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Overview

ID MAG00458
Name CMS2_bin.71
Sample SMP0011
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Bathyarchaeia
Order Bathyarchaeales
Family Bathycorpusculaceae
Genus UBA11855
Species
Assembly information
Completeness (%) 97.57
Contamination (%) 2.67
GC content (%) 43.0
N50 (bp) 34,495
Genome size (bp) 2,092,791

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1646

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_102098_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.191e-205 652.0
CMS2_k127_102098_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 607.0
CMS2_k127_102098_10 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001979 282.0
CMS2_k127_102098_11 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008699 284.0
CMS2_k127_102098_12 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000003468 240.0
CMS2_k127_102098_13 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000001656 237.0
CMS2_k127_102098_14 Chorismate mutase type II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000002561 239.0
CMS2_k127_102098_15 Helix-turn-helix domain K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000001415 232.0
CMS2_k127_102098_16 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000006163 205.0
CMS2_k127_102098_17 TIGRFAM Shikimate kinase K00891 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.71 0.00000000000000000000000000000000000000000000000000000005303 206.0
CMS2_k127_102098_18 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000001418 200.0
CMS2_k127_102098_19 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000004349 130.0
CMS2_k127_102098_2 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 575.0
CMS2_k127_102098_20 Prephenate dehydratase K14170 GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51,5.4.99.5 0.0000000000125 68.0
CMS2_k127_102098_21 membrane-associated protein domain - - - 0.0000001982 60.0
CMS2_k127_102098_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 564.0
CMS2_k127_102098_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 511.0
CMS2_k127_102098_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 435.0
CMS2_k127_102098_6 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 406.0
CMS2_k127_102098_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 326.0
CMS2_k127_102098_8 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 312.0
CMS2_k127_102098_9 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 297.0
CMS2_k127_1024284_0 Domain of unknown function (DUF4070) - - - 0.00000000000000000004053 89.0
CMS2_k127_1024284_1 - - - - 0.0001123 48.0
CMS2_k127_1035701_0 peptidase - - - 0.000000000000000000000000000000000000000001127 166.0
CMS2_k127_1035701_1 - - - - 0.0000000000000000002404 93.0
CMS2_k127_1035701_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000002697 92.0
CMS2_k127_1035701_3 integral membrane protein K07027 - - 0.000000000141 73.0
CMS2_k127_1035701_4 deoxyhypusine monooxygenase activity - - - 0.0000179 51.0
CMS2_k127_1035701_5 Carboxypeptidase regulatory-like domain - - - 0.0001224 53.0
CMS2_k127_109269_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 3.973e-249 779.0
CMS2_k127_109269_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 569.0
CMS2_k127_109269_10 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 302.0
CMS2_k127_109269_11 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 290.0
CMS2_k127_109269_12 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 289.0
CMS2_k127_109269_13 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007507 265.0
CMS2_k127_109269_14 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000005261 251.0
CMS2_k127_109269_15 K02028 polar amino acid transport system ATP-binding protein K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000003747 252.0
CMS2_k127_109269_16 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000489 237.0
CMS2_k127_109269_17 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000001531 218.0
CMS2_k127_109269_18 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000001365 218.0
CMS2_k127_109269_19 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000001866 212.0
CMS2_k127_109269_2 TIGRFAM lysine 2,3-aminomutase YodO family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 484.0
CMS2_k127_109269_20 tRNA (Uracil-5-)-methyltransferase - - - 0.00000000000000000000000000000000000000000000000001681 186.0
CMS2_k127_109269_21 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.000000000000000000000000000000000000000003562 162.0
CMS2_k127_109269_22 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000007137 132.0
CMS2_k127_109269_23 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000003397 129.0
CMS2_k127_109269_24 Belongs to the eukaryotic ribosomal protein eL14 family K02875 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000003703 122.0
CMS2_k127_109269_25 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.00000000000000000000000002397 119.0
CMS2_k127_109269_26 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000503 112.0
CMS2_k127_109269_27 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.00000000000000000001453 94.0
CMS2_k127_109269_28 Bacterio-opsin activator HTH K06930 - - 0.0000000000000001063 88.0
CMS2_k127_109269_29 Transcriptional regulator PadR-like family - - - 0.00000000000133 76.0
CMS2_k127_109269_3 component I K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 460.0
CMS2_k127_109269_30 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000001088 56.0
CMS2_k127_109269_31 Lrp/AsnC ligand binding domain - - - 0.00004476 52.0
CMS2_k127_109269_32 DEAD DEAH box helicase K03724 - - 0.000131 49.0
CMS2_k127_109269_4 helicase superfamily c-terminal domain K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 392.0
CMS2_k127_109269_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 360.0
CMS2_k127_109269_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 352.0
CMS2_k127_109269_7 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 356.0
CMS2_k127_109269_8 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 353.0
CMS2_k127_109269_9 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 299.0
CMS2_k127_1165823_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 5.891e-272 859.0
CMS2_k127_1165823_1 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 496.0
CMS2_k127_1165823_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000002669 147.0
CMS2_k127_1165823_11 Protein of unknown function (DUF454) K09790 - - 0.000000000000000000000000000000000008266 140.0
CMS2_k127_1165823_12 Conserved protein implicated in secretion - - - 0.00000000000000000000000000000000005992 141.0
CMS2_k127_1165823_13 methyltransferase activity - - - 0.0000000000000000000000000000000005407 138.0
CMS2_k127_1165823_14 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000003886 125.0
CMS2_k127_1165823_15 - - - - 0.0000000000000000000000000001536 119.0
CMS2_k127_1165823_16 Mo-co oxidoreductase dimerisation domain K17225 - - 0.000000002482 67.0
CMS2_k127_1165823_17 transcriptional - - - 0.0000004864 61.0
CMS2_k127_1165823_18 glucosylceramidase activity - - - 0.00002025 51.0
CMS2_k127_1165823_2 resolution of meiotic recombination intermediates - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 322.0
CMS2_k127_1165823_3 HMGL-like K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000004889 264.0
CMS2_k127_1165823_4 Prokaryotic glutathione synthetase, ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006017 239.0
CMS2_k127_1165823_5 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000002952 230.0
CMS2_k127_1165823_6 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000003088 201.0
CMS2_k127_1165823_7 Domain of unknown function DUF108 K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000001887 197.0
CMS2_k127_1165823_8 AIR synthase related protein, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000004977 194.0
CMS2_k127_1165823_9 Thiamine transporter YuaJ K16789 - - 0.000000000000000000000000000000000000000004305 161.0
CMS2_k127_1183611_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 5.834e-229 730.0
CMS2_k127_1183611_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 4.75e-227 716.0
CMS2_k127_1183611_10 ABC-type Fe3 transport system permease component K02053,K02054,K02063 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000405 297.0
CMS2_k127_1183611_11 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000001233 272.0
CMS2_k127_1183611_12 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001548 215.0
CMS2_k127_1183611_13 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000008309 226.0
CMS2_k127_1183611_14 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000001169 201.0
CMS2_k127_1183611_15 RibD C-terminal domain K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000000009776 194.0
CMS2_k127_1183611_16 Phosphoribosyl transferase domain K00759,K09685 - 2.4.2.7 0.00000000000000000000000000000000000000000000000001168 188.0
CMS2_k127_1183611_17 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K14835 GO:0000027,GO:0000154,GO:0000470,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0006139,GO:0006355,GO:0006357,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008284,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009889,GO:0009966,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010646,GO:0016043,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0019219,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0023051,GO:0031167,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042127,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070013,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0140098,GO:0140102,GO:1901360,GO:1901796,GO:1902531,GO:1903506,GO:2000112,GO:2001141 2.1.1.310 0.000000000000000000000000000000000000000000000001464 186.0
CMS2_k127_1183611_18 PFAM GAF domain K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000002031 172.0
CMS2_k127_1183611_19 PAC2 family K07159 - - 0.0000000000000000000000000000000000000001593 160.0
CMS2_k127_1183611_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 448.0
CMS2_k127_1183611_20 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000007375 150.0
CMS2_k127_1183611_21 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.000000000000000000000000000000001179 137.0
CMS2_k127_1183611_22 RDD family - - - 0.0000000000000000000000004006 112.0
CMS2_k127_1183611_23 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000004039 110.0
CMS2_k127_1183611_24 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000000009382 94.0
CMS2_k127_1183611_25 toxin-antitoxin pair type II binding - - - 0.00000000000000000003022 92.0
CMS2_k127_1183611_26 PFAM peptidase U32 K08303 - - 0.00000000000000002155 84.0
CMS2_k127_1183611_27 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000000000000002768 83.0
CMS2_k127_1183611_28 Predicted membrane protein (DUF2085) - - - 0.00000000000001387 79.0
CMS2_k127_1183611_29 PFAM regulatory protein AsnC Lrp family - - - 0.000000000002803 71.0
CMS2_k127_1183611_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 410.0
CMS2_k127_1183611_30 Transcription factor zinc-finger - - - 0.000000000007065 74.0
CMS2_k127_1183611_31 PUA domain K07565 - - 0.0000001315 59.0
CMS2_k127_1183611_32 Belongs to the 'phage' integrase family - - - 0.0000003482 61.0
CMS2_k127_1183611_33 - - - - 0.0001561 44.0
CMS2_k127_1183611_34 PQQ-like domain - - - 0.0005886 53.0
CMS2_k127_1183611_35 - - - - 0.0008503 49.0
CMS2_k127_1183611_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 351.0
CMS2_k127_1183611_5 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 309.0
CMS2_k127_1183611_6 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 302.0
CMS2_k127_1183611_7 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 301.0
CMS2_k127_1183611_8 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 304.0
CMS2_k127_1183611_9 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 295.0
CMS2_k127_1227382_0 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006068 272.0
CMS2_k127_1227382_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000005448 174.0
CMS2_k127_1227382_2 - - - - 0.000001483 52.0
CMS2_k127_1267877_0 DEAD DEAH box helicase domain protein K03724 - - 4.13e-252 808.0
CMS2_k127_1267877_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 342.0
CMS2_k127_1267877_10 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000001319 172.0
CMS2_k127_1267877_11 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000009847 164.0
CMS2_k127_1267877_12 Methyltransferase domain - - - 0.0000000000000000000000000000000000002302 150.0
CMS2_k127_1267877_13 Putative TM nitroreductase - - - 0.000000000000000000000000000000000003925 142.0
CMS2_k127_1267877_14 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000002464 136.0
CMS2_k127_1267877_15 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000004714 127.0
CMS2_k127_1267877_16 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000004081 113.0
CMS2_k127_1267877_17 SMART serine threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase K01090 - 3.1.3.16 0.0000000000000000000000002679 115.0
CMS2_k127_1267877_18 PFAM CBS domain containing protein - - - 0.000000000000000000000001781 107.0
CMS2_k127_1267877_19 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000000000003841 97.0
CMS2_k127_1267877_2 PFAM glycosidase, PH1107-related K20885 - 2.4.1.339,2.4.1.340 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003399 285.0
CMS2_k127_1267877_20 - - - - 0.00000000000000000001913 95.0
CMS2_k127_1267877_21 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000313 77.0
CMS2_k127_1267877_22 Periplasmic copper-binding protein (NosD) - - - 0.00000000005477 75.0
CMS2_k127_1267877_23 membrane - - - 0.00000000008949 70.0
CMS2_k127_1267877_24 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000004085 68.0
CMS2_k127_1267877_25 PFAM conserved K07027 - - 0.00000001281 66.0
CMS2_k127_1267877_26 Right handed beta helix region - - - 0.0000001308 59.0
CMS2_k127_1267877_27 Belongs to the eukaryotic ribosomal protein eL38 family K02923 - - 0.000006607 51.0
CMS2_k127_1267877_28 Phage integrase family - - - 0.00002208 56.0
CMS2_k127_1267877_29 Pyrrolo-quinoline quinone - - - 0.0005197 53.0
CMS2_k127_1267877_30 protein conserved in archaea K09732 - - 0.0007555 45.0
CMS2_k127_1267877_4 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000001175 273.0
CMS2_k127_1267877_5 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003974 260.0
CMS2_k127_1267877_6 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000004877 256.0
CMS2_k127_1267877_7 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000005506 236.0
CMS2_k127_1267877_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000004544 212.0
CMS2_k127_1267877_9 methylase K07446 - 2.1.1.213 0.00000000000000000000000000000000000000000000001749 184.0
CMS2_k127_1280412_0 Belongs to the peptidase S16 family - - - 2.903e-315 984.0
CMS2_k127_1280412_1 Belongs to the glutamate synthase family - - - 6.061e-231 724.0
CMS2_k127_1280412_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000002409 238.0
CMS2_k127_1280412_11 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000018 199.0
CMS2_k127_1280412_12 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000001169 201.0
CMS2_k127_1280412_13 4Fe-4S ferredoxin iron-sulfur binding domain protein K00196 - - 0.0000000000000000000000000000000000000000000000000000002583 196.0
CMS2_k127_1280412_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000005916 184.0
CMS2_k127_1280412_15 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000000000000000008303 189.0
CMS2_k127_1280412_16 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.00000000000000000000000000000000000000000000001585 183.0
CMS2_k127_1280412_17 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000111 162.0
CMS2_k127_1280412_18 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000002833 150.0
CMS2_k127_1280412_19 PFAM Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000001364 139.0
CMS2_k127_1280412_2 Glutamate synthase - - - 2.59e-227 715.0
CMS2_k127_1280412_20 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002757 132.0
CMS2_k127_1280412_21 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000001126 129.0
CMS2_k127_1280412_22 4Fe-4S dicluster domain - - - 0.000000000000000000000000000002068 126.0
CMS2_k127_1280412_23 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.00000000000000000000000000003904 123.0
CMS2_k127_1280412_24 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000000000001029 108.0
CMS2_k127_1280412_25 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.0000000000000000000002902 97.0
CMS2_k127_1280412_27 TIGRFAM MoaD family protein K03636 - - 0.000001381 54.0
CMS2_k127_1280412_28 - - - - 0.00008068 48.0
CMS2_k127_1280412_3 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 510.0
CMS2_k127_1280412_4 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 449.0
CMS2_k127_1280412_5 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 445.0
CMS2_k127_1280412_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 389.0
CMS2_k127_1280412_7 GXGXG motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001012 271.0
CMS2_k127_1280412_8 ATP binding protein K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000001003 258.0
CMS2_k127_1280412_9 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000001029 252.0
CMS2_k127_1293777_0 PFAM Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 557.0
CMS2_k127_1293777_1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 323.0
CMS2_k127_1293777_2 - - - - 0.00000000000003562 82.0
CMS2_k127_1351687_0 PFAM Amidohydrolase 3 K00200 - 1.2.7.12 2.393e-197 630.0
CMS2_k127_1351687_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 502.0
CMS2_k127_1351687_10 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 303.0
CMS2_k127_1351687_11 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 302.0
CMS2_k127_1351687_12 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 310.0
CMS2_k127_1351687_13 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005116 273.0
CMS2_k127_1351687_14 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000002412 272.0
CMS2_k127_1351687_15 ABC transporter, ATP-binding protein K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000957 254.0
CMS2_k127_1351687_16 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000001803 244.0
CMS2_k127_1351687_17 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000003515 240.0
CMS2_k127_1351687_18 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000003176 237.0
CMS2_k127_1351687_19 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000001409 229.0
CMS2_k127_1351687_2 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 485.0
CMS2_k127_1351687_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001785 227.0
CMS2_k127_1351687_21 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000003031 226.0
CMS2_k127_1351687_22 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000001002 218.0
CMS2_k127_1351687_23 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000001253 191.0
CMS2_k127_1351687_24 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000008041 191.0
CMS2_k127_1351687_25 formylmethanofuran dehydrogenase, subunit C K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000003668 179.0
CMS2_k127_1351687_26 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000007804 177.0
CMS2_k127_1351687_27 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000005025 172.0
CMS2_k127_1351687_28 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000006281 166.0
CMS2_k127_1351687_29 FdhD/NarQ family K02379 - - 0.000000000000000000000000000000000000000004059 165.0
CMS2_k127_1351687_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 489.0
CMS2_k127_1351687_30 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000001003 149.0
CMS2_k127_1351687_31 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 - 2.7.7.3 0.00000000000000000000000000000000001974 140.0
CMS2_k127_1351687_32 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000004671 132.0
CMS2_k127_1351687_33 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000000000000000005302 132.0
CMS2_k127_1351687_34 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000003796 134.0
CMS2_k127_1351687_35 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.000000000000000000000000000002769 124.0
CMS2_k127_1351687_36 Adenosylcobinamide amidohydrolase - - - 0.000000000000000000000000000004597 133.0
CMS2_k127_1351687_37 - - - - 0.00000000000000000000000000009509 124.0
CMS2_k127_1351687_38 Thioesterase superfamily K02614 - - 0.0000000000000000000000000008708 116.0
CMS2_k127_1351687_39 Cupin domain - - - 0.00000000000000000000000006816 113.0
CMS2_k127_1351687_4 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 473.0
CMS2_k127_1351687_40 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000002215 113.0
CMS2_k127_1351687_41 Transcriptional regulator K07332 - - 0.0000000000000000000001124 105.0
CMS2_k127_1351687_42 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000007437 98.0
CMS2_k127_1351687_44 PFAM NurA domain - - - 0.000000000000000603 89.0
CMS2_k127_1351687_45 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000001891 85.0
CMS2_k127_1351687_46 TIGRFAM cytidyltransferase-related domain K14656 - 2.7.7.2 0.00000000001954 67.0
CMS2_k127_1351687_47 lysine biosynthetic process via aminoadipic acid K05826 - - 0.00000217 51.0
CMS2_k127_1351687_5 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 455.0
CMS2_k127_1351687_6 COG0433 Predicted ATPase K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 400.0
CMS2_k127_1351687_7 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 396.0
CMS2_k127_1351687_8 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 387.0
CMS2_k127_1351687_9 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 342.0
CMS2_k127_1399553_0 RelA SpoT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 543.0
CMS2_k127_1399553_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002554 252.0
CMS2_k127_1399553_3 Transposase, Mutator family - - - 0.000000008543 56.0
CMS2_k127_1514946_0 Tyrosine--tRNA ligase K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 421.0
CMS2_k127_1514946_1 Cysteine synthase K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000001256 204.0
CMS2_k127_1514975_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 2.246e-225 710.0
CMS2_k127_1514975_1 Beta-galactosidase - - - 0.00000000000000000000000002413 121.0
CMS2_k127_1514975_3 Acts probably as a methyl group carrier between MttB and either MtbA or MtaA K14084 - - 0.00006125 48.0
CMS2_k127_1522620_0 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000004809 184.0
CMS2_k127_1522620_1 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000004727 186.0
CMS2_k127_1522620_2 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000001269 181.0
CMS2_k127_1522620_3 - K00960 - 2.7.7.6 0.0000000000004241 69.0
CMS2_k127_1522620_4 - - - - 0.00000001038 62.0
CMS2_k127_1549086_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 3.192e-308 980.0
CMS2_k127_1549086_1 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 563.0
CMS2_k127_1549086_10 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 399.0
CMS2_k127_1549086_11 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 377.0
CMS2_k127_1549086_12 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 344.0
CMS2_k127_1549086_13 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 343.0
CMS2_k127_1549086_14 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 339.0
CMS2_k127_1549086_15 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 327.0
CMS2_k127_1549086_16 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 321.0
CMS2_k127_1549086_17 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 323.0
CMS2_k127_1549086_18 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 315.0
CMS2_k127_1549086_19 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 297.0
CMS2_k127_1549086_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 545.0
CMS2_k127_1549086_20 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001122 291.0
CMS2_k127_1549086_21 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000003704 268.0
CMS2_k127_1549086_22 50S ribosomal protein L4 K02930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000231 261.0
CMS2_k127_1549086_23 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001062 267.0
CMS2_k127_1549086_24 Queuosine biosynthesis protein QueC K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002686 253.0
CMS2_k127_1549086_25 PFAM Oxidoreductase K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000000000000000001401 252.0
CMS2_k127_1549086_26 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000121 236.0
CMS2_k127_1549086_27 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000005162 233.0
CMS2_k127_1549086_28 transferase hexapeptide repeat containing protein K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000006389 235.0
CMS2_k127_1549086_29 Methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000005792 230.0
CMS2_k127_1549086_3 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 509.0
CMS2_k127_1549086_30 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000007658 227.0
CMS2_k127_1549086_31 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000004655 217.0
CMS2_k127_1549086_32 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000002396 211.0
CMS2_k127_1549086_33 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000006051 195.0
CMS2_k127_1549086_34 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000000000004228 190.0
CMS2_k127_1549086_35 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000009096 196.0
CMS2_k127_1549086_36 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000003023 178.0
CMS2_k127_1549086_37 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000003715 188.0
CMS2_k127_1549086_38 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000002042 179.0
CMS2_k127_1549086_39 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000008797 179.0
CMS2_k127_1549086_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 498.0
CMS2_k127_1549086_40 Predicted membrane protein (DUF2070) K08979 - - 0.000000000000000000000000000000000000000000002403 185.0
CMS2_k127_1549086_41 UDP binding domain K02474 - - 0.00000000000000000000000000000000000000000004374 177.0
CMS2_k127_1549086_42 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.00000000000000000000000000000000000000000005523 168.0
CMS2_k127_1549086_43 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000004043 165.0
CMS2_k127_1549086_44 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000004957 168.0
CMS2_k127_1549086_45 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000009638 154.0
CMS2_k127_1549086_46 Lysine methyltransferase K02493 - 2.1.1.297 0.000000000000000000000000000000000000002711 153.0
CMS2_k127_1549086_47 Beta-galactosidase - - - 0.000000000000000000000000000000000002829 149.0
CMS2_k127_1549086_48 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000003606 141.0
CMS2_k127_1549086_49 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000007869 141.0
CMS2_k127_1549086_5 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 475.0
CMS2_k127_1549086_50 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000227 145.0
CMS2_k127_1549086_51 - - - - 0.000000000000000000000000000000003209 140.0
CMS2_k127_1549086_52 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000000000187 131.0
CMS2_k127_1549086_53 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000001449 131.0
CMS2_k127_1549086_54 MazG nucleotide pyrophosphohydrolase domain - - - 0.0000000000000000000000000000003097 125.0
CMS2_k127_1549086_55 Belongs to the UPF0218 family K09735 - - 0.000000000000000000000000000007738 125.0
CMS2_k127_1549086_56 PFAM Translin K07477 - - 0.00000000000000000000000000001132 126.0
CMS2_k127_1549086_57 Adenosylcobinamide amidohydrolase - - - 0.000000000000000000000000001274 124.0
CMS2_k127_1549086_58 Domain of unknown function (DUF4443) - - - 0.000000000000000000000000003224 119.0
CMS2_k127_1549086_59 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000008408 112.0
CMS2_k127_1549086_6 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 471.0
CMS2_k127_1549086_60 PFAM Trm112p-like protein - - - 0.0000000000000000000000004243 106.0
CMS2_k127_1549086_61 PIN domain of ribonuclease K07060 - - 0.0000000000000000000000008071 110.0
CMS2_k127_1549086_62 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000003614 98.0
CMS2_k127_1549086_63 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000468 97.0
CMS2_k127_1549086_64 Large family of predicted nucleotide-binding domains K07158 - - 0.0000000000000000001501 93.0
CMS2_k127_1549086_65 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000000000005857 84.0
CMS2_k127_1549086_66 - - - - 0.0000000000000000654 86.0
CMS2_k127_1549086_67 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000009054 71.0
CMS2_k127_1549086_68 - - - - 0.00000000003415 66.0
CMS2_k127_1549086_69 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000003915 67.0
CMS2_k127_1549086_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 471.0
CMS2_k127_1549086_70 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000004607 67.0
CMS2_k127_1549086_71 PFAM Transcription elongation factor Elf1 like - - - 0.00000000006077 68.0
CMS2_k127_1549086_72 Sec61beta family - - - 0.000000007295 58.0
CMS2_k127_1549086_73 - - - - 0.00000003189 60.0
CMS2_k127_1549086_74 - - - - 0.000000227 63.0
CMS2_k127_1549086_75 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0000003915 55.0
CMS2_k127_1549086_76 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000001509 54.0
CMS2_k127_1549086_77 transmembrane transporter activity K08225 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015562,GO:0022857,GO:0042221,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - 0.000002493 59.0
CMS2_k127_1549086_78 PDGLE domain K02009 - - 0.0000551 49.0
CMS2_k127_1549086_79 - - - - 0.0001065 48.0
CMS2_k127_1549086_8 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 419.0
CMS2_k127_1549086_80 - - - - 0.0001782 52.0
CMS2_k127_1549086_82 GINS complex protein K09723 - - 0.0008026 49.0
CMS2_k127_1549086_9 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 398.0
CMS2_k127_1578475_0 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 9.41e-200 632.0
CMS2_k127_1578475_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 566.0
CMS2_k127_1578475_10 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002473 295.0
CMS2_k127_1578475_11 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006376 281.0
CMS2_k127_1578475_12 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006775 278.0
CMS2_k127_1578475_13 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009699 271.0
CMS2_k127_1578475_14 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000543 261.0
CMS2_k127_1578475_15 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000004054 260.0
CMS2_k127_1578475_16 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000231 242.0
CMS2_k127_1578475_17 Sodium hydrogen exchanger K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000007718 234.0
CMS2_k127_1578475_18 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000003357 211.0
CMS2_k127_1578475_19 Formamidopyrimidine-DNA glycosylase H2TH domain - - - 0.000000000000000000000000000000000000000000000002515 181.0
CMS2_k127_1578475_2 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 514.0
CMS2_k127_1578475_20 TIGRFAM 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase K00004,K00008,K00060 - 1.1.1.103,1.1.1.14,1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000003065 179.0
CMS2_k127_1578475_21 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000004345 170.0
CMS2_k127_1578475_22 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000000000000000001561 168.0
CMS2_k127_1578475_23 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000002718 168.0
CMS2_k127_1578475_24 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000239 162.0
CMS2_k127_1578475_25 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000000000000001407 158.0
CMS2_k127_1578475_26 SOUL heme-binding protein - - - 0.000000000000000000000000000000000000001588 153.0
CMS2_k127_1578475_27 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000005273 148.0
CMS2_k127_1578475_28 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000006328 144.0
CMS2_k127_1578475_29 CBS domain K03498 - - 0.00000000000000000000000000000000003939 151.0
CMS2_k127_1578475_3 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 388.0
CMS2_k127_1578475_30 PFAM Nitroreductase - - - 0.00000000000000000000000000000000008243 139.0
CMS2_k127_1578475_31 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000005088 134.0
CMS2_k127_1578475_32 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000001864 125.0
CMS2_k127_1578475_33 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K03658,K07466 - 3.6.4.12 0.000000000000000000000000001019 119.0
CMS2_k127_1578475_34 subfamily IA, variant 3 with third motif having DD or ED - - - 0.000000000000000000000000003202 119.0
CMS2_k127_1578475_35 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant K01091 - 3.1.3.18 0.00000000000000000000002294 110.0
CMS2_k127_1578475_36 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000001088 99.0
CMS2_k127_1578475_37 Belongs to the UPF0201 family K09736 - - 0.000000000000000000002479 98.0
CMS2_k127_1578475_38 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000002486 101.0
CMS2_k127_1578475_39 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000003681 98.0
CMS2_k127_1578475_4 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 349.0
CMS2_k127_1578475_40 Transcriptional regulator K02019,K03574,K03750,K07219 - 2.10.1.1,3.6.1.55 0.000000000000000000009676 99.0
CMS2_k127_1578475_41 integral membrane protein K07027 - - 0.00000000000000000004307 103.0
CMS2_k127_1578475_42 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00000000000000000005873 95.0
CMS2_k127_1578475_43 TOBE domain - - - 0.000000000000002426 83.0
CMS2_k127_1578475_44 - - - - 0.00000000000002016 80.0
CMS2_k127_1578475_45 - - - - 0.00000000000002143 80.0
CMS2_k127_1578475_46 Zn-dependent hydrolase of beta-lactamase fold - - - 0.00000000000022 79.0
CMS2_k127_1578475_47 Pfam:DUF59 - - - 0.00000000001742 70.0
CMS2_k127_1578475_48 - - - - 0.00000003088 57.0
CMS2_k127_1578475_49 - - - - 0.0000009395 59.0
CMS2_k127_1578475_5 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 345.0
CMS2_k127_1578475_50 cell adhesion involved in biofilm formation - - - 0.00002513 57.0
CMS2_k127_1578475_51 N-4 methylation of cytosine - - - 0.00003431 51.0
CMS2_k127_1578475_53 - - - - 0.0002515 52.0
CMS2_k127_1578475_54 Signal peptidase K13280 - 3.4.21.89 0.0005153 50.0
CMS2_k127_1578475_55 Mut7-C RNAse domain - - - 0.0008835 45.0
CMS2_k127_1578475_6 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 328.0
CMS2_k127_1578475_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 320.0
CMS2_k127_1578475_8 Membrane protein of 12 TMs K01992,K07087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 307.0
CMS2_k127_1578475_9 PFAM Sugar isomerase (SIS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001548 290.0
CMS2_k127_1616437_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 370.0
CMS2_k127_1616437_1 - - - - 0.00000000000000000000000000000000000000000000000001061 189.0
CMS2_k127_1616437_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000003716 135.0
CMS2_k127_1616437_4 PFAM SOUL heme-binding protein - - - 0.000001691 51.0
CMS2_k127_1646082_0 GYD domain - - - 0.00000000000000000001391 94.0
CMS2_k127_1646082_1 Universal stress protein - - - 0.0000000000000000005554 94.0
CMS2_k127_1646082_2 UbiA prenyltransferase family - - - 0.000000000001805 78.0
CMS2_k127_1646082_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000002 70.0
CMS2_k127_17434_0 COG0455 ATPases involved in chromosome partitioning K03496,K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000004085 235.0
CMS2_k127_17434_1 Flavodoxin domain - - - 0.000000000000000000000000000000000000000000000000001733 187.0
CMS2_k127_17434_2 KaiC - - - 0.000000000000000000000000000000000002344 147.0
CMS2_k127_17434_3 Belongs to the UPF0273 family - - - 0.0000000000000000000005639 106.0
CMS2_k127_17434_4 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000001872 66.0
CMS2_k127_17434_5 COG0738 Fucose permease - - - 0.00004328 55.0
CMS2_k127_17434_6 MFS/sugar transport protein - - - 0.00009259 53.0
CMS2_k127_1798750_0 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 1.205e-208 662.0
CMS2_k127_1798750_1 PFAM TCP-1 cpn60 chaperonin family K22447 - - 7.434e-202 642.0
CMS2_k127_1798750_10 Dimerisation domain - - - 0.000000000000000000000000003384 123.0
CMS2_k127_1798750_11 CAAX protease self-immunity K07052 - - 0.00000000000000000000002088 111.0
CMS2_k127_1798750_12 RNA-binding protein contains TRAM domain - - - 0.00000000000002105 75.0
CMS2_k127_1798750_13 - - - - 0.0000002918 57.0
CMS2_k127_1798750_14 - - - - 0.00004626 46.0
CMS2_k127_1798750_15 Domain of unknown function (DUF3463) - - - 0.0007936 44.0
CMS2_k127_1798750_2 response to heat K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 292.0
CMS2_k127_1798750_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 293.0
CMS2_k127_1798750_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009177 264.0
CMS2_k127_1798750_5 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004418 266.0
CMS2_k127_1798750_6 - - - - 0.00000000000000000000000000000000000000000002087 174.0
CMS2_k127_1798750_7 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000003073 152.0
CMS2_k127_1798750_8 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000005386 145.0
CMS2_k127_1798750_9 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000008457 118.0
CMS2_k127_2032598_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 352.0
CMS2_k127_2032598_1 Domain of unknown function (DUF3463) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004171 239.0
CMS2_k127_2032598_2 - - - - 0.000000000000000000009167 95.0
CMS2_k127_2032598_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000002192 91.0
CMS2_k127_2032598_4 RNA-binding protein contains TRAM domain - - - 0.000000000000003598 78.0
CMS2_k127_2032598_5 COG0058 Glucan phosphorylase - - - 0.00000000000003682 72.0
CMS2_k127_2032598_6 Domain of unknown function (DUF362) - - - 0.000000006541 66.0
CMS2_k127_2032598_7 - - - - 0.0003888 47.0
CMS2_k127_2056515_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.729e-312 975.0
CMS2_k127_2056515_1 glycoside hydrolase, family - - - 1.094e-289 965.0
CMS2_k127_2056515_10 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 325.0
CMS2_k127_2056515_11 5-dehydro-2-deoxygluconokinase K03338 - 2.7.1.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 304.0
CMS2_k127_2056515_12 Diphthamide K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000006992 263.0
CMS2_k127_2056515_13 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007639 262.0
CMS2_k127_2056515_14 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003011 260.0
CMS2_k127_2056515_15 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000003607 243.0
CMS2_k127_2056515_16 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000001037 243.0
CMS2_k127_2056515_17 PFAM TrkA-C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005307 241.0
CMS2_k127_2056515_18 MgtE integral membrane K07244 - - 0.000000000000000000000000000000000000000000000000000000000000001557 233.0
CMS2_k127_2056515_19 Translation initiation factor 2 K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000148 216.0
CMS2_k127_2056515_2 PFAM FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 573.0
CMS2_k127_2056515_20 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000004414 211.0
CMS2_k127_2056515_21 Translation initiation factor 2 K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000004205 202.0
CMS2_k127_2056515_22 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000000000000001254 197.0
CMS2_k127_2056515_23 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000002513 203.0
CMS2_k127_2056515_24 SMART zinc finger, RanBP2-type - - - 0.00000000000000000000000000000000000000000000000000004291 200.0
CMS2_k127_2056515_25 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000001153 192.0
CMS2_k127_2056515_26 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000891 186.0
CMS2_k127_2056515_27 Methyltransferase K07579 - - 0.00000000000000000000000000000000000000001799 161.0
CMS2_k127_2056515_28 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001367 153.0
CMS2_k127_2056515_29 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000003964 160.0
CMS2_k127_2056515_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 541.0
CMS2_k127_2056515_30 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000005717 152.0
CMS2_k127_2056515_31 lipolytic protein G-D-S-L family K00077 - 1.1.1.169 0.00000000000000000000000000000000000001379 152.0
CMS2_k127_2056515_32 Putative RNA methylase family UPF0020 - - - 0.00000000000000000000000000000000000001489 160.0
CMS2_k127_2056515_33 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000002808 155.0
CMS2_k127_2056515_34 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000009091 143.0
CMS2_k127_2056515_35 Acyltransferase family - - - 0.0000000000000000000000000000000007418 144.0
CMS2_k127_2056515_36 AraC-like ligand binding domain - - - 0.000000000000000000000000000003241 123.0
CMS2_k127_2056515_37 binds to the 23S rRNA K02929 - - 0.000000000000000000000000001806 114.0
CMS2_k127_2056515_38 - - - - 0.000000000000000000000001711 109.0
CMS2_k127_2056515_39 RNA polymerase subunit 9 K03057 - - 0.000000000000000000000003397 105.0
CMS2_k127_2056515_4 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 539.0
CMS2_k127_2056515_40 Belongs to the UPF0147 family K09721 - - 0.000000000000000000000003418 104.0
CMS2_k127_2056515_41 HD domain - - - 0.000000000000000000002816 103.0
CMS2_k127_2056515_42 molybdopterin-guanine dinucleotide biosynthesis protein K03635 - 2.8.1.12 0.0000000000000000001534 94.0
CMS2_k127_2056515_43 Ribonuclease III - - - 0.0000000000000000002709 92.0
CMS2_k127_2056515_44 Uncharacterized protein conserved in archaea (DUF2095) - - - 0.0000000000000000005811 90.0
CMS2_k127_2056515_45 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000000008566 81.0
CMS2_k127_2056515_46 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001234 78.0
CMS2_k127_2056515_47 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00176,K00338 - 1.2.7.3,1.6.5.3 0.000000000000007913 76.0
CMS2_k127_2056515_48 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.000000000000007962 79.0
CMS2_k127_2056515_49 phosphate transport K07220 - - 0.00000000000000861 83.0
CMS2_k127_2056515_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 490.0
CMS2_k127_2056515_50 Psort location Cytoplasmic, score - - - 0.0000000000004851 80.0
CMS2_k127_2056515_51 AAA domain K07028 - - 0.0000000000007335 76.0
CMS2_k127_2056515_52 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000000001654 67.0
CMS2_k127_2056515_53 protein conserved in archaea K09723 - - 0.000000006457 64.0
CMS2_k127_2056515_54 HTH DNA binding domain - - - 0.00000001096 61.0
CMS2_k127_2056515_55 membrane - - - 0.00000007644 64.0
CMS2_k127_2056515_56 Transcriptional regulator - - - 0.0000005936 57.0
CMS2_k127_2056515_57 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000002095 56.0
CMS2_k127_2056515_58 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000004447 55.0
CMS2_k127_2056515_59 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - - 0.000008018 58.0
CMS2_k127_2056515_6 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 432.0
CMS2_k127_2056515_61 COG4993 Glucose dehydrogenase K00114 - 1.1.2.8 0.0003749 54.0
CMS2_k127_2056515_62 Right handed beta helix region - - - 0.0008288 54.0
CMS2_k127_2056515_7 SMART zinc finger, RanBP2-type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 375.0
CMS2_k127_2056515_8 SMART Elongator protein 3 MiaB NifB K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 385.0
CMS2_k127_2056515_9 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 327.0
CMS2_k127_2079744_0 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 482.0
CMS2_k127_2079744_1 FAD dependent oxidoreductase K00109,K00111,K15736 - 1.1.5.3,1.1.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 467.0
CMS2_k127_2079744_10 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000004359 139.0
CMS2_k127_2079744_11 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000001092 141.0
CMS2_k127_2079744_12 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000007809 136.0
CMS2_k127_2079744_13 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000005272 123.0
CMS2_k127_2079744_14 membrane - - - 0.0000000000000000000000008893 111.0
CMS2_k127_2079744_15 queuine tRNA-ribosyltransferase activity - - - 0.00000000000000000000007344 101.0
CMS2_k127_2079744_16 Domain of unknown function (DUF3786) - - - 0.0000000000000000009755 93.0
CMS2_k127_2079744_17 Cupredoxin-like domain K02275 - 1.9.3.1 0.00000000000005969 82.0
CMS2_k127_2079744_18 pyridoxamine 5'-phosphate - - - 0.0000000000005191 76.0
CMS2_k127_2079744_2 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 409.0
CMS2_k127_2079744_20 Protein of unknown function (DUF2798) - - - 0.00005272 48.0
CMS2_k127_2079744_22 Circadian clock protein KaiC - - - 0.00006822 54.0
CMS2_k127_2079744_23 PQQ enzyme repeat - - - 0.0006742 53.0
CMS2_k127_2079744_24 PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.0006867 53.0
CMS2_k127_2079744_3 PFAM beta-lactamase domain protein K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 362.0
CMS2_k127_2079744_4 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 294.0
CMS2_k127_2079744_5 DNA polymerase K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000002622 270.0
CMS2_k127_2079744_6 Flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000008577 224.0
CMS2_k127_2079744_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000001423 198.0
CMS2_k127_2079744_8 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000001905 144.0
CMS2_k127_2079744_9 protein with conserved CXXC pairs - - - 0.0000000000000000000000000000000000605 137.0
CMS2_k127_2109769_0 by modhmm K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 360.0
CMS2_k127_2109769_1 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 331.0
CMS2_k127_2109769_2 S-layer homology domain - - - 0.000000000000000000000000000000000000000000000000000000000258 230.0
CMS2_k127_2109769_3 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000000005368 113.0
CMS2_k127_2109769_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000006059 105.0
CMS2_k127_2109769_5 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000343 96.0
CMS2_k127_2109769_6 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000003716 66.0
CMS2_k127_2109769_7 membrane K09167 - - 0.000000005018 66.0
CMS2_k127_2109769_8 - - - - 0.00000182 56.0
CMS2_k127_2109769_9 GIY-YIG type nucleases (URI domain) - - - 0.00003945 54.0
CMS2_k127_2244855_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 329.0
CMS2_k127_2244855_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000002626 103.0
CMS2_k127_2252350_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 572.0
CMS2_k127_2252350_1 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 511.0
CMS2_k127_2252350_2 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 332.0
CMS2_k127_2252350_3 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000002954 251.0
CMS2_k127_2252350_4 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000005795 155.0
CMS2_k127_2252350_5 - - - - 0.000000294 55.0
CMS2_k127_230777_0 Alpha beta hydrolase K00433 - 1.11.1.10 0.0009923 43.0
CMS2_k127_2332388_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.716e-312 971.0
CMS2_k127_2332388_1 DNA polymerase X family K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 597.0
CMS2_k127_2332388_2 COG0531 Amino acid transporters - - - 0.000000000000000000000000000000000000000000000000000000002399 218.0
CMS2_k127_2332388_3 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000003904 198.0
CMS2_k127_2332388_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000001731 152.0
CMS2_k127_2332388_5 Belongs to the SfsA family K01892,K06206 - 6.1.1.21 0.0000000000000000000000000000001689 127.0
CMS2_k127_2332388_6 - - - - 0.000000000000007534 83.0
CMS2_k127_2332388_7 MFS/sugar transport protein - - - 0.000000000003082 78.0
CMS2_k127_2332388_8 Transcriptional regulator PadR-like family - - - 0.0000000006316 66.0
CMS2_k127_2332388_9 Protein of unknown function (DUF1638) - - - 0.000000005965 65.0
CMS2_k127_2341614_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 462.0
CMS2_k127_2341614_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 350.0
CMS2_k127_2341614_10 Domain of unknown function (DUF296) - - - 0.0000000000000000000000000000000000000000000009283 169.0
CMS2_k127_2341614_11 Transcriptional regulator - - - 0.0000000000000000000000000000001831 133.0
CMS2_k127_2341614_12 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000007618 122.0
CMS2_k127_2341614_13 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000006454 128.0
CMS2_k127_2341614_14 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000003989 109.0
CMS2_k127_2341614_15 TfoX N-terminal domain - - - 0.0000000000000000004907 90.0
CMS2_k127_2341614_16 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 0.000000000000168 82.0
CMS2_k127_2341614_17 PFAM glycosyl transferase family 39 - - - 0.000000004337 69.0
CMS2_k127_2341614_18 Cell division protein - - - 0.000308 49.0
CMS2_k127_2341614_2 Glycosyl Transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 326.0
CMS2_k127_2341614_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 324.0
CMS2_k127_2341614_4 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009136 298.0
CMS2_k127_2341614_5 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001875 274.0
CMS2_k127_2341614_6 Psort location CytoplasmicMembrane, score 10.00 K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000491 256.0
CMS2_k127_2341614_7 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000002811 221.0
CMS2_k127_2341614_8 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000001755 184.0
CMS2_k127_2341614_9 Ribbon-helix-helix protein, copG family - - - 0.0000000000000000000000000000000000000000000000008863 181.0
CMS2_k127_2354752_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 1.056e-293 923.0
CMS2_k127_2354752_1 Transcriptional regulator K03524 - 6.3.4.15 0.00000000000000000000000000000000000002878 153.0
CMS2_k127_2354752_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000005866 135.0
CMS2_k127_2354752_3 YHS domain - - - 0.00000000000000002526 82.0
CMS2_k127_2354752_4 oxidation-reduction process K22418 - 1.1.1.146 0.00001436 49.0
CMS2_k127_2388727_0 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 586.0
CMS2_k127_2388727_1 PFAM Nickel-dependent hydrogenase, large subunit K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 526.0
CMS2_k127_2388727_10 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.000000000000000000000000000007322 131.0
CMS2_k127_2388727_11 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000004094 123.0
CMS2_k127_2388727_12 spore germination K00442,K08315 - 3.4.23.51 0.000000000000000000000002018 108.0
CMS2_k127_2388727_13 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000002993 107.0
CMS2_k127_2388727_14 - - - - 0.0000000000000000002621 89.0
CMS2_k127_2388727_15 NAD(P)H dehydrogenase (quinone) activity K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.000000001638 65.0
CMS2_k127_2388727_16 EamA-like transporter family - - - 0.000000001957 68.0
CMS2_k127_2388727_17 Transglutaminase-like domain - - - 0.0000003542 61.0
CMS2_k127_2388727_18 OsmC-like protein - - - 0.00002196 47.0
CMS2_k127_2388727_19 COG1520 FOG WD40-like repeat - - - 0.0000242 58.0
CMS2_k127_2388727_2 helicase superfamily c-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 455.0
CMS2_k127_2388727_20 - - - - 0.00003176 53.0
CMS2_k127_2388727_21 Belongs to the peptidase M10A family K07761,K07999 GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009753,GO:0010033,GO:0010035,GO:0010038,GO:0016020,GO:0016787,GO:0019538,GO:0031224,GO:0031225,GO:0032502,GO:0040007,GO:0042221,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046686,GO:0048519,GO:0048580,GO:0048583,GO:0048589,GO:0048831,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080186,GO:0140096,GO:1900055,GO:1900056,GO:1901564,GO:1901700,GO:1905622,GO:2000024,GO:2000026,GO:2000028,GO:2000241 - 0.0003273 52.0
CMS2_k127_2388727_3 GTPase of unknown function C-terminal K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 395.0
CMS2_k127_2388727_4 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 312.0
CMS2_k127_2388727_5 Protein of unknown function (DUF790) K09744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 303.0
CMS2_k127_2388727_6 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000003713 253.0
CMS2_k127_2388727_7 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000001458 241.0
CMS2_k127_2388727_8 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000000000000000000001565 225.0
CMS2_k127_2388727_9 GYD domain - - - 0.0000000000000000000000000000000000003655 142.0
CMS2_k127_2409795_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 2.222e-238 755.0
CMS2_k127_2409795_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.329e-233 738.0
CMS2_k127_2409795_10 Zn-dependent protease with chaperone function K03799 - - 0.0000000000000000000000000000000000000000000000000000000000001179 224.0
CMS2_k127_2409795_11 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000003807 204.0
CMS2_k127_2409795_12 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.0000000000000000000000000000000000000000000000000000003202 201.0
CMS2_k127_2409795_13 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000009081 199.0
CMS2_k127_2409795_14 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000001033 175.0
CMS2_k127_2409795_15 PFAM regulatory protein AsnC Lrp family K03718 - - 0.00000000000000000000000000000000000000001271 158.0
CMS2_k127_2409795_16 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.000000000000000000000000000000000004355 151.0
CMS2_k127_2409795_17 transcriptional - - - 0.0000000000000000000000000001367 118.0
CMS2_k127_2409795_18 Peptidase A24B, FlaK domain protein K07991 - 3.4.23.52 0.00000000000000001201 93.0
CMS2_k127_2409795_19 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000001651 79.0
CMS2_k127_2409795_2 PFAM type II secretion system protein E K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 542.0
CMS2_k127_2409795_20 Transcriptional regulator PadR-like family K10947 - - 0.0000000001035 67.0
CMS2_k127_2409795_21 HxlR-like helix-turn-helix - - - 0.000000002 64.0
CMS2_k127_2409795_22 - - - - 0.00000003739 59.0
CMS2_k127_2409795_23 NfeD-like C-terminal, partner-binding K07403 - - 0.0000004364 58.0
CMS2_k127_2409795_24 ferredoxin K05337 - - 0.00001791 49.0
CMS2_k127_2409795_25 - - - - 0.0001062 51.0
CMS2_k127_2409795_3 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 484.0
CMS2_k127_2409795_4 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 453.0
CMS2_k127_2409795_5 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 370.0
CMS2_k127_2409795_6 TIGRFAM geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 350.0
CMS2_k127_2409795_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 312.0
CMS2_k127_2409795_8 PFAM type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 312.0
CMS2_k127_2409795_9 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000006622 241.0
CMS2_k127_2453806_0 PFAM Glycosyl transferase family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000007238 199.0
CMS2_k127_2458250_0 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000000000000000000000000000000000000000000000000000000000000000006914 245.0
CMS2_k127_2458250_1 Radical SAM domain protein K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000002162 202.0
CMS2_k127_2471968_0 Heat shock 70 kDa protein K04043 - - 2.158e-246 776.0
CMS2_k127_2471968_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 410.0
CMS2_k127_2471968_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000008961 113.0
CMS2_k127_2471968_11 COG0328 Ribonuclease HI K03469 - 3.1.26.4 0.0000000000000000000002097 102.0
CMS2_k127_2471968_12 Papain family cysteine protease - - - 0.000000000000000000004756 107.0
CMS2_k127_2471968_13 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000008485 97.0
CMS2_k127_2471968_14 4Fe-4S binding domain protein - - - 0.00000000000001192 83.0
CMS2_k127_2471968_16 - - - - 0.00001049 50.0
CMS2_k127_2471968_17 Right handed beta helix region - - - 0.0003241 53.0
CMS2_k127_2471968_2 Zn-dependent protease with chaperone function K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 404.0
CMS2_k127_2471968_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 390.0
CMS2_k127_2471968_4 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 322.0
CMS2_k127_2471968_5 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001452 280.0
CMS2_k127_2471968_6 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000007373 162.0
CMS2_k127_2471968_7 ASPIC and UnbV - - - 0.000000000000000000000000000000000000003687 168.0
CMS2_k127_2471968_8 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000001251 145.0
CMS2_k127_2471968_9 Peptidase A4 family - - - 0.00000000000000000000000000000000003696 145.0
CMS2_k127_2511657_0 MGS-like domain K01955 - 6.3.5.5 0.0 1203.0
CMS2_k127_2511657_1 aconitate hydratase K01681 - 4.2.1.3 1.7e-262 823.0
CMS2_k127_2511657_10 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 371.0
CMS2_k127_2511657_11 PFAM isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 319.0
CMS2_k127_2511657_12 protein tyrosine kinase activity K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 304.0
CMS2_k127_2511657_13 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 296.0
CMS2_k127_2511657_14 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005875 283.0
CMS2_k127_2511657_15 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K05831 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000958 265.0
CMS2_k127_2511657_16 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000393 248.0
CMS2_k127_2511657_17 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000006522 247.0
CMS2_k127_2511657_18 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000003466 142.0
CMS2_k127_2511657_19 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000008284 141.0
CMS2_k127_2511657_2 Pfam:DUF39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 554.0
CMS2_k127_2511657_20 4Fe-4S binding domain - - - 0.00000000000000000000000000000000411 146.0
CMS2_k127_2511657_21 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000004686 119.0
CMS2_k127_2511657_22 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000004158 100.0
CMS2_k127_2511657_23 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000000000000000000006699 97.0
CMS2_k127_2511657_24 - - - - 0.000000000000000635 85.0
CMS2_k127_2511657_25 PFAM Adenosine specific kinase K09129 - - 0.000000000000002219 76.0
CMS2_k127_2511657_26 lysine biosynthesis protein LysW K05826 - - 0.0000000000002182 73.0
CMS2_k127_2511657_27 Protein of unknown function DUF131 - - - 0.00000003371 58.0
CMS2_k127_2511657_28 Periplasmic copper-binding protein (NosD) - - - 0.0000001353 63.0
CMS2_k127_2511657_29 RimK domain protein ATP-grasp K14940 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0043774,GO:0044424,GO:0044464 6.3.2.32 0.0008911 51.0
CMS2_k127_2511657_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 516.0
CMS2_k127_2511657_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 478.0
CMS2_k127_2511657_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 455.0
CMS2_k127_2511657_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 430.0
CMS2_k127_2511657_7 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 423.0
CMS2_k127_2511657_8 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 377.0
CMS2_k127_2511657_9 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 379.0
CMS2_k127_255122_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 321.0
CMS2_k127_255122_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K03294 - - 0.0000000000000000000000000006295 117.0
CMS2_k127_255122_2 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000001229 116.0
CMS2_k127_255122_3 protein with SCP PR1 domains - - - 0.00000000000000000001348 99.0
CMS2_k127_255122_4 FR47-like protein - - - 0.000000001683 65.0
CMS2_k127_255122_5 - - - - 0.000026 53.0
CMS2_k127_255122_6 COG3842 ABC-type spermidine putrescine transport systems, ATPase components - - - 0.0000395 46.0
CMS2_k127_255922_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K17998,K18331 - 1.12.1.3,1.12.1.4,1.6.5.3 2.298e-199 634.0
CMS2_k127_255922_1 PFAM nickel-dependent hydrogenase, large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 585.0
CMS2_k127_255922_10 vacuolar transport - - - 0.000000000000000001223 96.0
CMS2_k127_255922_11 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000483 76.0
CMS2_k127_255922_12 - - - - 0.000121 52.0
CMS2_k127_255922_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 505.0
CMS2_k127_255922_3 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 450.0
CMS2_k127_255922_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 297.0
CMS2_k127_255922_5 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000009979 268.0
CMS2_k127_255922_6 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K05588 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000134 261.0
CMS2_k127_255922_7 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000002507 210.0
CMS2_k127_255922_8 conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000000000000199 172.0
CMS2_k127_255922_9 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.0000000000000000000000000000000000000000002167 164.0
CMS2_k127_2685302_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 7.574e-201 640.0
CMS2_k127_2685302_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 591.0
CMS2_k127_2685302_10 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000004351 149.0
CMS2_k127_2685302_11 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.00000000000000000000000000000000001457 141.0
CMS2_k127_2685302_12 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000593 134.0
CMS2_k127_2685302_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000000000000000000000004611 130.0
CMS2_k127_2685302_14 ribosomal protein K02976 - - 0.000000000000000000000000000003988 121.0
CMS2_k127_2685302_15 PAC2 family K07159 - - 0.0000000000000000000000000115 117.0
CMS2_k127_2685302_16 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000003122 96.0
CMS2_k127_2685302_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014 - - 0.000000000000000002451 89.0
CMS2_k127_2685302_18 helix_turn_helix ASNC type K03718 - - 0.00000000004575 74.0
CMS2_k127_2685302_19 - - - - 0.00000000009859 69.0
CMS2_k127_2685302_2 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 397.0
CMS2_k127_2685302_20 Methyltransferase domain - - - 0.00000001436 65.0
CMS2_k127_2685302_21 In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha- aminoadipate (AAA) pathway K06154 - - 0.00000001903 66.0
CMS2_k127_2685302_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 367.0
CMS2_k127_2685302_4 Domain of unknown function (DUF4438) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 341.0
CMS2_k127_2685302_5 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 340.0
CMS2_k127_2685302_6 PFAM ATP-NAD AcoX kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 331.0
CMS2_k127_2685302_7 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 302.0
CMS2_k127_2685302_8 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 300.0
CMS2_k127_2685302_9 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000007109 165.0
CMS2_k127_2886212_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000007545 85.0
CMS2_k127_2886212_1 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000329 90.0
CMS2_k127_2886212_2 Transcriptional regulator, TrmB - - - 0.00000004609 59.0
CMS2_k127_2886212_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000001911 61.0
CMS2_k127_3068074_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000003535 207.0
CMS2_k127_3068074_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000002291 128.0
CMS2_k127_3068074_2 Transcriptional regulator K07729 - - 0.00000000000000000000002295 100.0
CMS2_k127_3068074_4 Membrane - - - 0.0006156 49.0
CMS2_k127_3221789_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 2.096e-291 906.0
CMS2_k127_3221789_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.555e-232 738.0
CMS2_k127_3221789_10 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 428.0
CMS2_k127_3221789_11 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 406.0
CMS2_k127_3221789_12 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 400.0
CMS2_k127_3221789_13 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 396.0
CMS2_k127_3221789_14 hydrogenase expression formation protein K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 382.0
CMS2_k127_3221789_15 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 377.0
CMS2_k127_3221789_16 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 357.0
CMS2_k127_3221789_17 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 346.0
CMS2_k127_3221789_18 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 324.0
CMS2_k127_3221789_19 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 317.0
CMS2_k127_3221789_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 2.057e-228 723.0
CMS2_k127_3221789_20 Catalyzes the oxidation of methylene-H(4)MPT to methenyl-H(4)MPT( ) K00319 - 1.5.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 308.0
CMS2_k127_3221789_21 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 308.0
CMS2_k127_3221789_22 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 290.0
CMS2_k127_3221789_23 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 292.0
CMS2_k127_3221789_24 Thioredoxin reductase K00384,K03387 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001749 285.0
CMS2_k127_3221789_25 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004579 282.0
CMS2_k127_3221789_26 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000004498 266.0
CMS2_k127_3221789_27 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000008675 267.0
CMS2_k127_3221789_28 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000502 267.0
CMS2_k127_3221789_29 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000008738 268.0
CMS2_k127_3221789_3 Belongs to the carbamoyltransferase HypF family K04656 - - 4.069e-213 685.0
CMS2_k127_3221789_30 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002407 262.0
CMS2_k127_3221789_31 - K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001867 256.0
CMS2_k127_3221789_32 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000002681 239.0
CMS2_k127_3221789_33 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000686 241.0
CMS2_k127_3221789_34 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000976 231.0
CMS2_k127_3221789_35 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000002543 224.0
CMS2_k127_3221789_36 Domain of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000495 211.0
CMS2_k127_3221789_37 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000006175 204.0
CMS2_k127_3221789_38 Thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000001033 201.0
CMS2_k127_3221789_39 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000002911 195.0
CMS2_k127_3221789_4 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.359e-203 658.0
CMS2_k127_3221789_40 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000044 194.0
CMS2_k127_3221789_41 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000139 198.0
CMS2_k127_3221789_42 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000001614 203.0
CMS2_k127_3221789_43 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000005482 191.0
CMS2_k127_3221789_44 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000002034 183.0
CMS2_k127_3221789_45 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000901 183.0
CMS2_k127_3221789_46 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000002448 174.0
CMS2_k127_3221789_47 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000005569 158.0
CMS2_k127_3221789_48 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000001807 156.0
CMS2_k127_3221789_49 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000001905 155.0
CMS2_k127_3221789_5 Belongs to the RtcB family K14415 GO:0000394,GO:0003674,GO:0003824,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.3 3.029e-196 623.0
CMS2_k127_3221789_50 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000002064 164.0
CMS2_k127_3221789_51 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.000000000000000000000000000000000000003972 147.0
CMS2_k127_3221789_52 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.00000000000000000000000000000000000007116 147.0
CMS2_k127_3221789_53 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000000000000000001308 136.0
CMS2_k127_3221789_54 PUA domain containing protein K07398 - - 0.0000000000000000000000000000000001761 137.0
CMS2_k127_3221789_55 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000000000000002467 136.0
CMS2_k127_3221789_56 AhpC/TSA family K03564 - 1.11.1.15 0.00000000000000000000000000000001391 131.0
CMS2_k127_3221789_57 PFAM coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00441 - 1.12.98.1 0.0000000000000000000000000000001659 140.0
CMS2_k127_3221789_58 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000123 120.0
CMS2_k127_3221789_59 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.0000000000000000000000000001251 117.0
CMS2_k127_3221789_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 613.0
CMS2_k127_3221789_60 PFAM PfkB - - - 0.0000000000000000000000000001301 126.0
CMS2_k127_3221789_61 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000001012 117.0
CMS2_k127_3221789_62 - - - - 0.00000000000000000000000002763 113.0
CMS2_k127_3221789_63 Flavodoxin - - - 0.000000000000000000000001781 109.0
CMS2_k127_3221789_64 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000002946 97.0
CMS2_k127_3221789_65 Helix-turn-helix XRE-family like proteins K03627 - - 0.0000000000000000009999 95.0
CMS2_k127_3221789_66 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000003513 86.0
CMS2_k127_3221789_67 PFAM glutaredoxin - - - 0.00000000000000001974 86.0
CMS2_k127_3221789_68 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000002398 86.0
CMS2_k127_3221789_69 - - - - 0.000000000000005759 76.0
CMS2_k127_3221789_7 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 525.0
CMS2_k127_3221789_70 Protein of unknown function (DUF354) K09726 - - 0.000000000000008189 81.0
CMS2_k127_3221789_71 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000001423 75.0
CMS2_k127_3221789_72 Uncharacterized protein conserved in archaea (DUF2110) - - - 0.00000000000004438 81.0
CMS2_k127_3221789_73 HAD-hyrolase-like K07025 - - 0.00000000000005524 81.0
CMS2_k127_3221789_75 HTH domain - - - 0.00000000000266 76.0
CMS2_k127_3221789_76 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000003297 74.0
CMS2_k127_3221789_77 Belongs to the UPF0235 family K09131 - - 0.00000000002853 67.0
CMS2_k127_3221789_78 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000002897 70.0
CMS2_k127_3221789_79 Protein of unknown function (DUF981) K08980 - - 0.0000001953 60.0
CMS2_k127_3221789_8 flavodoxin nitric oxide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 458.0
CMS2_k127_3221789_80 - - - - 0.0000006529 59.0
CMS2_k127_3221789_81 Mo-molybdopterin cofactor metabolic process - - - 0.000001602 51.0
CMS2_k127_3221789_82 Redoxin K03564 - 1.11.1.15 0.00007211 49.0
CMS2_k127_3221789_84 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0007891 51.0
CMS2_k127_3221789_9 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 456.0
CMS2_k127_3223611_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 5.479e-221 700.0
CMS2_k127_3223611_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 426.0
CMS2_k127_3223611_10 COG0455 ATPases involved in chromosome partitioning K03496,K03609 - - 0.00000000000000000000000000000000000000000003296 171.0
CMS2_k127_3223611_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000003087 148.0
CMS2_k127_3223611_12 LysE type translocator - - - 0.00000000000000000000000000000000005295 142.0
CMS2_k127_3223611_13 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000002876 134.0
CMS2_k127_3223611_15 nitrite reductase [NAD(P)H] activity K00363,K05710 - 1.7.1.15 0.0000000000000000000004294 99.0
CMS2_k127_3223611_16 Transcriptional regulator, TrmB - - - 0.00000000000000001153 88.0
CMS2_k127_3223611_17 - - - - 0.000000000000005288 83.0
CMS2_k127_3223611_18 A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products K03552 - 3.1.22.4 0.000002187 55.0
CMS2_k127_3223611_19 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0008782 53.0
CMS2_k127_3223611_2 DeoC/LacD family aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 380.0
CMS2_k127_3223611_3 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 385.0
CMS2_k127_3223611_4 DNA primase K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 355.0
CMS2_k127_3223611_5 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 317.0
CMS2_k127_3223611_6 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000007383 216.0
CMS2_k127_3223611_7 Nicotinamidase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000001725 216.0
CMS2_k127_3223611_8 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000006832 186.0
CMS2_k127_3223611_9 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000000000003397 169.0
CMS2_k127_3232484_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.25e-276 880.0
CMS2_k127_3232484_1 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 430.0
CMS2_k127_3232484_2 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.0000000000000000000000000000000000000000000000000000002504 203.0
CMS2_k127_3232484_5 Belongs to the FPP GGPP synthase family K13787 GO:0000287,GO:0003674,GO:0003824,GO:0004161,GO:0004659,GO:0005488,GO:0005506,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0030145,GO:0033383,GO:0033384,GO:0033385,GO:0033386,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045337,GO:0045338,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000001673 72.0
CMS2_k127_3232484_6 ORF located using Blastx - - - 0.0000000001848 63.0
CMS2_k127_3232484_7 - - - - 0.000000006659 66.0
CMS2_k127_3232484_8 Bacteriochlorophyll chlorophyll K04040 - 2.5.1.133,2.5.1.62 0.00009404 53.0
CMS2_k127_3232484_9 Phage integrase family - - - 0.0003711 53.0
CMS2_k127_3242401_0 Ferrous iron transport protein B K04759 - - 4.19e-262 824.0
CMS2_k127_3242401_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 613.0
CMS2_k127_3242401_10 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000003255 243.0
CMS2_k127_3242401_11 Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000005806 197.0
CMS2_k127_3242401_12 Ser thr protein kinase K07176 - - 0.000000000000000000000000000000000000000000000000000012 198.0
CMS2_k127_3242401_13 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000008599 163.0
CMS2_k127_3242401_14 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000003892 150.0
CMS2_k127_3242401_15 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000001094 141.0
CMS2_k127_3242401_16 PFAM sodium calcium exchanger K07301 - - 0.0000000000000000000000000000000001879 145.0
CMS2_k127_3242401_17 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000001109 140.0
CMS2_k127_3242401_18 - - - - 0.0000000000000000001495 93.0
CMS2_k127_3242401_19 TIGRFAM TIGR04076 family protein - - - 0.0000000000000000001846 91.0
CMS2_k127_3242401_2 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 577.0
CMS2_k127_3242401_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000003962 78.0
CMS2_k127_3242401_21 OsmC-like protein - - - 0.0000001337 59.0
CMS2_k127_3242401_22 regulatory protein, arsR - - - 0.00005963 48.0
CMS2_k127_3242401_3 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 566.0
CMS2_k127_3242401_4 Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0008964,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0071704 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 510.0
CMS2_k127_3242401_5 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 400.0
CMS2_k127_3242401_6 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 373.0
CMS2_k127_3242401_7 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 361.0
CMS2_k127_3242401_8 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 304.0
CMS2_k127_3242401_9 Iron dependent K03709 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 287.0
CMS2_k127_3273898_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 6.698e-281 876.0
CMS2_k127_3273898_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 5.841e-254 801.0
CMS2_k127_3273898_10 Belongs to the class-I aminoacyl-tRNA synthetase family K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 415.0
CMS2_k127_3273898_11 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 368.0
CMS2_k127_3273898_12 methylthiotransferase activity K15865 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 353.0
CMS2_k127_3273898_13 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 349.0
CMS2_k127_3273898_14 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 340.0
CMS2_k127_3273898_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 323.0
CMS2_k127_3273898_16 Fumarate hydratase K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 302.0
CMS2_k127_3273898_17 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001981 276.0
CMS2_k127_3273898_18 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006476 263.0
CMS2_k127_3273898_19 GPR1/FUN34/yaaH family K07034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006606 247.0
CMS2_k127_3273898_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.888e-238 764.0
CMS2_k127_3273898_20 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001685 235.0
CMS2_k127_3273898_21 Fe-S type, tartrate fumarate subfamily, beta K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000002543 231.0
CMS2_k127_3273898_22 -acetyltransferase K00657 - 2.3.1.57 0.000000000000000000000000000000000000000000000000000000000000007567 220.0
CMS2_k127_3273898_23 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000003636 226.0
CMS2_k127_3273898_24 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000002715 216.0
CMS2_k127_3273898_25 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000006956 212.0
CMS2_k127_3273898_26 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000002748 191.0
CMS2_k127_3273898_28 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000005661 151.0
CMS2_k127_3273898_29 membrane K07507 - - 0.0000000000000000000000000000000000000488 147.0
CMS2_k127_3273898_3 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 3.632e-217 679.0
CMS2_k127_3273898_30 V-type ATPase 116kDa subunit family K02123 - - 0.00000000000000000000000000000000008023 153.0
CMS2_k127_3273898_31 - - - - 0.00000000000000000000000000001094 127.0
CMS2_k127_3273898_32 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000003649 130.0
CMS2_k127_3273898_33 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000344 92.0
CMS2_k127_3273898_34 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000002538 97.0
CMS2_k127_3273898_35 double-strand break repair via homologous recombination K12614 GO:0000228,GO:0000722,GO:0000723,GO:0000724,GO:0000725,GO:0000781,GO:0000793,GO:0000794,GO:0000803,GO:0001674,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007059,GO:0007568,GO:0007569,GO:0008094,GO:0008150,GO:0008152,GO:0009410,GO:0009987,GO:0010033,GO:0010243,GO:0014070,GO:0014074,GO:0016043,GO:0016462,GO:0016604,GO:0016605,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019899,GO:0022402,GO:0030915,GO:0031000,GO:0031625,GO:0031974,GO:0031981,GO:0032200,GO:0032502,GO:0032991,GO:0033554,GO:0033676,GO:0034641,GO:0035061,GO:0035861,GO:0036270,GO:0042221,GO:0042493,GO:0042585,GO:0042592,GO:0042623,GO:0043073,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043279,GO:0044237,GO:0044238,GO:0044260,GO:0044389,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048518,GO:0048522,GO:0048869,GO:0050000,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051276,GO:0051304,GO:0051640,GO:0051641,GO:0051716,GO:0051983,GO:0051984,GO:0060249,GO:0065007,GO:0065008,GO:0070013,GO:0071139,GO:0071704,GO:0071840,GO:0090304,GO:0090398,GO:0090734,GO:0097159,GO:0097240,GO:0098687,GO:0106068,GO:1901360,GO:1901363,GO:1901698,GO:1902494,GO:1990234,GO:1990683 3.6.4.13 0.0000000000000004068 93.0
CMS2_k127_3273898_36 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000001058 85.0
CMS2_k127_3273898_37 to Saccharomyces cerevisiae SMC5 (YOL034W) - GO:0000166,GO:0000725,GO:0000793,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0007059,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022402,GO:0030554,GO:0030915,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051304,GO:0051716,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0106068,GO:1901265,GO:1901360,GO:1901363,GO:1902494,GO:1990234 - 0.000000000000003774 89.0
CMS2_k127_3273898_38 Transcriptional regulator K07108 - - 0.00000000000004975 76.0
CMS2_k127_3273898_39 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000154 76.0
CMS2_k127_3273898_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 7.106e-209 665.0
CMS2_k127_3273898_40 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000000005181 59.0
CMS2_k127_3273898_41 - - - - 0.0000001142 59.0
CMS2_k127_3273898_42 PFAM SNARE associated Golgi protein - - - 0.00001554 54.0
CMS2_k127_3273898_43 ATP synthase K02122 - - 0.0002451 48.0
CMS2_k127_3273898_44 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.0005426 49.0
CMS2_k127_3273898_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 607.0
CMS2_k127_3273898_6 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 526.0
CMS2_k127_3273898_7 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 455.0
CMS2_k127_3273898_8 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 438.0
CMS2_k127_3273898_9 heavy metal-(Cd Co Hg Pb Zn)-translocating K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 434.0
CMS2_k127_3316580_0 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 422.0
CMS2_k127_3316580_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 389.0
CMS2_k127_3316580_10 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000001798 194.0
CMS2_k127_3316580_11 F420-0:Gamma-glutamyl ligase - - - 0.000000000000000000000000000000000000000001289 167.0
CMS2_k127_3316580_12 belongs to the PRA-CH family K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000005759 150.0
CMS2_k127_3316580_13 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000007621 152.0
CMS2_k127_3316580_14 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000009077 135.0
CMS2_k127_3316580_15 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000004066 94.0
CMS2_k127_3316580_16 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000128 64.0
CMS2_k127_3316580_17 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00005131 46.0
CMS2_k127_3316580_18 - - - - 0.0005545 53.0
CMS2_k127_3316580_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 355.0
CMS2_k127_3316580_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 331.0
CMS2_k127_3316580_4 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 323.0
CMS2_k127_3316580_5 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003955 265.0
CMS2_k127_3316580_6 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000005334 245.0
CMS2_k127_3316580_7 Diphthamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001495 236.0
CMS2_k127_3316580_8 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000002366 207.0
CMS2_k127_3316580_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000001233 202.0
CMS2_k127_3317874_0 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 377.0
CMS2_k127_3317874_1 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 355.0
CMS2_k127_3317874_10 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000004257 153.0
CMS2_k127_3317874_11 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000001012 149.0
CMS2_k127_3317874_12 - K01633,K07144 - 1.13.11.81,2.7.4.31,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000002188 147.0
CMS2_k127_3317874_13 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000007137 132.0
CMS2_k127_3317874_14 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000006204 105.0
CMS2_k127_3317874_15 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000001068 90.0
CMS2_k127_3317874_16 Transcriptional regulator K07775 - - 0.00000000006023 67.0
CMS2_k127_3317874_17 Mn2 dependent serine threonine protein kinase - - - 0.000000001411 71.0
CMS2_k127_3317874_18 Belongs to the thioredoxin family K03671 - - 0.00009641 49.0
CMS2_k127_3317874_19 Dehydrogenase K00114 - 1.1.2.8 0.0008618 53.0
CMS2_k127_3317874_2 UV-endonuclease UvdE K13281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 334.0
CMS2_k127_3317874_3 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003603 279.0
CMS2_k127_3317874_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001339 283.0
CMS2_k127_3317874_5 TIGRFAM SagB-type dehydrogenase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001915 260.0
CMS2_k127_3317874_6 H4MPT-linked C1 transfer pathway protein K07072 - 2.5.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000002711 265.0
CMS2_k127_3317874_7 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000001627 214.0
CMS2_k127_3317874_8 Pfam ATP-grasp domain K06914 - 6.3.4.24 0.00000000000000000000000000000000000000000000626 179.0
CMS2_k127_3317874_9 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000004582 161.0
CMS2_k127_3319455_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000042 250.0
CMS2_k127_3319455_1 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.0000000000000000000000000005952 127.0
CMS2_k127_3319455_3 acetyltransferase - - - 0.000002144 56.0
CMS2_k127_3321180_0 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004049 278.0
CMS2_k127_3321180_1 cellulase activity K20276 - - 0.00000000000000000000000000000000000000000000000007247 193.0
CMS2_k127_3465784_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 454.0
CMS2_k127_3465784_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 448.0
CMS2_k127_3465784_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 428.0
CMS2_k127_3465784_3 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 308.0
CMS2_k127_3465784_4 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000002127 199.0
CMS2_k127_3465784_5 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.0000000000000000006893 89.0
CMS2_k127_3465784_6 Transcriptional regulator K07108 - - 0.0000004443 56.0
CMS2_k127_3465784_7 Protein of unknown function (DUF2400) - - - 0.0001362 54.0
CMS2_k127_3465784_8 XK-related protein 5 - - - 0.0002445 46.0
CMS2_k127_3556933_0 - - - - 0.00000000001454 72.0
CMS2_k127_3570969_0 Beta-Casp domain K07041 - - 4.063e-212 676.0
CMS2_k127_3570969_1 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 541.0
CMS2_k127_3570969_10 ABC 3 transport family K19976 - - 0.00000000000000000000000000000448 129.0
CMS2_k127_3570969_11 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000003894 116.0
CMS2_k127_3570969_12 response regulator, receiver K07669 - - 0.00000000000000000000001696 104.0
CMS2_k127_3570969_13 RNA polymerase subunit 9 K03057 - - 0.00000000000000000000005592 102.0
CMS2_k127_3570969_14 Pfam:DUF552 K09152 - - 0.000000000000000000001215 98.0
CMS2_k127_3570969_15 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.000000000000000002977 89.0
CMS2_k127_3570969_16 EamA-like transporter family - - - 0.00000000000439 76.0
CMS2_k127_3570969_17 PFAM CBS domain containing protein - - - 0.00000001255 68.0
CMS2_k127_3570969_2 Phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 415.0
CMS2_k127_3570969_3 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008478 321.0
CMS2_k127_3570969_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 296.0
CMS2_k127_3570969_5 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001511 255.0
CMS2_k127_3570969_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000002207 232.0
CMS2_k127_3570969_7 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001119 220.0
CMS2_k127_3570969_8 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000006998 205.0
CMS2_k127_3570969_9 ATPases associated with a variety of cellular activities K09817 - - 0.00000000000000000000000000000000000000000000000002892 186.0
CMS2_k127_3581601_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 348.0
CMS2_k127_3581601_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004215 271.0
CMS2_k127_3581601_10 4Fe-4S ferredoxin iron-sulfur binding domain K18979 - 1.17.99.6 0.0000000000000000000000000000000002241 141.0
CMS2_k127_3581601_11 Phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000006991 134.0
CMS2_k127_3581601_12 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000239 125.0
CMS2_k127_3581601_13 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.00000000000000000004448 107.0
CMS2_k127_3581601_14 Domain of unknown function (DUF1508) K09946 - - 0.000000000000000001199 96.0
CMS2_k127_3581601_15 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000001584 87.0
CMS2_k127_3581601_16 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000002226 80.0
CMS2_k127_3581601_17 Mechanosensitive ion channel - - - 0.000000000000002388 77.0
CMS2_k127_3581601_18 Transcriptional regulator PadR-like family - - - 0.0000000000004035 77.0
CMS2_k127_3581601_2 Glutamine cyclotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001199 272.0
CMS2_k127_3581601_3 SMART zinc finger, CDGSH-type domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004496 265.0
CMS2_k127_3581601_4 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000002535 228.0
CMS2_k127_3581601_5 ABC transporter, ATP-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000002061 226.0
CMS2_k127_3581601_6 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000001785 210.0
CMS2_k127_3581601_7 metallo-beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000006282 199.0
CMS2_k127_3581601_8 pfam abc K02003 - - 0.000000000000000000000000000000000000000000000000005764 202.0
CMS2_k127_3581601_9 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000003079 161.0
CMS2_k127_3675521_0 COG0517 FOG CBS domain - - - 0.0000000000000000000000000000001014 132.0
CMS2_k127_3675521_1 Starch synthase catalytic domain - - - 0.000000000000000000004241 94.0
CMS2_k127_3675521_2 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000418 53.0
CMS2_k127_3675521_3 Glycosyl transferase 4-like domain - - - 0.00085 45.0
CMS2_k127_3675542_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 5.68e-281 877.0
CMS2_k127_376508_0 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 3.313e-196 630.0
CMS2_k127_376508_1 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 374.0
CMS2_k127_376508_10 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000001883 134.0
CMS2_k127_376508_11 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000002235 106.0
CMS2_k127_376508_12 exosome subunit K07581 - - 0.000000000000000001553 91.0
CMS2_k127_376508_13 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000003218 87.0
CMS2_k127_376508_14 HTH DNA binding domain K06930 - - 0.000000000000000345 86.0
CMS2_k127_376508_15 snRNP Sm proteins K04796 - - 0.0000000000000859 74.0
CMS2_k127_376508_16 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000003042 71.0
CMS2_k127_376508_17 - - - - 0.00000001839 64.0
CMS2_k127_376508_18 Putative zinc- or iron-chelating domain K06940 - - 0.00000003136 61.0
CMS2_k127_376508_19 Belongs to the eukaryotic ribosomal protein eL13 family K02873 - - 0.0000001336 57.0
CMS2_k127_376508_2 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 346.0
CMS2_k127_376508_20 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.000001624 58.0
CMS2_k127_376508_21 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.000007211 52.0
CMS2_k127_376508_3 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 323.0
CMS2_k127_376508_4 RIO-like serine threonine protein kinase fused to N-terminal HTH domain K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005046 280.0
CMS2_k127_376508_5 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002688 270.0
CMS2_k127_376508_6 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000004116 247.0
CMS2_k127_376508_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000003094 190.0
CMS2_k127_376508_8 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000000000001007 169.0
CMS2_k127_376508_9 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000009249 145.0
CMS2_k127_398902_0 PFAM aminotransferase, class I K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 382.0
CMS2_k127_398902_1 Haloacid dehalogenase-like hydrolase - - - 0.000000002832 63.0
CMS2_k127_4030486_0 Protein of unknown function (DUF1698) - - - 0.00000000000000000000000000000000000000001857 158.0
CMS2_k127_40654_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1177.0
CMS2_k127_40654_1 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000000000000000000000000000003607 243.0
CMS2_k127_40654_10 rhodopsin K04643 - - 0.00000000309 66.0
CMS2_k127_40654_11 - - - - 0.0000008154 56.0
CMS2_k127_40654_2 - - - - 0.000000000000000000000000000000000000000000000000000000001934 207.0
CMS2_k127_40654_3 COGs COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.00000000000000000000000000000000000000000000000000000001156 201.0
CMS2_k127_40654_4 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000001244 203.0
CMS2_k127_40654_5 - - - - 0.000000000000000000000000000000000000000000000000001231 194.0
CMS2_k127_40654_6 Alpha-ribazole transporter - - - 0.00000000000000000000000000114 119.0
CMS2_k127_40654_7 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000002442 119.0
CMS2_k127_40654_8 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000004727 98.0
CMS2_k127_40654_9 Transcriptional regulator - - - 0.00000000008278 70.0
CMS2_k127_4176154_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 1.651e-287 899.0
CMS2_k127_4176154_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 560.0
CMS2_k127_4176154_10 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000009288 232.0
CMS2_k127_4176154_11 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000008986 225.0
CMS2_k127_4176154_12 Ribose-5-phosphate isomerase. Source PGD - - - 0.00000000000000000000000000000000000000000000000000000000000002209 222.0
CMS2_k127_4176154_13 PFAM Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000002304 209.0
CMS2_k127_4176154_14 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000003021 209.0
CMS2_k127_4176154_15 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000006231 202.0
CMS2_k127_4176154_16 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000003926 198.0
CMS2_k127_4176154_17 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.00000000000000000000000000000000000000000000000001213 184.0
CMS2_k127_4176154_18 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000001143 171.0
CMS2_k127_4176154_19 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000003352 168.0
CMS2_k127_4176154_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 398.0
CMS2_k127_4176154_20 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.00000000000000000000000000000000000000005329 154.0
CMS2_k127_4176154_21 Domain of unknown function (DUF371) K09738 - - 0.000000000000000000000000000001479 125.0
CMS2_k127_4176154_22 COG1522 Transcriptional regulators - - - 0.00000000000000000000000001748 113.0
CMS2_k127_4176154_23 PFAM Glycosyltransferase 28 domain - - - 0.00000000000000000000000007435 120.0
CMS2_k127_4176154_24 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000002742 102.0
CMS2_k127_4176154_25 Domain of unknown function (DUF1610) K07580 - - 0.000000000000004033 79.0
CMS2_k127_4176154_26 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0000000000005788 69.0
CMS2_k127_4176154_27 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000008229 68.0
CMS2_k127_4176154_28 - - - - 0.0000000000562 70.0
CMS2_k127_4176154_29 Signal peptidase K13280 - 3.4.21.89 0.00001161 55.0
CMS2_k127_4176154_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 377.0
CMS2_k127_4176154_30 - - - - 0.0000639 48.0
CMS2_k127_4176154_4 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004327 281.0
CMS2_k127_4176154_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001346 274.0
CMS2_k127_4176154_6 PFAM S-layer - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001641 263.0
CMS2_k127_4176154_7 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000005862 255.0
CMS2_k127_4176154_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000001188 248.0
CMS2_k127_4176154_9 Methyltransferase K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000001946 248.0
CMS2_k127_4178987_0 Belongs to the UPF0337 (CsbD) family - - - 0.0001018 47.0
CMS2_k127_4261638_0 Belongs to the TPP enzyme family K01568,K04103 - 4.1.1.1,4.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000162 247.0
CMS2_k127_4261638_1 endo-1,4-beta-xylanase activity K21636 - 1.1.98.6 0.000000000001153 80.0
CMS2_k127_4261638_2 - - - - 0.00000000001226 77.0
CMS2_k127_4261638_3 Collagen triple helix repeat - - - 0.00000000004248 67.0
CMS2_k127_4261638_4 - - - - 0.000000001902 70.0
CMS2_k127_4261638_5 Transcriptional regulator - - - 0.0000001577 63.0
CMS2_k127_427078_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.0 1062.0
CMS2_k127_427078_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 4.103e-279 879.0
CMS2_k127_427078_10 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 423.0
CMS2_k127_427078_11 PFAM peptidase U62 modulator of DNA gyrase K03568 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0016787,GO:0019538,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 412.0
CMS2_k127_427078_12 phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 406.0
CMS2_k127_427078_13 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 400.0
CMS2_k127_427078_14 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 401.0
CMS2_k127_427078_15 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 391.0
CMS2_k127_427078_16 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 389.0
CMS2_k127_427078_17 PFAM Glycosyl transferase, group 1 K16150 - 2.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 382.0
CMS2_k127_427078_18 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 339.0
CMS2_k127_427078_19 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 326.0
CMS2_k127_427078_2 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 4.794e-247 790.0
CMS2_k127_427078_20 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 315.0
CMS2_k127_427078_21 Glutamate-cysteine ligase family 2(GCS2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 316.0
CMS2_k127_427078_22 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 309.0
CMS2_k127_427078_23 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 302.0
CMS2_k127_427078_24 RimK-like ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 289.0
CMS2_k127_427078_25 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008005 273.0
CMS2_k127_427078_26 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003308 281.0
CMS2_k127_427078_27 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000001587 244.0
CMS2_k127_427078_28 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000001094 239.0
CMS2_k127_427078_29 COG1520 FOG WD40-like repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000002446 254.0
CMS2_k127_427078_3 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 9.512e-195 617.0
CMS2_k127_427078_30 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000000000000000000000000000000003042 207.0
CMS2_k127_427078_31 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000003236 203.0
CMS2_k127_427078_32 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000001172 178.0
CMS2_k127_427078_33 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000002754 170.0
CMS2_k127_427078_34 Archaeal transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000002093 168.0
CMS2_k127_427078_35 RimK-like ATPgrasp N-terminal domain - - - 0.000000000000000000000000000000000001425 147.0
CMS2_k127_427078_36 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000002241 141.0
CMS2_k127_427078_37 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000007399 137.0
CMS2_k127_427078_38 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000000000000000000004309 119.0
CMS2_k127_427078_39 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.00000000000000000000000001383 110.0
CMS2_k127_427078_4 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 539.0
CMS2_k127_427078_40 PFAM Glycosyl transferase, group 1 K16150 - 2.4.1.11 0.00000000000000000000002371 107.0
CMS2_k127_427078_41 Cyclophilin-like K09143 - - 0.00000000000000000000004279 103.0
CMS2_k127_427078_42 PFAM SNARE associated Golgi protein - - - 0.00000000000000000003414 99.0
CMS2_k127_427078_43 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000432 91.0
CMS2_k127_427078_44 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit K00441 - 1.12.98.1 0.0000000000000002156 93.0
CMS2_k127_427078_45 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000001671 80.0
CMS2_k127_427078_46 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.00000000000001117 76.0
CMS2_k127_427078_47 RNA-binding protein involved in rRNA processing K07569 - - 0.00000000000008181 74.0
CMS2_k127_427078_48 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000002354 65.0
CMS2_k127_427078_49 Belongs to the eukaryotic ribosomal protein eS17 family K02962 - - 0.00000000004284 65.0
CMS2_k127_427078_5 4Fe-4S single cluster domain K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 536.0
CMS2_k127_427078_50 Methionine biosynthesis protein MetW K16215 - 2.1.1.243 0.0000000001016 72.0
CMS2_k127_427078_51 TIGRFAM MoaD family protein K03636 - - 0.0000000002574 64.0
CMS2_k127_427078_52 S25 ribosomal protein K02975 - - 0.0000000006938 64.0
CMS2_k127_427078_53 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.000000005042 64.0
CMS2_k127_427078_54 cytochrome-c peroxidase activity K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000008271 63.0
CMS2_k127_427078_56 PQQ-like domain - - - 0.0004392 53.0
CMS2_k127_427078_6 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 463.0
CMS2_k127_427078_7 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 475.0
CMS2_k127_427078_8 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 444.0
CMS2_k127_427078_9 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 429.0
CMS2_k127_4419309_0 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006995 276.0
CMS2_k127_4419309_1 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000005499 138.0
CMS2_k127_4419309_2 signal transduction protein with CBS domains - - - 0.000000000000000000155 98.0
CMS2_k127_4419309_3 PFAM CBS domain containing protein - - - 0.00000000000004208 78.0
CMS2_k127_4419309_4 Signal transduction protein with CBS domains - - - 0.0000000001132 72.0
CMS2_k127_4419309_5 - - - - 0.0000000005671 68.0
CMS2_k127_4419309_6 Cytochrome C assembly protein - - - 0.0000000008663 64.0
CMS2_k127_4436325_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004908 283.0
CMS2_k127_4436325_1 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000000000001863 82.0
CMS2_k127_4443880_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 543.0
CMS2_k127_4443880_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 466.0
CMS2_k127_4443880_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002335 203.0
CMS2_k127_4443880_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000006018 200.0
CMS2_k127_4443880_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000009743 179.0
CMS2_k127_4443880_13 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000004643 174.0
CMS2_k127_4443880_14 PFAM ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000002571 166.0
CMS2_k127_4443880_15 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000003646 163.0
CMS2_k127_4443880_16 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000002438 151.0
CMS2_k127_4443880_17 Binds to the 23S rRNA K02885 - - 0.000000000000000000000000000000000005158 141.0
CMS2_k127_4443880_18 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000001939 137.0
CMS2_k127_4443880_19 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000008528 144.0
CMS2_k127_4443880_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 402.0
CMS2_k127_4443880_20 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000002132 133.0
CMS2_k127_4443880_21 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000003649 130.0
CMS2_k127_4443880_22 Binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001079 107.0
CMS2_k127_4443880_23 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.00000000000000000003323 93.0
CMS2_k127_4443880_24 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.0000000000000000009166 86.0
CMS2_k127_4443880_25 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000002893 66.0
CMS2_k127_4443880_26 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000009938 63.0
CMS2_k127_4443880_3 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 373.0
CMS2_k127_4443880_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 338.0
CMS2_k127_4443880_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 307.0
CMS2_k127_4443880_6 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007083 265.0
CMS2_k127_4443880_7 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000002113 237.0
CMS2_k127_4443880_8 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000003694 229.0
CMS2_k127_4443880_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001372 205.0
CMS2_k127_449621_0 NADH:flavin oxidoreductase / NADH oxidase family K00354 - 1.6.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001546 273.0
CMS2_k127_449621_1 - - - - 0.00000000000000000000000000000000001386 155.0
CMS2_k127_449621_2 Glycosyl hydrolases family 39 - - - 0.000006795 59.0
CMS2_k127_4571475_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002247 234.0
CMS2_k127_4571475_1 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000008277 130.0
CMS2_k127_4571475_2 Methyltransferase domain - - - 0.0000000000000000000000000001182 122.0
CMS2_k127_4571475_3 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000004253 119.0
CMS2_k127_4571475_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000003509 87.0
CMS2_k127_4571475_5 Domain of unknown function (DU1801) - - - 0.00001029 52.0
CMS2_k127_4571475_6 deoxyhypusine monooxygenase activity - - - 0.00001306 51.0
CMS2_k127_4721995_0 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 485.0
CMS2_k127_4721995_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 352.0
CMS2_k127_4721995_10 Glycosyl transferase family group 2 K19003 - 2.4.1.336 0.0000000000000000000000000000003265 139.0
CMS2_k127_4721995_11 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000001235 123.0
CMS2_k127_4721995_12 - - - - 0.000000000000000000000000001248 115.0
CMS2_k127_4721995_13 Flavodoxin - - - 0.00000000000000000000000009841 112.0
CMS2_k127_4721995_14 phospholipid phosphatase K19302 - 3.6.1.27 0.0000000000000000001101 97.0
CMS2_k127_4721995_15 - - - - 0.00000000000000001755 83.0
CMS2_k127_4721995_16 GrpB protein - - - 0.0000000001388 64.0
CMS2_k127_4721995_17 lysine biosynthesis protein LysW K05826 - - 0.000000004402 59.0
CMS2_k127_4721995_18 COG1522 Transcriptional regulators - - - 0.0000008214 53.0
CMS2_k127_4721995_19 FMN binding - - - 0.000001098 57.0
CMS2_k127_4721995_2 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002823 293.0
CMS2_k127_4721995_20 GYD domain - - - 0.000008518 51.0
CMS2_k127_4721995_21 Belongs to the peptidase M16 family K07263 - - 0.00001884 48.0
CMS2_k127_4721995_22 Pyrrolo-quinoline quinone - - - 0.0001241 55.0
CMS2_k127_4721995_23 PKD domain containing protein K17713 - - 0.000279 54.0
CMS2_k127_4721995_24 RDD family - - - 0.000455 49.0
CMS2_k127_4721995_3 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009203 262.0
CMS2_k127_4721995_4 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005167 263.0
CMS2_k127_4721995_5 deoxyribonuclease I - - - 0.00000000000000000000000000000000000000000000000000000000001753 217.0
CMS2_k127_4721995_6 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000001157 172.0
CMS2_k127_4721995_7 lyase activity - - - 0.0000000000000000000000000000000000000000001169 167.0
CMS2_k127_4721995_8 Staygreen protein K22013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006787,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009536,GO:0009579,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010271,GO:0015994,GO:0015996,GO:0016020,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031976,GO:0031984,GO:0033013,GO:0033015,GO:0034357,GO:0034641,GO:0042440,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044270,GO:0044422,GO:0044424,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046149,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051187,GO:0051193,GO:0051195,GO:0055035,GO:0065007,GO:0071704,GO:0090056,GO:1901360,GO:1901361,GO:1901401,GO:1901402,GO:1901404,GO:1901405,GO:1901564,GO:1901565,GO:1901575,GO:1903647 4.99.1.10 0.000000000000000000000000000000000000000006871 158.0
CMS2_k127_4721995_9 Acyltransferase family - - - 0.0000000000000000000000000000000000000102 158.0
CMS2_k127_4868125_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.472e-265 839.0
CMS2_k127_4868125_1 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP-binding K00158 - 1.2.3.3 1.96e-251 788.0
CMS2_k127_4868125_2 Spore germination protein K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004516 274.0
CMS2_k127_4868125_3 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.0000000000000000000000000000000000000000000000000000001111 203.0
CMS2_k127_4868125_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.0000000000000000000000000000000000000000000345 172.0
CMS2_k127_4868125_5 DEAD H associated K03724 - - 0.0000000000000000000000000000000000000000001244 173.0
CMS2_k127_4868125_6 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000003339 155.0
CMS2_k127_4868125_7 Mycolic acid cyclopropane synthetase - - - 0.000000000000749 76.0
CMS2_k127_4868125_8 transcriptional - - - 0.0000003092 61.0
CMS2_k127_4982327_0 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 4.931e-295 932.0
CMS2_k127_4982327_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000005377 164.0
CMS2_k127_4982327_2 4Fe-4S binding domain protein - - - 0.000000000000000000004899 104.0
CMS2_k127_4982327_3 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.0000000000006607 71.0
CMS2_k127_4982327_4 PhoD-like phosphatase - - - 0.000000242 64.0
CMS2_k127_4982327_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000004527 60.0
CMS2_k127_4982327_6 Transcriptional regulator, TrmB - - - 0.00003329 51.0
CMS2_k127_511117_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 559.0
CMS2_k127_511117_1 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 394.0
CMS2_k127_511117_10 DNA polymerase beta domain protein region K07073 - - 0.0000000000000000000000000000000000000000000000000000000008236 209.0
CMS2_k127_511117_11 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000008366 190.0
CMS2_k127_511117_12 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000605 139.0
CMS2_k127_511117_13 Protein of unknown function (DUF996) - - - 0.0000000000000000000000245 107.0
CMS2_k127_511117_14 Transcriptional regulator PadR-like family - - - 0.000000000005369 71.0
CMS2_k127_511117_15 PFAM regulatory protein AsnC Lrp family - - - 0.00000000002853 69.0
CMS2_k127_511117_16 transcriptional regulator, PadR family K10947 - - 0.00000009256 58.0
CMS2_k127_511117_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 376.0
CMS2_k127_511117_3 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 364.0
CMS2_k127_511117_4 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 332.0
CMS2_k127_511117_5 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 314.0
CMS2_k127_511117_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003776 260.0
CMS2_k127_511117_7 PP-loop family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001438 258.0
CMS2_k127_511117_8 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000006355 226.0
CMS2_k127_511117_9 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000148 229.0
CMS2_k127_5133965_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 9.155e-243 773.0
CMS2_k127_5133965_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 600.0
CMS2_k127_5133965_10 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 324.0
CMS2_k127_5133965_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 316.0
CMS2_k127_5133965_12 Protein of unknown function (DUF2961) K14109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 312.0
CMS2_k127_5133965_13 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009767 306.0
CMS2_k127_5133965_14 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 288.0
CMS2_k127_5133965_15 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000002276 267.0
CMS2_k127_5133965_16 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000004537 235.0
CMS2_k127_5133965_17 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000002074 219.0
CMS2_k127_5133965_18 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000002988 213.0
CMS2_k127_5133965_19 Suf system fes assembly protein K04488,K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000005555 197.0
CMS2_k127_5133965_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 482.0
CMS2_k127_5133965_20 Belongs to the anaerobic coproporphyrinogen-III oxidase family K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.00000000000000000000000000000000000000000000000000001576 205.0
CMS2_k127_5133965_21 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000003755 188.0
CMS2_k127_5133965_22 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000002724 181.0
CMS2_k127_5133965_23 by modhmm K03655 - 3.6.4.12 0.000000000000000000000000000000000000007906 167.0
CMS2_k127_5133965_24 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000000000000000000000000000003875 148.0
CMS2_k127_5133965_25 - - - - 0.00000000000000000000000000001337 132.0
CMS2_k127_5133965_26 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000157 111.0
CMS2_k127_5133965_27 Transcription elongation factor - - - 0.00000000000000000001952 98.0
CMS2_k127_5133965_28 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000002862 92.0
CMS2_k127_5133965_29 cobalamin binding - - - 0.000000000000001597 81.0
CMS2_k127_5133965_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 456.0
CMS2_k127_5133965_30 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000001618 68.0
CMS2_k127_5133965_31 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily - - - 0.000000001625 70.0
CMS2_k127_5133965_32 Cellulase (glycosyl hydrolase family 5) - - - 0.0000002257 62.0
CMS2_k127_5133965_33 membrane - - - 0.000001891 55.0
CMS2_k127_5133965_35 GYD domain - - - 0.000164 49.0
CMS2_k127_5133965_4 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 454.0
CMS2_k127_5133965_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 430.0
CMS2_k127_5133965_6 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 421.0
CMS2_k127_5133965_7 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 - 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 398.0
CMS2_k127_5133965_8 PFAM Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 354.0
CMS2_k127_5133965_9 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 333.0
CMS2_k127_5137877_0 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000134 96.0
CMS2_k127_5137877_1 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000005288 69.0
CMS2_k127_5151622_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 8.262e-237 764.0
CMS2_k127_5151622_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 4.718e-215 683.0
CMS2_k127_5151622_10 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000005368 229.0
CMS2_k127_5151622_11 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000001522 216.0
CMS2_k127_5151622_12 Belongs to the UPF0282 family K07022 - - 0.000000000000000000000000000000000000000000000000000000003076 214.0
CMS2_k127_5151622_13 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000003043 189.0
CMS2_k127_5151622_14 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000006176 188.0
CMS2_k127_5151622_15 DNA polymerase beta domain protein region K09717 - - 0.000000000000000000000000000000000000000000000000001694 195.0
CMS2_k127_5151622_16 DNA RNA non-specific endonuclease K01173 - - 0.000000000000000000000000000000000000000000000000005116 190.0
CMS2_k127_5151622_17 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000008786 191.0
CMS2_k127_5151622_18 ATP dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.00000000000000000000000000000000000000000000000009231 189.0
CMS2_k127_5151622_19 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000006773 173.0
CMS2_k127_5151622_2 TIGRFAM glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 517.0
CMS2_k127_5151622_20 RNA-binding protein (contains KH domains) K06961 - - 0.00000000000000000000000000000000000000000000121 171.0
CMS2_k127_5151622_21 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.000000000000000000000000000000000000000006491 160.0
CMS2_k127_5151622_22 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000005564 148.0
CMS2_k127_5151622_23 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000001192 141.0
CMS2_k127_5151622_24 Flavodoxin domain - - - 0.000000000000000000000000000000000004651 140.0
CMS2_k127_5151622_25 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000009475 141.0
CMS2_k127_5151622_26 geranylgeranyl reductase activity K10960,K17830 - 1.3.1.101,1.3.1.111,1.3.1.83,1.3.7.11 0.0000000000000000000000000000004511 136.0
CMS2_k127_5151622_27 Transcriptional regulator K07722 - - 0.00000000000000000000000000003689 121.0
CMS2_k127_5151622_28 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000006097 118.0
CMS2_k127_5151622_29 DNA polymerase beta domain protein region K09717 - - 0.000000000000000000000006309 115.0
CMS2_k127_5151622_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 339.0
CMS2_k127_5151622_30 PFAM molybdopterin-guanine dinucleotide biosynthesis MobB region K03753 - - 0.000000000000000000001436 100.0
CMS2_k127_5151622_31 PFAM DNA polymerase, beta domain protein region K09717 - - 0.00000000000000000001446 104.0
CMS2_k127_5151622_32 Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro K07025 - - 0.000000000000000002099 94.0
CMS2_k127_5151622_33 Mechanosensitive ion channel K05802,K22051 - - 0.0000000000000001058 91.0
CMS2_k127_5151622_34 - - - - 0.0000000000000001257 88.0
CMS2_k127_5151622_35 - K00960 - 2.7.7.6 0.00000000000000792 74.0
CMS2_k127_5151622_36 - - - - 0.00000000004906 69.0
CMS2_k127_5151622_37 MFS/sugar transport protein - - - 0.000000001711 70.0
CMS2_k127_5151622_38 regulatory protein, arsR - - - 0.000000003769 61.0
CMS2_k127_5151622_39 Transcriptional regulator - - - 0.0000003603 59.0
CMS2_k127_5151622_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 305.0
CMS2_k127_5151622_40 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000001423 60.0
CMS2_k127_5151622_41 TQO small subunit DoxD K16937 - 1.8.5.2 0.000003718 57.0
CMS2_k127_5151622_42 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids K03733 GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0006003 48.0
CMS2_k127_5151622_43 COG0738 Fucose permease - - - 0.0007134 51.0
CMS2_k127_5151622_5 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002309 282.0
CMS2_k127_5151622_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005204 275.0
CMS2_k127_5151622_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003567 277.0
CMS2_k127_5151622_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000005484 249.0
CMS2_k127_5151622_9 Serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000007125 236.0
CMS2_k127_5162962_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000001406 151.0
CMS2_k127_5162962_1 Pfam:KaiC - - - 0.000004891 58.0
CMS2_k127_5162962_2 - - - - 0.000005871 52.0
CMS2_k127_5220355_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002093 280.0
CMS2_k127_5220355_1 PFAM Conserved TM helix repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000007729 236.0
CMS2_k127_5220355_2 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000007424 234.0
CMS2_k127_5220355_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000006505 149.0
CMS2_k127_5220355_4 rRNA binding - - - 0.0000000000000000005162 98.0
CMS2_k127_5237968_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 6.927e-321 1002.0
CMS2_k127_5237968_1 Cys/Met metabolism PLP-dependent enzyme K01758,K01761 - 4.4.1.1,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 583.0
CMS2_k127_5237968_10 PFAM Penicillinase repressor - - - 0.00000000000000012 85.0
CMS2_k127_5237968_11 PFAM regulatory protein AsnC Lrp family - - - 0.000000000000003412 77.0
CMS2_k127_5237968_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01697,K01738,K18926 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 441.0
CMS2_k127_5237968_3 PFAM ABC transporter K02003,K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000002724 241.0
CMS2_k127_5237968_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000001101 244.0
CMS2_k127_5237968_5 zinc finger - - - 0.000000000000000000000000000000000000000000004109 173.0
CMS2_k127_5237968_6 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001229 143.0
CMS2_k127_5237968_7 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000004352 122.0
CMS2_k127_5237968_8 Peptidase family M48 K03799 - - 0.00000000000000000001135 104.0
CMS2_k127_5237968_9 Predicted membrane protein (DUF2318) - - - 0.000000000000000003284 93.0
CMS2_k127_5259487_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 515.0
CMS2_k127_5259487_1 PFAM zinc iron permease K07238 - - 0.000000000000000000000000000000000000000000000109 177.0
CMS2_k127_5259487_2 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000003408 136.0
CMS2_k127_5259487_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000009546 136.0
CMS2_k127_5259487_4 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000002967 125.0
CMS2_k127_5259487_5 - - - - 0.0000005439 53.0
CMS2_k127_5259487_6 Sugar-specific transcriptional regulator TrmB - - - 0.0000292 51.0
CMS2_k127_5259487_7 Sugar-specific transcriptional regulator TrmB - - - 0.000503 53.0
CMS2_k127_5279117_0 NADPH quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 395.0
CMS2_k127_5279117_1 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 372.0
CMS2_k127_5279117_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000003793 190.0
CMS2_k127_5279117_3 Kelch repeat-containing protein - - - 0.00000009385 57.0
CMS2_k127_5279117_4 virion core protein (lumpy skin disease virus) - - - 0.0000008978 54.0
CMS2_k127_5279117_5 SnoaL-like polyketide cyclase - - - 0.00002439 47.0
CMS2_k127_5279117_6 amino acid activation for nonribosomal peptide biosynthetic process K05889,K12132 - 1.1.2.6,2.7.11.1 0.0002853 54.0
CMS2_k127_5280944_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K13274,K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 338.0
CMS2_k127_5280944_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001001 302.0
CMS2_k127_5280944_2 Domain of unknown function (DUF362) - - - 0.000000000000000001323 96.0
CMS2_k127_5280944_3 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000001842 79.0
CMS2_k127_5313670_0 PQQ enzyme repeat - - - 0.00000000000000000000000000000000000000000000000000003341 209.0
CMS2_k127_5313670_1 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000001748 177.0
CMS2_k127_5313670_2 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0006373 44.0
CMS2_k127_5416677_0 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 290.0
CMS2_k127_5416677_1 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000004822 255.0
CMS2_k127_5416677_10 Cytochrome b5-like Heme/Steroid binding domain - - - 0.0000000000000000000000000000000000002383 150.0
CMS2_k127_5416677_11 Peptidase A4 family - - - 0.0000000000000000000000000000000000004175 152.0
CMS2_k127_5416677_12 KaiC - - - 0.000000000000000000000000000000000001776 147.0
CMS2_k127_5416677_13 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000004595 139.0
CMS2_k127_5416677_14 DGC domain - - - 0.00000000000000000000000000000000032 135.0
CMS2_k127_5416677_15 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000006419 147.0
CMS2_k127_5416677_16 Protein of unknown function DUF72 - - - 0.000000000000000000000000000165 117.0
CMS2_k127_5416677_17 DGC domain - - - 0.0000000000000000000000008372 108.0
CMS2_k127_5416677_18 Major Facilitator Superfamily - - - 0.000000000000000000001623 108.0
CMS2_k127_5416677_19 Universal stress protein family - - - 0.00000000000000000154 91.0
CMS2_k127_5416677_2 binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000005099 239.0
CMS2_k127_5416677_20 regulatory protein, arsR K03892 - - 0.000000000000000001849 90.0
CMS2_k127_5416677_21 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000008798 87.0
CMS2_k127_5416677_22 - - - - 0.0000000000000006278 87.0
CMS2_k127_5416677_23 - - - - 0.0000000000009076 70.0
CMS2_k127_5416677_24 - - - - 0.0000005434 60.0
CMS2_k127_5416677_25 helix_turn_helix, Arsenical Resistance Operon Repressor K22043 - - 0.00000343 53.0
CMS2_k127_5416677_26 metallopeptidase activity K01218,K13276 - 3.2.1.78 0.00001298 58.0
CMS2_k127_5416677_27 PQQ-like domain K17760 - 1.1.9.1 0.00009646 56.0
CMS2_k127_5416677_3 DNA polymerase LigD, polymerase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001027 240.0
CMS2_k127_5416677_4 Major facilitator Superfamily K08153 - - 0.0000000000000000000000000000000000000000000000000000000000000000004317 245.0
CMS2_k127_5416677_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000008015 188.0
CMS2_k127_5416677_6 DNA helicase - - - 0.00000000000000000000000000000000000000000000000009009 201.0
CMS2_k127_5416677_7 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000117 171.0
CMS2_k127_5416677_8 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000001309 177.0
CMS2_k127_5416677_9 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000001756 160.0
CMS2_k127_5470157_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1313.0
CMS2_k127_5470157_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 2.063e-315 1007.0
CMS2_k127_5470157_2 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 417.0
CMS2_k127_5470157_3 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000000000006733 167.0
CMS2_k127_5470157_4 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.0000000000000000000000344 102.0
CMS2_k127_5470157_5 Belongs to the 'phage' integrase family - - - 0.0001378 53.0
CMS2_k127_551232_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 306.0
CMS2_k127_551232_1 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000218 190.0
CMS2_k127_551232_10 rRNA binding K02944 - - 0.000000000000006144 76.0
CMS2_k127_551232_11 NUDIX domain K03574 - 3.6.1.55 0.00000000002218 69.0
CMS2_k127_551232_12 RNA-binding protein K07574 - - 0.00000001294 62.0
CMS2_k127_551232_13 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000001457 59.0
CMS2_k127_551232_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000017 172.0
CMS2_k127_551232_3 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000001994 174.0
CMS2_k127_551232_4 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000004874 162.0
CMS2_k127_551232_5 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000001185 126.0
CMS2_k127_551232_6 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000001754 101.0
CMS2_k127_551232_7 Belongs to the PDCD5 family K06875 - - 0.0000000000000000001822 91.0
CMS2_k127_551232_8 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.000000000000001565 82.0
CMS2_k127_551232_9 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.000000000000002267 82.0
CMS2_k127_5614974_0 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 435.0
CMS2_k127_5614974_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 343.0
CMS2_k127_5614974_2 PFAM ATP-grasp domain K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000356 247.0
CMS2_k127_5614974_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000005605 211.0
CMS2_k127_5614974_4 UPF0056 membrane protein K05595 - - 0.0000000000000000000000000000000000000004123 156.0
CMS2_k127_6115122_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1169.0
CMS2_k127_6115122_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.417e-251 789.0
CMS2_k127_6115122_10 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001609 263.0
CMS2_k127_6115122_11 Restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000002585 230.0
CMS2_k127_6115122_12 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000002801 229.0
CMS2_k127_6115122_13 peptidase - - - 0.000000000000000000000000000000000000006429 152.0
CMS2_k127_6115122_14 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000005843 148.0
CMS2_k127_6115122_15 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000004056 131.0
CMS2_k127_6115122_16 Belongs to the SUI1 family K03113 - - 0.00000000000000000000000000000005526 127.0
CMS2_k127_6115122_17 Methyltransferase domain - - - 0.00000000000000000000000001494 117.0
CMS2_k127_6115122_18 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000003195 120.0
CMS2_k127_6115122_2 metallochaperone-like domain - - - 4.294e-227 722.0
CMS2_k127_6115122_20 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000466 105.0
CMS2_k127_6115122_21 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000002479 108.0
CMS2_k127_6115122_22 signal transduction protein with CBS domains - - - 0.0000000000000000000004575 107.0
CMS2_k127_6115122_23 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000001362 88.0
CMS2_k127_6115122_24 PFAM PEGA domain - - - 0.0000000000000001052 94.0
CMS2_k127_6115122_25 YHS domain - - - 0.0000000000000007307 77.0
CMS2_k127_6115122_26 CBS domain - - - 0.0000000000002219 81.0
CMS2_k127_6115122_27 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000009393 81.0
CMS2_k127_6115122_28 Redoxin K03564 - 1.11.1.15 0.0000000001058 63.0
CMS2_k127_6115122_29 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000005512 65.0
CMS2_k127_6115122_3 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 576.0
CMS2_k127_6115122_30 Tfp pilus assembly protein FimV - - - 0.0000007653 56.0
CMS2_k127_6115122_31 - - - - 0.000007611 51.0
CMS2_k127_6115122_32 membrane-associated protein domain - - - 0.00001102 51.0
CMS2_k127_6115122_33 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000562 55.0
CMS2_k127_6115122_34 COG1522 Transcriptional regulators - - - 0.00005963 48.0
CMS2_k127_6115122_35 Lrp/AsnC ligand binding domain - - - 0.00006391 50.0
CMS2_k127_6115122_36 Transcriptional regulator PadR-like family - - - 0.0001275 51.0
CMS2_k127_6115122_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 432.0
CMS2_k127_6115122_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 426.0
CMS2_k127_6115122_6 PFAM elongation factor Tu domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 379.0
CMS2_k127_6115122_7 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 355.0
CMS2_k127_6115122_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 365.0
CMS2_k127_6115122_9 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 296.0
CMS2_k127_6131354_0 - - - - 0.00000000000000002492 87.0
CMS2_k127_6131354_1 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.00000004758 60.0
CMS2_k127_6192358_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 602.0
CMS2_k127_6192358_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 584.0
CMS2_k127_6192358_10 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000008172 109.0
CMS2_k127_6192358_11 GH3 auxin-responsive promoter - - - 0.0000000000000000000008543 108.0
CMS2_k127_6192358_12 - - - - 0.000000000000000000001995 94.0
CMS2_k127_6192358_13 GIY-YIG catalytic domain K07461 - - 0.0000000000000003735 81.0
CMS2_k127_6192358_16 Phytol kinase K15892,K18678 - 2.7.1.182,2.7.1.216 0.0000001632 63.0
CMS2_k127_6192358_2 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 397.0
CMS2_k127_6192358_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 379.0
CMS2_k127_6192358_4 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000004 243.0
CMS2_k127_6192358_5 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000001091 233.0
CMS2_k127_6192358_6 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000001724 224.0
CMS2_k127_6192358_7 - - - - 0.000000000000000000000000000000000000000000000000000000000006315 228.0
CMS2_k127_6192358_8 - - - - 0.0000000000000000000000000000000000000000000000000000000003227 211.0
CMS2_k127_6192358_9 DEAD DEAH box helicase domain protein K10896 - - 0.000000000000000000000000000001038 130.0
CMS2_k127_6316492_0 - - - - 0.0000000000002262 76.0
CMS2_k127_6316492_1 - - - - 0.00001992 49.0
CMS2_k127_6374259_1 thiolester hydrolase activity - - - 0.0000000000000007798 89.0
CMS2_k127_6374259_2 PFAM Collagen triple helix - - - 0.000000000003094 75.0
CMS2_k127_6492489_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 8.896e-198 634.0
CMS2_k127_6492489_1 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 557.0
CMS2_k127_6492489_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000002358 145.0
CMS2_k127_6492489_11 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000002666 136.0
CMS2_k127_6492489_12 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000783 93.0
CMS2_k127_6492489_13 4 iron, 4 sulfur cluster binding K00205,K02573 - - 0.0000000000000000003058 90.0
CMS2_k127_6492489_14 4 iron, 4 sulfur cluster binding K00226,K02574 - 1.3.98.1 0.00000000001555 66.0
CMS2_k127_6492489_15 Ribosomal protein S30 K02983 - - 0.00000000007109 64.0
CMS2_k127_6492489_16 Thioredoxin - - - 0.00000003243 59.0
CMS2_k127_6492489_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 416.0
CMS2_k127_6492489_3 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 383.0
CMS2_k127_6492489_4 PFAM ABC transporter related K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 314.0
CMS2_k127_6492489_5 SMART zinc finger, CDGSH-type domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 300.0
CMS2_k127_6492489_6 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004041 290.0
CMS2_k127_6492489_7 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003108 278.0
CMS2_k127_6492489_8 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000001577 241.0
CMS2_k127_6492489_9 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000003327 180.0
CMS2_k127_6539943_0 Protein of unknown function (DUF996) - - - 0.0000000000000000000000000000001319 131.0
CMS2_k127_6603189_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 577.0
CMS2_k127_6603189_1 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 433.0
CMS2_k127_6603189_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.00000000000000000000000009389 110.0
CMS2_k127_6603189_11 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000001465 109.0
CMS2_k127_6603189_12 Putative RNA methyltransferase K09142 - - 0.0000000000000007035 78.0
CMS2_k127_6603189_13 - - - - 0.000000003668 62.0
CMS2_k127_6603189_14 belongs to the iron- containing alcohol dehydrogenase family K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0003215 45.0
CMS2_k127_6603189_2 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 300.0
CMS2_k127_6603189_3 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001608 273.0
CMS2_k127_6603189_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000003955 208.0
CMS2_k127_6603189_5 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.000000000000000000000000000000000000000000000000000002289 196.0
CMS2_k127_6603189_6 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000004547 197.0
CMS2_k127_6603189_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000002855 198.0
CMS2_k127_6603189_8 Putative RNA methyltransferase K09142 - - 0.0000000000000000000000000000000000000000001431 166.0
CMS2_k127_6603189_9 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000000006129 148.0
CMS2_k127_6613720_0 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 340.0
CMS2_k127_6613720_1 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000009984 123.0
CMS2_k127_6613720_2 integrase family K04763 - - 0.00000000000000000009007 102.0
CMS2_k127_6613720_3 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06131 - - 0.000000000002235 74.0
CMS2_k127_6613720_4 Bacterial PH domain - - - 0.0000001102 58.0
CMS2_k127_6719207_0 TIGRFAM lysine 2,3-aminomutase YodO family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 465.0
CMS2_k127_6719207_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 297.0
CMS2_k127_6719207_2 by modhmm K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000008337 211.0
CMS2_k127_6719207_3 - - - - 0.000000000000000000000002946 106.0
CMS2_k127_6720740_0 response to heat K03696 - - 2.058e-300 936.0
CMS2_k127_6720740_1 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 397.0
CMS2_k127_6720740_2 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000001691 204.0
CMS2_k127_6720740_3 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000001622 142.0
CMS2_k127_6808801_0 DEAD DEAH box helicase domain protein K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 542.0
CMS2_k127_6808801_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 513.0
CMS2_k127_6808801_10 Protein of unknown function (DUF3243) - - - 0.00000000000000000000003137 101.0
CMS2_k127_6808801_11 - K00960 - 2.7.7.6 0.00000000000001033 74.0
CMS2_k127_6808801_12 Belongs to the universal stress protein A family - - - 0.00000000000008009 76.0
CMS2_k127_6808801_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000815 79.0
CMS2_k127_6808801_14 Belongs to the eukaryotic ribosomal protein eL33 family K02917 - - 0.000000000000742 72.0
CMS2_k127_6808801_15 RNA-binding protein contains TRAM domain - - - 0.00000000004691 66.0
CMS2_k127_6808801_16 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000001186 68.0
CMS2_k127_6808801_17 - K00960 - 2.7.7.6 0.00000001412 60.0
CMS2_k127_6808801_18 reductase - - - 0.0000001669 55.0
CMS2_k127_6808801_2 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 361.0
CMS2_k127_6808801_3 epimerase dehydratase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 328.0
CMS2_k127_6808801_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004186 254.0
CMS2_k127_6808801_5 Related to alanyl-tRNA synthetase HxxxH domain K01872,K07050 GO:0002161,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000002589 237.0
CMS2_k127_6808801_6 COGs COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.00000000000000000000000000000000000000000000000000000001091 200.0
CMS2_k127_6808801_7 - - - - 0.000000000000000000000000000000000000008204 154.0
CMS2_k127_6808801_8 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000002447 136.0
CMS2_k127_6808801_9 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000003517 121.0
CMS2_k127_7012805_0 Pfam:DUF650 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 456.0
CMS2_k127_7012805_1 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000001572 118.0
CMS2_k127_7034730_0 Thiamine pyrophosphate enzyme, central domain K04103 - 4.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006579 424.0
CMS2_k127_7034730_1 Biogenesis protein - - - 0.0000000000000000000000001622 113.0
CMS2_k127_73950_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 555.0
CMS2_k127_73950_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 464.0
CMS2_k127_73950_10 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000007491 253.0
CMS2_k127_73950_11 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002515 264.0
CMS2_k127_73950_12 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000001989 242.0
CMS2_k127_73950_13 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000001584 209.0
CMS2_k127_73950_14 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000003594 209.0
CMS2_k127_73950_15 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000001344 181.0
CMS2_k127_73950_16 LemA family K03744 - - 0.00000000000000000000000000000000000000548 152.0
CMS2_k127_73950_18 PFAM Glycosyl transferase, group 1 K16150 - 2.4.1.11 0.000000000000000000000000000000000000305 155.0
CMS2_k127_73950_19 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000006344 109.0
CMS2_k127_73950_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 466.0
CMS2_k127_73950_20 Methanol dehydrogenase K06872 - - 0.0000000000000000000001156 106.0
CMS2_k127_73950_21 Protein of unknown function (DUF861) K06995 - - 0.000000000000000000002303 96.0
CMS2_k127_73950_22 mechanosensitive ion channel K03442 - - 0.0000000000000000000229 103.0
CMS2_k127_73950_23 response regulator, receiver K07669 - - 0.000000000000000001402 89.0
CMS2_k127_73950_24 membrane - - - 0.000000000000000006448 89.0
CMS2_k127_73950_25 acetyltransferase - - - 0.000000000000003588 85.0
CMS2_k127_73950_26 TIGRFAM desulfoferrodoxin FeS4 iron-binding domain K05919 - 1.15.1.2 0.000000002122 60.0
CMS2_k127_73950_28 Transcriptional regulator K03718 - - 0.0000139 52.0
CMS2_k127_73950_29 metalloendopeptidase activity - - - 0.0005553 49.0
CMS2_k127_73950_3 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 443.0
CMS2_k127_73950_30 AP endonuclease family 2 - - - 0.0008115 50.0
CMS2_k127_73950_4 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 434.0
CMS2_k127_73950_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 436.0
CMS2_k127_73950_6 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 381.0
CMS2_k127_73950_7 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 360.0
CMS2_k127_73950_8 Protein of unknown function (DUF1512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 324.0
CMS2_k127_73950_9 Iron permease FTR1 family K07243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002457 282.0
CMS2_k127_788388_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 4.137e-234 753.0
CMS2_k127_788388_1 RNase L inhibitor K06174 - - 6.812e-210 668.0
CMS2_k127_788388_10 HELICc2 K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 446.0
CMS2_k127_788388_11 SMC proteins Flexible Hinge Domain K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 459.0
CMS2_k127_788388_12 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 417.0
CMS2_k127_788388_13 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 391.0
CMS2_k127_788388_14 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 390.0
CMS2_k127_788388_15 4Fe-4S single cluster domain K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 364.0
CMS2_k127_788388_16 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 351.0
CMS2_k127_788388_17 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 347.0
CMS2_k127_788388_18 Molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 327.0
CMS2_k127_788388_19 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 318.0
CMS2_k127_788388_2 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 5.396e-209 662.0
CMS2_k127_788388_20 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 312.0
CMS2_k127_788388_21 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 316.0
CMS2_k127_788388_22 Belongs to the UPF0284 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 312.0
CMS2_k127_788388_23 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 311.0
CMS2_k127_788388_24 ABC-type cobalt transport system ATPase component K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 298.0
CMS2_k127_788388_25 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 292.0
CMS2_k127_788388_26 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002082 282.0
CMS2_k127_788388_27 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000671 271.0
CMS2_k127_788388_28 ATPases associated with a variety of cellular activities K16786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000461 255.0
CMS2_k127_788388_29 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000005305 247.0
CMS2_k127_788388_3 PFAM Chaperonin Cpn60 TCP-1 K22447 - - 1.103e-195 625.0
CMS2_k127_788388_30 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000002333 233.0
CMS2_k127_788388_31 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000008287 232.0
CMS2_k127_788388_32 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000001246 229.0
CMS2_k127_788388_33 PFAM Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000004853 227.0
CMS2_k127_788388_34 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000003104 216.0
CMS2_k127_788388_35 hmm pf01073 K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000005558 219.0
CMS2_k127_788388_36 mevalonate kinase activity K00869,K15633 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006066,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006694,GO:0006695,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016126,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653 2.7.1.36,5.4.2.12 0.000000000000000000000000000000000000000000000000000000000161 215.0
CMS2_k127_788388_37 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000168 229.0
CMS2_k127_788388_38 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000001935 202.0
CMS2_k127_788388_39 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000003204 187.0
CMS2_k127_788388_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 5.973e-195 625.0
CMS2_k127_788388_40 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000002919 185.0
CMS2_k127_788388_41 diphthine-ammonia ligase activity K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000002281 174.0
CMS2_k127_788388_42 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000006442 177.0
CMS2_k127_788388_43 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000358 171.0
CMS2_k127_788388_44 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000001336 158.0
CMS2_k127_788388_45 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000009014 157.0
CMS2_k127_788388_46 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000002137 152.0
CMS2_k127_788388_47 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000006684 145.0
CMS2_k127_788388_48 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000001085 150.0
CMS2_k127_788388_49 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000008739 153.0
CMS2_k127_788388_5 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 606.0
CMS2_k127_788388_50 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000001215 153.0
CMS2_k127_788388_51 Cytidylyltransferase K19712 - 2.7.7.62 0.00000000000000000000000000000000000214 145.0
CMS2_k127_788388_52 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000003752 143.0
CMS2_k127_788388_53 Segregation and condensation complex subunit ScpB K06024 - - 0.0000000000000000000000000000000001796 139.0
CMS2_k127_788388_54 THUMP domain K06963 - - 0.000000000000000000000000000000000219 138.0
CMS2_k127_788388_55 PFAM Phosphatidylglycerophosphatase A - - - 0.0000000000000000000000000000000002799 136.0
CMS2_k127_788388_56 PFAM Cobalt transport protein K16785 - - 0.0000000000000000000000000000000005291 141.0
CMS2_k127_788388_57 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.000000000000000000000000000000001052 137.0
CMS2_k127_788388_58 PFAM ribosomal protein S8E K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000002447 126.0
CMS2_k127_788388_59 PFAM HhH-GPD family protein K10773 - 4.2.99.18 0.0000000000000000000000000002739 122.0
CMS2_k127_788388_6 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 537.0
CMS2_k127_788388_60 Cytidylyltransferase K19712 - 2.7.7.62 0.0000000000000000000000000006976 121.0
CMS2_k127_788388_61 Thymidylate synthase K00560 - 2.1.1.45 0.00000000000000000000000007451 119.0
CMS2_k127_788388_62 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000001402 117.0
CMS2_k127_788388_63 - - - - 0.00000000000000000000003382 107.0
CMS2_k127_788388_64 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000001794 109.0
CMS2_k127_788388_65 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000732 101.0
CMS2_k127_788388_66 GyrI-like small molecule binding domain - - - 0.0000000000000000001984 91.0
CMS2_k127_788388_67 Domain of unknown function (DUF4342) - - - 0.0000000000000000007023 90.0
CMS2_k127_788388_68 binds to the 23S rRNA K02921 - - 0.000000000000000001844 88.0
CMS2_k127_788388_69 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000004615 94.0
CMS2_k127_788388_7 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 484.0
CMS2_k127_788388_70 PFAM Glycosyl transferase family 4 K01001 - 2.7.8.15 0.0000000000000001243 91.0
CMS2_k127_788388_71 Transcriptional regulator K07108,K22206 - - 0.0000000000000002993 83.0
CMS2_k127_788388_72 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016043,GO:0044424,GO:0044464,GO:0071840 - 0.0000000000000003944 83.0
CMS2_k127_788388_73 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.0000000000000008517 81.0
CMS2_k127_788388_74 - - - - 0.0000000000000008629 85.0
CMS2_k127_788388_75 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000004052 74.0
CMS2_k127_788388_76 Fibronectin type III domain K03933 - - 0.000000000004623 77.0
CMS2_k127_788388_77 Kinase binding protein CGI-121 K09119 - - 0.0000000005357 67.0
CMS2_k127_788388_78 TIGRFAM MoaD family protein K03636 - - 0.000000002209 62.0
CMS2_k127_788388_8 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 442.0
CMS2_k127_788388_80 DREV methyltransferase - - - 0.000000561 59.0
CMS2_k127_788388_81 DNA topoisomerase, type IA, central domain protein K03168,K03169 - 5.99.1.2 0.0000007305 54.0
CMS2_k127_788388_82 Transcription factor Pcc1 K09741 - - 0.000004554 52.0
CMS2_k127_788388_83 chromosome segregation and condensation protein ScpA K05896 - - 0.00001451 55.0
CMS2_k127_788388_84 Protein of unknown function (DUF1616) - - - 0.0001648 50.0
CMS2_k127_788388_85 Major Facilitator Superfamily - - - 0.0002839 53.0
CMS2_k127_788388_86 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0002934 48.0
CMS2_k127_788388_9 Rhodanese-like domain K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 440.0
CMS2_k127_833961_0 Superfamily I DNA and RNA - - - 5.135e-280 929.0
CMS2_k127_833961_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 370.0
CMS2_k127_833961_10 Acyltransferase - - - 0.000301 53.0
CMS2_k127_833961_2 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000002899 196.0
CMS2_k127_833961_3 Glycosyl transferase family group 2 K19003 - 2.4.1.336 0.000000000000000000000000000000000000003418 163.0
CMS2_k127_833961_4 Tubulin like - - - 0.0000000000000000000000000002849 133.0
CMS2_k127_833961_5 snRNP Sm proteins K04796 - - 0.000000000000000000003089 94.0
CMS2_k127_833961_6 binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000007832 84.0
CMS2_k127_833961_7 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.00000000000000005882 89.0
CMS2_k127_833961_8 - - - - 0.000001136 61.0
CMS2_k127_833961_9 - - - - 0.000002284 57.0
CMS2_k127_958415_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 538.0
CMS2_k127_958415_1 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000001715 176.0
CMS2_k127_958415_2 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.000000000000000000000000000000000000005248 153.0
CMS2_k127_958415_3 GYD domain - - - 0.0000000000000000000000000000009437 125.0
CMS2_k127_958415_4 Protein of unknown function DUF72 - - - 0.0000000000000009872 80.0
CMS2_k127_958415_5 Protein of unknown function DUF72 - - - 0.0000000000003364 80.0