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Overview

ID MAG00464
Name CMS2_bin.8
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus G020354665
Species G020354665 sp020354665
Assembly information
Completeness (%) 100.0
Contamination (%) 1.48
GC content (%) 68.0
N50 (bp) 43,867
Genome size (bp) 3,811,356

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3500

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1023398_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1938.0
CMS2_k127_1023398_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1371.0
CMS2_k127_1023398_10 ABC transporter - - - 1.182e-239 754.0
CMS2_k127_1023398_11 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.35e-230 728.0
CMS2_k127_1023398_12 Extracellular liganD-binding receptor K01999 - - 1.365e-214 680.0
CMS2_k127_1023398_13 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 1.923e-208 651.0
CMS2_k127_1023398_14 3-isopropylmalate dehydratase large subunit K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 602.0
CMS2_k127_1023398_15 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 545.0
CMS2_k127_1023398_16 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 554.0
CMS2_k127_1023398_17 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 530.0
CMS2_k127_1023398_18 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 527.0
CMS2_k127_1023398_19 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 510.0
CMS2_k127_1023398_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1150.0
CMS2_k127_1023398_20 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 498.0
CMS2_k127_1023398_21 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 487.0
CMS2_k127_1023398_22 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 480.0
CMS2_k127_1023398_23 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 451.0
CMS2_k127_1023398_24 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 436.0
CMS2_k127_1023398_25 Isocitrate lyase and phosphorylmutase K01841 - 5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 425.0
CMS2_k127_1023398_26 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 410.0
CMS2_k127_1023398_27 PFAM secretion protein HlyD family protein K01993,K16922 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 397.0
CMS2_k127_1023398_28 PFAM ABC transporter related K01995,K10822 - 3.6.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 381.0
CMS2_k127_1023398_29 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 351.0
CMS2_k127_1023398_3 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1097.0
CMS2_k127_1023398_30 UbiC transcription regulator-associated K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 323.0
CMS2_k127_1023398_31 protein domain associated with - - - 0.000000000000000000000000000000000000000000000000000000000000000009056 229.0
CMS2_k127_1023398_32 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000178 223.0
CMS2_k127_1023398_33 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002617 233.0
CMS2_k127_1023398_34 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000000000000005487 224.0
CMS2_k127_1023398_35 Belongs to the LeuD family K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000002859 221.0
CMS2_k127_1023398_36 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000000000001019 212.0
CMS2_k127_1023398_37 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000577 226.0
CMS2_k127_1023398_38 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000000000000000000000000000000000000000000000000000003405 203.0
CMS2_k127_1023398_39 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000000000000000004037 184.0
CMS2_k127_1023398_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1079.0
CMS2_k127_1023398_40 Ribosome-associated heat shock protein K04762 - - 0.000000000000000000000000000000000000000000002392 168.0
CMS2_k127_1023398_41 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000009277 166.0
CMS2_k127_1023398_42 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000001604 170.0
CMS2_k127_1023398_43 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000000000000000002779 151.0
CMS2_k127_1023398_44 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000001392 147.0
CMS2_k127_1023398_45 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000002113 141.0
CMS2_k127_1023398_46 Histone family protein nucleoid-structuring protein H-NS K03746 - - 0.00000000000000000000000000000002257 129.0
CMS2_k127_1023398_47 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.0000000000000000000000000004259 116.0
CMS2_k127_1023398_48 - - - - 0.0000000000000004998 82.0
CMS2_k127_1023398_49 - - - - 0.00000000000006424 77.0
CMS2_k127_1023398_5 PFAM amidohydrolase K01464,K01466 - 3.5.2.2,3.5.2.5 5.729e-278 865.0
CMS2_k127_1023398_6 GGDEF domain - - - 3.336e-272 870.0
CMS2_k127_1023398_7 Tripartite tricarboxylate transporter TctA family K07793 - - 9.15e-258 802.0
CMS2_k127_1023398_8 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 1.63e-250 787.0
CMS2_k127_1023398_9 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 8.513e-243 761.0
CMS2_k127_1121056_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1463.0
CMS2_k127_1121056_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1145.0
CMS2_k127_1121056_10 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008509 319.0
CMS2_k127_1121056_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 319.0
CMS2_k127_1121056_12 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000005092 272.0
CMS2_k127_1121056_13 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007551 247.0
CMS2_k127_1121056_14 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000006652 241.0
CMS2_k127_1121056_15 peptidylprolyl isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000004994 241.0
CMS2_k127_1121056_16 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.000000000000000000000000000000000000000000000000000000000000000000004326 237.0
CMS2_k127_1121056_17 - - - - 0.000000000000000000000000000000000000000000000000001356 186.0
CMS2_k127_1121056_18 adenylate kinase activity K00939,K01939 - 2.7.4.3,6.3.4.4 0.00000000000000000000000000000000000000000000000002504 194.0
CMS2_k127_1121056_19 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.00000000000000000000000000000000000000000000000003901 187.0
CMS2_k127_1121056_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 4.632e-219 685.0
CMS2_k127_1121056_20 - - - - 0.0000000000000000000000000000000000000000000000728 181.0
CMS2_k127_1121056_21 - - - - 0.000000000000000000000000000000000000000002063 163.0
CMS2_k127_1121056_22 - - - - 0.0000000000000000000000000003749 123.0
CMS2_k127_1121056_23 - - - - 0.000000000000000000000000005049 115.0
CMS2_k127_1121056_24 PFAM carboxyl transferase K01615 - 4.1.1.70 0.00000000000000002596 81.0
CMS2_k127_1121056_25 - - - - 0.000006298 53.0
CMS2_k127_1121056_3 Major Facilitator Superfamily - - - 3.18e-203 639.0
CMS2_k127_1121056_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 583.0
CMS2_k127_1121056_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 499.0
CMS2_k127_1121056_6 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 466.0
CMS2_k127_1121056_7 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 457.0
CMS2_k127_1121056_8 NlpB/DapX lipoprotein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 438.0
CMS2_k127_1121056_9 Thioredoxin-like K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 326.0
CMS2_k127_1142530_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1712.0
CMS2_k127_1142530_1 cytochrome C K02198 - - 2.783e-281 874.0
CMS2_k127_1142530_10 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000000000000009327 172.0
CMS2_k127_1142530_11 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000000005641 170.0
CMS2_k127_1142530_12 Metal-sensitive transcriptional repressor - - - 0.000000000000000000000000000000002946 131.0
CMS2_k127_1142530_13 Protein of unknown function (DUF2892) - - - 0.00000000000000000000001477 101.0
CMS2_k127_1142530_14 PFAM Di-haem cytochrome c - - - 0.00000000000000000001478 99.0
CMS2_k127_1142530_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 551.0
CMS2_k127_1142530_3 Histidine kinase K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 533.0
CMS2_k127_1142530_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 381.0
CMS2_k127_1142530_5 PFAM response regulator receiver K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 337.0
CMS2_k127_1142530_6 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 331.0
CMS2_k127_1142530_7 Cytochrome B561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 295.0
CMS2_k127_1142530_8 Periplasmic protein thiol K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003333 267.0
CMS2_k127_1142530_9 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000003389 207.0
CMS2_k127_1171150_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1740.0
CMS2_k127_1171150_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1171.0
CMS2_k127_1171150_10 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 3.155e-196 621.0
CMS2_k127_1171150_11 AFG1-like ATPase K06916 - - 7.617e-195 614.0
CMS2_k127_1171150_12 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 619.0
CMS2_k127_1171150_13 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 600.0
CMS2_k127_1171150_14 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008862 581.0
CMS2_k127_1171150_15 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 572.0
CMS2_k127_1171150_16 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 568.0
CMS2_k127_1171150_17 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 557.0
CMS2_k127_1171150_18 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 545.0
CMS2_k127_1171150_19 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 526.0
CMS2_k127_1171150_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1099.0
CMS2_k127_1171150_20 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 520.0
CMS2_k127_1171150_21 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 522.0
CMS2_k127_1171150_22 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 494.0
CMS2_k127_1171150_23 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 502.0
CMS2_k127_1171150_24 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 478.0
CMS2_k127_1171150_25 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 488.0
CMS2_k127_1171150_26 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 474.0
CMS2_k127_1171150_27 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 481.0
CMS2_k127_1171150_28 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 449.0
CMS2_k127_1171150_29 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 437.0
CMS2_k127_1171150_3 PFAM acyl-CoA dehydrogenase domain protein K20035 - - 1.327e-311 965.0
CMS2_k127_1171150_30 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 427.0
CMS2_k127_1171150_31 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009869 424.0
CMS2_k127_1171150_32 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 412.0
CMS2_k127_1171150_33 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 411.0
CMS2_k127_1171150_34 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 393.0
CMS2_k127_1171150_35 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 387.0
CMS2_k127_1171150_36 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 359.0
CMS2_k127_1171150_37 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 354.0
CMS2_k127_1171150_38 PFAM Phosphoribosyltransferase K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 324.0
CMS2_k127_1171150_39 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 317.0
CMS2_k127_1171150_4 HELICc2 K03722 - 3.6.4.12 4.827e-257 808.0
CMS2_k127_1171150_40 rRNA methyltransferase K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 327.0
CMS2_k127_1171150_41 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 313.0
CMS2_k127_1171150_42 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 304.0
CMS2_k127_1171150_43 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 298.0
CMS2_k127_1171150_44 Type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008713 283.0
CMS2_k127_1171150_45 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000005739 246.0
CMS2_k127_1171150_46 Belongs to the skp family K06142 - - 0.00000000000000000000000000000000000000000000000000000000000000009139 226.0
CMS2_k127_1171150_47 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000000000000000000000000000000000000000002537 214.0
CMS2_k127_1171150_48 Putative Tad-like Flp pilus-assembly - - - 0.00000000000000000000000000000000000000000000000002599 194.0
CMS2_k127_1171150_49 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000000000001532 159.0
CMS2_k127_1171150_5 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 3.466e-255 794.0
CMS2_k127_1171150_50 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000002261 164.0
CMS2_k127_1171150_51 O-Antigen ligase - - - 0.000000000000000000000000000000000000000097 169.0
CMS2_k127_1171150_52 PspC domain - - - 0.000000000000000000000000000000000002473 141.0
CMS2_k127_1171150_53 PFAM TadE family protein - - - 0.00000000000000000000000002217 115.0
CMS2_k127_1171150_54 Protein of unknown function (DUF465) - - - 0.0000000000000000000000127 102.0
CMS2_k127_1171150_55 LytR cell envelope-related transcriptional attenuator - - - 0.00000000000000000000001564 116.0
CMS2_k127_1171150_56 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000000004671 82.0
CMS2_k127_1171150_59 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00004587 46.0
CMS2_k127_1171150_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.574e-243 758.0
CMS2_k127_1171150_7 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.628e-225 709.0
CMS2_k127_1171150_8 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.499e-223 708.0
CMS2_k127_1171150_9 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.246e-210 657.0
CMS2_k127_1196201_0 Bacterial extracellular solute-binding protein K02027 - - 5.033e-233 731.0
CMS2_k127_1196201_1 NAD binding K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 323.0
CMS2_k127_1196201_2 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.00000000000000000000000000000000000000000000000000000000000000000001329 242.0
CMS2_k127_1196201_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000002361 129.0
CMS2_k127_1196201_4 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000001709 117.0
CMS2_k127_1232244_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 3.617e-231 721.0
CMS2_k127_1232244_1 NADPH-dependent glutamate synthase beta - - - 7.101e-198 620.0
CMS2_k127_1232244_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 598.0
CMS2_k127_1232244_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 538.0
CMS2_k127_1232244_4 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 456.0
CMS2_k127_1232244_5 Bifunctional DNA primase/polymerase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000452 285.0
CMS2_k127_1232244_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K18357 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002083 282.0
CMS2_k127_1232244_7 Nicotinamidase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000741 237.0
CMS2_k127_1246551_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 1.021e-278 873.0
CMS2_k127_1246551_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 4.243e-247 779.0
CMS2_k127_1246551_10 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 380.0
CMS2_k127_1246551_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 357.0
CMS2_k127_1246551_12 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 353.0
CMS2_k127_1246551_13 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 306.0
CMS2_k127_1246551_14 MAPEG family - - - 0.00000000000000000000000000000000000000000000000000000000000000002955 226.0
CMS2_k127_1246551_15 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000000000000006262 209.0
CMS2_k127_1246551_16 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000002391 139.0
CMS2_k127_1246551_17 - - - - 0.0000000000000000000000000000000000406 137.0
CMS2_k127_1246551_19 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000001039 110.0
CMS2_k127_1246551_2 Serine aminopeptidase, S33 - - - 2.486e-214 675.0
CMS2_k127_1246551_20 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000005791 99.0
CMS2_k127_1246551_21 Evidence 2b Function of strongly homologous gene K07497 - - 0.0000000000000000000002008 99.0
CMS2_k127_1246551_22 Transglycosylase associated protein - - - 0.00000000000000000008195 91.0
CMS2_k127_1246551_23 Protein of unknown function (DUF3617) - - - 0.0000000000000001038 89.0
CMS2_k127_1246551_24 - - - - 0.00000000003291 63.0
CMS2_k127_1246551_25 Integrase core domain - - - 0.000000002705 58.0
CMS2_k127_1246551_26 - - - - 0.000002657 52.0
CMS2_k127_1246551_3 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 570.0
CMS2_k127_1246551_4 UPF0365 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 502.0
CMS2_k127_1246551_5 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 484.0
CMS2_k127_1246551_6 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 462.0
CMS2_k127_1246551_7 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 447.0
CMS2_k127_1246551_8 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 422.0
CMS2_k127_1246551_9 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 414.0
CMS2_k127_1313710_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.0 1058.0
CMS2_k127_1313710_1 COG1653 ABC-type sugar transport system, periplasmic component K17321 - - 0.0 1002.0
CMS2_k127_1313710_10 Binding-protein-dependent transport system inner membrane component K17323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 466.0
CMS2_k127_1313710_11 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 460.0
CMS2_k127_1313710_12 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 449.0
CMS2_k127_1313710_13 ABC transporter (Permease K17322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 442.0
CMS2_k127_1313710_14 Belongs to the ABC transporter superfamily K17324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 440.0
CMS2_k127_1313710_15 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 413.0
CMS2_k127_1313710_16 PFAM regulatory protein DeoR K02444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 399.0
CMS2_k127_1313710_17 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 400.0
CMS2_k127_1313710_18 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 384.0
CMS2_k127_1313710_19 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 365.0
CMS2_k127_1313710_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.21e-246 775.0
CMS2_k127_1313710_20 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 353.0
CMS2_k127_1313710_21 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 344.0
CMS2_k127_1313710_22 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 338.0
CMS2_k127_1313710_23 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005638 269.0
CMS2_k127_1313710_24 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000279 265.0
CMS2_k127_1313710_25 DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007994 253.0
CMS2_k127_1313710_26 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000004266 204.0
CMS2_k127_1313710_27 Uncharacterised protein family (UPF0149) K07039 - - 0.0000000000000000000000000000000000000000000000000002417 193.0
CMS2_k127_1313710_28 Fasciclin domain - - - 0.000000000000000000000000000000000006976 139.0
CMS2_k127_1313710_29 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000000002405 132.0
CMS2_k127_1313710_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 5.568e-244 761.0
CMS2_k127_1313710_30 small integral membrane protein - - - 0.00000000000000000000000000001721 121.0
CMS2_k127_1313710_31 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000001078 102.0
CMS2_k127_1313710_32 chlorophyll binding - - - 0.0000000000000000000001508 104.0
CMS2_k127_1313710_4 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 4.15e-224 703.0
CMS2_k127_1313710_5 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 7.52e-219 687.0
CMS2_k127_1313710_6 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 3.554e-217 687.0
CMS2_k127_1313710_7 Aminotransferase class I and II K00832 - 2.6.1.57 9.138e-195 613.0
CMS2_k127_1313710_8 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 590.0
CMS2_k127_1313710_9 Belongs to the ABC transporter superfamily K17325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 478.0
CMS2_k127_1327842_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1550.0
CMS2_k127_1327842_1 TonB dependent receptor K02014 - - 6.858e-252 797.0
CMS2_k127_1327842_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 476.0
CMS2_k127_1327842_11 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 447.0
CMS2_k127_1327842_12 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 393.0
CMS2_k127_1327842_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 368.0
CMS2_k127_1327842_14 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 345.0
CMS2_k127_1327842_15 Pfam ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 340.0
CMS2_k127_1327842_16 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 330.0
CMS2_k127_1327842_17 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 313.0
CMS2_k127_1327842_18 Methyltransferase type 11 K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 296.0
CMS2_k127_1327842_19 Bacterial transcriptional repressor C-terminal K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005084 273.0
CMS2_k127_1327842_2 Proton-conducting membrane transporter K05568 - - 1.972e-220 696.0
CMS2_k127_1327842_20 TIGRFAM phasin family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000646 231.0
CMS2_k127_1327842_21 Na H antiporter, MnhB K05566 - - 0.000000000000000000000000000000000000000000000000000000000000000007249 235.0
CMS2_k127_1327842_22 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000000007817 219.0
CMS2_k127_1327842_23 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000000001269 214.0
CMS2_k127_1327842_24 Na H antiporter, MnhB K05566 - - 0.00000000000000000000000000000000000000000000000000000003511 209.0
CMS2_k127_1327842_25 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000005437 196.0
CMS2_k127_1327842_26 COG1863 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.000000000000000000000000000000000000000000000008761 177.0
CMS2_k127_1327842_27 COG1006 Multisubunit Na H antiporter, MnhC subunit K05567 - - 0.000000000000000000000000000000000000000001019 169.0
CMS2_k127_1327842_28 monovalent cation:proton antiporter activity K05571 - - 0.0000000000000000000000000000000000001568 143.0
CMS2_k127_1327842_29 Multiple resistance and pH regulation protein F K05570 - - 0.0000000000000000000000000000005294 125.0
CMS2_k127_1327842_3 Proton-conducting membrane transporter - - - 4.488e-219 693.0
CMS2_k127_1327842_30 Protein of unknown function (DUF1439) - - - 0.00000000000000000000000000257 121.0
CMS2_k127_1327842_31 - - - - 0.0000000000000000001556 93.0
CMS2_k127_1327842_32 methyltransferase - - - 0.00000000000005382 78.0
CMS2_k127_1327842_33 Domain of unknown function (DUF1992) - - - 0.00000000003476 69.0
CMS2_k127_1327842_4 Proton-conducting membrane transporter - - - 2.523e-211 688.0
CMS2_k127_1327842_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 528.0
CMS2_k127_1327842_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 530.0
CMS2_k127_1327842_7 D-isomer specific 2-hydroxyacid dehydrogenase K00090 - 1.1.1.215,1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 503.0
CMS2_k127_1327842_8 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 484.0
CMS2_k127_1327842_9 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 488.0
CMS2_k127_1428561_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1165.0
CMS2_k127_1428561_1 Hemolysin-type calcium-binding - - - 0.0 1123.0
CMS2_k127_1428561_10 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 561.0
CMS2_k127_1428561_11 HlyD membrane-fusion protein of T1SS K02022,K11003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 552.0
CMS2_k127_1428561_12 (Fe-S) oxidoreductase K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 400.0
CMS2_k127_1428561_13 (ABC) transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 372.0
CMS2_k127_1428561_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 393.0
CMS2_k127_1428561_15 PFAM Conserved TM helix repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 329.0
CMS2_k127_1428561_16 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 308.0
CMS2_k127_1428561_17 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002794 248.0
CMS2_k127_1428561_18 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001961 244.0
CMS2_k127_1428561_19 Sodium Bile acid symporter family - - - 0.00000000000000000000000000000000000000000000000000003362 199.0
CMS2_k127_1428561_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1056.0
CMS2_k127_1428561_20 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000004066 201.0
CMS2_k127_1428561_21 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000002659 178.0
CMS2_k127_1428561_22 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000003892 170.0
CMS2_k127_1428561_23 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000000000001492 118.0
CMS2_k127_1428561_24 - - - - 0.00000000000000000000000009121 110.0
CMS2_k127_1428561_25 - - - - 0.000000000000003802 76.0
CMS2_k127_1428561_27 Pfam Lipase (class 3) - - - 0.00000000396 72.0
CMS2_k127_1428561_3 Peptidase C39 family K11004 - - 0.0 1017.0
CMS2_k127_1428561_4 SMART alpha amylase, catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 3.711e-318 986.0
CMS2_k127_1428561_5 SMART alpha amylase catalytic sub domain K00705,K06044 - 2.4.1.25,5.4.99.15 3.069e-298 954.0
CMS2_k127_1428561_6 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 8.644e-248 792.0
CMS2_k127_1428561_7 trehalohydrolase K01236 - 3.2.1.141 6.22e-225 713.0
CMS2_k127_1428561_8 LUD domain K18929 - - 5.946e-219 690.0
CMS2_k127_1428561_9 Alkaline and neutral invertase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 613.0
CMS2_k127_1474000_0 Lytic transglycosylase catalytic K08309 - - 4.017e-242 766.0
CMS2_k127_1474000_1 TrkA-C domain K03499 - - 2.33e-237 741.0
CMS2_k127_1474000_10 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 317.0
CMS2_k127_1474000_11 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 310.0
CMS2_k127_1474000_12 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002169 264.0
CMS2_k127_1474000_13 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000000000000005771 140.0
CMS2_k127_1474000_14 - - - - 0.00000001822 63.0
CMS2_k127_1474000_15 - - - - 0.00006785 48.0
CMS2_k127_1474000_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 1.026e-207 657.0
CMS2_k127_1474000_3 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 600.0
CMS2_k127_1474000_4 Domain of unknown function (DUF3482) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 545.0
CMS2_k127_1474000_5 PFAM Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 444.0
CMS2_k127_1474000_6 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 415.0
CMS2_k127_1474000_7 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 357.0
CMS2_k127_1474000_8 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 333.0
CMS2_k127_1474000_9 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 325.0
CMS2_k127_1519851_0 CBS domain containing protein K03699 - - 7.535e-209 659.0
CMS2_k127_1519851_1 PFAM alpha beta hydrolase fold K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 475.0
CMS2_k127_1519851_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 437.0
CMS2_k127_1519851_3 COG4206 Outer membrane cobalamin receptor protein K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 376.0
CMS2_k127_1519851_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 326.0
CMS2_k127_1519851_5 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000007415 258.0
CMS2_k127_1519851_6 Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000000000000000000000000000000000000001667 222.0
CMS2_k127_1519851_7 Extracellular liganD-binding receptor K01999 - - 0.000000000000000000000000000000000000000007585 158.0
CMS2_k127_1526898_0 PFAM CoA-binding domain protein K09181 - - 0.0 1138.0
CMS2_k127_1526898_1 Na+/Pi-cotransporter K03324 - - 5.988e-228 719.0
CMS2_k127_1526898_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 568.0
CMS2_k127_1526898_3 coenzyme F390 synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 532.0
CMS2_k127_1526898_4 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 520.0
CMS2_k127_1526898_5 Putative heavy-metal chelation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008841 279.0
CMS2_k127_1526898_6 Universal stress protein family - - - 0.0000000000000000000000000000000000000000002157 164.0
CMS2_k127_157214_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.98e-225 703.0
CMS2_k127_157214_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.214e-198 640.0
CMS2_k127_157214_2 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 613.0
CMS2_k127_157214_3 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 506.0
CMS2_k127_157214_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 366.0
CMS2_k127_157214_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000004709 239.0
CMS2_k127_157214_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000003126 217.0
CMS2_k127_157214_7 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000129 190.0
CMS2_k127_1621295_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.205e-194 624.0
CMS2_k127_1621295_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 588.0
CMS2_k127_1621295_10 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000000000006316 195.0
CMS2_k127_1621295_11 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000004983 198.0
CMS2_k127_1621295_12 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000001026 171.0
CMS2_k127_1621295_13 Rubrerythrin - - - 0.00000000000000000000000000000001852 134.0
CMS2_k127_1621295_14 - - - - 0.000000000000000001805 93.0
CMS2_k127_1621295_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 565.0
CMS2_k127_1621295_3 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 505.0
CMS2_k127_1621295_4 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 499.0
CMS2_k127_1621295_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 490.0
CMS2_k127_1621295_6 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K07536 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 462.0
CMS2_k127_1621295_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 424.0
CMS2_k127_1621295_8 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 340.0
CMS2_k127_1621295_9 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 303.0
CMS2_k127_173508_0 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1090.0
CMS2_k127_173508_1 Extracellular liganD-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 477.0
CMS2_k127_173508_10 PFAM lipolytic protein G-D-S-L family K01073 - 3.1.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000278 243.0
CMS2_k127_173508_11 Protein of unknown function (DUF2726) - - - 0.00000000000000000000000000000000000000004271 160.0
CMS2_k127_173508_12 - - - - 0.000000000000000000004871 99.0
CMS2_k127_173508_13 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.00000009868 60.0
CMS2_k127_173508_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 455.0
CMS2_k127_173508_3 Glucose / Sorbosone dehydrogenase K00117,K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 448.0
CMS2_k127_173508_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 424.0
CMS2_k127_173508_5 Protein of unknown function (DUF808) K09781 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 408.0
CMS2_k127_173508_6 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 347.0
CMS2_k127_173508_7 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 317.0
CMS2_k127_173508_8 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 281.0
CMS2_k127_173508_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006496 258.0
CMS2_k127_1807787_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1851.0
CMS2_k127_1807787_1 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 1.569e-291 904.0
CMS2_k127_1807787_10 Tfp pilus assembly protein FimV - - - 6.725e-197 630.0
CMS2_k127_1807787_11 Cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 562.0
CMS2_k127_1807787_12 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 573.0
CMS2_k127_1807787_13 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 561.0
CMS2_k127_1807787_14 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 550.0
CMS2_k127_1807787_15 Transporter associated domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 435.0
CMS2_k127_1807787_16 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 443.0
CMS2_k127_1807787_17 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 402.0
CMS2_k127_1807787_18 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 370.0
CMS2_k127_1807787_19 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 376.0
CMS2_k127_1807787_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 3.452e-280 878.0
CMS2_k127_1807787_20 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 343.0
CMS2_k127_1807787_21 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 308.0
CMS2_k127_1807787_22 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001063 287.0
CMS2_k127_1807787_23 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001864 287.0
CMS2_k127_1807787_24 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000002057 261.0
CMS2_k127_1807787_25 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000004958 212.0
CMS2_k127_1807787_26 MerR, DNA binding - - - 0.000000000000000000000000000000000000000000000000009474 187.0
CMS2_k127_1807787_27 Lysine exporter protein LysE K11250 - - 0.000000000000000000000000000000000000000000002144 172.0
CMS2_k127_1807787_28 TIGRFAM C_GCAxxG_C_C family protein - - - 0.00000000000000000000000000000000000000000001002 172.0
CMS2_k127_1807787_29 Methyltransferase domain - - - 0.0000000000000000000003301 98.0
CMS2_k127_1807787_3 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 4.73e-260 809.0
CMS2_k127_1807787_30 - - - - 0.000000002801 72.0
CMS2_k127_1807787_31 - - - - 0.0000299 48.0
CMS2_k127_1807787_32 Staphylococcal nuclease homologues - - - 0.0003196 46.0
CMS2_k127_1807787_4 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 2.18e-230 718.0
CMS2_k127_1807787_5 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.624e-224 704.0
CMS2_k127_1807787_6 Belongs to the thiolase family K00626 - 2.3.1.9 1.863e-214 670.0
CMS2_k127_1807787_7 Belongs to the thiolase family K00626 - 2.3.1.9 4.625e-214 670.0
CMS2_k127_1807787_8 PFAM acyl-CoA dehydrogenase domain protein - - - 2.259e-211 667.0
CMS2_k127_1807787_9 Metallo-beta-lactamase superfamily - - - 3.511e-201 644.0
CMS2_k127_191116_0 formate dehydrogenase, alpha subunit K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1636.0
CMS2_k127_191116_1 PFAM peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0 1325.0
CMS2_k127_191116_10 DNA internalization-related competence protein ComEC Rec2 K02238 - - 3.669e-251 804.0
CMS2_k127_191116_11 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 1.762e-249 772.0
CMS2_k127_191116_12 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 1.365e-246 764.0
CMS2_k127_191116_13 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 1.289e-237 758.0
CMS2_k127_191116_14 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.328e-232 740.0
CMS2_k127_191116_15 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 4.025e-231 726.0
CMS2_k127_191116_16 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 603.0
CMS2_k127_191116_17 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 590.0
CMS2_k127_191116_18 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 570.0
CMS2_k127_191116_19 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 519.0
CMS2_k127_191116_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1079.0
CMS2_k127_191116_20 Bacterial extracellular solute-binding protein K05777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 522.0
CMS2_k127_191116_21 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 504.0
CMS2_k127_191116_22 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 509.0
CMS2_k127_191116_23 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 512.0
CMS2_k127_191116_24 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 513.0
CMS2_k127_191116_25 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 488.0
CMS2_k127_191116_26 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 484.0
CMS2_k127_191116_27 NADP-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 482.0
CMS2_k127_191116_28 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 464.0
CMS2_k127_191116_29 lytic murein transglycosylase B K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 434.0
CMS2_k127_191116_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1047.0
CMS2_k127_191116_30 Ligated ion channel L-glutamate- and glycine-binding site K02030,K10036 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 430.0
CMS2_k127_191116_31 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 421.0
CMS2_k127_191116_32 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 408.0
CMS2_k127_191116_33 transport system, permease component K05778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 424.0
CMS2_k127_191116_34 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 401.0
CMS2_k127_191116_35 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 395.0
CMS2_k127_191116_36 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 390.0
CMS2_k127_191116_37 Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 384.0
CMS2_k127_191116_38 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 365.0
CMS2_k127_191116_39 PFAM MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 354.0
CMS2_k127_191116_4 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0 1020.0
CMS2_k127_191116_40 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 357.0
CMS2_k127_191116_41 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 353.0
CMS2_k127_191116_42 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 350.0
CMS2_k127_191116_43 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 329.0
CMS2_k127_191116_44 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 325.0
CMS2_k127_191116_45 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 317.0
CMS2_k127_191116_46 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 313.0
CMS2_k127_191116_47 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 314.0
CMS2_k127_191116_48 Protein of unknown function (DUF455) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 298.0
CMS2_k127_191116_49 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 302.0
CMS2_k127_191116_5 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 1.2e-322 1011.0
CMS2_k127_191116_50 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003108 278.0
CMS2_k127_191116_51 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007898 269.0
CMS2_k127_191116_52 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006211 251.0
CMS2_k127_191116_53 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009323 244.0
CMS2_k127_191116_54 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000001035 253.0
CMS2_k127_191116_55 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000015 238.0
CMS2_k127_191116_56 TonB C terminal K03646 - - 0.000000000000000000000000000000000000000000000000000000000000000007209 237.0
CMS2_k127_191116_57 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000000000001153 232.0
CMS2_k127_191116_58 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000002451 223.0
CMS2_k127_191116_59 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000000000000000000001025 214.0
CMS2_k127_191116_6 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.128e-315 974.0
CMS2_k127_191116_60 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000644 216.0
CMS2_k127_191116_61 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000000000000000000001152 198.0
CMS2_k127_191116_62 ABC transporter K05779 - - 0.000000000000000000000000000000000000000000000000000005291 216.0
CMS2_k127_191116_63 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000001542 195.0
CMS2_k127_191116_64 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000002637 191.0
CMS2_k127_191116_65 system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000003907 184.0
CMS2_k127_191116_66 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000000002106 192.0
CMS2_k127_191116_67 Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000000000000007161 179.0
CMS2_k127_191116_68 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000005436 144.0
CMS2_k127_191116_69 bond formation protein DsbB K03611 - - 0.000000000000000000000000000000002848 149.0
CMS2_k127_191116_7 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 6.401e-305 944.0
CMS2_k127_191116_70 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000003166 135.0
CMS2_k127_191116_71 - - - - 0.000000000000000000000000000000023 130.0
CMS2_k127_191116_72 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000003941 122.0
CMS2_k127_191116_73 Predicted integral membrane protein (DUF2282) - - - 0.00000000000000000000000001774 120.0
CMS2_k127_191116_74 PFAM Citrate transporter - - - 0.00000000000000000000000007625 113.0
CMS2_k127_191116_75 - - - - 0.0000000000000000000003601 99.0
CMS2_k127_191116_76 PFAM Citrate transporter - - - 0.00000001204 62.0
CMS2_k127_191116_8 Tripartite tricarboxylate transporter TctA family K07793 - - 1.199e-285 883.0
CMS2_k127_191116_9 Circularly permuted ATP-grasp type 2 - - - 2.763e-269 834.0
CMS2_k127_2050242_0 PFAM carboxyl transferase K01615 - 4.1.1.70 1.264e-290 905.0
CMS2_k127_2050242_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 578.0
CMS2_k127_2050242_2 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 554.0
CMS2_k127_2050242_3 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 391.0
CMS2_k127_2050242_4 Biotin-requiring enzyme - - - 0.00000000000000000003595 98.0
CMS2_k127_2050245_0 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 491.0
CMS2_k127_2050245_1 PFAM carboxyl transferase K01615 - 4.1.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 362.0
CMS2_k127_2050245_2 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005484 248.0
CMS2_k127_2050245_3 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000001958 199.0
CMS2_k127_2050245_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000004026 104.0
CMS2_k127_2050245_5 PFAM carboxyl transferase K01615 - 4.1.1.70 0.00000000000000001 82.0
CMS2_k127_2050245_6 Putative transposase - - - 0.000000000001884 74.0
CMS2_k127_2050245_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772,K03815 - 2.4.2.28 0.00001739 54.0
CMS2_k127_2063945_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1625.0
CMS2_k127_2063945_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 6.496e-315 998.0
CMS2_k127_2063945_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002358 250.0
CMS2_k127_2063945_11 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000000000000002609 189.0
CMS2_k127_2063945_12 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000008083 169.0
CMS2_k127_2063945_13 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00001476 48.0
CMS2_k127_2063945_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.444e-209 668.0
CMS2_k127_2063945_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 569.0
CMS2_k127_2063945_4 lytic transglycosylase K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 572.0
CMS2_k127_2063945_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 432.0
CMS2_k127_2063945_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 375.0
CMS2_k127_2063945_7 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 367.0
CMS2_k127_2063945_8 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 374.0
CMS2_k127_2063945_9 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 299.0
CMS2_k127_208363_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1519.0
CMS2_k127_208363_1 Male sterility protein - - - 0.0 1124.0
CMS2_k127_208363_10 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 1.826e-202 638.0
CMS2_k127_208363_11 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 9.377e-202 639.0
CMS2_k127_208363_12 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 599.0
CMS2_k127_208363_13 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 584.0
CMS2_k127_208363_14 PFAM extracellular solute-binding protein family 1 K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 578.0
CMS2_k127_208363_15 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 586.0
CMS2_k127_208363_16 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 554.0
CMS2_k127_208363_17 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 551.0
CMS2_k127_208363_18 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 542.0
CMS2_k127_208363_19 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 540.0
CMS2_k127_208363_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.076e-272 846.0
CMS2_k127_208363_20 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 536.0
CMS2_k127_208363_21 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 539.0
CMS2_k127_208363_22 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 529.0
CMS2_k127_208363_23 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 522.0
CMS2_k127_208363_24 peptidase S1 and S6, chymotrypsin Hap K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 514.0
CMS2_k127_208363_25 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 465.0
CMS2_k127_208363_26 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 446.0
CMS2_k127_208363_27 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 452.0
CMS2_k127_208363_28 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 432.0
CMS2_k127_208363_29 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 426.0
CMS2_k127_208363_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 7.834e-266 823.0
CMS2_k127_208363_30 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 432.0
CMS2_k127_208363_31 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 421.0
CMS2_k127_208363_32 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 412.0
CMS2_k127_208363_33 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 405.0
CMS2_k127_208363_34 Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 394.0
CMS2_k127_208363_35 peptidase K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 389.0
CMS2_k127_208363_36 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 365.0
CMS2_k127_208363_37 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 372.0
CMS2_k127_208363_38 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 361.0
CMS2_k127_208363_39 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 337.0
CMS2_k127_208363_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 6.486e-250 778.0
CMS2_k127_208363_40 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 332.0
CMS2_k127_208363_41 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 331.0
CMS2_k127_208363_42 Bacterial regulatory proteins, tetR family K05501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 308.0
CMS2_k127_208363_43 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 305.0
CMS2_k127_208363_44 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001673 276.0
CMS2_k127_208363_45 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006337 273.0
CMS2_k127_208363_46 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000222 279.0
CMS2_k127_208363_47 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001743 259.0
CMS2_k127_208363_48 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000005199 251.0
CMS2_k127_208363_49 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000007661 240.0
CMS2_k127_208363_5 Multicopper oxidase K22348 - 1.16.3.3 2.037e-237 741.0
CMS2_k127_208363_50 metal-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008185 240.0
CMS2_k127_208363_51 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000000000000000000000000000000000002734 232.0
CMS2_k127_208363_52 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000000000000000000004228 223.0
CMS2_k127_208363_53 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000000000000000000000000000000309 210.0
CMS2_k127_208363_54 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000000000000000000006009 203.0
CMS2_k127_208363_55 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000000000308 191.0
CMS2_k127_208363_56 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.000000000000000000000000000000000000000000000000001102 189.0
CMS2_k127_208363_57 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000004243 160.0
CMS2_k127_208363_58 Belongs to the transcriptional regulatory Fis family K03557 - - 0.00000000000000000000000000000002674 128.0
CMS2_k127_208363_59 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000000000004274 123.0
CMS2_k127_208363_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 5.17e-231 734.0
CMS2_k127_208363_60 Copper binding periplasmic protein CusF - - - 0.0000000000000000000000006325 113.0
CMS2_k127_208363_61 Protein of unknown function (DUF721) - - - 0.000000000000000000000003076 106.0
CMS2_k127_208363_62 FAD linked oxidase domain protein - - - 0.000000000000000001759 87.0
CMS2_k127_208363_63 - - - - 0.00000000000000156 81.0
CMS2_k127_208363_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.282e-222 694.0
CMS2_k127_208363_8 Protein of unknown function (DUF1631) - - - 8.796e-220 725.0
CMS2_k127_208363_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 6.769e-214 675.0
CMS2_k127_2084539_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0 1024.0
CMS2_k127_2084539_1 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 568.0
CMS2_k127_2099118_0 PFAM glycosyl transferase family 39 - - - 5.601e-207 660.0
CMS2_k127_2099118_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 595.0
CMS2_k127_2099118_10 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001474 286.0
CMS2_k127_2099118_11 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002831 259.0
CMS2_k127_2099118_12 - - - - 0.0000000000000000000000000000000000000000000000000003572 201.0
CMS2_k127_2099118_13 Small Multidrug Resistance protein - - - 0.00000000000000000000000000000000000000000000000002034 183.0
CMS2_k127_2099118_14 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.00000000000751 70.0
CMS2_k127_2099118_2 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 605.0
CMS2_k127_2099118_3 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 502.0
CMS2_k127_2099118_4 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 456.0
CMS2_k127_2099118_5 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 430.0
CMS2_k127_2099118_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 413.0
CMS2_k127_2099118_7 Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 391.0
CMS2_k127_2099118_8 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 381.0
CMS2_k127_2099118_9 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 309.0
CMS2_k127_2147958_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1617.0
CMS2_k127_2147958_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1601.0
CMS2_k127_2147958_10 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 615.0
CMS2_k127_2147958_11 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 595.0
CMS2_k127_2147958_12 Extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 590.0
CMS2_k127_2147958_13 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 548.0
CMS2_k127_2147958_14 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 541.0
CMS2_k127_2147958_15 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 527.0
CMS2_k127_2147958_16 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 505.0
CMS2_k127_2147958_17 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 494.0
CMS2_k127_2147958_18 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 483.0
CMS2_k127_2147958_19 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 472.0
CMS2_k127_2147958_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.786e-320 987.0
CMS2_k127_2147958_20 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 473.0
CMS2_k127_2147958_21 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 463.0
CMS2_k127_2147958_22 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 443.0
CMS2_k127_2147958_23 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 445.0
CMS2_k127_2147958_24 Phosphomethylpyrimidine kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 440.0
CMS2_k127_2147958_25 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 433.0
CMS2_k127_2147958_26 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 408.0
CMS2_k127_2147958_27 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 400.0
CMS2_k127_2147958_28 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 408.0
CMS2_k127_2147958_29 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 397.0
CMS2_k127_2147958_3 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.57e-297 915.0
CMS2_k127_2147958_30 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 394.0
CMS2_k127_2147958_31 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 398.0
CMS2_k127_2147958_32 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 376.0
CMS2_k127_2147958_33 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 371.0
CMS2_k127_2147958_34 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 364.0
CMS2_k127_2147958_35 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 364.0
CMS2_k127_2147958_36 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 357.0
CMS2_k127_2147958_37 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 339.0
CMS2_k127_2147958_38 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 336.0
CMS2_k127_2147958_39 Protein of unknown function, DUF599 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 328.0
CMS2_k127_2147958_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 1.633e-296 922.0
CMS2_k127_2147958_40 Creatinine amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 315.0
CMS2_k127_2147958_41 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 302.0
CMS2_k127_2147958_42 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 308.0
CMS2_k127_2147958_43 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 295.0
CMS2_k127_2147958_44 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 304.0
CMS2_k127_2147958_45 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000041 289.0
CMS2_k127_2147958_46 HAD-hyrolase-like K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000219 288.0
CMS2_k127_2147958_47 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000008958 264.0
CMS2_k127_2147958_48 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003762 259.0
CMS2_k127_2147958_49 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005099 265.0
CMS2_k127_2147958_5 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 4.49e-288 902.0
CMS2_k127_2147958_50 Transcriptional regulator K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001101 249.0
CMS2_k127_2147958_51 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000001717 235.0
CMS2_k127_2147958_52 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000001746 237.0
CMS2_k127_2147958_53 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000003438 235.0
CMS2_k127_2147958_54 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000001272 231.0
CMS2_k127_2147958_55 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000003115 219.0
CMS2_k127_2147958_56 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000002637 209.0
CMS2_k127_2147958_57 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000005274 204.0
CMS2_k127_2147958_58 TM2 domain - - - 0.000000000000000000000000000000000000000000000000000002572 195.0
CMS2_k127_2147958_59 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000000008592 173.0
CMS2_k127_2147958_6 TIGRFAM nitrogen regulation protein NR(I) K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 1.14e-247 771.0
CMS2_k127_2147958_60 - - - - 0.000000000000000000000000000000000000000000006401 169.0
CMS2_k127_2147958_61 - - - - 0.00000000000000000000000000000000000006952 153.0
CMS2_k127_2147958_62 SURF4 family K15977 - - 0.000000000000000000000000000000000004008 143.0
CMS2_k127_2147958_63 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000004276 137.0
CMS2_k127_2147958_64 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.000000000000000000000000000006982 136.0
CMS2_k127_2147958_65 Pfam:DUF1049 K08992 - - 0.000000000000000000000000001933 117.0
CMS2_k127_2147958_66 Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.00000000000000000000003287 99.0
CMS2_k127_2147958_67 - - - - 0.0000000000000000000005335 99.0
CMS2_k127_2147958_68 Isochorismatase family - - - 0.000000000000000005086 87.0
CMS2_k127_2147958_7 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 1.018e-241 760.0
CMS2_k127_2147958_8 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 2.989e-198 626.0
CMS2_k127_2147958_9 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 619.0
CMS2_k127_2169253_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 1.06e-198 633.0
CMS2_k127_2169253_1 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 575.0
CMS2_k127_2169253_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 486.0
CMS2_k127_2169253_3 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 383.0
CMS2_k127_2169253_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 362.0
CMS2_k127_2169253_5 Belongs to the bacterial ribosomal protein bL31 family K02909 - - 0.0000000000000000000000000000000000000000000003577 167.0
CMS2_k127_2169253_6 Phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000595 157.0
CMS2_k127_2211056_0 Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 490.0
CMS2_k127_2211056_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 468.0
CMS2_k127_2211056_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 341.0
CMS2_k127_2211056_3 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 335.0
CMS2_k127_2211056_4 Glutathione S-transferase, C-terminal domain K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 311.0
CMS2_k127_2236791_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1432.0
CMS2_k127_2236791_1 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 322.0
CMS2_k127_2236791_2 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 326.0
CMS2_k127_2236791_3 Lysine exporter protein (Lyse ygga) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 295.0
CMS2_k127_2236791_4 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003992 276.0
CMS2_k127_2236791_5 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000001776 179.0
CMS2_k127_2236791_7 spore germination - - - 0.0000002364 63.0
CMS2_k127_225737_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.246e-291 908.0
CMS2_k127_225737_1 His Kinase A (phosphoacceptor) domain K07641 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 601.0
CMS2_k127_225737_10 Transcriptional regulatory protein, C terminal K07663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 338.0
CMS2_k127_225737_11 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 312.0
CMS2_k127_225737_12 Cytochrome B561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001278 259.0
CMS2_k127_225737_13 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000007262 225.0
CMS2_k127_225737_14 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000071 237.0
CMS2_k127_225737_15 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000001128 218.0
CMS2_k127_225737_16 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000002227 205.0
CMS2_k127_225737_17 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000006141 195.0
CMS2_k127_225737_18 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000001286 157.0
CMS2_k127_225737_19 PAP2 superfamily - - - 0.000000000000000000001656 105.0
CMS2_k127_225737_2 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 591.0
CMS2_k127_225737_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 567.0
CMS2_k127_225737_4 AAA domain (dynein-related subfamily) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 508.0
CMS2_k127_225737_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 467.0
CMS2_k127_225737_6 glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 437.0
CMS2_k127_225737_7 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 428.0
CMS2_k127_225737_8 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 395.0
CMS2_k127_225737_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 369.0
CMS2_k127_2336632_0 Sulfatase K01130 - 3.1.6.1 0.0 1225.0
CMS2_k127_2336632_1 Protein of unknown function (DUF1254) - - - 0.00000002817 55.0
CMS2_k127_2379165_0 TIGRFAM ribonuclease, Rne Rng family K08301 - - 2.086e-249 780.0
CMS2_k127_2379165_1 Involved in the TonB-independent uptake of proteins K03641 - - 9.052e-204 640.0
CMS2_k127_2379165_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 511.0
CMS2_k127_2379165_3 ThiF family K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 336.0
CMS2_k127_2379165_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 316.0
CMS2_k127_2379165_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004066 284.0
CMS2_k127_2379165_6 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000001931 218.0
CMS2_k127_2379165_7 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000001775 183.0
CMS2_k127_2437478_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 1.146e-209 658.0
CMS2_k127_2437478_1 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 589.0
CMS2_k127_2437478_2 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 382.0
CMS2_k127_2437478_3 - - - - 0.00000000000000000000000000000000000000000000000000000169 193.0
CMS2_k127_2437478_4 ferredoxin - - - 0.0000000000000000000000000000000000001475 145.0
CMS2_k127_2500812_0 Surface antigen K07001 - - 1.013e-272 859.0
CMS2_k127_2500812_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.426e-205 658.0
CMS2_k127_2500812_10 oxidation-reduction process K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000004251 211.0
CMS2_k127_2500812_11 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000006569 196.0
CMS2_k127_2500812_12 FCD - - - 0.000000000000000000000000000000000000000002088 164.0
CMS2_k127_2500812_13 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000001035 152.0
CMS2_k127_2500812_14 RbsD / FucU transport protein family K02431 - 5.1.3.29 0.000000000000000000000000000000000000003183 151.0
CMS2_k127_2500812_15 amidohydrolase K07045 - - 0.0000000000000000000000000000000028 141.0
CMS2_k127_2500812_16 Nitroreductase family - - - 0.00000000000000000000000006644 116.0
CMS2_k127_2500812_2 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K08295 - 6.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 606.0
CMS2_k127_2500812_3 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000787 516.0
CMS2_k127_2500812_4 Aldo/keto reductase family K00064 - 1.1.1.122 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 485.0
CMS2_k127_2500812_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 446.0
CMS2_k127_2500812_6 Amidohydrolase K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 383.0
CMS2_k127_2500812_7 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 386.0
CMS2_k127_2500812_8 NAD dependent epimerase/dehydratase family K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 347.0
CMS2_k127_2500812_9 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 308.0
CMS2_k127_2514153_0 ATPase family associated with various cellular activities (AAA) - - - 0.0 1161.0
CMS2_k127_2514153_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 2.157e-302 952.0
CMS2_k127_2514153_10 Fumarylacetoacetate (Faa) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 567.0
CMS2_k127_2514153_11 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 582.0
CMS2_k127_2514153_12 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 564.0
CMS2_k127_2514153_13 PFAM homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 558.0
CMS2_k127_2514153_14 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 534.0
CMS2_k127_2514153_15 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 518.0
CMS2_k127_2514153_16 hydrolase of the alpha K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 495.0
CMS2_k127_2514153_17 PFAM FAD linked oxidase domain protein K00104,K11472 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 488.0
CMS2_k127_2514153_18 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007539 469.0
CMS2_k127_2514153_19 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 468.0
CMS2_k127_2514153_2 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.38e-291 899.0
CMS2_k127_2514153_20 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 466.0
CMS2_k127_2514153_21 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 451.0
CMS2_k127_2514153_22 FIST_C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 445.0
CMS2_k127_2514153_23 ATPases associated with a variety of cellular activities K02049,K15578 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 432.0
CMS2_k127_2514153_24 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 402.0
CMS2_k127_2514153_25 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 376.0
CMS2_k127_2514153_26 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 338.0
CMS2_k127_2514153_27 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 340.0
CMS2_k127_2514153_28 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003805 279.0
CMS2_k127_2514153_29 Protein of unknown function (DUF2946) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002648 266.0
CMS2_k127_2514153_3 Sodium hydrogen exchanger K03316 - - 2.552e-261 818.0
CMS2_k127_2514153_30 Beta-Ig-H3 fasciclin - - - 0.0000000000000000000000000000000000000000000000000000000000000007605 222.0
CMS2_k127_2514153_31 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000000115 229.0
CMS2_k127_2514153_32 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001852 222.0
CMS2_k127_2514153_33 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000000002906 223.0
CMS2_k127_2514153_34 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000004591 223.0
CMS2_k127_2514153_35 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000005362 222.0
CMS2_k127_2514153_36 Uncharacterised protein family (UPF0149) K07039 - - 0.000000000000000000000000000000000000000000000000000000000001054 218.0
CMS2_k127_2514153_37 - - - - 0.000000000000000000000000000000000000000000000000000000000002499 218.0
CMS2_k127_2514153_38 - - - - 0.00000000000000000000000000000000000000000000000000000000003211 212.0
CMS2_k127_2514153_39 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000000000000000000000000000000000000000000005222 207.0
CMS2_k127_2514153_4 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 3.39e-260 811.0
CMS2_k127_2514153_40 - - - - 0.0000000000000000000000000000000000000000000000000000001571 203.0
CMS2_k127_2514153_41 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000006075 195.0
CMS2_k127_2514153_42 aspartic-type endopeptidase activity K06985 - - 0.00000000000000000000000000000000000000000000000004046 197.0
CMS2_k127_2514153_43 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000000000000000000000000000000001587 169.0
CMS2_k127_2514153_44 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000000000000008333 153.0
CMS2_k127_2514153_45 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000009159 150.0
CMS2_k127_2514153_46 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000000003528 139.0
CMS2_k127_2514153_47 Zinc-finger domain - - - 0.0000000000000000000000000000001736 124.0
CMS2_k127_2514153_48 Protein of unknown function (DUF3567) - - - 0.000000000000000000000000000005057 129.0
CMS2_k127_2514153_49 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000001154 107.0
CMS2_k127_2514153_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 6.174e-245 762.0
CMS2_k127_2514153_50 - - - - 0.00000000000002471 84.0
CMS2_k127_2514153_6 Major Facilitator - - - 7.75e-226 706.0
CMS2_k127_2514153_7 4Fe-4S dicluster domain K11473 - - 1.378e-205 646.0
CMS2_k127_2514153_8 Belongs to the HypD family K04654 - - 4.824e-204 641.0
CMS2_k127_2514153_9 Diguanylate cyclase K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 617.0
CMS2_k127_2533652_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1294.0
CMS2_k127_2533652_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1102.0
CMS2_k127_2533652_10 May be involved in recombinational repair of damaged DNA K03631 - - 1.125e-215 683.0
CMS2_k127_2533652_11 Belongs to the thiolase family K00632 - 2.3.1.16 1.215e-208 657.0
CMS2_k127_2533652_12 Methionine synthase K00549 - 2.1.1.14 1.732e-200 630.0
CMS2_k127_2533652_13 Peptidase dimerisation domain - - - 2.555e-197 625.0
CMS2_k127_2533652_14 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 4.643e-197 622.0
CMS2_k127_2533652_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 599.0
CMS2_k127_2533652_16 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 556.0
CMS2_k127_2533652_17 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 534.0
CMS2_k127_2533652_18 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 536.0
CMS2_k127_2533652_19 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 501.0
CMS2_k127_2533652_2 glutamate synthase, alpha subunit domain protein K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1077.0
CMS2_k127_2533652_20 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 496.0
CMS2_k127_2533652_21 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 467.0
CMS2_k127_2533652_22 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 471.0
CMS2_k127_2533652_23 Putative aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 466.0
CMS2_k127_2533652_24 KR domain K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 457.0
CMS2_k127_2533652_25 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 457.0
CMS2_k127_2533652_26 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 449.0
CMS2_k127_2533652_27 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 437.0
CMS2_k127_2533652_28 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 432.0
CMS2_k127_2533652_29 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 428.0
CMS2_k127_2533652_3 acyl-CoA dehydrogenase - - - 0.0 1042.0
CMS2_k127_2533652_30 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 417.0
CMS2_k127_2533652_31 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 414.0
CMS2_k127_2533652_32 PFAM helix-turn-helix protein RpiR K19337 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 414.0
CMS2_k127_2533652_33 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 393.0
CMS2_k127_2533652_34 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 392.0
CMS2_k127_2533652_35 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 388.0
CMS2_k127_2533652_36 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 359.0
CMS2_k127_2533652_37 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 343.0
CMS2_k127_2533652_38 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 347.0
CMS2_k127_2533652_39 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 347.0
CMS2_k127_2533652_4 Neisseria PilC beta-propeller domain K02674 - - 6.101e-288 928.0
CMS2_k127_2533652_40 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 336.0
CMS2_k127_2533652_41 Bacterial transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 343.0
CMS2_k127_2533652_42 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 315.0
CMS2_k127_2533652_43 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 313.0
CMS2_k127_2533652_44 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 311.0
CMS2_k127_2533652_45 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 292.0
CMS2_k127_2533652_46 toluene tolerance K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 289.0
CMS2_k127_2533652_47 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002109 270.0
CMS2_k127_2533652_48 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001458 277.0
CMS2_k127_2533652_49 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000001885 253.0
CMS2_k127_2533652_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 8.312e-277 863.0
CMS2_k127_2533652_50 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002793 264.0
CMS2_k127_2533652_51 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000001449 230.0
CMS2_k127_2533652_52 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000002087 240.0
CMS2_k127_2533652_53 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000001415 232.0
CMS2_k127_2533652_54 Haloacid dehalogenase-like hydrolase K07025,K20866 - 3.1.3.10 0.000000000000000000000000000000000000000000000000000000000000003406 222.0
CMS2_k127_2533652_55 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000000000000000001884 197.0
CMS2_k127_2533652_56 outer membrane lipoprotein K06077 - - 0.0000000000000000000000000000000000000000000000000000147 193.0
CMS2_k127_2533652_57 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000002205 166.0
CMS2_k127_2533652_58 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000000000000000000000000006513 167.0
CMS2_k127_2533652_59 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000000000000000000000000000000000000000009487 159.0
CMS2_k127_2533652_6 Belongs to the GPI family K01810 - 5.3.1.9 2.002e-276 860.0
CMS2_k127_2533652_60 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000000000000000000000000000002482 155.0
CMS2_k127_2533652_61 Type II transport protein GspH K08084 - - 0.0000000000000000000000000000000000000002352 164.0
CMS2_k127_2533652_62 Pilus assembly protein PilX - - - 0.0000000000000000000000000000000000000005134 159.0
CMS2_k127_2533652_63 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000000000000000000000000002132 158.0
CMS2_k127_2533652_64 acyl-coA-binding protein - - - 0.000000000000000000000000000000000000006579 147.0
CMS2_k127_2533652_65 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000000000000005938 144.0
CMS2_k127_2533652_66 type IV pilus modification protein PilV K02671 - - 0.000000000000000000000000000009213 123.0
CMS2_k127_2533652_67 Protein of unknown function (DUF2905) - - - 0.0000000000000000000000001809 109.0
CMS2_k127_2533652_68 STAS domain K07122 - - 0.000000000000001863 82.0
CMS2_k127_2533652_69 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000002657 73.0
CMS2_k127_2533652_7 Dynamin family - - - 9.927e-239 760.0
CMS2_k127_2533652_8 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 5.712e-227 709.0
CMS2_k127_2533652_9 Protein of unknown function (DUF1298) - - - 6.265e-221 696.0
CMS2_k127_2610826_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 3061.0
CMS2_k127_2610826_1 Phenol hydroxylase, C-terminal dimerisation domain K03380,K19065 - 1.14.13.23,1.14.13.7 0.0 1110.0
CMS2_k127_2610826_10 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 426.0
CMS2_k127_2610826_11 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 426.0
CMS2_k127_2610826_12 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 377.0
CMS2_k127_2610826_13 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 309.0
CMS2_k127_2610826_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 297.0
CMS2_k127_2610826_15 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 296.0
CMS2_k127_2610826_16 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000001609 245.0
CMS2_k127_2610826_17 hydratase decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000003351 219.0
CMS2_k127_2610826_18 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000000000362 179.0
CMS2_k127_2610826_19 Type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000001051 172.0
CMS2_k127_2610826_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.056e-295 913.0
CMS2_k127_2610826_20 Tryptophan halogenase K22270 - 1.14.13.24 0.0000000000000000000000000000000000000000000468 176.0
CMS2_k127_2610826_21 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000001275 168.0
CMS2_k127_2610826_22 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000001327 159.0
CMS2_k127_2610826_23 SH3 domain - - - 0.000000000000000000000000000000000000000007031 172.0
CMS2_k127_2610826_24 tryptophan synthase subunit beta - - - 0.000000000000000000000000001047 115.0
CMS2_k127_2610826_25 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000005922 77.0
CMS2_k127_2610826_26 Rhodanese Homology Domain - - - 0.0000002493 54.0
CMS2_k127_2610826_3 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 7.558e-279 868.0
CMS2_k127_2610826_4 PFAM AMP-dependent synthetase and ligase K18661 - - 1.11e-245 767.0
CMS2_k127_2610826_5 Chromate transporter K07240 - - 8.302e-210 659.0
CMS2_k127_2610826_6 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 597.0
CMS2_k127_2610826_7 Cupin domain K00450 - 1.13.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 593.0
CMS2_k127_2610826_8 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 544.0
CMS2_k127_2610826_9 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 496.0
CMS2_k127_2748516_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1902.0
CMS2_k127_2748516_1 oxidoreductase K04090 - 1.2.7.8 0.0 1467.0
CMS2_k127_2748516_10 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 614.0
CMS2_k127_2748516_11 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 571.0
CMS2_k127_2748516_12 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 541.0
CMS2_k127_2748516_13 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 509.0
CMS2_k127_2748516_14 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 451.0
CMS2_k127_2748516_15 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 456.0
CMS2_k127_2748516_16 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 432.0
CMS2_k127_2748516_17 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 395.0
CMS2_k127_2748516_18 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 392.0
CMS2_k127_2748516_19 Protein of unknown function (DUF3445) K22342 - 1.14.13.238 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 400.0
CMS2_k127_2748516_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1132.0
CMS2_k127_2748516_20 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 374.0
CMS2_k127_2748516_21 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 381.0
CMS2_k127_2748516_22 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 359.0
CMS2_k127_2748516_23 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 357.0
CMS2_k127_2748516_24 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 355.0
CMS2_k127_2748516_25 peptidase K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 350.0
CMS2_k127_2748516_26 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 336.0
CMS2_k127_2748516_27 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 324.0
CMS2_k127_2748516_28 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 327.0
CMS2_k127_2748516_29 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 319.0
CMS2_k127_2748516_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.569e-301 937.0
CMS2_k127_2748516_30 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 318.0
CMS2_k127_2748516_31 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 308.0
CMS2_k127_2748516_32 Belongs to the UPF0502 family K09915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003045 274.0
CMS2_k127_2748516_33 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004113 259.0
CMS2_k127_2748516_34 response regulator K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008148 255.0
CMS2_k127_2748516_35 Thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000002408 229.0
CMS2_k127_2748516_36 Haem-degrading K11477 - - 0.0000000000000000000000000000000000000000000000000000000005895 205.0
CMS2_k127_2748516_37 CRS1_YhbY K07574 - - 0.000000000000000000000000000000000000000000000000000000004101 203.0
CMS2_k127_2748516_38 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000867 185.0
CMS2_k127_2748516_39 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000000002482 155.0
CMS2_k127_2748516_4 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 3.88e-299 924.0
CMS2_k127_2748516_40 Domain of unknown function (DUF4149) - - - 0.000000000000000000000000000000000201 145.0
CMS2_k127_2748516_41 Putative regulatory protein - - - 0.000000000000000000008964 94.0
CMS2_k127_2748516_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.123e-218 690.0
CMS2_k127_2748516_6 peptidylprolyl isomerase K03770 - 5.2.1.8 1.369e-218 696.0
CMS2_k127_2748516_7 Histidine kinase-like ATPases - - - 5.499e-214 689.0
CMS2_k127_2748516_8 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 1.137e-209 659.0
CMS2_k127_2748516_9 Belongs to the CarA family K01956 - 6.3.5.5 2.195e-199 629.0
CMS2_k127_2763074_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1236.0
CMS2_k127_2763074_1 Protein of unknown function (DUF1631) - - - 3.486e-297 929.0
CMS2_k127_2763074_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 411.0
CMS2_k127_2763074_11 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 386.0
CMS2_k127_2763074_12 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 346.0
CMS2_k127_2763074_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001155 280.0
CMS2_k127_2763074_14 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000005553 254.0
CMS2_k127_2763074_15 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001023 244.0
CMS2_k127_2763074_16 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003253 255.0
CMS2_k127_2763074_17 lipase activity - - - 0.0000000000000000000000000000000000000000000000000000004751 205.0
CMS2_k127_2763074_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 5.794e-262 812.0
CMS2_k127_2763074_3 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 8.347e-201 629.0
CMS2_k127_2763074_4 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 539.0
CMS2_k127_2763074_5 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 531.0
CMS2_k127_2763074_6 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 494.0
CMS2_k127_2763074_7 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 475.0
CMS2_k127_2763074_8 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 451.0
CMS2_k127_2763074_9 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 451.0
CMS2_k127_279285_0 CoA-substrate-specific enzyme activase - - - 0.0 1922.0
CMS2_k127_279285_1 extracellular solute-binding protein, family 5 K02035 - - 8e-310 953.0
CMS2_k127_279285_10 pfam abc1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 376.0
CMS2_k127_279285_11 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 361.0
CMS2_k127_279285_12 BFD domain protein 2Fe-2S -binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 372.0
CMS2_k127_279285_13 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 350.0
CMS2_k127_279285_14 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 325.0
CMS2_k127_279285_15 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 319.0
CMS2_k127_279285_16 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032,K02034,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 304.0
CMS2_k127_279285_17 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 299.0
CMS2_k127_279285_18 Ribosomal RNA adenine dimethylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005457 241.0
CMS2_k127_279285_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.0000000000000000000000000000000000000000000000000000000000001131 222.0
CMS2_k127_279285_2 Oxidoreductase domain protein - - - 3.145e-251 784.0
CMS2_k127_279285_20 - - - - 0.0000000000000000000000000000000000000000000000000000000005436 209.0
CMS2_k127_279285_22 PFAM Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000002186 158.0
CMS2_k127_279285_23 rhamnose metabolic process - - - 0.0000000000000000000000000000000001745 140.0
CMS2_k127_279285_24 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000001822 131.0
CMS2_k127_279285_25 SnoaL-like domain - - - 0.00000000000000000000000783 111.0
CMS2_k127_279285_26 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000003346 100.0
CMS2_k127_279285_27 Cytochrome B561 K12262 - - 0.0000000000000000004122 87.0
CMS2_k127_279285_29 Protein of unknown function (DUF1161) - - - 0.00000000000000002625 91.0
CMS2_k127_279285_3 Belongs to the peptidase S8 family - - - 2.256e-198 638.0
CMS2_k127_279285_30 FAD linked oxidase domain protein - - - 0.000000000000001101 87.0
CMS2_k127_279285_31 Protein of unknown function (DUF2845) - - - 0.00000000000002744 82.0
CMS2_k127_279285_4 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 556.0
CMS2_k127_279285_5 Belongs to the ABC transporter superfamily K02032,K12372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 537.0
CMS2_k127_279285_6 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 535.0
CMS2_k127_279285_7 PFAM Mandelate racemase muconate lactonizing K01856,K02549 - 4.2.1.113,5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 552.0
CMS2_k127_279285_8 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 524.0
CMS2_k127_279285_9 LysR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 429.0
CMS2_k127_2856817_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 4.455e-289 917.0
CMS2_k127_2856817_1 Tripartite tricarboxylate transporter TctA family - - - 1.851e-270 841.0
CMS2_k127_2856817_10 acetylesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 434.0
CMS2_k127_2856817_11 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 415.0
CMS2_k127_2856817_12 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 422.0
CMS2_k127_2856817_13 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 407.0
CMS2_k127_2856817_14 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 382.0
CMS2_k127_2856817_15 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 354.0
CMS2_k127_2856817_16 Enoyl-(Acyl carrier protein) reductase K22185 - 1.1.1.175 0.0000000000000000000000000000000000000000000000000000000000000000000000000000841 271.0
CMS2_k127_2856817_18 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001916 244.0
CMS2_k127_2856817_19 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000001856 229.0
CMS2_k127_2856817_2 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 3.996e-264 826.0
CMS2_k127_2856817_20 PFAM cytochrome c class I - - - 0.000000000000000000000000000000000000000000000000001187 192.0
CMS2_k127_2856817_21 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000000008556 181.0
CMS2_k127_2856817_22 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000118 180.0
CMS2_k127_2856817_23 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000006121 151.0
CMS2_k127_2856817_25 Cold shock protein K03704 - - 0.000000000000000000000000000003639 126.0
CMS2_k127_2856817_26 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000007045 115.0
CMS2_k127_2856817_27 - - - - 0.000000000000006149 79.0
CMS2_k127_2856817_28 - - - - 0.000000000002644 72.0
CMS2_k127_2856817_29 - - - - 0.0000000000271 66.0
CMS2_k127_2856817_3 Universal stress protein family K07090 - - 6.014e-204 653.0
CMS2_k127_2856817_30 COG3000 Sterol desaturase - - - 0.0000000004591 67.0
CMS2_k127_2856817_4 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 594.0
CMS2_k127_2856817_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 555.0
CMS2_k127_2856817_6 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 549.0
CMS2_k127_2856817_7 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 532.0
CMS2_k127_2856817_8 Formyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 492.0
CMS2_k127_2856817_9 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 468.0
CMS2_k127_2946316_0 acetylornithine K00821 - 2.6.1.11,2.6.1.17 1.088e-218 684.0
CMS2_k127_2946316_1 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 603.0
CMS2_k127_2946316_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 572.0
CMS2_k127_2946316_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 534.0
CMS2_k127_2946316_4 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 313.0
CMS2_k127_2946316_5 Peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000004022 222.0
CMS2_k127_2946316_6 Smr domain - - - 0.00000000000000000000000000000000000000000000000000000001292 216.0
CMS2_k127_2946316_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000004749 194.0
CMS2_k127_2946316_8 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000009242 143.0
CMS2_k127_2999266_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1151.0
CMS2_k127_2999266_1 TonB dependent receptor K02014 - - 5.635e-274 865.0
CMS2_k127_2999266_10 Mut7-C ubiquitin - - - 0.0000000000000000000000000000001604 125.0
CMS2_k127_2999266_11 - - - - 0.0000000000000000000000000000005502 124.0
CMS2_k127_2999266_12 - - - - 0.000000000000000000000000003559 118.0
CMS2_k127_2999266_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 9.13e-234 728.0
CMS2_k127_2999266_3 PFAM peptidase M61 domain protein - - - 9.586e-233 734.0
CMS2_k127_2999266_4 Pyridine nucleotide-disulphide oxidoreductase - - - 1.674e-209 660.0
CMS2_k127_2999266_5 PBP superfamily domain K07219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 497.0
CMS2_k127_2999266_6 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 389.0
CMS2_k127_2999266_7 4Fe-4S dicluster domain K05796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 329.0
CMS2_k127_2999266_8 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005974 280.0
CMS2_k127_2999266_9 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000006028 198.0
CMS2_k127_3080523_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1548.0
CMS2_k127_3080523_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1042.0
CMS2_k127_3080523_10 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 5.561e-244 770.0
CMS2_k127_3080523_11 Histidine kinase K07638 - 2.7.13.3 7.44e-214 672.0
CMS2_k127_3080523_12 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 3.258e-201 631.0
CMS2_k127_3080523_13 Cys Met metabolism pyridoxal-phosphate-dependent K01760 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 575.0
CMS2_k127_3080523_14 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 548.0
CMS2_k127_3080523_15 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 550.0
CMS2_k127_3080523_16 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 494.0
CMS2_k127_3080523_17 PFAM response regulator receiver K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 449.0
CMS2_k127_3080523_18 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 422.0
CMS2_k127_3080523_19 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 412.0
CMS2_k127_3080523_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 5.249e-310 966.0
CMS2_k127_3080523_20 KR domain K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 410.0
CMS2_k127_3080523_21 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 381.0
CMS2_k127_3080523_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 326.0
CMS2_k127_3080523_23 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 322.0
CMS2_k127_3080523_24 Roadblock/LC7 domain K07131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 310.0
CMS2_k127_3080523_25 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 282.0
CMS2_k127_3080523_26 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002777 266.0
CMS2_k127_3080523_27 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002858 256.0
CMS2_k127_3080523_28 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000009517 254.0
CMS2_k127_3080523_29 Polyhydroxyalkanoate synthesis repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002264 258.0
CMS2_k127_3080523_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.883e-305 954.0
CMS2_k127_3080523_30 cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000000000000000000008612 218.0
CMS2_k127_3080523_31 Protein of unknown function (DUF541) - - - 0.0000000000000000000000000000000000000000000000000000000000015 218.0
CMS2_k127_3080523_32 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000000000000001747 164.0
CMS2_k127_3080523_33 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000007884 157.0
CMS2_k127_3080523_34 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000000001687 142.0
CMS2_k127_3080523_35 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000001358 135.0
CMS2_k127_3080523_36 Belongs to the UPF0125 (RnfH) family K03154,K09801 - - 0.0000000000000000000002908 100.0
CMS2_k127_3080523_4 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.06e-295 914.0
CMS2_k127_3080523_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.975e-288 893.0
CMS2_k127_3080523_6 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.558e-269 846.0
CMS2_k127_3080523_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 1.861e-263 814.0
CMS2_k127_3080523_8 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 5.061e-253 785.0
CMS2_k127_3080523_9 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 9.271e-248 803.0
CMS2_k127_3081639_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 549.0
CMS2_k127_3081639_1 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001078 270.0
CMS2_k127_3081639_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001032 274.0
CMS2_k127_3081639_3 Belongs to the DsbB family K03611 - - 0.000000000000000000000000000000000000000000000001469 180.0
CMS2_k127_3081639_4 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000008574 186.0
CMS2_k127_3081639_5 Methylmuconolactone methyl-isomerase - - - 0.0000000000000000000000000000022 130.0
CMS2_k127_3081639_6 Adenylate cyclase - - - 0.000000000000000000000000001461 116.0
CMS2_k127_3081639_7 Psort location Cytoplasmic, score - - - 0.0001282 46.0
CMS2_k127_3090786_0 Sulfatase K01130 - 3.1.6.1 5.526e-307 943.0
CMS2_k127_3090786_1 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.942e-284 900.0
CMS2_k127_3090786_10 Peptidase family U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 565.0
CMS2_k127_3090786_11 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 490.0
CMS2_k127_3090786_12 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 499.0
CMS2_k127_3090786_13 Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 496.0
CMS2_k127_3090786_14 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008538 453.0
CMS2_k127_3090786_15 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 435.0
CMS2_k127_3090786_16 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 425.0
CMS2_k127_3090786_17 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 407.0
CMS2_k127_3090786_18 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 390.0
CMS2_k127_3090786_19 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 358.0
CMS2_k127_3090786_2 PFAM Glycoside hydrolase family 65, central catalytic - - - 9.552e-282 880.0
CMS2_k127_3090786_20 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 323.0
CMS2_k127_3090786_21 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 336.0
CMS2_k127_3090786_22 COG4313 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 312.0
CMS2_k127_3090786_23 AsmA family K07289,K07290 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 319.0
CMS2_k127_3090786_24 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 322.0
CMS2_k127_3090786_25 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 295.0
CMS2_k127_3090786_26 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003782 290.0
CMS2_k127_3090786_27 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001423 275.0
CMS2_k127_3090786_28 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005547 261.0
CMS2_k127_3090786_29 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004437 245.0
CMS2_k127_3090786_3 TRAP dicarboxylate transporter, DctM subunit K03299 - - 2.017e-266 835.0
CMS2_k127_3090786_30 MltA-interacting protein MipA K07274 - - 0.00000000000000000000000000000000000000000000000000000000000001562 228.0
CMS2_k127_3090786_31 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000004549 213.0
CMS2_k127_3090786_32 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000000000000000000000000001237 217.0
CMS2_k127_3090786_33 serine-type endopeptidase inhibitor activity K08276 GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0010466,GO:0010605,GO:0010951,GO:0019222,GO:0019538,GO:0030162,GO:0030234,GO:0030288,GO:0030313,GO:0030414,GO:0031323,GO:0031324,GO:0031975,GO:0032268,GO:0032269,GO:0042597,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044464,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0071704,GO:0080090,GO:0098772,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000003585 203.0
CMS2_k127_3090786_34 cyclic nucleotide binding K01420,K10914 - - 0.000000000000000000000000000000000000000000000000000000579 203.0
CMS2_k127_3090786_35 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000006742 201.0
CMS2_k127_3090786_36 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000003418 196.0
CMS2_k127_3090786_37 - - - - 0.000000000000000000000000000000000000000000000000000008899 191.0
CMS2_k127_3090786_38 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.00000000000000000000000000000000000000000000000001019 186.0
CMS2_k127_3090786_39 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000006473 180.0
CMS2_k127_3090786_4 Iron-sulfur cluster-binding domain K06871 - - 2.957e-254 793.0
CMS2_k127_3090786_40 membrane - - - 0.000000000000000000000000000000000000000000000136 173.0
CMS2_k127_3090786_41 Domain of unknown function (DUF202) K00389 - - 0.0000000000000000000000000000000000000000000003112 171.0
CMS2_k127_3090786_42 DsrE/DsrF-like family - - - 0.00000000000000000000000000000001224 135.0
CMS2_k127_3090786_43 SnoaL-like domain - - - 0.000000000000000000000007162 105.0
CMS2_k127_3090786_44 - - - - 0.0000000000000000000009427 104.0
CMS2_k127_3090786_45 cheY-homologous receiver domain - - - 0.00000000000000005109 89.0
CMS2_k127_3090786_46 Periplasmic lysozyme inhibitor of I-type lysozyme - - - 0.00000000000001057 80.0
CMS2_k127_3090786_47 Carboxymuconolactone decarboxylase family - - - 0.000000000003215 68.0
CMS2_k127_3090786_48 Putative zinc-finger - - - 0.00000005931 65.0
CMS2_k127_3090786_49 surface antigen - - - 0.000005617 53.0
CMS2_k127_3090786_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 8.103e-230 723.0
CMS2_k127_3090786_6 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 5.014e-220 699.0
CMS2_k127_3090786_7 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 3.768e-203 640.0
CMS2_k127_3090786_8 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 9.911e-199 625.0
CMS2_k127_3090786_9 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 2.485e-195 629.0
CMS2_k127_3110653_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 584.0
CMS2_k127_3110653_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 510.0
CMS2_k127_3110653_2 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 409.0
CMS2_k127_3110653_3 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 390.0
CMS2_k127_3110653_4 FecR protein - - - 0.00000000000000000000000000000000000000000000000001682 190.0
CMS2_k127_3110653_5 PFAM response regulator receiver K11443 - - 0.00000000000000000000000000000000000000000000009424 185.0
CMS2_k127_3170951_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 587.0
CMS2_k127_3170951_1 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 541.0
CMS2_k127_3170951_2 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 416.0
CMS2_k127_3170951_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 296.0
CMS2_k127_3170951_4 Nudix hydrolase K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000000000000000002335 245.0
CMS2_k127_3170951_5 Protein of unknown function (DUF805) - - - 0.0000000000000000000000000000001719 126.0
CMS2_k127_31731_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 2181.0
CMS2_k127_31731_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1639.0
CMS2_k127_31731_10 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 5.131e-249 774.0
CMS2_k127_31731_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 1.031e-245 769.0
CMS2_k127_31731_12 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 6.347e-231 729.0
CMS2_k127_31731_13 AAA domain - - - 5.425e-224 730.0
CMS2_k127_31731_14 PFAM acyl-CoA dehydrogenase domain protein - - - 4.416e-217 692.0
CMS2_k127_31731_15 response regulator K02481 - - 3.256e-216 684.0
CMS2_k127_31731_16 Homospermidine synthase K00808 - 2.5.1.44 6.427e-205 652.0
CMS2_k127_31731_17 RmuC family K09760 - - 2.651e-197 628.0
CMS2_k127_31731_18 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 559.0
CMS2_k127_31731_19 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 544.0
CMS2_k127_31731_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1618.0
CMS2_k127_31731_20 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 554.0
CMS2_k127_31731_21 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 547.0
CMS2_k127_31731_22 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 539.0
CMS2_k127_31731_23 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 528.0
CMS2_k127_31731_24 Histidine kinase K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 529.0
CMS2_k127_31731_25 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 525.0
CMS2_k127_31731_26 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 503.0
CMS2_k127_31731_27 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 495.0
CMS2_k127_31731_28 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 491.0
CMS2_k127_31731_29 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 473.0
CMS2_k127_31731_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1247.0
CMS2_k127_31731_30 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 465.0
CMS2_k127_31731_31 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 456.0
CMS2_k127_31731_32 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 456.0
CMS2_k127_31731_33 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 462.0
CMS2_k127_31731_34 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 451.0
CMS2_k127_31731_35 PFAM peptidase S58 DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 404.0
CMS2_k127_31731_36 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008751 406.0
CMS2_k127_31731_37 Regulator K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 386.0
CMS2_k127_31731_38 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 399.0
CMS2_k127_31731_39 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 385.0
CMS2_k127_31731_4 PFAM ATP-binding region, ATPase domain protein - - - 0.0 1152.0
CMS2_k127_31731_40 Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 380.0
CMS2_k127_31731_41 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 377.0
CMS2_k127_31731_42 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 368.0
CMS2_k127_31731_43 Predicted metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 368.0
CMS2_k127_31731_44 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 368.0
CMS2_k127_31731_45 Oxidoreductase family, C-terminal alpha/beta domain K00010,K18067 - 1.1.1.18,1.1.1.369,1.3.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 355.0
CMS2_k127_31731_46 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 344.0
CMS2_k127_31731_47 2OG-Fe dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 333.0
CMS2_k127_31731_48 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 327.0
CMS2_k127_31731_49 Nudix hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 305.0
CMS2_k127_31731_5 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1013.0
CMS2_k127_31731_50 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 296.0
CMS2_k127_31731_51 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004068 281.0
CMS2_k127_31731_52 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001292 274.0
CMS2_k127_31731_53 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001512 257.0
CMS2_k127_31731_54 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002544 259.0
CMS2_k127_31731_55 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000002237 258.0
CMS2_k127_31731_56 PFAM PEBP family protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003964 243.0
CMS2_k127_31731_57 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000002182 240.0
CMS2_k127_31731_58 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000319 243.0
CMS2_k127_31731_59 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000000000000000000000000000000000001155 232.0
CMS2_k127_31731_6 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 1.671e-289 899.0
CMS2_k127_31731_60 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006137 246.0
CMS2_k127_31731_61 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000002415 236.0
CMS2_k127_31731_62 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000005774 237.0
CMS2_k127_31731_63 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001021 220.0
CMS2_k127_31731_64 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000004587 217.0
CMS2_k127_31731_65 Psort location CytoplasmicMembrane, score K09793 - - 0.0000000000000000000000000000000000000000000000000000000001446 208.0
CMS2_k127_31731_66 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000000000000003463 203.0
CMS2_k127_31731_67 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000007623 193.0
CMS2_k127_31731_68 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000000000000002336 185.0
CMS2_k127_31731_69 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000000000007821 207.0
CMS2_k127_31731_7 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.386e-270 842.0
CMS2_k127_31731_70 Glutaredoxin - - - 0.000000000000000000000000000000000000000000001257 174.0
CMS2_k127_31731_71 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000001053 166.0
CMS2_k127_31731_72 Pfam Response regulator receiver - - - 0.00000000000000000000000000000000000000000007433 171.0
CMS2_k127_31731_73 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000009025 155.0
CMS2_k127_31731_74 Putative prokaryotic signal transducing protein - - - 0.00000000000000000000000000000000002625 144.0
CMS2_k127_31731_75 Protein of unknown function (DUF2788) - - - 0.000000000000000000000000000006378 119.0
CMS2_k127_31731_76 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000002365 94.0
CMS2_k127_31731_77 PFAM TPR repeat-containing protein - - - 0.0000000000001293 82.0
CMS2_k127_31731_78 - - - - 0.000000000001244 76.0
CMS2_k127_31731_79 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000002121 70.0
CMS2_k127_31731_8 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.381e-253 789.0
CMS2_k127_31731_80 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.000000004559 65.0
CMS2_k127_31731_81 LTXXQ motif family protein - - - 0.000000008938 64.0
CMS2_k127_31731_82 Thioredoxin-like K01829 - 5.3.4.1 0.000001493 56.0
CMS2_k127_31731_83 Belongs to the peptidase M50B family - - - 0.000003276 55.0
CMS2_k127_31731_9 ABC1 family K03688 - - 7.109e-250 784.0
CMS2_k127_3201518_0 AMP-binding enzyme K01895 - 6.2.1.1 3.199e-274 856.0
CMS2_k127_3201518_1 Bacterial protein of unknown function (DUF853) K06915 - - 3.068e-261 811.0
CMS2_k127_3201518_10 EamA-like transporter family K15270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 320.0
CMS2_k127_3201518_11 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001456 281.0
CMS2_k127_3201518_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004293 279.0
CMS2_k127_3201518_13 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000006245 239.0
CMS2_k127_3201518_14 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000009009 222.0
CMS2_k127_3201518_15 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000000000000000000008495 207.0
CMS2_k127_3201518_16 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000001483 219.0
CMS2_k127_3201518_17 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000000000004899 192.0
CMS2_k127_3201518_18 aminopeptidase N K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000578 165.0
CMS2_k127_3201518_2 Belongs to the GARS family K01945 - 6.3.4.13 2.626e-212 667.0
CMS2_k127_3201518_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 4.412e-199 625.0
CMS2_k127_3201518_4 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 531.0
CMS2_k127_3201518_5 SMART phosphoesterase PHP domain protein K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 436.0
CMS2_k127_3201518_6 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 426.0
CMS2_k127_3201518_7 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 400.0
CMS2_k127_3201518_8 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 364.0
CMS2_k127_3201518_9 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 327.0
CMS2_k127_3205291_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1189.0
CMS2_k127_3205291_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1149.0
CMS2_k127_3205291_10 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 584.0
CMS2_k127_3205291_11 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 569.0
CMS2_k127_3205291_12 Transporter K11688,K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 567.0
CMS2_k127_3205291_13 PFAM alpha beta hydrolase fold K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 550.0
CMS2_k127_3205291_14 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 501.0
CMS2_k127_3205291_15 PFAM fumarylacetoacetate (FAA) hydrolase K18336 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 500.0
CMS2_k127_3205291_16 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 501.0
CMS2_k127_3205291_17 pfkB family carbohydrate kinase K03338 - 2.7.1.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 467.0
CMS2_k127_3205291_18 6-phosphogluconate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 453.0
CMS2_k127_3205291_19 Helix-turn-helix type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 418.0
CMS2_k127_3205291_2 D-galactarate dehydratase Altronate hydrolase K01685,K16846 - 4.2.1.7,4.4.1.24 3.533e-271 841.0
CMS2_k127_3205291_20 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 359.0
CMS2_k127_3205291_21 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 349.0
CMS2_k127_3205291_22 regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 357.0
CMS2_k127_3205291_23 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases K18335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 345.0
CMS2_k127_3205291_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 340.0
CMS2_k127_3205291_25 Gluconolactonase K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 326.0
CMS2_k127_3205291_26 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 320.0
CMS2_k127_3205291_27 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 325.0
CMS2_k127_3205291_28 Tripartite ATP-independent periplasmic transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 289.0
CMS2_k127_3205291_29 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001128 280.0
CMS2_k127_3205291_3 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 1.842e-250 779.0
CMS2_k127_3205291_30 lipoate-protein ligase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000148 267.0
CMS2_k127_3205291_31 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000000000000003015 224.0
CMS2_k127_3205291_32 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000001488 229.0
CMS2_k127_3205291_33 Shikimate kinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000000000000001496 199.0
CMS2_k127_3205291_34 - - - - 0.0000000000000000000000000000000000000000000000000000004236 197.0
CMS2_k127_3205291_35 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000000000009785 196.0
CMS2_k127_3205291_36 PFAM regulatory protein, MerR - - - 0.00000000000000000000000000000000000000000000001606 174.0
CMS2_k127_3205291_37 Thiamine-binding protein - - - 0.0000000000000000000000000000000000000000005601 160.0
CMS2_k127_3205291_38 - - - - 0.000000000000000000000000000000000000004119 157.0
CMS2_k127_3205291_39 - - - - 0.00000000000000000000000001114 124.0
CMS2_k127_3205291_4 Belongs to the mandelate racemase muconate lactonizing enzyme family K08323 - 4.2.1.8 3.324e-246 766.0
CMS2_k127_3205291_40 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000002314 120.0
CMS2_k127_3205291_41 - - - - 0.000000000000000000009043 104.0
CMS2_k127_3205291_42 dehydrogenase - - - 0.0000000009743 61.0
CMS2_k127_3205291_43 phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.000005466 51.0
CMS2_k127_3205291_44 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0001147 45.0
CMS2_k127_3205291_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 5.1e-213 664.0
CMS2_k127_3205291_6 Mannitol dehydrogenase Rossmann domain K00040 - 1.1.1.57 2.32e-199 652.0
CMS2_k127_3205291_7 Transketolase, pyrimidine binding domain K21417 - - 1.646e-198 621.0
CMS2_k127_3205291_8 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 589.0
CMS2_k127_3205291_9 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 590.0
CMS2_k127_3281349_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0 1257.0
CMS2_k127_3281349_1 PrkA AAA domain K07180 - - 0.0 1210.0
CMS2_k127_3281349_10 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 8.026e-226 711.0
CMS2_k127_3281349_11 Belongs to the UPF0229 family K09786 - - 2.823e-216 679.0
CMS2_k127_3281349_12 twitching motility protein K02670 - - 1.643e-211 665.0
CMS2_k127_3281349_13 PFAM Type II secretion system protein E K02669,K12203 - - 1.848e-210 657.0
CMS2_k127_3281349_14 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 1.042e-204 641.0
CMS2_k127_3281349_15 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 1.999e-194 609.0
CMS2_k127_3281349_16 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 612.0
CMS2_k127_3281349_17 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 611.0
CMS2_k127_3281349_18 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 565.0
CMS2_k127_3281349_19 PFAM binding-protein-dependent transport systems inner membrane component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 544.0
CMS2_k127_3281349_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1069.0
CMS2_k127_3281349_20 Transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 537.0
CMS2_k127_3281349_21 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 499.0
CMS2_k127_3281349_22 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 497.0
CMS2_k127_3281349_23 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 481.0
CMS2_k127_3281349_24 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 468.0
CMS2_k127_3281349_25 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 473.0
CMS2_k127_3281349_26 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 467.0
CMS2_k127_3281349_27 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 462.0
CMS2_k127_3281349_28 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 433.0
CMS2_k127_3281349_29 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 411.0
CMS2_k127_3281349_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.526e-310 975.0
CMS2_k127_3281349_30 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 397.0
CMS2_k127_3281349_31 Ammonia monooxygenase K07120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 371.0
CMS2_k127_3281349_32 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 362.0
CMS2_k127_3281349_33 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 355.0
CMS2_k127_3281349_34 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 338.0
CMS2_k127_3281349_35 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 317.0
CMS2_k127_3281349_36 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 326.0
CMS2_k127_3281349_37 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 325.0
CMS2_k127_3281349_38 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 308.0
CMS2_k127_3281349_39 regulatory protein Crp K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 311.0
CMS2_k127_3281349_4 SpoVR like protein K06415 - - 8.322e-305 944.0
CMS2_k127_3281349_40 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 284.0
CMS2_k127_3281349_41 Lysine exporter protein (Lyse ygga) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 289.0
CMS2_k127_3281349_43 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 287.0
CMS2_k127_3281349_44 NnrU protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009751 271.0
CMS2_k127_3281349_45 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000289 263.0
CMS2_k127_3281349_46 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003566 261.0
CMS2_k127_3281349_47 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001791 260.0
CMS2_k127_3281349_48 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003572 257.0
CMS2_k127_3281349_49 DJ-1 PfpI family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007093 246.0
CMS2_k127_3281349_5 PFAM Phospholipid glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 1.577e-299 930.0
CMS2_k127_3281349_50 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000003356 243.0
CMS2_k127_3281349_51 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000008622 244.0
CMS2_k127_3281349_52 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000005314 243.0
CMS2_k127_3281349_53 Alpha beta hydrolase K07002 - - 0.000000000000000000000000000000000000000000000000000000000000000000286 233.0
CMS2_k127_3281349_54 Dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000004864 232.0
CMS2_k127_3281349_55 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000000000689 221.0
CMS2_k127_3281349_56 ProQ/FINO family K03607 - - 0.0000000000000000000000000000000000000000000000000000000003357 211.0
CMS2_k127_3281349_57 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000000000000000000998 199.0
CMS2_k127_3281349_58 AMMECR1 - - - 0.00000000000000000000000000000000000000000000000000001663 196.0
CMS2_k127_3281349_59 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000000000000000000000000000002434 183.0
CMS2_k127_3281349_6 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.463e-296 915.0
CMS2_k127_3281349_60 Phospholipid N-methyltransferase - - - 0.000000000000000000000000000000000000000000000001297 180.0
CMS2_k127_3281349_61 Water Stress and Hypersensitive response - - - 0.000000000000000000000000000000000000000000000002941 179.0
CMS2_k127_3281349_62 - - - - 0.00000000000000000000000000000000000000000000001516 175.0
CMS2_k127_3281349_63 abc-type tungstate transport system, permease component - - - 0.0000000000000000000000000000000000000000002213 169.0
CMS2_k127_3281349_64 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000000001962 156.0
CMS2_k127_3281349_65 - - - - 0.000000000000000000000000000000001901 135.0
CMS2_k127_3281349_66 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000000000003211 126.0
CMS2_k127_3281349_67 Cytochrome c - - - 0.000000000000000000000000001658 116.0
CMS2_k127_3281349_68 - - - - 0.0000000000000000000000002958 108.0
CMS2_k127_3281349_69 Protein of unknown function (DUF2892) - - - 0.0000000000000000000002394 98.0
CMS2_k127_3281349_7 modulator of DNA gyrase K03568 - - 1.051e-277 858.0
CMS2_k127_3281349_70 Protein required for attachment to host cells - - - 0.0000000000000000000004035 102.0
CMS2_k127_3281349_71 Predicted membrane protein (DUF2061) - - - 0.000000000000000000000468 97.0
CMS2_k127_3281349_72 - - - - 0.0000000000000000000103 96.0
CMS2_k127_3281349_73 Cmp dcmp deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000001926 96.0
CMS2_k127_3281349_74 - - - - 0.0000000000005495 71.0
CMS2_k127_3281349_75 RHS protein - - - 0.000031 56.0
CMS2_k127_3281349_76 Coenzyme A transferase K01040 - 2.8.3.12 0.0000598 46.0
CMS2_k127_3281349_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 3.85e-263 825.0
CMS2_k127_3281349_9 FAD linked oxidases, C-terminal domain K00102,K03777 - 1.1.2.4,1.1.5.12 7.65e-230 719.0
CMS2_k127_3326393_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1268.0
CMS2_k127_3326393_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.463e-320 991.0
CMS2_k127_3326393_10 PFAM 20S proteasome, A and B subunits K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 444.0
CMS2_k127_3326393_11 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 446.0
CMS2_k127_3326393_12 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 421.0
CMS2_k127_3326393_13 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 394.0
CMS2_k127_3326393_14 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 368.0
CMS2_k127_3326393_15 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 339.0
CMS2_k127_3326393_16 Nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003374 275.0
CMS2_k127_3326393_17 Glutathione S-transferase, N-terminal domain K11208 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005012 259.0
CMS2_k127_3326393_18 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000002521 220.0
CMS2_k127_3326393_19 AAA domain - - - 0.00000000000000000000000000000000000000000000000000002294 193.0
CMS2_k127_3326393_2 Fumarate reductase flavoprotein C-term K00244 - 1.3.5.4 8.832e-314 968.0
CMS2_k127_3326393_20 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000000000003618 171.0
CMS2_k127_3326393_21 Fumarate reductase subunit C K00246 - - 0.0000000000000000000000000000000000000003679 157.0
CMS2_k127_3326393_22 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 - - 0.00000000000000000000000000000000000001211 154.0
CMS2_k127_3326393_23 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000001748 129.0
CMS2_k127_3326393_24 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000003528 119.0
CMS2_k127_3326393_25 Biotin-requiring enzyme - - - 0.00000000000000001766 96.0
CMS2_k127_3326393_26 - - - - 0.00006612 46.0
CMS2_k127_3326393_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 5.913e-258 797.0
CMS2_k127_3326393_4 transport system fused permease components - - - 4.669e-226 718.0
CMS2_k127_3326393_5 Cytochrome c554 and c-prime - - - 1.796e-207 670.0
CMS2_k127_3326393_6 Transketolase, C-terminal domain K21417 - - 2.634e-194 609.0
CMS2_k127_3326393_7 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 585.0
CMS2_k127_3326393_8 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 508.0
CMS2_k127_3326393_9 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 454.0
CMS2_k127_3339084_0 cysteine protease - - - 1.086e-241 773.0
CMS2_k127_3339084_1 EamA-like transporter family K15268 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 378.0
CMS2_k127_3339084_2 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002804 237.0
CMS2_k127_3339084_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000005007 185.0
CMS2_k127_3339084_4 methyltransferase - - - 0.000000000000000000000000000000551 126.0
CMS2_k127_3339084_5 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000000000000004273 109.0
CMS2_k127_3367236_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.976e-254 805.0
CMS2_k127_3367236_1 TIGRFAM Drug resistance transporter Bcr CflA subfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 611.0
CMS2_k127_3367236_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 439.0
CMS2_k127_3367236_3 Prokaryotic glutathione synthetase, ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 309.0
CMS2_k127_3367236_4 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000002332 186.0
CMS2_k127_3367236_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000002271 184.0
CMS2_k127_3367236_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000003033 92.0
CMS2_k127_33741_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 5.058e-206 644.0
CMS2_k127_33741_1 Phosphoribulokinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 545.0
CMS2_k127_33741_2 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 520.0
CMS2_k127_33741_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000005961 108.0
CMS2_k127_33741_4 Psort location Cytoplasmic, score 8.96 K01783 - 5.1.3.1 0.000000000000003777 75.0
CMS2_k127_34110_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1446.0
CMS2_k127_34110_1 Protein of unknown function - - - 0.0 1351.0
CMS2_k127_34110_10 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 6.099e-200 629.0
CMS2_k127_34110_11 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 5.835e-195 617.0
CMS2_k127_34110_12 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 598.0
CMS2_k127_34110_13 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 608.0
CMS2_k127_34110_14 Domain of unknown function (DUF4178) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 597.0
CMS2_k127_34110_15 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 574.0
CMS2_k127_34110_16 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 541.0
CMS2_k127_34110_17 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 521.0
CMS2_k127_34110_18 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 520.0
CMS2_k127_34110_19 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 511.0
CMS2_k127_34110_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1273.0
CMS2_k127_34110_20 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 510.0
CMS2_k127_34110_21 Phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 499.0
CMS2_k127_34110_22 Protein of unknown function (DUF1688) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 493.0
CMS2_k127_34110_23 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 494.0
CMS2_k127_34110_24 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 486.0
CMS2_k127_34110_25 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 477.0
CMS2_k127_34110_26 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 469.0
CMS2_k127_34110_27 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 472.0
CMS2_k127_34110_28 Alpha beta hydrolase K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 448.0
CMS2_k127_34110_29 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 444.0
CMS2_k127_34110_3 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1234.0
CMS2_k127_34110_30 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 430.0
CMS2_k127_34110_31 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 414.0
CMS2_k127_34110_32 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 414.0
CMS2_k127_34110_33 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 405.0
CMS2_k127_34110_34 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 399.0
CMS2_k127_34110_35 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 379.0
CMS2_k127_34110_36 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 374.0
CMS2_k127_34110_37 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 373.0
CMS2_k127_34110_38 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 352.0
CMS2_k127_34110_39 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 347.0
CMS2_k127_34110_4 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 8.451e-265 838.0
CMS2_k127_34110_40 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 353.0
CMS2_k127_34110_41 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 332.0
CMS2_k127_34110_42 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 334.0
CMS2_k127_34110_43 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 321.0
CMS2_k127_34110_44 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 308.0
CMS2_k127_34110_45 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783,K03815 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 295.0
CMS2_k127_34110_46 Barstar (barnase inhibitor) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 287.0
CMS2_k127_34110_47 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007262 277.0
CMS2_k127_34110_48 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003831 268.0
CMS2_k127_34110_49 Protein of unknown function (DUF3833) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001712 248.0
CMS2_k127_34110_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 1.24e-256 799.0
CMS2_k127_34110_50 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002831 245.0
CMS2_k127_34110_51 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000007124 237.0
CMS2_k127_34110_52 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000003371 228.0
CMS2_k127_34110_53 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000041 222.0
CMS2_k127_34110_54 SnoaL-like domain K01822 - 5.3.3.1 0.00000000000000000000000000000000000000000000000000000002967 199.0
CMS2_k127_34110_55 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000000000000000000000000000001727 200.0
CMS2_k127_34110_56 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000000000001235 190.0
CMS2_k127_34110_57 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000000000000000000000001607 188.0
CMS2_k127_34110_58 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000002792 179.0
CMS2_k127_34110_59 Biopolymer transport protein K03559,K03560 - - 0.00000000000000000000000000000000000000000001595 165.0
CMS2_k127_34110_6 Belongs to the 5'-nucleotidase family K01081,K17224 - 3.1.3.5 5.987e-247 773.0
CMS2_k127_34110_60 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000001295 168.0
CMS2_k127_34110_61 Ribonuclease K01167 - 3.1.27.3 0.000000000000000000000000000000000000000004092 158.0
CMS2_k127_34110_62 Rhomboid family - - - 0.00000000000000000000000000000000000000001063 161.0
CMS2_k127_34110_63 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000002447 152.0
CMS2_k127_34110_64 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000004461 105.0
CMS2_k127_34110_65 Domain of Unknown Function (DUF350) - - - 0.000000000000000000000007612 105.0
CMS2_k127_34110_66 response regulator - - - 0.0000003128 61.0
CMS2_k127_34110_68 - - - - 0.000008924 57.0
CMS2_k127_34110_7 GTP cyclohydrolase N terminal - - - 2.099e-237 737.0
CMS2_k127_34110_8 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 2.593e-216 683.0
CMS2_k127_34110_9 Flavin containing amine oxidoreductase K06954 - - 2.214e-203 640.0
CMS2_k127_3440870_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.0 1139.0
CMS2_k127_3440870_1 Domain of unknown function (DUF1974) K06445 - - 0.0 1035.0
CMS2_k127_3440870_10 PFAM Glycoside hydrolase family 65, central catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 499.0
CMS2_k127_3440870_11 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 437.0
CMS2_k127_3440870_12 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 406.0
CMS2_k127_3440870_13 Uncharacterized protein conserved in bacteria (DUF2145) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 392.0
CMS2_k127_3440870_14 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 369.0
CMS2_k127_3440870_15 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 314.0
CMS2_k127_3440870_16 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000001957 236.0
CMS2_k127_3440870_17 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000559 238.0
CMS2_k127_3440870_18 - - - - 0.000000000000000000000000000000000000000000002227 171.0
CMS2_k127_3440870_19 Universal stress protein family - - - 0.000000000000000000000000000000000000000003308 160.0
CMS2_k127_3440870_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 6.234e-243 759.0
CMS2_k127_3440870_20 - - - - 0.00000000000000000000000000000001249 134.0
CMS2_k127_3440870_22 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000001487 57.0
CMS2_k127_3440870_3 B12 binding domain - - - 1.465e-210 671.0
CMS2_k127_3440870_4 Domain of Unknown Function (DUF748) - - - 1.505e-202 676.0
CMS2_k127_3440870_5 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 578.0
CMS2_k127_3440870_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 573.0
CMS2_k127_3440870_7 Pyridoxal-dependent decarboxylase conserved domain K13745 - 4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 565.0
CMS2_k127_3440870_8 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 542.0
CMS2_k127_3440870_9 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 506.0
CMS2_k127_3449929_0 DNA topoisomerase III K03169 - 5.99.1.2 0.0 1399.0
CMS2_k127_3449929_1 PFAM extracellular solute-binding protein family 5 K12368 - - 1.265e-300 934.0
CMS2_k127_3449929_10 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000003573 254.0
CMS2_k127_3449929_11 Cysteine-rich motif following a subset of SET domains K07117 - - 0.00000000000000000000000000000000000000000000000000000000000000000002809 259.0
CMS2_k127_3449929_12 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000001034 159.0
CMS2_k127_3449929_13 Sporulation domain protein - - - 0.0000000000000000000000000000000007001 141.0
CMS2_k127_3449929_14 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000002857 106.0
CMS2_k127_3449929_2 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 556.0
CMS2_k127_3449929_3 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 529.0
CMS2_k127_3449929_4 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 496.0
CMS2_k127_3449929_5 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 472.0
CMS2_k127_3449929_6 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 394.0
CMS2_k127_3449929_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 324.0
CMS2_k127_3449929_8 Subtilase family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 315.0
CMS2_k127_3449929_9 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000287 268.0
CMS2_k127_3482832_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 2.773e-320 986.0
CMS2_k127_3482832_1 Histidine kinase - - - 3.219e-293 917.0
CMS2_k127_3482832_10 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 603.0
CMS2_k127_3482832_11 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 570.0
CMS2_k127_3482832_12 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 552.0
CMS2_k127_3482832_13 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 550.0
CMS2_k127_3482832_14 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 553.0
CMS2_k127_3482832_15 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 529.0
CMS2_k127_3482832_16 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 519.0
CMS2_k127_3482832_17 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 513.0
CMS2_k127_3482832_18 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 489.0
CMS2_k127_3482832_19 Alanine racemase K19967 - 4.1.2.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 491.0
CMS2_k127_3482832_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.61e-290 902.0
CMS2_k127_3482832_20 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 476.0
CMS2_k127_3482832_21 Amino-transferase class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 462.0
CMS2_k127_3482832_22 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 469.0
CMS2_k127_3482832_23 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 438.0
CMS2_k127_3482832_24 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 436.0
CMS2_k127_3482832_25 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 443.0
CMS2_k127_3482832_26 Enoyl-CoA hydratase/isomerase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 396.0
CMS2_k127_3482832_27 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 385.0
CMS2_k127_3482832_28 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 371.0
CMS2_k127_3482832_29 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 364.0
CMS2_k127_3482832_3 benzoyl-CoA oxygenase K15512 - 1.14.13.208 2.209e-290 895.0
CMS2_k127_3482832_30 PFAM VanZ family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 364.0
CMS2_k127_3482832_31 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 351.0
CMS2_k127_3482832_32 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 344.0
CMS2_k127_3482832_33 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 348.0
CMS2_k127_3482832_34 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 334.0
CMS2_k127_3482832_35 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 306.0
CMS2_k127_3482832_36 phosphoglycerate mutase K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 298.0
CMS2_k127_3482832_37 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 291.0
CMS2_k127_3482832_38 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 285.0
CMS2_k127_3482832_39 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007203 291.0
CMS2_k127_3482832_4 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 8.222e-289 892.0
CMS2_k127_3482832_40 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004355 272.0
CMS2_k127_3482832_41 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008929 277.0
CMS2_k127_3482832_42 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001504 265.0
CMS2_k127_3482832_43 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005484 248.0
CMS2_k127_3482832_44 Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000000000000000000000000000000000000000000000001364 221.0
CMS2_k127_3482832_45 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000000002224 217.0
CMS2_k127_3482832_46 Sensors of blue-light using FAD - - - 0.0000000000000000000000000000000000000000000000000000000003006 206.0
CMS2_k127_3482832_47 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000002986 206.0
CMS2_k127_3482832_48 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000008073 194.0
CMS2_k127_3482832_49 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000000000000000000000001314 195.0
CMS2_k127_3482832_5 Oxidoreductase NAD-binding domain K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 5.331e-235 735.0
CMS2_k127_3482832_50 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000002918 194.0
CMS2_k127_3482832_51 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000000000000000000001146 194.0
CMS2_k127_3482832_52 Phosphotransferase system, mannose fructose-specific component IIA K02821 - 2.7.1.194 0.0000000000000000000000000000000000000000000000002627 180.0
CMS2_k127_3482832_53 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000001457 173.0
CMS2_k127_3482832_54 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000003219 161.0
CMS2_k127_3482832_55 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000481 160.0
CMS2_k127_3482832_56 - - - - 0.000000000000000000000000000000000000002636 156.0
CMS2_k127_3482832_57 Protein of unknown function (DUF454) K09790 - - 0.00000000000000000000000000000000000004072 146.0
CMS2_k127_3482832_58 Domain of unknown function (DUF1840) - - - 0.000000000000000000000000000000000001066 143.0
CMS2_k127_3482832_59 Invasion gene expression up-regulator, SirB - - - 0.000000000000000000000000000000000949 147.0
CMS2_k127_3482832_6 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 2.203e-228 719.0
CMS2_k127_3482832_60 Belongs to the UPF0250 family K09158 - - 0.000000000000000000000000000000004246 131.0
CMS2_k127_3482832_62 - - - - 0.0000000000000000000006833 95.0
CMS2_k127_3482832_63 TIGRFAM phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000005437 95.0
CMS2_k127_3482832_65 Cupin 2, conserved barrel domain protein - - - 0.000000003202 60.0
CMS2_k127_3482832_67 Redoxin domain protein - - - 0.0001101 52.0
CMS2_k127_3482832_7 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 6.102e-205 643.0
CMS2_k127_3482832_8 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 614.0
CMS2_k127_3482832_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 594.0
CMS2_k127_3513740_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.052e-248 771.0
CMS2_k127_3513740_1 - - - - 0.0000000000000000000000000000000000000000000005922 177.0
CMS2_k127_3513740_2 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.000000000000000000000000000000000000000000001795 188.0
CMS2_k127_3513740_3 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000002017 152.0
CMS2_k127_3513740_4 Belongs to the ompA family K03286 - - 0.00000000000000000000000008473 115.0
CMS2_k127_3513740_5 - - - - 0.00000000000000000000005296 105.0
CMS2_k127_3513740_6 cheY-homologous receiver domain - - - 0.000001667 61.0
CMS2_k127_3562559_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 7.887e-282 890.0
CMS2_k127_3562559_1 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 467.0
CMS2_k127_3562559_10 Cytochrome c K08738 - - 0.000000000000000000001532 98.0
CMS2_k127_3562559_11 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000003503 91.0
CMS2_k127_3562559_12 Cytochrome c K08738 - - 0.0000000000000000008461 91.0
CMS2_k127_3562559_13 metal cluster binding K03497 - - 0.00000000000001378 80.0
CMS2_k127_3562559_14 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000001372 69.0
CMS2_k127_3562559_15 cytochrome - - - 0.00000001449 67.0
CMS2_k127_3562559_16 cytochrome - - - 0.00000001916 67.0
CMS2_k127_3562559_17 Domain of unknown function (DU1801) - - - 0.00007494 46.0
CMS2_k127_3562559_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 335.0
CMS2_k127_3562559_3 cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 331.0
CMS2_k127_3562559_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 315.0
CMS2_k127_3562559_5 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 291.0
CMS2_k127_3562559_6 - - - - 0.000000000000000000000000000000000000000000000003071 183.0
CMS2_k127_3562559_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000001152 127.0
CMS2_k127_3562559_8 PFAM Cytochrome C - - - 0.000000000000000000000000002444 124.0
CMS2_k127_3562559_9 PFAM Cytochrome C - - - 0.00000000000000000000002118 115.0
CMS2_k127_361324_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1805.0
CMS2_k127_361324_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1164.0
CMS2_k127_361324_10 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 385.0
CMS2_k127_361324_11 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 332.0
CMS2_k127_361324_12 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 299.0
CMS2_k127_361324_13 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 308.0
CMS2_k127_361324_14 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000000000000000000000000000000000000000002486 230.0
CMS2_k127_361324_15 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000258 221.0
CMS2_k127_361324_16 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000000003045 215.0
CMS2_k127_361324_17 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000000000000000000000000002086 205.0
CMS2_k127_361324_18 Protein of unknown function (DUF3306) - - - 0.000000000000000000000000000000007255 136.0
CMS2_k127_361324_19 - - - - 0.000000000000000000000000000000008164 133.0
CMS2_k127_361324_2 NADH ubiquinone plastoquinone (Complex I) - - - 0.0 1045.0
CMS2_k127_361324_20 - - - - 0.00000000000000000000006098 102.0
CMS2_k127_361324_21 - - - - 0.00000000004256 66.0
CMS2_k127_361324_22 - - - - 0.000000686 59.0
CMS2_k127_361324_23 Heme exporter protein D (CcmD) K02196 - - 0.0001427 48.0
CMS2_k127_361324_3 4Fe-4S dicluster domain - - - 0.0 1041.0
CMS2_k127_361324_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 608.0
CMS2_k127_361324_5 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 503.0
CMS2_k127_361324_6 Formate dehydrogenase gamma subunit K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 500.0
CMS2_k127_361324_7 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 434.0
CMS2_k127_361324_8 4Fe-4S dicluster domain K00124,K07307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 428.0
CMS2_k127_361324_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 433.0
CMS2_k127_3698599_0 Zn_pept - - - 2.289e-273 852.0
CMS2_k127_3698599_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 3.859e-268 862.0
CMS2_k127_3698599_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 591.0
CMS2_k127_3698599_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 511.0
CMS2_k127_3698599_4 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 434.0
CMS2_k127_3698599_5 Glutamine amido-transferase - - - 0.000001358 56.0
CMS2_k127_3759084_0 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 0.0 1061.0
CMS2_k127_3759084_1 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 1.179e-219 701.0
CMS2_k127_3759084_10 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000009115 192.0
CMS2_k127_3759084_11 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000002014 179.0
CMS2_k127_3759084_12 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000007299 177.0
CMS2_k127_3759084_14 - - - - 0.0000000000000000005667 91.0
CMS2_k127_3759084_15 Histidine kinase - - - 0.000000000000004326 83.0
CMS2_k127_3759084_16 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000001221 76.0
CMS2_k127_3759084_2 Belongs to the thiolase family K00626 - 2.3.1.9 6.06e-214 670.0
CMS2_k127_3759084_3 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 529.0
CMS2_k127_3759084_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 444.0
CMS2_k127_3759084_5 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 402.0
CMS2_k127_3759084_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 378.0
CMS2_k127_3759084_7 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 312.0
CMS2_k127_3759084_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008334 267.0
CMS2_k127_3759084_9 AIG2-like family - - - 0.00000000000000000000000000000000000000000000000000000000000004541 222.0
CMS2_k127_3788755_0 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 1.603e-211 698.0
CMS2_k127_3788755_1 aconitate hydratase K01681 - 4.2.1.3 9.309e-202 633.0
CMS2_k127_3788755_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 571.0
CMS2_k127_3788755_3 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 337.0
CMS2_k127_3788755_4 Shikimate dehydrogenase substrate binding domain protein K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008261 292.0
CMS2_k127_3816858_0 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 344.0
CMS2_k127_3816858_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007156 273.0
CMS2_k127_3816858_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001574 263.0
CMS2_k127_3816858_3 PFAM Cytochrome C - - - 0.0000000000000000000000000000001609 133.0
CMS2_k127_3852316_0 TRAP transporter, 4TM 12TM fusion protein - - - 1.192e-244 774.0
CMS2_k127_3852316_1 Metallopeptidase family M24 - - - 7.175e-203 644.0
CMS2_k127_3852316_2 TRAP transporter, solute receptor (TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 366.0
CMS2_k127_3852316_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 369.0
CMS2_k127_3852316_4 ABC-type nitrate sulfonate bicarbonate transport - - - 0.00000000000000000000000000000000000000000000009548 181.0
CMS2_k127_3852316_5 IstB-like ATP binding protein - - - 0.000000000000000000000008691 111.0
CMS2_k127_3852316_6 Sulphur transport K07112 - - 0.00000002354 55.0
CMS2_k127_3852316_7 Sulphur transport K07112 - - 0.000003899 48.0
CMS2_k127_3852316_8 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.0003641 43.0
CMS2_k127_4062180_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1589.0
CMS2_k127_4062180_1 Tetratricopeptide repeat - - - 0.0 1210.0
CMS2_k127_4062180_10 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 369.0
CMS2_k127_4062180_11 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 345.0
CMS2_k127_4062180_12 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 355.0
CMS2_k127_4062180_14 Amine oxidase, flavin-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 323.0
CMS2_k127_4062180_15 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004291 293.0
CMS2_k127_4062180_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008286 270.0
CMS2_k127_4062180_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004882 263.0
CMS2_k127_4062180_18 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007224 244.0
CMS2_k127_4062180_19 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000000000001504 231.0
CMS2_k127_4062180_2 Tetratricopeptide repeat - - - 5.047e-233 738.0
CMS2_k127_4062180_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001445 223.0
CMS2_k127_4062180_21 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000003066 204.0
CMS2_k127_4062180_23 - - - - 0.000000000000000000000000000000005515 136.0
CMS2_k127_4062180_24 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.000000000000000000000000000000008666 145.0
CMS2_k127_4062180_25 Cold shock protein K03704 - - 0.00000000000000000000000000000002846 130.0
CMS2_k127_4062180_26 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000009454 117.0
CMS2_k127_4062180_27 Glycosyl transferase, family 2 - - - 0.00000000000000000000000001472 121.0
CMS2_k127_4062180_28 protein histidine kinase activity K06375 - - 0.0000000000000000000007917 105.0
CMS2_k127_4062180_3 2-nitropropane dioxygenase K00459 - 1.13.12.16 1.436e-200 632.0
CMS2_k127_4062180_30 Cysteine-rich CWC - - - 0.0000000000003789 74.0
CMS2_k127_4062180_31 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000001213 71.0
CMS2_k127_4062180_32 - - - - 0.00004984 51.0
CMS2_k127_4062180_4 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 600.0
CMS2_k127_4062180_5 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 601.0
CMS2_k127_4062180_6 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 567.0
CMS2_k127_4062180_7 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 491.0
CMS2_k127_4062180_8 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 479.0
CMS2_k127_4062180_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 471.0
CMS2_k127_4074382_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1262.0
CMS2_k127_4074382_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 8.463e-255 787.0
CMS2_k127_4074382_10 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 304.0
CMS2_k127_4074382_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 281.0
CMS2_k127_4074382_12 Domain of unknown function (DUF1705) K03760 - 2.7.8.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006897 271.0
CMS2_k127_4074382_13 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002054 269.0
CMS2_k127_4074382_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000312 254.0
CMS2_k127_4074382_15 NapC/NirT cytochrome c family, N-terminal region K03532 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001191 248.0
CMS2_k127_4074382_16 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008035 255.0
CMS2_k127_4074382_17 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000004384 169.0
CMS2_k127_4074382_18 Cold shock protein K03704 - - 0.00000000000000000000000000000001802 127.0
CMS2_k127_4074382_19 membrane-associated, metal-dependent hydrolase K03760 - 2.7.8.43 0.00000000000000000000000000000002714 141.0
CMS2_k127_4074382_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 4.528e-231 721.0
CMS2_k127_4074382_20 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000007226 61.0
CMS2_k127_4074382_21 PAP2 superfamily - - - 0.00000002838 57.0
CMS2_k127_4074382_22 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.0001185 49.0
CMS2_k127_4074382_3 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 5.767e-228 712.0
CMS2_k127_4074382_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 578.0
CMS2_k127_4074382_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 445.0
CMS2_k127_4074382_6 PFAM HhH-GPD family protein K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 371.0
CMS2_k127_4074382_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 368.0
CMS2_k127_4074382_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 346.0
CMS2_k127_4074382_9 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 332.0
CMS2_k127_4077954_0 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 1.141e-246 771.0
CMS2_k127_4077954_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 607.0
CMS2_k127_4077954_2 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 467.0
CMS2_k127_4077954_3 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 463.0
CMS2_k127_4077954_4 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 437.0
CMS2_k127_4077954_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 423.0
CMS2_k127_4077954_6 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004051 259.0
CMS2_k127_4077954_7 DsrE/DsrF-like family - - - 0.00000000000000000000000000000001101 132.0
CMS2_k127_4085674_0 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1197.0
CMS2_k127_4085674_1 AAA ATPase domain - - - 1.873e-231 756.0
CMS2_k127_4085674_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 343.0
CMS2_k127_4085674_3 reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 308.0
CMS2_k127_4085674_4 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000001188 228.0
CMS2_k127_4085674_5 - - - - 0.0000000000000000000000000000000000000000001208 162.0
CMS2_k127_4085674_6 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000001327 126.0
CMS2_k127_4085674_7 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000003287 98.0
CMS2_k127_4085674_8 - - - - 0.0000000000000002797 79.0
CMS2_k127_4087854_0 Peptidase C39 family K13409 - - 7.789e-303 952.0
CMS2_k127_4087854_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.424e-271 840.0
CMS2_k127_4087854_10 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 580.0
CMS2_k127_4087854_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 532.0
CMS2_k127_4087854_12 Resolvase K06400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 480.0
CMS2_k127_4087854_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 410.0
CMS2_k127_4087854_14 HlyD family secretion protein K13408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 418.0
CMS2_k127_4087854_15 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 409.0
CMS2_k127_4087854_16 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 392.0
CMS2_k127_4087854_17 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 381.0
CMS2_k127_4087854_18 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 325.0
CMS2_k127_4087854_19 Autoinducer binding domain K07782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000011 267.0
CMS2_k127_4087854_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.923e-265 824.0
CMS2_k127_4087854_20 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000003882 211.0
CMS2_k127_4087854_21 CHASE - - - 0.00000000000000000000000000000000000000000000000002163 199.0
CMS2_k127_4087854_22 PFAM Sporulation domain protein K03749 - - 0.00000000000000000000000000000000000000000000000005812 186.0
CMS2_k127_4087854_23 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000001852 169.0
CMS2_k127_4087854_24 Protein of unknown function (DUF2924) - - - 0.000000000000611 76.0
CMS2_k127_4087854_26 Protein of unknown function (DUF3489) - - - 0.00000000001837 71.0
CMS2_k127_4087854_27 - - - - 0.000000009545 59.0
CMS2_k127_4087854_28 - - - - 0.0000005753 52.0
CMS2_k127_4087854_29 Histidine kinase - - - 0.00001059 61.0
CMS2_k127_4087854_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 1.661e-251 865.0
CMS2_k127_4087854_30 Putative transposase - - - 0.00001663 48.0
CMS2_k127_4087854_4 COG3170 Tfp pilus assembly protein FimV K08086 - - 3.229e-235 752.0
CMS2_k127_4087854_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.651e-234 731.0
CMS2_k127_4087854_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 6.252e-234 727.0
CMS2_k127_4087854_7 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 2.092e-216 676.0
CMS2_k127_4087854_8 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 3.703e-200 639.0
CMS2_k127_4087854_9 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 1.483e-199 631.0
CMS2_k127_4222961_0 Belongs to the TPP enzyme family K03852 - 2.3.3.15 0.0 1082.0
CMS2_k127_4222961_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0 1011.0
CMS2_k127_4222961_10 ABC-type sugar transport system periplasmic component K02027,K05813,K17244 - - 1.279e-223 702.0
CMS2_k127_4222961_11 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 4.168e-208 654.0
CMS2_k127_4222961_12 Citrate synthase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 573.0
CMS2_k127_4222961_13 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 576.0
CMS2_k127_4222961_14 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 526.0
CMS2_k127_4222961_15 ABC-type sugar transport system periplasmic component K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 505.0
CMS2_k127_4222961_16 TIGRFAM taurine ABC transporter, periplasmic binding protein K15551 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 501.0
CMS2_k127_4222961_17 LysR substrate binding domain K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 494.0
CMS2_k127_4222961_18 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 468.0
CMS2_k127_4222961_19 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 461.0
CMS2_k127_4222961_2 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.479e-300 925.0
CMS2_k127_4222961_20 ABC transporter K10831 - 3.6.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 461.0
CMS2_k127_4222961_21 ABC-type sugar K02025,K05814,K10118,K17242,K17245 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 455.0
CMS2_k127_4222961_22 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 453.0
CMS2_k127_4222961_23 Belongs to the LDH2 MDH2 oxidoreductase family K13609,K16844 - 1.1.1.338,1.5.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 457.0
CMS2_k127_4222961_24 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 442.0
CMS2_k127_4222961_25 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 430.0
CMS2_k127_4222961_26 TOBE domain K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 426.0
CMS2_k127_4222961_27 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 422.0
CMS2_k127_4222961_28 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 419.0
CMS2_k127_4222961_29 ABC-type sugar transport systems permease components K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 406.0
CMS2_k127_4222961_3 AMP-binding enzyme - - - 1.787e-279 872.0
CMS2_k127_4222961_30 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 406.0
CMS2_k127_4222961_31 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009449 397.0
CMS2_k127_4222961_32 UTRA domain K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 350.0
CMS2_k127_4222961_33 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 351.0
CMS2_k127_4222961_34 phosphate acetyltransferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 338.0
CMS2_k127_4222961_35 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 334.0
CMS2_k127_4222961_36 Enoyl-(Acyl carrier protein) reductase K22185 - 1.1.1.175 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 337.0
CMS2_k127_4222961_37 helix_turn _helix lactose operon repressor K02529,K06145 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 308.0
CMS2_k127_4222961_38 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 293.0
CMS2_k127_4222961_39 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 281.0
CMS2_k127_4222961_4 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 2.088e-277 859.0
CMS2_k127_4222961_40 helix_turn _helix lactose operon repressor K06145 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001098 267.0
CMS2_k127_4222961_41 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000001088 190.0
CMS2_k127_4222961_42 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000000000000000001458 187.0
CMS2_k127_4222961_43 - - - - 0.0000000000000000000000000000000000000000000000000004287 197.0
CMS2_k127_4222961_44 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000002436 190.0
CMS2_k127_4222961_45 SAF K16845 - 4.4.1.24 0.000000000000000000000000000000000000000000001024 177.0
CMS2_k127_4222961_46 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000001029 174.0
CMS2_k127_4222961_47 Redoxin - - - 0.00000000000000000000000000000001508 141.0
CMS2_k127_4222961_48 LemA family K03744 - - 0.0000000000000000000000002524 112.0
CMS2_k127_4222961_49 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000004032 87.0
CMS2_k127_4222961_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.431e-275 865.0
CMS2_k127_4222961_6 Dehydratase family K22186 - 4.2.1.82 2.365e-270 842.0
CMS2_k127_4222961_7 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 2.007e-236 736.0
CMS2_k127_4222961_8 D-galactarate dehydratase Altronate hydrolase K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 1.994e-234 727.0
CMS2_k127_4222961_9 PFAM regulatory protein GntR HTH K00375 - - 3.107e-228 716.0
CMS2_k127_4223109_0 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1954.0
CMS2_k127_4223109_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 7.506e-280 873.0
CMS2_k127_4223109_10 NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 300.0
CMS2_k127_4223109_11 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000245 184.0
CMS2_k127_4223109_12 DsrC like protein - - - 0.000000000000000000000000000000003092 132.0
CMS2_k127_4223109_13 hydrogenase maturation protease - - - 0.00000000000000000000000000000002637 131.0
CMS2_k127_4223109_15 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000005342 88.0
CMS2_k127_4223109_2 Nickel-dependent hydrogenase K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 1.753e-232 728.0
CMS2_k127_4223109_3 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 511.0
CMS2_k127_4223109_4 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 428.0
CMS2_k127_4223109_5 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 376.0
CMS2_k127_4223109_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 365.0
CMS2_k127_4223109_7 Peptidase C26 K01658,K07010 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 366.0
CMS2_k127_4223109_8 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 336.0
CMS2_k127_4223109_9 4Fe-4S single cluster domain K18006 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 339.0
CMS2_k127_4283683_0 NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1677.0
CMS2_k127_4283683_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1553.0
CMS2_k127_4283683_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.83e-265 820.0
CMS2_k127_4283683_11 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.515e-264 824.0
CMS2_k127_4283683_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.786e-256 795.0
CMS2_k127_4283683_13 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.3e-237 740.0
CMS2_k127_4283683_14 serine dehydratase beta chain K01752 - 4.3.1.17 1.687e-236 737.0
CMS2_k127_4283683_15 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.194e-236 739.0
CMS2_k127_4283683_16 PFAM Cys Met metabolism K01740 - 2.5.1.49 3.311e-236 745.0
CMS2_k127_4283683_17 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 8.62e-235 746.0
CMS2_k127_4283683_18 PFAM PHB de-polymerase domain protein K05973 - 3.1.1.75 1.69e-229 719.0
CMS2_k127_4283683_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.296e-225 708.0
CMS2_k127_4283683_2 Domain of unknown function (DUF3394) - - - 0.0 1240.0
CMS2_k127_4283683_20 Bacterial extracellular solute-binding protein K17315 - - 8.919e-217 679.0
CMS2_k127_4283683_21 PFAM FAD linked oxidase domain protein - - - 2.824e-211 668.0
CMS2_k127_4283683_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 2.96e-209 652.0
CMS2_k127_4283683_23 PFAM Aminotransferase class I and II K00832 - 2.6.1.57 1.749e-206 648.0
CMS2_k127_4283683_24 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 1.894e-202 646.0
CMS2_k127_4283683_25 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 6.204e-202 635.0
CMS2_k127_4283683_26 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 602.0
CMS2_k127_4283683_27 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 606.0
CMS2_k127_4283683_28 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 589.0
CMS2_k127_4283683_29 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 584.0
CMS2_k127_4283683_3 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1223.0
CMS2_k127_4283683_30 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 554.0
CMS2_k127_4283683_31 Glycine cleavage system T protein K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 554.0
CMS2_k127_4283683_32 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 553.0
CMS2_k127_4283683_33 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 551.0
CMS2_k127_4283683_34 ABC transporter K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 528.0
CMS2_k127_4283683_35 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 518.0
CMS2_k127_4283683_36 Binding-protein-dependent transport system inner membrane component K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 498.0
CMS2_k127_4283683_37 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 500.0
CMS2_k127_4283683_38 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 494.0
CMS2_k127_4283683_39 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 499.0
CMS2_k127_4283683_4 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1176.0
CMS2_k127_4283683_40 Binding-protein-dependent transport system inner membrane component K17317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 484.0
CMS2_k127_4283683_41 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 436.0
CMS2_k127_4283683_42 Response regulator of the LytR AlgR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 418.0
CMS2_k127_4283683_43 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 411.0
CMS2_k127_4283683_44 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 387.0
CMS2_k127_4283683_45 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 335.0
CMS2_k127_4283683_46 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 340.0
CMS2_k127_4283683_47 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 328.0
CMS2_k127_4283683_48 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 327.0
CMS2_k127_4283683_49 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 330.0
CMS2_k127_4283683_5 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1152.0
CMS2_k127_4283683_50 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 319.0
CMS2_k127_4283683_51 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 319.0
CMS2_k127_4283683_52 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 308.0
CMS2_k127_4283683_53 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 287.0
CMS2_k127_4283683_54 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001526 275.0
CMS2_k127_4283683_55 Asp Glu Hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002982 273.0
CMS2_k127_4283683_56 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005747 271.0
CMS2_k127_4283683_57 NADH dehydrogenase K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 261.0
CMS2_k127_4283683_58 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001427 267.0
CMS2_k127_4283683_59 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002758 239.0
CMS2_k127_4283683_6 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1101.0
CMS2_k127_4283683_60 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000008077 241.0
CMS2_k127_4283683_61 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000001384 234.0
CMS2_k127_4283683_62 Helix-turn-helix domain, rpiR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002491 243.0
CMS2_k127_4283683_63 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000009687 235.0
CMS2_k127_4283683_64 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001301 238.0
CMS2_k127_4283683_65 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000000000000000000000000000001436 231.0
CMS2_k127_4283683_66 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002203 222.0
CMS2_k127_4283683_67 Low molecular weight phosphotyrosine protein phosphatase K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000004346 220.0
CMS2_k127_4283683_68 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000000000000005464 216.0
CMS2_k127_4283683_69 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000003571 222.0
CMS2_k127_4283683_7 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.0 1082.0
CMS2_k127_4283683_70 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000000000008027 199.0
CMS2_k127_4283683_71 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000000000000000007206 187.0
CMS2_k127_4283683_72 Acetyltransferase (GNAT) domain K03829 - - 0.00000000000000000000000000000000000000000000000005813 184.0
CMS2_k127_4283683_73 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000000002662 176.0
CMS2_k127_4283683_74 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000007564 170.0
CMS2_k127_4283683_75 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000005467 171.0
CMS2_k127_4283683_76 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000000003675 154.0
CMS2_k127_4283683_77 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000000000001618 135.0
CMS2_k127_4283683_78 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000000000000618 134.0
CMS2_k127_4283683_79 - - - - 0.0000000000000000000000002797 109.0
CMS2_k127_4283683_8 PFAM AMP-dependent synthetase and ligase K00666 - - 1.578e-309 953.0
CMS2_k127_4283683_80 protein conserved in bacteria - - - 0.000000000000000000000001173 111.0
CMS2_k127_4283683_81 Protein of unknown function (DUF1298) - - - 0.0000000000000002768 83.0
CMS2_k127_4283683_82 Phosphopantetheine attachment site - - - 0.0000000000000003806 88.0
CMS2_k127_4283683_9 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.053e-284 887.0
CMS2_k127_4351893_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 7.331e-224 713.0
CMS2_k127_4351893_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 595.0
CMS2_k127_4351893_2 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 471.0
CMS2_k127_4351893_3 ABC-type sugar transport system, permease component K02026,K17323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 434.0
CMS2_k127_4351893_4 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 424.0
CMS2_k127_4351893_5 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 406.0
CMS2_k127_4351893_6 COG1175 ABC-type sugar transport systems permease components K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 400.0
CMS2_k127_4351893_7 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000000000000004536 141.0
CMS2_k127_4351893_8 nucleic acid-binding protein contains PIN domain - - - 0.0000000000000000000006792 97.0
CMS2_k127_4351893_9 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000001052 84.0
CMS2_k127_4353040_0 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 2.419e-210 656.0
CMS2_k127_4353040_1 PFAM Amidohydrolase 2 K10221 - 3.1.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008516 588.0
CMS2_k127_4353040_2 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 523.0
CMS2_k127_4353040_3 Domain of unknown function (DUF1932) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 462.0
CMS2_k127_4353040_4 Aldolase/RraA K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 394.0
CMS2_k127_4353040_5 Oxidoreductase K10219 - 1.1.1.312 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 356.0
CMS2_k127_4353040_6 PFAM Extradiol ring-cleavage dioxygenase LigAB LigA subunit K04100 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000004402 249.0
CMS2_k127_4353040_7 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000001398 106.0
CMS2_k127_4374595_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1292.0
CMS2_k127_4374595_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K04108 - 1.3.7.9 2.488e-302 947.0
CMS2_k127_4374595_10 NnrS protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 361.0
CMS2_k127_4374595_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 354.0
CMS2_k127_4374595_12 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 362.0
CMS2_k127_4374595_13 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04109,K11178 - 1.17.1.4,1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 346.0
CMS2_k127_4374595_14 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 340.0
CMS2_k127_4374595_15 DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 311.0
CMS2_k127_4374595_16 branched-chain amino acid transport K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 308.0
CMS2_k127_4374595_17 KR domain K00059,K21883 - 1.1.1.100,1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007028 282.0
CMS2_k127_4374595_18 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001326 266.0
CMS2_k127_4374595_19 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000502 248.0
CMS2_k127_4374595_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 596.0
CMS2_k127_4374595_20 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002894 246.0
CMS2_k127_4374595_21 Thioesterase-like superfamily K01075 - 3.1.2.23 0.0000000000000000000000000000000000000000000000000000000000000000000005785 239.0
CMS2_k127_4374595_22 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000253 243.0
CMS2_k127_4374595_23 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000004967 235.0
CMS2_k127_4374595_24 [2Fe-2S] binding domain K04107 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000001064 218.0
CMS2_k127_4374595_25 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000008219 210.0
CMS2_k127_4374595_26 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000862 197.0
CMS2_k127_4374595_27 DMSO reductase anchor subunit (DmsC) K18363 - - 0.0000000000000000000000000000000000000000000000000000426 203.0
CMS2_k127_4374595_28 Thioesterase - - - 0.0000000000000000000000000000000000000000000000000008649 186.0
CMS2_k127_4374595_29 - - - - 0.00000000000000000000000000000000000000002349 160.0
CMS2_k127_4374595_3 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 509.0
CMS2_k127_4374595_30 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000002776 156.0
CMS2_k127_4374595_31 - - - - 0.00000000000000000000000000000000000000134 152.0
CMS2_k127_4374595_32 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000001728 147.0
CMS2_k127_4374595_33 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000008232 143.0
CMS2_k127_4374595_34 transcriptional regulator - - - 0.00000000000000000000000000000000002391 139.0
CMS2_k127_4374595_35 DNA-3-methyladenine glycosylase activity K01246 - 3.2.2.20 0.0000000000000000001362 89.0
CMS2_k127_4374595_36 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000006117 92.0
CMS2_k127_4374595_37 - - - - 0.0000000003117 68.0
CMS2_k127_4374595_4 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 483.0
CMS2_k127_4374595_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 456.0
CMS2_k127_4374595_6 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 433.0
CMS2_k127_4374595_7 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 410.0
CMS2_k127_4374595_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 362.0
CMS2_k127_4374595_9 4Fe-4S binding domain K18362 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 357.0
CMS2_k127_4445891_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1470.0
CMS2_k127_4445891_1 von Willebrand factor type A domain K07114 - - 7.759e-291 913.0
CMS2_k127_4445891_10 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 430.0
CMS2_k127_4445891_11 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 352.0
CMS2_k127_4445891_12 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 346.0
CMS2_k127_4445891_13 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 329.0
CMS2_k127_4445891_14 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007943 339.0
CMS2_k127_4445891_15 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 - 1.1.1.328,2.7.7.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 324.0
CMS2_k127_4445891_16 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 319.0
CMS2_k127_4445891_17 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 305.0
CMS2_k127_4445891_18 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 312.0
CMS2_k127_4445891_19 XdhC and CoxI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 315.0
CMS2_k127_4445891_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.666e-241 746.0
CMS2_k127_4445891_20 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 304.0
CMS2_k127_4445891_21 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000005101 270.0
CMS2_k127_4445891_22 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000738 258.0
CMS2_k127_4445891_23 class II Aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002093 255.0
CMS2_k127_4445891_24 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000000000000000000002553 237.0
CMS2_k127_4445891_25 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.00000000000000000000000000000000000000000000000000000000000000002201 230.0
CMS2_k127_4445891_26 TPM domain - - - 0.00000000000000000000000000000000000000000000000000000000000002035 222.0
CMS2_k127_4445891_27 - - - - 0.00000000000000000000000000000000000000000000000000000004084 199.0
CMS2_k127_4445891_28 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000002488 203.0
CMS2_k127_4445891_29 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000001628 200.0
CMS2_k127_4445891_3 PFAM FAD linked oxidase domain protein - - - 4.25e-212 667.0
CMS2_k127_4445891_30 - - - - 0.0000000000000000000000000000000000000000000000000004032 205.0
CMS2_k127_4445891_31 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000001486 172.0
CMS2_k127_4445891_33 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000005479 160.0
CMS2_k127_4445891_34 Rieske [2Fe-2S] domain K18068 - 1.14.12.7 0.0000002909 62.0
CMS2_k127_4445891_35 EamA-like transporter family K15268 - - 0.0001665 45.0
CMS2_k127_4445891_4 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 572.0
CMS2_k127_4445891_5 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 534.0
CMS2_k127_4445891_6 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 504.0
CMS2_k127_4445891_7 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 428.0
CMS2_k127_4445891_8 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 426.0
CMS2_k127_4445891_9 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 424.0
CMS2_k127_459795_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 3447.0
CMS2_k127_459795_1 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 2.796e-209 658.0
CMS2_k127_459795_10 BON domain K04065 - - 0.00000000000000000000000000004536 123.0
CMS2_k127_459795_11 - - - - 0.000000000000000000000000000275 122.0
CMS2_k127_459795_12 to GP 6723233 - - - 0.0000000000000000009163 93.0
CMS2_k127_459795_13 UPF0391 membrane protein - - - 0.000000000000003177 76.0
CMS2_k127_459795_14 Las17-binding protein actin regulator - - - 0.00000000008205 72.0
CMS2_k127_459795_15 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000003293 58.0
CMS2_k127_459795_2 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002142 289.0
CMS2_k127_459795_3 Bacterioferritin (cytochrome b1) K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000004465 249.0
CMS2_k127_459795_4 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000005796 223.0
CMS2_k127_459795_5 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000004011 205.0
CMS2_k127_459795_6 hmm pf02371 - - - 0.0000000000000000000000000000000000000000000000000001041 193.0
CMS2_k127_459795_7 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000000000000000003588 154.0
CMS2_k127_459795_8 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000002951 143.0
CMS2_k127_459795_9 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000005372 144.0
CMS2_k127_4607197_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1432.0
CMS2_k127_4607197_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1210.0
CMS2_k127_4607197_10 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 445.0
CMS2_k127_4607197_11 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 417.0
CMS2_k127_4607197_12 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 422.0
CMS2_k127_4607197_13 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 395.0
CMS2_k127_4607197_14 COG0500 SAM-dependent methyltransferases K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 380.0
CMS2_k127_4607197_15 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 382.0
CMS2_k127_4607197_16 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 375.0
CMS2_k127_4607197_17 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 361.0
CMS2_k127_4607197_18 Histidine kinase internal region K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 359.0
CMS2_k127_4607197_19 Lysine methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 334.0
CMS2_k127_4607197_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 2.078e-240 751.0
CMS2_k127_4607197_20 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 337.0
CMS2_k127_4607197_21 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 340.0
CMS2_k127_4607197_22 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 347.0
CMS2_k127_4607197_23 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 325.0
CMS2_k127_4607197_24 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 322.0
CMS2_k127_4607197_25 Flavin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 313.0
CMS2_k127_4607197_26 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 304.0
CMS2_k127_4607197_27 PFAM response regulator receiver K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 319.0
CMS2_k127_4607197_28 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 324.0
CMS2_k127_4607197_29 PFAM Mg2 transporter protein, CorA family protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 299.0
CMS2_k127_4607197_3 argininosuccinate lyase K01755 - 4.3.2.1 2.563e-235 737.0
CMS2_k127_4607197_30 Amino acid synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 286.0
CMS2_k127_4607197_31 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001003 278.0
CMS2_k127_4607197_32 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003137 278.0
CMS2_k127_4607197_33 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003206 284.0
CMS2_k127_4607197_34 KDPG and KHG aldolase K01631 - 4.1.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000001888 265.0
CMS2_k127_4607197_35 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000007128 265.0
CMS2_k127_4607197_36 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008235 261.0
CMS2_k127_4607197_37 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006329 243.0
CMS2_k127_4607197_38 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000003622 239.0
CMS2_k127_4607197_39 Hydratase decarboxylase family protein 1 - - - 0.000000000000000000000000000000000000000000000000000000002963 204.0
CMS2_k127_4607197_4 von Willebrand factor (vWF) type A domain K02448 - - 2.196e-225 718.0
CMS2_k127_4607197_40 Transcriptional regulator K03892 - - 0.00000000000000000000000000000000000000000000000636 173.0
CMS2_k127_4607197_41 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000005248 181.0
CMS2_k127_4607197_42 Glutaredoxin - - - 0.000000000000000000000000000000000000000000001837 172.0
CMS2_k127_4607197_43 DoxX K15977 - - 0.00000000000000000000000000000000000000000001588 166.0
CMS2_k127_4607197_44 RNA-binding protein - - - 0.00000000000000000000000000000000000000009625 153.0
CMS2_k127_4607197_45 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000001353 142.0
CMS2_k127_4607197_46 ethyl tert-butyl ether degradation - - - 0.00000000000000000000000000000000003322 136.0
CMS2_k127_4607197_47 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000007026 136.0
CMS2_k127_4607197_48 Cold shock protein K03704 - - 0.00000000000000000000000000000002473 137.0
CMS2_k127_4607197_49 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000004226 118.0
CMS2_k127_4607197_5 phosphorelay signal transduction system K12132 - 2.7.11.1 3.319e-202 646.0
CMS2_k127_4607197_51 Domain of unknown function (DUF4437) - - - 0.000000000001126 72.0
CMS2_k127_4607197_52 cellulose binding - - - 0.00000000002937 77.0
CMS2_k127_4607197_53 Protein of unknown function (DUF3025) - - - 0.0000001507 62.0
CMS2_k127_4607197_55 Putative transposase - - - 0.00001921 53.0
CMS2_k127_4607197_6 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 621.0
CMS2_k127_4607197_7 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 601.0
CMS2_k127_4607197_8 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 600.0
CMS2_k127_4607197_9 Benzoate membrane transport protein K05782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 514.0
CMS2_k127_4615203_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1167.0
CMS2_k127_4615203_1 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 3.535e-300 941.0
CMS2_k127_4615203_10 Bacterial extracellular solute-binding protein K10236 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 596.0
CMS2_k127_4615203_11 Protein of unknown function (DUF1214) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 591.0
CMS2_k127_4615203_12 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 570.0
CMS2_k127_4615203_13 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 558.0
CMS2_k127_4615203_14 Permease, YjgP YjgQ K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 512.0
CMS2_k127_4615203_15 Transcriptional regulator, LysR family K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 492.0
CMS2_k127_4615203_16 Permease, YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 501.0
CMS2_k127_4615203_17 PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 482.0
CMS2_k127_4615203_18 Belongs to the ABC transporter superfamily K10111 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 467.0
CMS2_k127_4615203_19 COG1175 ABC-type sugar transport systems permease components K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 443.0
CMS2_k127_4615203_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.475e-229 715.0
CMS2_k127_4615203_20 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 428.0
CMS2_k127_4615203_21 Lipoprotein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009279,GO:0010033,GO:0010243,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031240,GO:0031975,GO:0042221,GO:0044424,GO:0044425,GO:0044444,GO:0044462,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:1901652,GO:1901698,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 404.0
CMS2_k127_4615203_22 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 404.0
CMS2_k127_4615203_23 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 382.0
CMS2_k127_4615203_24 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 373.0
CMS2_k127_4615203_25 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 342.0
CMS2_k127_4615203_26 MltA-interacting protein MipA K07274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 297.0
CMS2_k127_4615203_27 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 287.0
CMS2_k127_4615203_28 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 288.0
CMS2_k127_4615203_29 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 289.0
CMS2_k127_4615203_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.989e-227 713.0
CMS2_k127_4615203_30 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008022 278.0
CMS2_k127_4615203_31 PFAM MscS Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009861 307.0
CMS2_k127_4615203_32 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000002163 247.0
CMS2_k127_4615203_33 - - - - 0.0000000000000000000000000000000000000000000000000392 189.0
CMS2_k127_4615203_34 - - - - 0.0000000000000000000000000000000000000000000000003317 185.0
CMS2_k127_4615203_35 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000817 184.0
CMS2_k127_4615203_36 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000113 181.0
CMS2_k127_4615203_37 Nitrile hydratase beta subunit - - - 0.00000000000000000000000000000000000000000000331 171.0
CMS2_k127_4615203_38 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000001353 154.0
CMS2_k127_4615203_39 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000003386 145.0
CMS2_k127_4615203_4 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 3.847e-219 692.0
CMS2_k127_4615203_40 CbiX K03795 - 4.99.1.3 0.00000000000000000000000000000008902 131.0
CMS2_k127_4615203_41 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000001809 109.0
CMS2_k127_4615203_42 - - - - 0.000000000000000000000001389 112.0
CMS2_k127_4615203_43 - - - - 0.00000000000000000000955 96.0
CMS2_k127_4615203_45 - - - - 0.000000000000000004703 92.0
CMS2_k127_4615203_46 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000003953 83.0
CMS2_k127_4615203_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 1.853e-208 658.0
CMS2_k127_4615203_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.106e-200 642.0
CMS2_k127_4615203_7 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 3.473e-199 628.0
CMS2_k127_4615203_8 PFAM Aminotransferase class I and II K14287 - 2.6.1.88 1.285e-196 625.0
CMS2_k127_4615203_9 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 595.0
CMS2_k127_4648533_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0 1161.0
CMS2_k127_4648533_1 Cation transporter/ATPase, N-terminus K01531,K01535 - 3.6.3.2,3.6.3.6 2.528e-296 931.0
CMS2_k127_4648533_10 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 600.0
CMS2_k127_4648533_11 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 592.0
CMS2_k127_4648533_12 Proline racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 553.0
CMS2_k127_4648533_13 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K21624 GO:0000287,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0016597,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0031406,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043200,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046872,GO:0050896,GO:0051716,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:1901564,GO:1901605,GO:1901698,GO:1901699,GO:1901700,GO:1901701 4.2.1.171 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 546.0
CMS2_k127_4648533_14 Belongs to the arginase family K01480,K12255 - 3.5.3.11,3.5.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 503.0
CMS2_k127_4648533_15 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 502.0
CMS2_k127_4648533_16 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 498.0
CMS2_k127_4648533_17 transport system permease K11075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 484.0
CMS2_k127_4648533_18 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 444.0
CMS2_k127_4648533_19 Belongs to the DapA family K21062 - 3.5.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 439.0
CMS2_k127_4648533_2 glutamine synthetase K01915 - 6.3.1.2 9.841e-270 837.0
CMS2_k127_4648533_20 Belongs to the proline racemase family K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 429.0
CMS2_k127_4648533_21 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772,K03815 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 431.0
CMS2_k127_4648533_22 transport system permease K11074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 432.0
CMS2_k127_4648533_23 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 415.0
CMS2_k127_4648533_24 PFAM ABC transporter related K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 405.0
CMS2_k127_4648533_25 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 351.0
CMS2_k127_4648533_26 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 368.0
CMS2_k127_4648533_27 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 319.0
CMS2_k127_4648533_28 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 300.0
CMS2_k127_4648533_29 ABC-type amino acid transport system, permease component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001118 268.0
CMS2_k127_4648533_3 belongs to the aldehyde dehydrogenase family K00130,K09472,K12254 - 1.2.1.54,1.2.1.8,1.2.1.99 9.847e-256 795.0
CMS2_k127_4648533_30 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000173 258.0
CMS2_k127_4648533_31 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003181 242.0
CMS2_k127_4648533_32 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000004058 236.0
CMS2_k127_4648533_33 FCD - - - 0.0000000000000000000000000000000000000000000000000000002385 210.0
CMS2_k127_4648533_34 Protein of unknown function (DUF504) - - - 0.00000000000000000000007406 101.0
CMS2_k127_4648533_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 7.094e-246 764.0
CMS2_k127_4648533_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 2.011e-245 788.0
CMS2_k127_4648533_6 NADPH-dependent glutamate synthase beta - - - 1.289e-209 655.0
CMS2_k127_4648533_7 glutamine synthetase K01915 - 6.3.1.2 2.272e-203 664.0
CMS2_k127_4648533_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 6.264e-198 622.0
CMS2_k127_4648533_9 FAD dependent oxidoreductase K09471 - - 6.101e-194 638.0
CMS2_k127_4729546_0 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.0 1265.0
CMS2_k127_4729546_1 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 0.0 1158.0
CMS2_k127_4729546_10 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 613.0
CMS2_k127_4729546_11 C-terminal region of band_7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 497.0
CMS2_k127_4729546_12 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 477.0
CMS2_k127_4729546_13 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 456.0
CMS2_k127_4729546_14 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 427.0
CMS2_k127_4729546_15 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 410.0
CMS2_k127_4729546_16 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 408.0
CMS2_k127_4729546_17 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 384.0
CMS2_k127_4729546_18 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 356.0
CMS2_k127_4729546_19 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 335.0
CMS2_k127_4729546_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1109.0
CMS2_k127_4729546_20 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 292.0
CMS2_k127_4729546_21 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006502 249.0
CMS2_k127_4729546_22 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000000000000001168 213.0
CMS2_k127_4729546_23 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000006062 203.0
CMS2_k127_4729546_24 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000000000000000000000000007966 199.0
CMS2_k127_4729546_25 heat shock protein DnaJ K05516 - - 0.000000000000000000000000000000000000000000000000000001365 198.0
CMS2_k127_4729546_26 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.000000000000000000000000000000000000000000000000009673 196.0
CMS2_k127_4729546_27 phosphoribosyl transferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000524 174.0
CMS2_k127_4729546_28 - - - - 0.000000000000000000000000004653 113.0
CMS2_k127_4729546_29 Dodecin K09165 - - 0.00000000000000000000003997 103.0
CMS2_k127_4729546_3 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1047.0
CMS2_k127_4729546_4 GTP-binding protein K06207 - - 0.0 1015.0
CMS2_k127_4729546_5 Heat shock 70 kDa protein K04043 - - 4.279e-274 855.0
CMS2_k127_4729546_6 DNA polymerase X family K02347 - - 6.404e-264 830.0
CMS2_k127_4729546_7 Participates in both transcription termination and antitermination K02600 - - 1.104e-263 830.0
CMS2_k127_4729546_8 PFAM AMP-dependent synthetase and ligase K00666 - - 9.95e-263 841.0
CMS2_k127_4729546_9 FAD binding domain - - - 4.611e-197 623.0
CMS2_k127_474270_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 4.794e-270 838.0
CMS2_k127_474270_1 polyphosphate kinase K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 604.0
CMS2_k127_474270_2 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 532.0
CMS2_k127_474270_3 Belongs to the IlvD Edd family K22186 - 4.2.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 444.0
CMS2_k127_474270_4 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 445.0
CMS2_k127_474270_5 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 360.0
CMS2_k127_474270_6 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 362.0
CMS2_k127_474270_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 351.0
CMS2_k127_474270_8 - - - - 0.000000000000000000000000000000000000000000000000000000001475 213.0
CMS2_k127_477052_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1056.0
CMS2_k127_477052_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.46e-261 809.0
CMS2_k127_477052_10 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000005922 234.0
CMS2_k127_477052_11 TIGRFAM Succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.000000000000000000000000000000000000000000000000000000000005947 211.0
CMS2_k127_477052_12 FCD - - - 0.000000000000000000000000000000000000000000000000000000001963 205.0
CMS2_k127_477052_13 Succinate dehydrogenase cytochrome b556 subunit K00241 - - 0.000000000000000000000000000000000000000000000000000368 188.0
CMS2_k127_477052_14 Signal peptide protein - - - 0.0000000000000000000000000000000000000000000001553 175.0
CMS2_k127_477052_15 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000000000000000009164 121.0
CMS2_k127_477052_16 - - - - 0.000000000002257 75.0
CMS2_k127_477052_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 583.0
CMS2_k127_477052_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 561.0
CMS2_k127_477052_4 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 541.0
CMS2_k127_477052_5 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 469.0
CMS2_k127_477052_6 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 448.0
CMS2_k127_477052_7 Transcriptional regulator, GntR family K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 377.0
CMS2_k127_477052_8 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 370.0
CMS2_k127_477052_9 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 337.0
CMS2_k127_4860379_0 Elongation factor G, domain IV K02355 - - 0.0 1097.0
CMS2_k127_4860379_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 7.613e-255 795.0
CMS2_k127_4860379_10 - - - - 0.00000000000000000000000000000000000000001897 162.0
CMS2_k127_4860379_12 COG NOG14600 non supervised orthologous group - - - 0.0001847 45.0
CMS2_k127_4860379_2 GMC oxidoreductase - - - 2.48e-244 765.0
CMS2_k127_4860379_3 Aldo keto K00011 - 1.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 368.0
CMS2_k127_4860379_4 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 356.0
CMS2_k127_4860379_5 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001354 287.0
CMS2_k127_4860379_6 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003357 244.0
CMS2_k127_4860379_7 Dienelactone hydrolase family K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000143 239.0
CMS2_k127_4860379_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006025 240.0
CMS2_k127_4860379_9 - - - - 0.0000000000000000000000000000000000000000005834 157.0
CMS2_k127_5035634_0 FtsX-like permease family K02004 - - 0.0 1180.0
CMS2_k127_5035634_1 FtsX-like permease family K02004 - - 0.0 1168.0
CMS2_k127_5035634_10 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 3.28e-264 831.0
CMS2_k127_5035634_100 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.00001207 49.0
CMS2_k127_5035634_101 - - - - 0.0006441 47.0
CMS2_k127_5035634_11 ABC transporter K02056 - 3.6.3.17 1.141e-259 810.0
CMS2_k127_5035634_12 mandelate racemase muconate lactonizing K01706 - 4.2.1.40 2.067e-254 788.0
CMS2_k127_5035634_13 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.057e-245 767.0
CMS2_k127_5035634_14 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 3.872e-233 731.0
CMS2_k127_5035634_15 TRAP C4-dicarboxylate transport system permease DctM subunit K11690,K21393 - - 1.647e-224 701.0
CMS2_k127_5035634_16 helicase superfamily c-terminal domain K03724 - - 2.043e-223 702.0
CMS2_k127_5035634_17 binding-protein-dependent transport systems inner membrane component K02011 - - 7.856e-222 711.0
CMS2_k127_5035634_18 Peptidase family M48 - - - 4.015e-216 681.0
CMS2_k127_5035634_19 CO dehydrogenase flavoprotein domain protein K13481 - 1.17.1.4 4.498e-210 664.0
CMS2_k127_5035634_2 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K13482 - 1.17.1.4 0.0 1136.0
CMS2_k127_5035634_20 basic membrane K02058 - - 1.134e-208 653.0
CMS2_k127_5035634_21 Histidine kinase K07673 - 2.7.13.3 4.357e-203 649.0
CMS2_k127_5035634_22 Guanine deaminase K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 609.0
CMS2_k127_5035634_23 Sodium/hydrogen exchanger family K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 587.0
CMS2_k127_5035634_24 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 570.0
CMS2_k127_5035634_25 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 565.0
CMS2_k127_5035634_26 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 563.0
CMS2_k127_5035634_27 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 569.0
CMS2_k127_5035634_28 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 561.0
CMS2_k127_5035634_29 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 559.0
CMS2_k127_5035634_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0 1058.0
CMS2_k127_5035634_30 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 564.0
CMS2_k127_5035634_31 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 557.0
CMS2_k127_5035634_32 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 546.0
CMS2_k127_5035634_33 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 552.0
CMS2_k127_5035634_34 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 518.0
CMS2_k127_5035634_35 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 514.0
CMS2_k127_5035634_36 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 495.0
CMS2_k127_5035634_37 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 528.0
CMS2_k127_5035634_38 PFAM SMP-30 Gluconolaconase K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 503.0
CMS2_k127_5035634_39 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 485.0
CMS2_k127_5035634_4 ABC transporter K06020 - 3.6.3.25 1.364e-321 990.0
CMS2_k127_5035634_40 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 482.0
CMS2_k127_5035634_41 PFAM aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 469.0
CMS2_k127_5035634_42 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 453.0
CMS2_k127_5035634_43 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 456.0
CMS2_k127_5035634_44 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 459.0
CMS2_k127_5035634_45 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 454.0
CMS2_k127_5035634_46 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 446.0
CMS2_k127_5035634_47 NAD-dependent epimerase dehydratase K18981 - 1.1.1.203 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 434.0
CMS2_k127_5035634_48 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 449.0
CMS2_k127_5035634_49 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 434.0
CMS2_k127_5035634_5 PFAM Major Facilitator Superfamily K02575 - - 1.621e-313 986.0
CMS2_k127_5035634_50 helicase superfamily c-terminal domain K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 432.0
CMS2_k127_5035634_51 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 430.0
CMS2_k127_5035634_52 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 426.0
CMS2_k127_5035634_53 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 421.0
CMS2_k127_5035634_54 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 419.0
CMS2_k127_5035634_55 Bacterial regulatory helix-turn-helix protein, lysR family K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 415.0
CMS2_k127_5035634_56 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 408.0
CMS2_k127_5035634_57 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 413.0
CMS2_k127_5035634_58 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 392.0
CMS2_k127_5035634_59 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 387.0
CMS2_k127_5035634_6 Domain of unknown function (DUF5117) - - - 2.561e-310 975.0
CMS2_k127_5035634_60 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 382.0
CMS2_k127_5035634_61 Carboxylesterase family K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 383.0
CMS2_k127_5035634_62 Nitrate reductase K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 379.0
CMS2_k127_5035634_63 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 377.0
CMS2_k127_5035634_64 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 361.0
CMS2_k127_5035634_65 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 356.0
CMS2_k127_5035634_66 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 376.0
CMS2_k127_5035634_67 Extradiol ring-cleavage dioxygenase, class III K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 330.0
CMS2_k127_5035634_68 TIGRFAM molybdate ABC transporter K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 338.0
CMS2_k127_5035634_69 citrate synthase K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 320.0
CMS2_k127_5035634_7 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 3.884e-289 890.0
CMS2_k127_5035634_70 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 310.0
CMS2_k127_5035634_71 TIGRFAM xanthine dehydrogenase accessory protein XdhC K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 311.0
CMS2_k127_5035634_72 Polycystin cation channel K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 305.0
CMS2_k127_5035634_73 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 315.0
CMS2_k127_5035634_74 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 299.0
CMS2_k127_5035634_75 AAA domain, putative AbiEii toxin, Type IV TA system K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 293.0
CMS2_k127_5035634_76 peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 299.0
CMS2_k127_5035634_77 PFAM binding-protein-dependent transport systems inner membrane component K05773,K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001202 286.0
CMS2_k127_5035634_78 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003288 291.0
CMS2_k127_5035634_79 Nitrate reductase delta subunit K00373 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006168 288.0
CMS2_k127_5035634_8 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 2.862e-277 863.0
CMS2_k127_5035634_80 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001177 274.0
CMS2_k127_5035634_81 Tripartite ATP-independent periplasmic transporter, DctQ K21394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001994 267.0
CMS2_k127_5035634_82 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006746 258.0
CMS2_k127_5035634_83 Bacterial regulatory proteins, luxR family K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000003299 250.0
CMS2_k127_5035634_84 - - - - 0.000000000000000000000000000000000000000000000000000000000000001021 224.0
CMS2_k127_5035634_85 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000353 235.0
CMS2_k127_5035634_86 membrane - - - 0.00000000000000000000000000000000000000000000000000002055 191.0
CMS2_k127_5035634_87 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000232 189.0
CMS2_k127_5035634_88 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000000000000000000000000000000001428 188.0
CMS2_k127_5035634_89 Staphylococcal nuclease homologue - - - 0.0000000000000000000000000000000000000000001356 175.0
CMS2_k127_5035634_9 Cysteine-rich domain - - - 1.049e-267 829.0
CMS2_k127_5035634_90 Hemerythrin HHE cation binding domain protein - - - 0.000000000000000000000000000000000000000000799 163.0
CMS2_k127_5035634_91 GYD domain - - - 0.000000000000000000000000000000000003763 141.0
CMS2_k127_5035634_92 - - - - 0.00000000000000000000000000000000002163 141.0
CMS2_k127_5035634_93 Putative heavy-metal chelation - - - 0.00000000000000000000000000000003561 126.0
CMS2_k127_5035634_94 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000005118 134.0
CMS2_k127_5035634_95 - - - - 0.000000000000000000000000009869 113.0
CMS2_k127_5035634_96 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.00000000000000000000008889 100.0
CMS2_k127_5035634_97 NADPH-dependent FMN reductase - - - 0.00000000000000000001047 105.0
CMS2_k127_5035634_98 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000001275 70.0
CMS2_k127_5035634_99 SnoaL-like domain - - - 0.0000000005322 67.0
CMS2_k127_5097743_0 Monomeric isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1315.0
CMS2_k127_5097743_1 FtsX-like permease family K02004 - - 2.914e-289 912.0
CMS2_k127_5097743_10 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 461.0
CMS2_k127_5097743_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 428.0
CMS2_k127_5097743_12 Major Facilitator Superfamily K07552,K18552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 412.0
CMS2_k127_5097743_13 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 412.0
CMS2_k127_5097743_14 CYTH K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 372.0
CMS2_k127_5097743_15 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 378.0
CMS2_k127_5097743_16 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 319.0
CMS2_k127_5097743_17 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 294.0
CMS2_k127_5097743_18 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 298.0
CMS2_k127_5097743_19 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007211 292.0
CMS2_k127_5097743_2 Proton-conducting membrane transporter K12141 - - 2.627e-259 805.0
CMS2_k127_5097743_20 (Lipo)protein - - - 0.00000000000000000000000000000000000000000000001274 177.0
CMS2_k127_5097743_21 - - - - 0.0000000000000000000000000004615 121.0
CMS2_k127_5097743_22 Response regulators consisting of a CheY-like receiver domain and a - - - 0.000000000000000000000000001203 115.0
CMS2_k127_5097743_23 Protein of unknown function (DUF3460) - - - 0.000000000000000000000002671 104.0
CMS2_k127_5097743_24 Protein of unknown function, DUF599 - - - 0.0000000001445 65.0
CMS2_k127_5097743_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 7.942e-232 727.0
CMS2_k127_5097743_4 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 609.0
CMS2_k127_5097743_5 Oxidoreductase K10219 - 1.1.1.312 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 567.0
CMS2_k127_5097743_6 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 554.0
CMS2_k127_5097743_7 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 540.0
CMS2_k127_5097743_8 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 500.0
CMS2_k127_5097743_9 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 459.0
CMS2_k127_5159306_0 PFAM Dehydrogenase, E1 component K00166 - 1.2.4.4 2.066e-225 702.0
CMS2_k127_5159306_1 Transketolase, C-terminal domain K00167 - 1.2.4.4 4.248e-201 630.0
CMS2_k127_5159306_2 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes K09699 - 2.3.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 496.0
CMS2_k127_5159306_3 - - - - 0.0000000000001562 77.0
CMS2_k127_5183958_0 glutamate synthase, alpha subunit domain protein K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2010.0
CMS2_k127_5183958_1 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0 1114.0
CMS2_k127_5183958_10 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004331 254.0
CMS2_k127_5183958_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000002521 249.0
CMS2_k127_5183958_12 pilus assembly protein PilP K02665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000249 246.0
CMS2_k127_5183958_13 Belongs to the frataxin family K06202 - - 0.000000000000000000000000000000000000005102 148.0
CMS2_k127_5183958_2 type II and III secretion system protein K02666 - - 1.347e-307 957.0
CMS2_k127_5183958_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 8.408e-208 658.0
CMS2_k127_5183958_4 pilus assembly protein PilM K02662 - - 6.985e-201 629.0
CMS2_k127_5183958_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 503.0
CMS2_k127_5183958_6 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 486.0
CMS2_k127_5183958_7 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 423.0
CMS2_k127_5183958_8 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 317.0
CMS2_k127_5183958_9 Fimbrial assembly K02663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001036 256.0
CMS2_k127_5276615_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1204.0
CMS2_k127_5276615_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1173.0
CMS2_k127_5276615_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 577.0
CMS2_k127_5276615_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 529.0
CMS2_k127_5276615_12 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 511.0
CMS2_k127_5276615_13 3-beta hydroxysteroid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 497.0
CMS2_k127_5276615_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 486.0
CMS2_k127_5276615_15 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 447.0
CMS2_k127_5276615_16 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 470.0
CMS2_k127_5276615_17 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 428.0
CMS2_k127_5276615_18 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 409.0
CMS2_k127_5276615_19 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 397.0
CMS2_k127_5276615_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.053e-316 974.0
CMS2_k127_5276615_20 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 349.0
CMS2_k127_5276615_21 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 358.0
CMS2_k127_5276615_22 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 334.0
CMS2_k127_5276615_23 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 297.0
CMS2_k127_5276615_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000484 276.0
CMS2_k127_5276615_25 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000001844 237.0
CMS2_k127_5276615_26 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000001225 223.0
CMS2_k127_5276615_27 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000008644 218.0
CMS2_k127_5276615_28 - - - - 0.0000000000000000000000000000000000000000000000000000000006202 208.0
CMS2_k127_5276615_29 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000000000000000000000000001536 201.0
CMS2_k127_5276615_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 4.796e-295 917.0
CMS2_k127_5276615_30 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000001932 185.0
CMS2_k127_5276615_31 PFAM Cytochrome c, class I K08738 - - 0.0000000000000000000000000000000000000001185 152.0
CMS2_k127_5276615_32 Staphylococcal nuclease homologues - - - 0.00000000000000000000000000000006825 126.0
CMS2_k127_5276615_33 Universal stress protein family - - - 0.0000000000000000000000000001097 121.0
CMS2_k127_5276615_34 Phosphopantetheine attachment site - - - 0.0000000000000000000002384 100.0
CMS2_k127_5276615_35 - - - - 0.000000000000000000001282 97.0
CMS2_k127_5276615_36 Sulfite exporter TauE/SafE K07090 - - 0.00000000000005654 72.0
CMS2_k127_5276615_4 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 5.673e-293 923.0
CMS2_k127_5276615_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.02e-254 792.0
CMS2_k127_5276615_6 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 585.0
CMS2_k127_5276615_7 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 595.0
CMS2_k127_5276615_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 582.0
CMS2_k127_5276615_9 NADH flavin oxidoreductase NADH oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 558.0
CMS2_k127_5321767_0 Acetamidase/Formamidase family K01455 - 3.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 558.0
CMS2_k127_5321767_1 - - - - 0.0000000000000000000000000000000000001233 151.0
CMS2_k127_5341203_0 PFAM amidohydrolase K01464,K01466 - 3.5.2.2,3.5.2.5 3.227e-278 870.0
CMS2_k127_5341203_1 iron ion homeostasis - - - 1.434e-249 791.0
CMS2_k127_5341203_10 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 379.0
CMS2_k127_5341203_11 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 339.0
CMS2_k127_5341203_12 PFAM ABC transporter related K01995,K10822 - 3.6.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 351.0
CMS2_k127_5341203_13 Branched-chain amino acid transport K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 340.0
CMS2_k127_5341203_14 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003167 277.0
CMS2_k127_5341203_15 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002398 266.0
CMS2_k127_5341203_16 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000001362 224.0
CMS2_k127_5341203_17 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000001302 189.0
CMS2_k127_5341203_18 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000000001735 156.0
CMS2_k127_5341203_19 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000007102 133.0
CMS2_k127_5341203_2 Extracellular liganD-binding receptor K01999 - - 1.002e-209 663.0
CMS2_k127_5341203_20 - - - - 0.0000000000000000000000000000000001971 135.0
CMS2_k127_5341203_21 - - - - 0.00000000000000000000000000001154 123.0
CMS2_k127_5341203_22 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000001156 121.0
CMS2_k127_5341203_23 Glycine zipper 2TM domain K04062 - - 0.00000000000000000001195 98.0
CMS2_k127_5341203_24 - - - - 0.00000000000000001892 83.0
CMS2_k127_5341203_25 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000235 69.0
CMS2_k127_5341203_3 3-isopropylmalate dehydratase large subunit K01703 - 4.2.1.33,4.2.1.35 6.794e-197 634.0
CMS2_k127_5341203_4 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 572.0
CMS2_k127_5341203_5 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 503.0
CMS2_k127_5341203_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 466.0
CMS2_k127_5341203_7 Beta/gamma crystallins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 459.0
CMS2_k127_5341203_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 457.0
CMS2_k127_5341203_9 Phosphoenolpyruvate phosphomutase K01841,K03417 - 4.1.3.30,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 428.0
CMS2_k127_5390330_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1517.0
CMS2_k127_5390330_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1376.0
CMS2_k127_5390330_10 MgsA AAA+ ATPase C terminal K07478 - - 2.035e-210 662.0
CMS2_k127_5390330_11 PFAM fatty acid desaturase K00507 - 1.14.19.1 1.208e-205 645.0
CMS2_k127_5390330_12 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 605.0
CMS2_k127_5390330_13 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 599.0
CMS2_k127_5390330_14 CoA-transferase family III K18289 - 2.8.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 586.0
CMS2_k127_5390330_15 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 571.0
CMS2_k127_5390330_16 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 577.0
CMS2_k127_5390330_17 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 572.0
CMS2_k127_5390330_18 oxidoreductase FAD NAD(P)-binding domain protein K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 561.0
CMS2_k127_5390330_19 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 558.0
CMS2_k127_5390330_2 His Kinase A (phosphoacceptor) domain - - - 0.0 1350.0
CMS2_k127_5390330_20 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 553.0
CMS2_k127_5390330_21 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 544.0
CMS2_k127_5390330_22 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 541.0
CMS2_k127_5390330_23 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 533.0
CMS2_k127_5390330_24 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 529.0
CMS2_k127_5390330_25 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 518.0
CMS2_k127_5390330_26 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 513.0
CMS2_k127_5390330_27 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 502.0
CMS2_k127_5390330_28 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 488.0
CMS2_k127_5390330_29 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 461.0
CMS2_k127_5390330_3 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0 1288.0
CMS2_k127_5390330_30 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 460.0
CMS2_k127_5390330_31 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 435.0
CMS2_k127_5390330_32 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 410.0
CMS2_k127_5390330_33 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 407.0
CMS2_k127_5390330_34 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 400.0
CMS2_k127_5390330_35 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 391.0
CMS2_k127_5390330_36 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 389.0
CMS2_k127_5390330_37 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 394.0
CMS2_k127_5390330_38 Transcriptional regulator, Crp Fnr family K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 366.0
CMS2_k127_5390330_39 PAC sensor-containing diguanylate cyclase phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 369.0
CMS2_k127_5390330_4 Ftsk_gamma K03466 - - 0.0 1163.0
CMS2_k127_5390330_40 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 368.0
CMS2_k127_5390330_41 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 349.0
CMS2_k127_5390330_42 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 337.0
CMS2_k127_5390330_43 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 330.0
CMS2_k127_5390330_44 Eukaryotic integral membrane protein (DUF1751) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 302.0
CMS2_k127_5390330_45 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 293.0
CMS2_k127_5390330_46 AmiS/UreI family transporter K03191,K22112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 291.0
CMS2_k127_5390330_47 Nudix N-terminal K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005374 278.0
CMS2_k127_5390330_48 Protein of unknown function (DUF3717) K06938 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002239 263.0
CMS2_k127_5390330_49 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003924 255.0
CMS2_k127_5390330_5 Acetamidase/Formamidase family K01455 - 3.5.1.49 2.767e-267 824.0
CMS2_k127_5390330_50 transporter K11021,K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000007774 228.0
CMS2_k127_5390330_51 - - - - 0.0000000000000000000000000000000000000000000000000000000000001612 228.0
CMS2_k127_5390330_52 HemY domain protein - - - 0.00000000000000000000000000000000000000000000000000000003995 217.0
CMS2_k127_5390330_53 Uncharacterized protein conserved in bacteria (DUF2242) - - - 0.0000000000000000000000000000000000000000000000004427 186.0
CMS2_k127_5390330_54 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000622 172.0
CMS2_k127_5390330_55 Heavy-metal resistance - - - 0.0000000000000000000000000000000000000000002539 169.0
CMS2_k127_5390330_56 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000002411 145.0
CMS2_k127_5390330_57 Belongs to the ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000007287 149.0
CMS2_k127_5390330_58 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000002367 148.0
CMS2_k127_5390330_59 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000004183 129.0
CMS2_k127_5390330_6 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 6.201e-255 791.0
CMS2_k127_5390330_60 Putative regulatory protein - - - 0.0000000000000000000000000000009789 126.0
CMS2_k127_5390330_61 Putative regulatory protein - - - 0.000000000000000000000000008232 111.0
CMS2_k127_5390330_62 - - - - 0.00000000000000000000000003202 111.0
CMS2_k127_5390330_63 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000003454 106.0
CMS2_k127_5390330_64 - - - - 0.00000000000000000000002198 113.0
CMS2_k127_5390330_65 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000002689 98.0
CMS2_k127_5390330_66 protein secretion K20276 - - 0.00000000000000005644 95.0
CMS2_k127_5390330_67 STAS domain - - - 0.0000000000000000761 86.0
CMS2_k127_5390330_68 - - - - 0.0000000000000003441 82.0
CMS2_k127_5390330_69 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000003106 59.0
CMS2_k127_5390330_7 Ammonium Transporter K03320,K06580 - - 3.258e-221 694.0
CMS2_k127_5390330_8 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 3.176e-214 668.0
CMS2_k127_5390330_9 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 1.087e-213 669.0
CMS2_k127_5461164_0 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 495.0
CMS2_k127_5461164_1 Alpha beta hydrolase K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 468.0
CMS2_k127_5461164_10 Ankyrin repeats (many copies) K06867 - - 0.00000000000000000000000000000000000000000000000000000001191 204.0
CMS2_k127_5461164_11 - - - - 0.000000000000006966 80.0
CMS2_k127_5461164_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 460.0
CMS2_k127_5461164_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 396.0
CMS2_k127_5461164_4 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 384.0
CMS2_k127_5461164_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 366.0
CMS2_k127_5461164_6 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 368.0
CMS2_k127_5461164_7 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 355.0
CMS2_k127_5461164_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003073 275.0
CMS2_k127_5461164_9 pilus assembly K02676 - - 0.0000000000000000000000000000000000000000000000000000000000008964 211.0
CMS2_k127_5531303_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 566.0
CMS2_k127_5531303_1 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 501.0
CMS2_k127_5531303_2 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 319.0
CMS2_k127_5531303_3 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000005731 243.0
CMS2_k127_5531303_4 - - - - 0.000000000000000000000000000000000000000000000000000000232 203.0
CMS2_k127_5531303_5 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000001008 197.0
CMS2_k127_5531303_6 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000537 107.0
CMS2_k127_553516_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1644.0
CMS2_k127_553516_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1056.0
CMS2_k127_553516_10 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 339.0
CMS2_k127_553516_11 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 324.0
CMS2_k127_553516_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 304.0
CMS2_k127_553516_13 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 293.0
CMS2_k127_553516_14 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 293.0
CMS2_k127_553516_15 Complex I intermediate-associated protein 30 (CIA30) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008364 257.0
CMS2_k127_553516_16 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000874 254.0
CMS2_k127_553516_17 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000001462 235.0
CMS2_k127_553516_18 Cytochrome c - - - 0.00000000000000000000000000000005663 132.0
CMS2_k127_553516_19 Helix-turn-helix domain protein - - - 0.0000000000000000000000000003377 120.0
CMS2_k127_553516_2 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 1.67e-278 872.0
CMS2_k127_553516_20 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000003426 112.0
CMS2_k127_553516_21 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000008322 71.0
CMS2_k127_553516_22 Putative transposase - - - 0.00004626 46.0
CMS2_k127_553516_23 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0001966 51.0
CMS2_k127_553516_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 1.099e-238 751.0
CMS2_k127_553516_4 Belongs to the UPF0061 (SELO) family - - - 6.585e-219 695.0
CMS2_k127_553516_5 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 555.0
CMS2_k127_553516_6 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 547.0
CMS2_k127_553516_7 cell septum assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 463.0
CMS2_k127_553516_8 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 367.0
CMS2_k127_553516_9 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 344.0
CMS2_k127_5661324_0 pfkB family carbohydrate kinase K03338 - 2.7.1.92 6.735e-291 924.0
CMS2_k127_5661324_1 ABC transporter, transmembrane region K06147 - - 4.531e-281 876.0
CMS2_k127_5661324_10 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 318.0
CMS2_k127_5661324_11 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008501 281.0
CMS2_k127_5661324_12 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002442 248.0
CMS2_k127_5661324_13 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000009165 215.0
CMS2_k127_5661324_14 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000202 211.0
CMS2_k127_5661324_15 transcriptional regulator, Rrf2 family K13771 - - 0.0000000000000000000000000000000000000000004963 164.0
CMS2_k127_5661324_16 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000002166 130.0
CMS2_k127_5661324_17 Uncharacterized conserved protein (DUF2249) K07322 - - 0.00000000000000000000000000000002619 137.0
CMS2_k127_5661324_18 Hemerythrin HHE cation binding domain - - - 0.00000000000000005347 88.0
CMS2_k127_5661324_2 Belongs to the TPP enzyme family K03336 - 3.7.1.22 1.092e-272 866.0
CMS2_k127_5661324_3 Extracellular liganD-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 605.0
CMS2_k127_5661324_4 Thymidylate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 503.0
CMS2_k127_5661324_5 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 493.0
CMS2_k127_5661324_6 PFAM Xylose isomerase domain protein TIM barrel K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 476.0
CMS2_k127_5661324_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 417.0
CMS2_k127_5661324_8 LysR substrate binding domain K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 403.0
CMS2_k127_5661324_9 PFAM Myo-inositol catabolism IolB domain protein K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 392.0
CMS2_k127_5685146_0 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 2.453e-197 627.0
CMS2_k127_5685146_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 558.0
CMS2_k127_5685146_10 STAS domain - - - 0.00000000000000000000000003985 113.0
CMS2_k127_5685146_11 ABC-type transport auxiliary lipoprotein component - - - 0.0000000000000000000003502 106.0
CMS2_k127_5685146_12 LysR substrate binding domain - - - 0.00000000001151 67.0
CMS2_k127_5685146_13 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.00000000001523 70.0
CMS2_k127_5685146_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 436.0
CMS2_k127_5685146_3 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 359.0
CMS2_k127_5685146_4 Sigma factor PP2C-like phosphatases K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 357.0
CMS2_k127_5685146_5 Permease MlaE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002781 282.0
CMS2_k127_5685146_6 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.0000000000000000000000000000000000000000000000000000000000000000001784 243.0
CMS2_k127_5685146_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000006277 186.0
CMS2_k127_5685146_8 MlaD protein K02067 - - 0.00000000000000000000000000000000000000006513 163.0
CMS2_k127_5685146_9 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000001338 122.0
CMS2_k127_569814_0 ATP-binding region, ATPase domain protein K02487,K06596 - - 0.0 1949.0
CMS2_k127_569814_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1571.0
CMS2_k127_569814_10 Aminotransferase K01845 - 5.4.3.8 3.33e-227 710.0
CMS2_k127_569814_11 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 7.867e-218 681.0
CMS2_k127_569814_12 Amidohydrolase family K01465 - 3.5.2.3 6.617e-210 675.0
CMS2_k127_569814_13 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 4.137e-203 640.0
CMS2_k127_569814_14 PFAM ATP-binding region, ATPase domain protein K02668 - 2.7.13.3 5.761e-201 644.0
CMS2_k127_569814_15 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 602.0
CMS2_k127_569814_16 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 586.0
CMS2_k127_569814_17 Type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 574.0
CMS2_k127_569814_18 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 573.0
CMS2_k127_569814_19 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 564.0
CMS2_k127_569814_2 RNB K01147 - 3.1.13.1 3.654e-320 992.0
CMS2_k127_569814_20 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 548.0
CMS2_k127_569814_21 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 534.0
CMS2_k127_569814_22 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 489.0
CMS2_k127_569814_23 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 479.0
CMS2_k127_569814_24 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 467.0
CMS2_k127_569814_25 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 465.0
CMS2_k127_569814_26 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 459.0
CMS2_k127_569814_27 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 454.0
CMS2_k127_569814_28 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 385.0
CMS2_k127_569814_29 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 354.0
CMS2_k127_569814_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.215e-313 978.0
CMS2_k127_569814_30 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 342.0
CMS2_k127_569814_31 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 327.0
CMS2_k127_569814_32 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 318.0
CMS2_k127_569814_33 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 322.0
CMS2_k127_569814_34 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 308.0
CMS2_k127_569814_35 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008848 303.0
CMS2_k127_569814_36 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 294.0
CMS2_k127_569814_37 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 287.0
CMS2_k127_569814_38 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000001276 271.0
CMS2_k127_569814_39 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000001146 263.0
CMS2_k127_569814_4 TIGRFAM type IV-A pilus assembly ATPase PilB K02454,K02504,K02652 - - 7.8e-306 945.0
CMS2_k127_569814_40 uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000719 247.0
CMS2_k127_569814_41 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001048 237.0
CMS2_k127_569814_42 response regulator, receiver K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000000017 229.0
CMS2_k127_569814_43 PFAM response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000000000000003348 218.0
CMS2_k127_569814_44 TIGRFAM MJ0042 family finger-like - - - 0.000000000000000000000000000000000000000000000000000000002116 214.0
CMS2_k127_569814_45 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000004714 196.0
CMS2_k127_569814_46 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000000002049 191.0
CMS2_k127_569814_47 CheW-like domain K02659 - - 0.000000000000000000000000000000000000000000000000001888 187.0
CMS2_k127_569814_48 Protein of unknown function (DUF2726) - - - 0.00000000000000000000000000000000000000000000000006515 186.0
CMS2_k127_569814_49 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000002088 183.0
CMS2_k127_569814_5 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.323e-268 831.0
CMS2_k127_569814_50 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000002675 170.0
CMS2_k127_569814_51 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000001758 166.0
CMS2_k127_569814_52 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000003935 144.0
CMS2_k127_569814_53 rubredoxin - - - 0.0000000000000000000000000000000009934 131.0
CMS2_k127_569814_54 - - - - 0.000000000000000000000000000000001635 134.0
CMS2_k127_569814_55 - - - - 0.000000000000000000000007341 103.0
CMS2_k127_569814_56 - - - - 0.00000000000000000004804 98.0
CMS2_k127_569814_57 - K11275 - - 0.000000000000038 81.0
CMS2_k127_569814_58 - K06950 - - 0.0000000000005101 76.0
CMS2_k127_569814_6 PFAM chemotaxis sensory transducer K02660 - - 8.718e-266 839.0
CMS2_k127_569814_7 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 9.085e-248 772.0
CMS2_k127_569814_8 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.417e-246 767.0
CMS2_k127_569814_9 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.911e-242 758.0
CMS2_k127_5797111_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1011.0
CMS2_k127_5797111_1 Poly-beta-hydroxybutyrate polymerase K03821 - - 1.098e-264 828.0
CMS2_k127_5797111_10 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 446.0
CMS2_k127_5797111_11 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 413.0
CMS2_k127_5797111_12 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 412.0
CMS2_k127_5797111_13 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 373.0
CMS2_k127_5797111_14 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
CMS2_k127_5797111_15 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 299.0
CMS2_k127_5797111_16 Electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002896 276.0
CMS2_k127_5797111_17 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002933 267.0
CMS2_k127_5797111_18 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003772 261.0
CMS2_k127_5797111_19 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000005691 243.0
CMS2_k127_5797111_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 2.952e-207 647.0
CMS2_k127_5797111_20 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000000000000000002639 238.0
CMS2_k127_5797111_21 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000004439 226.0
CMS2_k127_5797111_22 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000313 217.0
CMS2_k127_5797111_23 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000001008 168.0
CMS2_k127_5797111_24 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000003824 130.0
CMS2_k127_5797111_25 Integral membrane protein (DUF2244) - - - 0.000000000000000000000000000000006453 134.0
CMS2_k127_5797111_26 Protein of unknown function (DUF2970) - - - 0.00000000000000000003504 101.0
CMS2_k127_5797111_27 Protein of unknown function (DUF2909) - - - 0.000000000000002389 79.0
CMS2_k127_5797111_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 2.719e-197 623.0
CMS2_k127_5797111_4 Cytochrome c oxidase subunit K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 487.0
CMS2_k127_5797111_5 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 485.0
CMS2_k127_5797111_6 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 470.0
CMS2_k127_5797111_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 461.0
CMS2_k127_5797111_8 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 452.0
CMS2_k127_5797111_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 459.0
CMS2_k127_5951721_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 565.0
CMS2_k127_5951721_1 Thiamine pyrophosphate enzyme, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 489.0
CMS2_k127_5951721_10 Tripartite tricarboxylate transporter TctB family - - - 0.00000007819 61.0
CMS2_k127_5951721_2 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 391.0
CMS2_k127_5951721_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 369.0
CMS2_k127_5951721_4 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 321.0
CMS2_k127_5951721_5 Aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 311.0
CMS2_k127_5951721_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001405 284.0
CMS2_k127_5951721_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002297 255.0
CMS2_k127_5951721_8 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000005278 231.0
CMS2_k127_5951721_9 Isochorismatase family - - - 0.0000000000000000000000000000000001306 141.0
CMS2_k127_6088025_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1131.0
CMS2_k127_6088025_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1077.0
CMS2_k127_6088025_10 alcohol dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 492.0
CMS2_k127_6088025_11 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 298.0
CMS2_k127_6088025_12 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 295.0
CMS2_k127_6088025_13 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002978 277.0
CMS2_k127_6088025_14 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000005901 248.0
CMS2_k127_6088025_15 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000001641 227.0
CMS2_k127_6088025_16 Cell wall-associated K13695,K19303 - - 0.000000000000000000000000000000000000000000000000000000005038 205.0
CMS2_k127_6088025_17 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000004832 153.0
CMS2_k127_6088025_18 FR47-like protein - - - 0.00000000000000000000000000000000007994 141.0
CMS2_k127_6088025_19 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000007746 100.0
CMS2_k127_6088025_2 Large family of predicted nucleotide-binding domains K07175 - - 1.545e-289 898.0
CMS2_k127_6088025_3 PFAM aminotransferase, class I and II K14260 - 2.6.1.2,2.6.1.66 5.787e-245 760.0
CMS2_k127_6088025_4 Threonine synthase K01733 - 4.2.3.1 7.394e-241 755.0
CMS2_k127_6088025_5 homoserine dehydrogenase K00003 - 1.1.1.3 1.611e-232 727.0
CMS2_k127_6088025_6 Exonuclease C-terminal K01141 - 3.1.11.1 1.277e-212 670.0
CMS2_k127_6088025_7 molybdopterin K03750 - 2.10.1.1 7.299e-205 644.0
CMS2_k127_6088025_8 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 567.0
CMS2_k127_6088025_9 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 566.0
CMS2_k127_6140365_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1540.0
CMS2_k127_6140365_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1057.0
CMS2_k127_6140365_10 Biotin carboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 494.0
CMS2_k127_6140365_11 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 469.0
CMS2_k127_6140365_12 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 454.0
CMS2_k127_6140365_13 Von willebrand factor, type a - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 460.0
CMS2_k127_6140365_14 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 447.0
CMS2_k127_6140365_15 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008644 423.0
CMS2_k127_6140365_16 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 422.0
CMS2_k127_6140365_17 Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 411.0
CMS2_k127_6140365_18 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 390.0
CMS2_k127_6140365_19 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 367.0
CMS2_k127_6140365_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.604e-221 692.0
CMS2_k127_6140365_20 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 351.0
CMS2_k127_6140365_21 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 326.0
CMS2_k127_6140365_22 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 329.0
CMS2_k127_6140365_23 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006016 287.0
CMS2_k127_6140365_24 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008469 283.0
CMS2_k127_6140365_25 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007537 271.0
CMS2_k127_6140365_26 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005536 238.0
CMS2_k127_6140365_27 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000000000000001484 224.0
CMS2_k127_6140365_28 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000001274 217.0
CMS2_k127_6140365_29 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000002051 205.0
CMS2_k127_6140365_3 Dehydrogenase K15515 - 1.2.1.81 1.222e-212 670.0
CMS2_k127_6140365_30 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000001677 190.0
CMS2_k127_6140365_31 Protein of unknown function (DUF1345) - - - 0.0000000000000000000000000000000000000000000000004171 179.0
CMS2_k127_6140365_32 - - - - 0.000000000000000000000000000000000007125 152.0
CMS2_k127_6140365_33 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000002165 124.0
CMS2_k127_6140365_34 Flavin reductase like domain - - - 0.0000000000000000000000000001341 116.0
CMS2_k127_6140365_35 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000002488 101.0
CMS2_k127_6140365_36 bacterial OsmY and nodulation domain - - - 0.000000000000000000000816 102.0
CMS2_k127_6140365_37 Domain of unknown function (DUF1841) - - - 0.000000000000000000003371 92.0
CMS2_k127_6140365_38 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000005 99.0
CMS2_k127_6140365_39 transposase IS116 IS110 IS902 family - - - 0.0000000000000000008204 100.0
CMS2_k127_6140365_4 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 2.728e-209 662.0
CMS2_k127_6140365_40 - - - - 0.00000000000000006624 91.0
CMS2_k127_6140365_41 Belongs to the ompA family K03286 - - 0.0000000000002137 77.0
CMS2_k127_6140365_42 Thioesterase-like superfamily - - - 0.000000000003547 66.0
CMS2_k127_6140365_43 Protein of unknown function (DUF1345) - - - 0.00000000001964 75.0
CMS2_k127_6140365_44 PFAM CBS domain containing protein - - - 0.000000001411 58.0
CMS2_k127_6140365_45 Ferritin, Dps family protein K03594 - 1.16.3.1 0.000000005574 58.0
CMS2_k127_6140365_46 - - - - 0.00000007044 56.0
CMS2_k127_6140365_47 - - - - 0.0000004852 53.0
CMS2_k127_6140365_49 Putative transposase - - - 0.00005305 49.0
CMS2_k127_6140365_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.27e-209 669.0
CMS2_k127_6140365_50 Alternative oxidase K17893 - 1.10.3.11 0.0002427 46.0
CMS2_k127_6140365_51 May be involved in recombination K03554 - - 0.0003116 44.0
CMS2_k127_6140365_6 Nitroreductase - - - 4.243e-202 647.0
CMS2_k127_6140365_7 Rieske 2Fe-2S K00499 - 1.14.15.7 4.726e-198 625.0
CMS2_k127_6140365_8 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 600.0
CMS2_k127_6140365_9 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 546.0
CMS2_k127_6144469_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1292.0
CMS2_k127_6144469_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.0 1147.0
CMS2_k127_6144469_10 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 590.0
CMS2_k127_6144469_11 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 554.0
CMS2_k127_6144469_12 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 539.0
CMS2_k127_6144469_13 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 533.0
CMS2_k127_6144469_14 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 514.0
CMS2_k127_6144469_15 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 492.0
CMS2_k127_6144469_16 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 430.0
CMS2_k127_6144469_17 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 403.0
CMS2_k127_6144469_18 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 340.0
CMS2_k127_6144469_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001681 276.0
CMS2_k127_6144469_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.159e-302 949.0
CMS2_k127_6144469_20 Tryptophan halogenase K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000002709 265.0
CMS2_k127_6144469_21 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000003882 255.0
CMS2_k127_6144469_22 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000461 255.0
CMS2_k127_6144469_23 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000000000000003228 237.0
CMS2_k127_6144469_24 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000007633 235.0
CMS2_k127_6144469_25 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000000000001519 201.0
CMS2_k127_6144469_26 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000003681 174.0
CMS2_k127_6144469_27 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000002075 164.0
CMS2_k127_6144469_28 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000001421 156.0
CMS2_k127_6144469_29 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000002256 121.0
CMS2_k127_6144469_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 7.059e-297 920.0
CMS2_k127_6144469_30 PFAM PsiF repeat protein - - - 0.000000000000007895 85.0
CMS2_k127_6144469_31 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.000000000001948 70.0
CMS2_k127_6144469_32 PFAM Glutaredoxin - - - 0.00000001451 57.0
CMS2_k127_6144469_33 Redoxin - - - 0.00005012 56.0
CMS2_k127_6144469_4 Arginyl-tRNA synthetase K01887 - 6.1.1.19 9.046e-279 871.0
CMS2_k127_6144469_5 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 2.953e-271 841.0
CMS2_k127_6144469_6 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 4.397e-257 797.0
CMS2_k127_6144469_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.235e-212 672.0
CMS2_k127_6144469_8 cytochrome C K02198 - - 7.559e-209 656.0
CMS2_k127_6144469_9 Serine threonine protein kinase K12132 - 2.7.11.1 4.084e-201 638.0
CMS2_k127_6163557_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 3.742e-270 841.0
CMS2_k127_6163557_1 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 584.0
CMS2_k127_6163557_10 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000005926 154.0
CMS2_k127_6163557_2 type II secretion system protein E K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 561.0
CMS2_k127_6163557_3 Glucose sorbosone K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 533.0
CMS2_k127_6163557_4 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 522.0
CMS2_k127_6163557_5 PFAM TatD-related deoxyribonuclease K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 355.0
CMS2_k127_6163557_6 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 354.0
CMS2_k127_6163557_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 320.0
CMS2_k127_6163557_8 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 294.0
CMS2_k127_6163557_9 G T U mismatch-specific DNA glycosylase K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000005773 257.0
CMS2_k127_6164926_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1320.0
CMS2_k127_6164926_1 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.0 1154.0
CMS2_k127_6164926_10 PFAM Type II secretion system protein E K02454 - - 1.723e-248 774.0
CMS2_k127_6164926_11 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 4.464e-215 673.0
CMS2_k127_6164926_12 Putative nucleotidyltransferase substrate binding domain K07182 - - 2.411e-206 662.0
CMS2_k127_6164926_13 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 3.424e-206 646.0
CMS2_k127_6164926_14 Transmembrane secretion effector - - - 6.273e-204 648.0
CMS2_k127_6164926_15 Belongs to the binding-protein-dependent transport system permease family K01998 - - 2.124e-200 627.0
CMS2_k127_6164926_16 AMP-binding enzyme K01912 - 6.2.1.30 5.735e-196 623.0
CMS2_k127_6164926_17 general secretion pathway protein K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 561.0
CMS2_k127_6164926_18 PFAM ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 558.0
CMS2_k127_6164926_19 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 529.0
CMS2_k127_6164926_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1057.0
CMS2_k127_6164926_20 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 518.0
CMS2_k127_6164926_21 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 494.0
CMS2_k127_6164926_22 PFAM 5-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 477.0
CMS2_k127_6164926_23 FAD dependent oxidoreductase K00273 - 1.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 484.0
CMS2_k127_6164926_24 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 487.0
CMS2_k127_6164926_25 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 459.0
CMS2_k127_6164926_26 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 453.0
CMS2_k127_6164926_27 General secretion pathway K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 426.0
CMS2_k127_6164926_28 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 413.0
CMS2_k127_6164926_29 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 409.0
CMS2_k127_6164926_3 ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1026.0
CMS2_k127_6164926_30 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 371.0
CMS2_k127_6164926_31 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 364.0
CMS2_k127_6164926_32 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 303.0
CMS2_k127_6164926_33 Type II secretion system (T2SS), protein N K02463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 295.0
CMS2_k127_6164926_34 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002567 279.0
CMS2_k127_6164926_35 Protein of unknown function (DUF2726) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001878 279.0
CMS2_k127_6164926_36 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001569 269.0
CMS2_k127_6164926_37 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004344 256.0
CMS2_k127_6164926_38 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000000000002593 236.0
CMS2_k127_6164926_39 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000137 238.0
CMS2_k127_6164926_4 Molecular chaperone. Has ATPase activity K04079 - - 7.95e-322 994.0
CMS2_k127_6164926_40 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001142 244.0
CMS2_k127_6164926_41 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000009767 243.0
CMS2_k127_6164926_42 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000000000000000002874 224.0
CMS2_k127_6164926_43 Prokaryotic N-terminal methylation motif K02459 - - 0.0000000000000000000000000000000000000000000000000000000000000004589 226.0
CMS2_k127_6164926_44 - - - - 0.000000000000000000000000000000000000000000000000000000001257 205.0
CMS2_k127_6164926_45 Domain of unknown function (DUF1854) - - - 0.00000000000000000000000000000000000000000000000000005473 193.0
CMS2_k127_6164926_46 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000002423 202.0
CMS2_k127_6164926_47 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000005946 188.0
CMS2_k127_6164926_48 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000004619 185.0
CMS2_k127_6164926_49 general secretion pathway protein K02458 - - 0.00000000000000000000000000000000000000000000005425 173.0
CMS2_k127_6164926_5 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.052e-296 921.0
CMS2_k127_6164926_50 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000000000000000000000000000000000001829 164.0
CMS2_k127_6164926_51 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000003432 144.0
CMS2_k127_6164926_52 PFAM General secretion pathway, M protein K02462 - - 0.00000000000000000000000000000000003014 148.0
CMS2_k127_6164926_53 general secretion pathway protein K02452 - - 0.00000000000000000000001937 108.0
CMS2_k127_6164926_54 ABC-type transport auxiliary lipoprotein component - - - 0.0000000000000001967 93.0
CMS2_k127_6164926_55 Phosphoribosyltransferase K00768 - 2.4.2.21 0.000000000000001354 77.0
CMS2_k127_6164926_56 - - - - 0.0000000000003432 75.0
CMS2_k127_6164926_6 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 9.193e-281 879.0
CMS2_k127_6164926_7 general secretion pathway protein K02453 - - 1.232e-273 861.0
CMS2_k127_6164926_8 SMART alpha amylase, catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 2.244e-273 844.0
CMS2_k127_6164926_9 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 8.701e-253 784.0
CMS2_k127_6166550_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.286e-217 682.0
CMS2_k127_6166550_1 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 512.0
CMS2_k127_6166550_2 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 488.0
CMS2_k127_6166550_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 460.0
CMS2_k127_6166550_4 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001694 254.0
CMS2_k127_6166550_5 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000000000000000000000000000000000000000000000035 195.0
CMS2_k127_6171391_0 AcrB/AcrD/AcrF family K18138,K18146,K18902 - - 0.0 1522.0
CMS2_k127_6171391_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1448.0
CMS2_k127_6171391_10 peptidase U62, modulator of DNA gyrase K03592 - - 1.511e-223 704.0
CMS2_k127_6171391_11 Serine threonine protein kinase - - - 5.03e-199 621.0
CMS2_k127_6171391_12 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 609.0
CMS2_k127_6171391_13 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 584.0
CMS2_k127_6171391_14 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 548.0
CMS2_k127_6171391_15 phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 523.0
CMS2_k127_6171391_16 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 483.0
CMS2_k127_6171391_17 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 496.0
CMS2_k127_6171391_18 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 451.0
CMS2_k127_6171391_19 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 442.0
CMS2_k127_6171391_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1130.0
CMS2_k127_6171391_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 443.0
CMS2_k127_6171391_21 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 422.0
CMS2_k127_6171391_22 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 401.0
CMS2_k127_6171391_23 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 407.0
CMS2_k127_6171391_24 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 408.0
CMS2_k127_6171391_25 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 383.0
CMS2_k127_6171391_26 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 353.0
CMS2_k127_6171391_27 lytic transglycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 351.0
CMS2_k127_6171391_28 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 338.0
CMS2_k127_6171391_29 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 319.0
CMS2_k127_6171391_3 GMC oxidoreductase K03333 - 1.1.3.6 1.44e-316 972.0
CMS2_k127_6171391_30 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 317.0
CMS2_k127_6171391_31 molybdenum cofactor K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 316.0
CMS2_k127_6171391_32 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 304.0
CMS2_k127_6171391_33 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 297.0
CMS2_k127_6171391_34 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 301.0
CMS2_k127_6171391_35 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004369 269.0
CMS2_k127_6171391_36 Pilus assembly protein PilX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006805 265.0
CMS2_k127_6171391_37 Belongs to the DnaA family K10763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003458 263.0
CMS2_k127_6171391_38 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004397 245.0
CMS2_k127_6171391_39 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000003163 252.0
CMS2_k127_6171391_4 Belongs to the UbiD family K03182 - 4.1.1.98 1.738e-272 845.0
CMS2_k127_6171391_40 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001212 245.0
CMS2_k127_6171391_41 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000166 225.0
CMS2_k127_6171391_42 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000004003 229.0
CMS2_k127_6171391_43 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000000001352 223.0
CMS2_k127_6171391_44 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000000008924 216.0
CMS2_k127_6171391_45 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000007131 203.0
CMS2_k127_6171391_46 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000000000000000007319 192.0
CMS2_k127_6171391_47 General secretion pathway protein K02672 - - 0.0000000000000000000000000000000000000000000000000005249 193.0
CMS2_k127_6171391_48 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0010564,GO:0010948,GO:0031333,GO:0031668,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0033554,GO:0034260,GO:0043086,GO:0043087,GO:0043254,GO:0044087,GO:0044092,GO:0045786,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051302,GO:0051336,GO:0051346,GO:0051716,GO:0051726,GO:0051782,GO:0065007,GO:0065009,GO:0071496,GO:1903664,GO:1903665,GO:2000241,GO:2000242,GO:2000244,GO:2000245 - 0.00000000000000000000000000000000000000000000000001988 189.0
CMS2_k127_6171391_49 Ribbon-helix-helix domain - - - 0.0000000000000000000000000000000000000000000000002087 178.0
CMS2_k127_6171391_5 TRAP dicarboxylate transporter, DctM subunit K03299 - - 3.101e-262 818.0
CMS2_k127_6171391_50 Type II transport protein GspH K08084 - - 0.0000000000000000000000000000000000000000491 158.0
CMS2_k127_6171391_51 Putative phosphatase (DUF442) - - - 0.0000000000000000000000000000000000000001309 155.0
CMS2_k127_6171391_52 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000000001099 148.0
CMS2_k127_6171391_53 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000000003042 133.0
CMS2_k127_6171391_54 coenzyme F420 binding K07226 - - 0.00000000000000000000000000000001836 134.0
CMS2_k127_6171391_55 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000008123 126.0
CMS2_k127_6171391_56 FecR protein - - - 0.0000000000000000000000000005451 122.0
CMS2_k127_6171391_57 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000000000000000000000000007347 115.0
CMS2_k127_6171391_58 type IV pilus modification protein PilV - - - 0.0000000000000000000000004238 123.0
CMS2_k127_6171391_59 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000001007 110.0
CMS2_k127_6171391_6 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.591e-242 754.0
CMS2_k127_6171391_60 Type II transport protein GspH K08084 - - 0.0000000002211 72.0
CMS2_k127_6171391_61 Glutathione S-transferase, C-terminal domain K04097 - 2.5.1.18,5.3.99.2 0.0001504 52.0
CMS2_k127_6171391_7 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 3.737e-229 723.0
CMS2_k127_6171391_8 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 3.638e-228 717.0
CMS2_k127_6171391_9 Glucose / Sorbosone dehydrogenase - - - 3.982e-227 709.0
CMS2_k127_6187729_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 1.373e-290 900.0
CMS2_k127_6187729_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 501.0
CMS2_k127_6187729_10 Fumarase C-terminus K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 318.0
CMS2_k127_6187729_11 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 329.0
CMS2_k127_6187729_12 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 296.0
CMS2_k127_6187729_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002954 251.0
CMS2_k127_6187729_14 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002176 271.0
CMS2_k127_6187729_15 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002811 248.0
CMS2_k127_6187729_16 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000000000000000005676 179.0
CMS2_k127_6187729_17 Trypsin - - - 0.00000000000000000000000000000000000004577 149.0
CMS2_k127_6187729_18 succinate dehydrogenase K00247 - - 0.0000000000000000000000000000005858 131.0
CMS2_k127_6187729_19 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.000000000000000000000000007012 113.0
CMS2_k127_6187729_2 heat shock protein DnaJ K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 456.0
CMS2_k127_6187729_20 MerR HTH family regulatory protein K18997 - - 0.00000000000000000000001505 105.0
CMS2_k127_6187729_3 Fumarate hydratase (Fumerase) K01677,K03779 - 4.2.1.2,4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 461.0
CMS2_k127_6187729_4 ABC-type nitrate sulfonate bicarbonate transport system, periplasmic component K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 451.0
CMS2_k127_6187729_5 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 434.0
CMS2_k127_6187729_6 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 408.0
CMS2_k127_6187729_7 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 391.0
CMS2_k127_6187729_8 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 372.0
CMS2_k127_6187729_9 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 336.0
CMS2_k127_6226917_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.509e-204 640.0
CMS2_k127_6226917_1 2-keto-4-pentenoate hydratase K01617 - 4.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000344 227.0
CMS2_k127_6242789_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1140.0
CMS2_k127_6242789_1 Transport of potassium into the cell K03549 - - 0.0 1037.0
CMS2_k127_6242789_10 Amidohydrolase family K05603 - 3.5.3.13 3.653e-197 625.0
CMS2_k127_6242789_11 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 591.0
CMS2_k127_6242789_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 533.0
CMS2_k127_6242789_13 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 518.0
CMS2_k127_6242789_14 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 467.0
CMS2_k127_6242789_15 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 466.0
CMS2_k127_6242789_16 Enoyl-CoA hydratase/isomerase K20036 - 4.2.1.155 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 436.0
CMS2_k127_6242789_17 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 413.0
CMS2_k127_6242789_18 Pfam Binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 406.0
CMS2_k127_6242789_19 Aldose 1-epimerase K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007917 404.0
CMS2_k127_6242789_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0 1002.0
CMS2_k127_6242789_20 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 377.0
CMS2_k127_6242789_21 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 376.0
CMS2_k127_6242789_22 related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 367.0
CMS2_k127_6242789_23 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 363.0
CMS2_k127_6242789_24 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 346.0
CMS2_k127_6242789_25 UTRA K05836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 321.0
CMS2_k127_6242789_26 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 322.0
CMS2_k127_6242789_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001904 295.0
CMS2_k127_6242789_28 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009122 267.0
CMS2_k127_6242789_29 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001228 252.0
CMS2_k127_6242789_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.891e-301 927.0
CMS2_k127_6242789_30 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000002143 226.0
CMS2_k127_6242789_31 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000006336 223.0
CMS2_k127_6242789_32 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000000000007991 214.0
CMS2_k127_6242789_33 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000166 208.0
CMS2_k127_6242789_34 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000002551 201.0
CMS2_k127_6242789_35 cytochrome c5 - - - 0.0000000000000000000000000000000000000000000000000007344 199.0
CMS2_k127_6242789_36 ATP synthase I chain K02116 - - 0.000000000000000000000000000000000000000000000003379 177.0
CMS2_k127_6242789_37 PFAM Cytochrome C - - - 0.000000000000000000000000000000000000000000007539 168.0
CMS2_k127_6242789_38 PFAM conserved - - - 0.000000000000000000000000000000000000000004695 163.0
CMS2_k127_6242789_39 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000000008487 146.0
CMS2_k127_6242789_4 AMP-binding enzyme K12508 - 6.2.1.34 2.174e-275 866.0
CMS2_k127_6242789_40 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000004194 153.0
CMS2_k127_6242789_41 17 kDa surface antigen - - - 0.000000000000000000000000000000000002347 151.0
CMS2_k127_6242789_42 PFAM conserved - - - 0.0000000000004752 73.0
CMS2_k127_6242789_5 Amidohydrolase family - - - 2.806e-263 824.0
CMS2_k127_6242789_6 glutamate--cysteine ligase K01919 - 6.3.2.2 1.148e-255 791.0
CMS2_k127_6242789_7 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.899e-225 707.0
CMS2_k127_6242789_8 ammonium transporter K03320 - - 3.367e-210 668.0
CMS2_k127_6242789_9 Aromatic amino acid lyase K01745 - 4.3.1.3 7.63e-202 662.0
CMS2_k127_6303889_0 FAD linked oxidase domain protein - - - 0.0 1580.0
CMS2_k127_6303889_1 histidine kinase A domain protein - - - 0.0 1298.0
CMS2_k127_6303889_10 ABC-type sugar K02025,K10237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 511.0
CMS2_k127_6303889_11 PFAM NAD-dependent epimerase dehydratase K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 506.0
CMS2_k127_6303889_12 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 497.0
CMS2_k127_6303889_13 ABC transporter K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 507.0
CMS2_k127_6303889_14 PFAM Pyruvate carboxyltransferase K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 492.0
CMS2_k127_6303889_15 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 426.0
CMS2_k127_6303889_16 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 433.0
CMS2_k127_6303889_17 6-phosphogluconate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 419.0
CMS2_k127_6303889_18 Lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 412.0
CMS2_k127_6303889_19 KR domain K21883 - 1.1.1.401 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 357.0
CMS2_k127_6303889_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1027.0
CMS2_k127_6303889_20 DSBA-like thioredoxin domain K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 346.0
CMS2_k127_6303889_21 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 349.0
CMS2_k127_6303889_22 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 324.0
CMS2_k127_6303889_23 Class II aldolase adducin family protein K01628,K22130 - 4.1.1.104,4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 297.0
CMS2_k127_6303889_24 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 302.0
CMS2_k127_6303889_25 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K08319 - 1.1.1.31,1.1.1.411 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 307.0
CMS2_k127_6303889_26 2-hydroxychromene-2-carboxylate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000576 270.0
CMS2_k127_6303889_27 YbaK prolyl-tRNA synthetase associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001965 262.0
CMS2_k127_6303889_28 membrane - - - 0.0000000000000000000000000000000000000000000000000000000001144 211.0
CMS2_k127_6303889_29 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000001964 192.0
CMS2_k127_6303889_3 Carboxyl transferase domain K01969 - 6.4.1.4 2.008e-310 957.0
CMS2_k127_6303889_30 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000000000000002328 182.0
CMS2_k127_6303889_31 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000001347 181.0
CMS2_k127_6303889_32 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000009703 172.0
CMS2_k127_6303889_33 - - - - 0.0000000000000000000000000000000000000000002953 160.0
CMS2_k127_6303889_34 Domain of unknown function (DUF4212) - - - 0.0000000000000000000000000000000000000003607 149.0
CMS2_k127_6303889_35 - - - - 0.0000000000000000004198 89.0
CMS2_k127_6303889_36 Protein of unknown function (DUF1289) K06938 - - 0.000000000000007354 83.0
CMS2_k127_6303889_37 Regulatory protein GntR HTH - - - 0.0000000006801 60.0
CMS2_k127_6303889_4 DNA polymerase III K02342 - 2.7.7.7 1.869e-299 936.0
CMS2_k127_6303889_5 carboxylase K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 5.99e-293 916.0
CMS2_k127_6303889_6 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 8.418e-237 741.0
CMS2_k127_6303889_7 Bacterial extracellular solute-binding protein K02027 - - 1.039e-218 685.0
CMS2_k127_6303889_8 Putative nucleotidyltransferase substrate binding domain K07182 - - 2.08e-209 666.0
CMS2_k127_6303889_9 PFAM type III effector Hrp-dependent outers K21948 - 2.7.1.217 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 569.0
CMS2_k127_6308465_0 Cytochrome c554 and c-prime - - - 1.084e-220 704.0
CMS2_k127_6308465_1 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000002062 132.0
CMS2_k127_6308465_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000001258 96.0
CMS2_k127_6308465_3 Cytochrome c - - - 0.00000000000000000001296 105.0
CMS2_k127_6308465_4 Cytochrome c K08738 - - 0.0000000000000000003999 90.0
CMS2_k127_6338796_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1538.0
CMS2_k127_6338796_1 NADPH-dependent glutamate synthase beta - - - 0.0 1154.0
CMS2_k127_6338796_10 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 407.0
CMS2_k127_6338796_11 Virulence factor membrane-bound polymerase, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 405.0
CMS2_k127_6338796_12 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 385.0
CMS2_k127_6338796_13 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 327.0
CMS2_k127_6338796_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 323.0
CMS2_k127_6338796_15 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 288.0
CMS2_k127_6338796_16 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001032 281.0
CMS2_k127_6338796_17 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001504 270.0
CMS2_k127_6338796_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004259 264.0
CMS2_k127_6338796_19 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001743 259.0
CMS2_k127_6338796_2 Fe-S oxidoreductase K21834 - - 2.865e-314 964.0
CMS2_k127_6338796_20 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000007346 255.0
CMS2_k127_6338796_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006572 265.0
CMS2_k127_6338796_22 Cas6 Crispr - - - 0.00000000000000000000000000000000000000000000000000000000000000000002196 265.0
CMS2_k127_6338796_23 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000293 237.0
CMS2_k127_6338796_24 sulfur relay protein TusD DsrE K07235 - - 0.000000000000000000000000000000000000000000000000000000000000003285 218.0
CMS2_k127_6338796_25 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000000000000000000008006 199.0
CMS2_k127_6338796_26 Sulfur relay protein TusC DsrF K07236 - - 0.000000000000000000000000000000000000000000000000000002756 199.0
CMS2_k127_6338796_27 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000004208 185.0
CMS2_k127_6338796_28 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000414 185.0
CMS2_k127_6338796_29 PFAM Membrane protein of K08972 - - 0.0000000000000000000000000000000000000000000009042 173.0
CMS2_k127_6338796_3 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.316e-267 829.0
CMS2_k127_6338796_30 Peptidase S24-like - - - 0.00000000000000000000000000000000000000000004142 169.0
CMS2_k127_6338796_31 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000000000000003264 165.0
CMS2_k127_6338796_32 - - - - 0.00000000000000000000000000000000000000005241 164.0
CMS2_k127_6338796_33 DsrH like protein K07237 - - 0.0000000000000000000000000000000003545 134.0
CMS2_k127_6338796_34 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000002347 128.0
CMS2_k127_6338796_35 - - - - 0.000000000000000000000000000324 122.0
CMS2_k127_6338796_36 - - - - 0.0000000000000000000000000005751 115.0
CMS2_k127_6338796_37 - - - - 0.000000000000000000000006456 102.0
CMS2_k127_6338796_38 - - - - 0.00000000000001501 79.0
CMS2_k127_6338796_39 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0009687 42.0
CMS2_k127_6338796_4 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 2.944e-236 740.0
CMS2_k127_6338796_5 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 6.71e-235 726.0
CMS2_k127_6338796_6 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 530.0
CMS2_k127_6338796_7 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 522.0
CMS2_k127_6338796_8 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 522.0
CMS2_k127_6338796_9 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 413.0
CMS2_k127_6416213_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1120.0
CMS2_k127_6416213_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1093.0
CMS2_k127_6416213_10 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.565e-199 626.0
CMS2_k127_6416213_11 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 597.0
CMS2_k127_6416213_12 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 564.0
CMS2_k127_6416213_13 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 549.0
CMS2_k127_6416213_14 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 535.0
CMS2_k127_6416213_15 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 496.0
CMS2_k127_6416213_16 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 457.0
CMS2_k127_6416213_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 456.0
CMS2_k127_6416213_18 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 434.0
CMS2_k127_6416213_19 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 425.0
CMS2_k127_6416213_2 acetolactate synthase K01652 - 2.2.1.6 0.0 1088.0
CMS2_k127_6416213_20 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 396.0
CMS2_k127_6416213_21 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 364.0
CMS2_k127_6416213_22 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 351.0
CMS2_k127_6416213_23 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006774 328.0
CMS2_k127_6416213_24 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 320.0
CMS2_k127_6416213_25 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 306.0
CMS2_k127_6416213_26 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 314.0
CMS2_k127_6416213_27 synthase small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 293.0
CMS2_k127_6416213_28 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000004661 268.0
CMS2_k127_6416213_29 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000000002901 214.0
CMS2_k127_6416213_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.826e-295 909.0
CMS2_k127_6416213_30 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.00000000000000000000000000000000000000000000000000000000007823 219.0
CMS2_k127_6416213_31 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000323 211.0
CMS2_k127_6416213_32 Protein of unknown function (DUF3106) - - - 0.0000000000000000000000000000000000000000000000000000000003492 211.0
CMS2_k127_6416213_33 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000000000005051 192.0
CMS2_k127_6416213_34 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000000000000008514 199.0
CMS2_k127_6416213_35 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000104 162.0
CMS2_k127_6416213_36 Protein of unknown function (DUF3619) - - - 0.0000000000000000000000000000000039 137.0
CMS2_k127_6416213_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.858e-284 882.0
CMS2_k127_6416213_5 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.063e-264 818.0
CMS2_k127_6416213_6 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 1.523e-242 762.0
CMS2_k127_6416213_7 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 6.57e-239 742.0
CMS2_k127_6416213_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 3.057e-214 673.0
CMS2_k127_6416213_9 Aminotransferase K14267 - 2.6.1.17 2.758e-207 649.0
CMS2_k127_6438749_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 2.406e-200 640.0
CMS2_k127_6438749_1 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 578.0
CMS2_k127_6438749_2 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 436.0
CMS2_k127_6438749_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 375.0
CMS2_k127_6438749_4 Uroporphyrin-III C-methyltransferase K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 376.0
CMS2_k127_6438749_5 Bacterial regulatory proteins, luxR family K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 341.0
CMS2_k127_6438749_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000005452 172.0
CMS2_k127_6438749_7 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.000000000000000000000000000000000000000000000006742 174.0
CMS2_k127_6438749_8 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.00000000000000000000000000000000000000004313 153.0
CMS2_k127_6438749_9 Iron-sulphur cluster biosynthesis K13628 - - 0.0000000000000000000001012 104.0
CMS2_k127_6499818_0 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 512.0
CMS2_k127_6499818_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 461.0
CMS2_k127_6499818_2 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 385.0
CMS2_k127_6499818_3 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 368.0
CMS2_k127_6499818_4 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000046 276.0
CMS2_k127_6499818_5 Putative transposase - - - 0.000000000000000000000000000000000001432 149.0
CMS2_k127_6499818_6 Evidence 2b Function of strongly homologous gene K07497 - - 0.00000000000000000000000003801 111.0
CMS2_k127_6553199_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.697e-226 711.0
CMS2_k127_6553199_1 Binding-protein-dependent transport system inner membrane component K02054 - - 5.651e-199 633.0
CMS2_k127_6553199_2 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 577.0
CMS2_k127_6553199_3 Belongs to the arginase family K12255 - 3.5.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 571.0
CMS2_k127_6553199_4 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 532.0
CMS2_k127_6553199_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 535.0
CMS2_k127_6553199_6 III protein, CoA-transferase family K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 480.0
CMS2_k127_6553199_7 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000649 272.0
CMS2_k127_6553199_8 Plasmid segregation protein ParM K18640 - - 0.0000000000000000000000000000000007309 144.0
CMS2_k127_6553199_9 methyltransferase - - - 0.000000000001645 77.0
CMS2_k127_6589029_0 ABC transporter K06147 - - 1.139e-303 940.0
CMS2_k127_6589029_1 UDP-glucose 4-epimerase K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 564.0
CMS2_k127_6589029_10 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 388.0
CMS2_k127_6589029_11 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 381.0
CMS2_k127_6589029_12 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 357.0
CMS2_k127_6589029_13 Protein of unknown function (DUF3025) - - - 0.0000000000000000000000000000000000000000000000000000000000000007392 238.0
CMS2_k127_6589029_14 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000000000000000000000000000001944 202.0
CMS2_k127_6589029_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 559.0
CMS2_k127_6589029_3 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 547.0
CMS2_k127_6589029_4 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 545.0
CMS2_k127_6589029_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 515.0
CMS2_k127_6589029_6 LysR substrate binding domain K21645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 467.0
CMS2_k127_6589029_7 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 443.0
CMS2_k127_6589029_8 PFAM ABC transporter K10004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 445.0
CMS2_k127_6589029_9 acid transport system permease K09970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 398.0
CMS2_k127_6608159_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0 1060.0
CMS2_k127_6608159_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 1.131e-209 662.0
CMS2_k127_6608159_10 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 369.0
CMS2_k127_6608159_11 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 351.0
CMS2_k127_6608159_12 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 339.0
CMS2_k127_6608159_13 short-chain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 338.0
CMS2_k127_6608159_14 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009135 287.0
CMS2_k127_6608159_15 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003218 280.0
CMS2_k127_6608159_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007029 267.0
CMS2_k127_6608159_17 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000000000000000000008065 237.0
CMS2_k127_6608159_18 PFAM regulatory protein AsnC Lrp family K03719 - - 0.000000000000000000000000000000000000000000000000000000001203 205.0
CMS2_k127_6608159_19 Ribosomal-protein-alanine acetyltransferase K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000000000000007232 190.0
CMS2_k127_6608159_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 601.0
CMS2_k127_6608159_20 Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000000000000000000000000001378 170.0
CMS2_k127_6608159_21 - - - - 0.00000000000000000000000000000000000000006881 164.0
CMS2_k127_6608159_22 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000000000000005794 156.0
CMS2_k127_6608159_23 Protein of unknown function (DUF2905) - - - 0.000000000000000004286 97.0
CMS2_k127_6608159_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 585.0
CMS2_k127_6608159_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 497.0
CMS2_k127_6608159_5 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 488.0
CMS2_k127_6608159_6 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 410.0
CMS2_k127_6608159_7 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 401.0
CMS2_k127_6608159_8 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 356.0
CMS2_k127_6608159_9 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 358.0
CMS2_k127_6674321_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 551.0
CMS2_k127_6674321_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 471.0
CMS2_k127_6674321_2 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 374.0
CMS2_k127_6674321_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 326.0
CMS2_k127_6674321_4 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000002008 269.0
CMS2_k127_6674321_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000002392 84.0
CMS2_k127_6674321_6 - - - - 0.00000001223 57.0
CMS2_k127_6694754_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1122.0
CMS2_k127_6694754_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1086.0
CMS2_k127_6694754_10 VWA domain containing CoxE-like protein K09989 - - 9.501e-235 730.0
CMS2_k127_6694754_11 Urate oxidase N-terminal - - - 6.305e-233 726.0
CMS2_k127_6694754_12 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596 - 4.1.1.64 2.255e-227 713.0
CMS2_k127_6694754_13 peptidase dimerisation domain protein - - - 9.639e-221 692.0
CMS2_k127_6694754_14 MOFRL family K11529 - 2.7.1.165 8.535e-217 679.0
CMS2_k127_6694754_15 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.787e-216 680.0
CMS2_k127_6694754_16 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K00104 - 1.1.2.3,1.1.3.15 3.623e-214 668.0
CMS2_k127_6694754_17 Belongs to the peptidase S1C family K04771 - 3.4.21.107 3.294e-208 657.0
CMS2_k127_6694754_18 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 3.985e-202 641.0
CMS2_k127_6694754_19 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.901e-201 640.0
CMS2_k127_6694754_2 Belongs to the TPP enzyme family K01608 - 4.1.1.47 0.0 1060.0
CMS2_k127_6694754_20 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 1.184e-194 614.0
CMS2_k127_6694754_21 deacetylase K01452 - 3.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 602.0
CMS2_k127_6694754_22 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 588.0
CMS2_k127_6694754_23 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 543.0
CMS2_k127_6694754_24 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 520.0
CMS2_k127_6694754_25 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 521.0
CMS2_k127_6694754_26 surface antigen K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 551.0
CMS2_k127_6694754_27 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 503.0
CMS2_k127_6694754_28 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 497.0
CMS2_k127_6694754_29 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 501.0
CMS2_k127_6694754_3 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 5.718e-317 980.0
CMS2_k127_6694754_30 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 485.0
CMS2_k127_6694754_31 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 474.0
CMS2_k127_6694754_32 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 469.0
CMS2_k127_6694754_33 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 466.0
CMS2_k127_6694754_34 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007946 461.0
CMS2_k127_6694754_35 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 445.0
CMS2_k127_6694754_36 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 447.0
CMS2_k127_6694754_37 peptidase S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 437.0
CMS2_k127_6694754_38 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 419.0
CMS2_k127_6694754_39 AAA domain K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 411.0
CMS2_k127_6694754_4 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 5.462e-291 916.0
CMS2_k127_6694754_40 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 414.0
CMS2_k127_6694754_41 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 402.0
CMS2_k127_6694754_42 Short-chain dehydrogenase reductase sdr K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 369.0
CMS2_k127_6694754_43 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 363.0
CMS2_k127_6694754_44 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 351.0
CMS2_k127_6694754_45 PFAM MucB RseB family protein K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 349.0
CMS2_k127_6694754_46 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 325.0
CMS2_k127_6694754_47 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 328.0
CMS2_k127_6694754_48 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 314.0
CMS2_k127_6694754_49 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 313.0
CMS2_k127_6694754_5 TamB, inner membrane protein subunit of TAM complex K09800 - - 4.859e-281 921.0
CMS2_k127_6694754_50 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 316.0
CMS2_k127_6694754_51 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 313.0
CMS2_k127_6694754_52 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 298.0
CMS2_k127_6694754_53 Cytochrome c class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 290.0
CMS2_k127_6694754_54 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 293.0
CMS2_k127_6694754_55 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 295.0
CMS2_k127_6694754_56 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004909 266.0
CMS2_k127_6694754_57 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001576 264.0
CMS2_k127_6694754_58 Cmp dcmp deaminase zinc-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000008537 239.0
CMS2_k127_6694754_59 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000007348 223.0
CMS2_k127_6694754_6 Belongs to the aldehyde dehydrogenase family K00141 - 1.2.1.28 6.543e-280 865.0
CMS2_k127_6694754_60 TIGRFAM Cu(I)-responsive transcriptional regulator K19591 - - 0.0000000000000000000000000000000000000000000000000000003172 198.0
CMS2_k127_6694754_61 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000003739 210.0
CMS2_k127_6694754_62 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000003245 190.0
CMS2_k127_6694754_63 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000000000000000000009869 190.0
CMS2_k127_6694754_64 - - - - 0.000000000000000000000000000000000000000000000000001246 188.0
CMS2_k127_6694754_65 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596 - 4.1.1.64 0.00000000000000000000000000000000000000000004174 162.0
CMS2_k127_6694754_66 PFAM Rieske 2Fe-2S domain protein - - - 0.0000000000000000000000000000000000000000001066 169.0
CMS2_k127_6694754_67 Domain of unknown function (DUF4845) - - - 0.000000000000000000000000000000000000000004906 158.0
CMS2_k127_6694754_68 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000000004957 147.0
CMS2_k127_6694754_69 PFAM Anti sigma-E protein RseA K03597 - - 0.00000000000000000000000000000007662 132.0
CMS2_k127_6694754_7 O-methyltransferase activity - - - 1.178e-265 836.0
CMS2_k127_6694754_70 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000007335 119.0
CMS2_k127_6694754_71 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000001141 99.0
CMS2_k127_6694754_72 mercury ion transmembrane transporter activity K07089,K07213 - - 0.00000000000000000111 87.0
CMS2_k127_6694754_74 Transposase DDE domain group 1 - - - 0.00000000000002652 83.0
CMS2_k127_6694754_75 COG3328 Transposase and inactivated derivatives - - - 0.0000005872 55.0
CMS2_k127_6694754_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.964e-238 742.0
CMS2_k127_6694754_9 PFAM Xanthine uracil vitamin C permease K03458 - - 3.294e-237 742.0
CMS2_k127_6712899_0 RNB K01147 - 3.1.13.1 3.123e-218 688.0
CMS2_k127_6712899_1 Alternative oxidase K17893 - 1.10.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 326.0
CMS2_k127_6712899_10 AI-2E family transporter - - - 0.000000000000000000000000000006604 121.0
CMS2_k127_6712899_11 AI-2E family transporter - - - 0.0000000000000000000002476 106.0
CMS2_k127_6712899_12 oxidoreductase - - - 0.000000000000000000008062 96.0
CMS2_k127_6712899_13 Dodecin K09165 - - 0.000000000000000002902 96.0
CMS2_k127_6712899_14 - - - - 0.00000000000000003375 91.0
CMS2_k127_6712899_15 - - - - 0.00000000000001111 79.0
CMS2_k127_6712899_16 - - - - 0.00000000001914 68.0
CMS2_k127_6712899_17 - - - - 0.00000004626 58.0
CMS2_k127_6712899_18 Glucose / Sorbosone dehydrogenase - - - 0.000000416 62.0
CMS2_k127_6712899_19 - - - - 0.0000006047 52.0
CMS2_k127_6712899_2 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 318.0
CMS2_k127_6712899_20 - - - - 0.000001192 57.0
CMS2_k127_6712899_21 - - - - 0.00002564 52.0
CMS2_k127_6712899_22 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0001621 46.0
CMS2_k127_6712899_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 321.0
CMS2_k127_6712899_4 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 314.0
CMS2_k127_6712899_5 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001307 278.0
CMS2_k127_6712899_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001188 283.0
CMS2_k127_6712899_7 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004125 235.0
CMS2_k127_6712899_8 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000006735 143.0
CMS2_k127_6712899_9 AI-2E family transporter - - - 0.0000000000000000000000000000004607 123.0
CMS2_k127_6714696_0 Ferrous iron transport protein B K04759 - - 2.234e-246 782.0
CMS2_k127_6714696_1 Highly conserved protein containing a thioredoxin domain K06888 - - 6.164e-240 762.0
CMS2_k127_6714696_2 Adenylate cyclase - - - 4.391e-202 644.0
CMS2_k127_6714696_3 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000002632 249.0
CMS2_k127_6714696_5 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000001274 142.0
CMS2_k127_6714696_6 nUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000001517 141.0
CMS2_k127_6714696_7 - - - - 0.000000000000000005948 93.0
CMS2_k127_6714696_8 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.0000008636 54.0
CMS2_k127_6721923_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 545.0
CMS2_k127_6721923_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 535.0
CMS2_k127_6721923_2 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 433.0
CMS2_k127_6721923_3 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003026 263.0
CMS2_k127_6721923_4 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000508 152.0
CMS2_k127_6721923_5 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000001371 117.0
CMS2_k127_6721923_6 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.0000000000000000000445 93.0
CMS2_k127_6732844_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1431.0
CMS2_k127_6732844_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0 1011.0
CMS2_k127_6732844_10 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 3.747e-213 665.0
CMS2_k127_6732844_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.266e-211 661.0
CMS2_k127_6732844_12 Belongs to the thiolase family K00626 - 2.3.1.9 6.982e-200 628.0
CMS2_k127_6732844_13 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 2.444e-199 625.0
CMS2_k127_6732844_14 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 8.416e-196 615.0
CMS2_k127_6732844_15 two-component sensor kinase K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 614.0
CMS2_k127_6732844_16 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 610.0
CMS2_k127_6732844_17 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 589.0
CMS2_k127_6732844_18 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 565.0
CMS2_k127_6732844_19 associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 538.0
CMS2_k127_6732844_2 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 3.629e-319 989.0
CMS2_k127_6732844_20 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 536.0
CMS2_k127_6732844_21 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 494.0
CMS2_k127_6732844_22 Putative metallopeptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 478.0
CMS2_k127_6732844_23 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 427.0
CMS2_k127_6732844_24 Peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 412.0
CMS2_k127_6732844_25 phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 405.0
CMS2_k127_6732844_26 PFAM response regulator receiver K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 400.0
CMS2_k127_6732844_27 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 383.0
CMS2_k127_6732844_28 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 382.0
CMS2_k127_6732844_29 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 347.0
CMS2_k127_6732844_3 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.049e-296 929.0
CMS2_k127_6732844_30 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 336.0
CMS2_k127_6732844_31 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 337.0
CMS2_k127_6732844_32 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 323.0
CMS2_k127_6732844_33 PFAM Protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 313.0
CMS2_k127_6732844_34 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001394 262.0
CMS2_k127_6732844_35 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000009997 251.0
CMS2_k127_6732844_36 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000474 267.0
CMS2_k127_6732844_37 Rod shape-determining protein mreD K03571 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008764 250.0
CMS2_k127_6732844_38 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002594 231.0
CMS2_k127_6732844_39 Type ii and iii secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000002681 230.0
CMS2_k127_6732844_4 PFAM glucose-methanol-choline oxidoreductase K00108 - 1.1.99.1 4.195e-275 854.0
CMS2_k127_6732844_40 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000005113 218.0
CMS2_k127_6732844_41 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000008967 214.0
CMS2_k127_6732844_42 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.0000000000000000000000000000000000000000000000000000000000009355 219.0
CMS2_k127_6732844_43 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000000000000000000000000000000003585 198.0
CMS2_k127_6732844_44 RNA-binding protein - - - 0.00000000000000000000000000000000000000000000009327 172.0
CMS2_k127_6732844_45 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000347 158.0
CMS2_k127_6732844_46 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000000003844 133.0
CMS2_k127_6732844_47 Pfam Periplasmic binding protein - - - 0.00000000000000000000000000000002421 134.0
CMS2_k127_6732844_48 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000285 138.0
CMS2_k127_6732844_49 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000003905 106.0
CMS2_k127_6732844_5 Acetyl-coenzyme A transporter 1 K08218 - - 1.809e-254 793.0
CMS2_k127_6732844_50 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000006451 85.0
CMS2_k127_6732844_51 - - - - 0.0000000000000003252 87.0
CMS2_k127_6732844_53 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.00000001392 55.0
CMS2_k127_6732844_54 Tetratricopeptide repeat - - - 0.000003581 58.0
CMS2_k127_6732844_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.11e-251 786.0
CMS2_k127_6732844_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 8.17e-251 781.0
CMS2_k127_6732844_8 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.48e-246 767.0
CMS2_k127_6732844_9 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.771e-237 741.0
CMS2_k127_6885184_0 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 524.0
CMS2_k127_6885184_1 membrane-associated Zn-dependent proteases 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 462.0
CMS2_k127_6885184_10 Protein conserved in bacteria - - - 0.000000000000008765 89.0
CMS2_k127_6885184_11 Domain of unknown function (DUF4440) - - - 0.000000000003116 80.0
CMS2_k127_6885184_12 - - - - 0.00000001548 62.0
CMS2_k127_6885184_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 403.0
CMS2_k127_6885184_3 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 333.0
CMS2_k127_6885184_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001996 292.0
CMS2_k127_6885184_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000004408 228.0
CMS2_k127_6885184_6 plastoquinol--plastocyanin reductase activity - - - 0.00000000000000000000000000000000000000000000000000008576 198.0
CMS2_k127_6885184_7 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000000001103 178.0
CMS2_k127_6885184_8 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000288 181.0
CMS2_k127_6885184_9 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000152 150.0
CMS2_k127_6887397_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.0 1176.0
CMS2_k127_6887397_1 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 536.0
CMS2_k127_6887397_10 LTXXQ motif family protein - - - 0.00000000000008652 78.0
CMS2_k127_6887397_11 Protein of unknown function (DUF2933) - - - 0.0000000000002841 74.0
CMS2_k127_6887397_12 cellulose binding - - - 0.0000000001921 69.0
CMS2_k127_6887397_13 YHS domain K17686 - 3.6.3.54 0.00000002536 60.0
CMS2_k127_6887397_14 Protein of unknown function (DUF1573) - - - 0.0005863 49.0
CMS2_k127_6887397_2 Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 297.0
CMS2_k127_6887397_3 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001569 255.0
CMS2_k127_6887397_4 periplasmic protein thiol disulfide K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000006055 241.0
CMS2_k127_6887397_5 - - - - 0.0000000000000000000000000000000000000000000000000000002315 199.0
CMS2_k127_6887397_6 metal-binding protein - - - 0.00000000000000000000000000000000000000005771 156.0
CMS2_k127_6887397_7 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000000000000000000000000006706 149.0
CMS2_k127_6887397_8 - - - - 0.00000000000000000000001041 111.0
CMS2_k127_6887397_9 Short C-terminal domain K08982 - - 0.0000000000000006124 79.0
CMS2_k127_7010786_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1181.0
CMS2_k127_7010786_1 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 0.0 1119.0
CMS2_k127_7010786_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 4.136e-315 967.0
CMS2_k127_7010786_3 Histidine kinase-like ATPases - - - 1.793e-256 811.0
CMS2_k127_7010786_4 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 528.0
CMS2_k127_7010786_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 409.0
CMS2_k127_7010786_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000003206 282.0
CMS2_k127_7010786_7 Histidine kinase K20976 - - 0.000000000000000000000001101 108.0
CMS2_k127_7019619_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K00087 - 1.17.1.4 7.466e-248 797.0
CMS2_k127_7019619_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.667e-201 635.0
CMS2_k127_7019619_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 481.0
CMS2_k127_7019619_3 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000001147 186.0
CMS2_k127_7019619_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000001298 200.0
CMS2_k127_7019619_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000002017 174.0
CMS2_k127_7019619_6 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000001015 62.0
CMS2_k127_7019619_7 Cupin - - - 0.0003696 50.0
CMS2_k127_7048153_0 acetolactate synthase large subunit K01652 - 2.2.1.6 9.053e-291 908.0
CMS2_k127_7048153_1 Tripartite tricarboxylate transporter TctA family K07793 - - 1.163e-263 818.0
CMS2_k127_7048153_10 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 548.0
CMS2_k127_7048153_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 520.0
CMS2_k127_7048153_12 Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 511.0
CMS2_k127_7048153_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 469.0
CMS2_k127_7048153_14 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 456.0
CMS2_k127_7048153_15 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 454.0
CMS2_k127_7048153_16 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 462.0
CMS2_k127_7048153_17 shikimate dehydrogenase K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 431.0
CMS2_k127_7048153_18 Xylose isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 432.0
CMS2_k127_7048153_19 mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 425.0
CMS2_k127_7048153_2 Aldehyde dehydrogenase family K04072,K13922 - 1.1.1.1,1.2.1.10,1.2.1.87 1.606e-245 764.0
CMS2_k127_7048153_20 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 421.0
CMS2_k127_7048153_21 ABC transporter ATP-binding protein K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 427.0
CMS2_k127_7048153_22 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 400.0
CMS2_k127_7048153_23 abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 393.0
CMS2_k127_7048153_24 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 392.0
CMS2_k127_7048153_25 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 384.0
CMS2_k127_7048153_26 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 369.0
CMS2_k127_7048153_27 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 352.0
CMS2_k127_7048153_28 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 335.0
CMS2_k127_7048153_29 Short-chain dehydrogenase reductase (SDR) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000441 287.0
CMS2_k127_7048153_3 type II secretion system protein E K02454 - - 1.85e-241 752.0
CMS2_k127_7048153_30 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003642 259.0
CMS2_k127_7048153_31 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000008854 257.0
CMS2_k127_7048153_32 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000024 241.0
CMS2_k127_7048153_33 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000001293 223.0
CMS2_k127_7048153_34 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000000000000000001003 207.0
CMS2_k127_7048153_35 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000001989 193.0
CMS2_k127_7048153_36 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.0000000000000000000000000000000000000000000000000001668 191.0
CMS2_k127_7048153_37 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000000000000000000005908 182.0
CMS2_k127_7048153_38 Type II secretion system protein B K02451 - - 0.0000000000000000000000000000000000002699 151.0
CMS2_k127_7048153_39 - - - - 0.000000000000000000000000000000000006867 145.0
CMS2_k127_7048153_4 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697,K03692 - 2.4.1.15,2.4.1.213,2.4.1.347 2.83e-216 689.0
CMS2_k127_7048153_40 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000008722 124.0
CMS2_k127_7048153_41 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000005188 92.0
CMS2_k127_7048153_42 citrate synthase K01647 - 2.3.3.1 0.000000000000000001015 98.0
CMS2_k127_7048153_43 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000003007 78.0
CMS2_k127_7048153_44 Acetolactate synthase K01577,K01652,K03852 - 2.2.1.6,2.3.3.15,4.1.1.8 0.00000002857 66.0
CMS2_k127_7048153_45 acyl-CoA transferases carnitine dehydratase - - - 0.0006291 42.0
CMS2_k127_7048153_5 CoA-transferase family III - - - 1.14e-207 655.0
CMS2_k127_7048153_6 Acyl-CoA dehydrogenase, type 2, C-terminal domain K00249,K07545 - 1.3.8.3,1.3.8.7 2.499e-206 648.0
CMS2_k127_7048153_7 Aldehyde dehydrogenase family K14519 - 1.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 611.0
CMS2_k127_7048153_8 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 596.0
CMS2_k127_7048153_9 Type II secretory pathway, component ExeA K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008772 593.0
CMS2_k127_730930_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1685.0
CMS2_k127_730930_1 Adenylate and Guanylate cyclase catalytic domain - - - 0.0 1054.0
CMS2_k127_730930_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 587.0
CMS2_k127_730930_11 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 522.0
CMS2_k127_730930_12 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 494.0
CMS2_k127_730930_13 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 408.0
CMS2_k127_730930_14 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008465 372.0
CMS2_k127_730930_15 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 324.0
CMS2_k127_730930_16 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002464 273.0
CMS2_k127_730930_17 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005085 231.0
CMS2_k127_730930_18 Protein of unknown function (DUF2652) - - - 0.00000000000000000000000000000000000000000000000000000000000000004182 239.0
CMS2_k127_730930_19 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000008178 216.0
CMS2_k127_730930_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.454e-248 782.0
CMS2_k127_730930_20 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000004157 211.0
CMS2_k127_730930_21 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000005951 199.0
CMS2_k127_730930_22 GYD domain - - - 0.000000000000234 83.0
CMS2_k127_730930_23 PFAM amidohydrolase K01464,K01466 - 3.5.2.2,3.5.2.5 0.00000000009947 63.0
CMS2_k127_730930_24 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.0006811 46.0
CMS2_k127_730930_3 ABC transporter transmembrane region K02021 - - 1.372e-243 781.0
CMS2_k127_730930_4 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 2.454e-242 765.0
CMS2_k127_730930_5 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 5.247e-241 779.0
CMS2_k127_730930_6 ABC transporter transmembrane region K18889 - - 1.413e-239 755.0
CMS2_k127_730930_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.435e-226 708.0
CMS2_k127_730930_8 ABC transporter transmembrane region K18890 - - 3.818e-225 726.0
CMS2_k127_730930_9 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 589.0
CMS2_k127_782113_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.321e-274 850.0
CMS2_k127_782113_1 Arm DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 518.0
CMS2_k127_782113_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 467.0
CMS2_k127_782113_3 Psort location Cytoplasmic, score 8.96 K01783 - 5.1.3.1 0.000000000000002751 75.0
CMS2_k127_788773_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 4.528e-240 777.0
CMS2_k127_788773_1 N-methylhydantoinase B acetone carboxylase alpha subunit - - - 2.206e-233 734.0
CMS2_k127_788773_10 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000154 49.0
CMS2_k127_788773_2 CoA binding domain - - - 2.922e-209 672.0
CMS2_k127_788773_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 570.0
CMS2_k127_788773_4 UPF0365 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 490.0
CMS2_k127_788773_5 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 448.0
CMS2_k127_788773_6 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 436.0
CMS2_k127_788773_7 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.0000000000000000000000000000000000000000000000002027 179.0
CMS2_k127_788773_8 SnoaL-like polyketide cyclase K07255 - - 0.00000000000000000000000000000000000006023 147.0
CMS2_k127_788773_9 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000003812 96.0
CMS2_k127_794602_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1713.0
CMS2_k127_794602_1 FAD binding domain K00394 - 1.8.99.2 0.0 1237.0
CMS2_k127_794602_10 4Fe-4S binding domain K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 456.0
CMS2_k127_794602_11 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 456.0
CMS2_k127_794602_12 DMSO reductase anchor subunit (DmsC) K21309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 433.0
CMS2_k127_794602_13 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 368.0
CMS2_k127_794602_14 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 341.0
CMS2_k127_794602_15 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 308.0
CMS2_k127_794602_16 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 299.0
CMS2_k127_794602_17 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 292.0
CMS2_k127_794602_18 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000002152 224.0
CMS2_k127_794602_19 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000003696 167.0
CMS2_k127_794602_2 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1088.0
CMS2_k127_794602_20 PFAM Cytochrome C K17230 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000002917 167.0
CMS2_k127_794602_3 Sulfate transporter antisigma-factor antagonist STAS - - - 1.95e-264 836.0
CMS2_k127_794602_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.247e-232 736.0
CMS2_k127_794602_5 Sulfate permease family K03321 - - 2.184e-231 736.0
CMS2_k127_794602_6 PUA-like domain K00958 - 2.7.7.4 2.973e-205 644.0
CMS2_k127_794602_7 HI0933-like protein - - - 1.512e-194 616.0
CMS2_k127_794602_8 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 554.0
CMS2_k127_794602_9 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 549.0
CMS2_k127_89514_0 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 1.359e-238 748.0
CMS2_k127_89514_1 protein conserved in bacteria - - - 9.545e-198 636.0
CMS2_k127_89514_10 Glutamine amidotransferases class-II - - - 0.000000000000000000000001559 104.0
CMS2_k127_89514_11 Glutamine amidotransferases class-II - - - 0.00000000000000000000006114 102.0
CMS2_k127_89514_2 Diguanylate cyclase - - - 6.131e-196 635.0
CMS2_k127_89514_3 C4-dicarboxylate transporter malic acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 424.0
CMS2_k127_89514_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 362.0
CMS2_k127_89514_5 Amino-transferase class IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 349.0
CMS2_k127_89514_6 Protein of unknown function (DUF2953) - - - 0.000000000000000000000000000000000000000000000000000000000000001815 223.0
CMS2_k127_89514_7 Protein of unknown function, DUF481 K07283 - - 0.000000000000000000000000000000000000000000000000000004306 205.0
CMS2_k127_89514_8 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000001071 196.0
CMS2_k127_89514_9 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.000000000000000000000000000000000000000000009043 167.0
CMS2_k127_971335_0 PFAM NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.0 1170.0
CMS2_k127_971335_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.175e-298 926.0
CMS2_k127_971335_10 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 530.0
CMS2_k127_971335_11 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 509.0
CMS2_k127_971335_12 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 493.0
CMS2_k127_971335_13 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 486.0
CMS2_k127_971335_14 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 447.0
CMS2_k127_971335_15 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 413.0
CMS2_k127_971335_16 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 390.0
CMS2_k127_971335_17 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 339.0
CMS2_k127_971335_18 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 334.0
CMS2_k127_971335_19 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 345.0
CMS2_k127_971335_2 Superfamily I DNA and RNA helicases K03657 - 3.6.4.12 2.622e-273 858.0
CMS2_k127_971335_20 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 323.0
CMS2_k127_971335_21 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 357.0
CMS2_k127_971335_22 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 305.0
CMS2_k127_971335_23 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 295.0
CMS2_k127_971335_24 Transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001337 236.0
CMS2_k127_971335_25 Trap-type c4-dicarboxylate transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000002067 201.0
CMS2_k127_971335_3 2-aminobenzoate-CoA ligase K08295 - 6.2.1.32 3.655e-245 767.0
CMS2_k127_971335_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 2.015e-229 721.0
CMS2_k127_971335_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.524e-213 687.0
CMS2_k127_971335_6 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 1.627e-208 654.0
CMS2_k127_971335_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00457 - 1.13.11.27 5.201e-208 660.0
CMS2_k127_971335_8 Phosphoesterase family - - - 5.192e-203 642.0
CMS2_k127_971335_9 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 593.0