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Overview

ID MAG00462
Name CMS2_bin.78
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Campylobacterota
Class Campylobacteria
Order Campylobacterales
Family Sulfurimonadaceae
Genus S145-25
Species
Assembly information
Completeness (%) 91.73
Contamination (%) 0.53
GC content (%) 53.0
N50 (bp) 26,957
Genome size (bp) 2,154,991

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2060

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1027090_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1422.0
CMS2_k127_1027090_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1301.0
CMS2_k127_1027090_10 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 604.0
CMS2_k127_1027090_11 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 578.0
CMS2_k127_1027090_12 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 558.0
CMS2_k127_1027090_13 Peptidase, M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 504.0
CMS2_k127_1027090_14 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 482.0
CMS2_k127_1027090_15 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 480.0
CMS2_k127_1027090_16 Belongs to the agmatine deiminase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 473.0
CMS2_k127_1027090_17 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 466.0
CMS2_k127_1027090_18 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 462.0
CMS2_k127_1027090_19 membrane K15270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 444.0
CMS2_k127_1027090_2 cytochrome c - - - 0.0 1248.0
CMS2_k127_1027090_20 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 441.0
CMS2_k127_1027090_21 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 433.0
CMS2_k127_1027090_22 apolipoprotein N-acyltransferase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 441.0
CMS2_k127_1027090_23 peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 424.0
CMS2_k127_1027090_24 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 411.0
CMS2_k127_1027090_25 metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 400.0
CMS2_k127_1027090_26 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 389.0
CMS2_k127_1027090_27 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 370.0
CMS2_k127_1027090_28 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 372.0
CMS2_k127_1027090_29 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 346.0
CMS2_k127_1027090_3 Glycolate oxidase subunit K00104 - 1.1.3.15 3.556e-259 803.0
CMS2_k127_1027090_30 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 339.0
CMS2_k127_1027090_31 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 325.0
CMS2_k127_1027090_32 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 328.0
CMS2_k127_1027090_33 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000248 277.0
CMS2_k127_1027090_34 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009957 278.0
CMS2_k127_1027090_35 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000001404 250.0
CMS2_k127_1027090_36 Plasminogen-binding protein pgbA N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000001389 242.0
CMS2_k127_1027090_37 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000006399 232.0
CMS2_k127_1027090_38 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000008122 236.0
CMS2_k127_1027090_39 DnaJ domain protein K05801 - - 0.000000000000000000000000000000000000000000000000000000000000000003356 235.0
CMS2_k127_1027090_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 5.989e-242 755.0
CMS2_k127_1027090_40 Nudix domain K08077 - 3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000001307 229.0
CMS2_k127_1027090_41 membrane K08973 - - 0.00000000000000000000000000000000000000000000000000000000000000002066 228.0
CMS2_k127_1027090_42 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000003489 223.0
CMS2_k127_1027090_43 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000001795 217.0
CMS2_k127_1027090_44 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000003857 235.0
CMS2_k127_1027090_45 - - - - 0.00000000000000000000000000000000000000000000000000000000007413 207.0
CMS2_k127_1027090_46 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000009244 208.0
CMS2_k127_1027090_47 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000002027 205.0
CMS2_k127_1027090_48 MltA-interacting MipA family protein K07274 - - 0.00000000000000000000000000000000000000000000000000002729 194.0
CMS2_k127_1027090_49 - - - - 0.000000000000000000000000000000000000000000000000001948 183.0
CMS2_k127_1027090_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 8.269e-241 754.0
CMS2_k127_1027090_50 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000000000000000004964 177.0
CMS2_k127_1027090_51 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.000000000000000000000000000000000000000916 150.0
CMS2_k127_1027090_52 NlpC/P60 family K13695 - - 0.00000000000000000000000000000000000003004 148.0
CMS2_k127_1027090_53 - - - - 0.0000000000000000000000000000000000003242 143.0
CMS2_k127_1027090_54 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000008164 133.0
CMS2_k127_1027090_55 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000478 112.0
CMS2_k127_1027090_56 Preprotein translocase, YajC subunit K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000005558 106.0
CMS2_k127_1027090_57 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000003311 102.0
CMS2_k127_1027090_58 - - - - 0.0000000000002371 71.0
CMS2_k127_1027090_59 Prokaryotic metallothionein K06950 - - 0.000000000002569 69.0
CMS2_k127_1027090_6 TonB-dependent copper receptor K02014 - - 3.043e-230 732.0
CMS2_k127_1027090_60 Cache domain - - - 0.0003197 48.0
CMS2_k127_1027090_7 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 3.496e-213 676.0
CMS2_k127_1027090_8 Belongs to the DEAD box helicase family - - - 1.07e-200 634.0
CMS2_k127_1027090_9 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.797e-196 616.0
CMS2_k127_1029379_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 5.206e-317 993.0
CMS2_k127_1029379_1 COGs COG1252 NADH dehydrogenase FAD-containing subunit K17218 - 1.8.5.4 9.538e-293 901.0
CMS2_k127_1029379_10 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000003407 178.0
CMS2_k127_1029379_11 - - - - 0.00000000000000000000000000000000001633 153.0
CMS2_k127_1029379_12 - - - - 0.0000000000000000001872 88.0
CMS2_k127_1029379_2 Hpt sensor hybrid histidine kinase - - - 7.081e-247 793.0
CMS2_k127_1029379_3 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 509.0
CMS2_k127_1029379_4 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 350.0
CMS2_k127_1029379_5 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 317.0
CMS2_k127_1029379_6 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001424 278.0
CMS2_k127_1029379_7 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000001211 231.0
CMS2_k127_1029379_8 COG0242 N-formylmethionyl-tRNA deformylase - - - 0.00000000000000000000000000000000000000000000000000000000001108 216.0
CMS2_k127_1029379_9 - - - - 0.000000000000000000000000000000000000000000000000001707 188.0
CMS2_k127_1030414_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1545.0
CMS2_k127_1030414_1 COGs COG3864 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 544.0
CMS2_k127_1030414_10 YHS domain K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 353.0
CMS2_k127_1030414_11 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 359.0
CMS2_k127_1030414_12 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 346.0
CMS2_k127_1030414_13 cation efflux system protein K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 349.0
CMS2_k127_1030414_14 Protein of unknown function (DUF819) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 324.0
CMS2_k127_1030414_15 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 300.0
CMS2_k127_1030414_16 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 299.0
CMS2_k127_1030414_17 COG2346 Truncated hemoglobins K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004068 245.0
CMS2_k127_1030414_18 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000000000000000000000000000000000539 216.0
CMS2_k127_1030414_19 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000000000000000000005649 165.0
CMS2_k127_1030414_2 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 542.0
CMS2_k127_1030414_20 response regulator - - - 0.000000000000000000000000000000000000000831 155.0
CMS2_k127_1030414_21 YtkA-like - - - 0.00000000000000000000000000000006337 128.0
CMS2_k127_1030414_22 beta-lactamase activity K07126,K15474 - - 0.000000000000000000001319 98.0
CMS2_k127_1030414_23 endonuclease containing a URI domain K07461 - - 0.000000000000000004433 98.0
CMS2_k127_1030414_24 Cytochrome c - - - 0.00000000000000003882 83.0
CMS2_k127_1030414_25 Belongs to the UPF0312 family - - - 0.0000000000000008895 83.0
CMS2_k127_1030414_3 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 525.0
CMS2_k127_1030414_4 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 509.0
CMS2_k127_1030414_5 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 484.0
CMS2_k127_1030414_6 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 424.0
CMS2_k127_1030414_7 COG1538 Outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 391.0
CMS2_k127_1030414_8 COGs COG3864 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 373.0
CMS2_k127_1030414_9 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 355.0
CMS2_k127_1035118_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 6.14e-252 787.0
CMS2_k127_1035118_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 1.58e-224 706.0
CMS2_k127_1035118_10 Pseudouridine synthase K06177,K06179,K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 312.0
CMS2_k127_1035118_11 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 311.0
CMS2_k127_1035118_13 SpoIIAA-like - - - 0.000000000000000000000000000000000000001653 150.0
CMS2_k127_1035118_14 Histidine kinase - - - 0.000000000000000000000000000000000000004667 152.0
CMS2_k127_1035118_15 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.000000000000000000000000000000000000131 146.0
CMS2_k127_1035118_16 COG1309 Transcriptional regulator - - - 0.00000000000000000000000000001916 122.0
CMS2_k127_1035118_17 - - - - 0.0000000000000000000000000002355 117.0
CMS2_k127_1035118_18 DNA-binding protein VF530 - - - 0.000000000000000000000000005531 112.0
CMS2_k127_1035118_19 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000004102 106.0
CMS2_k127_1035118_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 586.0
CMS2_k127_1035118_20 - - - - 0.0000000000007562 72.0
CMS2_k127_1035118_3 conserved protein UCP016719 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 496.0
CMS2_k127_1035118_4 Ecdysteroid kinase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 439.0
CMS2_k127_1035118_5 Membrane protease subunits - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 400.0
CMS2_k127_1035118_6 diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 353.0
CMS2_k127_1035118_7 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 350.0
CMS2_k127_1035118_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 334.0
CMS2_k127_1035118_9 Anhydro-N-acetylmuramic acid kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 333.0
CMS2_k127_1064329_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 4056.0
CMS2_k127_1064329_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.0 1044.0
CMS2_k127_1064329_10 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 385.0
CMS2_k127_1064329_11 Amino Acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 365.0
CMS2_k127_1064329_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 292.0
CMS2_k127_1064329_13 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000225 263.0
CMS2_k127_1064329_14 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006687 258.0
CMS2_k127_1064329_15 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000000000000000000001075 213.0
CMS2_k127_1064329_16 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000000000000000000007236 200.0
CMS2_k127_1064329_17 - K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000001821 196.0
CMS2_k127_1064329_19 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000003935 167.0
CMS2_k127_1064329_2 AAA domain - - - 8.047e-240 766.0
CMS2_k127_1064329_20 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000000000000000001033 168.0
CMS2_k127_1064329_21 Universal stress protein family - - - 0.000000000000000000000000000000000000000006883 165.0
CMS2_k127_1064329_22 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000003486 157.0
CMS2_k127_1064329_23 RND family efflux transporter, MFP subunit - - - 0.0000000000000000000000002268 119.0
CMS2_k127_1064329_24 DNA polymerase K02347 - - 0.000000000000000000005639 94.0
CMS2_k127_1064329_27 efflux transmembrane transporter activity - - - 0.0002902 53.0
CMS2_k127_1064329_3 Spermine/spermidine synthase domain K00797 - 2.5.1.16 3.646e-239 766.0
CMS2_k127_1064329_4 Belongs to the RtcB family K14415 - 6.5.1.3 1.371e-217 689.0
CMS2_k127_1064329_5 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007203 572.0
CMS2_k127_1064329_6 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 506.0
CMS2_k127_1064329_7 Membrane protease subunits - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 425.0
CMS2_k127_1064329_8 PFAM Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 399.0
CMS2_k127_1064329_9 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 402.0
CMS2_k127_1082804_0 Histidine kinase - - - 0.0 1171.0
CMS2_k127_1082804_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1039.0
CMS2_k127_1082804_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 9.263e-254 795.0
CMS2_k127_1082804_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.28e-213 671.0
CMS2_k127_1082804_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 288.0
CMS2_k127_1082804_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002932 289.0
CMS2_k127_1082804_6 COG1055 Na H antiporter NhaD and related arsenite - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003966 245.0
CMS2_k127_1082804_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000006165 221.0
CMS2_k127_1082804_8 Response regulator receiver K07814 - - 0.0000000000000000000000000000000000000000000000000002497 186.0
CMS2_k127_1082804_9 - - - - 0.000000000000000000000000000000007901 132.0
CMS2_k127_1131113_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2410.0
CMS2_k127_1131113_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1578.0
CMS2_k127_1131113_10 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 457.0
CMS2_k127_1131113_11 Permease, YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 411.0
CMS2_k127_1131113_12 permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 409.0
CMS2_k127_1131113_13 Co Zn Cd efflux system component K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 359.0
CMS2_k127_1131113_14 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 347.0
CMS2_k127_1131113_15 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 342.0
CMS2_k127_1131113_16 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 323.0
CMS2_k127_1131113_17 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 317.0
CMS2_k127_1131113_18 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 310.0
CMS2_k127_1131113_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 315.0
CMS2_k127_1131113_2 Molecular chaperone. Has ATPase activity K04079 - - 1.322e-315 977.0
CMS2_k127_1131113_20 RecO N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 301.0
CMS2_k127_1131113_21 PFAM Glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 297.0
CMS2_k127_1131113_22 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 286.0
CMS2_k127_1131113_23 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002248 284.0
CMS2_k127_1131113_24 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003054 278.0
CMS2_k127_1131113_25 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002286 262.0
CMS2_k127_1131113_26 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000107 240.0
CMS2_k127_1131113_27 Peptidase A24 K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000005819 246.0
CMS2_k127_1131113_28 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000002558 228.0
CMS2_k127_1131113_29 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000000000000000000000000000000002052 225.0
CMS2_k127_1131113_3 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 3.114e-254 788.0
CMS2_k127_1131113_30 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000001594 220.0
CMS2_k127_1131113_31 MCRA family - - - 0.000000000000000000000000000000000000000000000000000000000001386 211.0
CMS2_k127_1131113_32 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000001199 215.0
CMS2_k127_1131113_33 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000003413 199.0
CMS2_k127_1131113_34 DNA RNA helicase - - - 0.000000000000000000000000000000000000000000000000009057 201.0
CMS2_k127_1131113_35 MCRA family - - - 0.000000000000000000000000000000000000000000004704 164.0
CMS2_k127_1131113_36 - - - - 0.00000000000000000000000000000000000000000002443 167.0
CMS2_k127_1131113_37 Nucleoside 2-deoxyribosyltransferase K08728 - 2.4.2.6 0.00000000000000000000000000000000000000001341 159.0
CMS2_k127_1131113_38 DnaK suppressor protein K06204 - - 0.00000000000000000000000000000000000000007246 153.0
CMS2_k127_1131113_39 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000000000001333 135.0
CMS2_k127_1131113_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 9.157e-197 621.0
CMS2_k127_1131113_40 Myosin-crossreactive antigen K10254 - 4.2.1.53 0.0000000000000000000000000000000157 129.0
CMS2_k127_1131113_41 - - - - 0.0000000000000000000000000003885 129.0
CMS2_k127_1131113_42 Redox-active disulfide protein - - - 0.000000000000000000000000002165 121.0
CMS2_k127_1131113_43 MCRA family - - - 0.000000000000000000000000002759 112.0
CMS2_k127_1131113_44 - - - - 0.00000000000000000000000001717 119.0
CMS2_k127_1131113_45 - - - - 0.0000000000000000000002672 100.0
CMS2_k127_1131113_46 - - - - 0.0000000000000000000997 101.0
CMS2_k127_1131113_47 Thioredoxin K03671 - - 0.0000000000000000001688 93.0
CMS2_k127_1131113_48 Protein of unknown function (DUF2798) - - - 0.000000000000000004005 86.0
CMS2_k127_1131113_49 MCRA family K10254 - 4.2.1.53 0.00000000000003301 73.0
CMS2_k127_1131113_5 dehydrogenase K08325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 604.0
CMS2_k127_1131113_50 Histidine kinase K03407 - 2.7.13.3 0.0000000000203 72.0
CMS2_k127_1131113_51 GtrA-like protein - - - 0.0000000004959 65.0
CMS2_k127_1131113_52 - - - - 0.000000001977 70.0
CMS2_k127_1131113_53 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000002312 59.0
CMS2_k127_1131113_54 SNARE associated Golgi protein - - - 0.0000007649 56.0
CMS2_k127_1131113_55 SNARE associated Golgi protein - - - 0.00009981 49.0
CMS2_k127_1131113_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 608.0
CMS2_k127_1131113_7 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 583.0
CMS2_k127_1131113_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 492.0
CMS2_k127_1131113_9 Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) K00557 - 2.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 488.0
CMS2_k127_1148270_0 Cytochrome c - - - 1.119e-201 645.0
CMS2_k127_1148270_1 Bacterial protein of unknown function (DUF839) K07093 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 592.0
CMS2_k127_1148270_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 554.0
CMS2_k127_1148270_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001412 280.0
CMS2_k127_1148270_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001374 251.0
CMS2_k127_1148270_5 DoxX family K15977 - - 0.000000000000000000000000000000000000000000000000001241 186.0
CMS2_k127_1148270_6 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000001587 171.0
CMS2_k127_1148270_7 - - - - 0.00000000000000000000000000000006349 127.0
CMS2_k127_1169513_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 2.088e-254 790.0
CMS2_k127_1169513_1 Glycerol-3-phosphate dehydrogenase K11473 - - 2.029e-242 753.0
CMS2_k127_1169513_10 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000003618 166.0
CMS2_k127_1169513_11 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000006257 161.0
CMS2_k127_1169513_12 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000004214 147.0
CMS2_k127_1169513_13 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000005564 158.0
CMS2_k127_1169513_14 - - - - 0.0000000000001473 77.0
CMS2_k127_1169513_15 Belongs to the LOG family K06966 - 3.2.2.10 0.0000002114 52.0
CMS2_k127_1169513_2 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 480.0
CMS2_k127_1169513_3 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 355.0
CMS2_k127_1169513_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 298.0
CMS2_k127_1169513_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008875 276.0
CMS2_k127_1169513_6 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000000006919 200.0
CMS2_k127_1169513_7 Protein of unknown function (DUF3450) - - - 0.000000000000000000000000000000000000000000000000000000009016 207.0
CMS2_k127_1169513_8 PFAM DsrE DsrF-like family - - - 0.000000000000000000000000000000000000000000000006569 173.0
CMS2_k127_1169513_9 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000352 173.0
CMS2_k127_1191658_0 Protein of unknown function (DUF3604) - - - 0.0 1006.0
CMS2_k127_1191658_1 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 305.0
CMS2_k127_1191658_2 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004318 282.0
CMS2_k127_1191658_3 Transglutaminase-like superfamily K07184 - - 0.000000000000000000000000000000000000000000000000000000002827 214.0
CMS2_k127_1191658_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000003256 189.0
CMS2_k127_1191658_5 - - - - 0.000000000000000000000000000000000000000005481 161.0
CMS2_k127_1191658_6 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000002718 83.0
CMS2_k127_1197573_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0 1900.0
CMS2_k127_1197573_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1122.0
CMS2_k127_1197573_10 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 439.0
CMS2_k127_1197573_11 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 436.0
CMS2_k127_1197573_12 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 349.0
CMS2_k127_1197573_13 Serine hydrolase K07002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 297.0
CMS2_k127_1197573_14 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 297.0
CMS2_k127_1197573_15 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 285.0
CMS2_k127_1197573_16 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001613 265.0
CMS2_k127_1197573_17 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000008117 264.0
CMS2_k127_1197573_18 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003068 247.0
CMS2_k127_1197573_19 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.0000000000000000000000000000000000000000000000000000000000003767 224.0
CMS2_k127_1197573_2 Protein of unknown function (DUF1538) - - - 9.47e-297 921.0
CMS2_k127_1197573_20 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000001026 215.0
CMS2_k127_1197573_22 Thioredoxin K07396 - - 0.0000000000000000000000000000000000000001222 157.0
CMS2_k127_1197573_23 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 0.00000000000000000000000000000000000000185 161.0
CMS2_k127_1197573_24 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000007608 138.0
CMS2_k127_1197573_26 - - - - 0.0000000000000002952 81.0
CMS2_k127_1197573_27 AMIN domain - - - 0.0000000001367 71.0
CMS2_k127_1197573_28 LPP20 lipoprotein - - - 0.0000003099 63.0
CMS2_k127_1197573_29 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000005245 57.0
CMS2_k127_1197573_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 4.06e-246 763.0
CMS2_k127_1197573_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 599.0
CMS2_k127_1197573_5 Fad-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 598.0
CMS2_k127_1197573_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 513.0
CMS2_k127_1197573_7 pyridine nucleotide-disulfide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 487.0
CMS2_k127_1197573_8 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 493.0
CMS2_k127_1197573_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 485.0
CMS2_k127_1235178_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 2037.0
CMS2_k127_1235178_1 Belongs to the DNA mismatch repair MutS family K03555 - - 0.0 1513.0
CMS2_k127_1235178_10 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000001616 180.0
CMS2_k127_1235178_11 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000009443 179.0
CMS2_k127_1235178_2 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 1.095e-271 850.0
CMS2_k127_1235178_3 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 586.0
CMS2_k127_1235178_4 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 557.0
CMS2_k127_1235178_5 hmm pf00534 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 419.0
CMS2_k127_1235178_6 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 320.0
CMS2_k127_1235178_7 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 310.0
CMS2_k127_1235178_8 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000008105 235.0
CMS2_k127_1235178_9 signal transduction sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000005628 215.0
CMS2_k127_1321023_0 Heat shock 70 kDa protein K04043 - - 1.307e-266 833.0
CMS2_k127_1321023_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 452.0
CMS2_k127_1321023_10 Phosphopantetheine attachment site - - - 0.0000000000000000000000003417 107.0
CMS2_k127_1321023_11 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000002095 95.0
CMS2_k127_1321023_12 COG2931 RTX toxins and related Ca2 -binding proteins K01406,K07004 - 3.4.24.40 0.000000000000000003227 89.0
CMS2_k127_1321023_13 Protein of unknown function (DUF2905) - - - 0.0000000000000007663 79.0
CMS2_k127_1321023_14 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000001493 70.0
CMS2_k127_1321023_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 422.0
CMS2_k127_1321023_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000001251 269.0
CMS2_k127_1321023_4 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000001477 188.0
CMS2_k127_1321023_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000001418 183.0
CMS2_k127_1321023_6 COG1734 DnaK suppressor protein K06204 - - 0.0000000000000000000000000000000000002953 144.0
CMS2_k127_1321023_7 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000002139 134.0
CMS2_k127_1321023_8 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000000000001881 132.0
CMS2_k127_1321023_9 - - - - 0.000000000000000000000000001689 113.0
CMS2_k127_133414_0 Efflux pump membrane transporter K03296,K18138 - - 0.0 1489.0
CMS2_k127_133414_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 355.0
CMS2_k127_133414_2 RND efflux system, outer membrane lipoprotein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 308.0
CMS2_k127_133414_3 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000002118 182.0
CMS2_k127_133414_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000003194 96.0
CMS2_k127_133414_5 S4 domain K14761 - - 0.000000000000001988 81.0
CMS2_k127_14185_0 Receptor - - - 6.833e-238 744.0
CMS2_k127_14185_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 444.0
CMS2_k127_14185_10 Transcriptional regulator, ModE family K02019 - - 0.00000000000000000000000002878 113.0
CMS2_k127_14185_11 TOBE domain - - - 0.0000000000000000000002722 103.0
CMS2_k127_14185_2 - K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 415.0
CMS2_k127_14185_3 ATP-binding protein K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 385.0
CMS2_k127_14185_4 ABC transporter permease K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 360.0
CMS2_k127_14185_5 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 330.0
CMS2_k127_14185_6 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin K00477 - 1.14.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 312.0
CMS2_k127_14185_7 Belongs to the NadC ModD family K03813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004966 270.0
CMS2_k127_14185_8 N-terminal domain of molybdenum-binding protein K02019 - - 0.00000000000000000000000000000000000000000000000000000000000000000005932 241.0
CMS2_k127_14185_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000001097 142.0
CMS2_k127_1607758_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.009e-315 970.0
CMS2_k127_1607758_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.013e-312 971.0
CMS2_k127_1607758_10 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 343.0
CMS2_k127_1607758_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 338.0
CMS2_k127_1607758_12 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 335.0
CMS2_k127_1607758_13 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 323.0
CMS2_k127_1607758_14 Methyltransferase domain K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003176 281.0
CMS2_k127_1607758_15 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001269 269.0
CMS2_k127_1607758_16 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006418 253.0
CMS2_k127_1607758_17 Uncharacterized protein domain (DUF2202) - - - 0.0000000000000000000000000000000000000000000000000000000000001692 219.0
CMS2_k127_1607758_18 thiamine-phosphate diphosphorylase activity K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000002269 190.0
CMS2_k127_1607758_19 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000001067 177.0
CMS2_k127_1607758_2 Single-stranded-DNA-specific exonuclease (RecJ) K07462 - - 1.969e-201 640.0
CMS2_k127_1607758_20 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000000000000000000000000003646 151.0
CMS2_k127_1607758_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 599.0
CMS2_k127_1607758_4 Belongs to the UPF0324 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 512.0
CMS2_k127_1607758_5 COG0348 Polyferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 474.0
CMS2_k127_1607758_6 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 410.0
CMS2_k127_1607758_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 364.0
CMS2_k127_1607758_8 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 360.0
CMS2_k127_1607758_9 Abc transporter K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 347.0
CMS2_k127_161552_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 439.0
CMS2_k127_161552_1 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 362.0
CMS2_k127_161552_10 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000001642 178.0
CMS2_k127_161552_11 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000008627 117.0
CMS2_k127_161552_12 von Willebrand factor, type A K07114 - - 0.0000000000000000005461 97.0
CMS2_k127_161552_13 - - - - 0.0000000004015 66.0
CMS2_k127_161552_2 Receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 357.0
CMS2_k127_161552_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 317.0
CMS2_k127_161552_4 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 326.0
CMS2_k127_161552_5 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 306.0
CMS2_k127_161552_6 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004594 276.0
CMS2_k127_161552_7 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008042 248.0
CMS2_k127_161552_8 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.0000000000000000000000000000000000000000000000000000000000000002354 227.0
CMS2_k127_161552_9 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000000001322 203.0
CMS2_k127_1616592_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 3.821e-314 981.0
CMS2_k127_1616592_1 Belongs to the UbiD family K03182 - 4.1.1.98 8.989e-299 926.0
CMS2_k127_1616592_10 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 316.0
CMS2_k127_1616592_11 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005095 277.0
CMS2_k127_1616592_12 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002765 249.0
CMS2_k127_1616592_13 Hit family K02503 - - 0.0000000000000000000000000000000000000000000000000000002075 195.0
CMS2_k127_1616592_14 - - - - 0.0000000000000000000000000000000000003691 142.0
CMS2_k127_1616592_16 protein affecting phage T7 exclusion by the F plasmid K07113 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - 0.00009374 51.0
CMS2_k127_1616592_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 9.208e-282 874.0
CMS2_k127_1616592_3 argininosuccinate lyase K01755 - 4.3.2.1 1.169e-240 749.0
CMS2_k127_1616592_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 1.277e-203 642.0
CMS2_k127_1616592_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 575.0
CMS2_k127_1616592_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 458.0
CMS2_k127_1616592_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 426.0
CMS2_k127_1616592_8 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 420.0
CMS2_k127_1616592_9 ribosomal protein S1 K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 320.0
CMS2_k127_1639925_0 His Kinase A (phosphoacceptor) domain - - - 4.474e-240 760.0
CMS2_k127_1639925_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 605.0
CMS2_k127_1639925_10 Belongs to the mannose-6-phosphate isomerase type 2 family K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 301.0
CMS2_k127_1639925_11 GHKL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 320.0
CMS2_k127_1639925_12 PAS domain K03776 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001243 274.0
CMS2_k127_1639925_13 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001649 250.0
CMS2_k127_1639925_14 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000103 247.0
CMS2_k127_1639925_15 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001027 237.0
CMS2_k127_1639925_17 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000001234 198.0
CMS2_k127_1639925_18 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000005939 171.0
CMS2_k127_1639925_19 signal transduction sensor histidine kinase - - - 0.000000000000000000000000000000000000000001264 161.0
CMS2_k127_1639925_2 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 571.0
CMS2_k127_1639925_20 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000302 138.0
CMS2_k127_1639925_21 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000005813 140.0
CMS2_k127_1639925_22 - - - - 0.0000000000000000000000000000000008932 132.0
CMS2_k127_1639925_24 Hpt sensor hybrid histidine kinase - - - 0.0000003906 55.0
CMS2_k127_1639925_3 lipopolysaccharide heptosyltransferase K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 382.0
CMS2_k127_1639925_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 413.0
CMS2_k127_1639925_5 General glycosylation pathway protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 376.0
CMS2_k127_1639925_6 Two-component sensor histidine kinase response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 386.0
CMS2_k127_1639925_7 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 359.0
CMS2_k127_1639925_8 signal transduction response regulator (GGDEF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 361.0
CMS2_k127_1639925_9 FIST C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 338.0
CMS2_k127_1683350_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1016.0
CMS2_k127_1683350_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 8.206e-233 724.0
CMS2_k127_1683350_10 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001387 257.0
CMS2_k127_1683350_11 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000001605 226.0
CMS2_k127_1683350_12 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000001317 195.0
CMS2_k127_1683350_13 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000001111 188.0
CMS2_k127_1683350_14 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000001632 149.0
CMS2_k127_1683350_15 - - - - 0.00000003897 62.0
CMS2_k127_1683350_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 2.284e-227 707.0
CMS2_k127_1683350_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 602.0
CMS2_k127_1683350_4 ubiquinol cytochrome c oxidoreductase, cytochrome c1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 454.0
CMS2_k127_1683350_5 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 439.0
CMS2_k127_1683350_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 390.0
CMS2_k127_1683350_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 361.0
CMS2_k127_1683350_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 369.0
CMS2_k127_1683350_9 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001154 254.0
CMS2_k127_1898528_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 4.17e-295 918.0
CMS2_k127_1898528_1 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 401.0
CMS2_k127_1898528_2 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 315.0
CMS2_k127_1898528_3 Diguanylate cyclase phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000005213 226.0
CMS2_k127_1898528_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000002904 179.0
CMS2_k127_1898528_5 PFAM CHAD domain containing protein K08296 - - 0.0000000000000000000000000000002995 132.0
CMS2_k127_1898528_6 Domain of unknown function (DUF4156) - - - 0.000000000000000562 82.0
CMS2_k127_2039763_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1822.0
CMS2_k127_2039763_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1283.0
CMS2_k127_2039763_10 rod shape-determining protein mreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 602.0
CMS2_k127_2039763_11 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 605.0
CMS2_k127_2039763_12 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 553.0
CMS2_k127_2039763_13 phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 548.0
CMS2_k127_2039763_14 Co-chaperone-curved DNA binding protein A K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 435.0
CMS2_k127_2039763_15 COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 432.0
CMS2_k127_2039763_16 outer membrane porin, OprD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 433.0
CMS2_k127_2039763_17 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 422.0
CMS2_k127_2039763_18 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 439.0
CMS2_k127_2039763_19 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034,K12370 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 399.0
CMS2_k127_2039763_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1191.0
CMS2_k127_2039763_20 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 377.0
CMS2_k127_2039763_21 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 369.0
CMS2_k127_2039763_22 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 366.0
CMS2_k127_2039763_23 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 330.0
CMS2_k127_2039763_24 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 326.0
CMS2_k127_2039763_25 Pseudouridine synthase K06175 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 317.0
CMS2_k127_2039763_26 dna polymerase iii K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 308.0
CMS2_k127_2039763_27 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 299.0
CMS2_k127_2039763_28 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 301.0
CMS2_k127_2039763_29 AI-2E family transporter K11744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 301.0
CMS2_k127_2039763_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.142e-318 979.0
CMS2_k127_2039763_30 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001792 272.0
CMS2_k127_2039763_31 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002687 255.0
CMS2_k127_2039763_32 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000002333 244.0
CMS2_k127_2039763_33 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000139 264.0
CMS2_k127_2039763_34 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000363 235.0
CMS2_k127_2039763_35 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000002201 233.0
CMS2_k127_2039763_36 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000002946 228.0
CMS2_k127_2039763_37 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000003935 217.0
CMS2_k127_2039763_38 - - - - 0.000000000000000000000000000000000000000000000000000000000002258 214.0
CMS2_k127_2039763_39 MltA-interacting protein MipA K07274 - - 0.000000000000000000000000000000000000000000000000000000002839 209.0
CMS2_k127_2039763_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.831e-282 875.0
CMS2_k127_2039763_40 Transcriptional regulator K13640 - - 0.00000000000000000000000000000000000000000000000000000007429 197.0
CMS2_k127_2039763_41 Pentapeptide repeat - - - 0.00000000000000000000000000000000000000000000000000001621 195.0
CMS2_k127_2039763_42 Rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000000000002229 196.0
CMS2_k127_2039763_43 - - - - 0.000000000000000000000000000000000000000000000000001396 187.0
CMS2_k127_2039763_44 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000002316 180.0
CMS2_k127_2039763_45 Cupin domain - - - 0.0000000000000000000000000000000000000000000000004479 180.0
CMS2_k127_2039763_46 integral membrane protein - - - 0.000000000000000000000000000000000000000000000007498 180.0
CMS2_k127_2039763_47 Belongs to the 'phage' integrase family K14059 - - 0.000000000000000000000000000000000000000000003853 169.0
CMS2_k127_2039763_48 Histidine kinase K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000001751 175.0
CMS2_k127_2039763_49 COG0760 Parvulin-like peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000002217 150.0
CMS2_k127_2039763_5 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 6.054e-271 841.0
CMS2_k127_2039763_50 - - - - 0.0000000000000000000000000000000000000002657 151.0
CMS2_k127_2039763_51 membrane - - - 0.00000000000000000000000000000000000004817 145.0
CMS2_k127_2039763_52 L-threonylcarbamoyladenylate synthase - - - 0.000000000000000000000000000000000005021 142.0
CMS2_k127_2039763_53 Membrane - - - 0.000000000000000000000000000003586 128.0
CMS2_k127_2039763_54 fatty acid desaturase - - - 0.000000000000000000000000000004506 132.0
CMS2_k127_2039763_55 Polysaccharide deacetylase - - - 0.00000000000000000000000000009591 135.0
CMS2_k127_2039763_56 Transcriptional regulator - - - 0.0000000000000000000000001508 111.0
CMS2_k127_2039763_57 - - - - 0.000000308 53.0
CMS2_k127_2039763_58 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000109 56.0
CMS2_k127_2039763_6 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 5.872e-244 767.0
CMS2_k127_2039763_7 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.356e-223 697.0
CMS2_k127_2039763_8 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.677e-197 622.0
CMS2_k127_2039763_9 Glutathionylspermidine synthase - - - 7.299e-195 613.0
CMS2_k127_2047357_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 8.4e-323 1001.0
CMS2_k127_2047357_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 4.068e-210 658.0
CMS2_k127_2047357_10 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 323.0
CMS2_k127_2047357_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 302.0
CMS2_k127_2047357_12 GatB Yqey family protein K09117 - - 0.000000000000000000000000000000000000000000000000000001047 195.0
CMS2_k127_2047357_13 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000001955 188.0
CMS2_k127_2047357_14 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000000000000000000000000005542 187.0
CMS2_k127_2047357_15 Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000000000000000000000000001592 184.0
CMS2_k127_2047357_16 Thrombospondin type 3 repeat K03286 - - 0.00000000000000000000000000000000000003642 152.0
CMS2_k127_2047357_17 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000033 139.0
CMS2_k127_2047357_18 - - - - 0.0000000000000000000000000000000001003 139.0
CMS2_k127_2047357_19 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000002805 109.0
CMS2_k127_2047357_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 6.915e-201 629.0
CMS2_k127_2047357_20 PFAM PKD domain containing protein - - - 0.00000000000000000000003448 113.0
CMS2_k127_2047357_21 COG0659 Sulfate permease and related K03321 - - 0.0000000000000000000001136 97.0
CMS2_k127_2047357_22 PKD domain - - - 0.0000000000000000001902 102.0
CMS2_k127_2047357_23 GTP-binding protein K06207 - - 0.0000000000000009667 78.0
CMS2_k127_2047357_24 SpoIIAA-like - - - 0.0000001945 58.0
CMS2_k127_2047357_27 Domain of unknown function (DUF4386) - - - 0.000001536 51.0
CMS2_k127_2047357_3 Na Pi-cotransporter K03324 - - 9.706e-198 633.0
CMS2_k127_2047357_4 phosphohydrolase (DHH superfamily) K07097 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 532.0
CMS2_k127_2047357_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 452.0
CMS2_k127_2047357_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 405.0
CMS2_k127_2047357_7 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 381.0
CMS2_k127_2047357_8 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 328.0
CMS2_k127_2047357_9 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 333.0
CMS2_k127_2104879_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 1.915e-273 846.0
CMS2_k127_2104879_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 4.921e-256 793.0
CMS2_k127_2104879_10 Belongs to the AAA ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 554.0
CMS2_k127_2104879_11 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 490.0
CMS2_k127_2104879_12 Archaea bacterial proteins of unknown function K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 466.0
CMS2_k127_2104879_13 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 452.0
CMS2_k127_2104879_14 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 428.0
CMS2_k127_2104879_15 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 407.0
CMS2_k127_2104879_16 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 378.0
CMS2_k127_2104879_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 374.0
CMS2_k127_2104879_18 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 369.0
CMS2_k127_2104879_19 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 366.0
CMS2_k127_2104879_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 5.246e-245 759.0
CMS2_k127_2104879_20 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 367.0
CMS2_k127_2104879_21 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 361.0
CMS2_k127_2104879_22 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 351.0
CMS2_k127_2104879_23 RNase H K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 340.0
CMS2_k127_2104879_24 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006566 327.0
CMS2_k127_2104879_25 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 332.0
CMS2_k127_2104879_26 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 290.0
CMS2_k127_2104879_27 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001742 263.0
CMS2_k127_2104879_28 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004236 252.0
CMS2_k127_2104879_29 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000005285 253.0
CMS2_k127_2104879_3 anthranilate synthase component K01657 - 4.1.3.27 6.514e-227 710.0
CMS2_k127_2104879_30 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000009425 251.0
CMS2_k127_2104879_31 Belongs to the Fur family K03711 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000002204 241.0
CMS2_k127_2104879_32 UPF0313 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001845 228.0
CMS2_k127_2104879_33 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000000000000000000003945 232.0
CMS2_k127_2104879_34 - - - - 0.0000000000000000000000000000000000000000000000000000000001336 209.0
CMS2_k127_2104879_35 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.00000000000000000000000000000000000000000000000000000003563 199.0
CMS2_k127_2104879_36 Domain of unknown function (DUF1882) - - - 0.000000000000000000000000000000000000001015 154.0
CMS2_k127_2104879_37 ArsC family - - - 0.000000000000000000000000000000000000003072 148.0
CMS2_k127_2104879_38 - - - - 0.00000000000000000000000000000000000005573 145.0
CMS2_k127_2104879_39 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000005084 136.0
CMS2_k127_2104879_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 2.745e-212 663.0
CMS2_k127_2104879_40 Nitroreductase family - - - 0.00000000000000000000000000000000781 134.0
CMS2_k127_2104879_41 Cell division protein K03591,K03749 - - 0.0000000000000000000000000000004392 132.0
CMS2_k127_2104879_43 -acetyltransferase K06975 - - 0.0000000000000000000175 94.0
CMS2_k127_2104879_44 - - - - 0.00000000000001318 75.0
CMS2_k127_2104879_45 Protein of unknown function (DUF3293) - - - 0.0000000000103 71.0
CMS2_k127_2104879_5 MiaB-like tRNA modifying enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 604.0
CMS2_k127_2104879_6 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 592.0
CMS2_k127_2104879_7 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 588.0
CMS2_k127_2104879_8 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 579.0
CMS2_k127_2104879_9 domain protein K09944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 569.0
CMS2_k127_2143526_0 PFAM Alpha amylase, catalytic K00690 - 2.4.1.7 1.429e-240 756.0
CMS2_k127_2143526_1 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 589.0
CMS2_k127_2143526_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 366.0
CMS2_k127_2143526_3 hydroxypyruvate reductase K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 314.0
CMS2_k127_2161014_0 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 1.347e-255 795.0
CMS2_k127_2161014_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 2.018e-217 681.0
CMS2_k127_2161014_10 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 332.0
CMS2_k127_2161014_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 334.0
CMS2_k127_2161014_12 PFAM Ferredoxin thioredoxin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 301.0
CMS2_k127_2161014_13 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007225 254.0
CMS2_k127_2161014_15 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000000000000006892 237.0
CMS2_k127_2161014_16 COGs COG4087 Soluble P-type ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000006592 224.0
CMS2_k127_2161014_17 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000002293 196.0
CMS2_k127_2161014_18 COG1305 Transglutaminase-like enzymes K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000006427 192.0
CMS2_k127_2161014_19 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000000000000002055 171.0
CMS2_k127_2161014_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.446e-211 665.0
CMS2_k127_2161014_20 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000002178 169.0
CMS2_k127_2161014_21 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.00000000000000000000000000000000000001625 150.0
CMS2_k127_2161014_22 Heat shock protein DnaJ domain protein K06203,K07126 - - 0.00000000000000000000000000000000002148 137.0
CMS2_k127_2161014_23 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000004748 121.0
CMS2_k127_2161014_24 ATP synthase K02115 - - 0.00000000000000004234 92.0
CMS2_k127_2161014_25 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.00000000003904 68.0
CMS2_k127_2161014_26 ATP synthase B/B' CF(0) K02109 - - 0.0000003158 61.0
CMS2_k127_2161014_27 TIGRFAM F0F1-ATPase subunit K02116 - - 0.00003261 50.0
CMS2_k127_2161014_28 - - - - 0.00004207 51.0
CMS2_k127_2161014_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 578.0
CMS2_k127_2161014_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 565.0
CMS2_k127_2161014_5 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 520.0
CMS2_k127_2161014_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 496.0
CMS2_k127_2161014_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 468.0
CMS2_k127_2161014_8 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 464.0
CMS2_k127_2161014_9 PFAM Bacterial transcription activator, effector binding domain K13652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 450.0
CMS2_k127_2181721_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.157e-321 992.0
CMS2_k127_2181721_1 Atp-dependent helicase K03579 - 3.6.4.13 2.465e-284 896.0
CMS2_k127_2181721_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 323.0
CMS2_k127_2181721_11 Flagellar motor protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 324.0
CMS2_k127_2181721_12 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000195 278.0
CMS2_k127_2181721_13 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001412 271.0
CMS2_k127_2181721_14 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008992 241.0
CMS2_k127_2181721_15 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000001457 236.0
CMS2_k127_2181721_16 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000005597 229.0
CMS2_k127_2181721_17 Chemoreceptor zinc-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000002312 212.0
CMS2_k127_2181721_18 - - - - 0.00000000000000000000000000000000000000000000000001273 182.0
CMS2_k127_2181721_19 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000001484 183.0
CMS2_k127_2181721_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.878e-202 636.0
CMS2_k127_2181721_20 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000007167 154.0
CMS2_k127_2181721_21 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000004905 147.0
CMS2_k127_2181721_22 - - - - 0.0000000000000000000000000000000000005303 142.0
CMS2_k127_2181721_24 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.00000000000000000000000000000002451 142.0
CMS2_k127_2181721_25 - - - - 0.00000000000000003927 85.0
CMS2_k127_2181721_27 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0001071 44.0
CMS2_k127_2181721_3 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008444 632.0
CMS2_k127_2181721_4 PFAM TrkA-N domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 572.0
CMS2_k127_2181721_5 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 427.0
CMS2_k127_2181721_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 401.0
CMS2_k127_2181721_7 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 392.0
CMS2_k127_2181721_8 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 375.0
CMS2_k127_2181721_9 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 355.0
CMS2_k127_2282660_0 DNA polymerase X family K02347 - - 1.99e-204 651.0
CMS2_k127_2282660_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 289.0
CMS2_k127_2282660_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004648 283.0
CMS2_k127_2282660_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001643 263.0
CMS2_k127_2282660_4 Universal stress protein family - - - 0.0000002869 55.0
CMS2_k127_2282660_5 mechanosensitive ion channel - - - 0.000005945 49.0
CMS2_k127_23104_0 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0 1067.0
CMS2_k127_23104_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.036e-243 756.0
CMS2_k127_23104_10 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 321.0
CMS2_k127_23104_11 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000002206 235.0
CMS2_k127_23104_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000000000000000002899 176.0
CMS2_k127_23104_13 GlutRNAGln amidotransferase subunit D K01424 - 3.5.1.1 0.00000000000000000000000000000000000002257 150.0
CMS2_k127_23104_14 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000002409 151.0
CMS2_k127_23104_15 Cytochrome c553 K08738 - - 0.00000000000000000000000000000000002148 137.0
CMS2_k127_23104_16 O-acyltransferase activity K00661,K04042 - 2.3.1.157,2.3.1.79,2.7.7.23 0.0000000000000000000000000000002958 126.0
CMS2_k127_23104_17 peptide-methionine (S)-S-oxide reductase activity - - - 0.0000000000000000000000001509 108.0
CMS2_k127_23104_18 Cytochrome oxidase maturation protein - - - 0.0000000000000000000006325 96.0
CMS2_k127_23104_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 3.418e-223 705.0
CMS2_k127_23104_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 1.194e-215 682.0
CMS2_k127_23104_4 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 597.0
CMS2_k127_23104_5 ADP-L-glycero-D-manno-heptose-6-epimerase K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 558.0
CMS2_k127_23104_6 heptosyltransferase ii K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 453.0
CMS2_k127_23104_7 lipopolysaccharide core region biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 437.0
CMS2_k127_23104_8 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 412.0
CMS2_k127_23104_9 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0003674,GO:0005488,GO:0005515,GO:0042802 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 374.0
CMS2_k127_2337140_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 473.0
CMS2_k127_2337140_1 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 355.0
CMS2_k127_2337140_2 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000000000001292 177.0
CMS2_k127_2370812_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 - 2.7.7.6 0.0 2548.0
CMS2_k127_2370812_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2096.0
CMS2_k127_2370812_10 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 303.0
CMS2_k127_2370812_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 284.0
CMS2_k127_2370812_12 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000137 259.0
CMS2_k127_2370812_13 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001264 246.0
CMS2_k127_2370812_14 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003362 241.0
CMS2_k127_2370812_15 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000001609 196.0
CMS2_k127_2370812_16 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000005214 96.0
CMS2_k127_2370812_18 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000003016 71.0
CMS2_k127_2370812_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1266.0
CMS2_k127_2370812_3 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 1.996e-211 672.0
CMS2_k127_2370812_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 563.0
CMS2_k127_2370812_5 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 522.0
CMS2_k127_2370812_6 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 387.0
CMS2_k127_2370812_7 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 368.0
CMS2_k127_2370812_8 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 343.0
CMS2_k127_2370812_9 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 320.0
CMS2_k127_2372058_0 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 - - 3.519e-252 783.0
CMS2_k127_2372058_1 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 1.639e-194 619.0
CMS2_k127_2372058_10 Chorismate mutase K04782 - 4.2.99.21 0.0000000000000000000000000000000000187 137.0
CMS2_k127_2372058_11 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000009967 119.0
CMS2_k127_2372058_12 2'-5' RNA ligase K01975 - 3.1.4.58 0.000000000000000000000000000695 119.0
CMS2_k127_2372058_13 Rhodanese Homology Domain - - - 0.00000000000000000000000004819 115.0
CMS2_k127_2372058_14 Protein conserved in bacteria K09764 - - 0.000000000000000009357 86.0
CMS2_k127_2372058_2 COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 373.0
CMS2_k127_2372058_3 ABC transporter transmembrane region K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 363.0
CMS2_k127_2372058_4 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 313.0
CMS2_k127_2372058_5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000002072 244.0
CMS2_k127_2372058_6 PFAM O-methyltransferase, family 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001262 236.0
CMS2_k127_2372058_7 COG2199 FOG GGDEF domain - - - 0.000000000000000000000000000000000000000000006901 174.0
CMS2_k127_2372058_8 - - - - 0.0000000000000000000000000000000000000000009653 160.0
CMS2_k127_2372058_9 COG2166 SufE protein probably involved in Fe-S center assembly K02426 - - 0.0000000000000000000000000000000000000003229 153.0
CMS2_k127_2424977_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.989e-247 764.0
CMS2_k127_2424977_1 Belongs to the DNA photolyase family K01669 - 4.1.99.3 4.947e-202 638.0
CMS2_k127_2424977_10 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 424.0
CMS2_k127_2424977_11 Epimerase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 419.0
CMS2_k127_2424977_12 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 377.0
CMS2_k127_2424977_13 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 336.0
CMS2_k127_2424977_14 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 324.0
CMS2_k127_2424977_15 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 294.0
CMS2_k127_2424977_16 Fibronectin type 3 domain-containing protein K06882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006237 285.0
CMS2_k127_2424977_17 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.00000000000000000000000000000000000000000000000000000000001257 211.0
CMS2_k127_2424977_18 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000001014 204.0
CMS2_k127_2424977_19 - - - - 0.000000000000000000000000000000000000000000000000000002782 197.0
CMS2_k127_2424977_2 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 592.0
CMS2_k127_2424977_21 Cell division protein FtsX K09811 - - 0.000000000000000000000000000000000005253 148.0
CMS2_k127_2424977_22 - - - - 0.00000000000000000000000001963 110.0
CMS2_k127_2424977_23 - - - - 0.00003895 53.0
CMS2_k127_2424977_3 Pilus assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 591.0
CMS2_k127_2424977_4 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 550.0
CMS2_k127_2424977_5 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 484.0
CMS2_k127_2424977_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 477.0
CMS2_k127_2424977_7 na -driven multidrug efflux - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 463.0
CMS2_k127_2424977_8 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 455.0
CMS2_k127_2424977_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 429.0
CMS2_k127_2776941_0 DNA polymerase K02337 - 2.7.7.7 0.0 1980.0
CMS2_k127_2776941_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 4.054e-276 856.0
CMS2_k127_2776941_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 331.0
CMS2_k127_2776941_11 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000002572 247.0
CMS2_k127_2776941_12 - - - - 0.0000000000000000000000000000000000000000002731 161.0
CMS2_k127_2776941_13 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000002909 160.0
CMS2_k127_2776941_14 Protein required for attachment to host cells - - - 0.00000000000000000000000000000000005338 139.0
CMS2_k127_2776941_2 COG0841 Cation multidrug efflux pump - - - 2.307e-271 844.0
CMS2_k127_2776941_3 ribosomal protein S1 K02945 - - 1.229e-264 821.0
CMS2_k127_2776941_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 3.265e-263 818.0
CMS2_k127_2776941_5 Sulfatase - - - 2.454e-244 770.0
CMS2_k127_2776941_6 Radical SAM - - - 1.163e-206 654.0
CMS2_k127_2776941_7 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 592.0
CMS2_k127_2776941_8 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 455.0
CMS2_k127_2776941_9 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 344.0
CMS2_k127_2844021_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 4.716e-312 972.0
CMS2_k127_2844021_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 9.902e-236 746.0
CMS2_k127_2844021_10 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 426.0
CMS2_k127_2844021_11 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 411.0
CMS2_k127_2844021_12 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 398.0
CMS2_k127_2844021_13 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 389.0
CMS2_k127_2844021_14 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 361.0
CMS2_k127_2844021_15 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 340.0
CMS2_k127_2844021_16 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 324.0
CMS2_k127_2844021_17 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 309.0
CMS2_k127_2844021_18 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 292.0
CMS2_k127_2844021_19 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001012 266.0
CMS2_k127_2844021_2 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 582.0
CMS2_k127_2844021_20 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000135 203.0
CMS2_k127_2844021_21 COG1214 Inactive homolog of metal-dependent proteases - - - 0.00000000000000000000000000000000000000000000000000001359 193.0
CMS2_k127_2844021_22 Ferredoxin K05337 - - 0.0000000000000000000000000000000000000000168 153.0
CMS2_k127_2844021_23 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000001102 105.0
CMS2_k127_2844021_24 nucleic-acid-binding protein implicated in transcription termination - - - 0.0000000000000855 74.0
CMS2_k127_2844021_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 556.0
CMS2_k127_2844021_4 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 520.0
CMS2_k127_2844021_5 peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 524.0
CMS2_k127_2844021_6 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 511.0
CMS2_k127_2844021_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 481.0
CMS2_k127_2844021_8 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 480.0
CMS2_k127_2844021_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009082 427.0
CMS2_k127_2861808_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 9.684e-221 690.0
CMS2_k127_2861808_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 359.0
CMS2_k127_2861808_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 313.0
CMS2_k127_2861808_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000001686 243.0
CMS2_k127_2861808_4 Cytochrome c - - - 0.0000000000000000000000000000003241 125.0
CMS2_k127_2993049_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1097.0
CMS2_k127_2993049_1 Protein of unknown function (DUF3373) - - - 2.103e-200 637.0
CMS2_k127_2993049_10 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.000000000000000000000000000001777 122.0
CMS2_k127_2993049_11 RESPONSE REGULATOR receiver K07288 - - 0.00000000000000002963 92.0
CMS2_k127_2993049_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 476.0
CMS2_k127_2993049_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 428.0
CMS2_k127_2993049_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 323.0
CMS2_k127_2993049_5 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 302.0
CMS2_k127_2993049_6 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 294.0
CMS2_k127_2993049_7 nucleotide-binding protein implicated in inhibition of septum formation K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003113 257.0
CMS2_k127_2993049_8 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000001648 205.0
CMS2_k127_2993049_9 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000001964 191.0
CMS2_k127_301008_0 Efflux pump membrane transporter K03296,K18138 - - 0.0 1500.0
CMS2_k127_301008_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1481.0
CMS2_k127_301008_10 HD domain - - - 5.075e-223 715.0
CMS2_k127_301008_11 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 1.846e-222 700.0
CMS2_k127_301008_12 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 4.464e-215 674.0
CMS2_k127_301008_13 Mg chelatase-related protein K07391 - - 1.439e-207 656.0
CMS2_k127_301008_14 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 592.0
CMS2_k127_301008_15 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 585.0
CMS2_k127_301008_16 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 589.0
CMS2_k127_301008_17 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 575.0
CMS2_k127_301008_18 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 567.0
CMS2_k127_301008_19 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 555.0
CMS2_k127_301008_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0 1129.0
CMS2_k127_301008_20 NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 524.0
CMS2_k127_301008_21 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 477.0
CMS2_k127_301008_22 general secretion pathway protein D K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 428.0
CMS2_k127_301008_23 COG1459 Type II secretory pathway, component PulF K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 412.0
CMS2_k127_301008_24 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 379.0
CMS2_k127_301008_25 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 376.0
CMS2_k127_301008_26 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 372.0
CMS2_k127_301008_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 375.0
CMS2_k127_301008_28 RND efflux system, outer membrane lipoprotein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 366.0
CMS2_k127_301008_29 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 351.0
CMS2_k127_301008_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1090.0
CMS2_k127_301008_30 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 330.0
CMS2_k127_301008_31 GTP cyclohydrolase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 325.0
CMS2_k127_301008_32 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 295.0
CMS2_k127_301008_33 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 284.0
CMS2_k127_301008_34 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 283.0
CMS2_k127_301008_35 PFAM Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000129 254.0
CMS2_k127_301008_36 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002157 251.0
CMS2_k127_301008_37 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000001283 226.0
CMS2_k127_301008_38 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001818 249.0
CMS2_k127_301008_39 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000006311 215.0
CMS2_k127_301008_4 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03455,K11747 - - 3.479e-250 782.0
CMS2_k127_301008_40 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000003242 192.0
CMS2_k127_301008_41 Belongs to the globin family K05916 - 1.14.12.17 0.000000000000000000000000000000000000000000000000000004632 193.0
CMS2_k127_301008_42 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000216 181.0
CMS2_k127_301008_43 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000249 181.0
CMS2_k127_301008_44 YceI-like domain - - - 0.000000000000000000000000000000000000000000000002126 180.0
CMS2_k127_301008_45 Transcriptional regulator K03892 - - 0.0000000000000000000000000000000000000000000006109 168.0
CMS2_k127_301008_46 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000003009 139.0
CMS2_k127_301008_47 - - - - 0.0000000000000000000000000000000756 136.0
CMS2_k127_301008_48 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000001204 106.0
CMS2_k127_301008_49 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000001299 112.0
CMS2_k127_301008_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 4.07e-247 773.0
CMS2_k127_301008_50 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.15.1.1 0.00000000000000000000008835 100.0
CMS2_k127_301008_51 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000001663 103.0
CMS2_k127_301008_52 - - - - 0.0000000000000003092 89.0
CMS2_k127_301008_53 - - - - 0.000000000000000749 84.0
CMS2_k127_301008_54 proline dehydrogenase activity - - - 0.000000000005452 77.0
CMS2_k127_301008_55 Prokaryotic N-terminal methylation motif - - - 0.000000006148 63.0
CMS2_k127_301008_56 - - - - 0.00000001192 64.0
CMS2_k127_301008_57 - - - - 0.00000001825 62.0
CMS2_k127_301008_58 - - - - 0.0000001088 56.0
CMS2_k127_301008_6 Cysteine desulfurase K04487 - 2.8.1.7 4.62e-236 733.0
CMS2_k127_301008_7 Cytochrome c oxidase accessory protein - - - 3.779e-230 728.0
CMS2_k127_301008_8 pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 2.105e-229 719.0
CMS2_k127_301008_9 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.096e-224 701.0
CMS2_k127_3139263_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.5.1 0.0 1017.0
CMS2_k127_3139263_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 2.913e-313 975.0
CMS2_k127_3139263_10 hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 311.0
CMS2_k127_3139263_11 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002153 279.0
CMS2_k127_3139263_12 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide - - - 0.0000000000000000000000000000000000000000000002202 188.0
CMS2_k127_3139263_13 hydrogenase assembly chaperone HypC K04653 - - 0.00000000000000000000000000000000000001452 145.0
CMS2_k127_3139263_2 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 8e-310 953.0
CMS2_k127_3139263_3 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 2.63e-306 944.0
CMS2_k127_3139263_4 Small subunit K05927 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.5.1 9.912e-230 715.0
CMS2_k127_3139263_5 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 6.735e-201 631.0
CMS2_k127_3139263_6 Belongs to the HypD family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 607.0
CMS2_k127_3139263_7 Hydrogenase K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 441.0
CMS2_k127_3139263_8 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 374.0
CMS2_k127_3139263_9 Ni Fe-hydrogenase, b-type cytochrome subunit K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 349.0
CMS2_k127_3146880_0 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 0.0 1588.0
CMS2_k127_3146880_1 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 6.29e-321 988.0
CMS2_k127_3146880_10 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009678 526.0
CMS2_k127_3146880_11 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 481.0
CMS2_k127_3146880_12 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 481.0
CMS2_k127_3146880_13 PFAM SufBD protein K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 419.0
CMS2_k127_3146880_14 ABC transporter, ATP-binding protein K01990,K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 398.0
CMS2_k127_3146880_15 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 403.0
CMS2_k127_3146880_16 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 378.0
CMS2_k127_3146880_17 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 382.0
CMS2_k127_3146880_18 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 355.0
CMS2_k127_3146880_2 acetolactate synthase K01652 - 2.2.1.6 1.935e-315 973.0
CMS2_k127_3146880_20 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 343.0
CMS2_k127_3146880_21 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 302.0
CMS2_k127_3146880_22 tigr02757 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 290.0
CMS2_k127_3146880_23 Histidine kinase A domain protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002428 308.0
CMS2_k127_3146880_25 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004236 282.0
CMS2_k127_3146880_26 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000017 271.0
CMS2_k127_3146880_27 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000474 264.0
CMS2_k127_3146880_28 MafB19-like deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001615 252.0
CMS2_k127_3146880_29 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003923 261.0
CMS2_k127_3146880_3 arginine decarboxylase K01585 - 4.1.1.19 1.308e-295 916.0
CMS2_k127_3146880_30 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000001495 238.0
CMS2_k127_3146880_31 acetolactate synthase K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000006649 228.0
CMS2_k127_3146880_32 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000006006 222.0
CMS2_k127_3146880_33 Phospholipid methyltransferase K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000002482 216.0
CMS2_k127_3146880_34 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000001102 208.0
CMS2_k127_3146880_35 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000005214 212.0
CMS2_k127_3146880_36 - - - - 0.00000000000000000000000000000000000000000000000000001591 194.0
CMS2_k127_3146880_37 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000000000000000167 189.0
CMS2_k127_3146880_38 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.000000000000000000000000000000000000000000000003501 186.0
CMS2_k127_3146880_39 Staphylococcal nuclease homologue - - - 0.00000000000000000000000000000000000000000000002847 174.0
CMS2_k127_3146880_4 Belongs to the FtsK SpoIIIE SftA family K03466 - - 4.312e-289 906.0
CMS2_k127_3146880_40 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.00000000000000000000000000000000000000005045 172.0
CMS2_k127_3146880_41 Cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000003042 150.0
CMS2_k127_3146880_42 ATPase or kinase K06925 - - 0.00000000000000000000000000000000000001443 149.0
CMS2_k127_3146880_43 Cytochrome P460 - - - 0.00000000000000000000000000000000000001814 149.0
CMS2_k127_3146880_44 - - - - 0.0000000000000000000000000000000001437 135.0
CMS2_k127_3146880_45 S4 domain protein - - - 0.000000000000000000000000000009929 119.0
CMS2_k127_3146880_46 - - - - 0.000000000000000000000000007894 110.0
CMS2_k127_3146880_47 BPTI/Kunitz family of serine protease inhibitors. - - - 0.0000004134 59.0
CMS2_k127_3146880_48 Belongs to the 'phage' integrase family K03111 - - 0.0002356 43.0
CMS2_k127_3146880_49 - - - - 0.0007838 48.0
CMS2_k127_3146880_5 Aminotransferase K00812 - 2.6.1.1 9.629e-201 630.0
CMS2_k127_3146880_6 histidyl-tRNA synthetase K01892 - 6.1.1.21 2.369e-195 615.0
CMS2_k127_3146880_7 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 586.0
CMS2_k127_3146880_8 Heterodisulfide reductase subunit B K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 577.0
CMS2_k127_3146880_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 580.0
CMS2_k127_3173402_0 Belongs to the 5'-nucleotidase family K01119,K17224 - 3.1.3.6,3.1.4.16 0.0 1073.0
CMS2_k127_3173402_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 9.12e-273 843.0
CMS2_k127_3173402_10 phosphorelay sensor kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 358.0
CMS2_k127_3173402_11 component of anaerobic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 301.0
CMS2_k127_3173402_12 sensor protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001819 258.0
CMS2_k127_3173402_13 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002575 250.0
CMS2_k127_3173402_14 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000002716 229.0
CMS2_k127_3173402_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004234 223.0
CMS2_k127_3173402_16 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000000000005198 211.0
CMS2_k127_3173402_17 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.0000000000000000000000000000000000000000000000000000001522 203.0
CMS2_k127_3173402_18 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000009879 188.0
CMS2_k127_3173402_19 oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000000000000007595 162.0
CMS2_k127_3173402_2 diguanylate cyclase - - - 9.325e-250 784.0
CMS2_k127_3173402_20 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000005077 162.0
CMS2_k127_3173402_21 - - - - 0.00000000000000000000000000000000000000006665 153.0
CMS2_k127_3173402_22 Receptor - - - 0.000000000000007679 76.0
CMS2_k127_3173402_23 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000001938 66.0
CMS2_k127_3173402_24 Transcriptional regulatory protein, C terminal K07775 - - 0.00000009293 63.0
CMS2_k127_3173402_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 1.403e-218 681.0
CMS2_k127_3173402_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.005e-202 631.0
CMS2_k127_3173402_5 sulfate adenylyltransferase K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 595.0
CMS2_k127_3173402_6 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 490.0
CMS2_k127_3173402_7 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 483.0
CMS2_k127_3173402_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 470.0
CMS2_k127_3173402_9 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 389.0
CMS2_k127_3243402_0 COGs COG0647 sugar phosphatase of the HAD superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 320.0
CMS2_k127_3243402_1 Double sensory domain of two-component sensor kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 311.0
CMS2_k127_3243402_10 Histidine kinase A domain protein - - - 0.000000000000000000000000007313 127.0
CMS2_k127_3243402_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001136 218.0
CMS2_k127_3243402_3 - - - - 0.00000000000000000000000000000000000000000000000000000000001066 209.0
CMS2_k127_3243402_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000008104 207.0
CMS2_k127_3243402_6 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000003316 169.0
CMS2_k127_3243402_7 Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO K21694 - - 0.0000000000000000000000000000000000000001197 153.0
CMS2_k127_3243402_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000003291 154.0
CMS2_k127_324367_0 glutamine synthetase K01915 - 6.3.1.2 2.967e-293 903.0
CMS2_k127_324367_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 6.532e-288 891.0
CMS2_k127_324367_10 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000001938 249.0
CMS2_k127_324367_11 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000002179 209.0
CMS2_k127_324367_12 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000001805 136.0
CMS2_k127_324367_14 Immune inhibitor A peptidase M6 - - - 0.0000001134 58.0
CMS2_k127_324367_2 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 3.754e-258 814.0
CMS2_k127_324367_3 peptidase U32 family K08303 - - 5.345e-230 717.0
CMS2_k127_324367_4 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 378.0
CMS2_k127_324367_5 histidinol phosphate phosphatase K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 372.0
CMS2_k127_324367_6 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 356.0
CMS2_k127_324367_7 abc transporter atp-binding protein K02031,K15587 - 3.6.3.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 308.0
CMS2_k127_324367_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 283.0
CMS2_k127_324367_9 GHKL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007446 256.0
CMS2_k127_3283153_0 Cytochrome c554 and c-prime - - - 2.087e-274 861.0
CMS2_k127_3283153_1 Cache domain - - - 1.02e-268 833.0
CMS2_k127_3283153_10 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 313.0
CMS2_k127_3283153_11 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 294.0
CMS2_k127_3283153_12 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003217 277.0
CMS2_k127_3283153_13 Ndr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006787 278.0
CMS2_k127_3283153_14 Exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000361 261.0
CMS2_k127_3283153_16 PFAM LrgB family protein - - - 0.0000000000000000000000000000000000000000000000000007583 195.0
CMS2_k127_3283153_18 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000006811 161.0
CMS2_k127_3283153_2 PFAM Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 515.0
CMS2_k127_3283153_20 Bacterial transcription activator, effector binding domain - - - 0.0000000000000000000000000001649 121.0
CMS2_k127_3283153_22 LrgA family K06518 - - 0.0000000000000000005717 91.0
CMS2_k127_3283153_24 - - - - 0.000000000295 70.0
CMS2_k127_3283153_3 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 486.0
CMS2_k127_3283153_4 Epimerase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 469.0
CMS2_k127_3283153_5 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 432.0
CMS2_k127_3283153_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 386.0
CMS2_k127_3283153_7 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 334.0
CMS2_k127_3283153_8 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 335.0
CMS2_k127_3283153_9 Dtw domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 323.0
CMS2_k127_3392019_0 ATP-dependent DNA helicase K03655 - 3.6.4.12 1.299e-225 717.0
CMS2_k127_3392019_1 Prepilin-type N-terminal cleavage methylation domain - - - 0.000000000000000000000000000000000000000000000000000000000003782 218.0
CMS2_k127_3392019_2 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.0000000000000000000000000000000000000000000000000000000002809 207.0
CMS2_k127_3392019_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000003484 114.0
CMS2_k127_3392019_4 - - - - 0.0000000000000000000002858 104.0
CMS2_k127_3392019_5 general secretion pathway protein - - - 0.000000000000000000001051 103.0
CMS2_k127_3392019_6 Hep Hag repeat protein - - - 0.000001378 53.0
CMS2_k127_3465906_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1487.0
CMS2_k127_3465906_1 ABC transporter, ATP-binding protein K15738 - - 4.051e-315 975.0
CMS2_k127_3465906_10 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 7.906e-199 624.0
CMS2_k127_3465906_11 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.442e-195 616.0
CMS2_k127_3465906_12 transporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 604.0
CMS2_k127_3465906_13 potassium channel protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 564.0
CMS2_k127_3465906_14 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 555.0
CMS2_k127_3465906_15 PFAM HI0933 family protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 551.0
CMS2_k127_3465906_16 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 539.0
CMS2_k127_3465906_17 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 467.0
CMS2_k127_3465906_18 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 428.0
CMS2_k127_3465906_19 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 409.0
CMS2_k127_3465906_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.207e-312 967.0
CMS2_k127_3465906_20 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 390.0
CMS2_k127_3465906_21 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 378.0
CMS2_k127_3465906_22 hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 355.0
CMS2_k127_3465906_23 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 359.0
CMS2_k127_3465906_24 asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 367.0
CMS2_k127_3465906_25 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 344.0
CMS2_k127_3465906_26 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 332.0
CMS2_k127_3465906_27 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 297.0
CMS2_k127_3465906_28 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003257 282.0
CMS2_k127_3465906_29 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008258 247.0
CMS2_k127_3465906_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 4.594e-297 927.0
CMS2_k127_3465906_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000002685 221.0
CMS2_k127_3465906_31 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000009014 220.0
CMS2_k127_3465906_32 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000002847 210.0
CMS2_k127_3465906_33 - - - - 0.00000000000000000000000000000000000000000000000000000008406 205.0
CMS2_k127_3465906_34 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000002838 197.0
CMS2_k127_3465906_35 Hemolysin K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000003145 196.0
CMS2_k127_3465906_36 RDD family - - - 0.000000000000000000000000000000000000000000000000001586 191.0
CMS2_k127_3465906_37 TrkA-N domain K10716 - - 0.00000000000000000000000000000000000000000002417 169.0
CMS2_k127_3465906_38 membrane - - - 0.0000000000000000000000000000000000000004703 153.0
CMS2_k127_3465906_39 Stress responsive A B Barrel Domain - - - 0.0000000000000000000000000000007996 124.0
CMS2_k127_3465906_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.296e-250 777.0
CMS2_k127_3465906_40 - - - - 0.0000000000000000000000000001221 119.0
CMS2_k127_3465906_41 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000000000005278 112.0
CMS2_k127_3465906_42 cytochrome - - - 0.0000000000000000000002292 104.0
CMS2_k127_3465906_43 - - - - 0.00000000000000000000128 99.0
CMS2_k127_3465906_44 - - - - 0.0000000000000000002762 88.0
CMS2_k127_3465906_48 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000006977 73.0
CMS2_k127_3465906_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 3.422e-249 775.0
CMS2_k127_3465906_51 - - - - 0.000009793 48.0
CMS2_k127_3465906_6 ABC-type multidrug transport system ATPase and permease - - - 8.914e-245 769.0
CMS2_k127_3465906_7 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.067e-234 730.0
CMS2_k127_3465906_8 o-acetylhomoserine K01740 - 2.5.1.49 6.744e-221 690.0
CMS2_k127_3465906_9 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 2.246e-208 657.0
CMS2_k127_3482003_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.803e-238 739.0
CMS2_k127_3482003_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.395e-195 620.0
CMS2_k127_3482003_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 457.0
CMS2_k127_3482003_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008228 269.0
CMS2_k127_3482003_4 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003951 265.0
CMS2_k127_3482003_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003876 248.0
CMS2_k127_3482003_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000805 223.0
CMS2_k127_3482003_7 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000003558 209.0
CMS2_k127_3500982_0 Acts as a magnesium transporter K06213 - - 2.616e-216 678.0
CMS2_k127_3500982_1 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 573.0
CMS2_k127_3500982_2 Domain of unknown function (DUF389) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 569.0
CMS2_k127_3500982_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 293.0
CMS2_k127_3500982_4 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008534 270.0
CMS2_k127_3500982_5 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000003621 156.0
CMS2_k127_3500982_6 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000000001782 147.0
CMS2_k127_3526553_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1425.0
CMS2_k127_3526553_1 GTP-binding protein K06207 - - 0.0 1062.0
CMS2_k127_3526553_10 Belongs to the pseudouridine synthase RluA family K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 419.0
CMS2_k127_3526553_11 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 374.0
CMS2_k127_3526553_12 COG0642 Signal transduction histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 321.0
CMS2_k127_3526553_13 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 306.0
CMS2_k127_3526553_14 phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 304.0
CMS2_k127_3526553_16 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005012 259.0
CMS2_k127_3526553_17 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001557 229.0
CMS2_k127_3526553_18 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000002335 203.0
CMS2_k127_3526553_19 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000003666 184.0
CMS2_k127_3526553_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.228e-270 834.0
CMS2_k127_3526553_20 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000001209 169.0
CMS2_k127_3526553_21 Cytochrome c - - - 0.00000000000000000000000000000000000000000002856 165.0
CMS2_k127_3526553_22 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000002289 156.0
CMS2_k127_3526553_23 - - - - 0.00000000000000000000000000001303 120.0
CMS2_k127_3526553_24 - - - - 0.0000000000000000000000000002108 118.0
CMS2_k127_3526553_25 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000000000000000000003046 97.0
CMS2_k127_3526553_26 - - - - 0.0000000000000000000003444 97.0
CMS2_k127_3526553_27 - - - - 0.0000000000009776 70.0
CMS2_k127_3526553_29 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000001254 58.0
CMS2_k127_3526553_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.088e-264 825.0
CMS2_k127_3526553_4 Phospholipid glycerol acyltransferase - - - 2.272e-233 735.0
CMS2_k127_3526553_5 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 604.0
CMS2_k127_3526553_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 589.0
CMS2_k127_3526553_7 Belongs to the UPF0061 (SELO) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 561.0
CMS2_k127_3526553_8 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 471.0
CMS2_k127_3526553_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 444.0
CMS2_k127_3569569_0 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 301.0
CMS2_k127_3569569_1 Hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000005335 185.0
CMS2_k127_3621354_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 484.0
CMS2_k127_3621354_1 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 448.0
CMS2_k127_3621354_10 sodium:proton antiporter activity K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 302.0
CMS2_k127_3621354_11 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003095 274.0
CMS2_k127_3621354_12 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001839 276.0
CMS2_k127_3621354_13 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009815 269.0
CMS2_k127_3621354_14 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004876 241.0
CMS2_k127_3621354_15 MotA TolQ ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003904 233.0
CMS2_k127_3621354_16 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000351 228.0
CMS2_k127_3621354_17 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000000000000000000000000007162 224.0
CMS2_k127_3621354_18 hmm pf01205 - - - 0.0000000000000000000000000000000000000000000000000000000001779 208.0
CMS2_k127_3621354_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000001034 188.0
CMS2_k127_3621354_2 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 441.0
CMS2_k127_3621354_20 transport protein K03559 - - 0.0000000000000000000000000000000000000000000000004341 178.0
CMS2_k127_3621354_21 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000139 176.0
CMS2_k127_3621354_22 Bacterial protein of unknown function (YtfJ_HI0045) K07109 - - 0.00000000000000000000000000000000000000000000001804 175.0
CMS2_k127_3621354_23 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000001016 147.0
CMS2_k127_3621354_24 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000003292 131.0
CMS2_k127_3621354_25 TonB C terminal K03832 - - 0.000000000000000000000000000000001717 139.0
CMS2_k127_3621354_26 - - - - 0.0000000000000000000000000000001968 128.0
CMS2_k127_3621354_27 Rhodanese-like domain - - - 0.00000000000000000000000001495 112.0
CMS2_k127_3621354_28 OmpA-like transmembrane domain - - - 0.00000000000000000000008058 106.0
CMS2_k127_3621354_29 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00001719 46.0
CMS2_k127_3621354_3 Belongs to the TtcA family K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 415.0
CMS2_k127_3621354_4 Protein of unknown function (DUF3137) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 376.0
CMS2_k127_3621354_5 a g-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 374.0
CMS2_k127_3621354_6 membrane K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 370.0
CMS2_k127_3621354_7 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K18284 - 3.2.2.30,3.2.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 345.0
CMS2_k127_3621354_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 324.0
CMS2_k127_3621354_9 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 306.0
CMS2_k127_370447_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 5.296e-226 703.0
CMS2_k127_370447_1 2-acylglycerophosphoethanolamine acyltransferase K05939 - 2.3.1.40,6.2.1.20 6.856e-197 632.0
CMS2_k127_370447_10 - - - - 0.000000000000000000000000000007891 124.0
CMS2_k127_370447_11 Domain of unknown function (DUF1851) - - - 0.00000000000000000000000000001582 123.0
CMS2_k127_370447_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000001391 120.0
CMS2_k127_370447_13 - - - - 0.00000000000000000000002374 111.0
CMS2_k127_370447_14 Protein of unknown function (DUF2892) - - - 0.000000000000000000002938 94.0
CMS2_k127_370447_15 Ppx GppA phosphatase - - - 0.000000246 59.0
CMS2_k127_370447_16 von Willebrand factor (vWF) type A domain K20478 - - 0.0000002594 63.0
CMS2_k127_370447_2 Pfam Transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 374.0
CMS2_k127_370447_3 Di-haem cytochrome c peroxidase - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 338.0
CMS2_k127_370447_4 PFAM Flavin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 316.0
CMS2_k127_370447_5 Family of unknown function (DUF695) - - - 0.000000000000000000000000000000000000000000000000000003365 198.0
CMS2_k127_370447_6 - - - - 0.0000000000000000000000000000000000000001086 157.0
CMS2_k127_370447_7 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000004811 151.0
CMS2_k127_370447_8 FMN binding - - - 0.000000000000000000000000000000000000008139 152.0
CMS2_k127_370447_9 - - - - 0.000000000000000000000000000004183 124.0
CMS2_k127_3804752_0 - - - - 0.0 1236.0
CMS2_k127_3804752_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 3.712e-291 907.0
CMS2_k127_3804752_10 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 555.0
CMS2_k127_3804752_11 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 553.0
CMS2_k127_3804752_12 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 528.0
CMS2_k127_3804752_13 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 509.0
CMS2_k127_3804752_14 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 497.0
CMS2_k127_3804752_15 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 480.0
CMS2_k127_3804752_16 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 474.0
CMS2_k127_3804752_17 dehydrogenase K00076 - 1.1.1.159 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 456.0
CMS2_k127_3804752_18 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 439.0
CMS2_k127_3804752_19 Magnesium transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 434.0
CMS2_k127_3804752_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.802e-224 703.0
CMS2_k127_3804752_20 COGs COG0665 Glycine D-amino acid oxidase (deaminating) K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 413.0
CMS2_k127_3804752_21 leucine binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 402.0
CMS2_k127_3804752_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 388.0
CMS2_k127_3804752_23 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 377.0
CMS2_k127_3804752_24 Glycosyl hydrolase family 3 K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 347.0
CMS2_k127_3804752_25 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 333.0
CMS2_k127_3804752_26 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 338.0
CMS2_k127_3804752_27 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 330.0
CMS2_k127_3804752_28 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 325.0
CMS2_k127_3804752_29 leucine binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 327.0
CMS2_k127_3804752_3 Belongs to the peptidase M16 family - - - 6.166e-208 668.0
CMS2_k127_3804752_30 with different specificities (related to short-chain alcohol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 308.0
CMS2_k127_3804752_31 NUDIX domain K16855 - 3.6.1.62,3.6.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 304.0
CMS2_k127_3804752_32 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 302.0
CMS2_k127_3804752_33 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 305.0
CMS2_k127_3804752_34 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 286.0
CMS2_k127_3804752_35 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004469 279.0
CMS2_k127_3804752_36 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006462 275.0
CMS2_k127_3804752_37 HIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007803 269.0
CMS2_k127_3804752_38 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000007481 264.0
CMS2_k127_3804752_39 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005593 256.0
CMS2_k127_3804752_4 HI0933-like protein K07007 - - 6.241e-208 653.0
CMS2_k127_3804752_40 COG1881 Phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001633 256.0
CMS2_k127_3804752_41 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000006195 250.0
CMS2_k127_3804752_42 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000006856 254.0
CMS2_k127_3804752_43 COG4464 Capsular polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008641 256.0
CMS2_k127_3804752_44 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000001947 219.0
CMS2_k127_3804752_45 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000000000000001229 201.0
CMS2_k127_3804752_46 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.00000000000000000000000000000000000000000000000003405 183.0
CMS2_k127_3804752_47 thioesterase K07107 - - 0.000000000000000000000000000000000000000000152 162.0
CMS2_k127_3804752_48 alpha beta K06889 - - 0.000000000000000000000000000000000000000002098 168.0
CMS2_k127_3804752_49 Membrane K08988 - - 0.0000000000000000000000000000000000000001133 159.0
CMS2_k127_3804752_5 domain, Protein - - - 1.089e-201 644.0
CMS2_k127_3804752_50 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000204 149.0
CMS2_k127_3804752_51 - - - - 0.000000000000000000000000000000000007869 141.0
CMS2_k127_3804752_52 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000004247 140.0
CMS2_k127_3804752_53 Belongs to the ompA family K03286 - - 0.000000000000000000000000000001262 134.0
CMS2_k127_3804752_54 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000002597 111.0
CMS2_k127_3804752_55 Domain of unknown function (DUF4234) - - - 0.000000000000000000001579 104.0
CMS2_k127_3804752_57 Domain of unknown function (DUF4136) - - - 0.00000003359 62.0
CMS2_k127_3804752_6 Mur ligase middle domain K01929 - 6.3.2.10 5.61e-201 635.0
CMS2_k127_3804752_60 Right handed beta helix region - - - 0.0002394 53.0
CMS2_k127_3804752_61 helix_turn_helix, mercury resistance - - - 0.0002641 50.0
CMS2_k127_3804752_7 TRAP transporter, DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 604.0
CMS2_k127_3804752_8 Major Facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 580.0
CMS2_k127_3804752_9 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 580.0
CMS2_k127_3919297_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1030.0
CMS2_k127_3919297_1 Polysaccharide biosynthesis protein K15912 - 4.2.1.135 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 536.0
CMS2_k127_3919297_2 - - - - 0.000000004153 61.0
CMS2_k127_3919297_3 Transposase - - - 0.000003978 51.0
CMS2_k127_3963187_0 Highly conserved protein containing a thioredoxin domain K06888 - - 1.337e-252 794.0
CMS2_k127_3963187_1 threonine synthase K01733 - 4.2.3.1 1.18e-246 769.0
CMS2_k127_3963187_10 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 407.0
CMS2_k127_3963187_11 hmm pf04305 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 366.0
CMS2_k127_3963187_12 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 366.0
CMS2_k127_3963187_13 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 357.0
CMS2_k127_3963187_14 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 321.0
CMS2_k127_3963187_15 ABC transporter transmembrane region K06148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 324.0
CMS2_k127_3963187_16 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 300.0
CMS2_k127_3963187_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002965 246.0
CMS2_k127_3963187_18 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000001509 220.0
CMS2_k127_3963187_19 Chemoreceptor zinc-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000002318 214.0
CMS2_k127_3963187_2 Endoribonuclease that initiates mRNA decay K18682 - - 1.271e-211 667.0
CMS2_k127_3963187_20 Bacterial transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000727 213.0
CMS2_k127_3963187_21 Cytochrome c family protein - - - 0.0000000000000000000000000000000000000000000000000000005875 198.0
CMS2_k127_3963187_22 thioesterase K02614 - - 0.00000000000000000000000000000000000005538 147.0
CMS2_k127_3963187_23 cytochrome c class I - - - 0.00000000000000000000000000000000001644 141.0
CMS2_k127_3963187_24 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000005242 126.0
CMS2_k127_3963187_25 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000001255 112.0
CMS2_k127_3963187_3 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 597.0
CMS2_k127_3963187_4 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 536.0
CMS2_k127_3963187_5 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 482.0
CMS2_k127_3963187_6 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 471.0
CMS2_k127_3963187_7 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 464.0
CMS2_k127_3963187_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 443.0
CMS2_k127_3963187_9 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 414.0
CMS2_k127_4106271_0 Sulfate permease family - - - 5.611e-229 719.0
CMS2_k127_4106271_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 504.0
CMS2_k127_4106271_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 314.0
CMS2_k127_4106271_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003387 261.0
CMS2_k127_4106271_4 PFAM Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000005603 258.0
CMS2_k127_4106271_5 Arylsulfatase - - - 0.0002926 46.0
CMS2_k127_4132860_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1470.0
CMS2_k127_4132860_1 DNA helicase K03657 - 3.6.4.12 0.0 1047.0
CMS2_k127_4132860_2 COG0659 Sulfate permease and related K03321 - - 9.951e-213 672.0
CMS2_k127_4132860_3 Type II secretion system K02455,K12278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 468.0
CMS2_k127_4165022_0 MgtC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 585.0
CMS2_k127_4165022_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 543.0
CMS2_k127_4165022_10 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000003495 87.0
CMS2_k127_4165022_11 Sodium/hydrogen exchanger family - - - 0.00000000000034 73.0
CMS2_k127_4165022_2 acid membrane antigen A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 399.0
CMS2_k127_4165022_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 390.0
CMS2_k127_4165022_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 388.0
CMS2_k127_4165022_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 363.0
CMS2_k127_4165022_6 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 332.0
CMS2_k127_4165022_7 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000001651 228.0
CMS2_k127_4165022_8 Belongs to the mannose-6-phosphate isomerase type 2 family K00971 - 2.7.7.13 0.000000000000000000000000000000003047 129.0
CMS2_k127_4165022_9 - - - - 0.000000000000000000006529 95.0
CMS2_k127_4167209_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.576e-317 980.0
CMS2_k127_4167209_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 1.983e-205 645.0
CMS2_k127_4167209_10 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000000000000000000000000000000000001378 147.0
CMS2_k127_4167209_11 - - - - 0.000000000000000000000000000000465 128.0
CMS2_k127_4167209_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 452.0
CMS2_k127_4167209_3 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 412.0
CMS2_k127_4167209_4 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 340.0
CMS2_k127_4167209_5 phage repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 318.0
CMS2_k127_4167209_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 316.0
CMS2_k127_4167209_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 296.0
CMS2_k127_4167209_8 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003213 272.0
CMS2_k127_4167209_9 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000004041 198.0
CMS2_k127_4252755_0 abc transporter atp-binding protein - - - 1.157e-295 913.0
CMS2_k127_4252755_1 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 9.311e-221 705.0
CMS2_k127_4252755_10 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 340.0
CMS2_k127_4252755_11 abc transporter atp-binding protein K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 330.0
CMS2_k127_4252755_12 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 319.0
CMS2_k127_4252755_13 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 309.0
CMS2_k127_4252755_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 301.0
CMS2_k127_4252755_15 protein conserved in bacteria K09859 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001838 289.0
CMS2_k127_4252755_16 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001044 273.0
CMS2_k127_4252755_17 PAS domain K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001339 263.0
CMS2_k127_4252755_18 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003427 252.0
CMS2_k127_4252755_19 protein conserved in bacteria K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000532 239.0
CMS2_k127_4252755_2 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 584.0
CMS2_k127_4252755_20 SMART GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003023 240.0
CMS2_k127_4252755_21 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000001495 196.0
CMS2_k127_4252755_22 - - - - 0.0000000000000000000000000000000000000000000164 167.0
CMS2_k127_4252755_23 SEC-C motif K09858 - - 0.000000000000000000000000000000000000000003076 159.0
CMS2_k127_4252755_24 YjbR - - - 0.000000000000000000000000000000000000000005834 156.0
CMS2_k127_4252755_25 - - - - 0.00000000000000000000000000000000000002038 148.0
CMS2_k127_4252755_27 S4 domain K14761 - - 0.0000000000000000000000003394 107.0
CMS2_k127_4252755_28 Protein of unknown function (DUF1653) - - - 0.0000000000000000000001466 98.0
CMS2_k127_4252755_29 Lipoprotein - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000002747 84.0
CMS2_k127_4252755_3 DUF1704 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 577.0
CMS2_k127_4252755_30 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000004192 84.0
CMS2_k127_4252755_31 Translation initiation factor SUI1 K03113 - - 0.00000000001861 68.0
CMS2_k127_4252755_32 Protein of unknown function (DUF2892) - - - 0.00000000002421 65.0
CMS2_k127_4252755_33 - - - - 0.000000003145 63.0
CMS2_k127_4252755_4 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 532.0
CMS2_k127_4252755_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 468.0
CMS2_k127_4252755_6 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 466.0
CMS2_k127_4252755_7 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 425.0
CMS2_k127_4252755_8 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 421.0
CMS2_k127_4252755_9 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 396.0
CMS2_k127_4282990_0 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains K02584 - - 2.405e-266 829.0
CMS2_k127_4282990_1 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 5.116e-229 723.0
CMS2_k127_4282990_10 TIGRFAM SagB-type dehydrogenase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004412 286.0
CMS2_k127_4282990_11 Low-potential electron donor to a number of redox enzymes K03839 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 271.0
CMS2_k127_4282990_12 Nitrogen fixation protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005528 228.0
CMS2_k127_4282990_13 Dinitrogenase iron-molybdenum cofactor biosynthesis protein K02596 - - 0.000000000000000000000000000000000000000000000000000000000000000635 223.0
CMS2_k127_4282990_14 Nitrogen fixation protein NifW K02595 - - 0.000000000000000000000000000000000000000000000000000000000003171 209.0
CMS2_k127_4282990_15 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000001243 190.0
CMS2_k127_4282990_16 - - - - 0.0000000000000000000000000000000000000000000000006109 182.0
CMS2_k127_4282990_17 Ferredoxin - - - 0.000000000000000000000000000000000000000000000001165 178.0
CMS2_k127_4282990_18 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000001903 159.0
CMS2_k127_4282990_19 Belongs to the ArsC family - - - 0.0000000000000000000000000000000001769 140.0
CMS2_k127_4282990_2 Belongs to the NifD NifK NifE NifN family K02592 - - 4.354e-222 694.0
CMS2_k127_4282990_20 NifQ K15790 - - 0.0000000000000000000000000000000004425 134.0
CMS2_k127_4282990_21 Ferredoxin - - - 0.00000000000000000000000000001788 119.0
CMS2_k127_4282990_22 - - - - 0.000000000000000000000111 100.0
CMS2_k127_4282990_23 nitrogen fixation protein FixT K02593 - - 0.0000000000000000000001121 98.0
CMS2_k127_4282990_24 NifZ domain K02597 - - 0.00000000000000000002871 95.0
CMS2_k127_4282990_26 - - - - 0.000000000448 69.0
CMS2_k127_4282990_3 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 2.49e-220 689.0
CMS2_k127_4282990_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 8.117e-212 665.0
CMS2_k127_4282990_5 COG0714 MoxR-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 543.0
CMS2_k127_4282990_6 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 517.0
CMS2_k127_4282990_7 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 472.0
CMS2_k127_4282990_8 Putative metallopeptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 428.0
CMS2_k127_4282990_9 AhpC/TSA family K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001126 277.0
CMS2_k127_4332268_0 Peptidase s1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 477.0
CMS2_k127_4332268_1 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 471.0
CMS2_k127_4332268_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 410.0
CMS2_k127_4332268_3 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 355.0
CMS2_k127_4332268_4 LssY C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 345.0
CMS2_k127_4332268_5 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000008442 178.0
CMS2_k127_4332268_6 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000000000000000002056 181.0
CMS2_k127_4332268_7 Membrane K08984 - - 0.0000000000000000000000000000000000000476 149.0
CMS2_k127_4332268_8 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000000003639 139.0
CMS2_k127_4338079_0 Mitochondrial degradasome RNA helicase subunit C terminal K17675 - 3.6.4.13 1.567e-320 1007.0
CMS2_k127_4338079_1 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 601.0
CMS2_k127_4338079_10 Protein of unknown function, DUF481 K07283 - - 0.000000000000000000000000000001074 133.0
CMS2_k127_4338079_11 Domain of unknown function (DUF309) - - - 0.000000000000000000000000000007449 123.0
CMS2_k127_4338079_12 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000001558 122.0
CMS2_k127_4338079_14 - - - - 0.00000004211 54.0
CMS2_k127_4338079_15 - - - - 0.00000005289 55.0
CMS2_k127_4338079_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 480.0
CMS2_k127_4338079_3 Major facilitator superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 430.0
CMS2_k127_4338079_4 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 307.0
CMS2_k127_4338079_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000005118 256.0
CMS2_k127_4338079_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003895 253.0
CMS2_k127_4338079_7 - - - - 0.00000000000000000000000000000000000000000000000001608 197.0
CMS2_k127_4338079_8 RDD family - - - 0.0000000000000000000000000000000000000000000001859 174.0
CMS2_k127_4338079_9 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000000000001215 162.0
CMS2_k127_4588938_0 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 295.0
CMS2_k127_4588938_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000002308 242.0
CMS2_k127_4588938_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000004928 234.0
CMS2_k127_4588938_3 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000007659 203.0
CMS2_k127_4588938_4 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000002719 153.0
CMS2_k127_4588938_5 Sensors of blue-light using FAD - - - 0.00000000000000000000000000000000001074 151.0
CMS2_k127_4588938_6 Cupin domain - - - 0.0000003026 51.0
CMS2_k127_4777905_0 Oligosaccharide transferase K07151 - 2.4.99.18 7.719e-227 722.0
CMS2_k127_4777905_1 Polysaccharide biosynthesis protein K15912 - 4.2.1.135 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 570.0
CMS2_k127_4777905_2 glycosyl transferase K13007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006313 287.0
CMS2_k127_4777905_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000003515 195.0
CMS2_k127_4777905_4 Capsule polysaccharide biosynthesis protein - - - 0.000000000000000000000000000007175 134.0
CMS2_k127_4777905_5 PFAM glycosyl transferase group 1 - - - 0.00000000009555 73.0
CMS2_k127_4777905_6 Glycosyl transferase family 2 K07011 - - 0.0000003954 53.0
CMS2_k127_5029789_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 2.719e-198 629.0
CMS2_k127_5029789_1 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 471.0
CMS2_k127_5029789_10 COGs COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000001774 203.0
CMS2_k127_5029789_11 homoserine kinase type II (Protein kinase fold) K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000005698 191.0
CMS2_k127_5029789_12 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000009997 185.0
CMS2_k127_5029789_13 RNA-binding protein homologous to eukaryotic snRNP - - - 0.0000000000000000000000000007976 116.0
CMS2_k127_5029789_14 - - - - 0.000000007425 61.0
CMS2_k127_5029789_2 phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 370.0
CMS2_k127_5029789_3 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 332.0
CMS2_k127_5029789_4 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 315.0
CMS2_k127_5029789_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 311.0
CMS2_k127_5029789_6 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000009331 270.0
CMS2_k127_5029789_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000008623 221.0
CMS2_k127_5029789_8 PFAM Cobinamide kinase cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000000003378 201.0
CMS2_k127_5029789_9 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000012 203.0
CMS2_k127_505592_0 COGs COG1033 exporter of the RND superfamily protein K07003 - - 1.058e-306 957.0
CMS2_k127_505592_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 444.0
CMS2_k127_505592_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 365.0
CMS2_k127_505592_3 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 352.0
CMS2_k127_505592_4 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000001165 237.0
CMS2_k127_505592_5 WHG domain - - - 0.0000000000000000000000000000000000000000000000000000006901 199.0
CMS2_k127_505592_6 ABC-type multidrug transport system, permease component K01992 - - 0.000000000001562 70.0
CMS2_k127_5097104_0 Amidase K01457 - 3.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 599.0
CMS2_k127_5097104_1 Allophanate hydrolase subunit 1 K01941 - 6.3.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 575.0
CMS2_k127_5097104_10 CMP dCMP deaminase K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000000000001993 238.0
CMS2_k127_5097104_11 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004044 232.0
CMS2_k127_5097104_12 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000001405 212.0
CMS2_k127_5097104_13 amidase activity K01457 - 3.5.1.54 0.000000000000000000000000000000000000000000000000000000000003574 210.0
CMS2_k127_5097104_14 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000005531 203.0
CMS2_k127_5097104_15 - - - - 0.0000000000000000000000000000000000000000000000003669 181.0
CMS2_k127_5097104_16 Dinitrogenase iron-molybdenum cofactor biosynthesis protein K02596 - - 0.0000000000000000000000000000000000002261 144.0
CMS2_k127_5097104_17 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000004809 132.0
CMS2_k127_5097104_19 molybdate ion transport K02017,K06857 - 3.6.3.29,3.6.3.55 0.0000000000000000000001286 103.0
CMS2_k127_5097104_2 Cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 485.0
CMS2_k127_5097104_20 lipoprotein - - - 0.000000000000000001022 90.0
CMS2_k127_5097104_3 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 458.0
CMS2_k127_5097104_4 Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 379.0
CMS2_k127_5097104_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 319.0
CMS2_k127_5097104_6 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 302.0
CMS2_k127_5097104_7 COGs COG2454 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001213 256.0
CMS2_k127_5097104_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004608 251.0
CMS2_k127_5097104_9 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001157 252.0
CMS2_k127_5097327_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1062.0
CMS2_k127_5097327_1 Sulfite dehydrogenase (Cytochrome) subunit SorA apoprotein K07147 - - 2.683e-202 638.0
CMS2_k127_5097327_10 Domain of unknown function (DUF4430) - - - 0.000000000000000000000000009298 113.0
CMS2_k127_5097327_11 - - - - 0.000000000000000000000004912 104.0
CMS2_k127_5097327_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 442.0
CMS2_k127_5097327_3 Transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 352.0
CMS2_k127_5097327_4 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 287.0
CMS2_k127_5097327_5 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003896 262.0
CMS2_k127_5097327_6 - - - - 0.0000000000000000000000000000000000000000000000000000000006734 205.0
CMS2_k127_5097327_7 cytochrome C oxidoreductase subunit B - - - 0.000000000000000000000000000000000000000000004484 164.0
CMS2_k127_5097327_9 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000000000005531 112.0
CMS2_k127_5104164_0 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 1.078e-315 969.0
CMS2_k127_5104164_1 Nitrogenase protein alpha chain K02586 - 1.18.6.1 1.559e-301 927.0
CMS2_k127_5104164_10 Glycosyltransferase like family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 514.0
CMS2_k127_5104164_11 COG4886 Leucine-rich repeat (LRR) protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 488.0
CMS2_k127_5104164_12 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 467.0
CMS2_k127_5104164_13 alanine dehydrogenase K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 456.0
CMS2_k127_5104164_14 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 422.0
CMS2_k127_5104164_15 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 399.0
CMS2_k127_5104164_16 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 365.0
CMS2_k127_5104164_17 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 332.0
CMS2_k127_5104164_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000001402 221.0
CMS2_k127_5104164_19 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000001525 184.0
CMS2_k127_5104164_2 Nitrogenase cofactor biosynthesis protein NifB K02585 - - 6.157e-280 863.0
CMS2_k127_5104164_20 PFAM Ferric reductase domain protein transmembrane component domain K17247 - - 0.00000000000000000000000000000000000000000000005656 175.0
CMS2_k127_5104164_21 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000003573 161.0
CMS2_k127_5104164_22 - - - - 0.000000000000000000000000000000000000005288 149.0
CMS2_k127_5104164_24 Pathogenicity locus - - - 0.0000000000000000000000000000004045 124.0
CMS2_k127_5104164_25 - - - - 0.0000000000000000000000000000006773 123.0
CMS2_k127_5104164_27 Rop-like - - - 0.0000000000000000001234 91.0
CMS2_k127_5104164_28 homolog of gamma-carboxymuconolactone decarboxylase subunit - - - 0.00000000000000002122 86.0
CMS2_k127_5104164_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.532e-222 694.0
CMS2_k127_5104164_30 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000005588 74.0
CMS2_k127_5104164_4 Cysteine desulfurase K04487 - 2.8.1.7 6.822e-219 682.0
CMS2_k127_5104164_5 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 574.0
CMS2_k127_5104164_6 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 599.0
CMS2_k127_5104164_7 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 549.0
CMS2_k127_5104164_8 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 542.0
CMS2_k127_5104164_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 545.0
CMS2_k127_5108213_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.105e-267 831.0
CMS2_k127_5108213_1 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 548.0
CMS2_k127_5108213_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 397.0
CMS2_k127_5108213_3 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002021 246.0
CMS2_k127_5108213_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000195 78.0
CMS2_k127_5123364_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 8.053e-259 805.0
CMS2_k127_5123364_1 Belongs to the GARS family K01945 - 6.3.4.13 1.017e-230 720.0
CMS2_k127_5123364_2 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 9.098e-215 691.0
CMS2_k127_5123364_3 COG1055 Na H antiporter NhaD and related arsenite - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 540.0
CMS2_k127_5123364_4 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 389.0
CMS2_k127_5123364_5 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001091 245.0
CMS2_k127_5123364_6 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000001862 179.0
CMS2_k127_5123364_7 RDD family - - - 0.000000000000000000000000000000000000000002313 160.0
CMS2_k127_5169907_0 ATP-dependent CLP protease ATP-binding subunit K03694 - - 2.975e-273 858.0
CMS2_k127_5169907_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.866e-215 672.0
CMS2_k127_5169907_10 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 519.0
CMS2_k127_5169907_11 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 494.0
CMS2_k127_5169907_12 Butirosin biosynthesis protein H, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 488.0
CMS2_k127_5169907_13 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 469.0
CMS2_k127_5169907_14 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 449.0
CMS2_k127_5169907_15 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 437.0
CMS2_k127_5169907_16 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 441.0
CMS2_k127_5169907_17 permease K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 434.0
CMS2_k127_5169907_18 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 430.0
CMS2_k127_5169907_19 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 422.0
CMS2_k127_5169907_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.103e-210 659.0
CMS2_k127_5169907_20 Belongs to the beta-ketoacyl-ACP synthases family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 417.0
CMS2_k127_5169907_21 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 376.0
CMS2_k127_5169907_22 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 371.0
CMS2_k127_5169907_23 component I K01665 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 359.0
CMS2_k127_5169907_24 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 331.0
CMS2_k127_5169907_25 HAD-superfamily hydrolase, subfamily IIA K02566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 318.0
CMS2_k127_5169907_26 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 328.0
CMS2_k127_5169907_27 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007709 311.0
CMS2_k127_5169907_28 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 306.0
CMS2_k127_5169907_29 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 291.0
CMS2_k127_5169907_3 Aromatic amino acid lyase K01745 - 4.3.1.3 3.056e-199 632.0
CMS2_k127_5169907_30 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000007978 252.0
CMS2_k127_5169907_31 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000001054 255.0
CMS2_k127_5169907_32 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000003496 246.0
CMS2_k127_5169907_33 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000001457 236.0
CMS2_k127_5169907_34 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000004882 227.0
CMS2_k127_5169907_35 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000006255 209.0
CMS2_k127_5169907_36 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000698 207.0
CMS2_k127_5169907_37 beta-ketoacyl-acyl-carrier-protein synthase II activity - - - 0.00000000000000000000000000000000000000000000000000001733 201.0
CMS2_k127_5169907_38 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000001688 184.0
CMS2_k127_5169907_39 - - - - 0.000000000000000000000000000000000000000000000007006 176.0
CMS2_k127_5169907_4 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal - - - 4.103e-196 616.0
CMS2_k127_5169907_40 (HIT) family - - - 0.0000000000000000000000000000000000000000000004729 169.0
CMS2_k127_5169907_41 beta-lactamase - - - 0.000000000000000000000000000000000000002115 162.0
CMS2_k127_5169907_42 Lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000008012 153.0
CMS2_k127_5169907_43 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000001659 142.0
CMS2_k127_5169907_44 metal-binding, possibly nucleic acid-binding protein - - - 0.000000000000000000000000000001884 123.0
CMS2_k127_5169907_45 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000001235 123.0
CMS2_k127_5169907_46 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000001654 119.0
CMS2_k127_5169907_47 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000004619 104.0
CMS2_k127_5169907_48 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042171,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.51 0.0000000000000000000002372 107.0
CMS2_k127_5169907_49 Phosphopantetheine attachment site K02078 - - 0.000000000000000001922 89.0
CMS2_k127_5169907_5 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 600.0
CMS2_k127_5169907_50 - - - - 0.0000000000000005264 84.0
CMS2_k127_5169907_51 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000004912 77.0
CMS2_k127_5169907_52 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000001378 80.0
CMS2_k127_5169907_53 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.00000000000005045 77.0
CMS2_k127_5169907_54 META domain - - - 0.0000000000008824 78.0
CMS2_k127_5169907_55 Phosphopantetheine attachment site K02078 - - 0.0000000005207 63.0
CMS2_k127_5169907_56 - - - - 0.0000005271 61.0
CMS2_k127_5169907_57 - - - - 0.00006764 51.0
CMS2_k127_5169907_6 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 566.0
CMS2_k127_5169907_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 539.0
CMS2_k127_5169907_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 530.0
CMS2_k127_5169907_9 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 528.0
CMS2_k127_5182324_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 1.069e-299 942.0
CMS2_k127_5182324_1 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 489.0
CMS2_k127_5182324_2 Belongs to the RimK family K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 485.0
CMS2_k127_5182324_3 CorA-like Mg2 transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 331.0
CMS2_k127_5182324_4 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 314.0
CMS2_k127_5182324_5 Putative ATP-dependant zinc protease - - - 0.000000000000000000000000000000000000000000025 165.0
CMS2_k127_5192183_0 - K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 603.0
CMS2_k127_5192183_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 554.0
CMS2_k127_5192183_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 498.0
CMS2_k127_5192183_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 292.0
CMS2_k127_5192183_4 PhoU family K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 285.0
CMS2_k127_5192183_5 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000002003 202.0
CMS2_k127_5192183_6 FR47-like protein - - - 0.0001843 46.0
CMS2_k127_5194405_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1295.0
CMS2_k127_5194405_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 0.0 1174.0
CMS2_k127_5194405_10 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 575.0
CMS2_k127_5194405_11 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 535.0
CMS2_k127_5194405_12 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 522.0
CMS2_k127_5194405_13 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 454.0
CMS2_k127_5194405_14 lytic murein transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 459.0
CMS2_k127_5194405_15 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 447.0
CMS2_k127_5194405_16 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 423.0
CMS2_k127_5194405_17 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 422.0
CMS2_k127_5194405_18 lytic murein transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 421.0
CMS2_k127_5194405_19 hmm pf00534 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 408.0
CMS2_k127_5194405_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1039.0
CMS2_k127_5194405_20 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 390.0
CMS2_k127_5194405_21 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 395.0
CMS2_k127_5194405_22 hydrolase, TatD K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 385.0
CMS2_k127_5194405_23 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 358.0
CMS2_k127_5194405_24 Metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 348.0
CMS2_k127_5194405_25 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 344.0
CMS2_k127_5194405_26 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 324.0
CMS2_k127_5194405_27 Imidazoleglycerol-phosphate dehydratase K01089,K01693 - 3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 300.0
CMS2_k127_5194405_28 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 300.0
CMS2_k127_5194405_29 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 302.0
CMS2_k127_5194405_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1032.0
CMS2_k127_5194405_30 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 290.0
CMS2_k127_5194405_31 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002405 285.0
CMS2_k127_5194405_32 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005743 278.0
CMS2_k127_5194405_33 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001641 271.0
CMS2_k127_5194405_34 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006529 264.0
CMS2_k127_5194405_35 acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000001251 229.0
CMS2_k127_5194405_36 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001628 218.0
CMS2_k127_5194405_37 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000000001177 213.0
CMS2_k127_5194405_38 G T U mismatch-specific DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000003901 200.0
CMS2_k127_5194405_39 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000001806 198.0
CMS2_k127_5194405_4 PFAM Acyl-CoA dehydrogenase, C-terminal domain K06445 - - 1.801e-251 798.0
CMS2_k127_5194405_40 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000001241 186.0
CMS2_k127_5194405_41 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000003179 179.0
CMS2_k127_5194405_42 Lipopolysaccharide transport periplasmic protein lpta K09774 - - 0.0000000000000000000000000000000000000000000424 165.0
CMS2_k127_5194405_43 hmm pf01863 K07043 - - 0.000000000000000000000000000000000001005 147.0
CMS2_k127_5194405_44 YGGT family K02221 - - 0.00000000000000000000000000000000005248 136.0
CMS2_k127_5194405_46 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000001492 129.0
CMS2_k127_5194405_47 Protein of unknown function (DUF504) - - - 0.0000000000000000000000001384 108.0
CMS2_k127_5194405_49 Chlorite dismutase - - - 0.000000000000000000000004121 107.0
CMS2_k127_5194405_5 penicillin-binding protein K05515 - 3.4.16.4 5.767e-248 778.0
CMS2_k127_5194405_50 - - - - 0.000000000000000000575 89.0
CMS2_k127_5194405_51 - - - - 0.00000000000000004905 82.0
CMS2_k127_5194405_53 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000006007 51.0
CMS2_k127_5194405_6 Oxidoreductase K06151 - 1.1.99.3 1.028e-243 764.0
CMS2_k127_5194405_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.917e-216 677.0
CMS2_k127_5194405_8 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.019e-207 651.0
CMS2_k127_5194405_9 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 617.0
CMS2_k127_5214971_0 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 557.0
CMS2_k127_5214971_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 474.0
CMS2_k127_5214971_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 408.0
CMS2_k127_5214971_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 353.0
CMS2_k127_5239679_0 ATP citrate synthase K15230 - 2.3.3.8 0.0 1124.0
CMS2_k127_5239679_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1096.0
CMS2_k127_5239679_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 9.981e-300 928.0
CMS2_k127_5239679_3 Belongs to the succinate malate CoA ligase beta subunit family K15231 - 2.3.3.8 6.355e-249 772.0
CMS2_k127_5239679_4 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 3.394e-197 617.0
CMS2_k127_5239679_5 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 346.0
CMS2_k127_5239679_6 Anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 322.0
CMS2_k127_5239679_7 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000002862 196.0
CMS2_k127_5239679_8 general secretion pathway protein - - - 0.0000000000000000000000000000114 125.0
CMS2_k127_5327679_0 ABC transporter K11085 - - 2.558e-248 777.0
CMS2_k127_5327679_1 Bacterial sugar transferase K00996 - 2.7.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 391.0
CMS2_k127_5327679_2 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 376.0
CMS2_k127_5371319_0 UPF0313 protein - - - 2.043e-287 885.0
CMS2_k127_5371319_1 arsenite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 581.0
CMS2_k127_5371319_2 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 364.0
CMS2_k127_5371319_3 Subtilisin-like serine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 353.0
CMS2_k127_5371319_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 310.0
CMS2_k127_5371319_5 TraB family K09973 - - 0.0000000000000000000000000000000000000000000000009788 186.0
CMS2_k127_5371319_6 - - - - 0.00000000000000000000000000000000000001344 152.0
CMS2_k127_5375772_0 DNA helicase K03657 - 3.6.4.12 0.0 1053.0
CMS2_k127_5375772_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 1.023e-310 964.0
CMS2_k127_5375772_2 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 2.95e-281 869.0
CMS2_k127_5375772_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 6.577e-247 769.0
CMS2_k127_5375772_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 386.0
CMS2_k127_5375772_5 COG0433 Predicted ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 336.0
CMS2_k127_5375772_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 330.0
CMS2_k127_5375772_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000008699 139.0
CMS2_k127_5414638_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1077.0
CMS2_k127_5414638_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 6.506e-246 767.0
CMS2_k127_5414638_10 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 385.0
CMS2_k127_5414638_11 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 364.0
CMS2_k127_5414638_12 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 305.0
CMS2_k127_5414638_13 dna polymerase iii K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 302.0
CMS2_k127_5414638_14 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001988 258.0
CMS2_k127_5414638_15 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000002165 254.0
CMS2_k127_5414638_17 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000001639 138.0
CMS2_k127_5414638_18 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000001243 115.0
CMS2_k127_5414638_19 Outer membrane protein beta-barrel domain - - - 0.000000000000000000009217 99.0
CMS2_k127_5414638_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 3.523e-225 701.0
CMS2_k127_5414638_20 helix_turn_helix, Lux Regulon - - - 0.00000000008097 65.0
CMS2_k127_5414638_3 Potassium channel protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 569.0
CMS2_k127_5414638_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 516.0
CMS2_k127_5414638_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 517.0
CMS2_k127_5414638_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 520.0
CMS2_k127_5414638_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 494.0
CMS2_k127_5414638_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 488.0
CMS2_k127_5414638_9 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 417.0
CMS2_k127_5438436_0 Heat shock 70 kDa protein K04043 - - 3.332e-267 834.0
CMS2_k127_5438436_1 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 2.873e-215 677.0
CMS2_k127_5438436_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 401.0
CMS2_k127_5438436_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 286.0
CMS2_k127_5438436_4 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000000008542 174.0
CMS2_k127_5438436_5 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000002402 155.0
CMS2_k127_5438436_6 COG1734 DnaK suppressor protein K06204 - - 0.00000000000000000000000000000009554 127.0
CMS2_k127_5438436_7 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000003419 85.0
CMS2_k127_5591177_0 Allophanate hydrolase subunit 1 K01941 - 6.3.4.6 0.0 1311.0
CMS2_k127_5591177_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 331.0
CMS2_k127_5591177_2 Amidase K01457 - 3.5.1.54 0.0000000000000000000000000000000000000000000000000000000000001698 222.0
CMS2_k127_5737983_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 1.882e-195 616.0
CMS2_k127_5737983_1 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 462.0
CMS2_k127_5737983_2 HPP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001446 254.0
CMS2_k127_5737983_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000002046 226.0
CMS2_k127_5737983_4 Belongs to the globin family K05916 - 1.14.12.17 0.00000000000000000000000000000000000000000000000000002575 191.0
CMS2_k127_5737983_5 competence protein K02237 - - 0.0000000000000006474 81.0
CMS2_k127_5737983_6 Polysaccharide biosynthesis protein - - - 0.00002419 46.0
CMS2_k127_5737983_7 Belongs to the ompA family K03286 - - 0.0001549 52.0
CMS2_k127_5745029_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1377.0
CMS2_k127_5745029_1 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 5.242e-237 739.0
CMS2_k127_5745029_10 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
CMS2_k127_5745029_11 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000009085 223.0
CMS2_k127_5745029_12 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000016 201.0
CMS2_k127_5745029_13 Biopolymer transporter ExbB K03561 - - 0.0000000000000000000000000000000000000000000000000000008365 195.0
CMS2_k127_5745029_14 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000002979 171.0
CMS2_k127_5745029_15 biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000000003916 161.0
CMS2_k127_5745029_16 START domain - - - 0.0000000000000000000000000686 118.0
CMS2_k127_5745029_17 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000003095 97.0
CMS2_k127_5745029_2 Ammonium Transporter K03320 - - 5.455e-227 708.0
CMS2_k127_5745029_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 9.848e-210 655.0
CMS2_k127_5745029_4 Ammonium Transporter K03320 - - 8.167e-208 650.0
CMS2_k127_5745029_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 548.0
CMS2_k127_5745029_6 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 532.0
CMS2_k127_5745029_7 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 404.0
CMS2_k127_5745029_8 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 372.0
CMS2_k127_5745029_9 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 298.0
CMS2_k127_5754316_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 2.897e-250 782.0
CMS2_k127_5754316_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 444.0
CMS2_k127_5754316_2 PFAM Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 408.0
CMS2_k127_5754316_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005665 263.0
CMS2_k127_5754316_4 metal cluster binding - - - 0.000000000000000000000000000000003868 133.0
CMS2_k127_5754316_5 belongs to the thioredoxin family K03671 - - 0.00000000000000000000001799 103.0
CMS2_k127_5973934_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1138.0
CMS2_k127_5973934_1 RNA binding S1 domain protein K06959 - - 0.0 1049.0
CMS2_k127_5973934_10 Evidence 4 Homologs of previously reported genes of K09700 - - 0.0000000000000000000000000000000000000000000000005394 176.0
CMS2_k127_5973934_12 metal-dependent phosphohydrolase HD sub domain - - - 0.00000000006922 68.0
CMS2_k127_5973934_2 pyrroloquinoline quinone binding - - - 3.628e-239 751.0
CMS2_k127_5973934_3 DUF1704 - - - 2.859e-194 614.0
CMS2_k127_5973934_4 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 612.0
CMS2_k127_5973934_5 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 511.0
CMS2_k127_5973934_6 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 475.0
CMS2_k127_5973934_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 363.0
CMS2_k127_5973934_8 Mate efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 362.0
CMS2_k127_5973934_9 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000000000000000000000000005796 203.0
CMS2_k127_603721_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 520.0
CMS2_k127_603721_1 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 395.0
CMS2_k127_603721_2 mannosylglycerate metabolic process K05947,K07026,K15918 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,2.7.1.31,3.1.3.70 0.00000000000000000000000000000000000000000000000000000004091 220.0
CMS2_k127_603721_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000005659 176.0
CMS2_k127_603721_4 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000000002827 164.0
CMS2_k127_603721_5 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000001335 103.0
CMS2_k127_603721_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000003934 51.0
CMS2_k127_6112462_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 5.136e-210 655.0
CMS2_k127_6112462_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 430.0
CMS2_k127_6112462_10 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000007375 215.0
CMS2_k127_6112462_11 chain release factor K15034 - - 0.000000000000000000000000000000000000000000000000000000000006124 209.0
CMS2_k127_6112462_12 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000001482 202.0
CMS2_k127_6112462_13 secretion protein HlyD K01993 - - 0.000000000000000000000000002578 115.0
CMS2_k127_6112462_14 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000004151 94.0
CMS2_k127_6112462_16 alanine dehydrogenase K00259 - 1.4.1.1 0.00001884 48.0
CMS2_k127_6112462_2 Metal cation transporter, ZIP family K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 398.0
CMS2_k127_6112462_3 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 344.0
CMS2_k127_6112462_4 alpha beta K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 317.0
CMS2_k127_6112462_5 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 312.0
CMS2_k127_6112462_6 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 289.0
CMS2_k127_6112462_7 PhnA Zinc-Ribbon K06193 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001648 275.0
CMS2_k127_6112462_8 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000008799 232.0
CMS2_k127_6112462_9 Copper resistance protein B precursor (CopB) K07233 - - 0.00000000000000000000000000000000000000000000000000000000000001422 218.0
CMS2_k127_6132426_0 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 608.0
CMS2_k127_6132426_1 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 431.0
CMS2_k127_6132426_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000001439 231.0
CMS2_k127_6132426_11 phosphoribosyltransferase K00769 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000002928 220.0
CMS2_k127_6132426_12 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000000000000005018 214.0
CMS2_k127_6132426_13 Peptide-methionine (R)-S-oxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000003902 196.0
CMS2_k127_6132426_14 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000003728 171.0
CMS2_k127_6132426_15 amidase activity K03796 - - 0.00000000000000000000000000000000000006086 155.0
CMS2_k127_6132426_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 431.0
CMS2_k127_6132426_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 364.0
CMS2_k127_6132426_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 370.0
CMS2_k127_6132426_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 357.0
CMS2_k127_6132426_6 PFAM amine oxidase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 335.0
CMS2_k127_6132426_7 lipid a biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 315.0
CMS2_k127_6132426_8 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 284.0
CMS2_k127_6132426_9 Prolyl 4-hydroxylase alpha subunit homologues. K07394 - - 0.0000000000000000000000000000000000000000000000000000000000000000009871 235.0
CMS2_k127_6167930_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1769.0
CMS2_k127_6167930_1 Belongs to the ClpA ClpB family K03694,K03695 - - 0.0 1373.0
CMS2_k127_6167930_10 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 3.006e-209 653.0
CMS2_k127_6167930_11 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.041e-203 643.0
CMS2_k127_6167930_12 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 1.861e-199 638.0
CMS2_k127_6167930_13 fructose-bisphosphate aldolase K01624 - 4.1.2.13 3.239e-196 615.0
CMS2_k127_6167930_14 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 602.0
CMS2_k127_6167930_15 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 590.0
CMS2_k127_6167930_16 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 559.0
CMS2_k127_6167930_17 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 536.0
CMS2_k127_6167930_18 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 508.0
CMS2_k127_6167930_19 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 509.0
CMS2_k127_6167930_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1052.0
CMS2_k127_6167930_20 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 499.0
CMS2_k127_6167930_21 dihydropteroate synthase K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 483.0
CMS2_k127_6167930_22 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 490.0
CMS2_k127_6167930_23 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 479.0
CMS2_k127_6167930_24 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 467.0
CMS2_k127_6167930_25 4Fe-4S ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 437.0
CMS2_k127_6167930_26 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 432.0
CMS2_k127_6167930_27 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 437.0
CMS2_k127_6167930_28 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 411.0
CMS2_k127_6167930_29 PFAM 5'-nucleotidase K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 406.0
CMS2_k127_6167930_3 Heat shock 70 kDa protein K04043 - - 0.0 1013.0
CMS2_k127_6167930_30 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 383.0
CMS2_k127_6167930_31 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 379.0
CMS2_k127_6167930_32 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 374.0
CMS2_k127_6167930_33 riboflavin biosynthesis protein K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 377.0
CMS2_k127_6167930_34 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 365.0
CMS2_k127_6167930_35 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 350.0
CMS2_k127_6167930_36 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 351.0
CMS2_k127_6167930_37 COG1252 NADH dehydrogenase FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 352.0
CMS2_k127_6167930_38 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 338.0
CMS2_k127_6167930_39 Dipeptidase K01270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 343.0
CMS2_k127_6167930_4 Fatty acid cis/trans isomerase (CTI) - - - 1.105e-287 903.0
CMS2_k127_6167930_40 Jag_N K06346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 334.0
CMS2_k127_6167930_41 peptidylprolyl isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 324.0
CMS2_k127_6167930_42 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 320.0
CMS2_k127_6167930_43 1-aminocyclopropane-1-carboxylate deaminase K01505 - 3.5.99.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 306.0
CMS2_k127_6167930_44 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000001048 265.0
CMS2_k127_6167930_45 ABC transporter, ATP-binding protein K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002451 265.0
CMS2_k127_6167930_46 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000001625 266.0
CMS2_k127_6167930_47 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000003138 260.0
CMS2_k127_6167930_48 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009936 262.0
CMS2_k127_6167930_49 DNA processing protein K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001866 253.0
CMS2_k127_6167930_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 5.044e-239 743.0
CMS2_k127_6167930_50 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002814 253.0
CMS2_k127_6167930_51 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001878 241.0
CMS2_k127_6167930_52 DNA replication regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000004965 238.0
CMS2_k127_6167930_53 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000003772 235.0
CMS2_k127_6167930_54 Formylmethanofuran dehydrogenase, subunit e - - - 0.00000000000000000000000000000000000000000000000000000000000000002248 230.0
CMS2_k127_6167930_55 PFAM Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000005869 231.0
CMS2_k127_6167930_56 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000002933 223.0
CMS2_k127_6167930_57 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000005826 227.0
CMS2_k127_6167930_58 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000001244 222.0
CMS2_k127_6167930_59 transformation system protein K02242 - - 0.000000000000000000000000000000000000000000000000000000000000002113 222.0
CMS2_k127_6167930_6 COG0642 Signal transduction histidine kinase - - - 3.507e-224 712.0
CMS2_k127_6167930_60 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000005845 199.0
CMS2_k127_6167930_61 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000007956 195.0
CMS2_k127_6167930_62 - - - - 0.00000000000000000000000000000000000000000000000000003246 195.0
CMS2_k127_6167930_63 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000004706 189.0
CMS2_k127_6167930_64 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000002106 188.0
CMS2_k127_6167930_65 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000456 190.0
CMS2_k127_6167930_66 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000005776 189.0
CMS2_k127_6167930_67 Membrane - - - 0.000000000000000000000000000000000000000000000000007922 188.0
CMS2_k127_6167930_68 Highly conserved protein containing a thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000002218 183.0
CMS2_k127_6167930_69 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000002205 179.0
CMS2_k127_6167930_7 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 5.243e-213 673.0
CMS2_k127_6167930_70 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000002737 177.0
CMS2_k127_6167930_71 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000000000000000000000000000147 163.0
CMS2_k127_6167930_72 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000008414 162.0
CMS2_k127_6167930_73 protein conserved in bacteria K09928 - - 0.000000000000000000000000000000000000003811 152.0
CMS2_k127_6167930_74 Could be involved in insertion of integral membrane proteins into the membrane - - - 0.000000000000000000000000000000000000004576 147.0
CMS2_k127_6167930_75 - - - - 0.0000000000000000000000000000000000000873 145.0
CMS2_k127_6167930_76 Protein required for attachment to host cells - - - 0.000000000000000000000000000000000001925 143.0
CMS2_k127_6167930_77 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000001832 136.0
CMS2_k127_6167930_78 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000002903 133.0
CMS2_k127_6167930_8 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.027e-212 665.0
CMS2_k127_6167930_80 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000002584 123.0
CMS2_k127_6167930_81 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000009128 119.0
CMS2_k127_6167930_82 - - - - 0.000000000000000000001352 98.0
CMS2_k127_6167930_83 Cupin domain K11312 - - 0.00000000000000000000149 100.0
CMS2_k127_6167930_84 OmpA-like transmembrane domain - - - 0.000000000000000007756 91.0
CMS2_k127_6167930_85 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000006715 80.0
CMS2_k127_6167930_9 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 3.897e-210 659.0
CMS2_k127_6224891_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1244.0
CMS2_k127_6224891_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 3.732e-311 954.0
CMS2_k127_6224891_10 COG3893 inactivated superfamily I helicase - - - 2.411e-216 698.0
CMS2_k127_6224891_11 Belongs to the CarA family K01956 - 6.3.5.5 4.903e-201 631.0
CMS2_k127_6224891_12 transporter - - - 7.243e-198 625.0
CMS2_k127_6224891_13 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 2.289e-197 622.0
CMS2_k127_6224891_14 pyruvate ferredoxin oxidoreductase K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 601.0
CMS2_k127_6224891_15 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 588.0
CMS2_k127_6224891_16 molybdopterin biosynthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 520.0
CMS2_k127_6224891_17 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 417.0
CMS2_k127_6224891_18 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 392.0
CMS2_k127_6224891_19 PFAM tRNA synthetase class II (G H P and S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 388.0
CMS2_k127_6224891_2 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 2.159e-269 857.0
CMS2_k127_6224891_20 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 361.0
CMS2_k127_6224891_21 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 359.0
CMS2_k127_6224891_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 362.0
CMS2_k127_6224891_23 modulator of drug activity K03923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 334.0
CMS2_k127_6224891_24 pyruvate ferredoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 329.0
CMS2_k127_6224891_25 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 303.0
CMS2_k127_6224891_26 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 291.0
CMS2_k127_6224891_27 Hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 287.0
CMS2_k127_6224891_28 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002809 282.0
CMS2_k127_6224891_29 protein conserved in bacteria K09804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001559 271.0
CMS2_k127_6224891_3 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 5.814e-248 776.0
CMS2_k127_6224891_30 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000821 269.0
CMS2_k127_6224891_31 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000006887 252.0
CMS2_k127_6224891_32 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007906 244.0
CMS2_k127_6224891_33 pyruvate ferredoxin oxidoreductase K00171 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000005325 241.0
CMS2_k127_6224891_34 molybdopterin converting factor K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000001452 235.0
CMS2_k127_6224891_35 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000008651 228.0
CMS2_k127_6224891_36 PFAM Methyltransferase type - - - 0.0000000000000000000000000000000000000000000000000000000000000001336 228.0
CMS2_k127_6224891_37 Protein of unknown function, DUF481 - - - 0.0000000000000000000000000000000000000000000000000000000000000002818 234.0
CMS2_k127_6224891_38 - - - - 0.000000000000000000000000000000000000000000000000000000000001449 226.0
CMS2_k127_6224891_39 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000001896 220.0
CMS2_k127_6224891_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.444e-242 754.0
CMS2_k127_6224891_40 carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000001534 212.0
CMS2_k127_6224891_41 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000787 200.0
CMS2_k127_6224891_42 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000001088 190.0
CMS2_k127_6224891_43 FixH - - - 0.00000000000000000000000000000000000000000000000002303 185.0
CMS2_k127_6224891_44 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000005916 166.0
CMS2_k127_6224891_45 COG1393 Arsenate reductase and related K00537 - 1.20.4.1 0.000000000000000000000000000000000000002446 154.0
CMS2_k127_6224891_46 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000000000000000000037 134.0
CMS2_k127_6224891_47 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000009527 123.0
CMS2_k127_6224891_48 molybdopterin converting factor K03636 - - 0.000000000000000000000000000001518 121.0
CMS2_k127_6224891_49 Domain of unknown function (DUF3817) - - - 0.00000000000000000000005105 104.0
CMS2_k127_6224891_5 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 5.529e-238 741.0
CMS2_k127_6224891_50 Family of unknown function (DUF4006) - - - 0.00000000000000000001185 93.0
CMS2_k127_6224891_51 Rubredoxin - - - 0.00000000000000000001387 91.0
CMS2_k127_6224891_52 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.00000000000000000001603 94.0
CMS2_k127_6224891_53 PFAM Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000001418 89.0
CMS2_k127_6224891_54 Outer membrane porin - - - 0.000000000005427 78.0
CMS2_k127_6224891_55 Sulfatase-modifying factor enzyme 1 K11912 - 2.7.11.1 0.00001163 54.0
CMS2_k127_6224891_6 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 5.996e-224 698.0
CMS2_k127_6224891_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.466e-221 692.0
CMS2_k127_6224891_8 Abc transporter K02035 - - 7.795e-217 683.0
CMS2_k127_6224891_9 FGGY family of carbohydrate kinases, N-terminal domain K11216 - 2.7.1.189 2.335e-216 682.0
CMS2_k127_6242846_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1097.0
CMS2_k127_6242846_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1073.0
CMS2_k127_6242846_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 439.0
CMS2_k127_6242846_11 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 383.0
CMS2_k127_6242846_12 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 305.0
CMS2_k127_6242846_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
CMS2_k127_6242846_15 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000008278 262.0
CMS2_k127_6242846_16 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000001022 203.0
CMS2_k127_6242846_17 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000001858 201.0
CMS2_k127_6242846_18 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000004424 210.0
CMS2_k127_6242846_19 Macro domain - - - 0.000000000000000000000000000000000000000000000000000002289 196.0
CMS2_k127_6242846_2 PFAM biotin lipoyl attachment domain-containing protein K01960 - 6.4.1.1 8.029e-300 927.0
CMS2_k127_6242846_20 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000002951 166.0
CMS2_k127_6242846_21 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000008021 151.0
CMS2_k127_6242846_22 - - - - 0.0000000000000000000000000000000002217 134.0
CMS2_k127_6242846_23 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000386 130.0
CMS2_k127_6242846_24 PFAM peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000001933 122.0
CMS2_k127_6242846_25 Histidine kinase K03407 - 2.7.13.3 0.00000000000000000000002946 110.0
CMS2_k127_6242846_26 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000608 91.0
CMS2_k127_6242846_27 thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000000002164 89.0
CMS2_k127_6242846_28 Oxaloacetate decarboxylase, gamma chain K01573 - 4.1.1.3 0.00000000000000004049 83.0
CMS2_k127_6242846_29 - - - - 0.00000000000000004548 84.0
CMS2_k127_6242846_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 3.711e-229 715.0
CMS2_k127_6242846_30 Belongs to the universal stress protein A family - - - 0.0000000001438 72.0
CMS2_k127_6242846_31 beta-lactamase activity K07126 - - 0.000003624 59.0
CMS2_k127_6242846_32 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.0008134 46.0
CMS2_k127_6242846_4 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 3.469e-227 719.0
CMS2_k127_6242846_5 molybdopterin oxidoreductase - - - 4.844e-226 716.0
CMS2_k127_6242846_6 COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit K01572 - 4.1.1.3 3.387e-224 701.0
CMS2_k127_6242846_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 587.0
CMS2_k127_6242846_8 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 578.0
CMS2_k127_6242846_9 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 520.0
CMS2_k127_6255396_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1030.0
CMS2_k127_6255396_1 transporter antisigma-factor antagonist STAS K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 496.0
CMS2_k127_6255396_10 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000003528 198.0
CMS2_k127_6255396_11 Acyl carrier protein phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000002785 185.0
CMS2_k127_6255396_12 helicase activity - - - 0.0000000000000000000000000000000000000000000887 173.0
CMS2_k127_6255396_13 Cold-shock protein K03704 - - 0.0000000000000000000000000000000000002578 141.0
CMS2_k127_6255396_15 ankyrin repeat K21440 - - 0.00000000000000000000000000000000007871 143.0
CMS2_k127_6255396_16 - - - - 0.0000000000000000000000000000000007939 132.0
CMS2_k127_6255396_17 Transglycosylase associated protein - - - 0.000000000000000000000000000003703 122.0
CMS2_k127_6255396_19 - - - - 0.0000000000000000000000000003233 116.0
CMS2_k127_6255396_2 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 344.0
CMS2_k127_6255396_20 Protein of unknown function (DUF3185) - - - 0.00000000000000000000000003491 108.0
CMS2_k127_6255396_21 Domain of unknown function (DUF389) - - - 0.00000000000000000000001025 102.0
CMS2_k127_6255396_22 - - - - 0.000000000000000001549 88.0
CMS2_k127_6255396_23 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000007439 73.0
CMS2_k127_6255396_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 326.0
CMS2_k127_6255396_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 324.0
CMS2_k127_6255396_5 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 289.0
CMS2_k127_6255396_6 SMART zinc finger, CDGSH-type domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002709 274.0
CMS2_k127_6255396_7 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009667 231.0
CMS2_k127_6255396_8 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001956 228.0
CMS2_k127_6255396_9 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000003042 223.0
CMS2_k127_6344473_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1083.0
CMS2_k127_6344473_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.568e-320 987.0
CMS2_k127_6344473_10 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 398.0
CMS2_k127_6344473_11 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 410.0
CMS2_k127_6344473_12 response regulator K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 362.0
CMS2_k127_6344473_13 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 323.0
CMS2_k127_6344473_14 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 309.0
CMS2_k127_6344473_15 involved in molybdopterin and thiamine biosynthesis family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 303.0
CMS2_k127_6344473_16 PFAM dUTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 296.0
CMS2_k127_6344473_17 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000995 282.0
CMS2_k127_6344473_18 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008904 257.0
CMS2_k127_6344473_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000002463 237.0
CMS2_k127_6344473_2 Sulfatase-modifying factor enzyme 1 - - - 9.157e-283 885.0
CMS2_k127_6344473_20 PFAM NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001803 239.0
CMS2_k127_6344473_21 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000002482 196.0
CMS2_k127_6344473_22 cofactor binding K09979 - - 0.00000000000000000000000000000000000000000005637 164.0
CMS2_k127_6344473_23 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000004158 143.0
CMS2_k127_6344473_24 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000002468 152.0
CMS2_k127_6344473_26 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000001736 124.0
CMS2_k127_6344473_27 GDSL-like lipase acylhydrolase - - - 0.000000000000000000000000003513 117.0
CMS2_k127_6344473_28 NADPH-dependent FMN reductase K00355 - 1.6.5.2 0.0000000000000000000000000189 116.0
CMS2_k127_6344473_29 iron ion homeostasis K04758 - - 0.00000000000000000004554 92.0
CMS2_k127_6344473_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 7.955e-276 856.0
CMS2_k127_6344473_30 - - - - 0.0000000000000001257 88.0
CMS2_k127_6344473_31 Membrane - - - 0.00000000002262 70.0
CMS2_k127_6344473_32 - - - - 0.0000000004153 63.0
CMS2_k127_6344473_33 - - - - 0.0000000006675 66.0
CMS2_k127_6344473_34 - - - - 0.0002651 49.0
CMS2_k127_6344473_4 Belongs to the DEAD box helicase family K05592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 7.056e-237 741.0
CMS2_k127_6344473_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 526.0
CMS2_k127_6344473_6 Cache domain K02480,K03406 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 492.0
CMS2_k127_6344473_7 Aminotransferase, class I K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 476.0
CMS2_k127_6344473_8 DNA recombination protein K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 476.0
CMS2_k127_6344473_9 Histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 437.0
CMS2_k127_6544407_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 582.0
CMS2_k127_6544407_1 COG0155 Sulfite reductase, beta subunit (hemoprotein) K00366,K00392 - 1.7.7.1,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009101 550.0
CMS2_k127_6544407_10 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.0000000000000000000000000000000002063 135.0
CMS2_k127_6544407_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 337.0
CMS2_k127_6544407_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 320.0
CMS2_k127_6544407_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 313.0
CMS2_k127_6544407_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000001682 214.0
CMS2_k127_6544407_6 COGs COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000001024 202.0
CMS2_k127_6544407_7 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000007348 187.0
CMS2_k127_6544407_8 homoserine kinase type II (Protein kinase fold) K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000009682 187.0
CMS2_k127_6544407_9 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000003541 159.0
CMS2_k127_6544520_0 Allophanate hydrolase subunit 1 K01941 - 6.3.4.6 0.0 1840.0
CMS2_k127_6544520_1 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 431.0
CMS2_k127_6544520_2 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 431.0
CMS2_k127_6544520_3 Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 366.0
CMS2_k127_6544520_4 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 334.0
CMS2_k127_6544520_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 323.0
CMS2_k127_6544520_6 Amidase K01457 - 3.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000006586 222.0
CMS2_k127_6563950_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.678e-226 707.0
CMS2_k127_6563950_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.12e-219 689.0
CMS2_k127_6563950_10 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 351.0
CMS2_k127_6563950_11 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 342.0
CMS2_k127_6563950_12 Belongs to the pseudouridine synthase RluA family K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 345.0
CMS2_k127_6563950_13 COG1579 Zn-ribbon protein possibly nucleic acid-binding K07164,K22391 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 329.0
CMS2_k127_6563950_14 dinuclear metal center protein, YbgI K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 314.0
CMS2_k127_6563950_15 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001146 283.0
CMS2_k127_6563950_16 protein conserved in bacteria K09778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005612 259.0
CMS2_k127_6563950_17 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000005847 233.0
CMS2_k127_6563950_18 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000000000005432 220.0
CMS2_k127_6563950_19 - K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000001287 210.0
CMS2_k127_6563950_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 4.294e-216 677.0
CMS2_k127_6563950_20 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000002544 208.0
CMS2_k127_6563950_21 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000001415 200.0
CMS2_k127_6563950_22 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP - - - 0.00000000000000000000000000000000000000000000000001007 207.0
CMS2_k127_6563950_23 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000000006399 151.0
CMS2_k127_6563950_24 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000006176 152.0
CMS2_k127_6563950_25 Putative transmembrane protein (PGPGW) - - - 0.0000000000000000000000000000000000008323 145.0
CMS2_k127_6563950_26 Histidine kinase K07648,K07679 - 2.7.13.3 0.0000000000000000000000000000000001882 147.0
CMS2_k127_6563950_27 - - - - 0.000000000000000000000000000000005943 139.0
CMS2_k127_6563950_28 - - - - 0.0000000000000000000000000000000103 128.0
CMS2_k127_6563950_29 - - - - 0.000000000000000000000000002829 113.0
CMS2_k127_6563950_3 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 509.0
CMS2_k127_6563950_31 PFAM Fimbrial assembly family protein - - - 0.00000000000000001078 89.0
CMS2_k127_6563950_32 - - - - 0.00000000000001066 83.0
CMS2_k127_6563950_33 - - - - 0.00000000000008417 78.0
CMS2_k127_6563950_34 Belongs to the UPF0109 family K06960 - - 0.0000005188 54.0
CMS2_k127_6563950_4 3-deoxy-d-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 479.0
CMS2_k127_6563950_5 ABC transporter permease K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 456.0
CMS2_k127_6563950_6 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 427.0
CMS2_k127_6563950_7 4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 420.0
CMS2_k127_6563950_8 Belongs to the 'phage' integrase family K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 358.0
CMS2_k127_6563950_9 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 355.0
CMS2_k127_6631621_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1307.0
CMS2_k127_6631621_1 phosphate transporter K03306 - - 1.356e-215 682.0
CMS2_k127_6631621_10 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 322.0
CMS2_k127_6631621_11 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000008377 259.0
CMS2_k127_6631621_12 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001546 251.0
CMS2_k127_6631621_13 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000007694 134.0
CMS2_k127_6631621_14 MOSC domain - - - 0.00000000000000000000000642 108.0
CMS2_k127_6631621_15 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000001382 100.0
CMS2_k127_6631621_16 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00004342 47.0
CMS2_k127_6631621_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.323e-199 628.0
CMS2_k127_6631621_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 586.0
CMS2_k127_6631621_4 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 554.0
CMS2_k127_6631621_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 498.0
CMS2_k127_6631621_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 463.0
CMS2_k127_6631621_7 phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 451.0
CMS2_k127_6631621_8 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 449.0
CMS2_k127_6631621_9 (EAL) domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 371.0
CMS2_k127_6657045_0 Amidohydrolase family - - - 2.023e-211 670.0
CMS2_k127_6657045_1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 359.0
CMS2_k127_6657045_2 hmm pf01841 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 291.0
CMS2_k127_6657045_3 Trypsin-like serine protease - - - 0.0000000000000000000004338 109.0
CMS2_k127_6657045_4 Heavy-metal-associated domain K08364 - - 0.00000000000000003757 87.0
CMS2_k127_6657045_6 integral membrane protein - - - 0.0001627 51.0
CMS2_k127_6657045_7 Belongs to the sulfur carrier protein TusA family K08363 - - 0.0002876 48.0
CMS2_k127_6735635_0 Multicopper oxidase K22348 - 1.16.3.3 5.327e-247 774.0
CMS2_k127_6735635_1 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000001367 243.0
CMS2_k127_6735635_2 DNA polymerase Ligase (LigD) - - - 0.0000000000000000000000000000000000000000000000004106 180.0
CMS2_k127_6735635_3 Copper resistance protein B precursor (CopB) K07233 - - 0.000000000000000000006657 99.0
CMS2_k127_6735635_4 Pas domain - - - 0.0004335 46.0
CMS2_k127_676383_0 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K03581 - 3.1.11.5 0.0 1028.0
CMS2_k127_676383_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 562.0
CMS2_k127_676383_10 PKD domain - - - 0.0000000000000000000006712 111.0
CMS2_k127_676383_11 Immune inhibitor A peptidase M6 - - - 0.0000004367 57.0
CMS2_k127_676383_2 Cytochrome K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 490.0
CMS2_k127_676383_3 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000948 270.0
CMS2_k127_676383_4 COGs COG3786 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000978 226.0
CMS2_k127_676383_5 M6 family metalloprotease domain protein - - - 0.00000000000000000000000000000000000000000000000001736 199.0
CMS2_k127_676383_6 Na H antiporter - - - 0.0000000000000000000000000000000000000003337 153.0
CMS2_k127_676383_7 Belongs to the Fur family K09825 - - 0.000000000000000000000000000000000000002813 150.0
CMS2_k127_676383_8 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000001713 123.0
CMS2_k127_676383_9 epimerase - - - 0.000000000000000000000000000002392 129.0
CMS2_k127_6886054_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 5.883e-236 740.0
CMS2_k127_6886054_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 4.601e-209 654.0
CMS2_k127_6886054_2 Arginosuccinate synthase K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 493.0
CMS2_k127_6886054_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001338 263.0
CMS2_k127_6886054_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000001114 188.0
CMS2_k127_6886054_5 Cytochrome c - - - 0.000000000000000000000000000000000000000008516 158.0
CMS2_k127_6886054_6 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000001354 124.0
CMS2_k127_6886054_7 Acyltransferase family - GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008374,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016020,GO:0016051,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046378,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576 - 0.0000000000000001149 87.0
CMS2_k127_6913687_0 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 6.237e-210 661.0
CMS2_k127_6913687_1 Mechanosensitive ion channel - - - 4.804e-194 622.0
CMS2_k127_6913687_2 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 509.0
CMS2_k127_6913687_3 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 484.0
CMS2_k127_6913687_4 polyphosphate kinase K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 434.0
CMS2_k127_6913687_5 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 391.0
CMS2_k127_6913687_6 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 389.0
CMS2_k127_6913687_7 Ester cyclase - - - 0.00000000000000000000000000000000000000003263 155.0
CMS2_k127_6949113_0 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1201.0
CMS2_k127_6949113_1 COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase K15022 - 1.17.1.10 0.0 1165.0
CMS2_k127_6949113_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 330.0
CMS2_k127_6949113_11 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006311 270.0
CMS2_k127_6949113_12 polyphosphate kinase K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000003203 198.0
CMS2_k127_6949113_13 putative NADH-ubiquinone oxidoreductase chain E K00334 - 1.6.5.3 0.0000000000000000000000000000000008783 130.0
CMS2_k127_6949113_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000006934 110.0
CMS2_k127_6949113_15 NADH dehydrogenase (ubiquinone) activity K00330 - 1.6.5.3 0.00000000000000304 80.0
CMS2_k127_6949113_2 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1040.0
CMS2_k127_6949113_3 ATPase (AAA - - - 9.205e-274 851.0
CMS2_k127_6949113_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.525e-255 789.0
CMS2_k127_6949113_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 7.128e-216 681.0
CMS2_k127_6949113_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 580.0
CMS2_k127_6949113_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 422.0
CMS2_k127_6949113_8 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 408.0
CMS2_k127_6949113_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 351.0
CMS2_k127_6981505_0 hydrogenase (NiFe) small subunit HydA K05927 - 1.12.5.1 0.0 1154.0
CMS2_k127_6981505_1 Methyltransferase type 11 K07755 - 2.1.1.137 1.406e-194 617.0
CMS2_k127_6981505_2 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 511.0
CMS2_k127_6981505_3 NADPH quinone reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007725 235.0
CMS2_k127_773301_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1212.0
CMS2_k127_773301_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.516e-251 779.0
CMS2_k127_773301_10 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 402.0
CMS2_k127_773301_11 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 393.0
CMS2_k127_773301_12 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 364.0
CMS2_k127_773301_13 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
CMS2_k127_773301_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004811 273.0
CMS2_k127_773301_15 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008154 270.0
CMS2_k127_773301_16 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001199 251.0
CMS2_k127_773301_17 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002158 234.0
CMS2_k127_773301_18 COG2346 Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000000000000000001639 192.0
CMS2_k127_773301_19 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000001354 184.0
CMS2_k127_773301_2 Belongs to the aldehyde dehydrogenase family - - - 1.258e-243 759.0
CMS2_k127_773301_20 Protein of unknown function (DUF523) - - - 0.000000000000000000000000000000000000000003035 163.0
CMS2_k127_773301_21 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000000001878 140.0
CMS2_k127_773301_22 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000001244 121.0
CMS2_k127_773301_23 ABC-2 type transporter K09688 - - 0.00000000000000000000344 101.0
CMS2_k127_773301_24 Protein conserved in bacteria - - - 0.0000000000000000003504 98.0
CMS2_k127_773301_3 Aminotransferase K14261 - - 1.384e-231 720.0
CMS2_k127_773301_4 homoserine dehydrogenase K00003 - 1.1.1.3 9.309e-208 653.0
CMS2_k127_773301_5 Radical SAM protein K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 543.0
CMS2_k127_773301_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 533.0
CMS2_k127_773301_7 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 516.0
CMS2_k127_773301_8 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 509.0
CMS2_k127_773301_9 molybdopterin biosynthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 428.0
CMS2_k127_942364_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1066.0
CMS2_k127_942364_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.263e-290 899.0
CMS2_k127_942364_2 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 386.0
CMS2_k127_942364_3 Na H antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 375.0
CMS2_k127_942364_4 membrane-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007234 271.0
CMS2_k127_942364_5 Psort location Cytoplasmic, score 9.97 - - - 0.0000000000000000000000000000000000000004997 158.0
CMS2_k127_942364_6 - - - - 0.0000000000000000000000000000597 121.0
CMS2_k127_942364_7 Cytochrome c553 K08738 - - 0.000000000000000000000001384 105.0
CMS2_k127_942364_8 - - - - 0.00000000000000001593 83.0
CMS2_k127_942364_9 transformation system protein K02456 - - 0.00000000000000009095 84.0
CMS2_k127_961457_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 0.0 1182.0
CMS2_k127_961457_1 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 579.0
CMS2_k127_961457_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 488.0
CMS2_k127_961457_3 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 444.0
CMS2_k127_961457_4 Hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 413.0
CMS2_k127_961457_5 Long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 342.0
CMS2_k127_961457_6 Archaea bacterial proteins of unknown function K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 334.0
CMS2_k127_961457_7 polyphosphate kinase K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000001464 236.0
CMS2_k127_961457_8 - - - - 0.00000000000000000000000000000000000001474 149.0
CMS2_k127_961457_9 deoxyribonuclease I activity K01150 - 3.1.21.1 0.0000000000000000000000000000000008572 140.0