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Overview

ID MAG00457
Name CMS2_bin.70
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus Quisquiliibacterium
Species Quisquiliibacterium sp036525975
Assembly information
Completeness (%) 95.77
Contamination (%) 0.48
GC content (%) 71.0
N50 (bp) 37,433
Genome size (bp) 3,232,317

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3015

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1101937_0 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 577.0
CMS2_k127_1101937_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 578.0
CMS2_k127_1101937_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000001763 133.0
CMS2_k127_1101937_11 Acetyltransferase (GNAT) family - - - 0.000000001043 67.0
CMS2_k127_1101937_2 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 524.0
CMS2_k127_1101937_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 471.0
CMS2_k127_1101937_4 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 361.0
CMS2_k127_1101937_5 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 292.0
CMS2_k127_1101937_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006485 248.0
CMS2_k127_1101937_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007426 241.0
CMS2_k127_1101937_8 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000001312 199.0
CMS2_k127_1101937_9 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000285 182.0
CMS2_k127_117520_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 589.0
CMS2_k127_117520_1 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007334 307.0
CMS2_k127_117520_2 TIGRFAM TIGR00268 family protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009859 275.0
CMS2_k127_117520_3 Lysozyme inhibitor LprI - - - 0.00000000000000000000000000000000000000000000000000000000001284 218.0
CMS2_k127_117520_4 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000352 223.0
CMS2_k127_117520_5 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000579 68.0
CMS2_k127_117520_6 Amino acid adenylation domain - - - 0.0000002796 60.0
CMS2_k127_117520_7 Lysozyme inhibitor LprI - - - 0.00006424 50.0
CMS2_k127_117520_8 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00007875 48.0
CMS2_k127_1202237_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1071.0
CMS2_k127_1202237_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.038e-266 831.0
CMS2_k127_1202237_10 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - 0.00000000000000000000000000000000000000000000000000000000337 212.0
CMS2_k127_1202237_11 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000005813 193.0
CMS2_k127_1202237_12 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000001231 143.0
CMS2_k127_1202237_13 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000008318 119.0
CMS2_k127_1202237_14 3-hydroxyacyl-CoA dehydrogenase - - - 0.0000000000000005566 83.0
CMS2_k127_1202237_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.022e-218 682.0
CMS2_k127_1202237_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 580.0
CMS2_k127_1202237_4 PFAM NUDIX hydrolase K07455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 587.0
CMS2_k127_1202237_5 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 362.0
CMS2_k127_1202237_6 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 332.0
CMS2_k127_1202237_7 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 308.0
CMS2_k127_1202237_8 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 333.0
CMS2_k127_1202237_9 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003028 284.0
CMS2_k127_1209611_0 FAD linked oxidase domain protein - - - 0.0 1937.0
CMS2_k127_1209611_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 3.907e-249 776.0
CMS2_k127_1209611_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 318.0
CMS2_k127_1209611_11 mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 331.0
CMS2_k127_1209611_12 Histidine kinase K20975 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 322.0
CMS2_k127_1209611_13 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 303.0
CMS2_k127_1209611_14 import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002341 257.0
CMS2_k127_1209611_15 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007113 238.0
CMS2_k127_1209611_16 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000009562 247.0
CMS2_k127_1209611_17 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001146 225.0
CMS2_k127_1209611_18 effector of murein hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000006256 233.0
CMS2_k127_1209611_19 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.000000000000000000000000000000000000000000000000000000002536 209.0
CMS2_k127_1209611_2 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 2.539e-208 655.0
CMS2_k127_1209611_20 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000002125 189.0
CMS2_k127_1209611_21 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000004451 180.0
CMS2_k127_1209611_22 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000000000000000000000000000000000000000000003323 169.0
CMS2_k127_1209611_23 Transcriptional regulator K07734 - - 0.000000000000000000000000000000000000000000003865 180.0
CMS2_k127_1209611_24 MaoC like domain - - - 0.00000000000000000000000000000000000000146 152.0
CMS2_k127_1209611_25 nuclease - - - 0.000000000000000000000000000000000000008565 154.0
CMS2_k127_1209611_26 response regulator K02479,K07684 - - 0.000000000000000000000000000000000002224 145.0
CMS2_k127_1209611_27 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000002349 144.0
CMS2_k127_1209611_28 ubiquinone biosynthetic process from chorismate K03690 GO:0006082,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0019752,GO:0032150,GO:0042180,GO:0042181,GO:0043436,GO:0043648,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046417,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000009399 113.0
CMS2_k127_1209611_29 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a K06518 - - 0.000000000000000000004871 99.0
CMS2_k127_1209611_3 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 582.0
CMS2_k127_1209611_30 - - - - 0.00003333 55.0
CMS2_k127_1209611_4 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 555.0
CMS2_k127_1209611_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 523.0
CMS2_k127_1209611_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 491.0
CMS2_k127_1209611_7 C4-dicarboxylate ABC transporter K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 481.0
CMS2_k127_1209611_8 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 387.0
CMS2_k127_1209611_9 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 359.0
CMS2_k127_1243128_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2522.0
CMS2_k127_1243128_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1427.0
CMS2_k127_1243128_10 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 384.0
CMS2_k127_1243128_11 cytochrome C oxidase K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 326.0
CMS2_k127_1243128_12 dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 330.0
CMS2_k127_1243128_13 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 311.0
CMS2_k127_1243128_14 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000007831 235.0
CMS2_k127_1243128_15 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000002266 197.0
CMS2_k127_1243128_16 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000053 205.0
CMS2_k127_1243128_17 MaoC like domain - - - 0.00000000000000000000000000000000000000000000001693 184.0
CMS2_k127_1243128_18 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000944 167.0
CMS2_k127_1243128_19 PFAM RNA-binding S4 domain protein K04762 - - 0.00000000000000000000000000000000000495 142.0
CMS2_k127_1243128_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 2.681e-275 854.0
CMS2_k127_1243128_20 FixH family K09926 - - 0.0000000000000000000000006102 121.0
CMS2_k127_1243128_21 - - - - 0.000000000004961 69.0
CMS2_k127_1243128_22 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.0000000003029 70.0
CMS2_k127_1243128_23 Cytochrome oxidase maturation protein cbb3-type - - - 0.000000001037 72.0
CMS2_k127_1243128_3 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 1.325e-245 767.0
CMS2_k127_1243128_4 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 1.374e-211 701.0
CMS2_k127_1243128_5 cytochrome C oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 622.0
CMS2_k127_1243128_6 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 515.0
CMS2_k127_1243128_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 492.0
CMS2_k127_1243128_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 442.0
CMS2_k127_1243128_9 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009678 399.0
CMS2_k127_1324117_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1710.0
CMS2_k127_1324117_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 1.333e-291 901.0
CMS2_k127_1324117_10 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 519.0
CMS2_k127_1324117_11 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 551.0
CMS2_k127_1324117_12 Catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 508.0
CMS2_k127_1324117_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 481.0
CMS2_k127_1324117_14 luciferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 469.0
CMS2_k127_1324117_15 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 465.0
CMS2_k127_1324117_16 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 445.0
CMS2_k127_1324117_17 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 443.0
CMS2_k127_1324117_18 HMGL-like K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 415.0
CMS2_k127_1324117_19 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 421.0
CMS2_k127_1324117_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 9.658e-289 897.0
CMS2_k127_1324117_20 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 411.0
CMS2_k127_1324117_21 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 381.0
CMS2_k127_1324117_22 ABC transporter K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 352.0
CMS2_k127_1324117_23 Succinylglutamate desuccinylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 350.0
CMS2_k127_1324117_24 belongs to the bacterial solute-binding protein 3 family K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 324.0
CMS2_k127_1324117_25 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 339.0
CMS2_k127_1324117_26 Asp/Glu/Hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 326.0
CMS2_k127_1324117_27 PFAM Enoyl-CoA hydratase isomerase K13766,K15312 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 312.0
CMS2_k127_1324117_28 deiminase K05603 - 3.5.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 312.0
CMS2_k127_1324117_29 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 311.0
CMS2_k127_1324117_3 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 1.916e-288 900.0
CMS2_k127_1324117_30 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 294.0
CMS2_k127_1324117_31 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 294.0
CMS2_k127_1324117_32 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001842 272.0
CMS2_k127_1324117_33 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000003361 271.0
CMS2_k127_1324117_34 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001842 273.0
CMS2_k127_1324117_35 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001538 246.0
CMS2_k127_1324117_36 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000003334 234.0
CMS2_k127_1324117_37 COG1247 Sortase and related acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000002601 222.0
CMS2_k127_1324117_38 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000004196 227.0
CMS2_k127_1324117_39 UTRA K05836 - - 0.00000000000000000000000000000000000000000000000000000000188 213.0
CMS2_k127_1324117_4 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 4.809e-266 834.0
CMS2_k127_1324117_40 YsiA-like protein, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000002468 195.0
CMS2_k127_1324117_41 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000004086 196.0
CMS2_k127_1324117_42 LysE type translocator - - - 0.00000000000000000000000000000000000000001862 163.0
CMS2_k127_1324117_43 Protein of unknown function (DUF2783) - - - 0.000000000000000000003435 101.0
CMS2_k127_1324117_44 HutD K09975 - - 0.000000000000001513 85.0
CMS2_k127_1324117_45 - - - - 0.000000000008993 76.0
CMS2_k127_1324117_46 Protein of unknown function (DUF1289) K06938 - - 0.0000000000186 76.0
CMS2_k127_1324117_47 PIN domain - - - 0.00000006543 57.0
CMS2_k127_1324117_5 FAD binding domain K05712 - 1.14.13.127 4.605e-246 771.0
CMS2_k127_1324117_6 COG0044 Dihydroorotase and related cyclic amidohydrolases - - - 5.326e-199 631.0
CMS2_k127_1324117_7 Periplasmic binding protein K01999 - - 2.943e-197 625.0
CMS2_k127_1324117_8 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 590.0
CMS2_k127_1324117_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 551.0
CMS2_k127_1413794_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1326.0
CMS2_k127_1413794_1 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 1.311e-249 788.0
CMS2_k127_1413794_10 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000000001055 201.0
CMS2_k127_1413794_11 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.0000000000000000000000000000000000000000000000001461 181.0
CMS2_k127_1413794_12 - - - - 0.00000000000000000000000000000000000000000000139 184.0
CMS2_k127_1413794_13 MltA-interacting protein MipA - - - 0.000000000000000000000000000000000000000000008805 173.0
CMS2_k127_1413794_14 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000001545 166.0
CMS2_k127_1413794_2 Methylmalonyl-CoA mutase K01848 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.4.99.2 3.235e-247 775.0
CMS2_k127_1413794_3 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 1.648e-231 729.0
CMS2_k127_1413794_4 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 615.0
CMS2_k127_1413794_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 361.0
CMS2_k127_1413794_6 Beta-lactamase K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 350.0
CMS2_k127_1413794_7 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 321.0
CMS2_k127_1413794_8 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005209 299.0
CMS2_k127_1413794_9 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 277.0
CMS2_k127_1460419_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 1.819e-314 990.0
CMS2_k127_1460419_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 4.864e-200 628.0
CMS2_k127_1460419_10 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 322.0
CMS2_k127_1460419_11 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004222 259.0
CMS2_k127_1460419_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000006565 251.0
CMS2_k127_1460419_13 dna polymerase iii K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000004939 235.0
CMS2_k127_1460419_14 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000001746 220.0
CMS2_k127_1460419_15 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000002104 158.0
CMS2_k127_1460419_16 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000005402 132.0
CMS2_k127_1460419_17 PilZ domain K02676 - - 0.00000000000000000000000009602 122.0
CMS2_k127_1460419_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 431.0
CMS2_k127_1460419_3 hydrolase activity, acting on ester bonds K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 382.0
CMS2_k127_1460419_4 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 367.0
CMS2_k127_1460419_5 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 355.0
CMS2_k127_1460419_6 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 359.0
CMS2_k127_1460419_7 Class II aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 365.0
CMS2_k127_1460419_8 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 342.0
CMS2_k127_1460419_9 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 329.0
CMS2_k127_16489_0 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 600.0
CMS2_k127_16489_1 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 533.0
CMS2_k127_16489_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 454.0
CMS2_k127_16489_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 298.0
CMS2_k127_165506_0 Dehydrogenase K00382 - 1.8.1.4 5.17e-285 885.0
CMS2_k127_1739605_0 dna topoisomerase III K03169 - 5.99.1.2 0.0 1243.0
CMS2_k127_1739605_1 amp-dependent synthetase and ligase - - - 1.78e-292 931.0
CMS2_k127_1739605_10 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 351.0
CMS2_k127_1739605_11 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 345.0
CMS2_k127_1739605_12 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 328.0
CMS2_k127_1739605_13 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 339.0
CMS2_k127_1739605_14 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 295.0
CMS2_k127_1739605_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000006675 254.0
CMS2_k127_1739605_16 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004036 239.0
CMS2_k127_1739605_17 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000225 202.0
CMS2_k127_1739605_18 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000003633 132.0
CMS2_k127_1739605_19 -Thioesterase K01075 - 3.1.2.23 0.00000000000000000000000000001807 124.0
CMS2_k127_1739605_2 Histidine kinase - - - 2.365e-233 745.0
CMS2_k127_1739605_20 - - - - 0.0000000000000000000000000003351 118.0
CMS2_k127_1739605_21 Protein of unknown function (DUF3567) - - - 0.000000000000000000000000002246 115.0
CMS2_k127_1739605_3 COG0569 K transport systems, NAD-binding component K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 590.0
CMS2_k127_1739605_4 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 544.0
CMS2_k127_1739605_5 Putative Na+/H+ antiporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 544.0
CMS2_k127_1739605_6 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 488.0
CMS2_k127_1739605_7 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 448.0
CMS2_k127_1739605_8 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 380.0
CMS2_k127_1739605_9 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 355.0
CMS2_k127_183678_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1686.0
CMS2_k127_183678_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1024.0
CMS2_k127_183678_10 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 4.788e-201 634.0
CMS2_k127_183678_11 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 7.277e-194 630.0
CMS2_k127_183678_12 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 610.0
CMS2_k127_183678_13 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 595.0
CMS2_k127_183678_14 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 589.0
CMS2_k127_183678_15 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 593.0
CMS2_k127_183678_16 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 538.0
CMS2_k127_183678_17 Benzoate membrane transport protein K05782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 524.0
CMS2_k127_183678_18 Mg chelatase subunit ChlI K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 527.0
CMS2_k127_183678_19 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 522.0
CMS2_k127_183678_2 abc transporter K06020 - 3.6.3.25 1.891e-299 925.0
CMS2_k127_183678_20 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 522.0
CMS2_k127_183678_21 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 511.0
CMS2_k127_183678_22 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 507.0
CMS2_k127_183678_23 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 499.0
CMS2_k127_183678_24 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 490.0
CMS2_k127_183678_25 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 481.0
CMS2_k127_183678_26 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 477.0
CMS2_k127_183678_27 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 490.0
CMS2_k127_183678_28 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 480.0
CMS2_k127_183678_29 PFAM peptidase S58 DmpA K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 469.0
CMS2_k127_183678_3 Cysteine-rich domain - - - 1.247e-275 853.0
CMS2_k127_183678_30 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 451.0
CMS2_k127_183678_31 PFAM 4Fe-4S K00184,K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 454.0
CMS2_k127_183678_32 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 421.0
CMS2_k127_183678_33 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 406.0
CMS2_k127_183678_34 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 386.0
CMS2_k127_183678_35 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 374.0
CMS2_k127_183678_36 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 352.0
CMS2_k127_183678_37 PFAM aldo keto reductase - GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009898 350.0
CMS2_k127_183678_38 Protein of unknown function (DUF3179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 354.0
CMS2_k127_183678_39 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 342.0
CMS2_k127_183678_4 ABC transporter K06147,K18893 - - 5.513e-244 768.0
CMS2_k127_183678_40 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 336.0
CMS2_k127_183678_41 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 329.0
CMS2_k127_183678_42 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 316.0
CMS2_k127_183678_43 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 341.0
CMS2_k127_183678_44 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 322.0
CMS2_k127_183678_45 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 307.0
CMS2_k127_183678_46 CoA-transferase family III K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001374 307.0
CMS2_k127_183678_47 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005214 283.0
CMS2_k127_183678_48 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008903 275.0
CMS2_k127_183678_49 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006376 254.0
CMS2_k127_183678_5 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.196e-233 728.0
CMS2_k127_183678_50 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001535 273.0
CMS2_k127_183678_51 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002113 267.0
CMS2_k127_183678_52 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000009818 232.0
CMS2_k127_183678_53 Bacterial regulatory proteins, luxR family K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000005918 248.0
CMS2_k127_183678_54 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000002919 238.0
CMS2_k127_183678_55 - - - - 0.000000000000000000000000000000000000000000000000000000000000009332 235.0
CMS2_k127_183678_56 DsrE/DsrF-like family K07235 - - 0.00000000000000000000000000000000000000000000000000000000000004979 214.0
CMS2_k127_183678_57 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000000000005178 213.0
CMS2_k127_183678_58 YaeQ family - - - 0.000000000000000000000000000000000000000000000000000000000001504 216.0
CMS2_k127_183678_59 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000001499 213.0
CMS2_k127_183678_6 Ammonium Transporter Family K03320 - - 3.527e-221 696.0
CMS2_k127_183678_60 [2Fe-2S] binding domain K18029 - 1.17.2.1 0.0000000000000000000000000000000000000000000000000000000006127 206.0
CMS2_k127_183678_61 Cupin 2, conserved barrel domain protein K00450,K00971,K09988,K11312 - 1.13.11.4,2.7.7.13,5.3.1.15 0.00000000000000000000000000000000000000000000000000000003701 203.0
CMS2_k127_183678_62 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000005258 213.0
CMS2_k127_183678_63 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000003094 194.0
CMS2_k127_183678_64 Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000000000000005006 196.0
CMS2_k127_183678_65 DsrE/DsrF-like family K07236 - - 0.0000000000000000000000000000000000000000000000000001294 192.0
CMS2_k127_183678_66 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000000000000001403 194.0
CMS2_k127_183678_67 - - - - 0.00000000000000000000000000000000000000000001516 168.0
CMS2_k127_183678_68 DsrC like protein - - - 0.000000000000000000000000000000000000000005514 156.0
CMS2_k127_183678_69 protein conserved in bacteria K09790 - - 0.0000000000000000000000000000000000006069 144.0
CMS2_k127_183678_7 Highly conserved protein containing a thioredoxin domain K06888 - - 3.264e-215 714.0
CMS2_k127_183678_70 Uncharacterised protein family (UPF0149) K07039 - - 0.000000000000000000000000000000000001442 159.0
CMS2_k127_183678_71 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.000000000000000000000000000000000004735 141.0
CMS2_k127_183678_72 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000001939 138.0
CMS2_k127_183678_73 Peptidase S24-like - - - 0.000000000000000000000000000000001553 136.0
CMS2_k127_183678_74 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000001669 122.0
CMS2_k127_183678_75 DsrH like protein K07237 - - 0.0000000000000000000000000001251 117.0
CMS2_k127_183678_76 - - - - 0.0000000000000000000000000001944 122.0
CMS2_k127_183678_77 phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000005548 113.0
CMS2_k127_183678_78 - - - - 0.000000000000000000000003929 108.0
CMS2_k127_183678_79 - - - - 0.0000000000000000000007096 100.0
CMS2_k127_183678_8 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 1.747e-211 685.0
CMS2_k127_183678_80 TIGRFAM CRISPR-associated protein - - - 0.00000000000000000001604 102.0
CMS2_k127_183678_81 Protein of unknown function (DUF3429) - - - 0.00000000000000000005551 95.0
CMS2_k127_183678_82 Domain of unknown function (DUF1840) - - - 0.0000000000000001001 86.0
CMS2_k127_183678_83 - - - - 0.000000000000001092 81.0
CMS2_k127_183678_84 Belongs to the HesB IscA family K13628 - - 0.00000000000006071 87.0
CMS2_k127_183678_85 Membrane fusogenic activity K09806 - - 0.00000000000315 70.0
CMS2_k127_183678_86 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000005752 71.0
CMS2_k127_183678_87 - - - - 0.0000001111 55.0
CMS2_k127_183678_9 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 2.373e-207 662.0
CMS2_k127_1894538_0 Glycosyl hydrolases family 15 - - - 5.847e-225 713.0
CMS2_k127_1894538_1 PFAM AMP-dependent synthetase and ligase K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 577.0
CMS2_k127_1894538_10 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000005829 178.0
CMS2_k127_1894538_11 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000309 109.0
CMS2_k127_1894538_12 Class II aldolase adducin family protein - - - 0.0000000817 54.0
CMS2_k127_1894538_2 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 559.0
CMS2_k127_1894538_3 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 453.0
CMS2_k127_1894538_4 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 461.0
CMS2_k127_1894538_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002271 292.0
CMS2_k127_1894538_7 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000005222 207.0
CMS2_k127_1894538_8 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000000000000008326 203.0
CMS2_k127_1894538_9 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000001346 196.0
CMS2_k127_190301_0 Belongs to the transketolase family K00615 - 2.2.1.1 1.11e-243 764.0
CMS2_k127_190301_1 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 9.609e-228 730.0
CMS2_k127_190301_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 399.0
CMS2_k127_190301_11 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 384.0
CMS2_k127_190301_12 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 372.0
CMS2_k127_190301_13 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 387.0
CMS2_k127_190301_14 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 389.0
CMS2_k127_190301_15 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 363.0
CMS2_k127_190301_16 ABC transporter substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 345.0
CMS2_k127_190301_17 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 316.0
CMS2_k127_190301_18 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 324.0
CMS2_k127_190301_19 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 307.0
CMS2_k127_190301_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 9.335e-220 691.0
CMS2_k127_190301_20 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001159 257.0
CMS2_k127_190301_21 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000195 258.0
CMS2_k127_190301_22 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000002745 276.0
CMS2_k127_190301_23 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.0000000000000000000000000000000000000000000000000000000000000000003544 237.0
CMS2_k127_190301_24 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001175 238.0
CMS2_k127_190301_25 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000004796 219.0
CMS2_k127_190301_26 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.0000000000000000000000000000000000000000000000002513 178.0
CMS2_k127_190301_27 Dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000005498 162.0
CMS2_k127_190301_28 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.00000000000000000000000000000000000001154 152.0
CMS2_k127_190301_29 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000003569 144.0
CMS2_k127_190301_3 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 1.638e-195 613.0
CMS2_k127_190301_31 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000002569 77.0
CMS2_k127_190301_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 602.0
CMS2_k127_190301_5 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 573.0
CMS2_k127_190301_6 Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 508.0
CMS2_k127_190301_7 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 453.0
CMS2_k127_190301_8 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 457.0
CMS2_k127_190301_9 Carboxylesterase family K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 463.0
CMS2_k127_1908632_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1210.0
CMS2_k127_1908632_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 7.124e-304 942.0
CMS2_k127_1908632_10 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 381.0
CMS2_k127_1908632_11 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 360.0
CMS2_k127_1908632_12 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 356.0
CMS2_k127_1908632_13 short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 351.0
CMS2_k127_1908632_14 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 346.0
CMS2_k127_1908632_15 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 344.0
CMS2_k127_1908632_16 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01856 - 5.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 347.0
CMS2_k127_1908632_17 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 347.0
CMS2_k127_1908632_18 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 319.0
CMS2_k127_1908632_19 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 326.0
CMS2_k127_1908632_2 DNA helicase K03657 - 3.6.4.12 2.753e-302 945.0
CMS2_k127_1908632_20 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 305.0
CMS2_k127_1908632_21 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 298.0
CMS2_k127_1908632_22 Divalent heavy-metal cations transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001653 291.0
CMS2_k127_1908632_23 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002271 274.0
CMS2_k127_1908632_24 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007549 254.0
CMS2_k127_1908632_25 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007702 256.0
CMS2_k127_1908632_26 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000001564 221.0
CMS2_k127_1908632_27 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000004883 209.0
CMS2_k127_1908632_28 - - - - 0.0000000000000000000000000000000000000000006234 167.0
CMS2_k127_1908632_29 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000001187 166.0
CMS2_k127_1908632_3 rieske 2fe-2s K00499 - 1.14.15.7 1.149e-197 624.0
CMS2_k127_1908632_30 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000000000000009547 130.0
CMS2_k127_1908632_31 Isochorismatase family - - - 0.00000000000000000000007116 111.0
CMS2_k127_1908632_32 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000001225 87.0
CMS2_k127_1908632_33 PFAM regulatory protein TetR - - - 0.0000000000000131 78.0
CMS2_k127_1908632_4 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 548.0
CMS2_k127_1908632_5 Mandelate Racemase Muconate Lactonizing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 547.0
CMS2_k127_1908632_6 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 525.0
CMS2_k127_1908632_7 NMT1/THI5 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006759 497.0
CMS2_k127_1908632_8 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 476.0
CMS2_k127_1908632_9 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 402.0
CMS2_k127_1924397_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1710.0
CMS2_k127_1924397_1 DNA polymerase K02337 - 2.7.7.7 0.0 1446.0
CMS2_k127_1924397_10 Peptidase family M20/M25/M40 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 522.0
CMS2_k127_1924397_11 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 484.0
CMS2_k127_1924397_12 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 478.0
CMS2_k127_1924397_13 Pyridoxal-phosphate dependent enzyme K01751 - 4.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 463.0
CMS2_k127_1924397_14 Decaheme c-type cytochrome, DmsE family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 445.0
CMS2_k127_1924397_15 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 456.0
CMS2_k127_1924397_16 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 394.0
CMS2_k127_1924397_17 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 372.0
CMS2_k127_1924397_18 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 376.0
CMS2_k127_1924397_19 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 351.0
CMS2_k127_1924397_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0 1082.0
CMS2_k127_1924397_20 Bacterial transglutaminase-like N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 305.0
CMS2_k127_1924397_21 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 298.0
CMS2_k127_1924397_22 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006369 256.0
CMS2_k127_1924397_23 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000002289 233.0
CMS2_k127_1924397_24 hydrolases of the HAD superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001267 240.0
CMS2_k127_1924397_25 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000001216 218.0
CMS2_k127_1924397_26 Helix-turn-helix domain, rpiR family - - - 0.000000000000000000000000000000000000000000000000000000002345 214.0
CMS2_k127_1924397_27 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.0000000000000000000000000000000000000000000000000000004773 199.0
CMS2_k127_1924397_28 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000001028 190.0
CMS2_k127_1924397_29 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000008823 207.0
CMS2_k127_1924397_3 Circularly permuted ATP-grasp type 2 - - - 1.427e-273 865.0
CMS2_k127_1924397_30 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000003742 184.0
CMS2_k127_1924397_31 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000006349 178.0
CMS2_k127_1924397_32 PFAM Peptidase M11 gametolysin - - - 0.000000000000000000000000000000002961 149.0
CMS2_k127_1924397_33 Cytochrome c K08738 - - 0.000000000000000000000001616 118.0
CMS2_k127_1924397_34 Binding-protein-dependent transport system inner membrane component K02042 - - 0.0000000000001013 71.0
CMS2_k127_1924397_35 Cytochrome c - - - 0.000000001736 66.0
CMS2_k127_1924397_4 Ribonuclease E/G family K08301 - - 3.161e-216 695.0
CMS2_k127_1924397_5 Bacterial protein of unknown function (DUF853) K06915 - - 3.502e-215 684.0
CMS2_k127_1924397_6 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6.718e-204 652.0
CMS2_k127_1924397_7 Belongs to the GARS family K01945 - 6.3.4.13 1.851e-200 634.0
CMS2_k127_1924397_8 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 595.0
CMS2_k127_1924397_9 Carbon-nitrogen hydrolase K01459 - 3.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 509.0
CMS2_k127_192881_0 Peptidase family M3 K01414 - 3.4.24.70 2.271e-292 921.0
CMS2_k127_192881_1 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 4.206e-271 839.0
CMS2_k127_192881_10 Enoyl-CoA hydratase carnithine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 392.0
CMS2_k127_192881_11 pfam abc1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 380.0
CMS2_k127_192881_12 HpcH/HpaI aldolase/citrate lyase family K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 369.0
CMS2_k127_192881_13 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 353.0
CMS2_k127_192881_14 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 334.0
CMS2_k127_192881_15 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000008078 228.0
CMS2_k127_192881_16 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000114 189.0
CMS2_k127_192881_17 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000002673 130.0
CMS2_k127_192881_18 - - - - 0.0000000000000000000000000000006304 129.0
CMS2_k127_192881_19 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000009498 116.0
CMS2_k127_192881_2 AMP-binding enzyme C-terminal domain K00666 - - 6.888e-239 771.0
CMS2_k127_192881_20 Adenylate cyclase - - - 0.00000000000000004337 95.0
CMS2_k127_192881_21 - - - - 0.000000000000002363 83.0
CMS2_k127_192881_23 - - - - 0.0000168 51.0
CMS2_k127_192881_24 - - - - 0.00006071 55.0
CMS2_k127_192881_25 S-layer homology domain - - - 0.0003775 52.0
CMS2_k127_192881_3 Tripartite tricarboxylate transporter TctA family K07793 - - 2.694e-234 742.0
CMS2_k127_192881_4 nitrogen regulation protein K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 8.663e-196 641.0
CMS2_k127_192881_5 CoA-transferase family III K07749 - 2.8.3.16 1.773e-195 619.0
CMS2_k127_192881_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 493.0
CMS2_k127_192881_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 419.0
CMS2_k127_192881_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 406.0
CMS2_k127_192881_9 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 399.0
CMS2_k127_2021898_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.295e-247 798.0
CMS2_k127_2021898_1 BT1 family - - - 8.527e-226 715.0
CMS2_k127_2021898_10 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 461.0
CMS2_k127_2021898_11 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 448.0
CMS2_k127_2021898_12 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 445.0
CMS2_k127_2021898_13 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 432.0
CMS2_k127_2021898_14 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 434.0
CMS2_k127_2021898_15 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 423.0
CMS2_k127_2021898_16 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 428.0
CMS2_k127_2021898_17 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 359.0
CMS2_k127_2021898_18 Lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 359.0
CMS2_k127_2021898_19 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 351.0
CMS2_k127_2021898_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 6.28e-216 700.0
CMS2_k127_2021898_20 Amino-transferase class IV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 343.0
CMS2_k127_2021898_21 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 344.0
CMS2_k127_2021898_22 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 291.0
CMS2_k127_2021898_23 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0035529,GO:0043167,GO:0043169,GO:0046872,GO:0046914 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001172 286.0
CMS2_k127_2021898_24 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000004113 255.0
CMS2_k127_2021898_25 PFAM NnrUfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001848 256.0
CMS2_k127_2021898_26 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000004464 252.0
CMS2_k127_2021898_27 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000494 233.0
CMS2_k127_2021898_28 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000001425 205.0
CMS2_k127_2021898_29 - - - - 0.0000000000000000000000000000000000000000000000001939 197.0
CMS2_k127_2021898_3 COG1960 Acyl-CoA dehydrogenases K14448 - 1.3.8.12 7.794e-196 646.0
CMS2_k127_2021898_30 PIN domain - - - 0.0000000000000000000000000000000005208 139.0
CMS2_k127_2021898_31 - - - - 0.000000000000000000000000004045 114.0
CMS2_k127_2021898_32 - - - - 0.0000000000000002778 88.0
CMS2_k127_2021898_33 - - - - 0.000000000000000428 80.0
CMS2_k127_2021898_34 Putative regulatory protein - - - 0.000000000000006312 87.0
CMS2_k127_2021898_35 - - - - 0.0000001772 63.0
CMS2_k127_2021898_36 PFAM NHL repeat containing protein - - - 0.000003976 60.0
CMS2_k127_2021898_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 577.0
CMS2_k127_2021898_5 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 572.0
CMS2_k127_2021898_6 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 571.0
CMS2_k127_2021898_7 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 486.0
CMS2_k127_2021898_8 Psort location Cytoplasmic, score 7.50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 510.0
CMS2_k127_2021898_9 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 483.0
CMS2_k127_2092911_0 5-oxoprolinase K01469 - 3.5.2.9 0.0 2003.0
CMS2_k127_2092911_1 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 375.0
CMS2_k127_2092911_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 374.0
CMS2_k127_2092911_3 PFAM lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000001816 228.0
CMS2_k127_2092911_4 MazG-like family - - - 0.000000000000000000000000001033 127.0
CMS2_k127_2092911_5 Type II secretion system protein B K02451 - - 0.0000000003012 68.0
CMS2_k127_2101310_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 4.243e-267 830.0
CMS2_k127_2101310_1 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006601 608.0
CMS2_k127_2101310_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 589.0
CMS2_k127_2101310_3 PFAM aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 483.0
CMS2_k127_2101310_4 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 387.0
CMS2_k127_2101310_5 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000001348 175.0
CMS2_k127_2101310_6 - - - - 0.00000000000000000000001339 106.0
CMS2_k127_2101310_7 -O-antigen - - - 0.00000000000000000001637 104.0
CMS2_k127_2101310_8 COGs COG0790 FOG TPR repeat SEL1 subfamily K07126 - - 0.000000000001841 77.0
CMS2_k127_2117705_0 E1-E2 ATPase K17686 - 3.6.3.54 0.0 1150.0
CMS2_k127_2117705_1 Catalyzes the dehydration of galactarate to form 5- dehydro-4-deoxy-D-glucarate K01685 - 4.2.1.7 3.879e-238 752.0
CMS2_k127_2117705_10 alpha/beta hydrolase fold - - - 0.0007487 45.0
CMS2_k127_2117705_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 483.0
CMS2_k127_2117705_3 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 312.0
CMS2_k127_2117705_4 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009228 270.0
CMS2_k127_2117705_5 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000005577 223.0
CMS2_k127_2117705_6 Transcriptional - - - 0.0000000000000000000000000000000000000003509 155.0
CMS2_k127_2117705_7 Cupin 2, conserved barrel domain protein K21700 - - 0.0000000000000000000000006693 111.0
CMS2_k127_2117705_8 Alpha beta hydrolase - - - 0.00000000000003661 83.0
CMS2_k127_2117705_9 Domain of Unknown Function (DUF349) - - - 0.0000006057 59.0
CMS2_k127_216598_0 CoA binding domain - - - 4.199e-235 750.0
CMS2_k127_216598_1 PFAM Dehydrogenase, E1 component K00166 - 1.2.4.4 1.882e-210 661.0
CMS2_k127_216598_10 LysR substrate binding domain K21645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003147 284.0
CMS2_k127_216598_11 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009693 258.0
CMS2_k127_216598_12 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000013 204.0
CMS2_k127_216598_13 AraC-binding-like domain - - - 0.00000000000000000000000000000000000000000000001916 183.0
CMS2_k127_216598_14 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000001276 183.0
CMS2_k127_216598_15 SMART regulatory protein, ArsR K03892 - - 0.0000000000000000000000000000008368 137.0
CMS2_k127_216598_16 PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30 - - - 0.000000000000000000000000000014 127.0
CMS2_k127_216598_17 Cupin domain - - - 0.000000000000000000005768 104.0
CMS2_k127_216598_18 PFAM Phosphoglycerate mutase - - - 0.000000000000000001759 87.0
CMS2_k127_216598_19 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.000000000000000003585 91.0
CMS2_k127_216598_2 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 610.0
CMS2_k127_216598_3 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 559.0
CMS2_k127_216598_4 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 529.0
CMS2_k127_216598_5 PFAM SMP-30 Gluconolaconase LRE domain protein K01053,K14274 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 474.0
CMS2_k127_216598_6 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 431.0
CMS2_k127_216598_7 e3 binding domain K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 440.0
CMS2_k127_216598_8 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 431.0
CMS2_k127_216598_9 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 386.0
CMS2_k127_2166653_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1292.0
CMS2_k127_2166653_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1256.0
CMS2_k127_2166653_10 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005379 284.0
CMS2_k127_2166653_11 phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002247 252.0
CMS2_k127_2166653_12 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000347 248.0
CMS2_k127_2166653_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000399 214.0
CMS2_k127_2166653_14 glycosylase K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000000000001633 196.0
CMS2_k127_2166653_15 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000002077 181.0
CMS2_k127_2166653_16 LysE type translocator - - - 0.0000000000000000000000000000000000000217 151.0
CMS2_k127_2166653_17 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000008836 101.0
CMS2_k127_2166653_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1066.0
CMS2_k127_2166653_3 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 1.935e-305 957.0
CMS2_k127_2166653_4 Molecular chaperone. Has ATPase activity K04079 - - 5.243e-290 905.0
CMS2_k127_2166653_5 Transport of potassium into the cell K03549 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 614.0
CMS2_k127_2166653_6 ABC transporter K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 440.0
CMS2_k127_2166653_7 Predicted permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 301.0
CMS2_k127_2166653_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 293.0
CMS2_k127_2166653_9 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000092 290.0
CMS2_k127_2168516_0 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 - 6.1.1.4 2.424e-227 711.0
CMS2_k127_2168516_1 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007633 286.0
CMS2_k127_2168516_2 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000008988 127.0
CMS2_k127_2182665_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1651.0
CMS2_k127_2182665_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.114e-319 983.0
CMS2_k127_2182665_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 438.0
CMS2_k127_2182665_11 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 438.0
CMS2_k127_2182665_12 4Fe-4S ferredoxin, iron-sulfur binding K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 403.0
CMS2_k127_2182665_13 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 398.0
CMS2_k127_2182665_14 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009557 385.0
CMS2_k127_2182665_15 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 370.0
CMS2_k127_2182665_16 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 384.0
CMS2_k127_2182665_17 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 358.0
CMS2_k127_2182665_18 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 332.0
CMS2_k127_2182665_19 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 346.0
CMS2_k127_2182665_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 6.537e-276 883.0
CMS2_k127_2182665_20 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 331.0
CMS2_k127_2182665_21 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 336.0
CMS2_k127_2182665_22 formate dehydrogenase K00127 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 312.0
CMS2_k127_2182665_23 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 306.0
CMS2_k127_2182665_24 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001207 284.0
CMS2_k127_2182665_25 Acetyltransferase (GNAT) domain K22479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000211 273.0
CMS2_k127_2182665_26 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000002623 245.0
CMS2_k127_2182665_27 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000001542 243.0
CMS2_k127_2182665_28 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000000000000000001103 216.0
CMS2_k127_2182665_29 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000004219 212.0
CMS2_k127_2182665_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 6.076e-206 648.0
CMS2_k127_2182665_30 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000001659 194.0
CMS2_k127_2182665_31 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000003736 180.0
CMS2_k127_2182665_32 Chaperone protein TorD - - - 0.0000000000000000000000000000000000000001021 162.0
CMS2_k127_2182665_33 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000009251 136.0
CMS2_k127_2182665_34 Cytochrome c - - - 0.0000000000000000000000000000000004461 138.0
CMS2_k127_2182665_35 rieske 2fe-2s - - - 0.00000000000000000000000000000007662 130.0
CMS2_k127_2182665_36 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000000004646 119.0
CMS2_k127_2182665_37 cytochrome - - - 0.0000000000000000000000004708 109.0
CMS2_k127_2182665_38 Protein of unknown function (DUF1059) - - - 0.00000000000000000000000481 102.0
CMS2_k127_2182665_39 Protein of unknown function (DUF3305) - - - 0.0000000000000000000001066 105.0
CMS2_k127_2182665_4 VWA containing CoxE family protein K09989 - - 5.851e-205 654.0
CMS2_k127_2182665_40 Protein of unknown function (DUF3306) - - - 0.000000000000000000001307 109.0
CMS2_k127_2182665_41 Domain of unknown function (DUF4845) - - - 0.000000000000000000004608 98.0
CMS2_k127_2182665_42 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000733 100.0
CMS2_k127_2182665_43 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000003099 79.0
CMS2_k127_2182665_44 - - - - 0.0000001336 62.0
CMS2_k127_2182665_45 - - - - 0.0001452 49.0
CMS2_k127_2182665_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 627.0
CMS2_k127_2182665_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 592.0
CMS2_k127_2182665_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 537.0
CMS2_k127_2182665_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 524.0
CMS2_k127_2182665_9 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 506.0
CMS2_k127_2195636_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 2.208e-307 954.0
CMS2_k127_2195636_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.052e-258 830.0
CMS2_k127_2195636_10 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 524.0
CMS2_k127_2195636_11 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 479.0
CMS2_k127_2195636_12 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 473.0
CMS2_k127_2195636_13 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 491.0
CMS2_k127_2195636_14 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 474.0
CMS2_k127_2195636_15 phosphate transport system K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 462.0
CMS2_k127_2195636_16 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 458.0
CMS2_k127_2195636_17 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 469.0
CMS2_k127_2195636_18 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 481.0
CMS2_k127_2195636_19 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 453.0
CMS2_k127_2195636_2 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 3.453e-219 701.0
CMS2_k127_2195636_20 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 435.0
CMS2_k127_2195636_21 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 417.0
CMS2_k127_2195636_22 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 412.0
CMS2_k127_2195636_23 PFAM surface antigen (D15) K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 415.0
CMS2_k127_2195636_24 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 406.0
CMS2_k127_2195636_25 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 386.0
CMS2_k127_2195636_26 ROK family K00845,K00847 - 2.7.1.2,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 369.0
CMS2_k127_2195636_27 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 374.0
CMS2_k127_2195636_28 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 357.0
CMS2_k127_2195636_29 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 387.0
CMS2_k127_2195636_3 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 2.049e-195 621.0
CMS2_k127_2195636_30 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 353.0
CMS2_k127_2195636_31 Peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 351.0
CMS2_k127_2195636_32 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 330.0
CMS2_k127_2195636_33 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 325.0
CMS2_k127_2195636_34 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 316.0
CMS2_k127_2195636_35 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 312.0
CMS2_k127_2195636_36 Pfam SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 335.0
CMS2_k127_2195636_37 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 312.0
CMS2_k127_2195636_38 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 318.0
CMS2_k127_2195636_39 Major facilitator superfamily K07552,K18552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 304.0
CMS2_k127_2195636_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 2.838e-195 614.0
CMS2_k127_2195636_40 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002985 279.0
CMS2_k127_2195636_41 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001167 282.0
CMS2_k127_2195636_42 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000539 264.0
CMS2_k127_2195636_43 Putative heavy-metal chelation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000989 269.0
CMS2_k127_2195636_44 Conserved Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001389 265.0
CMS2_k127_2195636_45 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004276 271.0
CMS2_k127_2195636_46 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005418 263.0
CMS2_k127_2195636_47 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007806 252.0
CMS2_k127_2195636_48 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000007373 252.0
CMS2_k127_2195636_49 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000007821 250.0
CMS2_k127_2195636_5 Mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 566.0
CMS2_k127_2195636_50 Transcriptional regulator, Crp Fnr family K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000001117 237.0
CMS2_k127_2195636_51 Nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000000000000000000000000000001852 229.0
CMS2_k127_2195636_52 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000000002932 221.0
CMS2_k127_2195636_53 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000003818 218.0
CMS2_k127_2195636_54 Belongs to the DnaA family K10763 - - 0.00000000000000000000000000000000000000000000000000003103 209.0
CMS2_k127_2195636_55 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000003958 186.0
CMS2_k127_2195636_56 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000005258 193.0
CMS2_k127_2195636_57 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000006923 202.0
CMS2_k127_2195636_58 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000009625 183.0
CMS2_k127_2195636_59 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000002791 182.0
CMS2_k127_2195636_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 587.0
CMS2_k127_2195636_60 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000133 183.0
CMS2_k127_2195636_61 Shikimate kinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000007612 179.0
CMS2_k127_2195636_62 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000007668 174.0
CMS2_k127_2195636_63 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000002362 161.0
CMS2_k127_2195636_64 lipid carrier protein - - - 0.0000000000000000000000000000000000000000166 172.0
CMS2_k127_2195636_65 Ribosomal protein S21 K02970 - - 0.00000000000000000000000000000001968 129.0
CMS2_k127_2195636_66 Cytochrome c K08738 - - 0.00000000000000000000000000003097 120.0
CMS2_k127_2195636_67 AAA domain - - - 0.000000000000000000000000002532 126.0
CMS2_k127_2195636_68 Protein of unknown function (DUF2788) - - - 0.000000000000000000000000192 106.0
CMS2_k127_2195636_69 Invasion gene expression up-regulator SirB - - - 0.000000000000000000000002156 107.0
CMS2_k127_2195636_7 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 518.0
CMS2_k127_2195636_70 conserved protein (DUF2249) - - - 0.0000000000269 74.0
CMS2_k127_2195636_71 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000006536 71.0
CMS2_k127_2195636_72 PFAM cytochrome - - - 0.00000008232 65.0
CMS2_k127_2195636_73 Plasmid stability protein K21495 - - 0.000001063 55.0
CMS2_k127_2195636_8 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 526.0
CMS2_k127_2195636_9 Peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 513.0
CMS2_k127_2240486_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 6.657e-246 771.0
CMS2_k127_2240486_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 9.128e-241 764.0
CMS2_k127_2240486_10 LysM domain K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 514.0
CMS2_k127_2240486_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 438.0
CMS2_k127_2240486_12 extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 425.0
CMS2_k127_2240486_13 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 415.0
CMS2_k127_2240486_14 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 367.0
CMS2_k127_2240486_15 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 325.0
CMS2_k127_2240486_16 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 326.0
CMS2_k127_2240486_17 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 297.0
CMS2_k127_2240486_18 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000001011 246.0
CMS2_k127_2240486_19 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000000000003492 211.0
CMS2_k127_2240486_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.184e-220 707.0
CMS2_k127_2240486_20 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000009399 209.0
CMS2_k127_2240486_21 binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000008924 177.0
CMS2_k127_2240486_22 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000003913 164.0
CMS2_k127_2240486_23 Sporulation related domain K03749 - - 0.000000000000000000000000000004735 128.0
CMS2_k127_2240486_24 toxin biosynthetic process K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.0000000000000000007575 99.0
CMS2_k127_2240486_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.163e-206 652.0
CMS2_k127_2240486_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 580.0
CMS2_k127_2240486_5 COG1960 Acyl-CoA dehydrogenases K19966 - 3.13.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009793 610.0
CMS2_k127_2240486_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 560.0
CMS2_k127_2240486_7 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 561.0
CMS2_k127_2240486_8 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 553.0
CMS2_k127_2240486_9 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 507.0
CMS2_k127_2286451_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 6.778e-266 838.0
CMS2_k127_2286451_1 COG1180 Pyruvate-formate lyase-activating enzyme K20449 - 1.3.7.1 1.416e-210 700.0
CMS2_k127_2286451_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K09740 - - 0.0000000000000000000000000000000000000000000000000000001432 220.0
CMS2_k127_2289507_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.351e-297 919.0
CMS2_k127_2289507_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.259e-280 872.0
CMS2_k127_2289507_10 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 507.0
CMS2_k127_2289507_11 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 481.0
CMS2_k127_2289507_12 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 447.0
CMS2_k127_2289507_13 Mannitol dehydrogenase Rossmann domain K00040 - 1.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 459.0
CMS2_k127_2289507_14 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 422.0
CMS2_k127_2289507_15 Malate/L-lactate dehydrogenase K00016,K00073 - 1.1.1.27,1.1.1.350 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 409.0
CMS2_k127_2289507_16 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 429.0
CMS2_k127_2289507_17 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 388.0
CMS2_k127_2289507_18 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 403.0
CMS2_k127_2289507_19 TOBE domain K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 355.0
CMS2_k127_2289507_2 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 4.295e-219 691.0
CMS2_k127_2289507_20 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 321.0
CMS2_k127_2289507_21 Enoyl-(Acyl carrier protein) reductase K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 314.0
CMS2_k127_2289507_22 PFAM Short-chain dehydrogenase reductase SDR K18335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 311.0
CMS2_k127_2289507_23 COG1177 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 310.0
CMS2_k127_2289507_24 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00050 - 1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 308.0
CMS2_k127_2289507_25 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 297.0
CMS2_k127_2289507_26 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001299 265.0
CMS2_k127_2289507_27 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004871 241.0
CMS2_k127_2289507_28 FCD K22293 - - 0.00000000000000000000000000000000000000000000000000000000001513 217.0
CMS2_k127_2289507_29 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000002216 179.0
CMS2_k127_2289507_3 ABC transporter transmembrane region K06147 - - 3.773e-209 693.0
CMS2_k127_2289507_30 Tripartite ATP-independent periplasmic transporter - - - 0.0000000000000000000000000000000000000000000000003889 189.0
CMS2_k127_2289507_31 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000002732 153.0
CMS2_k127_2289507_32 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000001933 148.0
CMS2_k127_2289507_33 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000005707 149.0
CMS2_k127_2289507_34 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000002736 139.0
CMS2_k127_2289507_35 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000071 106.0
CMS2_k127_2289507_36 CNP1-like family - - - 0.000000000000000000005938 102.0
CMS2_k127_2289507_37 Heavy-metal resistance - - - 0.0000000000003599 79.0
CMS2_k127_2289507_39 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000001644 67.0
CMS2_k127_2289507_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 9.063e-194 614.0
CMS2_k127_2289507_5 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 584.0
CMS2_k127_2289507_6 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 595.0
CMS2_k127_2289507_7 COG1840 ABC-type Fe3 transport system, periplasmic component K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 548.0
CMS2_k127_2289507_8 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 541.0
CMS2_k127_2289507_9 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 519.0
CMS2_k127_240335_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 4.738e-207 650.0
CMS2_k127_240335_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.647e-206 665.0
CMS2_k127_240335_10 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000002839 201.0
CMS2_k127_240335_11 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000000000000005945 151.0
CMS2_k127_240335_12 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000002194 119.0
CMS2_k127_240335_13 positive regulation of growth - - - 0.0000000000000000007824 88.0
CMS2_k127_240335_14 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000805 80.0
CMS2_k127_240335_2 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 3.99e-205 646.0
CMS2_k127_240335_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 502.0
CMS2_k127_240335_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 456.0
CMS2_k127_240335_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 314.0
CMS2_k127_240335_6 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006388 300.0
CMS2_k127_240335_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006158 290.0
CMS2_k127_240335_8 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000676 255.0
CMS2_k127_240335_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000004679 243.0
CMS2_k127_2447579_0 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000398 279.0
CMS2_k127_2447579_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000006828 165.0
CMS2_k127_2447579_2 Protein of unknown function (DUF2933) - - - 0.000000000000008007 85.0
CMS2_k127_2447579_3 Methyltransferase - - - 0.0000009448 51.0
CMS2_k127_2447579_4 - - - - 0.0001233 46.0
CMS2_k127_2447579_5 FtsX-like permease family K02004 - - 0.0008306 51.0
CMS2_k127_2501283_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 590.0
CMS2_k127_2501283_1 TIGRFAM amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 532.0
CMS2_k127_2501283_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 328.0
CMS2_k127_2501283_11 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003679 293.0
CMS2_k127_2501283_12 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000000000000000000000000000005643 166.0
CMS2_k127_2501283_13 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000004866 105.0
CMS2_k127_2501283_14 oxidation-reduction process - - - 0.00001654 53.0
CMS2_k127_2501283_2 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 436.0
CMS2_k127_2501283_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 451.0
CMS2_k127_2501283_4 nadph quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008797 424.0
CMS2_k127_2501283_5 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 415.0
CMS2_k127_2501283_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 376.0
CMS2_k127_2501283_7 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 359.0
CMS2_k127_2501283_8 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 370.0
CMS2_k127_2501283_9 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 353.0
CMS2_k127_2601139_0 signal transduction histidine kinase K07678 - 2.7.13.3 1.459e-201 689.0
CMS2_k127_2601139_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 394.0
CMS2_k127_2601139_2 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000000002141 196.0
CMS2_k127_2601139_3 SMART cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000007136 201.0
CMS2_k127_2601139_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000001093 190.0
CMS2_k127_2601139_5 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000009561 153.0
CMS2_k127_2601139_6 - - - - 0.0000000000000000000000004058 108.0
CMS2_k127_2601139_7 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000002963 102.0
CMS2_k127_2601139_8 - - - - 0.0000000000000001605 91.0
CMS2_k127_2601139_9 Transcriptional regulator C-terminal region - - - 0.0000000000002194 72.0
CMS2_k127_2644784_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 4.392e-230 732.0
CMS2_k127_2644784_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 9.684e-221 690.0
CMS2_k127_2644784_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009391 368.0
CMS2_k127_2644784_11 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 366.0
CMS2_k127_2644784_12 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 336.0
CMS2_k127_2644784_13 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 314.0
CMS2_k127_2644784_14 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 295.0
CMS2_k127_2644784_15 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000448 258.0
CMS2_k127_2644784_16 riboflavin synthase alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000008168 273.0
CMS2_k127_2644784_17 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002246 247.0
CMS2_k127_2644784_18 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008611 246.0
CMS2_k127_2644784_19 regulator of disulfide bond formation K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000003636 228.0
CMS2_k127_2644784_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 8.148e-203 638.0
CMS2_k127_2644784_20 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000002947 223.0
CMS2_k127_2644784_21 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000002657 213.0
CMS2_k127_2644784_22 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000002861 210.0
CMS2_k127_2644784_23 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000281 219.0
CMS2_k127_2644784_24 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000000009703 204.0
CMS2_k127_2644784_25 Phosphoglycerate mutase K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000001895 209.0
CMS2_k127_2644784_26 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000005207 192.0
CMS2_k127_2644784_27 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000925 188.0
CMS2_k127_2644784_28 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000003972 184.0
CMS2_k127_2644784_29 - - - - 0.00000000000000000000000000000000000000000007529 169.0
CMS2_k127_2644784_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.026e-194 625.0
CMS2_k127_2644784_30 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000757 164.0
CMS2_k127_2644784_31 MarR family - - - 0.000000000000000000000000000000000000001498 153.0
CMS2_k127_2644784_32 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000003119 157.0
CMS2_k127_2644784_33 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000000003205 148.0
CMS2_k127_2644784_34 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000003617 132.0
CMS2_k127_2644784_35 Protein of unknown function (DUF541) - - - 0.000000000000000000000000000007521 128.0
CMS2_k127_2644784_36 Modulates RecA activity K03565 - - 0.00000000000000000000000002116 121.0
CMS2_k127_2644784_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 577.0
CMS2_k127_2644784_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 523.0
CMS2_k127_2644784_6 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 499.0
CMS2_k127_2644784_7 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 510.0
CMS2_k127_2644784_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 487.0
CMS2_k127_2644784_9 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 377.0
CMS2_k127_2645155_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 480.0
CMS2_k127_2645155_1 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 425.0
CMS2_k127_2645155_10 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004144 280.0
CMS2_k127_2645155_11 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001585 259.0
CMS2_k127_2645155_12 - - - - 0.0000000000000000000000000000000000000000000000000000000002393 207.0
CMS2_k127_2645155_13 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000000000000000000000000000001129 203.0
CMS2_k127_2645155_14 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000000003986 179.0
CMS2_k127_2645155_15 DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000006695 173.0
CMS2_k127_2645155_16 Chalcone isomerase-like - - - 0.000000000000000000000000000000008603 138.0
CMS2_k127_2645155_17 LTXXQ motif family protein - - - 0.0000000000000000001092 100.0
CMS2_k127_2645155_18 HPP family K07168 - - 0.00000000000000002421 96.0
CMS2_k127_2645155_19 Universal stress protein family - - - 0.00000000000000008157 86.0
CMS2_k127_2645155_2 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 442.0
CMS2_k127_2645155_3 Histidine kinase K05962 - 2.7.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 435.0
CMS2_k127_2645155_4 protocatechuate 3,4-dioxygenase beta subunit K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 399.0
CMS2_k127_2645155_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 339.0
CMS2_k127_2645155_6 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 331.0
CMS2_k127_2645155_7 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 304.0
CMS2_k127_2645155_8 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003248 283.0
CMS2_k127_2645155_9 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002366 261.0
CMS2_k127_2660610_0 Tripartite tricarboxylate transporter TctA family - - - 6.361e-210 662.0
CMS2_k127_2660610_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 414.0
CMS2_k127_2660610_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 308.0
CMS2_k127_2660610_3 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000364 187.0
CMS2_k127_2660610_4 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000002333 180.0
CMS2_k127_2660610_5 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000007643 130.0
CMS2_k127_2660610_6 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.00000000000002403 75.0
CMS2_k127_2692384_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.582e-300 946.0
CMS2_k127_2692384_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 2.002e-216 678.0
CMS2_k127_2692384_10 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001664 261.0
CMS2_k127_2692384_11 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005573 280.0
CMS2_k127_2692384_12 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000007177 235.0
CMS2_k127_2692384_13 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000345 180.0
CMS2_k127_2692384_14 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000002596 171.0
CMS2_k127_2692384_15 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000002229 158.0
CMS2_k127_2692384_16 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000001052 94.0
CMS2_k127_2692384_17 - - - - 0.0000000000448 76.0
CMS2_k127_2692384_2 Putative diguanylate phosphodiesterase K13243 - 3.1.4.52 3.39e-216 705.0
CMS2_k127_2692384_3 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 572.0
CMS2_k127_2692384_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 395.0
CMS2_k127_2692384_5 NlpB/DapX lipoprotein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 383.0
CMS2_k127_2692384_6 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 362.0
CMS2_k127_2692384_7 PFAM Cupin 4 family protein K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 366.0
CMS2_k127_2692384_8 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 340.0
CMS2_k127_2692384_9 SMART phosphoesterase PHP domain protein K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 352.0
CMS2_k127_2745797_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 2.615e-260 811.0
CMS2_k127_2745797_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.555e-232 729.0
CMS2_k127_2745797_10 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 379.0
CMS2_k127_2745797_11 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 353.0
CMS2_k127_2745797_12 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 348.0
CMS2_k127_2745797_13 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 346.0
CMS2_k127_2745797_14 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 328.0
CMS2_k127_2745797_15 Squalene epoxidase K03184,K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 333.0
CMS2_k127_2745797_16 GGDEF domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002588 296.0
CMS2_k127_2745797_17 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002736 284.0
CMS2_k127_2745797_18 PFAM MltA domain protein K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007507 293.0
CMS2_k127_2745797_19 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000028 229.0
CMS2_k127_2745797_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 8.992e-211 670.0
CMS2_k127_2745797_20 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000005477 228.0
CMS2_k127_2745797_21 Platelet-activating factor acetylhydrolase plasma intracellular isoform II - - - 0.0000000000000000000000000000000000000000000000000000000009889 229.0
CMS2_k127_2745797_22 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000007422 207.0
CMS2_k127_2745797_23 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000002945 191.0
CMS2_k127_2745797_24 PFAM ApaG domain protein K06195 - - 0.0000000000000000000000000000000000000000000000000003658 187.0
CMS2_k127_2745797_25 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000001343 186.0
CMS2_k127_2745797_26 phenylacetic acid degradation protein K02614 - - 0.0000000000000000000000000000000000000000000003654 171.0
CMS2_k127_2745797_27 - - - - 0.000000000000000000000000000000002315 129.0
CMS2_k127_2745797_28 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.00000000000000001646 89.0
CMS2_k127_2745797_3 protease with the C-terminal PDZ domain - - - 6.343e-206 684.0
CMS2_k127_2745797_30 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000001659 64.0
CMS2_k127_2745797_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 544.0
CMS2_k127_2745797_5 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 473.0
CMS2_k127_2745797_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 457.0
CMS2_k127_2745797_7 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 439.0
CMS2_k127_2745797_8 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 415.0
CMS2_k127_2745797_9 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 373.0
CMS2_k127_2774107_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 2.033e-244 772.0
CMS2_k127_2774107_1 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 6.659e-226 703.0
CMS2_k127_2774107_10 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 396.0
CMS2_k127_2774107_11 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 393.0
CMS2_k127_2774107_12 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 381.0
CMS2_k127_2774107_13 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 345.0
CMS2_k127_2774107_14 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 342.0
CMS2_k127_2774107_15 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 326.0
CMS2_k127_2774107_16 ChrR Cupin-like domain K05913 - 1.13.11.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 298.0
CMS2_k127_2774107_17 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 289.0
CMS2_k127_2774107_18 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 288.0
CMS2_k127_2774107_19 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000003219 246.0
CMS2_k127_2774107_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 3.72e-224 704.0
CMS2_k127_2774107_20 rod shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000000000000000000000000000000000006381 226.0
CMS2_k127_2774107_21 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000002937 201.0
CMS2_k127_2774107_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000009923 200.0
CMS2_k127_2774107_23 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000001767 186.0
CMS2_k127_2774107_24 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000002434 170.0
CMS2_k127_2774107_25 transcriptional - - - 0.00000000000000000000000000000000000000003788 157.0
CMS2_k127_2774107_26 GYD domain - - - 0.00000000000000000000000000000000131 133.0
CMS2_k127_2774107_27 RNA-binding protein - - - 0.00000000000000000000000000001714 125.0
CMS2_k127_2774107_28 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000001067 128.0
CMS2_k127_2774107_29 Rubredoxin - - - 0.000000000000000000000001486 104.0
CMS2_k127_2774107_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.007e-206 659.0
CMS2_k127_2774107_31 TRANSCRIPTIONal - - - 0.00001035 55.0
CMS2_k127_2774107_32 ubiE/COQ5 methyltransferase family - - - 0.00001591 47.0
CMS2_k127_2774107_4 Cell shape determining protein, MreB Mrl family K03569 - - 6.295e-204 639.0
CMS2_k127_2774107_5 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 613.0
CMS2_k127_2774107_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 489.0
CMS2_k127_2774107_7 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 453.0
CMS2_k127_2774107_8 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 411.0
CMS2_k127_2774107_9 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 394.0
CMS2_k127_2791944_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.0 1021.0
CMS2_k127_2791944_1 belongs to the aldehyde dehydrogenase family K00137 - 1.2.1.19 2.553e-242 756.0
CMS2_k127_2791944_10 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000009794 220.0
CMS2_k127_2791944_11 Asparaginase, N-terminal K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000004294 204.0
CMS2_k127_2791944_12 2-keto-4-pentenoate hydratase K01617 - 4.1.1.77 0.000000000000000000000000000000000000000000000000001549 201.0
CMS2_k127_2791944_2 Bacterial extracellular solute-binding protein K02055 - - 5.237e-203 638.0
CMS2_k127_2791944_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 569.0
CMS2_k127_2791944_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 437.0
CMS2_k127_2791944_5 ABC transporter (Permease K02054 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 422.0
CMS2_k127_2791944_6 ABC transporter permease K02053 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 406.0
CMS2_k127_2791944_7 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 332.0
CMS2_k127_2791944_8 Ammonia monooxygenase K07120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 301.0
CMS2_k127_2791944_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001611 249.0
CMS2_k127_2815687_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1539.0
CMS2_k127_2815687_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.0 1175.0
CMS2_k127_2815687_10 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 563.0
CMS2_k127_2815687_11 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 540.0
CMS2_k127_2815687_12 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 519.0
CMS2_k127_2815687_13 PFAM AFG1-family ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 479.0
CMS2_k127_2815687_14 Phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 474.0
CMS2_k127_2815687_15 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 443.0
CMS2_k127_2815687_16 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008884 398.0
CMS2_k127_2815687_17 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 384.0
CMS2_k127_2815687_18 isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 356.0
CMS2_k127_2815687_19 GntR family K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 339.0
CMS2_k127_2815687_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1012.0
CMS2_k127_2815687_20 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 318.0
CMS2_k127_2815687_21 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 315.0
CMS2_k127_2815687_22 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006388 277.0
CMS2_k127_2815687_23 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000398 265.0
CMS2_k127_2815687_24 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007323 269.0
CMS2_k127_2815687_25 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001381 269.0
CMS2_k127_2815687_26 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000001734 238.0
CMS2_k127_2815687_27 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000006033 224.0
CMS2_k127_2815687_28 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.0000000000000000000000000000000000000000000000000000000000003776 218.0
CMS2_k127_2815687_29 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000003472 214.0
CMS2_k127_2815687_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.443e-229 716.0
CMS2_k127_2815687_30 MerR, DNA binding K19591,K19592 - - 0.0000000000000000000000000000000000000000000000000000000004777 207.0
CMS2_k127_2815687_31 - - - - 0.00000000000000000000000000000000000000000007908 166.0
CMS2_k127_2815687_32 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000000000000000000000000000004203 162.0
CMS2_k127_2815687_33 Succinate dehydrogenase hydrophobic membrane anchor protein K00242 - - 0.000000000000000000000000000000000002963 140.0
CMS2_k127_2815687_34 - - - - 0.00000000000000000000000008034 111.0
CMS2_k127_2815687_35 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000001288 94.0
CMS2_k127_2815687_36 Heavy-metal-associated domain K07213 - - 0.0000000000000000001501 93.0
CMS2_k127_2815687_37 YHS domain - - - 0.000000000000000007957 85.0
CMS2_k127_2815687_38 Protein of unknown function (DUF465) - - - 0.000000000000007811 79.0
CMS2_k127_2815687_39 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.00000000000004256 73.0
CMS2_k127_2815687_4 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 9.796e-224 704.0
CMS2_k127_2815687_40 - - - - 0.0000000000001456 75.0
CMS2_k127_2815687_41 Protein of unknown function (DUF2933) - - - 0.0000000000001791 78.0
CMS2_k127_2815687_5 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 1.068e-216 679.0
CMS2_k127_2815687_6 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 3.939e-213 679.0
CMS2_k127_2815687_7 Belongs to the citrate synthase family K01659 - 2.3.3.5 1.893e-205 644.0
CMS2_k127_2815687_8 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 5.183e-197 627.0
CMS2_k127_2815687_9 helicase K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 616.0
CMS2_k127_2826016_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1257.0
CMS2_k127_2826016_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1228.0
CMS2_k127_2826016_10 ABC-type branched-chain amino acid transport system, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 549.0
CMS2_k127_2826016_11 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 579.0
CMS2_k127_2826016_12 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 539.0
CMS2_k127_2826016_13 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 529.0
CMS2_k127_2826016_14 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 523.0
CMS2_k127_2826016_15 PFAM ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 525.0
CMS2_k127_2826016_16 PFAM aminotransferase, class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 499.0
CMS2_k127_2826016_17 Type II/IV secretion system protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 475.0
CMS2_k127_2826016_18 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 455.0
CMS2_k127_2826016_19 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 459.0
CMS2_k127_2826016_2 Required for chromosome condensation and partitioning K03529 - - 0.0 1106.0
CMS2_k127_2826016_20 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 441.0
CMS2_k127_2826016_21 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 447.0
CMS2_k127_2826016_22 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 421.0
CMS2_k127_2826016_23 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 431.0
CMS2_k127_2826016_24 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 398.0
CMS2_k127_2826016_25 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 391.0
CMS2_k127_2826016_26 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 381.0
CMS2_k127_2826016_27 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 377.0
CMS2_k127_2826016_28 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 396.0
CMS2_k127_2826016_29 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 378.0
CMS2_k127_2826016_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.013e-318 996.0
CMS2_k127_2826016_30 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 380.0
CMS2_k127_2826016_31 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 366.0
CMS2_k127_2826016_32 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 357.0
CMS2_k127_2826016_33 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 349.0
CMS2_k127_2826016_34 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 362.0
CMS2_k127_2826016_35 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 333.0
CMS2_k127_2826016_36 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 304.0
CMS2_k127_2826016_37 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 316.0
CMS2_k127_2826016_38 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004747 274.0
CMS2_k127_2826016_39 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000004258 294.0
CMS2_k127_2826016_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.798e-304 950.0
CMS2_k127_2826016_40 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008162 261.0
CMS2_k127_2826016_41 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000002113 246.0
CMS2_k127_2826016_42 squalene-associated FAD-dependent desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002725 261.0
CMS2_k127_2826016_43 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000006333 237.0
CMS2_k127_2826016_44 squalene synthase HpnC - - - 0.0000000000000000000000000000000000000000000000000000000000000001576 232.0
CMS2_k127_2826016_45 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000002216 229.0
CMS2_k127_2826016_46 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000001385 214.0
CMS2_k127_2826016_47 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000001409 215.0
CMS2_k127_2826016_48 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000004924 209.0
CMS2_k127_2826016_49 Belongs to the skp family K06142 - - 0.00000000000000000000000000000000000000000000000000001912 195.0
CMS2_k127_2826016_5 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.223e-240 784.0
CMS2_k127_2826016_50 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000000001208 162.0
CMS2_k127_2826016_51 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000000003057 156.0
CMS2_k127_2826016_52 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000003158 177.0
CMS2_k127_2826016_53 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000000000837 158.0
CMS2_k127_2826016_54 Peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000001694 122.0
CMS2_k127_2826016_55 Belongs to the ArsC family - - - 0.000000000000000000000000007269 128.0
CMS2_k127_2826016_56 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000006598 106.0
CMS2_k127_2826016_57 - - - - 0.000000000000949 75.0
CMS2_k127_2826016_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.249e-229 721.0
CMS2_k127_2826016_7 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.413e-220 689.0
CMS2_k127_2826016_8 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.483e-207 672.0
CMS2_k127_2826016_9 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 592.0
CMS2_k127_2992671_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1306.0
CMS2_k127_2992671_1 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 1.572e-303 942.0
CMS2_k127_2992671_10 SMART AAA ATPase K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 432.0
CMS2_k127_2992671_11 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 373.0
CMS2_k127_2992671_12 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 369.0
CMS2_k127_2992671_13 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 394.0
CMS2_k127_2992671_14 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 338.0
CMS2_k127_2992671_15 Peptidase M23 K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000001402 255.0
CMS2_k127_2992671_16 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000002237 243.0
CMS2_k127_2992671_17 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000002243 246.0
CMS2_k127_2992671_18 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000001855 177.0
CMS2_k127_2992671_19 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000007265 130.0
CMS2_k127_2992671_2 type II secretion system protein E K02454,K02504,K02652 - - 1.72e-258 809.0
CMS2_k127_2992671_20 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000001588 81.0
CMS2_k127_2992671_21 Protein of unknown function (DUF721) - - - 0.000005224 55.0
CMS2_k127_2992671_3 Extracellular ligand-binding receptor K01999 - - 1.245e-197 625.0
CMS2_k127_2992671_4 Type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 609.0
CMS2_k127_2992671_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 549.0
CMS2_k127_2992671_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 487.0
CMS2_k127_2992671_7 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 484.0
CMS2_k127_2992671_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 437.0
CMS2_k127_2992671_9 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 432.0
CMS2_k127_3052206_0 Ftsk_gamma K03466 - - 1.911e-310 970.0
CMS2_k127_3052206_1 argininosuccinate lyase K01755 - 4.3.2.1 3.392e-228 716.0
CMS2_k127_3052206_10 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 453.0
CMS2_k127_3052206_11 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 451.0
CMS2_k127_3052206_12 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 430.0
CMS2_k127_3052206_13 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 434.0
CMS2_k127_3052206_14 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 370.0
CMS2_k127_3052206_15 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 356.0
CMS2_k127_3052206_16 Transcriptional regulator K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 343.0
CMS2_k127_3052206_17 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 302.0
CMS2_k127_3052206_18 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001094 260.0
CMS2_k127_3052206_19 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000003943 258.0
CMS2_k127_3052206_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 4.424e-211 666.0
CMS2_k127_3052206_20 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000043 248.0
CMS2_k127_3052206_21 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006748 240.0
CMS2_k127_3052206_22 Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001014 230.0
CMS2_k127_3052206_23 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000008276 210.0
CMS2_k127_3052206_24 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000002588 195.0
CMS2_k127_3052206_25 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000006333 207.0
CMS2_k127_3052206_27 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000607 111.0
CMS2_k127_3052206_28 Uroporphyrinogen-III synthase HemD K01719,K13543 - 2.1.1.107,4.2.1.75 0.0000000000000001757 89.0
CMS2_k127_3052206_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.861e-203 646.0
CMS2_k127_3052206_4 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 613.0
CMS2_k127_3052206_5 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 563.0
CMS2_k127_3052206_6 PFAM cyclase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 533.0
CMS2_k127_3052206_7 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 512.0
CMS2_k127_3052206_8 HI0933 family K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 476.0
CMS2_k127_3052206_9 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 454.0
CMS2_k127_3147822_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 6.559e-317 980.0
CMS2_k127_3147822_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.53e-286 882.0
CMS2_k127_3147822_10 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009256 347.0
CMS2_k127_3147822_11 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 340.0
CMS2_k127_3147822_12 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007345 290.0
CMS2_k127_3147822_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000000000001841 212.0
CMS2_k127_3147822_14 - - - - 0.00000000000000000000000000000000000000000000000000000002196 207.0
CMS2_k127_3147822_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000000000000000000000000000000000000000009625 198.0
CMS2_k127_3147822_16 Bacterial transcriptional regulator K20539 - - 0.000000000000000000000000000000000000000000000000000003259 200.0
CMS2_k127_3147822_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000001506 184.0
CMS2_k127_3147822_18 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000002298 189.0
CMS2_k127_3147822_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000001301 136.0
CMS2_k127_3147822_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.265e-281 872.0
CMS2_k127_3147822_20 - - - - 0.000000000000000000000000237 113.0
CMS2_k127_3147822_21 Sel1-like repeats. K07126 - - 0.00000000000000000006373 99.0
CMS2_k127_3147822_22 ATP synthase I chain K02116 - - 0.000000000002059 73.0
CMS2_k127_3147822_3 (GMC) oxidoreductase K00108 - 1.1.99.1 8.291e-238 745.0
CMS2_k127_3147822_4 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 7.097e-232 728.0
CMS2_k127_3147822_5 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.445e-212 696.0
CMS2_k127_3147822_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 424.0
CMS2_k127_3147822_7 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 407.0
CMS2_k127_3147822_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 400.0
CMS2_k127_3147822_9 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 347.0
CMS2_k127_3167888_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 1.216e-216 717.0
CMS2_k127_3167888_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 1.193e-215 689.0
CMS2_k127_3167888_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 556.0
CMS2_k127_3167888_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002268 294.0
CMS2_k127_3167888_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000003863 190.0
CMS2_k127_3167888_5 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000636 94.0
CMS2_k127_3186433_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1049.0
CMS2_k127_3186433_1 ABC transporter transmembrane region K06147 - - 1.584e-250 786.0
CMS2_k127_3186433_10 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 520.0
CMS2_k127_3186433_11 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 519.0
CMS2_k127_3186433_12 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 492.0
CMS2_k127_3186433_13 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 465.0
CMS2_k127_3186433_14 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 445.0
CMS2_k127_3186433_15 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 444.0
CMS2_k127_3186433_16 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 417.0
CMS2_k127_3186433_17 KR domain K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009333 385.0
CMS2_k127_3186433_18 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 376.0
CMS2_k127_3186433_19 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 373.0
CMS2_k127_3186433_2 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 2.226e-222 711.0
CMS2_k127_3186433_20 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 360.0
CMS2_k127_3186433_21 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 394.0
CMS2_k127_3186433_22 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 346.0
CMS2_k127_3186433_23 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 306.0
CMS2_k127_3186433_24 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000108 278.0
CMS2_k127_3186433_25 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000001193 248.0
CMS2_k127_3186433_26 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000000000000000000003084 223.0
CMS2_k127_3186433_27 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000004525 237.0
CMS2_k127_3186433_28 COG2755 Lysophospholipase L1 and related esterases - - - 0.00000000000000000000000000000000000000000000000000000003675 207.0
CMS2_k127_3186433_29 Thioesterase superfamily protein K10806 - - 0.0000000000000000000000000000000000000000000001047 176.0
CMS2_k127_3186433_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 3.001e-213 675.0
CMS2_k127_3186433_30 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000015 182.0
CMS2_k127_3186433_31 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000004601 171.0
CMS2_k127_3186433_32 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000006843 126.0
CMS2_k127_3186433_33 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000002125 79.0
CMS2_k127_3186433_34 - - - - 0.0000001625 56.0
CMS2_k127_3186433_4 acyl-CoA dehydrogenase - - - 9.745e-212 664.0
CMS2_k127_3186433_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 6.677e-211 682.0
CMS2_k127_3186433_6 Belongs to the thiolase family K00632 - 2.3.1.16 2.754e-199 629.0
CMS2_k127_3186433_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008848 630.0
CMS2_k127_3186433_8 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 588.0
CMS2_k127_3186433_9 hydroxypyruvate reductase K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 539.0
CMS2_k127_3194126_0 methionine synthase K00548 - 2.1.1.13 0.0 1820.0
CMS2_k127_3194126_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 295.0
CMS2_k127_3255856_0 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 413.0
CMS2_k127_3255856_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001525 258.0
CMS2_k127_3276409_0 transport system, fused permease components - - - 3.448e-275 865.0
CMS2_k127_3276409_1 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 7.471e-257 805.0
CMS2_k127_3276409_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 614.0
CMS2_k127_3276409_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 545.0
CMS2_k127_3276409_4 transport system periplasmic component K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 424.0
CMS2_k127_3276409_5 fad dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 388.0
CMS2_k127_3276409_6 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 325.0
CMS2_k127_3276409_7 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006292 291.0
CMS2_k127_3276409_8 histidine utilization repressor K05836 - - 0.0000000002913 61.0
CMS2_k127_3276409_9 Domain of unknown function (DUF1850) - - - 0.0001757 54.0
CMS2_k127_3287939_0 transport system, fused permease components - - - 0.0 1051.0
CMS2_k127_3287939_1 extracellular solute-binding protein, family 5 K02035 - - 1.457e-277 860.0
CMS2_k127_3287939_10 LysR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 402.0
CMS2_k127_3287939_11 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 336.0
CMS2_k127_3287939_12 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001778 277.0
CMS2_k127_3287939_13 Tripartite ATP-independent periplasmic transporter dctq component K21394 - - 0.00000000000000000000000000000000000000000000000000001085 196.0
CMS2_k127_3287939_14 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000001586 173.0
CMS2_k127_3287939_15 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000001555 165.0
CMS2_k127_3287939_16 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000121 133.0
CMS2_k127_3287939_17 GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.0000000000000000006135 101.0
CMS2_k127_3287939_18 Protein of unknown function (DUF1810) - - - 0.000000000000003072 87.0
CMS2_k127_3287939_19 - - - - 0.000000003258 63.0
CMS2_k127_3287939_2 TRAP C4-dicarboxylate transport system permease DctM subunit K11690,K21393 - - 2.094e-194 623.0
CMS2_k127_3287939_20 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0005251 48.0
CMS2_k127_3287939_3 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 627.0
CMS2_k127_3287939_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 556.0
CMS2_k127_3287939_5 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 514.0
CMS2_k127_3287939_6 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 507.0
CMS2_k127_3287939_7 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 494.0
CMS2_k127_3287939_8 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 436.0
CMS2_k127_3287939_9 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 394.0
CMS2_k127_331225_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 569.0
CMS2_k127_331225_1 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 354.0
CMS2_k127_331225_2 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 359.0
CMS2_k127_331225_3 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000004495 256.0
CMS2_k127_331225_4 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000008018 159.0
CMS2_k127_3477145_0 orn lys arg decarboxylase K01584 - 4.1.1.19 0.0 1279.0
CMS2_k127_3477145_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.655e-312 968.0
CMS2_k127_3477145_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 576.0
CMS2_k127_3477145_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 352.0
CMS2_k127_3477145_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 319.0
CMS2_k127_3477145_13 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 320.0
CMS2_k127_3477145_14 Type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 312.0
CMS2_k127_3477145_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 302.0
CMS2_k127_3477145_16 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 310.0
CMS2_k127_3477145_17 Prolyl 4-hydroxylase, alpha subunit K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 309.0
CMS2_k127_3477145_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 298.0
CMS2_k127_3477145_19 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000357 266.0
CMS2_k127_3477145_2 acetolactate synthase K01652 - 2.2.1.6 1.654e-301 937.0
CMS2_k127_3477145_20 pilus assembly protein K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006022 271.0
CMS2_k127_3477145_21 RNA polymerase K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008049 265.0
CMS2_k127_3477145_22 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000002589 274.0
CMS2_k127_3477145_23 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000001343 250.0
CMS2_k127_3477145_24 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000004294 256.0
CMS2_k127_3477145_25 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000009379 240.0
CMS2_k127_3477145_26 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002201 237.0
CMS2_k127_3477145_27 PFAM Hemolysin-type calcium-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000009656 231.0
CMS2_k127_3477145_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000365 195.0
CMS2_k127_3477145_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000003597 170.0
CMS2_k127_3477145_3 Catalyzes the transfer of electrons from NADH to ubiquinone K00336 - 1.6.5.3 1.365e-296 951.0
CMS2_k127_3477145_30 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000001813 112.0
CMS2_k127_3477145_31 TadE-like protein - - - 0.0000000000000000000000003718 108.0
CMS2_k127_3477145_32 RDD family - - - 0.000000000000000000002387 107.0
CMS2_k127_3477145_33 LytR cell envelope-related transcriptional attenuator - - - 0.0000000000000000001753 102.0
CMS2_k127_3477145_34 Protein of unknown function (DUF3106) - - - 0.0000000000000000003381 99.0
CMS2_k127_3477145_35 Protein of unknown function (DUF3619) - - - 0.0000000000009492 79.0
CMS2_k127_3477145_36 Resolvase, N terminal domain - - - 0.00001516 49.0
CMS2_k127_3477145_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 3.925e-244 768.0
CMS2_k127_3477145_5 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.138e-243 761.0
CMS2_k127_3477145_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 7.394e-239 753.0
CMS2_k127_3477145_7 Type II/IV secretion system protein K02283 - - 7.716e-195 616.0
CMS2_k127_3477145_8 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 581.0
CMS2_k127_3477145_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 578.0
CMS2_k127_3494610_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.0 1081.0
CMS2_k127_3494610_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 8.785e-318 997.0
CMS2_k127_3494610_10 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 376.0
CMS2_k127_3494610_11 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 356.0
CMS2_k127_3494610_12 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 320.0
CMS2_k127_3494610_13 Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 317.0
CMS2_k127_3494610_14 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 325.0
CMS2_k127_3494610_15 Fumarate K01678,K03780 - 4.2.1.2,4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 296.0
CMS2_k127_3494610_16 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001438 286.0
CMS2_k127_3494610_17 transcriptional K03710 - - 0.000000000000000000000000000000000000000000000000000000000000004725 228.0
CMS2_k127_3494610_18 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000001374 221.0
CMS2_k127_3494610_19 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000007966 199.0
CMS2_k127_3494610_2 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 5.039e-280 880.0
CMS2_k127_3494610_20 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000000002297 192.0
CMS2_k127_3494610_21 SAF domain K16845 - 4.4.1.24 0.00000000000000000000000000000000000000006916 153.0
CMS2_k127_3494610_22 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00247 - - 0.00000000000000000000000000000000002596 156.0
CMS2_k127_3494610_23 Regulatory protein, FmdB family - - - 0.000000000000000000000009554 107.0
CMS2_k127_3494610_24 succinate dehydrogenase K00246 - - 0.00000000000000000002017 96.0
CMS2_k127_3494610_3 D-galactarate dehydratase / Altronate hydrolase, C terminus K16846,K16850 - 4.2.1.7,4.4.1.24 2.785e-213 669.0
CMS2_k127_3494610_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 561.0
CMS2_k127_3494610_5 Fumarate hydratase (Fumerase) K03779 - 4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 447.0
CMS2_k127_3494610_6 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 413.0
CMS2_k127_3494610_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 381.0
CMS2_k127_3494610_8 Belongs to the LDH2 MDH2 oxidoreductase family K13609,K16844 - 1.1.1.338,1.5.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 394.0
CMS2_k127_3494610_9 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 370.0
CMS2_k127_3518709_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.376e-196 619.0
CMS2_k127_3518709_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 542.0
CMS2_k127_3518709_10 Cupin domain - - - 0.00000000000000000000000000000000000000000006277 168.0
CMS2_k127_3518709_12 Zinc-finger domain - - - 0.0000000000000000002918 100.0
CMS2_k127_3518709_13 Belongs to the 'phage' integrase family - - - 0.0000000000000007402 81.0
CMS2_k127_3518709_14 helix_turn_helix, Lux Regulon - - - 0.00004449 52.0
CMS2_k127_3518709_2 TRAP dicarboxylate transporter K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 423.0
CMS2_k127_3518709_3 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 380.0
CMS2_k127_3518709_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 337.0
CMS2_k127_3518709_5 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004182 275.0
CMS2_k127_3518709_6 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000003081 240.0
CMS2_k127_3518709_7 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003023 241.0
CMS2_k127_3518709_8 Tripartite ATP-independent periplasmic transporter, DctQ - - - 0.000000000000000000000000000000000000000000000000000000000495 211.0
CMS2_k127_3518709_9 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000000003448 169.0
CMS2_k127_3696781_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1204.0
CMS2_k127_3696781_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 3.825e-266 835.0
CMS2_k127_3696781_10 Cytochrome B561 - - - 0.0000000000000000000000000000000000000000000000000000000000000004414 226.0
CMS2_k127_3696781_11 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000000000000001738 211.0
CMS2_k127_3696781_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000001521 216.0
CMS2_k127_3696781_13 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000000006625 150.0
CMS2_k127_3696781_14 PFAM cytochrome c - - - 0.00000000000000000000000000000009528 134.0
CMS2_k127_3696781_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 4.472e-263 818.0
CMS2_k127_3696781_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 4.454e-205 644.0
CMS2_k127_3696781_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.988e-203 641.0
CMS2_k127_3696781_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 562.0
CMS2_k127_3696781_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 461.0
CMS2_k127_3696781_7 PFAM Mg2 transporter protein, CorA family protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 297.0
CMS2_k127_3696781_8 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002076 278.0
CMS2_k127_3696781_9 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006097 226.0
CMS2_k127_3899318_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1490.0
CMS2_k127_3899318_1 PFAM ATP-binding region, ATPase domain protein - - - 1.761e-199 652.0
CMS2_k127_3899318_2 response regulator K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000001797 229.0
CMS2_k127_3899318_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000003547 66.0
CMS2_k127_3951301_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000279 226.0
CMS2_k127_3951301_1 TIGRFAM death-on-curing family protein K07341 - - 0.000000000000000000000000002222 112.0
CMS2_k127_3951301_2 - - - - 0.00000000000003573 84.0
CMS2_k127_3957104_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01584,K01585 - 4.1.1.19 0.0 1084.0
CMS2_k127_3957104_1 Biotin carboxylase - - - 4.309e-223 757.0
CMS2_k127_3957104_2 Choloylglycine hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 426.0
CMS2_k127_3957104_3 transport system fused permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 417.0
CMS2_k127_3957104_4 Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates K01426,K01455,K18540 - 3.5.1.100,3.5.1.4,3.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 414.0
CMS2_k127_3957104_5 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000482 247.0
CMS2_k127_3957104_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000005523 247.0
CMS2_k127_3957104_7 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000004 147.0
CMS2_k127_4022821_0 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.358e-213 668.0
CMS2_k127_4022821_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 535.0
CMS2_k127_4022821_2 PFAM Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000001384 183.0
CMS2_k127_403338_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1543.0
CMS2_k127_403338_1 Pfam:DUF1446 - - - 5.777e-238 743.0
CMS2_k127_403338_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005883 273.0
CMS2_k127_403338_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000001011 172.0
CMS2_k127_403338_4 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000008265 167.0
CMS2_k127_403338_5 Domain of unknown function (DUF4387) - - - 0.0000000000000000000000000000000000000009445 168.0
CMS2_k127_405519_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1094.0
CMS2_k127_405519_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.329e-297 923.0
CMS2_k127_405519_10 PFAM LrgB family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 298.0
CMS2_k127_405519_11 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000006975 229.0
CMS2_k127_405519_12 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000004275 164.0
CMS2_k127_405519_13 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000000000002958 122.0
CMS2_k127_405519_15 membrane - - - 0.00000000000000000000000000002343 121.0
CMS2_k127_405519_16 PFAM LrgA family protein K06518 - - 0.0000000000000000000002534 103.0
CMS2_k127_405519_17 membrane - - - 0.0000000000000008213 82.0
CMS2_k127_405519_2 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 2.38e-235 738.0
CMS2_k127_405519_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 2.449e-210 657.0
CMS2_k127_405519_4 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 559.0
CMS2_k127_405519_5 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 483.0
CMS2_k127_405519_6 TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 465.0
CMS2_k127_405519_7 FAD binding K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 413.0
CMS2_k127_405519_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 306.0
CMS2_k127_405519_9 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 302.0
CMS2_k127_4057862_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1443.0
CMS2_k127_4057862_1 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 4.534e-251 779.0
CMS2_k127_4057862_10 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 467.0
CMS2_k127_4057862_11 PFAM Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 454.0
CMS2_k127_4057862_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 451.0
CMS2_k127_4057862_13 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 393.0
CMS2_k127_4057862_14 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 392.0
CMS2_k127_4057862_15 Alpha beta hydrolase K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 370.0
CMS2_k127_4057862_16 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 336.0
CMS2_k127_4057862_17 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 342.0
CMS2_k127_4057862_18 periplasmic protein TonB K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 320.0
CMS2_k127_4057862_19 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 325.0
CMS2_k127_4057862_2 ribonuclease II K01147 - 3.1.13.1 1.177e-212 680.0
CMS2_k127_4057862_20 abc transporter K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 324.0
CMS2_k127_4057862_21 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 295.0
CMS2_k127_4057862_22 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001468 275.0
CMS2_k127_4057862_23 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002675 295.0
CMS2_k127_4057862_24 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005627 284.0
CMS2_k127_4057862_25 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005667 242.0
CMS2_k127_4057862_26 Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003598 240.0
CMS2_k127_4057862_27 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000004066 226.0
CMS2_k127_4057862_28 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000048 217.0
CMS2_k127_4057862_29 Cobalamin-independent synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001937 227.0
CMS2_k127_4057862_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.467e-209 660.0
CMS2_k127_4057862_30 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000003118 230.0
CMS2_k127_4057862_31 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000005812 200.0
CMS2_k127_4057862_32 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000001737 190.0
CMS2_k127_4057862_33 mRNA catabolic process - - - 0.00000000000000000000000000000000000000000165 178.0
CMS2_k127_4057862_34 Thioredoxin-like - - - 0.0000000000000000000000000000000000001148 156.0
CMS2_k127_4057862_35 Protein of unknown function (DUF2946) - - - 0.0000000000000000000000000000000000309 142.0
CMS2_k127_4057862_36 SnoaL-like domain - - - 0.00000000000000000000000000000001524 132.0
CMS2_k127_4057862_37 YGGT family K02221 - - 0.00000000000000000000000000000001703 133.0
CMS2_k127_4057862_38 Protein of unknown function (DUF3426) - - - 0.000000000000000000001482 110.0
CMS2_k127_4057862_39 Histone H1-like nucleoprotein HC2 K11275 - - 0.00000000000738 72.0
CMS2_k127_4057862_4 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 1.513e-205 644.0
CMS2_k127_4057862_5 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 594.0
CMS2_k127_4057862_6 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 588.0
CMS2_k127_4057862_7 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 567.0
CMS2_k127_4057862_8 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 511.0
CMS2_k127_4057862_9 Sigma-54 interaction domain K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 516.0
CMS2_k127_4072001_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.81e-308 953.0
CMS2_k127_4072001_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.759e-270 853.0
CMS2_k127_4072001_10 Major Facilitator K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 594.0
CMS2_k127_4072001_11 ATP synthase alpha/beta chain, C terminal domain K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 598.0
CMS2_k127_4072001_12 TIGRFAM Drug resistance transporter Bcr CflA subfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 571.0
CMS2_k127_4072001_13 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 548.0
CMS2_k127_4072001_14 quinone oxidoreductase, YhdH YhfP family K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 493.0
CMS2_k127_4072001_15 Soluble lytic murein K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 501.0
CMS2_k127_4072001_16 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 473.0
CMS2_k127_4072001_17 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01032 - 2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 460.0
CMS2_k127_4072001_18 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 455.0
CMS2_k127_4072001_19 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 433.0
CMS2_k127_4072001_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 2.149e-243 759.0
CMS2_k127_4072001_20 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 383.0
CMS2_k127_4072001_21 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 378.0
CMS2_k127_4072001_22 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 375.0
CMS2_k127_4072001_23 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 374.0
CMS2_k127_4072001_24 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 362.0
CMS2_k127_4072001_25 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 360.0
CMS2_k127_4072001_26 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 377.0
CMS2_k127_4072001_27 Phosphotransferase enzyme family K00899 - 2.7.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 364.0
CMS2_k127_4072001_28 Domain of unknown function (DUF3391) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 363.0
CMS2_k127_4072001_29 NAD dependent epimerase dehydratase family protein K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 346.0
CMS2_k127_4072001_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 7.679e-218 687.0
CMS2_k127_4072001_30 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 319.0
CMS2_k127_4072001_31 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 320.0
CMS2_k127_4072001_32 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 320.0
CMS2_k127_4072001_33 Domain of unknown function (DUF3391) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 315.0
CMS2_k127_4072001_34 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 308.0
CMS2_k127_4072001_35 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 312.0
CMS2_k127_4072001_36 ATP synthase A chain K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 301.0
CMS2_k127_4072001_37 acetyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 298.0
CMS2_k127_4072001_38 lipid A biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 306.0
CMS2_k127_4072001_39 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 294.0
CMS2_k127_4072001_4 phosphorelay signal transduction system K12132 - 2.7.11.1 4.698e-215 691.0
CMS2_k127_4072001_40 Flavin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002159 306.0
CMS2_k127_4072001_41 ChaC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003416 282.0
CMS2_k127_4072001_42 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001234 272.0
CMS2_k127_4072001_43 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007713 271.0
CMS2_k127_4072001_44 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003787 262.0
CMS2_k127_4072001_45 RNA-binding S4 domain-containing protein K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000003894 263.0
CMS2_k127_4072001_46 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007634 252.0
CMS2_k127_4072001_47 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000004843 256.0
CMS2_k127_4072001_48 TIGRFAM alternate F1F0 ATPase, F1 subunit gamma K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006606 256.0
CMS2_k127_4072001_49 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006381 258.0
CMS2_k127_4072001_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 5.792e-214 670.0
CMS2_k127_4072001_50 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000001874 232.0
CMS2_k127_4072001_51 PFAM Taurine catabolism dioxygenase TauD TfdA K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000002721 229.0
CMS2_k127_4072001_52 Metal dependent phosphohydrolases with conserved 'HD' motif. K21196 - 1.13.11.78 0.000000000000000000000000000000000000000000000000000000000000008316 222.0
CMS2_k127_4072001_53 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000004264 215.0
CMS2_k127_4072001_54 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000002608 201.0
CMS2_k127_4072001_55 Transcriptional regulator K03566 - - 0.000000000000000000000000000000000000000000000000000003093 204.0
CMS2_k127_4072001_56 - - - - 0.00000000000000000000000000000000000000000000000006189 204.0
CMS2_k127_4072001_57 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000004797 184.0
CMS2_k127_4072001_58 ATP synthase B/B' CF(0) K02109 - - 0.00000000000000000000000000000000000000001307 162.0
CMS2_k127_4072001_59 - - - - 0.0000000000000000000000000000000000000006323 150.0
CMS2_k127_4072001_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 1.551e-209 659.0
CMS2_k127_4072001_60 OsmC-like protein - - - 0.00000000000000000000000000000000000001464 151.0
CMS2_k127_4072001_61 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.0000000000000000000000000000000000003033 145.0
CMS2_k127_4072001_62 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000003043 156.0
CMS2_k127_4072001_63 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000001481 142.0
CMS2_k127_4072001_64 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000001967 143.0
CMS2_k127_4072001_65 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000009851 138.0
CMS2_k127_4072001_66 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000001423 131.0
CMS2_k127_4072001_67 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000007416 141.0
CMS2_k127_4072001_68 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000002232 131.0
CMS2_k127_4072001_69 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000000000000001024 118.0
CMS2_k127_4072001_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.758e-205 659.0
CMS2_k127_4072001_70 - - - - 0.00000000000000000002296 104.0
CMS2_k127_4072001_71 Protein of unknown function (DUF2905) - - - 0.000000000000000001425 88.0
CMS2_k127_4072001_72 heavy metal K07213 - - 0.000000000000000102 81.0
CMS2_k127_4072001_73 Helix-hairpin-helix motif - - - 0.000000000000001453 83.0
CMS2_k127_4072001_74 TIGRFAM F1 F0 ATPase, Methanosarcina type, subunit 2 - - - 0.0000001901 57.0
CMS2_k127_4072001_75 - - - - 0.000001753 57.0
CMS2_k127_4072001_76 - - - - 0.00005887 53.0
CMS2_k127_4072001_8 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 598.0
CMS2_k127_4072001_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 600.0
CMS2_k127_4090629_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00244 - 1.3.5.4 8.919e-293 907.0
CMS2_k127_4090629_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.262e-287 923.0
CMS2_k127_4090629_10 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.514e-204 657.0
CMS2_k127_4090629_100 Type II transport protein GspH K08084,K08085 - - 0.0000000000000000000001963 106.0
CMS2_k127_4090629_101 - - - - 0.000000000000000000007831 104.0
CMS2_k127_4090629_102 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000005263 95.0
CMS2_k127_4090629_103 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000003103 85.0
CMS2_k127_4090629_105 - - - - 0.0000000788 64.0
CMS2_k127_4090629_107 Sporulation domain protein - - - 0.00004198 55.0
CMS2_k127_4090629_11 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 6.54e-203 649.0
CMS2_k127_4090629_12 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 5.648e-198 641.0
CMS2_k127_4090629_13 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 617.0
CMS2_k127_4090629_14 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 614.0
CMS2_k127_4090629_15 PFAM phenylacetic acid catabolic family protein K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 560.0
CMS2_k127_4090629_16 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 551.0
CMS2_k127_4090629_17 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 540.0
CMS2_k127_4090629_18 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 526.0
CMS2_k127_4090629_19 COG2951 Membrane-bound lytic murein transglycosylase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 539.0
CMS2_k127_4090629_2 DNA helicase K03654 - 3.6.4.12 1.663e-262 824.0
CMS2_k127_4090629_20 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 516.0
CMS2_k127_4090629_21 TIGRFAM phenylacetate-CoA oxygenase reductase, PaaK subunit K02613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 512.0
CMS2_k127_4090629_22 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 504.0
CMS2_k127_4090629_23 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 508.0
CMS2_k127_4090629_24 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 511.0
CMS2_k127_4090629_25 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 494.0
CMS2_k127_4090629_26 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 491.0
CMS2_k127_4090629_27 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 512.0
CMS2_k127_4090629_28 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 491.0
CMS2_k127_4090629_29 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 495.0
CMS2_k127_4090629_3 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 1.562e-254 803.0
CMS2_k127_4090629_30 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 485.0
CMS2_k127_4090629_31 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 474.0
CMS2_k127_4090629_32 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 462.0
CMS2_k127_4090629_33 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 446.0
CMS2_k127_4090629_34 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 447.0
CMS2_k127_4090629_35 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 443.0
CMS2_k127_4090629_36 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 405.0
CMS2_k127_4090629_37 DegT/DnrJ/EryC1/StrS aminotransferase family K00812,K12252 - 2.6.1.1,2.6.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 411.0
CMS2_k127_4090629_38 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 406.0
CMS2_k127_4090629_39 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 402.0
CMS2_k127_4090629_4 AMP-binding enzyme K01897 - 6.2.1.3 9.28e-253 793.0
CMS2_k127_4090629_40 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 406.0
CMS2_k127_4090629_41 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 397.0
CMS2_k127_4090629_42 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 414.0
CMS2_k127_4090629_43 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 357.0
CMS2_k127_4090629_44 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 349.0
CMS2_k127_4090629_45 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 347.0
CMS2_k127_4090629_46 Von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 346.0
CMS2_k127_4090629_47 proteins homologs of microcin C7 resistance protein MccF K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 335.0
CMS2_k127_4090629_48 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 361.0
CMS2_k127_4090629_49 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 321.0
CMS2_k127_4090629_5 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 4.902e-249 775.0
CMS2_k127_4090629_50 Permeases of the drug metabolite transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 321.0
CMS2_k127_4090629_51 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 320.0
CMS2_k127_4090629_52 phenylacetic acid K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 327.0
CMS2_k127_4090629_53 Thioredoxin K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 306.0
CMS2_k127_4090629_54 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 290.0
CMS2_k127_4090629_55 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001769 274.0
CMS2_k127_4090629_56 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003456 271.0
CMS2_k127_4090629_57 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008832 275.0
CMS2_k127_4090629_58 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003035 269.0
CMS2_k127_4090629_59 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000005275 266.0
CMS2_k127_4090629_6 Arginyl-tRNA synthetase K01887 - 6.1.1.19 3.675e-245 770.0
CMS2_k127_4090629_60 Pilus assembly protein PilX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006287 261.0
CMS2_k127_4090629_61 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006725 271.0
CMS2_k127_4090629_62 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001177 247.0
CMS2_k127_4090629_63 Alpha beta K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001794 253.0
CMS2_k127_4090629_64 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007737 243.0
CMS2_k127_4090629_65 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000409 236.0
CMS2_k127_4090629_66 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000002152 224.0
CMS2_k127_4090629_67 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000007621 227.0
CMS2_k127_4090629_68 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000006791 222.0
CMS2_k127_4090629_69 type IV pilus modification protein PilV - - - 0.0000000000000000000000000000000000000000000000000000000000002252 227.0
CMS2_k127_4090629_7 synthetase K01907 - 6.2.1.16 3.12e-237 751.0
CMS2_k127_4090629_70 hydroperoxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000002716 210.0
CMS2_k127_4090629_71 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000002812 229.0
CMS2_k127_4090629_72 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000008246 211.0
CMS2_k127_4090629_73 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000002647 209.0
CMS2_k127_4090629_74 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000005241 204.0
CMS2_k127_4090629_75 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000001069 205.0
CMS2_k127_4090629_76 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000001299 190.0
CMS2_k127_4090629_77 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000002649 184.0
CMS2_k127_4090629_78 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000000000000000000000005859 186.0
CMS2_k127_4090629_79 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000278 191.0
CMS2_k127_4090629_8 4-coumarate--CoA K01179 - 3.2.1.4 1.257e-236 745.0
CMS2_k127_4090629_80 TIGRFAM phenylacetate-CoA oxygenase, PaaH subunit K02610 - - 0.000000000000000000000000000000000000000000000005694 173.0
CMS2_k127_4090629_81 phenylacetate-CoA oxygenase, PaaJ subunit K02612 GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000008592 186.0
CMS2_k127_4090629_82 PFAM regulatory protein TetR K09017 - - 0.000000000000000000000000000000000000000000000196 175.0
CMS2_k127_4090629_83 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000001712 171.0
CMS2_k127_4090629_84 VanZ like family - - - 0.000000000000000000000000000000000000000001816 173.0
CMS2_k127_4090629_85 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000003802 154.0
CMS2_k127_4090629_86 PIN domain K07064 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000009664 150.0
CMS2_k127_4090629_87 Ferredoxin - - - 0.00000000000000000000000000000000000001741 164.0
CMS2_k127_4090629_88 Thioredoxin-like - - - 0.000000000000000000000000000000000007041 153.0
CMS2_k127_4090629_89 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 - - 0.00000000000000000000000000000007831 134.0
CMS2_k127_4090629_9 Sodium:solute symporter family - - - 1.612e-226 711.0
CMS2_k127_4090629_90 Sporulation related domain - - - 0.0000000000000000000000000000001526 133.0
CMS2_k127_4090629_91 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000003683 135.0
CMS2_k127_4090629_92 Fumarate reductase subunit C K00246 - - 0.00000000000000000000000000001601 123.0
CMS2_k127_4090629_93 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 0.00000000000000000000000000003991 127.0
CMS2_k127_4090629_94 Domain of unknown function (DUF1508) K09946 - - 0.000000000000000000000000000123 120.0
CMS2_k127_4090629_95 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000000000001902 120.0
CMS2_k127_4090629_96 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000002907 124.0
CMS2_k127_4090629_97 Prokaryotic N-terminal methylation motif K02680 - - 0.000000000000000000000000001329 126.0
CMS2_k127_4090629_98 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000002311 110.0
CMS2_k127_4090629_99 Cysteine-rich secretory protein family - - - 0.00000000000000000000009049 107.0
CMS2_k127_4130703_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.505e-282 890.0
CMS2_k127_4130703_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.259e-234 754.0
CMS2_k127_4130703_10 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000276 247.0
CMS2_k127_4130703_11 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000002816 241.0
CMS2_k127_4130703_12 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000008749 258.0
CMS2_k127_4130703_13 Plasmid maintenance system killer K07334 - - 0.00000000000000000000000000000000000000000000000007913 178.0
CMS2_k127_4130703_14 antidote protein K21498 - - 0.00000000000000000000000000000000000000000000002871 172.0
CMS2_k127_4130703_15 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000421 118.0
CMS2_k127_4130703_16 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000003499 116.0
CMS2_k127_4130703_17 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000008544 101.0
CMS2_k127_4130703_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 565.0
CMS2_k127_4130703_3 Bacterial sugar transferase K21303 - 2.7.8.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 449.0
CMS2_k127_4130703_4 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 434.0
CMS2_k127_4130703_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 358.0
CMS2_k127_4130703_6 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 328.0
CMS2_k127_4130703_7 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 312.0
CMS2_k127_4130703_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008958 264.0
CMS2_k127_4130703_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000002975 260.0
CMS2_k127_4152243_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1047.0
CMS2_k127_4152243_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 3.144e-308 966.0
CMS2_k127_4152243_10 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000004992 179.0
CMS2_k127_4152243_11 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000005917 174.0
CMS2_k127_4152243_12 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000000005579 116.0
CMS2_k127_4152243_13 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000005074 94.0
CMS2_k127_4152243_14 Domain of unknown function (DUF4105) - - - 0.00000000000005435 76.0
CMS2_k127_4152243_15 dehydrogenase - - - 0.0002817 44.0
CMS2_k127_4152243_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 501.0
CMS2_k127_4152243_3 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 441.0
CMS2_k127_4152243_4 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 428.0
CMS2_k127_4152243_5 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 319.0
CMS2_k127_4152243_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003456 271.0
CMS2_k127_4152243_7 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004362 237.0
CMS2_k127_4152243_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000001519 193.0
CMS2_k127_4152243_9 - - - - 0.000000000000000000000000000000000000000000000000003724 183.0
CMS2_k127_4171597_0 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000000000000000000000007475 200.0
CMS2_k127_4171597_1 Protein of unknown function (DUF4242) - - - 0.0000000000002736 74.0
CMS2_k127_4171597_2 - - - - 0.0000003449 61.0
CMS2_k127_4171597_3 Helix-turn-helix domain - - - 0.0007889 49.0
CMS2_k127_4180513_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1235.0
CMS2_k127_4180513_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1217.0
CMS2_k127_4180513_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002347 261.0
CMS2_k127_4180513_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003377 238.0
CMS2_k127_4180513_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000003372 87.0
CMS2_k127_4226515_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1596.0
CMS2_k127_4226515_1 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 1.302e-242 755.0
CMS2_k127_4226515_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18145 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 388.0
CMS2_k127_4226515_3 protein conserved in bacteria - - - 0.0000000000000000000000003078 110.0
CMS2_k127_4226515_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000002796 75.0
CMS2_k127_4251547_0 Dehydrogenase K15371 - 1.4.1.2 2.955e-263 841.0
CMS2_k127_4251547_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K00836,K07250 - 2.6.1.19,2.6.1.22,2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 420.0
CMS2_k127_4404838_0 Putative nucleotide-binding of sugar-metabolising enzyme K21948 - 2.7.1.217 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 546.0
CMS2_k127_4404838_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 402.0
CMS2_k127_4404838_2 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.000000000000000000000000000000000000000000000133 172.0
CMS2_k127_4420225_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.425e-265 833.0
CMS2_k127_4420225_1 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 406.0
CMS2_k127_4420225_2 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 349.0
CMS2_k127_4436745_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1272.0
CMS2_k127_4436745_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1202.0
CMS2_k127_4436745_10 AMP-binding enzyme K12508 - 6.2.1.34 5.967e-243 796.0
CMS2_k127_4436745_11 Peptidase family M20/M25/M40 - - - 2.212e-225 722.0
CMS2_k127_4436745_12 multicopper oxidase type 3 K22348 - 1.16.3.3 1.008e-222 701.0
CMS2_k127_4436745_13 Thymidine phosphorylase K00758 - 2.4.2.4 5.824e-222 714.0
CMS2_k127_4436745_14 L-carnitine dehydratase bile acid-inducible protein F - - - 4.7e-198 625.0
CMS2_k127_4436745_15 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 8.676e-195 636.0
CMS2_k127_4436745_16 Belongs to the thiolase family - - - 8.976e-194 614.0
CMS2_k127_4436745_17 COG1840 ABC-type Fe3 transport system, periplasmic component K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 600.0
CMS2_k127_4436745_18 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 603.0
CMS2_k127_4436745_19 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 587.0
CMS2_k127_4436745_2 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K09461 - 1.14.13.40 0.0 1196.0
CMS2_k127_4436745_20 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 570.0
CMS2_k127_4436745_21 PFAM aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 549.0
CMS2_k127_4436745_22 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 547.0
CMS2_k127_4436745_23 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 546.0
CMS2_k127_4436745_24 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 550.0
CMS2_k127_4436745_25 Belongs to the ABC transporter superfamily K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 530.0
CMS2_k127_4436745_26 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 556.0
CMS2_k127_4436745_27 Biotin carboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 525.0
CMS2_k127_4436745_28 PFAM Cupin 2, conserved barrel domain protein K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 497.0
CMS2_k127_4436745_29 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 494.0
CMS2_k127_4436745_3 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0 1058.0
CMS2_k127_4436745_30 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 484.0
CMS2_k127_4436745_31 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 445.0
CMS2_k127_4436745_32 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 433.0
CMS2_k127_4436745_33 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 434.0
CMS2_k127_4436745_34 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 425.0
CMS2_k127_4436745_35 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 416.0
CMS2_k127_4436745_36 Glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 404.0
CMS2_k127_4436745_37 S-adenosyl-L-homocysteine hydrolase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 419.0
CMS2_k127_4436745_38 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 385.0
CMS2_k127_4436745_39 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 374.0
CMS2_k127_4436745_4 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.887e-318 1020.0
CMS2_k127_4436745_40 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008509 368.0
CMS2_k127_4436745_41 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 362.0
CMS2_k127_4436745_42 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 362.0
CMS2_k127_4436745_43 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 366.0
CMS2_k127_4436745_44 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 381.0
CMS2_k127_4436745_45 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 365.0
CMS2_k127_4436745_46 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 364.0
CMS2_k127_4436745_47 Haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 352.0
CMS2_k127_4436745_48 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 319.0
CMS2_k127_4436745_49 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 322.0
CMS2_k127_4436745_5 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 3.124e-270 847.0
CMS2_k127_4436745_50 response regulator K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 306.0
CMS2_k127_4436745_51 Class II aldolase adducin family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 306.0
CMS2_k127_4436745_52 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 293.0
CMS2_k127_4436745_53 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 311.0
CMS2_k127_4436745_54 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001445 279.0
CMS2_k127_4436745_55 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000549 313.0
CMS2_k127_4436745_56 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001847 277.0
CMS2_k127_4436745_57 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004643 258.0
CMS2_k127_4436745_58 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K16049 - 1.13.11.25 0.0000000000000000000000000000000000000000000000000000000000000000000000004643 258.0
CMS2_k127_4436745_59 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000001324 247.0
CMS2_k127_4436745_6 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 7.451e-259 827.0
CMS2_k127_4436745_60 Protein of unknown function (DUF3750) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009874 255.0
CMS2_k127_4436745_61 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000002954 246.0
CMS2_k127_4436745_62 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000021 236.0
CMS2_k127_4436745_63 response regulator receiver K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000004901 239.0
CMS2_k127_4436745_64 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000009465 241.0
CMS2_k127_4436745_65 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002624 238.0
CMS2_k127_4436745_66 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004333 239.0
CMS2_k127_4436745_67 PFAM CreA family protein K05805 - - 0.0000000000000000000000000000000000000000000000000000000000000000019 230.0
CMS2_k127_4436745_68 Member of a two-component regulatory system K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000003386 248.0
CMS2_k127_4436745_69 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000376 222.0
CMS2_k127_4436745_7 PFAM MmgE PrpD family protein - - - 1.946e-247 768.0
CMS2_k127_4436745_70 metal-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000491 207.0
CMS2_k127_4436745_71 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000003346 210.0
CMS2_k127_4436745_72 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.00000000000000000000000000000000000000000000000000005471 191.0
CMS2_k127_4436745_73 FCD - - - 0.000000000000000000000000000000000000000000000000001306 191.0
CMS2_k127_4436745_74 2Fe-2S -binding domain protein K03518,K13483 - 1.2.5.3 0.00000000000000000000000000000000000000000000000004325 183.0
CMS2_k127_4436745_75 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000000000000000000000000000000000001236 183.0
CMS2_k127_4436745_77 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000392 160.0
CMS2_k127_4436745_78 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000000000005622 181.0
CMS2_k127_4436745_79 - - - - 0.000000000000000000000000000000000000000002575 157.0
CMS2_k127_4436745_8 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 6.509e-246 771.0
CMS2_k127_4436745_80 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000007544 169.0
CMS2_k127_4436745_81 Protein of unknown function (DUF2505) - - - 0.00000000000000000000000000000000000000005729 160.0
CMS2_k127_4436745_82 nitric oxide dioxygenase activity - - - 0.0000000000000000000000000000000000000001828 155.0
CMS2_k127_4436745_83 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000002074 158.0
CMS2_k127_4436745_84 YhhN family - - - 0.0000000000000000000000000000000000000002916 170.0
CMS2_k127_4436745_85 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000000000000267 164.0
CMS2_k127_4436745_86 Pfam cytochrome c K08738 - - 0.000000000000000000000000000000000007645 139.0
CMS2_k127_4436745_87 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000002653 143.0
CMS2_k127_4436745_88 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000009129 127.0
CMS2_k127_4436745_89 Copper binding periplasmic protein CusF - - - 0.0000000000000000000000001008 109.0
CMS2_k127_4436745_9 Cytochrome c554 and c-prime - - - 1.393e-244 779.0
CMS2_k127_4436745_92 - - - - 0.000000000000000204 89.0
CMS2_k127_4436745_93 Short C-terminal domain K08982 - - 0.00000000000002515 76.0
CMS2_k127_4444510_0 Domain of unknown function (DUF3394) - - - 1.567e-317 984.0
CMS2_k127_4444510_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 586.0
CMS2_k127_4444510_10 PIN domain K07064 - - 0.000000000000000000004608 98.0
CMS2_k127_4444510_11 Transcriptional regulator K07172 - - 0.00000000000000000005206 93.0
CMS2_k127_4444510_12 aspartic-type endopeptidase activity K06985 - - 0.00000000000000000009967 95.0
CMS2_k127_4444510_13 Cupin 2, conserved barrel domain protein - - - 0.000000000000000004422 88.0
CMS2_k127_4444510_15 Fe-S-cluster oxidoreductase K06940 - - 0.00002703 46.0
CMS2_k127_4444510_2 Integral membrane protein TerC family K05794 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 514.0
CMS2_k127_4444510_3 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 316.0
CMS2_k127_4444510_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 302.0
CMS2_k127_4444510_5 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000000001385 145.0
CMS2_k127_4444510_6 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000008054 151.0
CMS2_k127_4444510_7 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000000000002684 144.0
CMS2_k127_4444510_8 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000005997 141.0
CMS2_k127_4444510_9 TIGRFAM phasin family protein - - - 0.000000000000000000000000000001057 128.0
CMS2_k127_4446472_0 - - - - 1.592e-314 1001.0
CMS2_k127_4446472_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.069e-277 882.0
CMS2_k127_4446472_10 Tripartite tricarboxylate transporter TctA family K07793 - - 4.641e-212 669.0
CMS2_k127_4446472_11 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 5.267e-209 659.0
CMS2_k127_4446472_12 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.302e-208 661.0
CMS2_k127_4446472_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00457 - 1.13.11.27 2.064e-195 614.0
CMS2_k127_4446472_14 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 584.0
CMS2_k127_4446472_15 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 567.0
CMS2_k127_4446472_16 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 556.0
CMS2_k127_4446472_17 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 529.0
CMS2_k127_4446472_18 fumarate reductase succinate dehydrogenase flavoprotein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 586.0
CMS2_k127_4446472_19 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 512.0
CMS2_k127_4446472_2 xanthine dehydrogenase activity K04108 - 1.3.7.9 1.981e-267 856.0
CMS2_k127_4446472_20 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 500.0
CMS2_k127_4446472_21 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 483.0
CMS2_k127_4446472_22 Putative serine dehydratase domain K20757 - 4.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 475.0
CMS2_k127_4446472_23 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 488.0
CMS2_k127_4446472_24 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 468.0
CMS2_k127_4446472_25 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 446.0
CMS2_k127_4446472_26 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 462.0
CMS2_k127_4446472_27 COG2871 Na -transporting NADH ubiquinone oxidoreductase, subunit NqrF K00351,K16246 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 427.0
CMS2_k127_4446472_28 Sigma-54 interaction domain K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 421.0
CMS2_k127_4446472_29 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 401.0
CMS2_k127_4446472_3 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 4.048e-261 818.0
CMS2_k127_4446472_30 Fumarylacetoacetate (FAA) hydrolase family K02509 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 393.0
CMS2_k127_4446472_31 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 394.0
CMS2_k127_4446472_32 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 385.0
CMS2_k127_4446472_33 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 379.0
CMS2_k127_4446472_34 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 389.0
CMS2_k127_4446472_35 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 390.0
CMS2_k127_4446472_36 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 372.0
CMS2_k127_4446472_37 lipopolysaccharide heptosyltransferase I K02841,K12982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 383.0
CMS2_k127_4446472_38 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 361.0
CMS2_k127_4446472_39 Bacterial extracellular solute-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 349.0
CMS2_k127_4446472_4 Belongs to the aldehyde dehydrogenase family K00130,K00151,K10217 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0008802,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 1.835e-259 806.0
CMS2_k127_4446472_40 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 344.0
CMS2_k127_4446472_41 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 307.0
CMS2_k127_4446472_42 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 322.0
CMS2_k127_4446472_43 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 316.0
CMS2_k127_4446472_44 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 316.0
CMS2_k127_4446472_45 protein, hemolysin III K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 286.0
CMS2_k127_4446472_46 Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005686 278.0
CMS2_k127_4446472_47 GDP-mannose 4,6 dehydratase K18981 - 1.1.1.203 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008188 290.0
CMS2_k127_4446472_48 Protein of unknown function (DUF4254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001504 269.0
CMS2_k127_4446472_49 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000006949 263.0
CMS2_k127_4446472_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 1.928e-236 736.0
CMS2_k127_4446472_50 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007332 256.0
CMS2_k127_4446472_51 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002374 278.0
CMS2_k127_4446472_52 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006169 271.0
CMS2_k127_4446472_53 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000003851 263.0
CMS2_k127_4446472_54 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001091 248.0
CMS2_k127_4446472_55 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000005985 260.0
CMS2_k127_4446472_56 COG4662 ABC-type tungstate transport system, periplasmic component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000001132 243.0
CMS2_k127_4446472_57 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000845 266.0
CMS2_k127_4446472_58 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000119 242.0
CMS2_k127_4446472_59 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000007469 238.0
CMS2_k127_4446472_6 COG0210 Superfamily I DNA and RNA helicases K03657 - 3.6.4.12 6.797e-229 730.0
CMS2_k127_4446472_60 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000004345 233.0
CMS2_k127_4446472_61 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006912 229.0
CMS2_k127_4446472_62 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000002897 244.0
CMS2_k127_4446472_63 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000006358 220.0
CMS2_k127_4446472_64 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000001095 223.0
CMS2_k127_4446472_65 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000002811 224.0
CMS2_k127_4446472_66 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.0000000000000000000000000000000000000000000000000000000002034 225.0
CMS2_k127_4446472_67 Protein of unknown function (DUF2953) - - - 0.000000000000000000000000000000000000000000000000000000001374 206.0
CMS2_k127_4446472_68 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000007624 208.0
CMS2_k127_4446472_69 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000002072 205.0
CMS2_k127_4446472_7 ABC-type dipeptide transport system periplasmic component K02035,K13889 - - 1.033e-228 721.0
CMS2_k127_4446472_70 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.000000000000000000000000000000000000000000000001192 175.0
CMS2_k127_4446472_71 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000277 160.0
CMS2_k127_4446472_72 CBS domain - - - 0.0000000000000000000000000000000000005209 146.0
CMS2_k127_4446472_73 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000001463 148.0
CMS2_k127_4446472_74 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000007055 154.0
CMS2_k127_4446472_75 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000008776 146.0
CMS2_k127_4446472_76 Translation initiation factor 1A / IF-1 K02518 - - 0.000000000000000000000000000000005563 135.0
CMS2_k127_4446472_77 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000771 132.0
CMS2_k127_4446472_78 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000001981 130.0
CMS2_k127_4446472_79 thiolester hydrolase activity K17362 - - 0.0000000000000000000000000000009869 139.0
CMS2_k127_4446472_8 COG0471 Di- and tricarboxylate transporters - - - 3.163e-223 710.0
CMS2_k127_4446472_80 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000004198 124.0
CMS2_k127_4446472_81 Cold shock protein K03704 - - 0.00000000000000000000000007925 108.0
CMS2_k127_4446472_82 PspC domain - - - 0.0000000000000000000000001731 109.0
CMS2_k127_4446472_83 Part of a membrane complex involved in electron transport K00347,K03614 - 1.6.5.8 0.0000000000000000000000004194 115.0
CMS2_k127_4446472_84 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000008057 103.0
CMS2_k127_4446472_85 - - - - 0.00000000000000000000001523 103.0
CMS2_k127_4446472_86 Protein of unknown function (DUF998) - - - 0.00000000000000000000003277 109.0
CMS2_k127_4446472_87 - - - - 0.0000000000000000000005702 99.0
CMS2_k127_4446472_88 Cold shock K03704 - - 0.00000000000000000003244 94.0
CMS2_k127_4446472_89 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000001622 89.0
CMS2_k127_4446472_9 Tripartite ATP-independent periplasmic transporter, DctM component - - - 7.564e-213 670.0
CMS2_k127_4446472_90 - - - - 0.0000000000001047 79.0
CMS2_k127_4446472_91 Pas domain - - - 0.000000000001849 81.0
CMS2_k127_4446472_92 Tripartite tricarboxylate transporter TctB family - - - 0.00000000002208 78.0
CMS2_k127_4446472_93 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.0000000001735 70.0
CMS2_k127_4446472_94 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.00000004441 66.0
CMS2_k127_4446472_96 - - - - 0.00006026 50.0
CMS2_k127_4609131_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 601.0
CMS2_k127_4609131_1 Proteasome K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002497 264.0
CMS2_k127_4609131_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000247 66.0
CMS2_k127_4696336_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2333.0
CMS2_k127_4696336_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 6.566e-237 734.0
CMS2_k127_4696336_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 357.0
CMS2_k127_4696336_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 314.0
CMS2_k127_4696336_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003638 271.0
CMS2_k127_4696336_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000007197 224.0
CMS2_k127_4696336_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000001566 194.0
CMS2_k127_4696336_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000000000000000000000000001659 152.0
CMS2_k127_4696336_8 recombinase activity - - - 0.0008483 42.0
CMS2_k127_5017097_0 Quinone oxidoreductase K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 348.0
CMS2_k127_5017097_1 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 312.0
CMS2_k127_5017097_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002816 272.0
CMS2_k127_5045350_0 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 7.618e-283 890.0
CMS2_k127_5045350_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.895e-223 700.0
CMS2_k127_5045350_10 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 339.0
CMS2_k127_5045350_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 342.0
CMS2_k127_5045350_12 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 333.0
CMS2_k127_5045350_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 322.0
CMS2_k127_5045350_14 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 320.0
CMS2_k127_5045350_15 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 312.0
CMS2_k127_5045350_16 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 284.0
CMS2_k127_5045350_17 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000553 288.0
CMS2_k127_5045350_18 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000255 256.0
CMS2_k127_5045350_19 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006291 257.0
CMS2_k127_5045350_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 531.0
CMS2_k127_5045350_20 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000234 248.0
CMS2_k127_5045350_21 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008789 243.0
CMS2_k127_5045350_22 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000659 231.0
CMS2_k127_5045350_23 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000000002682 218.0
CMS2_k127_5045350_24 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000459 222.0
CMS2_k127_5045350_25 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000001093 231.0
CMS2_k127_5045350_26 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000001916 216.0
CMS2_k127_5045350_27 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000000000002017 212.0
CMS2_k127_5045350_28 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000001409 202.0
CMS2_k127_5045350_29 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000002564 199.0
CMS2_k127_5045350_3 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 526.0
CMS2_k127_5045350_30 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000008207 188.0
CMS2_k127_5045350_31 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000000001917 181.0
CMS2_k127_5045350_32 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000006784 172.0
CMS2_k127_5045350_33 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000000002637 171.0
CMS2_k127_5045350_34 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000004673 190.0
CMS2_k127_5045350_35 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000001407 162.0
CMS2_k127_5045350_36 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000000000001053 151.0
CMS2_k127_5045350_37 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000004873 146.0
CMS2_k127_5045350_38 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000008342 145.0
CMS2_k127_5045350_39 Pilus assembly protein K02665 - - 0.0000000000000000000000000000002193 139.0
CMS2_k127_5045350_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 507.0
CMS2_k127_5045350_40 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000002769 119.0
CMS2_k127_5045350_41 Belongs to the frataxin family K06202 - - 0.0000000000000000000216 107.0
CMS2_k127_5045350_42 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000000004806 89.0
CMS2_k127_5045350_43 CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000007756 91.0
CMS2_k127_5045350_44 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000003237 89.0
CMS2_k127_5045350_45 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000773 77.0
CMS2_k127_5045350_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 456.0
CMS2_k127_5045350_6 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 458.0
CMS2_k127_5045350_7 assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 458.0
CMS2_k127_5045350_8 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 392.0
CMS2_k127_5045350_9 PFAM ABC transporter related K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 382.0
CMS2_k127_5178318_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1405.0
CMS2_k127_5178318_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1314.0
CMS2_k127_5178318_10 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 395.0
CMS2_k127_5178318_11 Permease, YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 377.0
CMS2_k127_5178318_12 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 335.0
CMS2_k127_5178318_13 HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 332.0
CMS2_k127_5178318_14 esterase K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 301.0
CMS2_k127_5178318_15 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003666 279.0
CMS2_k127_5178318_16 LysE type translocator K05834 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007624 246.0
CMS2_k127_5178318_17 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000007053 252.0
CMS2_k127_5178318_18 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000454 213.0
CMS2_k127_5178318_19 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.000000000000000000000000000000000000000001481 177.0
CMS2_k127_5178318_2 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 4.685e-267 839.0
CMS2_k127_5178318_20 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000008978 136.0
CMS2_k127_5178318_21 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000003749 133.0
CMS2_k127_5178318_23 TonB family K03832 - - 0.0002327 51.0
CMS2_k127_5178318_3 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 1.66e-227 719.0
CMS2_k127_5178318_4 Tripartite tricarboxylate transporter TctA family - - - 2.472e-226 718.0
CMS2_k127_5178318_5 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 579.0
CMS2_k127_5178318_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 568.0
CMS2_k127_5178318_7 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 521.0
CMS2_k127_5178318_8 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 460.0
CMS2_k127_5178318_9 PFAM Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 410.0
CMS2_k127_5222451_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.812e-271 862.0
CMS2_k127_5222451_1 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 6.703e-235 734.0
CMS2_k127_5222451_10 Aldolase/RraA - - - 0.0000000005776 61.0
CMS2_k127_5222451_2 Protein of unknown function - - - 1.398e-212 709.0
CMS2_k127_5222451_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 570.0
CMS2_k127_5222451_4 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 360.0
CMS2_k127_5222451_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 393.0
CMS2_k127_5222451_6 Carbon-nitrogen hydrolase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 355.0
CMS2_k127_5222451_7 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000001578 257.0
CMS2_k127_5222451_8 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000001933 188.0
CMS2_k127_5222451_9 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000001141 121.0
CMS2_k127_5248655_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1774.0
CMS2_k127_5248655_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1700.0
CMS2_k127_5248655_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 528.0
CMS2_k127_5248655_11 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 502.0
CMS2_k127_5248655_12 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 493.0
CMS2_k127_5248655_13 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 455.0
CMS2_k127_5248655_14 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 452.0
CMS2_k127_5248655_15 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 445.0
CMS2_k127_5248655_16 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 455.0
CMS2_k127_5248655_17 Transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 436.0
CMS2_k127_5248655_18 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 414.0
CMS2_k127_5248655_19 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 420.0
CMS2_k127_5248655_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1022.0
CMS2_k127_5248655_20 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 401.0
CMS2_k127_5248655_21 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 383.0
CMS2_k127_5248655_22 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 321.0
CMS2_k127_5248655_23 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 327.0
CMS2_k127_5248655_24 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 308.0
CMS2_k127_5248655_25 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 318.0
CMS2_k127_5248655_26 lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 325.0
CMS2_k127_5248655_27 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000345 283.0
CMS2_k127_5248655_28 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008194 279.0
CMS2_k127_5248655_29 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000006857 278.0
CMS2_k127_5248655_3 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 1.047e-263 824.0
CMS2_k127_5248655_30 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002506 259.0
CMS2_k127_5248655_31 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000085 269.0
CMS2_k127_5248655_32 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001344 274.0
CMS2_k127_5248655_33 tRNA synthetases class II (A) K07050 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000001086 261.0
CMS2_k127_5248655_34 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000001107 253.0
CMS2_k127_5248655_35 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003333 250.0
CMS2_k127_5248655_36 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000005789 250.0
CMS2_k127_5248655_37 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000003245 251.0
CMS2_k127_5248655_38 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000001242 239.0
CMS2_k127_5248655_39 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000194 212.0
CMS2_k127_5248655_4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.994e-245 775.0
CMS2_k127_5248655_40 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.000000000000000000000000000000000000000000000000000000003359 218.0
CMS2_k127_5248655_41 endoribonuclease - - - 0.00000000000000000000000000000000000000000000000009412 180.0
CMS2_k127_5248655_42 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000002601 181.0
CMS2_k127_5248655_43 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000000000007151 177.0
CMS2_k127_5248655_44 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000009184 177.0
CMS2_k127_5248655_45 Ribosomal protein L31 K02909 - - 0.000000000000000000000000000000000000000005977 156.0
CMS2_k127_5248655_46 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000004919 155.0
CMS2_k127_5248655_47 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.0000000000000000000000000000000001682 140.0
CMS2_k127_5248655_48 PFAM Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000002268 132.0
CMS2_k127_5248655_49 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000007968 128.0
CMS2_k127_5248655_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.511e-236 735.0
CMS2_k127_5248655_50 CRS1_YhbY K07574 - - 0.000000000000000000000002581 111.0
CMS2_k127_5248655_51 MarR family - - - 0.0000000000000003757 84.0
CMS2_k127_5248655_52 TM2 domain - - - 0.000000000001581 73.0
CMS2_k127_5248655_54 Flagellar protein FliT K02423 - - 0.00003364 50.0
CMS2_k127_5248655_55 - - - - 0.0002294 44.0
CMS2_k127_5248655_6 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 9.866e-205 645.0
CMS2_k127_5248655_7 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 6.712e-200 644.0
CMS2_k127_5248655_8 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 589.0
CMS2_k127_5248655_9 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 558.0
CMS2_k127_5251895_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.97e-293 908.0
CMS2_k127_5251895_1 PFAM AMP-dependent synthetase and ligase - - - 1.699e-231 726.0
CMS2_k127_5251895_10 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 370.0
CMS2_k127_5251895_11 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 364.0
CMS2_k127_5251895_12 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 291.0
CMS2_k127_5251895_13 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002507 279.0
CMS2_k127_5251895_14 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000824 243.0
CMS2_k127_5251895_15 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000049 201.0
CMS2_k127_5251895_16 Cytochrome c K08738 - - 0.0000000000000000000000000000002258 126.0
CMS2_k127_5251895_18 Protein of unknown function (DUF3617) - - - 0.000000000001581 76.0
CMS2_k127_5251895_19 - - - - 0.0003248 47.0
CMS2_k127_5251895_2 AMP-binding enzyme C-terminal domain K18661 - - 6.896e-230 726.0
CMS2_k127_5251895_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 482.0
CMS2_k127_5251895_4 oxidoreductase FAD NAD(P)-binding domain protein K00523,K18248 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 479.0
CMS2_k127_5251895_5 PFAM Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 457.0
CMS2_k127_5251895_6 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 456.0
CMS2_k127_5251895_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 416.0
CMS2_k127_5251895_8 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 413.0
CMS2_k127_5251895_9 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 385.0
CMS2_k127_5283759_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 4.955e-257 804.0
CMS2_k127_5283759_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.202e-239 761.0
CMS2_k127_5283759_10 NAD(FAD)-dependent dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 377.0
CMS2_k127_5283759_11 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 349.0
CMS2_k127_5283759_12 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 329.0
CMS2_k127_5283759_13 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 334.0
CMS2_k127_5283759_14 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 329.0
CMS2_k127_5283759_15 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 307.0
CMS2_k127_5283759_16 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001845 243.0
CMS2_k127_5283759_17 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000003191 215.0
CMS2_k127_5283759_18 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000005571 201.0
CMS2_k127_5283759_19 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000162 186.0
CMS2_k127_5283759_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.833e-213 681.0
CMS2_k127_5283759_20 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000001314 181.0
CMS2_k127_5283759_21 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000002842 168.0
CMS2_k127_5283759_22 - - - - 0.000000000000000000000000000000000000001506 156.0
CMS2_k127_5283759_23 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000009164 142.0
CMS2_k127_5283759_24 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000002796 138.0
CMS2_k127_5283759_25 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000002062 126.0
CMS2_k127_5283759_26 AntiSigma factor - - - 0.0000000000000000000000002145 120.0
CMS2_k127_5283759_27 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000103 96.0
CMS2_k127_5283759_28 - - - - 0.0000001475 63.0
CMS2_k127_5283759_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 543.0
CMS2_k127_5283759_4 Domain of unknown function (DUF3482) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 562.0
CMS2_k127_5283759_5 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 520.0
CMS2_k127_5283759_6 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 503.0
CMS2_k127_5283759_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 495.0
CMS2_k127_5283759_8 PFAM Mandelate racemase muconate lactonizing K01856,K02549 - 4.2.1.113,5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 484.0
CMS2_k127_5283759_9 demethylmenaquinone methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 376.0
CMS2_k127_5403484_0 Dehydrogenase K00252 - 1.3.8.6 2.119e-230 722.0
CMS2_k127_5403484_1 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 533.0
CMS2_k127_5403484_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000008494 244.0
CMS2_k127_5403484_11 TPM domain - - - 0.00000000000000000000000000000000000000000000000000000000006076 218.0
CMS2_k127_5403484_12 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000005778 177.0
CMS2_k127_5403484_13 Pfam:TPM - - - 0.000000000000000000000000000000000000000002987 160.0
CMS2_k127_5403484_14 Sel1-like repeats. K07126 - - 0.000000000000000163 90.0
CMS2_k127_5403484_15 Protein of unknown function (DUF3108) - - - 0.000000000000002945 90.0
CMS2_k127_5403484_2 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 513.0
CMS2_k127_5403484_3 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 421.0
CMS2_k127_5403484_4 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 363.0
CMS2_k127_5403484_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 321.0
CMS2_k127_5403484_6 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 320.0
CMS2_k127_5403484_7 Amino acid synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 304.0
CMS2_k127_5403484_8 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001584 277.0
CMS2_k127_5403484_9 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001129 271.0
CMS2_k127_5408468_0 Histidine kinase K02487,K06596 - - 0.0 1215.0
CMS2_k127_5408468_1 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 578.0
CMS2_k127_5408468_10 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 344.0
CMS2_k127_5408468_11 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 334.0
CMS2_k127_5408468_12 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 317.0
CMS2_k127_5408468_13 Male sterility protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 309.0
CMS2_k127_5408468_14 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 306.0
CMS2_k127_5408468_15 Transport permease protein K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001345 259.0
CMS2_k127_5408468_16 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000001996 239.0
CMS2_k127_5408468_17 Glycosyl transferase, family 2 K12990 - - 0.0000000000000000000000000000000000000000000000000000000000000000007807 259.0
CMS2_k127_5408468_18 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000000001351 215.0
CMS2_k127_5408468_19 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000008761 226.0
CMS2_k127_5408468_2 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 577.0
CMS2_k127_5408468_20 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000001018 220.0
CMS2_k127_5408468_21 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000000000000000000000000000000000000000129 190.0
CMS2_k127_5408468_22 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000000000000001768 207.0
CMS2_k127_5408468_23 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000000000000000000000000000000000000000000001854 187.0
CMS2_k127_5408468_24 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000000000009272 183.0
CMS2_k127_5408468_25 PFAM phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000005285 174.0
CMS2_k127_5408468_26 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000222 148.0
CMS2_k127_5408468_27 Chemotaxis signal transduction protein K02659 - - 0.00000000000000000000000000000001196 139.0
CMS2_k127_5408468_28 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000006474 122.0
CMS2_k127_5408468_29 Glycosyl transferases group 1 - - - 0.000002884 50.0
CMS2_k127_5408468_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 555.0
CMS2_k127_5408468_4 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 526.0
CMS2_k127_5408468_5 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 518.0
CMS2_k127_5408468_6 glycosyl transferase family 8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 498.0
CMS2_k127_5408468_7 ABC transporter K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 479.0
CMS2_k127_5408468_8 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 445.0
CMS2_k127_5408468_9 CHASE2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 413.0
CMS2_k127_5517457_0 Recombination factor protein RarA K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 627.0
CMS2_k127_5517457_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 398.0
CMS2_k127_5517457_2 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000002823 194.0
CMS2_k127_5519525_0 D-aminoacylase domain protein K06015 - 3.5.1.81 2.875e-259 805.0
CMS2_k127_5519525_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.125e-248 779.0
CMS2_k127_5519525_10 acid transport system permease K09970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 397.0
CMS2_k127_5519525_11 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 370.0
CMS2_k127_5519525_12 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 365.0
CMS2_k127_5519525_13 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 328.0
CMS2_k127_5519525_14 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 325.0
CMS2_k127_5519525_15 YCII-related domain K09780 - - 0.000000000000000000000004776 106.0
CMS2_k127_5519525_16 - - - - 0.00000000000001752 87.0
CMS2_k127_5519525_17 Type II secretion system protein B K02451 - - 0.00000002656 59.0
CMS2_k127_5519525_2 fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 589.0
CMS2_k127_5519525_3 Type II secretory pathway, component ExeA K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 571.0
CMS2_k127_5519525_4 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 547.0
CMS2_k127_5519525_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 527.0
CMS2_k127_5519525_6 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 527.0
CMS2_k127_5519525_7 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 519.0
CMS2_k127_5519525_8 Belongs to the DapA family K01714,K13876 - 4.2.1.43,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 493.0
CMS2_k127_5519525_9 ABC transporter K02028,K09972 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 442.0
CMS2_k127_552956_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 578.0
CMS2_k127_552956_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001249 272.0
CMS2_k127_559876_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1409.0
CMS2_k127_559876_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 9.552e-304 939.0
CMS2_k127_559876_10 histidine kinase HAMP region domain protein K07638 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 363.0
CMS2_k127_559876_11 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 289.0
CMS2_k127_559876_12 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 288.0
CMS2_k127_559876_13 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 285.0
CMS2_k127_559876_14 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003651 245.0
CMS2_k127_559876_15 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000001658 251.0
CMS2_k127_559876_16 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000001521 237.0
CMS2_k127_559876_17 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000343 229.0
CMS2_k127_559876_18 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000009066 194.0
CMS2_k127_559876_19 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000003218 99.0
CMS2_k127_559876_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 8.273e-248 781.0
CMS2_k127_559876_20 O-methyltransferase, family 2 - - - 0.0000001424 58.0
CMS2_k127_559876_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.869e-213 674.0
CMS2_k127_559876_4 Cysteine-rich domain - - - 1.55e-202 641.0
CMS2_k127_559876_5 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 496.0
CMS2_k127_559876_6 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 398.0
CMS2_k127_559876_7 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 383.0
CMS2_k127_559876_8 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 380.0
CMS2_k127_559876_9 response regulator K02483,K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 355.0
CMS2_k127_5617115_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1280.0
CMS2_k127_5617115_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1123.0
CMS2_k127_5617115_10 PFAM extracellular solute-binding protein family 1 K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 567.0
CMS2_k127_5617115_11 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 523.0
CMS2_k127_5617115_12 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 512.0
CMS2_k127_5617115_13 Histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 509.0
CMS2_k127_5617115_14 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 518.0
CMS2_k127_5617115_15 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 509.0
CMS2_k127_5617115_16 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 438.0
CMS2_k127_5617115_17 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 424.0
CMS2_k127_5617115_18 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 452.0
CMS2_k127_5617115_19 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 430.0
CMS2_k127_5617115_2 AcrB/AcrD/AcrF family - - - 2.995e-309 998.0
CMS2_k127_5617115_20 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 389.0
CMS2_k127_5617115_21 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 403.0
CMS2_k127_5617115_22 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 387.0
CMS2_k127_5617115_23 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 387.0
CMS2_k127_5617115_24 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 381.0
CMS2_k127_5617115_25 impB/mucB/samB family K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 384.0
CMS2_k127_5617115_26 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 369.0
CMS2_k127_5617115_27 TRAP transporter solute receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 373.0
CMS2_k127_5617115_28 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 373.0
CMS2_k127_5617115_29 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 370.0
CMS2_k127_5617115_3 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.861e-291 902.0
CMS2_k127_5617115_30 Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 380.0
CMS2_k127_5617115_31 Protein of unknown function (DUF3422) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 349.0
CMS2_k127_5617115_32 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 320.0
CMS2_k127_5617115_33 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 324.0
CMS2_k127_5617115_34 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009612 313.0
CMS2_k127_5617115_35 peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 305.0
CMS2_k127_5617115_36 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 305.0
CMS2_k127_5617115_37 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 285.0
CMS2_k127_5617115_38 KR domain K00059,K18337 - 1.1.1.100,1.1.1.173,1.1.1.377,1.1.1.378 0.000000000000000000000000000000000000000000000000000000000000000000000000000000175 274.0
CMS2_k127_5617115_39 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001496 271.0
CMS2_k127_5617115_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 2.019e-283 878.0
CMS2_k127_5617115_40 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009535 249.0
CMS2_k127_5617115_41 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003658 255.0
CMS2_k127_5617115_42 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000001309 251.0
CMS2_k127_5617115_43 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000004601 247.0
CMS2_k127_5617115_44 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007808 241.0
CMS2_k127_5617115_45 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002159 239.0
CMS2_k127_5617115_46 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000001715 236.0
CMS2_k127_5617115_47 - - - - 0.00000000000000000000000000000000000000000000000000000000000002417 220.0
CMS2_k127_5617115_48 DSBA-like thioredoxin domain K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000000000000000000003272 214.0
CMS2_k127_5617115_49 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000003882 219.0
CMS2_k127_5617115_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 6.147e-236 734.0
CMS2_k127_5617115_50 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000000000000000000000001722 210.0
CMS2_k127_5617115_51 GnaT family - - - 0.000000000000000000000000000000000000000000000000000000002448 213.0
CMS2_k127_5617115_52 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000002311 202.0
CMS2_k127_5617115_53 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.000000000000000000000000000000000000000000000000000001215 200.0
CMS2_k127_5617115_54 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000008286 205.0
CMS2_k127_5617115_55 Lactoylglutathione lyase - - - 0.000000000000000000000000000000000000000000000000005039 193.0
CMS2_k127_5617115_56 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000003762 181.0
CMS2_k127_5617115_57 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000001844 177.0
CMS2_k127_5617115_58 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000003038 177.0
CMS2_k127_5617115_59 OsmC-like protein - - - 0.00000000000000000000000000000000000000000005152 168.0
CMS2_k127_5617115_6 Na+/Pi-cotransporter K03324 - - 2.259e-217 717.0
CMS2_k127_5617115_60 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000000000000000000000000002574 164.0
CMS2_k127_5617115_61 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000001757 163.0
CMS2_k127_5617115_62 SnoaL-like domain - - - 0.000000000000000000000000000000000001629 143.0
CMS2_k127_5617115_63 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000001774 151.0
CMS2_k127_5617115_64 Protein of unknown function (DUF2846) - - - 0.000000000000000000000000000000002019 136.0
CMS2_k127_5617115_65 - - - - 0.0000000000000000000000000000000037 141.0
CMS2_k127_5617115_66 TfoX N-terminal domain - - - 0.00000000000000000000000000000003834 138.0
CMS2_k127_5617115_67 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000133 119.0
CMS2_k127_5617115_68 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000000543 123.0
CMS2_k127_5617115_69 Peptidase family M23 - - - 0.000000000000000000000000002947 121.0
CMS2_k127_5617115_7 transport system, fused permease components - - - 2.598e-217 691.0
CMS2_k127_5617115_70 - - - - 0.000000000000000000002309 98.0
CMS2_k127_5617115_71 Universal stress protein - - - 0.00000000000000000003627 96.0
CMS2_k127_5617115_72 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000002298 96.0
CMS2_k127_5617115_73 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000002268 81.0
CMS2_k127_5617115_74 Histidine kinase K07675 - 2.7.13.3 0.000000002165 68.0
CMS2_k127_5617115_8 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 5.23e-207 656.0
CMS2_k127_5617115_9 binding-protein-dependent transport systems inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 584.0
CMS2_k127_5666318_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1133.0
CMS2_k127_5666318_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.014e-286 888.0
CMS2_k127_5666318_10 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 376.0
CMS2_k127_5666318_11 Transcriptional regulatory protein, C terminal K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 339.0
CMS2_k127_5666318_12 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 363.0
CMS2_k127_5666318_13 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 317.0
CMS2_k127_5666318_14 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001707 287.0
CMS2_k127_5666318_15 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000339 220.0
CMS2_k127_5666318_16 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000004122 211.0
CMS2_k127_5666318_17 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000000009012 175.0
CMS2_k127_5666318_18 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.0000000000000000000000000000000000000000000008297 181.0
CMS2_k127_5666318_19 Universal stress protein - - - 0.000000000000000000000000000008234 129.0
CMS2_k127_5666318_2 Ammonium Transporter Family K03320,K06580 - - 4.93e-197 626.0
CMS2_k127_5666318_20 -O-antigen - - - 0.0004899 49.0
CMS2_k127_5666318_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 643.0
CMS2_k127_5666318_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 550.0
CMS2_k127_5666318_5 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 541.0
CMS2_k127_5666318_6 HemN C-terminal domain - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 499.0
CMS2_k127_5666318_7 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 462.0
CMS2_k127_5666318_8 Histidine kinase K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 462.0
CMS2_k127_5666318_9 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 395.0
CMS2_k127_5890837_0 aminopeptidase N K01256 - 3.4.11.2 9.8e-322 1017.0
CMS2_k127_5890837_1 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain III, Phosphoglucomutase phosphomannomutase, C-terminal domain, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 1.662e-204 645.0
CMS2_k127_5890837_10 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 323.0
CMS2_k127_5890837_11 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000002098 248.0
CMS2_k127_5890837_12 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000001087 225.0
CMS2_k127_5890837_13 - - - - 0.00000000000000000000000000000000000000000000000000000001041 200.0
CMS2_k127_5890837_14 HlyD membrane-fusion protein of T1SS K12537,K16300 - - 0.000000000000000000000000007291 110.0
CMS2_k127_5890837_15 Outer membrane efflux protein K12538 - - 0.000000000000000000000001405 118.0
CMS2_k127_5890837_2 Kef-type K transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 561.0
CMS2_k127_5890837_3 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 525.0
CMS2_k127_5890837_4 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 432.0
CMS2_k127_5890837_5 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 428.0
CMS2_k127_5890837_6 Convertase P-domain protein K20755 - 3.4.21.121 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 374.0
CMS2_k127_5890837_7 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 370.0
CMS2_k127_5890837_8 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 375.0
CMS2_k127_5890837_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 368.0
CMS2_k127_5914841_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1134.0
CMS2_k127_5914841_1 GTP-binding protein K06207 - - 1.936e-313 989.0
CMS2_k127_5914841_10 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 316.0
CMS2_k127_5914841_11 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000003136 267.0
CMS2_k127_5914841_12 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002272 257.0
CMS2_k127_5914841_13 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002756 259.0
CMS2_k127_5914841_14 plastoquinol--plastocyanin reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001119 254.0
CMS2_k127_5914841_15 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000009922 159.0
CMS2_k127_5914841_16 SWI complex, BAF60b domains - - - 0.00000000000000000000000000000000000003182 147.0
CMS2_k127_5914841_17 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000005639 148.0
CMS2_k127_5914841_18 PIN domain - - - 0.00000000000000000006359 96.0
CMS2_k127_5914841_19 SMART Water Stress and Hypersensitive response - - - 0.0000000001076 72.0
CMS2_k127_5914841_2 Participates in both transcription termination and antitermination K02600 - - 2.046e-238 755.0
CMS2_k127_5914841_20 - - - - 0.0000000009344 66.0
CMS2_k127_5914841_21 carboxylase carboxyl transferase subunit alpha - - - 0.000000002338 67.0
CMS2_k127_5914841_22 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0002392 48.0
CMS2_k127_5914841_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.891e-225 710.0
CMS2_k127_5914841_4 Aminotransferase K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 550.0
CMS2_k127_5914841_5 PFAM Benzoate membrane transport protein K05782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 509.0
CMS2_k127_5914841_6 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 383.0
CMS2_k127_5914841_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 385.0
CMS2_k127_5914841_8 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 371.0
CMS2_k127_5914841_9 cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 338.0
CMS2_k127_5921788_0 4Fe-4S dicluster domain - - - 0.0 1414.0
CMS2_k127_5921788_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1137.0
CMS2_k127_5921788_10 Guanyl-specific ribonuclease Sa K01167 - 3.1.27.3 0.00000000000000000000000000000002134 147.0
CMS2_k127_5921788_2 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 5.832e-200 632.0
CMS2_k127_5921788_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 554.0
CMS2_k127_5921788_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 512.0
CMS2_k127_5921788_5 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 295.0
CMS2_k127_5921788_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001132 278.0
CMS2_k127_5921788_7 Protein of unknown function (DUF1631) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001138 297.0
CMS2_k127_5921788_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000005535 201.0
CMS2_k127_5921788_9 Barstar (Barnase inhibitor) - - - 0.00000000000000000000000000000000000000007823 163.0
CMS2_k127_6011658_0 Penicillin amidase K01434 - 3.5.1.11 2.552e-290 912.0
CMS2_k127_6011658_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 2.294e-248 791.0
CMS2_k127_6011658_10 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 533.0
CMS2_k127_6011658_11 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 516.0
CMS2_k127_6011658_12 PFAM binding-protein-dependent transport systems inner membrane component K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 533.0
CMS2_k127_6011658_13 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 513.0
CMS2_k127_6011658_14 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 494.0
CMS2_k127_6011658_15 DNA recombination protein, rmuC K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 481.0
CMS2_k127_6011658_16 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 453.0
CMS2_k127_6011658_17 Membrane-bound serine protease (ClpP class) K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 452.0
CMS2_k127_6011658_18 General secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 443.0
CMS2_k127_6011658_19 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 431.0
CMS2_k127_6011658_2 type II secretion system protein E K02454 - - 1.678e-245 778.0
CMS2_k127_6011658_20 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 432.0
CMS2_k127_6011658_21 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 415.0
CMS2_k127_6011658_22 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139,K18903 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 412.0
CMS2_k127_6011658_23 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 415.0
CMS2_k127_6011658_24 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 366.0
CMS2_k127_6011658_25 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 371.0
CMS2_k127_6011658_26 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 356.0
CMS2_k127_6011658_27 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 374.0
CMS2_k127_6011658_28 Chlorophyllase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 327.0
CMS2_k127_6011658_29 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 344.0
CMS2_k127_6011658_3 ABC-type dipeptide transport system, periplasmic component K02035 - - 3.76e-226 711.0
CMS2_k127_6011658_30 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 311.0
CMS2_k127_6011658_31 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001034 284.0
CMS2_k127_6011658_32 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003625 273.0
CMS2_k127_6011658_33 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002057 255.0
CMS2_k127_6011658_34 General secretion pathway protein L K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000004222 260.0
CMS2_k127_6011658_35 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000002028 226.0
CMS2_k127_6011658_36 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000001136 240.0
CMS2_k127_6011658_37 PFAM globin K06886 - - 0.0000000000000000000000000000000000000000000000000000000000000001213 223.0
CMS2_k127_6011658_38 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000009945 229.0
CMS2_k127_6011658_39 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000007584 232.0
CMS2_k127_6011658_4 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 7.148e-221 702.0
CMS2_k127_6011658_40 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000001855 203.0
CMS2_k127_6011658_41 General Secretory Pathway K02463 - - 0.00000000000000000000000000000000000000000000000000000005264 205.0
CMS2_k127_6011658_42 COG0655 Multimeric flavodoxin WrbA - - - 0.00000000000000000000000000000000000000000000000000001048 198.0
CMS2_k127_6011658_43 - - - - 0.000000000000000000000000000000000000000000000000001171 192.0
CMS2_k127_6011658_44 general secretion pathway protein K K02460 - - 0.000000000000000000000000000000000000000000000000001996 194.0
CMS2_k127_6011658_45 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000001872 181.0
CMS2_k127_6011658_46 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.00000000000000000000000000000000000007474 166.0
CMS2_k127_6011658_47 general secretion pathway protein K02457 - - 0.0000000000000000000000000000000000006605 153.0
CMS2_k127_6011658_48 general secretion pathway protein K02459 - - 0.0000000000000000000000000000000004682 139.0
CMS2_k127_6011658_49 Major facilitator - - - 0.0000000000000000000000000000000005429 146.0
CMS2_k127_6011658_5 general secretion pathway protein D K02453 - - 8e-210 696.0
CMS2_k127_6011658_50 General secretion pathway protein I K02458 - - 0.000000000000000000000000000000007503 136.0
CMS2_k127_6011658_51 General secretion pathway K02462 - - 0.0000000000000000000002645 110.0
CMS2_k127_6011658_52 methyltransferase activity - - - 0.00000000000000001695 89.0
CMS2_k127_6011658_53 general secretion pathway protein K02452 - - 0.0000006354 60.0
CMS2_k127_6011658_54 3-hydroxyacyl-CoA dehydrogenase - - - 0.0000228 50.0
CMS2_k127_6011658_6 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 2.672e-199 652.0
CMS2_k127_6011658_7 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 612.0
CMS2_k127_6011658_8 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 570.0
CMS2_k127_6011658_9 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 564.0
CMS2_k127_6057446_0 ABC-type dipeptide transport system periplasmic component K02035 - - 1.872e-303 936.0
CMS2_k127_6057446_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.738e-248 781.0
CMS2_k127_6057446_10 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 406.0
CMS2_k127_6057446_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000005428 237.0
CMS2_k127_6057446_12 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000008709 180.0
CMS2_k127_6057446_13 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000008241 136.0
CMS2_k127_6057446_2 MlrC C-terminus - - - 1.232e-225 708.0
CMS2_k127_6057446_3 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 8.279e-204 639.0
CMS2_k127_6057446_4 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 559.0
CMS2_k127_6057446_5 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 522.0
CMS2_k127_6057446_6 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 506.0
CMS2_k127_6057446_7 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 493.0
CMS2_k127_6057446_8 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 446.0
CMS2_k127_6057446_9 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 410.0
CMS2_k127_6066530_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 5.516e-259 810.0
CMS2_k127_6066530_1 COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase Amino acid transport and metabolism Coenzyme metabolism K01652 - 2.2.1.6 1.711e-220 703.0
CMS2_k127_6066530_10 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000229 287.0
CMS2_k127_6066530_11 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000000000008756 207.0
CMS2_k127_6066530_12 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000005075 188.0
CMS2_k127_6066530_13 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000003569 166.0
CMS2_k127_6066530_14 17 kDa surface antigen K06077 - - 0.0000000000000000000004001 112.0
CMS2_k127_6066530_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 7.017e-205 649.0
CMS2_k127_6066530_3 extracellular solute-binding protein, family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 600.0
CMS2_k127_6066530_4 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 500.0
CMS2_k127_6066530_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 475.0
CMS2_k127_6066530_6 NADP-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 469.0
CMS2_k127_6066530_7 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 385.0
CMS2_k127_6066530_8 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 337.0
CMS2_k127_6066530_9 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 293.0
CMS2_k127_6090274_0 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1500.0
CMS2_k127_6090274_1 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 455.0
CMS2_k127_6090274_10 lipid kinase, YegS Rv2252 BmrU family - - - 0.00000000000000000000000000000000000006632 155.0
CMS2_k127_6090274_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 448.0
CMS2_k127_6090274_3 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 388.0
CMS2_k127_6090274_4 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 395.0
CMS2_k127_6090274_5 Predicted metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 316.0
CMS2_k127_6090274_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 291.0
CMS2_k127_6090274_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000003957 192.0
CMS2_k127_6090274_8 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000003675 188.0
CMS2_k127_6090274_9 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000003876 169.0
CMS2_k127_6114000_0 ABC-type dipeptide transport system periplasmic component K02035 - - 4.22e-253 789.0
CMS2_k127_6114000_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.641e-197 629.0
CMS2_k127_6114000_10 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 428.0
CMS2_k127_6114000_11 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 421.0
CMS2_k127_6114000_12 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 392.0
CMS2_k127_6114000_13 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 365.0
CMS2_k127_6114000_14 Glutathione S-transferase, C-terminal domain K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 355.0
CMS2_k127_6114000_15 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 365.0
CMS2_k127_6114000_16 ABC-type polar amino acid transport system ATPase component K02028,K09972 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 353.0
CMS2_k127_6114000_17 ABC-type amino acid transport system permease component K02029,K10002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 337.0
CMS2_k127_6114000_18 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 302.0
CMS2_k127_6114000_19 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 313.0
CMS2_k127_6114000_2 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 543.0
CMS2_k127_6114000_20 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 318.0
CMS2_k127_6114000_21 Major facilitator superfamily K08217 - - 0.0000000000000000000000000000000000000000000000000000000002678 218.0
CMS2_k127_6114000_22 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000444 171.0
CMS2_k127_6114000_23 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000003887 169.0
CMS2_k127_6114000_25 - - - - 0.000000000000000000000000009198 112.0
CMS2_k127_6114000_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 501.0
CMS2_k127_6114000_4 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 476.0
CMS2_k127_6114000_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 476.0
CMS2_k127_6114000_6 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 467.0
CMS2_k127_6114000_7 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 461.0
CMS2_k127_6114000_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 433.0
CMS2_k127_6114000_9 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 447.0
CMS2_k127_6145363_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1234.0
CMS2_k127_6145363_1 Male sterility protein - - - 1.675e-318 989.0
CMS2_k127_6145363_10 Threonine synthase K01733 - 4.2.3.1 2.547e-202 639.0
CMS2_k127_6145363_11 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 3.13e-201 633.0
CMS2_k127_6145363_12 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 609.0
CMS2_k127_6145363_13 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 608.0
CMS2_k127_6145363_14 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 545.0
CMS2_k127_6145363_15 NADH:flavin oxidoreductase / NADH oxidase family K00354 - 1.6.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 518.0
CMS2_k127_6145363_16 AAA domain K03582 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 504.0
CMS2_k127_6145363_17 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 453.0
CMS2_k127_6145363_18 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 367.0
CMS2_k127_6145363_19 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 338.0
CMS2_k127_6145363_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 9.017e-271 846.0
CMS2_k127_6145363_20 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 331.0
CMS2_k127_6145363_21 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 349.0
CMS2_k127_6145363_22 Amino acid synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 309.0
CMS2_k127_6145363_23 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 337.0
CMS2_k127_6145363_24 Bacterial transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002486 277.0
CMS2_k127_6145363_25 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004009 276.0
CMS2_k127_6145363_26 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000007563 282.0
CMS2_k127_6145363_27 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000000000000000000000008383 236.0
CMS2_k127_6145363_28 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001283 243.0
CMS2_k127_6145363_29 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000002316 220.0
CMS2_k127_6145363_3 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 5.908e-239 750.0
CMS2_k127_6145363_30 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000008595 216.0
CMS2_k127_6145363_31 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000001343 220.0
CMS2_k127_6145363_32 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000127 222.0
CMS2_k127_6145363_33 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000002588 202.0
CMS2_k127_6145363_34 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000005016 189.0
CMS2_k127_6145363_35 - - - - 0.00000000000000000000000000000000000000000000000000005023 196.0
CMS2_k127_6145363_36 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000009254 199.0
CMS2_k127_6145363_37 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000001362 151.0
CMS2_k127_6145363_38 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000001807 153.0
CMS2_k127_6145363_39 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000005109 157.0
CMS2_k127_6145363_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 5.638e-226 707.0
CMS2_k127_6145363_40 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000003911 152.0
CMS2_k127_6145363_41 Copper resistance protein D - - - 0.0000000000000000000000000000000001305 138.0
CMS2_k127_6145363_42 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000002942 132.0
CMS2_k127_6145363_43 PFAM poly granule associated family protein - - - 0.00000000000000000000000000000002257 135.0
CMS2_k127_6145363_44 PFAM acyl-coA-binding protein, ACBP - - - 0.000000000000000000000000000001117 140.0
CMS2_k127_6145363_45 twin-arginine translocation pathway signal protein - - - 0.000000000000000000000000005945 127.0
CMS2_k127_6145363_46 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000001045 120.0
CMS2_k127_6145363_47 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K09740 - - 0.00000000000000000008232 91.0
CMS2_k127_6145363_48 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000019 96.0
CMS2_k127_6145363_49 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000004507 85.0
CMS2_k127_6145363_5 GMC oxidoreductase - - - 1.042e-215 690.0
CMS2_k127_6145363_50 Ribosomal RNA adenine dimethylase - - - 0.0000000000000000469 89.0
CMS2_k127_6145363_51 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.0000000000000002414 92.0
CMS2_k127_6145363_6 SAF - - - 2.142e-214 673.0
CMS2_k127_6145363_7 Amidohydrolase family K15358 - 3.5.2.18 9.081e-214 669.0
CMS2_k127_6145363_8 Aminotransferase K14261 - - 4.688e-212 675.0
CMS2_k127_6145363_9 homoserine dehydrogenase K00003 - 1.1.1.3 3.594e-203 662.0
CMS2_k127_6169374_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1092.0
CMS2_k127_6169374_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.789e-250 784.0
CMS2_k127_6169374_10 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 453.0
CMS2_k127_6169374_11 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 396.0
CMS2_k127_6169374_12 KR domain K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 391.0
CMS2_k127_6169374_13 PFAM TatD-related deoxyribonuclease K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 309.0
CMS2_k127_6169374_14 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000108 295.0
CMS2_k127_6169374_15 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001127 288.0
CMS2_k127_6169374_16 Iron-sulfur cluster assembly transcription factor K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007045 258.0
CMS2_k127_6169374_17 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001556 257.0
CMS2_k127_6169374_18 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000002992 236.0
CMS2_k127_6169374_19 Low molecular weight phosphotyrosine protein phosphatase K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000001223 238.0
CMS2_k127_6169374_2 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 1.328e-249 785.0
CMS2_k127_6169374_20 Ferredoxin K04755 - - 0.000000000000000000000000000000000000000000000004314 175.0
CMS2_k127_6169374_21 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000001712 179.0
CMS2_k127_6169374_22 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.000000000000000000000000000000000000000000001163 170.0
CMS2_k127_6169374_23 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000002083 165.0
CMS2_k127_6169374_24 Iron-sulphur cluster assembly - - - 0.000000000000000000000000001433 113.0
CMS2_k127_6169374_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.976e-208 666.0
CMS2_k127_6169374_4 single-stranded-DNA-specific exonuclease RecJ K07462 - - 9.392e-203 653.0
CMS2_k127_6169374_5 PFAM aminotransferase class I and II K00832 - 2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 598.0
CMS2_k127_6169374_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 548.0
CMS2_k127_6169374_7 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 572.0
CMS2_k127_6169374_8 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 546.0
CMS2_k127_6169374_9 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 514.0
CMS2_k127_6170843_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.007e-240 764.0
CMS2_k127_6170843_1 C-terminal region of band_7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 454.0
CMS2_k127_6170843_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000001331 233.0
CMS2_k127_6170843_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000008101 234.0
CMS2_k127_6170843_4 Cyclase dehydrase - - - 0.0000000000000000000000000000000000000001278 155.0
CMS2_k127_6170843_5 Domain of unknown function (DUF4124) - - - 0.0000000000001106 80.0
CMS2_k127_6170843_6 Belongs to the UPF0125 (RnfH) family K03154,K09801 - - 0.000001276 57.0
CMS2_k127_6178652_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1467.0
CMS2_k127_6178652_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 3.152e-317 989.0
CMS2_k127_6178652_10 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 452.0
CMS2_k127_6178652_11 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 413.0
CMS2_k127_6178652_12 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 409.0
CMS2_k127_6178652_13 AAA domain K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 413.0
CMS2_k127_6178652_14 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 317.0
CMS2_k127_6178652_15 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000003257 240.0
CMS2_k127_6178652_16 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000007344 209.0
CMS2_k127_6178652_17 pyridine nucleotide-disulfide oxidoreductase family protein K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000003854 211.0
CMS2_k127_6178652_18 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000000000000000000000000002444 196.0
CMS2_k127_6178652_19 PFAM regulatory protein MerR - - - 0.000000000000000000000000000000000000000000000792 170.0
CMS2_k127_6178652_2 MmgE/PrpD family K01720 - 4.2.1.79 2.151e-282 871.0
CMS2_k127_6178652_20 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000006664 140.0
CMS2_k127_6178652_21 Signal peptide protein - - - 0.0000000000002113 77.0
CMS2_k127_6178652_22 dehydrogenase - - - 0.0000001807 55.0
CMS2_k127_6178652_3 Belongs to the aldehyde dehydrogenase family K00141 - 1.2.1.28 6.813e-273 859.0
CMS2_k127_6178652_4 domain protein K03320 - - 1.669e-234 749.0
CMS2_k127_6178652_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.061e-216 680.0
CMS2_k127_6178652_6 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 3.101e-209 662.0
CMS2_k127_6178652_7 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 591.0
CMS2_k127_6178652_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 497.0
CMS2_k127_6178652_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 478.0
CMS2_k127_6181734_0 NADH ubiquinone plastoquinone (Complex I) - - - 6e-323 999.0
CMS2_k127_6181734_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.269e-317 997.0
CMS2_k127_6181734_10 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 398.0
CMS2_k127_6181734_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 366.0
CMS2_k127_6181734_12 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 337.0
CMS2_k127_6181734_13 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 307.0
CMS2_k127_6181734_14 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 304.0
CMS2_k127_6181734_15 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 290.0
CMS2_k127_6181734_16 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009454 274.0
CMS2_k127_6181734_17 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003214 280.0
CMS2_k127_6181734_18 hydrogenase 4 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000164 265.0
CMS2_k127_6181734_19 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000006052 252.0
CMS2_k127_6181734_2 Proton-conducting membrane transporter K12141 - - 7.552e-252 784.0
CMS2_k127_6181734_20 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000001388 239.0
CMS2_k127_6181734_21 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000002842 168.0
CMS2_k127_6181734_22 biopolymer transport K03559 - - 0.0000000000000000000000000000000002655 148.0
CMS2_k127_6181734_23 - - - - 0.00000000000000000000000000000001222 136.0
CMS2_k127_6181734_24 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000005874 104.0
CMS2_k127_6181734_25 Belongs to the UPF0434 family K09791 - - 0.000000000000000000008115 94.0
CMS2_k127_6181734_26 KTSC domain - - - 0.00000000002297 71.0
CMS2_k127_6181734_27 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00007186 53.0
CMS2_k127_6181734_3 ABC transporter K15738 - - 3.362e-228 727.0
CMS2_k127_6181734_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.234e-217 681.0
CMS2_k127_6181734_5 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 6.679e-217 685.0
CMS2_k127_6181734_6 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 556.0
CMS2_k127_6181734_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 536.0
CMS2_k127_6181734_8 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 477.0
CMS2_k127_6181734_9 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 491.0
CMS2_k127_6199735_0 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 5.776e-204 653.0
CMS2_k127_6199735_1 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 305.0
CMS2_k127_6199735_2 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000001675 150.0
CMS2_k127_6201441_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.325e-239 747.0
CMS2_k127_6201441_1 Belongs to the thiolase family K00626 - 2.3.1.9 5.994e-208 653.0
CMS2_k127_6201441_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 604.0
CMS2_k127_6201441_3 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 353.0
CMS2_k127_6201441_4 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 314.0
CMS2_k127_6201441_5 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 301.0
CMS2_k127_6201441_6 Allophanate hydrolase subunit 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000008532 248.0
CMS2_k127_6201441_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000001357 232.0
CMS2_k127_6201441_8 Domain of unknown function (DUF1850) - - - 0.000000000000000004255 90.0
CMS2_k127_6201441_9 ompA family - - - 0.0000007328 61.0
CMS2_k127_6378253_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0 1602.0
CMS2_k127_6378253_1 formate dehydrogenase, alpha subunit K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1544.0
CMS2_k127_6378253_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 633.0
CMS2_k127_6378253_11 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 558.0
CMS2_k127_6378253_12 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 506.0
CMS2_k127_6378253_13 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 441.0
CMS2_k127_6378253_14 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 424.0
CMS2_k127_6378253_15 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 355.0
CMS2_k127_6378253_16 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 358.0
CMS2_k127_6378253_17 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 306.0
CMS2_k127_6378253_18 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 312.0
CMS2_k127_6378253_19 Protein of unknown function (DUF560) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003801 287.0
CMS2_k127_6378253_2 Pfam Enoyl-CoA hydratase isomerase K15513 - 4.1.2.44 3.356e-316 980.0
CMS2_k127_6378253_20 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004089 264.0
CMS2_k127_6378253_21 Pfam Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000001 195.0
CMS2_k127_6378253_22 FecR protein - - - 0.00000000000000000000000002524 121.0
CMS2_k127_6378253_23 Bacterial regulatory proteins, tetR family - - - 0.00000000000386 74.0
CMS2_k127_6378253_3 benzoyl-CoA oxygenase K15512 - 1.14.13.208 4.913e-291 900.0
CMS2_k127_6378253_4 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 1.826e-278 886.0
CMS2_k127_6378253_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 6.849e-270 838.0
CMS2_k127_6378253_6 response regulator K02481 - - 1.067e-229 734.0
CMS2_k127_6378253_7 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 8.956e-224 697.0
CMS2_k127_6378253_8 Oxidoreductase NAD-binding domain K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 1.384e-223 724.0
CMS2_k127_6378253_9 Histidine kinase K02482 - 2.7.13.3 9.873e-219 691.0
CMS2_k127_6388549_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1532.0
CMS2_k127_6388549_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1392.0
CMS2_k127_6388549_10 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 3.461e-202 635.0
CMS2_k127_6388549_11 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 6.772e-194 615.0
CMS2_k127_6388549_12 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 622.0
CMS2_k127_6388549_13 twitching motility protein K02669,K12203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 609.0
CMS2_k127_6388549_14 Type II/IV secretion system protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 594.0
CMS2_k127_6388549_15 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 595.0
CMS2_k127_6388549_16 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 575.0
CMS2_k127_6388549_17 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 575.0
CMS2_k127_6388549_18 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 562.0
CMS2_k127_6388549_19 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 542.0
CMS2_k127_6388549_2 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1200.0
CMS2_k127_6388549_20 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 541.0
CMS2_k127_6388549_21 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 525.0
CMS2_k127_6388549_22 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 509.0
CMS2_k127_6388549_23 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 504.0
CMS2_k127_6388549_24 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 520.0
CMS2_k127_6388549_25 TOBE domain K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 484.0
CMS2_k127_6388549_26 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 474.0
CMS2_k127_6388549_27 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 468.0
CMS2_k127_6388549_28 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 460.0
CMS2_k127_6388549_29 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 433.0
CMS2_k127_6388549_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.562e-299 928.0
CMS2_k127_6388549_30 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 434.0
CMS2_k127_6388549_31 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 426.0
CMS2_k127_6388549_32 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 417.0
CMS2_k127_6388549_33 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 399.0
CMS2_k127_6388549_34 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 391.0
CMS2_k127_6388549_35 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 378.0
CMS2_k127_6388549_36 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 372.0
CMS2_k127_6388549_37 Mg2 and Co2 transporter K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 372.0
CMS2_k127_6388549_38 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 389.0
CMS2_k127_6388549_39 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 351.0
CMS2_k127_6388549_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.368e-262 816.0
CMS2_k127_6388549_40 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 349.0
CMS2_k127_6388549_41 PFAM conserved K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 353.0
CMS2_k127_6388549_42 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 346.0
CMS2_k127_6388549_43 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 331.0
CMS2_k127_6388549_44 reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 307.0
CMS2_k127_6388549_45 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 309.0
CMS2_k127_6388549_46 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 305.0
CMS2_k127_6388549_47 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 287.0
CMS2_k127_6388549_48 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 288.0
CMS2_k127_6388549_49 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004682 288.0
CMS2_k127_6388549_5 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.358e-218 711.0
CMS2_k127_6388549_50 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002246 271.0
CMS2_k127_6388549_51 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007539 277.0
CMS2_k127_6388549_52 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000004185 265.0
CMS2_k127_6388549_53 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000008904 276.0
CMS2_k127_6388549_54 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001067 258.0
CMS2_k127_6388549_55 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000461 256.0
CMS2_k127_6388549_56 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000005117 267.0
CMS2_k127_6388549_57 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000647 256.0
CMS2_k127_6388549_58 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000002385 247.0
CMS2_k127_6388549_59 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000003524 257.0
CMS2_k127_6388549_6 Tripartite tricarboxylate transporter TctA family K07793 - - 2.042e-215 683.0
CMS2_k127_6388549_60 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000004777 235.0
CMS2_k127_6388549_61 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000007645 229.0
CMS2_k127_6388549_62 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0003674,GO:0003824,GO:0004462,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016151,GO:0016829,GO:0016846,GO:0019243,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042182,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046872,GO:0046914,GO:0051186,GO:0051596,GO:0061727,GO:0071704,GO:1901564,GO:1901575,GO:1901615 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000001359 219.0
CMS2_k127_6388549_63 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000001025 214.0
CMS2_k127_6388549_64 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000006827 214.0
CMS2_k127_6388549_65 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000000002756 224.0
CMS2_k127_6388549_66 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000467 220.0
CMS2_k127_6388549_67 Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000000000000001646 205.0
CMS2_k127_6388549_68 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000002177 207.0
CMS2_k127_6388549_69 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000001267 188.0
CMS2_k127_6388549_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.375e-211 676.0
CMS2_k127_6388549_70 membrane K08973 - - 0.00000000000000000000000000000000000000000000001447 193.0
CMS2_k127_6388549_71 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000002155 184.0
CMS2_k127_6388549_72 - - - - 0.0000000000000000000000000000000000000000000483 165.0
CMS2_k127_6388549_73 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000002525 161.0
CMS2_k127_6388549_74 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000004528 172.0
CMS2_k127_6388549_75 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000001042 149.0
CMS2_k127_6388549_76 Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000005837 135.0
CMS2_k127_6388549_77 TIGRFAM protein TolA K03646 - - 0.000000000000000000000000000000002072 144.0
CMS2_k127_6388549_78 FtsX-like permease family K02004 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0051704,GO:0071944 - 0.000000000000000000000000000002025 134.0
CMS2_k127_6388549_79 Acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000002551 121.0
CMS2_k127_6388549_8 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 2.559e-209 677.0
CMS2_k127_6388549_80 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000416 119.0
CMS2_k127_6388549_81 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000000000007136 111.0
CMS2_k127_6388549_82 ABC-type transport auxiliary lipoprotein component - - - 0.000000000000000000000001224 120.0
CMS2_k127_6388549_83 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000000002661 106.0
CMS2_k127_6388549_84 MerR, DNA binding K19591,K19592 - - 0.000000000000000000008984 96.0
CMS2_k127_6388549_85 - - - - 0.0000000000000001803 81.0
CMS2_k127_6388549_86 - - - - 0.000000000000007364 83.0
CMS2_k127_6388549_87 - - - - 0.0000000000000523 77.0
CMS2_k127_6388549_88 Lipopolysaccharide assembly protein A domain K08992 - - 0.0000000000002631 74.0
CMS2_k127_6388549_89 - - - - 0.0000001547 53.0
CMS2_k127_6388549_9 ABC-type sugar transport system, periplasmic component K02027 - - 6.198e-204 643.0
CMS2_k127_6388549_90 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000004514 51.0
CMS2_k127_6388549_92 FtsX-like permease family K02004 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0051704,GO:0071944 - 0.0001269 48.0
CMS2_k127_6442589_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1074.0
CMS2_k127_6442589_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1066.0
CMS2_k127_6442589_10 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 487.0
CMS2_k127_6442589_11 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 495.0
CMS2_k127_6442589_12 Belongs to the peptidase S1B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 492.0
CMS2_k127_6442589_13 Putative nucleotidyltransferase substrate binding domain K02342,K07182 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 494.0
CMS2_k127_6442589_14 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 471.0
CMS2_k127_6442589_15 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 350.0
CMS2_k127_6442589_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004086 256.0
CMS2_k127_6442589_17 UPF0114 protein - - - 0.000000000000000000000000000000000000000000000000000000000000004841 224.0
CMS2_k127_6442589_18 - - - - 0.0000000000000000000000000000000000000000000000000001282 188.0
CMS2_k127_6442589_19 NlpC/P60 family K13695,K19303 - - 0.000000000000000000000000000000000000000000000002079 181.0
CMS2_k127_6442589_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1059.0
CMS2_k127_6442589_20 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000001025 195.0
CMS2_k127_6442589_21 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000001955 174.0
CMS2_k127_6442589_22 DUF218 domain - - - 0.0000000000000000000000000000000000000009611 160.0
CMS2_k127_6442589_23 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000002246 147.0
CMS2_k127_6442589_24 ferredoxin - - - 0.0000000000000000000000000000000003669 133.0
CMS2_k127_6442589_25 Domain of unknown function (DUF4212) K14393 - - 0.00000000000000000000000000138 115.0
CMS2_k127_6442589_26 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000001458 118.0
CMS2_k127_6442589_3 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 0.0 1016.0
CMS2_k127_6442589_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 4.115e-303 949.0
CMS2_k127_6442589_5 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.286e-278 863.0
CMS2_k127_6442589_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 580.0
CMS2_k127_6442589_7 Major facilitator Superfamily K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 567.0
CMS2_k127_6442589_8 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 530.0
CMS2_k127_6442589_9 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 490.0
CMS2_k127_6488021_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 1.164e-279 883.0
CMS2_k127_6488021_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.207e-201 642.0
CMS2_k127_6488021_10 COG3653 N-acyl-D-aspartate D-glutamate deacylase K01461 - 3.5.1.82 0.0003691 48.0
CMS2_k127_6488021_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 574.0
CMS2_k127_6488021_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 565.0
CMS2_k127_6488021_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 486.0
CMS2_k127_6488021_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 457.0
CMS2_k127_6488021_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000008699 106.0
CMS2_k127_6488021_7 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000004241 94.0
CMS2_k127_6488021_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000001105 79.0
CMS2_k127_6488021_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000009179 55.0
CMS2_k127_6530935_0 AcrB/AcrD/AcrF family - - - 0.0 1334.0
CMS2_k127_6530935_1 GMP synthase C terminal domain K01951 - 6.3.5.2 6.814e-289 896.0
CMS2_k127_6530935_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000002745 231.0
CMS2_k127_6530935_11 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000004692 134.0
CMS2_k127_6530935_12 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000001484 131.0
CMS2_k127_6530935_13 PFAM Bacterial regulatory protein, arsR family K22298 - - 0.0000000000000000000000000000001634 127.0
CMS2_k127_6530935_14 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000000000884 108.0
CMS2_k127_6530935_15 Protein of unknown function (DUF2892) - - - 0.00000000000000000000003473 100.0
CMS2_k127_6530935_16 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000005891 77.0
CMS2_k127_6530935_17 - - - - 0.000000001938 59.0
CMS2_k127_6530935_2 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 1.028e-266 830.0
CMS2_k127_6530935_3 Gamma-glutamyltranspeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 591.0
CMS2_k127_6530935_4 Belongs to the UPF0061 (SELO) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 584.0
CMS2_k127_6530935_5 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 452.0
CMS2_k127_6530935_6 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 325.0
CMS2_k127_6530935_7 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 287.0
CMS2_k127_6530935_8 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000007528 227.0
CMS2_k127_6530935_9 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000002947 223.0
CMS2_k127_6546946_0 Atp-dependent helicase K03578 - 3.6.4.13 0.0 1424.0
CMS2_k127_6546946_1 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1270.0
CMS2_k127_6546946_10 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 400.0
CMS2_k127_6546946_11 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 357.0
CMS2_k127_6546946_12 Fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 373.0
CMS2_k127_6546946_13 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 339.0
CMS2_k127_6546946_14 Nitrile hydratase K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 326.0
CMS2_k127_6546946_15 deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 315.0
CMS2_k127_6546946_16 PFAM molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 304.0
CMS2_k127_6546946_17 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 308.0
CMS2_k127_6546946_18 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001684 267.0
CMS2_k127_6546946_19 ornithine cyclodeaminase mu-crystallin K01750,K19743 - 1.5.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000007776 275.0
CMS2_k127_6546946_2 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 2.249e-216 683.0
CMS2_k127_6546946_20 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002102 248.0
CMS2_k127_6546946_21 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000345 251.0
CMS2_k127_6546946_22 of the double-stranded beta helix - - - 0.00000000000000000000000000000000000000000000000000000000000000001085 234.0
CMS2_k127_6546946_23 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000003358 164.0
CMS2_k127_6546946_24 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000000000000000004445 176.0
CMS2_k127_6546946_25 Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000004606 178.0
CMS2_k127_6546946_26 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000000444 163.0
CMS2_k127_6546946_27 Nitrile hydratase beta subunit - - - 0.0000000000000000000000000000000001069 147.0
CMS2_k127_6546946_28 TIGRFAM phasin family protein - - - 0.00000000000000000000000008702 114.0
CMS2_k127_6546946_3 Protein of unknown function (DUF4080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 590.0
CMS2_k127_6546946_4 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 608.0
CMS2_k127_6546946_5 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 564.0
CMS2_k127_6546946_6 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 483.0
CMS2_k127_6546946_7 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 434.0
CMS2_k127_6546946_8 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 428.0
CMS2_k127_6546946_9 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 400.0
CMS2_k127_6705926_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.059e-295 914.0
CMS2_k127_6705926_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 4.197e-236 747.0
CMS2_k127_6705926_10 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 573.0
CMS2_k127_6705926_100 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000007182 114.0
CMS2_k127_6705926_101 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000002073 116.0
CMS2_k127_6705926_102 Cytochrome oxidase assembly K02259 - - 0.00000000000000000000000005862 119.0
CMS2_k127_6705926_103 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000001702 120.0
CMS2_k127_6705926_104 Bacterial SH3 domain - - - 0.0000000000000000000000002572 117.0
CMS2_k127_6705926_105 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000003259 101.0
CMS2_k127_6705926_106 Protein of unknown function (DUF2909) - - - 0.00000000000000000001659 93.0
CMS2_k127_6705926_107 Cysteine-rich CWC - - - 0.0000000001461 66.0
CMS2_k127_6705926_108 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 - 0.000000004871 67.0
CMS2_k127_6705926_109 Protein of unknown function (DUF2970) - - - 0.00002543 55.0
CMS2_k127_6705926_11 Belongs to the GPAT DAPAT family K00631 GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 573.0
CMS2_k127_6705926_12 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 508.0
CMS2_k127_6705926_13 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 503.0
CMS2_k127_6705926_14 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 498.0
CMS2_k127_6705926_15 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 505.0
CMS2_k127_6705926_16 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 517.0
CMS2_k127_6705926_17 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 490.0
CMS2_k127_6705926_18 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 478.0
CMS2_k127_6705926_19 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 472.0
CMS2_k127_6705926_2 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 2.373e-220 693.0
CMS2_k127_6705926_20 Domain of unknown function (DUF3391) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 473.0
CMS2_k127_6705926_21 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 458.0
CMS2_k127_6705926_22 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 453.0
CMS2_k127_6705926_23 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 430.0
CMS2_k127_6705926_24 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 419.0
CMS2_k127_6705926_25 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006015 422.0
CMS2_k127_6705926_26 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 443.0
CMS2_k127_6705926_27 Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5- (5- phosphoribosylamino)methylideneamino imidazole-4-carboxamide K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 409.0
CMS2_k127_6705926_28 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 416.0
CMS2_k127_6705926_29 RNA polymerase sigma factor RpoH K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 404.0
CMS2_k127_6705926_3 Dynamin family - - - 2.472e-211 676.0
CMS2_k127_6705926_30 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 392.0
CMS2_k127_6705926_31 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 432.0
CMS2_k127_6705926_32 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 397.0
CMS2_k127_6705926_33 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 379.0
CMS2_k127_6705926_34 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 377.0
CMS2_k127_6705926_35 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 373.0
CMS2_k127_6705926_36 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 376.0
CMS2_k127_6705926_37 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 372.0
CMS2_k127_6705926_38 NUDIX domain K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 381.0
CMS2_k127_6705926_39 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 365.0
CMS2_k127_6705926_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.387e-206 662.0
CMS2_k127_6705926_40 abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 352.0
CMS2_k127_6705926_41 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 350.0
CMS2_k127_6705926_42 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 352.0
CMS2_k127_6705926_43 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 347.0
CMS2_k127_6705926_44 Domain of unknown function (DUF3391) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 348.0
CMS2_k127_6705926_45 ABC transporter permease K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 352.0
CMS2_k127_6705926_46 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 329.0
CMS2_k127_6705926_47 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 323.0
CMS2_k127_6705926_48 Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 348.0
CMS2_k127_6705926_49 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 323.0
CMS2_k127_6705926_5 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 8.962e-202 637.0
CMS2_k127_6705926_50 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 313.0
CMS2_k127_6705926_51 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 321.0
CMS2_k127_6705926_52 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 304.0
CMS2_k127_6705926_53 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 301.0
CMS2_k127_6705926_54 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 296.0
CMS2_k127_6705926_55 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 301.0
CMS2_k127_6705926_56 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 303.0
CMS2_k127_6705926_57 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 301.0
CMS2_k127_6705926_58 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002513 274.0
CMS2_k127_6705926_59 PFAM regulatory protein TetR K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002141 259.0
CMS2_k127_6705926_6 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 607.0
CMS2_k127_6705926_60 maleylacetoacetate isomerase K01801 - 5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000001011 249.0
CMS2_k127_6705926_61 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001246 254.0
CMS2_k127_6705926_62 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000278 245.0
CMS2_k127_6705926_63 toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000005691 239.0
CMS2_k127_6705926_64 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000002735 233.0
CMS2_k127_6705926_65 cytochrome C oxidase K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000003879 233.0
CMS2_k127_6705926_66 VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000007477 240.0
CMS2_k127_6705926_67 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000001917 231.0
CMS2_k127_6705926_68 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000002538 222.0
CMS2_k127_6705926_69 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000006838 229.0
CMS2_k127_6705926_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 614.0
CMS2_k127_6705926_70 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000004573 216.0
CMS2_k127_6705926_71 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000521 213.0
CMS2_k127_6705926_72 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000001388 220.0
CMS2_k127_6705926_73 response to antibiotic - - - 0.000000000000000000000000000000000000000000000000000000001527 217.0
CMS2_k127_6705926_74 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000000000005758 203.0
CMS2_k127_6705926_75 phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000002274 217.0
CMS2_k127_6705926_76 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000000000000000001787 199.0
CMS2_k127_6705926_77 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000002245 191.0
CMS2_k127_6705926_78 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000001115 192.0
CMS2_k127_6705926_79 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000001767 200.0
CMS2_k127_6705926_8 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 590.0
CMS2_k127_6705926_80 signal sequence binding - - - 0.000000000000000000000000000000000000000000000001479 185.0
CMS2_k127_6705926_81 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000004572 191.0
CMS2_k127_6705926_82 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000000000000001732 180.0
CMS2_k127_6705926_83 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000001437 175.0
CMS2_k127_6705926_84 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000000000000000000000001811 169.0
CMS2_k127_6705926_85 SURF1 family - - - 0.0000000000000000000000000000000000000000001991 169.0
CMS2_k127_6705926_86 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000001115 176.0
CMS2_k127_6705926_87 Redoxin - - - 0.000000000000000000000000000000000000000001524 180.0
CMS2_k127_6705926_88 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000002744 160.0
CMS2_k127_6705926_89 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000003043 162.0
CMS2_k127_6705926_9 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 588.0
CMS2_k127_6705926_90 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000000000000000002564 156.0
CMS2_k127_6705926_91 sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000000001092 144.0
CMS2_k127_6705926_92 stringent starvation protein b K03600 - - 0.0000000000000000000000000000000000002057 149.0
CMS2_k127_6705926_93 transcriptional regulator - - - 0.0000000000000000000000000000000000002531 153.0
CMS2_k127_6705926_94 Competence protein - - - 0.00000000000000000000000000000000000851 146.0
CMS2_k127_6705926_95 4Fe-4S binding domain - - - 0.00000000000000000000000000000000003151 150.0
CMS2_k127_6705926_96 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000002684 136.0
CMS2_k127_6705926_97 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000004556 130.0
CMS2_k127_6705926_98 Diguanylate cyclase - - - 0.0000000000000000000000000000001467 142.0
CMS2_k127_6705926_99 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.00000000000000000000000000005574 121.0
CMS2_k127_6718111_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1677.0
CMS2_k127_6718111_1 Phosphate acetyl butaryl transferase K00029 - 1.1.1.40 0.0 1144.0
CMS2_k127_6718111_10 Aldehyde dehydrogenase family - - - 2.637e-217 681.0
CMS2_k127_6718111_11 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 1.174e-195 629.0
CMS2_k127_6718111_12 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 601.0
CMS2_k127_6718111_13 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 593.0
CMS2_k127_6718111_14 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 601.0
CMS2_k127_6718111_15 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 599.0
CMS2_k127_6718111_16 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 539.0
CMS2_k127_6718111_17 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 553.0
CMS2_k127_6718111_18 Dehydrogenase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 483.0
CMS2_k127_6718111_19 C4-dicarboxylate ABC transporter substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 479.0
CMS2_k127_6718111_2 FAD dependent oxidoreductase - - - 0.0 1073.0
CMS2_k127_6718111_20 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 456.0
CMS2_k127_6718111_21 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 441.0
CMS2_k127_6718111_22 xylanase chitin deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 422.0
CMS2_k127_6718111_23 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 428.0
CMS2_k127_6718111_24 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 408.0
CMS2_k127_6718111_25 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 431.0
CMS2_k127_6718111_26 aldo keto reductase K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 366.0
CMS2_k127_6718111_27 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 310.0
CMS2_k127_6718111_28 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 293.0
CMS2_k127_6718111_29 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 281.0
CMS2_k127_6718111_3 Belongs to the IlvD Edd family K01687,K13875 - 4.2.1.25,4.2.1.9 1.225e-276 872.0
CMS2_k127_6718111_30 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 310.0
CMS2_k127_6718111_31 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001177 273.0
CMS2_k127_6718111_32 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001744 253.0
CMS2_k127_6718111_33 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004706 246.0
CMS2_k127_6718111_34 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000001879 238.0
CMS2_k127_6718111_35 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000002384 229.0
CMS2_k127_6718111_36 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000003214 221.0
CMS2_k127_6718111_37 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000001855 213.0
CMS2_k127_6718111_38 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000002079 203.0
CMS2_k127_6718111_39 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000007518 159.0
CMS2_k127_6718111_4 binding-protein-dependent transport systems inner membrane component K02011 - - 3.031e-258 826.0
CMS2_k127_6718111_40 Plasmid replication region DNA-binding N-term - - - 0.000000000000000000000000000000000000009821 154.0
CMS2_k127_6718111_41 COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.0000000000000001123 87.0
CMS2_k127_6718111_5 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 1.946e-246 771.0
CMS2_k127_6718111_6 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 4.976e-246 765.0
CMS2_k127_6718111_7 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.58e-234 732.0
CMS2_k127_6718111_8 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.498e-222 705.0
CMS2_k127_6718111_9 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 5.449e-218 684.0
CMS2_k127_6789284_0 2Fe-2S iron-sulfur cluster binding domain K03863 - - 0.0 1415.0
CMS2_k127_6789284_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.842e-256 806.0
CMS2_k127_6789284_2 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 323.0
CMS2_k127_6789284_3 Periplasmic or secreted lipoprotein K04065 - - 0.00000000000000000000000002966 111.0
CMS2_k127_6789284_4 Mut7-C RNAse domain K09122 - - 0.00000000562 68.0
CMS2_k127_6934314_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1191.0
CMS2_k127_6934314_1 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.0 1141.0
CMS2_k127_6934314_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008563 268.0
CMS2_k127_6934314_11 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000001965 219.0
CMS2_k127_6934314_12 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000004722 51.0
CMS2_k127_6934314_13 Belongs to the 'phage' integrase family - - - 0.0006317 43.0
CMS2_k127_6934314_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.874e-228 723.0
CMS2_k127_6934314_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 615.0
CMS2_k127_6934314_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 604.0
CMS2_k127_6934314_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 532.0
CMS2_k127_6934314_6 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 480.0
CMS2_k127_6934314_7 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 388.0
CMS2_k127_6934314_8 KR domain K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 358.0
CMS2_k127_6934314_9 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 302.0
CMS2_k127_6989153_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 5.988e-213 668.0
CMS2_k127_6989153_1 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00001336 48.0
CMS2_k127_73473_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.343e-302 949.0
CMS2_k127_73473_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 4.337e-263 822.0
CMS2_k127_73473_10 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 479.0
CMS2_k127_73473_11 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 459.0
CMS2_k127_73473_12 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 447.0
CMS2_k127_73473_13 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 437.0
CMS2_k127_73473_14 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 439.0
CMS2_k127_73473_15 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 401.0
CMS2_k127_73473_16 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 434.0
CMS2_k127_73473_17 3'-5' exonuclease K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 385.0
CMS2_k127_73473_18 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 368.0
CMS2_k127_73473_19 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 342.0
CMS2_k127_73473_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.244e-246 796.0
CMS2_k127_73473_20 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 334.0
CMS2_k127_73473_21 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 324.0
CMS2_k127_73473_22 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001047 279.0
CMS2_k127_73473_23 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008582 281.0
CMS2_k127_73473_24 chemotaxis, protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008024 284.0
CMS2_k127_73473_25 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000008565 241.0
CMS2_k127_73473_26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000001771 239.0
CMS2_k127_73473_27 Type IV pilus biogenesis K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000003119 254.0
CMS2_k127_73473_28 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001111 233.0
CMS2_k127_73473_29 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000001132 209.0
CMS2_k127_73473_3 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.079e-217 681.0
CMS2_k127_73473_30 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000008403 199.0
CMS2_k127_73473_31 UPF0761 membrane protein K07058 - - 0.000000000000000000000000000000000000000000000000002051 201.0
CMS2_k127_73473_32 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000000000000003005 167.0
CMS2_k127_73473_33 COG0739 Membrane proteins related to metalloendopeptidases K06194 - - 0.00000000000000000000000000000000000000000002862 180.0
CMS2_k127_73473_34 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000001286 141.0
CMS2_k127_73473_35 Predicted membrane protein (DUF2069) - - - 0.0000000000000000000001699 105.0
CMS2_k127_73473_36 Staphylococcal nuclease homologues - - - 0.000000000000000000001379 110.0
CMS2_k127_73473_37 cheY-homologous receiver domain - - - 0.000000000000000000005194 105.0
CMS2_k127_73473_38 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000005277 101.0
CMS2_k127_73473_39 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000000007506 65.0
CMS2_k127_73473_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.033e-205 665.0
CMS2_k127_73473_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 4.454e-202 654.0
CMS2_k127_73473_6 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 579.0
CMS2_k127_73473_7 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 580.0
CMS2_k127_73473_8 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 549.0
CMS2_k127_73473_9 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 544.0
CMS2_k127_735445_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 7.641e-254 799.0
CMS2_k127_735445_1 transport systems, ATPase components K02056 - 3.6.3.17 6.85e-252 785.0
CMS2_k127_735445_10 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 602.0
CMS2_k127_735445_11 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 567.0
CMS2_k127_735445_12 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 562.0
CMS2_k127_735445_13 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 535.0
CMS2_k127_735445_14 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 521.0
CMS2_k127_735445_15 Basic membrane lipoprotein K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 506.0
CMS2_k127_735445_16 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 492.0
CMS2_k127_735445_17 PFAM cyclase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 507.0
CMS2_k127_735445_18 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 503.0
CMS2_k127_735445_19 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 483.0
CMS2_k127_735445_2 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 2.086e-251 792.0
CMS2_k127_735445_20 Glycerol-3-phosphate dehydrogenase K04940 - 1.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 467.0
CMS2_k127_735445_21 Methionine gamma-lyase K01761 - 4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 481.0
CMS2_k127_735445_22 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 456.0
CMS2_k127_735445_23 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 425.0
CMS2_k127_735445_24 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 402.0
CMS2_k127_735445_25 Putative aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 382.0
CMS2_k127_735445_26 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 370.0
CMS2_k127_735445_27 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 361.0
CMS2_k127_735445_28 ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 320.0
CMS2_k127_735445_29 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 290.0
CMS2_k127_735445_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K02182 - 6.2.1.48 1.042e-242 760.0
CMS2_k127_735445_30 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002569 272.0
CMS2_k127_735445_31 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001769 268.0
CMS2_k127_735445_32 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000133 243.0
CMS2_k127_735445_33 Transcriptional regulator, AsnC family K03719 - - 0.00000000000000000000000000000000000000000000000000000000000003492 218.0
CMS2_k127_735445_34 - - - - 0.0000000000000000000000000000000000000000003098 158.0
CMS2_k127_735445_4 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 8.067e-241 755.0
CMS2_k127_735445_5 Amp-dependent synthetase and ligase K08295 - 6.2.1.32 1.008e-225 711.0
CMS2_k127_735445_6 Short-chain dehydrogenase reductase sdr - - - 4.182e-220 708.0
CMS2_k127_735445_7 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 1.032e-218 710.0
CMS2_k127_735445_8 peptidase dimerisation domain protein - - - 2.423e-217 680.0
CMS2_k127_735445_9 acetyl-coa acetyltransferase - - - 1.481e-208 653.0
CMS2_k127_75780_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1308.0
CMS2_k127_75780_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1280.0
CMS2_k127_75780_10 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 599.0
CMS2_k127_75780_11 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 571.0
CMS2_k127_75780_12 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 572.0
CMS2_k127_75780_13 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 547.0
CMS2_k127_75780_14 Lytic transglycosylase K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 544.0
CMS2_k127_75780_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 512.0
CMS2_k127_75780_16 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 507.0
CMS2_k127_75780_17 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 499.0
CMS2_k127_75780_18 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 488.0
CMS2_k127_75780_19 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 442.0
CMS2_k127_75780_2 5'-nucleotidase, C-terminal domain K11751,K17224 - 3.1.3.5,3.6.1.45 4.191e-284 884.0
CMS2_k127_75780_20 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 447.0
CMS2_k127_75780_21 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 436.0
CMS2_k127_75780_22 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 426.0
CMS2_k127_75780_23 Protein of unknown function (DUF2863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 430.0
CMS2_k127_75780_24 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 406.0
CMS2_k127_75780_25 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 406.0
CMS2_k127_75780_26 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 386.0
CMS2_k127_75780_27 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 367.0
CMS2_k127_75780_28 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 362.0
CMS2_k127_75780_29 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 358.0
CMS2_k127_75780_3 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 7.746e-266 828.0
CMS2_k127_75780_30 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 356.0
CMS2_k127_75780_31 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 351.0
CMS2_k127_75780_32 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 368.0
CMS2_k127_75780_33 COG0437 Fe-S-cluster-containing hydrogenase components 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 360.0
CMS2_k127_75780_34 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 332.0
CMS2_k127_75780_35 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 318.0
CMS2_k127_75780_36 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 312.0
CMS2_k127_75780_37 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 307.0
CMS2_k127_75780_38 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 301.0
CMS2_k127_75780_39 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 289.0
CMS2_k127_75780_4 Cytochrome b(N-terminal)/b6/petB - - - 4.583e-239 754.0
CMS2_k127_75780_40 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001317 281.0
CMS2_k127_75780_41 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily K00001,K00344 - 1.1.1.1,1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006834 277.0
CMS2_k127_75780_42 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000016 279.0
CMS2_k127_75780_43 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004817 265.0
CMS2_k127_75780_44 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000001129 245.0
CMS2_k127_75780_45 metal-dependent enzyme of the double-stranded beta helix superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000004649 254.0
CMS2_k127_75780_46 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002787 252.0
CMS2_k127_75780_47 Thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002683 231.0
CMS2_k127_75780_48 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000002469 231.0
CMS2_k127_75780_49 - - - - 0.00000000000000000000000000000000000000000000000000000003683 198.0
CMS2_k127_75780_5 Belongs to the aldehyde dehydrogenase family K00128 GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009698,GO:0009699,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019438,GO:0019748,GO:0044237,GO:0044249,GO:0044550,GO:0050269,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901576 1.2.1.3 5.659e-208 660.0
CMS2_k127_75780_50 DMSO reductase anchor subunit (DmsC) K18363 - - 0.0000000000000000000000000000000000000000000000000002249 197.0
CMS2_k127_75780_51 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000000000000000000000000002719 201.0
CMS2_k127_75780_52 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000002834 192.0
CMS2_k127_75780_53 - - - - 0.00000000000000000000000000000000000000000000000008475 179.0
CMS2_k127_75780_54 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000001224 176.0
CMS2_k127_75780_55 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000000000003573 168.0
CMS2_k127_75780_56 Thioesterase - - - 0.000000000000000000000000000000000000000000007607 167.0
CMS2_k127_75780_57 Haem-degrading - - - 0.000000000000000000000000000000000000000001354 179.0
CMS2_k127_75780_58 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000007379 154.0
CMS2_k127_75780_59 Domain of Unknown Function (DUF349) - - - 0.0000000000000000000000000000000000001124 164.0
CMS2_k127_75780_6 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 5.593e-206 668.0
CMS2_k127_75780_60 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000003625 159.0
CMS2_k127_75780_61 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000142 162.0
CMS2_k127_75780_62 transcriptional regulator - - - 0.000000000000000000000000000000000003255 142.0
CMS2_k127_75780_63 - - - - 0.00000000000000000000000000000000003732 155.0
CMS2_k127_75780_64 MarR family - - - 0.0000000000000000000000000000000002662 139.0
CMS2_k127_75780_65 Rubrerythrin - - - 0.000000000000000000000000000000002647 145.0
CMS2_k127_75780_66 Universal stress protein family - - - 0.0000000000000000000000000000000157 144.0
CMS2_k127_75780_67 Pfam:DUF59 - - - 0.0000000000000000000000111 115.0
CMS2_k127_75780_68 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000002154 102.0
CMS2_k127_75780_69 COG3121 P pilus assembly protein, chaperone PapD K07346 - - 0.000000000000000000206 97.0
CMS2_k127_75780_7 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 7.834e-202 644.0
CMS2_k127_75780_70 - - - - 0.0000000000002075 74.0
CMS2_k127_75780_71 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000448 68.0
CMS2_k127_75780_72 Cytochrome oxidase assembly protein K02259 - - 0.000000009262 69.0
CMS2_k127_75780_73 Secreted protein - - - 0.0004983 49.0
CMS2_k127_75780_8 Sulfate transporter antisigma-factor antagonist STAS - - - 4.173e-200 646.0
CMS2_k127_75780_9 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 594.0
CMS2_k127_925779_1 - - - - 0.0000000000001616 72.0
CMS2_k127_938604_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 2833.0
CMS2_k127_938604_1 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000001539 176.0
CMS2_k127_938604_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000002597 111.0