000004264 94.0
CMS2_k127_6544661_6 Protein of unknown function (DUF357) K09728 - - 0.000000000002951 72.0
CMS2_k127_6549469_0 alpha-2 macroglobulin receptor activity K04550,K06233,K20049 GO:0001523,GO:0001568,GO:0001701,GO:0001775,GO:0001944,GO:0002020,GO:0002252,GO:0002263,GO:0002265,GO:0002376,GO:0003205,GO:0003279,GO:0003674,GO:0005041,GO:0005044,GO:0005102,GO:0005215,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005768,GO:0005769,GO:0005886,GO:0005887,GO:0005905,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0006810,GO:0006897,GO:0006898,GO:0006909,GO:0006955,GO:0007154,GO:0007165,GO:0007186,GO:0007205,GO:0007275,GO:0007399,GO:0007417,GO:0007507,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008283,GO:0008565,GO:0009653,GO:0009719,GO:0009790,GO:0009792,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009968,GO:0009987,GO:0010001,GO:0010033,GO:0010243,GO:0010517,GO:0010604,GO:0010640,GO:0010642,GO:0010646,GO:0010648,GO:0010715,GO:0010721,GO:0010874,GO:0010875,GO:0010941,GO:0010942,GO:0010975,GO:0010977,GO:0012505,GO:0012506,GO:0014002,GO:0014910,GO:0014912,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016101,GO:0016125,GO:0016192,GO:0016323,GO:0016964,GO:0019222,GO:0019899,GO:0021782,GO:0022008,GO:0023051,GO:0023052,GO:0023057,GO:0030100,GO:0030111,GO:0030135,GO:0030136,GO:0030139,GO:0030154,GO:0030178,GO:0030226,GO:0030228,GO:0030276,GO:0030334,GO:0030336,GO:0030425,GO:0030659,GO:0030666,GO:0031090,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031344,GO:0031345,GO:0031410,GO:0031623,GO:0031982,GO:0032050,GO:0032092,GO:0032268,GO:0032270,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032429,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032956,GO:0032970,GO:0032991,GO:0033036,GO:0033043,GO:0034185,GO:0035239,GO:0035295,GO:0035904,GO:0035909,GO:0036477,GO:0038023,GO:0038024,GO:0040012,GO:0040013,GO:0042063,GO:0042176,GO:0042221,GO:0042886,GO:0042953,GO:0042954,GO:0042981,GO:0042995,GO:0043005,GO:0043009,GO:0043025,GO:0043066,GO:0043067,GO:0043069,GO:0043112,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043235,GO:0043277,GO:0043393,GO:0043394,GO:0043395,GO:0043523,GO:0043524,GO:0044093,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044872,GO:0044877,GO:0045056,GO:0045184,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045732,GO:0045807,GO:0046872,GO:0048143,GO:0048468,GO:0048471,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048699,GO:0048708,GO:0048731,GO:0048844,GO:0048856,GO:0048869,GO:0050750,GO:0050767,GO:0050768,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051093,GO:0051098,GO:0051099,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051270,GO:0051271,GO:0051336,GO:0051493,GO:0051716,GO:0051960,GO:0051961,GO:0060089,GO:0060191,GO:0060255,GO:0060284,GO:0060341,GO:0060548,GO:0060627,GO:0060840,GO:0060976,GO:0061900,GO:0065007,GO:0065009,GO:0070201,GO:0070325,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072358,GO:0072359,GO:0080090,GO:0090087,GO:0097242,GO:0097367,GO:0097447,GO:0097458,GO:0097708,GO:0098588,GO:0098590,GO:0098657,GO:0098796,GO:0098797,GO:0098805,GO:0120025,GO:0120035,GO:0120038,GO:1900221,GO:1900223,GO:1901214,GO:1901215,GO:1901360,GO:1901615,GO:1901652,GO:1901653,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902652,GO:1903053,GO:1903076,GO:1903078,GO:1903362,GO:1903364,GO:1903827,GO:1903829,GO:1904350,GO:1904352,GO:1904375,GO:1904377,GO:1904645,GO:1904646,GO:1904951,GO:1905165,GO:1905167,GO:1905475,GO:1905477,GO:1905952,GO:1905954,GO:2000026,GO:2000145,GO:2000146,GO:2000586,GO:2000587 - 0.00005253 56.0
CMS2_k127_6558337_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 511.0
CMS2_k127_6566062_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 362.0
CMS2_k127_6566062_1 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000001335 165.0
CMS2_k127_6566062_2 Integral membrane protein DUF106 - - - 0.0000000001939 67.0
CMS2_k127_6581566_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000006464 205.0
CMS2_k127_6581566_1 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000001414 176.0
CMS2_k127_6581566_2 PFAM PQQ enzyme repeat - - - 0.000000000000000000000000000000000004376 146.0
CMS2_k127_6581566_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.000000000000000000000000000000001676 137.0
CMS2_k127_6581566_4 membrane K09790 - - 0.00000000000000000000000000000008603 128.0
CMS2_k127_6581566_5 6-phosphogluconolactonase activity - - - 0.000000000000000000000003942 119.0
CMS2_k127_6581566_6 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.00000000000000004066 96.0
CMS2_k127_6601936_0 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 289.0
CMS2_k127_6601936_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000007642 161.0
CMS2_k127_6601936_2 amine dehydrogenase activity - - - 0.000003089 61.0
CMS2_k127_6601936_3 membrane-associated protein domain - - - 0.00001479 50.0
CMS2_k127_6621647_0 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000001215 200.0
CMS2_k127_6659572_0 tRNA (uracil) methyltransferase activity K10770 GO:0000049,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008198,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016491,GO:0016604,GO:0016705,GO:0016706,GO:0016740,GO:0016741,GO:0030488,GO:0031974,GO:0031981,GO:0032259,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051213,GO:0051716,GO:0055114,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.229 0.000000000001734 75.0
CMS2_k127_6671180_0 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000003716 151.0
CMS2_k127_6671180_1 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.000000000000000000000000000001561 123.0
CMS2_k127_6671180_2 - - - - 0.00000000000001763 79.0
CMS2_k127_6688103_0 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 316.0
CMS2_k127_6688103_1 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000008873 194.0
CMS2_k127_6692291_0 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003635 282.0
CMS2_k127_6692291_1 belongs to the glycosyl hydrolase 13 family K01176,K01208 - 3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000004785 136.0
CMS2_k127_6692291_2 lactoylglutathione lyase activity - - - 0.00000000000000697 79.0
CMS2_k127_6700790_0 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000657 164.0
CMS2_k127_6700790_1 Glyco_18 K01183 - 3.2.1.14 0.000000000000000000000001215 118.0
CMS2_k127_6700790_2 Periplasmic copper-binding protein (NosD) - - - 0.0000000006372 71.0
CMS2_k127_6704584_0 CarboxypepD_reg-like domain K13276,K17734 - - 0.00000000000000000000000000000001407 148.0
CMS2_k127_6704584_1 Subtilase family - - - 0.0000000000001273 85.0
CMS2_k127_6704584_2 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.000000001202 66.0
CMS2_k127_6704584_3 Evidence 5 No homology to any previously reported sequences - - - 0.000007687 60.0
CMS2_k127_67257_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 393.0
CMS2_k127_67257_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 372.0
CMS2_k127_67257_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006538 269.0
CMS2_k127_67257_3 Leucyl aminopeptidase K19701 - 3.4.11.10,3.4.11.6 0.0000000000000000001122 102.0
CMS2_k127_6726971_0 Dehydrogenase K00074 - 1.1.1.157 2.915e-201 647.0
CMS2_k127_6726971_1 YoaP-like - - - 0.00001726 51.0
CMS2_k127_6734906_0 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000007141 168.0
CMS2_k127_6734906_1 PFAM Nitroreductase - - - 0.0000000000001313 83.0
CMS2_k127_6734906_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000005742 65.0
CMS2_k127_6734906_3 transposition - - - 0.0009538 45.0
CMS2_k127_6742256_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 468.0
CMS2_k127_6742256_1 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 301.0
CMS2_k127_6742256_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001569 269.0
CMS2_k127_6742256_3 PFAM SOUL heme-binding protein - - - 0.000000000000000000000000000000000000007754 151.0
CMS2_k127_6747596_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 3.33e-218 698.0
CMS2_k127_6747596_1 Peptidase family C25, C terminal ig-like domain K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.0002882 52.0
CMS2_k127_6765510_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 445.0
CMS2_k127_6765510_1 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001686 269.0
CMS2_k127_6765510_2 - - - - 0.000006353 50.0
CMS2_k127_6765510_3 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0001938 48.0
CMS2_k127_6766155_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 486.0
CMS2_k127_6766155_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 309.0
CMS2_k127_6766155_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000001943 228.0
CMS2_k127_6766155_3 SMART Transcription regulator, AsnC-type - - - 0.0000000000000000000000000000000000002111 145.0
CMS2_k127_6766155_4 SMART regulatory protein AsnC Lrp family K22225 - - 0.00000000000000000000000000001596 123.0
CMS2_k127_6766155_5 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000002439 101.0
CMS2_k127_6766155_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000001282 93.0
CMS2_k127_6767795_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000001479 177.0
CMS2_k127_6767795_1 - - - - 0.0000000000000001183 87.0
CMS2_k127_6779134_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0000000003052 68.0
CMS2_k127_6799836_0 phage tail tape measure protein - - - 0.0000000000000000000006294 111.0
CMS2_k127_6805703_0 phosphoesterase RecJ domain protein - - - 0.0000000000000000001926 96.0
CMS2_k127_6818002_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 467.0
CMS2_k127_6818002_1 Beta-Casp domain K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 463.0
CMS2_k127_6822224_0 Histone H2B K11251,K11252,K11254 GO:0000003,GO:0000228,GO:0000785,GO:0000786,GO:0000788,GO:0000790,GO:0001530,GO:0001906,GO:0001959,GO:0001960,GO:0002227,GO:0002251,GO:0002376,GO:0002385,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005829,GO:0005886,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006337,GO:0006338,GO:0006508,GO:0006807,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006959,GO:0006996,GO:0006997,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007289,GO:0008150,GO:0008152,GO:0008289,GO:0009605,GO:0009607,GO:0009617,GO:0009966,GO:0009968,GO:0009987,GO:0010467,GO:0010646,GO:0010648,GO:0010803,GO:0010804,GO:0016020,GO:0016043,GO:0016477,GO:0016485,GO:0019538,GO:0019730,GO:0019731,GO:0019897,GO:0019898,GO:0019953,GO:0022411,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023057,GO:0030154,GO:0031497,GO:0031498,GO:0031638,GO:0031639,GO:0031640,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032984,GO:0032986,GO:0032991,GO:0032993,GO:0034622,GO:0034728,GO:0035092,GO:0035093,GO:0035821,GO:0040011,GO:0042393,GO:0042742,GO:0042802,GO:0043044,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043486,GO:0043933,GO:0044085,GO:0044093,GO:0044238,GO:0044364,GO:0044419,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044459,GO:0044464,GO:0044703,GO:0044815,GO:0045087,GO:0048232,GO:0048468,GO:0048515,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048609,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050794,GO:0050829,GO:0050830,GO:0050896,GO:0050900,GO:0051098,GO:0051099,GO:0051179,GO:0051276,GO:0051604,GO:0051674,GO:0051704,GO:0051707,GO:0060759,GO:0060761,GO:0061844,GO:0065003,GO:0065004,GO:0065007,GO:0065009,GO:0070013,GO:0071103,GO:0071674,GO:0071704,GO:0071824,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098542,GO:1901363,GO:1901564 - 0.00000000000000000000000000000001627 130.0
CMS2_k127_6856272_0 PFAM Radical SAM domain protein K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000001178 223.0
CMS2_k127_6856272_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000001291 177.0
CMS2_k127_6858623_0 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000002764 194.0
CMS2_k127_6859667_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K06987,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000003862 190.0
CMS2_k127_6859667_1 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.000000000000000000003129 97.0
CMS2_k127_6875778_0 COG0681 Signal peptidase I K13280 - 3.4.21.89 0.00000000000000000000000001633 119.0
CMS2_k127_690903_0 - K03561,K12287 - - 0.000000000000000000000000000000005453 141.0
CMS2_k127_6912230_0 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 319.0
CMS2_k127_6912230_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000005453 97.0
CMS2_k127_6914408_0 E3 ubiquitin-protein ligase DTX3L K06058 GO:0000209,GO:0000323,GO:0002230,GO:0002682,GO:0002697,GO:0002831,GO:0003674,GO:0003824,GO:0004842,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005773,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006282,GO:0006302,GO:0006325,GO:0006355,GO:0006464,GO:0006508,GO:0006511,GO:0006513,GO:0006725,GO:0006807,GO:0006810,GO:0006950,GO:0006974,GO:0006996,GO:0007034,GO:0007041,GO:0008047,GO:0008150,GO:0008152,GO:0008333,GO:0009056,GO:0009057,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010390,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010628,GO:0016043,GO:0016192,GO:0016567,GO:0016569,GO:0016570,GO:0016574,GO:0016740,GO:0019219,GO:0019222,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0030163,GO:0030234,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031347,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031974,GO:0031981,GO:0032092,GO:0032101,GO:0032268,GO:0032269,GO:0032446,GO:0032879,GO:0032880,GO:0032991,GO:0033522,GO:0033523,GO:0033554,GO:0034641,GO:0035561,GO:0035563,GO:0036211,GO:0042393,GO:0043085,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0043412,GO:0043632,GO:0043900,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045739,GO:0045893,GO:0045935,GO:0046483,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050688,GO:0050691,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051098,GO:0051099,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051276,GO:0051338,GO:0051340,GO:0051347,GO:0051348,GO:0051352,GO:0051438,GO:0051444,GO:0051603,GO:0051641,GO:0051649,GO:0051716,GO:0051865,GO:0060255,GO:0060341,GO:0065007,GO:0065009,GO:0070013,GO:0070647,GO:0070936,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097677,GO:0098772,GO:0140096,GO:1900180,GO:1900182,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901664,GO:1901666,GO:1902680,GO:1902965,GO:1902966,GO:1903320,GO:1903321,GO:1903506,GO:1903508,GO:1903827,GO:1903829,GO:1905666,GO:1905668,GO:2000112,GO:2000644,GO:2000646,GO:2000779,GO:2000781,GO:2001020,GO:2001022,GO:2001032,GO:2001034,GO:2001141 2.3.2.27 0.000001394 57.0
CMS2_k127_6915466_0 Rad51 - - - 0.000000000000000000000000000000000000000000000001168 179.0
CMS2_k127_6915466_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000001753 57.0
CMS2_k127_6920057_0 - K03561,K12287 - - 0.0000003727 63.0
CMS2_k127_6920057_1 Bacterial Ig-like domain (group 3) - - - 0.0002929 53.0
CMS2_k127_6927607_0 TatD related DNase K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002063 254.0
CMS2_k127_6927607_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000005836 88.0
CMS2_k127_6962323_0 PQQ-like domain K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000000000000000000000004996 175.0
CMS2_k127_6962323_1 regulation of store-operated calcium entry - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0010959,GO:0012505,GO:0016020,GO:0016021,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0032879,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043269,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0050789,GO:0051049,GO:0051924,GO:0065007,GO:0098827,GO:2001256 - 0.000000000001823 79.0
CMS2_k127_6963800_0 Protein heterodimerization activity K11252,K11253,K11254 - - 0.0000000000000000000000000003975 120.0
CMS2_k127_6963800_1 Histone H2A K11251 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044424,GO:0044464 - 0.000000000000000000108 94.0
CMS2_k127_6966524_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 407.0
CMS2_k127_6968564_0 Pyridine nucleotide-disulphide oxidoreductase - - - 7.987e-298 949.0
CMS2_k127_6969587_0 Psort location CytoplasmicMembrane, score - - - 0.00005093 55.0
CMS2_k127_6973544_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000005148 66.0
CMS2_k127_6983660_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.327e-201 637.0
CMS2_k127_6983660_1 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.0000000000000000000000000000000000000000000000000006868 188.0
CMS2_k127_6983660_2 TIGRFAM bacteriochlorophyll chlorophyll synthetase K04040 - 2.5.1.133,2.5.1.62 0.000001383 59.0
CMS2_k127_6985879_0 CBS domain K03498 - - 0.00000000000000000000000000000000000000000000000000004655 207.0
CMS2_k127_6985879_1 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.00000000000000000516 97.0
CMS2_k127_699186_0 Zn_pept - - - 0.000002638 59.0
CMS2_k127_7002162_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.00000485 61.0
CMS2_k127_7002162_1 Leucine rich repeat - - - 0.00007066 54.0
CMS2_k127_7009534_0 - - - - 0.00000000000000002172 89.0
CMS2_k127_7009534_1 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.000000002245 66.0
CMS2_k127_7016858_0 - K03561,K12287 - - 0.00000000000000000000000000000000000000000005508 177.0
CMS2_k127_7029815_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 381.0
CMS2_k127_7031796_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004507 269.0
CMS2_k127_7031796_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001023 255.0
CMS2_k127_7031796_2 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000001641 111.0
CMS2_k127_7031796_3 Co Zn Cd efflux system component K16264 - - 0.0000000000000000001967 92.0
CMS2_k127_7031796_4 sequence-specific DNA binding K07108 - - 0.00000000000001871 77.0
CMS2_k127_7031796_5 Domain of unknown function (DUF5122) beta-propeller K21449 - - 0.000005085 57.0
CMS2_k127_7031796_6 Belongs to the peptidase S8 family - - - 0.0001534 52.0
CMS2_k127_7049934_0 Thrombospondin type 1 repeats - GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0030029,GO:0030036,GO:0031532,GO:0042995,GO:0044464,GO:0071840,GO:0071944,GO:0098846,GO:0120025 - 0.000000005482 62.0
CMS2_k127_7051680_0 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000008208 213.0
CMS2_k127_7051680_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000005113 113.0
CMS2_k127_7051680_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000003383 67.0
CMS2_k127_7052090_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000001541 239.0
CMS2_k127_7052090_1 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000008463 129.0
CMS2_k127_7085808_0 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 573.0
CMS2_k127_7085808_1 Putative Phosphatase K01079 - 3.1.3.3 0.00002514 51.0
CMS2_k127_728800_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 6.702e-216 684.0
CMS2_k127_728800_1 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 337.0
CMS2_k127_728800_2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 334.0
CMS2_k127_728800_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 296.0
CMS2_k127_728800_4 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 301.0
CMS2_k127_728800_5 Conserved hypothetical ATP binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000002754 235.0
CMS2_k127_728800_6 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.0000000000000000000000000000000000000000000000000000000000000001055 231.0
CMS2_k127_728800_7 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000001634 220.0
CMS2_k127_728800_8 - - - - 0.000000000000004009 80.0
CMS2_k127_75137_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 430.0
CMS2_k127_75137_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 406.0
CMS2_k127_75137_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006619 277.0
CMS2_k127_75137_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000002184 223.0
CMS2_k127_75137_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000003816 198.0
CMS2_k127_75137_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000002666 182.0
CMS2_k127_75137_6 Bifunctional inositol-1 monophosphatase fructose-1,6-bisphosphatase K01092 - 3.1.3.25 0.0001754 45.0
CMS2_k127_77939_0 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000004316 173.0
CMS2_k127_77939_1 - K16905,K16906 - - 0.000000000000000000000000000005793 130.0
CMS2_k127_77939_2 transmembrane transport K01992 - - 0.00000000000000000000003562 108.0
CMS2_k127_77939_3 Phosphate-starvation-inducible E - - - 0.00000000000001351 79.0
CMS2_k127_77939_4 glucosylceramidase activity - - - 0.000000002064 63.0
CMS2_k127_779759_0 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007221 254.0
CMS2_k127_784573_0 geranylgeranyl reductase activity K10960,K17830 - 1.3.1.101,1.3.1.111,1.3.1.83,1.3.7.11 0.000000000000000000002043 107.0
CMS2_k127_784573_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000009776 70.0
CMS2_k127_798162_0 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000174 127.0
CMS2_k127_798162_1 Acyl-protein synthetase, LuxE - - - 0.000000000000000000002074 107.0
CMS2_k127_798162_2 FAD linked oxidase domain protein - - - 0.00000000000000002899 87.0
CMS2_k127_798722_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 7.925e-321 996.0
CMS2_k127_798722_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000006744 231.0
CMS2_k127_798722_2 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000887 218.0
CMS2_k127_798722_3 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 0.00000000000000000000000000000000000000001019 160.0
CMS2_k127_811528_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 416.0
CMS2_k127_811528_1 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 370.0
CMS2_k127_811528_2 TIGRFAM ribosomal RNA small subunit methyltransferase RsmB K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 348.0
CMS2_k127_811528_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.000000000000000000009509 93.0
CMS2_k127_837797_0 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000000000552 104.0
CMS2_k127_837797_1 TOPRIM - - - 0.00000000000000004168 86.0
CMS2_k127_837797_2 Belongs to the UPF0235 family K09131 - - 0.0000000000000005566 83.0
CMS2_k127_846013_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 381.0
CMS2_k127_846013_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000005103 243.0
CMS2_k127_846013_2 HTH-type transcriptional regulatory protein K07728 - - 0.000000000000000000000000000000000000000000000000000000000000008073 227.0
CMS2_k127_846013_3 CrtC N-terminal lipocalin domain - - - 0.0000000000000000005553 100.0
CMS2_k127_863695_0 Peptidase family C25 - - - 0.00000000001585 76.0
CMS2_k127_863695_1 PFAM regulatory protein AsnC Lrp family K03718 - - 0.00001345 52.0
CMS2_k127_867514_0 FMN binding - - - 2.166e-245 766.0
CMS2_k127_867514_1 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 299.0
CMS2_k127_867514_2 Pyridine nucleotide-disulphide oxidoreductase K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000001124 232.0
CMS2_k127_867514_3 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000007535 164.0
CMS2_k127_876629_0 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000005534 223.0
CMS2_k127_876629_1 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.0000000000000000000000000004749 125.0
CMS2_k127_87697_0 Domain of unknown function (DUF4842) - - - 0.0008618 53.0
CMS2_k127_885028_0 Alpha beta hydrolase - - - 0.0000000000000000007971 98.0
CMS2_k127_886311_0 capsid protein - - - 0.00000000000000000000000000000000000000000000000000000000000881 224.0
CMS2_k127_886311_1 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.000000000000000000000000000000000000004076 149.0
CMS2_k127_886311_2 Caudovirus prohead serine protease K06904 - - 0.000000000000000000000000007419 124.0
CMS2_k127_886311_3 Phage portal protein - - - 0.00000000000000000002951 100.0
CMS2_k127_886311_5 domain protein - - - 0.0002297 54.0
CMS2_k127_934422_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 491.0
CMS2_k127_934422_1 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001415 243.0
CMS2_k127_934422_2 archaeal coiled-coil protein - - - 0.000000000000000000000008754 112.0
CMS2_k127_947903_0 Protein of unknown function (DUF3522) - - - 0.0002828 52.0
CMS2_k127_94803_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 317.0
CMS2_k127_94803_1 Aminotransferase class-III K03918,K13524 - 2.6.1.19,2.6.1.22,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000001883 228.0
CMS2_k127_954620_0 Histone H2A K11251 - - 0.0000000000000002948 85.0
CMS2_k127_954620_1 Belongs to the SKP1 family K03094 - - 0.000000001387 65.0
CMS2_k127_955213_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000003897 213.0
CMS2_k127_984421_0 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.00000000000000000000003532 109.0
CMS2_k127_984979_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 422.0
CMS2_k127_984979_1 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000005715 189.0
CMS2_k127_984979_2 NAD(P)H-binding - - - 0.0000000001133 63.0