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Overview

ID MAG00474
Name CMS2_bin.89
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Campylobacterota
Class Campylobacteria
Order Campylobacterales
Family Sulfurimonadaceae
Genus GCA-2733885
Species
Assembly information
Completeness (%) 72.58
Contamination (%) 0.73
GC content (%) 46.0
N50 (bp) 11,711
Genome size (bp) 1,541,038

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1524

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1043596_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 4.216e-199 626.0
CMS2_k127_1043596_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 440.0
CMS2_k127_1043596_2 DNA replication regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002535 265.0
CMS2_k127_1043596_3 dihydropteroate synthase K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000001263 265.0
CMS2_k127_1043596_4 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000002984 232.0
CMS2_k127_1043596_5 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000001265 180.0
CMS2_k127_1043596_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000002736 122.0
CMS2_k127_1043596_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000007043 57.0
CMS2_k127_1113982_0 ATP synthase K02412 - 3.6.3.14 3.057e-213 668.0
CMS2_k127_1113982_1 Cysteine desulfurase K04487 - 2.8.1.7 1.384e-210 659.0
CMS2_k127_1113982_10 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 428.0
CMS2_k127_1113982_11 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 333.0
CMS2_k127_1113982_12 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 332.0
CMS2_k127_1113982_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000001839 239.0
CMS2_k127_1113982_14 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000003094 213.0
CMS2_k127_1113982_16 Protein of unknown function (DUF3313) - - - 0.000003565 57.0
CMS2_k127_1113982_2 Mg chelatase-related protein K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 615.0
CMS2_k127_1113982_3 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 582.0
CMS2_k127_1113982_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 571.0
CMS2_k127_1113982_5 Belongs to the UPF0324 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 556.0
CMS2_k127_1113982_6 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 495.0
CMS2_k127_1113982_7 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 489.0
CMS2_k127_1113982_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 476.0
CMS2_k127_1113982_9 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 468.0
CMS2_k127_1115418_0 PFAM TonB-dependent Receptor Plug Domain K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 436.0
CMS2_k127_1115418_1 Pas domain K13590 - 2.7.7.65 0.0000000000000000000000000000000001857 136.0
CMS2_k127_1115418_2 - - - - 0.00000000000000000002356 98.0
CMS2_k127_1115418_3 Putative diguanylate phosphodiesterase - - - 0.000000000000000000206 97.0
CMS2_k127_1139580_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1253.0
CMS2_k127_1139580_1 ABC transporter, ATP-binding protein K13926 - - 2.891e-225 709.0
CMS2_k127_1139580_10 - - - - 0.00000000000000000000000000000000000000000003576 163.0
CMS2_k127_1139580_11 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000001189 109.0
CMS2_k127_1139580_12 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000001761 68.0
CMS2_k127_1139580_2 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 478.0
CMS2_k127_1139580_3 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 467.0
CMS2_k127_1139580_4 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 441.0
CMS2_k127_1139580_5 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 394.0
CMS2_k127_1139580_6 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 378.0
CMS2_k127_1139580_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 355.0
CMS2_k127_1139580_8 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006439 266.0
CMS2_k127_1139580_9 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000001063 232.0
CMS2_k127_1140394_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.576e-291 904.0
CMS2_k127_1140394_1 flagellar motor switch protein K02410 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 522.0
CMS2_k127_1140394_2 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 352.0
CMS2_k127_1140394_3 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000008958 266.0
CMS2_k127_1140394_4 flagellar assembly protein FliH K02411 - - 0.00000000000000000000000000000000000000000000000000000000006223 213.0
CMS2_k127_1140394_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000121 205.0
CMS2_k127_1140394_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000004583 186.0
CMS2_k127_1140394_7 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000001664 148.0
CMS2_k127_1140394_8 DnaJ domain protein K05801 - - 0.00005545 54.0
CMS2_k127_1206005_0 Abc transporter K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 338.0
CMS2_k127_1206005_1 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 324.0
CMS2_k127_1206005_2 Methyltransferase domain K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000001504 259.0
CMS2_k127_1206005_3 thiamine-phosphate diphosphorylase activity K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000001085 186.0
CMS2_k127_1206005_4 Belongs to the BI1 family K19416 - - 0.00000000000001342 73.0
CMS2_k127_1226383_0 peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 556.0
CMS2_k127_1226383_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 489.0
CMS2_k127_1226383_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 448.0
CMS2_k127_1226383_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 419.0
CMS2_k127_1226383_4 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004884 281.0
CMS2_k127_1226383_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000009127 261.0
CMS2_k127_1226383_6 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000555 132.0
CMS2_k127_1265475_0 COG0841 Cation multidrug efflux pump - - - 1.023e-259 811.0
CMS2_k127_1265475_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 4.704e-259 806.0
CMS2_k127_1265475_2 Hpt sensor hybrid histidine kinase - - - 4.728e-252 805.0
CMS2_k127_1265475_3 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 473.0
CMS2_k127_1265475_4 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 358.0
CMS2_k127_1265475_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 347.0
CMS2_k127_1265475_6 Stress responsive A B Barrel Domain - - - 0.0000000000000000000000000000002704 126.0
CMS2_k127_1265475_7 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000000000000003086 115.0
CMS2_k127_1265475_8 Protein of unknown function (DUF2892) - - - 0.0000000001914 63.0
CMS2_k127_1265475_9 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000003018 58.0
CMS2_k127_1306718_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.292e-283 889.0
CMS2_k127_1306718_1 Sulfite dehydrogenase (Cytochrome) subunit SorA apoprotein K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 595.0
CMS2_k127_1306718_10 Transcriptional regulator, LysR family - - - 0.0000000000000000007326 90.0
CMS2_k127_1306718_2 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 539.0
CMS2_k127_1306718_3 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 471.0
CMS2_k127_1306718_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 420.0
CMS2_k127_1306718_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 289.0
CMS2_k127_1306718_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000144 235.0
CMS2_k127_1306718_7 Ferredoxin K05337 - - 0.000000000000000000000000000000000000000001127 157.0
CMS2_k127_1306718_8 cytochrome C oxidoreductase subunit B - - - 0.0000000000000000000000000000000000000009722 149.0
CMS2_k127_1306718_9 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000001495 112.0
CMS2_k127_1348450_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 286.0
CMS2_k127_1348450_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005404 278.0
CMS2_k127_1348450_2 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000001781 185.0
CMS2_k127_1371020_0 Belongs to the peptidase M16 family - - - 3.916e-203 640.0
CMS2_k127_1371020_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 3.808e-202 638.0
CMS2_k127_1371020_10 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 319.0
CMS2_k127_1371020_11 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 329.0
CMS2_k127_1371020_12 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 301.0
CMS2_k127_1371020_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001478 266.0
CMS2_k127_1371020_14 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001157 276.0
CMS2_k127_1371020_15 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000033 222.0
CMS2_k127_1371020_16 -acetyltransferase K06975 - - 0.0000000000000000000000000000236 119.0
CMS2_k127_1371020_17 DNA-binding protein VF530 - - - 0.00000000000000000000000000305 111.0
CMS2_k127_1371020_18 Rhodanese Homology Domain - - - 0.000000000000000000000002979 105.0
CMS2_k127_1371020_19 - - - - 0.0001777 46.0
CMS2_k127_1371020_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 535.0
CMS2_k127_1371020_3 Flagellar Assembly Protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 546.0
CMS2_k127_1371020_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 522.0
CMS2_k127_1371020_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 489.0
CMS2_k127_1371020_6 dehydrogenase K00076 - 1.1.1.159 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 461.0
CMS2_k127_1371020_7 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 462.0
CMS2_k127_1371020_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 441.0
CMS2_k127_1371020_9 Mur ligase middle domain K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 428.0
CMS2_k127_1371853_0 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 1.278e-232 733.0
CMS2_k127_1371853_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 557.0
CMS2_k127_1371853_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 396.0
CMS2_k127_1371853_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 379.0
CMS2_k127_1371853_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 314.0
CMS2_k127_1371853_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 312.0
CMS2_k127_1371853_6 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000000000000000000000000000001266 203.0
CMS2_k127_1371853_7 esterase K07000 GO:0003674,GO:0003824,GO:0016787,GO:0016788 - 0.0000000000000000002128 96.0
CMS2_k127_1371853_9 Antibiotic biosynthesis monooxygenase - - - 0.0000003738 56.0
CMS2_k127_1398186_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1424.0
CMS2_k127_1398186_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 7.819e-268 827.0
CMS2_k127_1398186_2 Belongs to the pseudouridine synthase RluA family K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 333.0
CMS2_k127_1398186_3 GTP-binding protein K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001836 255.0
CMS2_k127_1398186_4 - - - - 0.00000000000000000000006806 102.0
CMS2_k127_140115_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1129.0
CMS2_k127_140115_1 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 582.0
CMS2_k127_140115_10 DnaJ domain protein K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 295.0
CMS2_k127_140115_11 Double sensory domain of two-component sensor kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005939 289.0
CMS2_k127_140115_12 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000002027 124.0
CMS2_k127_140115_14 deoxyribonuclease I activity K01150 - 3.1.21.1 0.0000000000000000000004335 105.0
CMS2_k127_140115_15 EF hand - - - 0.000000000005396 69.0
CMS2_k127_140115_16 EF hand - - - 0.0000003344 55.0
CMS2_k127_140115_2 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 507.0
CMS2_k127_140115_3 Protein of unknown function (DUF3050) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 460.0
CMS2_k127_140115_4 Hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 456.0
CMS2_k127_140115_5 Protein of unknown function (DUF808) K09781 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 387.0
CMS2_k127_140115_6 S1 domain K00243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 331.0
CMS2_k127_140115_7 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 328.0
CMS2_k127_140115_8 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 313.0
CMS2_k127_140115_9 PFAM Archaea bacterial proteins of K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 306.0
CMS2_k127_1487174_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 7.617e-306 941.0
CMS2_k127_1487174_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 376.0
CMS2_k127_1487174_2 AsmA-like C-terminal region K07289 - - 0.000000000000000000000000000000000000000004035 177.0
CMS2_k127_1541451_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367,K00372,K08356 - 1.20.2.1,1.20.9.1,1.7.7.2 0.0 1070.0
CMS2_k127_1541451_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K15576 - - 3.444e-266 823.0
CMS2_k127_1541451_2 COG0155 Sulfite reductase, beta subunit (hemoprotein) K00366,K00392 - 1.7.7.1,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 548.0
CMS2_k127_1541451_3 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 505.0
CMS2_k127_1541451_4 ABC transporter K15555,K15578 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 458.0
CMS2_k127_1541451_5 COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 437.0
CMS2_k127_1541451_6 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 396.0
CMS2_k127_1541451_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 361.0
CMS2_k127_1568319_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1310.0
CMS2_k127_1568319_1 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 3.079e-248 771.0
CMS2_k127_1568319_2 Malate quinone- oxidoreductase K00116 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.5.4 1.819e-244 762.0
CMS2_k127_1568319_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.517e-241 751.0
CMS2_k127_1568319_4 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000006399 232.0
CMS2_k127_1568319_5 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000000000000000000000000000000000000000000000000008675 215.0
CMS2_k127_1568319_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000003273 177.0
CMS2_k127_1568319_7 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000009536 136.0
CMS2_k127_1578572_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1005.0
CMS2_k127_1578572_1 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 4.73e-225 712.0
CMS2_k127_1578572_10 Phospholipase/Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 284.0
CMS2_k127_1578572_11 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000353 273.0
CMS2_k127_1578572_12 protein conserved in bacteria K09859 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002242 271.0
CMS2_k127_1578572_13 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.00000000000000000000000000000000000000000000000000000000000000000003884 237.0
CMS2_k127_1578572_14 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000004505 211.0
CMS2_k127_1578572_15 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000002115 190.0
CMS2_k127_1578572_16 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000000006696 184.0
CMS2_k127_1578572_17 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000001529 133.0
CMS2_k127_1578572_18 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000001105 121.0
CMS2_k127_1578572_19 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000001201 124.0
CMS2_k127_1578572_2 Fad-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 550.0
CMS2_k127_1578572_20 endonuclease containing a URI domain K07461 - - 0.00000000000000000000000000004154 118.0
CMS2_k127_1578572_21 - - - - 0.000000000000000000000000003175 115.0
CMS2_k127_1578572_22 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000009922 68.0
CMS2_k127_1578572_23 Protein of unknown function (DUF1425) - - - 0.000000005892 62.0
CMS2_k127_1578572_24 AF0941-like - - - 0.000003562 53.0
CMS2_k127_1578572_3 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 537.0
CMS2_k127_1578572_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 511.0
CMS2_k127_1578572_5 lytic murein transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 496.0
CMS2_k127_1578572_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 405.0
CMS2_k127_1578572_7 hydrolase, TatD K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 354.0
CMS2_k127_1578572_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 304.0
CMS2_k127_1578572_9 Imidazoleglycerol-phosphate dehydratase K01089,K01693 - 3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 299.0
CMS2_k127_159508_0 COG0659 Sulfate permease and related K03321 - - 5.311e-232 727.0
CMS2_k127_159508_1 PFAM HI0933 family protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 468.0
CMS2_k127_159508_10 Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000005179 169.0
CMS2_k127_159508_11 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000255 90.0
CMS2_k127_159508_12 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000003735 58.0
CMS2_k127_159508_2 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 436.0
CMS2_k127_159508_3 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 414.0
CMS2_k127_159508_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 377.0
CMS2_k127_159508_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 344.0
CMS2_k127_159508_6 Transglutaminase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 337.0
CMS2_k127_159508_7 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 312.0
CMS2_k127_159508_8 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 300.0
CMS2_k127_159508_9 GatB Yqey family protein K09117 - - 0.000000000000000000000000000000000000000000000000001243 186.0
CMS2_k127_1614403_0 growth of symbiont in host cell K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 601.0
CMS2_k127_1614403_1 dna polymerase iii K10857 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 364.0
CMS2_k127_1614403_3 Rhodanese-like domain - - - 0.0000000000000000000000000000000001359 138.0
CMS2_k127_1614403_5 - - - - 0.0000000000000000000000000001168 120.0
CMS2_k127_1614403_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000000008829 110.0
CMS2_k127_1614403_7 Translation initiation factor SUI1 K03113 - - 0.0000000000000008756 78.0
CMS2_k127_1737875_0 GAF domain K01768 - 4.6.1.1 0.0 2121.0
CMS2_k127_1737875_1 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 6.286e-225 706.0
CMS2_k127_1737875_2 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 615.0
CMS2_k127_1737875_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 333.0
CMS2_k127_1737875_4 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007447 261.0
CMS2_k127_183954_0 Belongs to the DEAD box helicase family K05592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 500.0
CMS2_k127_183954_1 DNA recombination protein K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 429.0
CMS2_k127_183954_2 Cache domain K02480,K03406 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 402.0
CMS2_k127_183954_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 321.0
CMS2_k127_183954_4 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 312.0
CMS2_k127_183954_5 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000008301 218.0
CMS2_k127_183954_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000005948 208.0
CMS2_k127_183954_7 Histidine kinase K07645 - 2.7.13.3 0.000000000000000000000000000000000000001046 163.0
CMS2_k127_183954_8 - - - - 0.0000000000003259 71.0
CMS2_k127_1869507_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 533.0
CMS2_k127_2040218_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.886e-210 665.0
CMS2_k127_2040218_1 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 434.0
CMS2_k127_2040218_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009947 411.0
CMS2_k127_2040218_3 cation diffusion facilitator family transporter K13283 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005385,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006829,GO:0006873,GO:0006875,GO:0006876,GO:0006882,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015086,GO:0015093,GO:0015291,GO:0015318,GO:0015341,GO:0015562,GO:0015684,GO:0015691,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0030003,GO:0034220,GO:0034755,GO:0042592,GO:0042802,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055069,GO:0055073,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070574,GO:0070838,GO:0071577,GO:0071944,GO:0072503,GO:0072507,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:1903874 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 342.0
CMS2_k127_2040218_4 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000001409 179.0
CMS2_k127_2040218_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000002393 175.0
CMS2_k127_2040218_6 thioesterase K02614 - - 0.000000000000000000000000000000000000001799 151.0
CMS2_k127_2040218_7 Cytochrome c family protein - - - 0.00000000000000000000000000000000000004201 150.0
CMS2_k127_2040218_8 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000001441 94.0
CMS2_k127_2043333_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2276.0
CMS2_k127_2043333_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 1.781e-237 740.0
CMS2_k127_2043333_10 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000001346 254.0
CMS2_k127_2043333_11 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000003454 239.0
CMS2_k127_2043333_12 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000005886 202.0
CMS2_k127_2043333_13 DnaK suppressor protein K06204 - - 0.000000000000000000000000000000000000000000003706 166.0
CMS2_k127_2043333_14 Transcriptional regulator - - - 0.00000000000000000000000000000000000006684 145.0
CMS2_k127_2043333_15 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000001165 123.0
CMS2_k127_2043333_16 - - - - 0.0000000000000000000000002523 114.0
CMS2_k127_2043333_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 508.0
CMS2_k127_2043333_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 447.0
CMS2_k127_2043333_4 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 424.0
CMS2_k127_2043333_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 336.0
CMS2_k127_2043333_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 324.0
CMS2_k127_2043333_7 RecO N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001802 275.0
CMS2_k127_2043333_8 PhnA Zinc-Ribbon K06193 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002924 269.0
CMS2_k127_2043333_9 Hemolysin K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000002894 266.0
CMS2_k127_2066754_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.087e-223 698.0
CMS2_k127_2066754_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000115 265.0
CMS2_k127_2066754_2 - - - - 0.0000000000000000000000000000000001535 138.0
CMS2_k127_2066754_3 RNA-binding protein homologous to eukaryotic snRNP - - - 0.0000000000000000000000000000001634 127.0
CMS2_k127_2066754_4 Belongs to the UPF0250 family - - - 0.000000000000000000000000000002805 122.0
CMS2_k127_2074506_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 575.0
CMS2_k127_2074506_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 492.0
CMS2_k127_2074506_2 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 419.0
CMS2_k127_2074506_3 cation efflux system protein K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 393.0
CMS2_k127_2074506_4 Receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 320.0
CMS2_k127_2074506_5 YtkA-like - - - 0.00000000000000000000000000000002542 130.0
CMS2_k127_2074506_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0002274 44.0
CMS2_k127_2079967_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 252.0
CMS2_k127_2079967_10 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000002015 117.0
CMS2_k127_2079967_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006333 226.0
CMS2_k127_2079967_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000005632 213.0
CMS2_k127_2079967_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000544 211.0
CMS2_k127_2079967_5 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000000000000000007359 210.0
CMS2_k127_2079967_6 - - - - 0.000000000000000000000000000000000000000000000002687 178.0
CMS2_k127_2079967_8 Dinitrogenase iron-molybdenum cofactor biosynthesis protein K02596 - - 0.00000000000000000000000000000000000001723 147.0
CMS2_k127_2079967_9 molybdate ion transport K02017,K06857 - 3.6.3.29,3.6.3.55 0.000000000000000000000001736 108.0
CMS2_k127_2087799_0 GMC oxidoreductase K06151 - 1.1.99.3 1.178e-205 651.0
CMS2_k127_2087799_1 K -dependent Na Ca exchanger K07301 - - 0.0000000000000000000000000000000000000000000000000001793 186.0
CMS2_k127_2087799_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000001125 177.0
CMS2_k127_2087799_3 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000003431 123.0
CMS2_k127_2113273_0 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 429.0
CMS2_k127_2113273_1 Outer membrane protein beta-barrel family K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 332.0
CMS2_k127_2113273_2 Bacterial periplasmic substrate-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000006523 249.0
CMS2_k127_2113273_3 diguanylate cyclase K21019 - 2.7.7.65 0.00000000000000000000000000000000000000000000003136 186.0
CMS2_k127_2113273_5 Protein of unknown function (DUF3050) - - - 0.000005769 48.0
CMS2_k127_2130622_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 536.0
CMS2_k127_2130622_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 341.0
CMS2_k127_2155118_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 572.0
CMS2_k127_2155118_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 378.0
CMS2_k127_2155118_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 349.0
CMS2_k127_2155118_3 tigr02757 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 307.0
CMS2_k127_2155118_4 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000001845 196.0
CMS2_k127_2155118_5 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000001474 138.0
CMS2_k127_2157668_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 4.249e-259 818.0
CMS2_k127_2157668_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 9.66e-202 635.0
CMS2_k127_2157668_10 cytochrome - - - 0.00000000000000002468 90.0
CMS2_k127_2157668_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000001 64.0
CMS2_k127_2157668_12 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.000000784 53.0
CMS2_k127_2157668_2 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 537.0
CMS2_k127_2157668_3 7TM diverse intracellular signalling K20971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 504.0
CMS2_k127_2157668_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 443.0
CMS2_k127_2157668_5 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 361.0
CMS2_k127_2157668_6 hydrolase K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 341.0
CMS2_k127_2157668_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000007973 178.0
CMS2_k127_2157668_8 - - - - 0.0000000000000000000000000003869 122.0
CMS2_k127_2169840_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 4.904e-194 623.0
CMS2_k127_2169840_1 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 378.0
CMS2_k127_2169840_2 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 327.0
CMS2_k127_2169840_3 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 327.0
CMS2_k127_2169840_4 dehydrogenase K08325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 308.0
CMS2_k127_2281362_0 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K03581 - 3.1.11.5 3.834e-276 868.0
CMS2_k127_2281362_1 Diguanylate cyclase (GGDEF domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 454.0
CMS2_k127_2281362_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 372.0
CMS2_k127_2281362_3 COGs COG3786 conserved - - - 0.000000000000000000000000000000000000000000000000001358 191.0
CMS2_k127_229700_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.531e-308 956.0
CMS2_k127_229700_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 5.544e-235 750.0
CMS2_k127_229700_10 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000003301 113.0
CMS2_k127_229700_2 COG0457 FOG TPR repeat - - - 3.158e-224 718.0
CMS2_k127_229700_3 permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 501.0
CMS2_k127_229700_4 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 332.0
CMS2_k127_229700_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002349 274.0
CMS2_k127_229700_6 Chemotaxis protein cheY K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000007826 231.0
CMS2_k127_229700_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000001598 169.0
CMS2_k127_229700_8 Uncharacterised signal transduction histidine kinase domain (DUF2222) - - - 0.00000000000000000000000000000000000003836 160.0
CMS2_k127_229700_9 Redox-active disulfide protein - - - 0.0000000000000000000000000000000004437 131.0
CMS2_k127_2333960_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 533.0
CMS2_k127_2333960_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 474.0
CMS2_k127_2333960_2 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006477 238.0
CMS2_k127_2333960_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000002282 207.0
CMS2_k127_2333960_4 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000008671 158.0
CMS2_k127_2333960_5 Evidence 4 Homologs of previously reported genes of K21440 - - 0.0000000000000000000000000000000000005285 149.0
CMS2_k127_2333960_6 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.0000000000000000000000000000004831 124.0
CMS2_k127_2333960_7 Rhodanese Homology Domain - - - 0.00000000000000000000001505 105.0
CMS2_k127_2360408_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.352e-241 762.0
CMS2_k127_2360408_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 514.0
CMS2_k127_2360408_10 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000005761 130.0
CMS2_k127_2360408_2 Histidine kinase A domain protein K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 399.0
CMS2_k127_2360408_3 dna polymerase iii K10857 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 364.0
CMS2_k127_2360408_4 leucine binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 369.0
CMS2_k127_2360408_5 COGs COG0665 Glycine D-amino acid oxidase (deaminating) K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 329.0
CMS2_k127_2360408_6 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000009317 231.0
CMS2_k127_2360408_7 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000000000009271 223.0
CMS2_k127_2360408_8 alpha beta K06889 - - 0.00000000000000000000000000000000000002027 154.0
CMS2_k127_2360408_9 thioesterase K07107 - - 0.0000000000000000000000000000000000001805 144.0
CMS2_k127_2360510_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 1.582e-226 705.0
CMS2_k127_2360510_1 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 4.826e-194 610.0
CMS2_k127_2360510_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 604.0
CMS2_k127_2360510_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000003761 235.0
CMS2_k127_2360510_4 Histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000001311 244.0
CMS2_k127_2360510_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005421 229.0
CMS2_k127_2360510_6 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000004394 206.0
CMS2_k127_2360510_7 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000004776 153.0
CMS2_k127_2360510_8 helicase activity - - - 0.0000000000000000000000000000004638 131.0
CMS2_k127_2360510_9 VIT family - - - 0.0000000000000000000001068 98.0
CMS2_k127_2364170_0 COG0841 Cation multidrug efflux pump - - - 2.456e-261 816.0
CMS2_k127_2364170_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 539.0
CMS2_k127_2364170_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005395 229.0
CMS2_k127_2364170_3 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0000000000000000000000000000000002997 133.0
CMS2_k127_239386_0 transporter - - - 2.295e-194 614.0
CMS2_k127_239386_1 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 573.0
CMS2_k127_239386_10 molybdopterin converting factor K03636 - - 0.000000000000000000000000003364 111.0
CMS2_k127_239386_11 diguanylate cyclase - - - 0.00000000000000000000006801 108.0
CMS2_k127_239386_12 diguanylate cyclase K13590 - 2.7.7.65 0.0000000000000000001702 98.0
CMS2_k127_239386_2 molybdopterin biosynthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 487.0
CMS2_k127_239386_3 PFAM tRNA synthetase class II (G H P and S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 358.0
CMS2_k127_239386_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 297.0
CMS2_k127_239386_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006047 271.0
CMS2_k127_239386_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000002133 258.0
CMS2_k127_239386_7 molybdopterin converting factor K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000002766 239.0
CMS2_k127_239386_8 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000005329 209.0
CMS2_k127_239386_9 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000000009464 187.0
CMS2_k127_2457666_0 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 489.0
CMS2_k127_2457666_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 445.0
CMS2_k127_2457666_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 381.0
CMS2_k127_2457666_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 344.0
CMS2_k127_2457666_4 hmm pf04305 - - - 0.00000000000000000000000000000000000000000000000000004623 190.0
CMS2_k127_2457666_5 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000614 109.0
CMS2_k127_2478451_0 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 602.0
CMS2_k127_2478451_1 Pseudouridine synthase K06177,K06179,K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 325.0
CMS2_k127_2478451_10 Prokaryotic metallothionein K06950 - - 0.00000000005474 72.0
CMS2_k127_2478451_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 319.0
CMS2_k127_2478451_3 synthase K06175 - 5.4.99.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 301.0
CMS2_k127_2478451_4 G T U mismatch-specific DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000287 236.0
CMS2_k127_2478451_5 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.00000000000000000000000000000000000000000000000001127 183.0
CMS2_k127_2478451_6 NlpC/P60 family K13695,K19303 - - 0.00000000000000000000000000000000000000004715 158.0
CMS2_k127_2478451_8 - - - - 0.000000000000000000000000000000001565 133.0
CMS2_k127_2478451_9 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775,K20707 - 5.1.1.1,5.1.1.5 0.00000000000000000000000005533 116.0
CMS2_k127_2513566_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 557.0
CMS2_k127_2513566_1 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000000003595 173.0
CMS2_k127_2513566_2 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000000003879 164.0
CMS2_k127_2513566_3 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000003577 60.0
CMS2_k127_2513566_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000009054 53.0
CMS2_k127_2518841_0 chemotaxis protein K03407 - 2.7.13.3 5.157e-241 768.0
CMS2_k127_2518841_1 alanine symporter K03310 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 581.0
CMS2_k127_2518841_10 protein conserved in bacteria K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000002607 234.0
CMS2_k127_2518841_11 Methylenetetrahydrofolate reductase - - - 0.000000000002069 66.0
CMS2_k127_2518841_12 transmembrane signaling receptor activity K03406 - - 0.00000008725 63.0
CMS2_k127_2518841_2 chemotaxis protein K03415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 477.0
CMS2_k127_2518841_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 464.0
CMS2_k127_2518841_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 380.0
CMS2_k127_2518841_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 360.0
CMS2_k127_2518841_6 involved in molybdopterin and thiamine biosynthesis family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 308.0
CMS2_k127_2518841_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002474 254.0
CMS2_k127_2518841_8 chemotaxis protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003164 241.0
CMS2_k127_2518841_9 PFAM AhpC TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003488 246.0
CMS2_k127_253001_0 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 561.0
CMS2_k127_253001_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 513.0
CMS2_k127_253001_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 465.0
CMS2_k127_253001_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 378.0
CMS2_k127_253001_4 Receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000533 246.0
CMS2_k127_253001_6 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000006489 171.0
CMS2_k127_260397_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1260.0
CMS2_k127_260397_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 456.0
CMS2_k127_260397_10 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000001118 76.0
CMS2_k127_260397_2 COG1881 Phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001422 245.0
CMS2_k127_260397_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006287 243.0
CMS2_k127_260397_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002206 235.0
CMS2_k127_260397_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000007075 176.0
CMS2_k127_260397_6 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000001242 138.0
CMS2_k127_260397_7 - - - - 0.0000000000000000000000000000000001048 136.0
CMS2_k127_260397_8 Transcriptional regulator - - - 0.00000000000000000000000002561 114.0
CMS2_k127_260397_9 - - - - 0.000000000000000000008062 96.0
CMS2_k127_2628652_0 Peptidase s1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 452.0
CMS2_k127_2628652_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002989 281.0
CMS2_k127_2628652_2 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000005192 230.0
CMS2_k127_2628652_3 Protein of unknown function (DUF502) - - - 0.00000136 50.0
CMS2_k127_2651942_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 9.782e-290 914.0
CMS2_k127_2651942_1 Acts as a magnesium transporter K06213 - - 1.253e-233 729.0
CMS2_k127_2651942_10 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003009 267.0
CMS2_k127_2651942_11 - - - - 0.00000000000000000000000000000000000000000000000000006628 197.0
CMS2_k127_2651942_12 Putative ATP-dependant zinc protease - - - 0.0000000000000000000000000000000000000000000001337 171.0
CMS2_k127_2651942_13 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000000000002844 154.0
CMS2_k127_2651942_14 Small-conductance mechano-sensitive channel - - - 0.00000000000000000000000000000000000004718 149.0
CMS2_k127_2651942_15 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.000000000000000496 78.0
CMS2_k127_2651942_17 Phosphate-starvation-inducible E - - - 0.000002759 55.0
CMS2_k127_2651942_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 593.0
CMS2_k127_2651942_3 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 592.0
CMS2_k127_2651942_4 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 494.0
CMS2_k127_2651942_5 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 493.0
CMS2_k127_2651942_6 Belongs to the RimK family K05844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 490.0
CMS2_k127_2651942_7 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 378.0
CMS2_k127_2651942_8 CorA-like Mg2 transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 319.0
CMS2_k127_2651942_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 292.0
CMS2_k127_2661555_0 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 2.805e-206 650.0
CMS2_k127_2661555_1 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 511.0
CMS2_k127_2661555_2 HPP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003089 251.0
CMS2_k127_2661555_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000001338 233.0
CMS2_k127_2661555_4 Belongs to the globin family K05916 - 1.14.12.17 0.000000000000000000000000000000000000000000000000001037 186.0
CMS2_k127_2661555_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000001684 83.0
CMS2_k127_2663103_0 Diguanylate cyclase - - - 4.277e-230 727.0
CMS2_k127_2663103_1 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 349.0
CMS2_k127_2663103_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000005011 243.0
CMS2_k127_2663103_3 - - - - 0.0000000000000000000000000000000000000005986 148.0
CMS2_k127_280401_0 Two component regulator three Y domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 380.0
CMS2_k127_280401_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 321.0
CMS2_k127_280401_2 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 310.0
CMS2_k127_280401_3 PFAM PAS fold-3 domain protein K03776 - - 0.00000000000000000000000000000000000000000000000000000003057 198.0
CMS2_k127_280401_4 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000001426 124.0
CMS2_k127_2928501_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 7.855e-194 612.0
CMS2_k127_2928501_1 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.00000000000000000000000000000000000000000000002298 175.0
CMS2_k127_2928501_2 - - - - 0.000000000000000000000000000000000000000000001114 169.0
CMS2_k127_2928501_4 signal transduction histidine K07642,K18143 - 2.7.13.3 0.0001506 51.0
CMS2_k127_298615_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 7.019e-277 859.0
CMS2_k127_298615_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 385.0
CMS2_k127_298615_2 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 394.0
CMS2_k127_298615_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003059 268.0
CMS2_k127_298615_4 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000003058 266.0
CMS2_k127_298615_5 dna polymerase iii K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000001894 233.0
CMS2_k127_298615_6 Histidine kinase K13040 - 2.7.13.3 0.0000000000000000000000000000000000000000000001317 189.0
CMS2_k127_298615_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000001096 137.0
CMS2_k127_298615_8 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000001339 143.0
CMS2_k127_298615_9 Putative diguanylate phosphodiesterase - - - 0.000000000000001054 81.0
CMS2_k127_3058441_0 glutamine synthetase K01915 - 6.3.1.2 3.112e-301 925.0
CMS2_k127_3058441_1 peptidase U32 family K08303 - - 2.449e-223 698.0
CMS2_k127_3058441_10 that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001151 224.0
CMS2_k127_3058441_11 C-C_Bond_Lyase of the TIM-Barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000001656 216.0
CMS2_k127_3058441_12 Pfam Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000006313 195.0
CMS2_k127_3058441_13 Protein of unknown function (DUF3972) - - - 0.00000000000000000000000000000000000000000000000000001184 195.0
CMS2_k127_3058441_14 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000003952 166.0
CMS2_k127_3058441_2 histidinol phosphate phosphatase K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 389.0
CMS2_k127_3058441_3 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 377.0
CMS2_k127_3058441_4 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 362.0
CMS2_k127_3058441_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 281.0
CMS2_k127_3058441_6 GHKL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003377 287.0
CMS2_k127_3058441_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007883 281.0
CMS2_k127_3058441_8 that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007538 281.0
CMS2_k127_3058441_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004011 243.0
CMS2_k127_3067207_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 1.754e-194 609.0
CMS2_k127_3067207_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 427.0
CMS2_k127_3067207_2 membrane K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 389.0
CMS2_k127_3067207_3 Peptidase, M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002125 261.0
CMS2_k127_3067207_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000001093 254.0
CMS2_k127_3067207_5 DnaJ domain protein K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002738 258.0
CMS2_k127_3067207_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000000000000000000261 230.0
CMS2_k127_3081983_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 7.836e-279 863.0
CMS2_k127_3081983_1 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000001313 246.0
CMS2_k127_3098347_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1039.0
CMS2_k127_3098347_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295 534.0
CMS2_k127_3098347_10 Oxidoreductase K06151 - 1.1.99.3 0.00000000000000000000000000000001003 127.0
CMS2_k127_3098347_11 hmm pf01863 K07043 - - 0.0000000000000000000000002375 114.0
CMS2_k127_3098347_2 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 456.0
CMS2_k127_3098347_3 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 443.0
CMS2_k127_3098347_4 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 400.0
CMS2_k127_3098347_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 367.0
CMS2_k127_3098347_6 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 332.0
CMS2_k127_3098347_7 lytic murein transglycosylase K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 323.0
CMS2_k127_3098347_8 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001749 259.0
CMS2_k127_3098347_9 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001854 242.0
CMS2_k127_3100703_0 ATP-dependent CLP protease ATP-binding subunit K03694 - - 0.0 1028.0
CMS2_k127_3100703_1 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 604.0
CMS2_k127_3100703_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 291.0
CMS2_k127_3100703_3 Protein of unknown function (DUF3015) - - - 0.00000000000000000000000000000000000000000000000000000000000000001954 226.0
CMS2_k127_3100703_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000001699 146.0
CMS2_k127_3100703_5 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000495 126.0
CMS2_k127_3100703_6 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.0000000000000000000000463 100.0
CMS2_k127_3106391_0 DNA polymerase K02337 - 2.7.7.7 0.0 1970.0
CMS2_k127_3106391_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 1.609e-285 896.0
CMS2_k127_3106391_10 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 377.0
CMS2_k127_3106391_11 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 340.0
CMS2_k127_3106391_12 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000004203 252.0
CMS2_k127_3106391_13 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000009155 235.0
CMS2_k127_3106391_14 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.000000000000000000000000000000000000000000000003527 179.0
CMS2_k127_3106391_16 - - - - 0.000000000000000002269 89.0
CMS2_k127_3106391_17 Retinoic acid induced 14 - GO:0001650,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044452,GO:0044464,GO:0070013 - 0.000000000000000002933 93.0
CMS2_k127_3106391_18 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000001377 64.0
CMS2_k127_3106391_19 peptidyl-tyrosine sulfation - - - 0.0001088 53.0
CMS2_k127_3106391_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.174e-264 822.0
CMS2_k127_3106391_3 ribosomal protein S1 K02945 - - 6.032e-255 796.0
CMS2_k127_3106391_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 8.175e-203 638.0
CMS2_k127_3106391_5 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 535.0
CMS2_k127_3106391_6 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000921 516.0
CMS2_k127_3106391_7 Histidine kinase K02482,K07710 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 430.0
CMS2_k127_3106391_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 405.0
CMS2_k127_3106391_9 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 369.0
CMS2_k127_3170966_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 609.0
CMS2_k127_3170966_1 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 366.0
CMS2_k127_3170966_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 357.0
CMS2_k127_3170966_3 TIGRFAM cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 288.0
CMS2_k127_3170966_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000319 166.0
CMS2_k127_3170966_5 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.000000000000000000000000000000000000003983 150.0
CMS2_k127_3184414_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1053.0
CMS2_k127_3184414_1 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 7.675e-310 954.0
CMS2_k127_3184414_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001229 268.0
CMS2_k127_3184414_3 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000004511 235.0
CMS2_k127_3184414_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000001007 193.0
CMS2_k127_3184414_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000004648 108.0
CMS2_k127_3184414_6 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000000001964 89.0
CMS2_k127_3205988_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1152.0
CMS2_k127_3205988_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 6.35e-290 895.0
CMS2_k127_3205988_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000003921 229.0
CMS2_k127_3205988_11 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000002214 185.0
CMS2_k127_3205988_12 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000000000000000009157 167.0
CMS2_k127_3205988_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000127 148.0
CMS2_k127_3205988_14 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000552 104.0
CMS2_k127_3205988_2 3-deoxy-d-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 456.0
CMS2_k127_3205988_3 dinuclear metal center protein, YbgI K22391 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 364.0
CMS2_k127_3205988_4 Belongs to the pseudouridine synthase RluA family K06179,K06180 - 5.4.99.23,5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 334.0
CMS2_k127_3205988_5 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 325.0
CMS2_k127_3205988_6 COG1579 Zn-ribbon protein possibly nucleic acid-binding K07164,K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 289.0
CMS2_k127_3205988_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005843 280.0
CMS2_k127_3205988_8 membrane-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000757 246.0
CMS2_k127_3205988_9 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000133 231.0
CMS2_k127_3219351_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 396.0
CMS2_k127_3219351_1 RNase H K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 346.0
CMS2_k127_3219351_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002855 280.0
CMS2_k127_3219351_3 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000001389 79.0
CMS2_k127_3288825_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1355.0
CMS2_k127_3288825_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 553.0
CMS2_k127_3288825_10 - - - - 0.0000003835 57.0
CMS2_k127_3288825_2 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 549.0
CMS2_k127_3288825_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 528.0
CMS2_k127_3288825_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 515.0
CMS2_k127_3288825_5 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 426.0
CMS2_k127_3288825_6 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000000000000009918 219.0
CMS2_k127_3288825_7 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000003476 198.0
CMS2_k127_3288825_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000002832 143.0
CMS2_k127_3288825_9 (Lipo)protein K09860 - - 0.0000000000000000000000000000000001373 139.0
CMS2_k127_3306706_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 3e-306 948.0
CMS2_k127_3306706_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 4.986e-200 626.0
CMS2_k127_3306706_2 Belongs to the flagella basal body rod proteins family K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 421.0
CMS2_k127_3306706_3 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 420.0
CMS2_k127_3306706_4 flagellar basal body K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 329.0
CMS2_k127_3306706_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 287.0
CMS2_k127_3306706_6 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006038 268.0
CMS2_k127_3306706_7 phage repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000005784 227.0
CMS2_k127_3306706_8 - - - - 0.0000000000000000000001331 99.0
CMS2_k127_3306706_9 - - - - 0.000000000000000000002299 96.0
CMS2_k127_3310606_0 PFAM CheW domain protein - - - 1.862e-273 867.0
CMS2_k127_3310606_1 Acyltransferase K05939 - 2.3.1.40,6.2.1.20 1.266e-221 703.0
CMS2_k127_3310606_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 438.0
CMS2_k127_3310606_3 dehydrogenase K08325 - - 0.0000000000000000000000000000000000000000000000001876 178.0
CMS2_k127_3315432_0 COG0631 Serine threonine protein phosphatase K12132 - 2.7.11.1 1.326e-243 762.0
CMS2_k127_3315432_1 COG2223 Nitrate nitrite transporter K02575 - - 3.348e-228 714.0
CMS2_k127_3315432_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007216 265.0
CMS2_k127_3317329_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 534.0
CMS2_k127_3317329_1 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 414.0
CMS2_k127_3317329_2 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000002054 224.0
CMS2_k127_3317329_3 Hit family K02503 - - 0.00000000000000000000000000000000000000000000000000001244 191.0
CMS2_k127_3340223_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 505.0
CMS2_k127_3340223_1 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 432.0
CMS2_k127_3340223_2 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 391.0
CMS2_k127_3340223_3 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 352.0
CMS2_k127_3340223_4 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 322.0
CMS2_k127_3340223_5 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 306.0
CMS2_k127_3340223_6 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000008095 183.0
CMS2_k127_3340223_7 Protein of unknown function (DUF4238) - - - 0.0000000000000000000002973 97.0
CMS2_k127_3340223_8 - - - - 0.000000000000000001788 89.0
CMS2_k127_3438524_0 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 327.0
CMS2_k127_3438524_1 PFAM EAL domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 304.0
CMS2_k127_3438524_2 PFAM dUTPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005016 267.0
CMS2_k127_3438524_3 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000001372 226.0
CMS2_k127_3438524_4 cofactor binding K09979 - - 0.0000000000000000000000000000000103 131.0
CMS2_k127_3438524_5 - - - - 0.00000000000000001918 85.0
CMS2_k127_3438524_7 Cytochrome c - - - 0.000000007456 57.0
CMS2_k127_3452325_0 COG0642 Signal transduction histidine kinase - - - 1.143e-232 737.0
CMS2_k127_3452325_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 2.558e-223 697.0
CMS2_k127_3452325_2 fructose-bisphosphate aldolase K01624 - 4.1.2.13 2.3e-198 621.0
CMS2_k127_3452325_3 Histidine kinase K20972 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 503.0
CMS2_k127_3452325_4 PFAM 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 411.0
CMS2_k127_3452325_5 peptidylprolyl isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 310.0
CMS2_k127_3452325_6 1-aminocyclopropane-1-carboxylate deaminase K01505 - 3.5.99.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 289.0
CMS2_k127_3452325_7 Membrane - - - 0.000000000000000000000004235 108.0
CMS2_k127_3452325_8 PFAM Cupin domain K11312 - - 0.000000000000000001321 89.0
CMS2_k127_3452325_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000005694 61.0
CMS2_k127_3456892_0 Arginosuccinate synthase K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 510.0
CMS2_k127_3456892_1 - - - - 0.0000000000000000000000000000000000003434 145.0
CMS2_k127_3456892_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000002665 68.0
CMS2_k127_3456892_3 CheR methyltransferase, SAM binding domain K13924 - 2.1.1.80,3.1.1.61 0.00000000002812 64.0
CMS2_k127_3461906_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1043.0
CMS2_k127_3461906_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 1.761e-265 830.0
CMS2_k127_3461906_10 PFAM response regulator receiver K03407,K03413 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000007542 192.0
CMS2_k127_3461906_11 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000002798 185.0
CMS2_k127_3461906_12 GGDEF domain K03413 - - 0.000000000000000000000000000000000000000000000583 168.0
CMS2_k127_3461906_13 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000001428 138.0
CMS2_k127_3461906_14 Nitroreductase family - - - 0.000000000000000000000000001573 114.0
CMS2_k127_3461906_16 COG0835 Chemotaxis signal transduction protein - - - 0.00000000000000000001979 101.0
CMS2_k127_3461906_2 phosphohydrolase (DHH superfamily) K07097 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 480.0
CMS2_k127_3461906_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 421.0
CMS2_k127_3461906_4 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 379.0
CMS2_k127_3461906_5 Signal transducing histidine kinase, homodimeric domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 390.0
CMS2_k127_3461906_6 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 334.0
CMS2_k127_3461906_7 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000131 256.0
CMS2_k127_3461906_8 PAS fold K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002161 248.0
CMS2_k127_3461906_9 NUBPL iron-transfer P-loop NTPase K03496 - - 0.00000000000000000000000000000000000000000000000000000001348 199.0
CMS2_k127_3505545_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1082.0
CMS2_k127_3505545_1 ABC transporter, ATP-binding protein K15738 - - 4.603e-291 906.0
CMS2_k127_3505545_10 Protein of unknown function (DUF2459) - - - 0.0000000000000000000000000000000000000000000000000000000003374 208.0
CMS2_k127_3505545_11 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000005476 180.0
CMS2_k127_3505545_12 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000001958 131.0
CMS2_k127_3505545_13 membrane - - - 0.00000000000000000000000000000002948 131.0
CMS2_k127_3505545_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 9.292e-222 695.0
CMS2_k127_3505545_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 6.402e-220 687.0
CMS2_k127_3505545_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 537.0
CMS2_k127_3505545_5 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 534.0
CMS2_k127_3505545_6 Mate efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 446.0
CMS2_k127_3505545_7 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 419.0
CMS2_k127_3505545_8 abc transporter atp-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 354.0
CMS2_k127_3505545_9 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 296.0
CMS2_k127_3522006_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.292e-261 831.0
CMS2_k127_3522006_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 2.287e-198 621.0
CMS2_k127_3522006_2 Anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000002939 237.0
CMS2_k127_3522006_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000005366 116.0
CMS2_k127_3522006_4 Glycosyltransferase like family 2 K20444 - - 0.00000000005195 67.0
CMS2_k127_3522006_5 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0002458 47.0
CMS2_k127_3694879_0 Pfam Transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 384.0
CMS2_k127_3694879_1 HAD-superfamily hydrolase, subfamily IIB K07026,K15918 - 2.7.1.31,3.1.3.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001762 282.0
CMS2_k127_3694879_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000001922 274.0
CMS2_k127_3694879_3 FMN binding - - - 0.000000000000000000000000000000000000000000002007 169.0
CMS2_k127_3694879_4 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000006679 141.0
CMS2_k127_3694879_5 Family of unknown function (DUF695) - - - 0.000000000000000000000000000002634 129.0
CMS2_k127_3694879_6 - - - - 0.00000000000001166 78.0
CMS2_k127_3694879_7 - - - - 0.00002424 55.0
CMS2_k127_3748183_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1037.0
CMS2_k127_3748183_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.199e-230 715.0
CMS2_k127_3748183_2 Aminotransferase K14261 - - 4.145e-228 710.0
CMS2_k127_3748183_3 homoserine dehydrogenase K00003 - 1.1.1.3 2.633e-197 621.0
CMS2_k127_3748183_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 503.0
CMS2_k127_3748183_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 411.0
CMS2_k127_3748183_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001584 277.0
CMS2_k127_3748183_7 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000002014 200.0
CMS2_k127_3748183_8 - - - - 0.000000000000000000000000000000000000000000000000003057 185.0
CMS2_k127_3748183_9 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000001794 118.0
CMS2_k127_3751159_0 - - - - 1.621e-209 659.0
CMS2_k127_3751159_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 551.0
CMS2_k127_3751159_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000004368 211.0
CMS2_k127_3751159_3 Thioredoxin K07396 - - 0.000000000000000000000000000000000000000000000000000008293 196.0
CMS2_k127_3751159_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000001733 187.0
CMS2_k127_3751159_5 PFAM DsrE DsrF-like family - - - 0.00000000000000000000000000000000000000000002943 163.0
CMS2_k127_3751159_6 - - - - 0.000000000000000000000000000000000000003965 158.0
CMS2_k127_3751159_7 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000008727 136.0
CMS2_k127_3751159_8 DnaK suppressor protein K06204 - - 0.000000000000000000000001886 106.0
CMS2_k127_3751159_9 Protein of unknown function (DUF1295) - - - 0.000000000000000000003545 98.0
CMS2_k127_3807373_0 flagellar hook-associated protein K02396 - - 2.219e-207 662.0
CMS2_k127_3807373_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 477.0
CMS2_k127_3807373_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 432.0
CMS2_k127_3807373_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034,K12370 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 361.0
CMS2_k127_3807373_4 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000003673 228.0
CMS2_k127_3807373_5 - - - - 0.00000000000000000000000000000000000000000000007453 172.0
CMS2_k127_3807373_6 - - - - 0.00000000000000000000000000002746 121.0
CMS2_k127_3807373_7 Rod binding protein - - - 0.00000000000000000000003776 103.0
CMS2_k127_3807373_8 Anti-sigma-28 factor, FlgM - - - 0.0000000001164 64.0
CMS2_k127_3875930_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 548.0
CMS2_k127_3875930_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 341.0
CMS2_k127_3892663_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 564.0
CMS2_k127_3892663_1 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 514.0
CMS2_k127_3892663_2 pyridine nucleotide-disulfide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 494.0
CMS2_k127_3892663_3 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 293.0
CMS2_k127_3892663_4 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001843 279.0
CMS2_k127_3892663_5 COGs COG4087 Soluble P-type ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000004178 221.0
CMS2_k127_3892663_6 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000001088 138.0
CMS2_k127_4096107_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1450.0
CMS2_k127_4096107_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.446e-206 650.0
CMS2_k127_4096107_2 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 410.0
CMS2_k127_4096107_3 - - - - 0.0000000000001918 73.0
CMS2_k127_4096107_4 - - - - 0.0000003439 52.0
CMS2_k127_4096107_5 - - - - 0.00000987 48.0
CMS2_k127_4111864_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.055e-224 700.0
CMS2_k127_4111864_1 Cytochrome c oxidase accessory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 580.0
CMS2_k127_4111864_10 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000006289 222.0
CMS2_k127_4111864_11 - - - - 0.000000000000000000000000000000000000000000000000000000000003773 211.0
CMS2_k127_4111864_12 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000000002986 202.0
CMS2_k127_4111864_13 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000006851 158.0
CMS2_k127_4111864_14 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000000004052 144.0
CMS2_k127_4111864_15 Signal transduction protein - - - 0.000000000000000000000000000000008678 145.0
CMS2_k127_4111864_16 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000006076 127.0
CMS2_k127_4111864_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 548.0
CMS2_k127_4111864_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 547.0
CMS2_k127_4111864_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 543.0
CMS2_k127_4111864_5 Receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 540.0
CMS2_k127_4111864_6 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 361.0
CMS2_k127_4111864_7 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 332.0
CMS2_k127_4111864_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 329.0
CMS2_k127_4111864_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 313.0
CMS2_k127_4144053_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 342.0
CMS2_k127_4144053_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000001625 249.0
CMS2_k127_4144053_2 Mannosyl-glycoprotein K03796 - - 0.00000000000000000000000000000000000000000000000000000000000000007831 229.0
CMS2_k127_4144053_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003432 226.0
CMS2_k127_4144053_4 chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000004147 201.0
CMS2_k127_4144053_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000001692 182.0
CMS2_k127_4152182_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1283.0
CMS2_k127_4152182_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 555.0
CMS2_k127_4152182_2 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000008894 214.0
CMS2_k127_4152182_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000003738 167.0
CMS2_k127_4152182_4 peptidyl-tyrosine sulfation - - - 0.00000000004565 68.0
CMS2_k127_4157396_0 PFAM biotin lipoyl attachment domain-containing protein K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 582.0
CMS2_k127_4157396_1 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 516.0
CMS2_k127_4157396_10 Amino Acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 305.0
CMS2_k127_4157396_11 peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006451 250.0
CMS2_k127_4157396_12 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000001526 223.0
CMS2_k127_4157396_13 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000000000000000007366 209.0
CMS2_k127_4157396_14 Cell division protein FtsX K09811 - - 0.000000000000000000000000000000000000006599 156.0
CMS2_k127_4157396_15 - - - - 0.000000000000000000000000000000000000008092 146.0
CMS2_k127_4157396_17 - - - - 0.0000000000000000000000001448 109.0
CMS2_k127_4157396_18 - - - - 0.00000000000000002689 87.0
CMS2_k127_4157396_19 Oxaloacetate decarboxylase, gamma chain K01573 - 4.1.1.3 0.000000000000004601 78.0
CMS2_k127_4157396_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 435.0
CMS2_k127_4157396_20 - - - - 0.00000000001387 72.0
CMS2_k127_4157396_21 FlaG protein K06603 - - 0.0000000001102 65.0
CMS2_k127_4157396_3 na -driven multidrug efflux - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 429.0
CMS2_k127_4157396_4 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 422.0
CMS2_k127_4157396_5 Fibronectin type 3 domain-containing protein K06882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 409.0
CMS2_k127_4157396_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 404.0
CMS2_k127_4157396_7 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 347.0
CMS2_k127_4157396_8 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 332.0
CMS2_k127_4157396_9 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 314.0
CMS2_k127_4161038_0 chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 434.0
CMS2_k127_4161038_1 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 337.0
CMS2_k127_4161038_2 PAS domain K03776 - - 0.0000000000000000000000000000000000000001719 155.0
CMS2_k127_4161038_3 PFAM response regulator receiver - - - 0.0000000000000000000000000000000004826 140.0
CMS2_k127_4161038_5 - - - - 0.0000002753 52.0
CMS2_k127_4161038_6 - - - - 0.0000003026 51.0
CMS2_k127_4161038_7 - - - - 0.00003433 48.0
CMS2_k127_4184410_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1324.0
CMS2_k127_4184410_1 DNA helicase K03657 - 3.6.4.12 0.0 1022.0
CMS2_k127_4184410_10 apolipoprotein N-acyltransferase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 408.0
CMS2_k127_4184410_11 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 385.0
CMS2_k127_4184410_12 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 365.0
CMS2_k127_4184410_13 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 340.0
CMS2_k127_4184410_14 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 337.0
CMS2_k127_4184410_15 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 320.0
CMS2_k127_4184410_16 ubiquinol cytochrome c oxidoreductase, cytochrome c1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 310.0
CMS2_k127_4184410_17 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin K00477 - 1.14.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 299.0
CMS2_k127_4184410_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 299.0
CMS2_k127_4184410_19 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 293.0
CMS2_k127_4184410_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 9.228e-319 985.0
CMS2_k127_4184410_20 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000006142 258.0
CMS2_k127_4184410_21 Glycosyl transferase family, helical bundle domain - - - 0.0000000000000000000000000000000000000000000000000000000000003246 222.0
CMS2_k127_4184410_22 - - - - 0.0000000000000000000000000000000000000000000000000007236 187.0
CMS2_k127_4184410_23 - - - - 0.000000000000000000000000000000000000000000000000001377 184.0
CMS2_k127_4184410_24 Lipopolysaccharide-assembly - - - 0.00000000000000000000000000000000000000000000001305 177.0
CMS2_k127_4184410_25 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000005147 177.0
CMS2_k127_4184410_26 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000002485 165.0
CMS2_k127_4184410_27 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000007615 117.0
CMS2_k127_4184410_28 Preprotein translocase K03210 - - 0.00000000000000000000005643 100.0
CMS2_k127_4184410_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 3.087e-230 723.0
CMS2_k127_4184410_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 4.642e-226 704.0
CMS2_k127_4184410_5 ADP-ribosylglycohydrolase - - - 7.505e-194 608.0
CMS2_k127_4184410_6 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 497.0
CMS2_k127_4184410_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008436 478.0
CMS2_k127_4184410_8 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 463.0
CMS2_k127_4184410_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 461.0
CMS2_k127_4242912_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 8.4e-244 755.0
CMS2_k127_4242912_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.574e-202 638.0
CMS2_k127_4242912_10 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000002789 182.0
CMS2_k127_4242912_11 FlaG protein K06603 - - 0.000000000000000001469 85.0
CMS2_k127_4242912_2 Pilus assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 523.0
CMS2_k127_4242912_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 412.0
CMS2_k127_4242912_4 C-terminal domain of metallo-carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 407.0
CMS2_k127_4242912_5 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 371.0
CMS2_k127_4242912_6 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 332.0
CMS2_k127_4242912_7 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 305.0
CMS2_k127_4242912_8 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007515 300.0
CMS2_k127_4242912_9 - - - - 0.000000000000000000000000000000000000000000000000000000000001819 215.0
CMS2_k127_4318148_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 3.652e-233 729.0
CMS2_k127_4318148_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 490.0
CMS2_k127_4318148_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 490.0
CMS2_k127_4318148_3 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 419.0
CMS2_k127_4318148_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000008278 150.0
CMS2_k127_4318148_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000037 134.0
CMS2_k127_4375170_0 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 521.0
CMS2_k127_4375170_1 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001136 253.0
CMS2_k127_4375170_2 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000000000000000000002899 176.0
CMS2_k127_4375170_3 GGDEF EAL family protein - - - 0.0000000000000000000000000000000000000000001199 161.0
CMS2_k127_4375170_4 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000000000000001131 126.0
CMS2_k127_4379528_0 monooxygenase activity - - - 0.0000000000000000000000002337 111.0
CMS2_k127_4379528_2 PFAM Alpha Beta hydrolase K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 - 0.00000000009253 65.0
CMS2_k127_4379528_3 COG0553 Superfamily II DNA RNA helicases, SNF2 family K08282 - 2.7.11.1 0.0003573 48.0
CMS2_k127_4444503_0 COG4886 Leucine-rich repeat (LRR) protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 606.0
CMS2_k127_4444503_1 flagellar biosynthesis K02404 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 588.0
CMS2_k127_4444503_10 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002861 278.0
CMS2_k127_4444503_11 chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001038 289.0
CMS2_k127_4444503_12 flagellar motor switch protein K02417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000132 269.0
CMS2_k127_4444503_13 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000001828 190.0
CMS2_k127_4444503_14 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000382 163.0
CMS2_k127_4444503_15 dehydrogenase reductase - - - 0.00000000000000000000000000000000000000005795 155.0
CMS2_k127_4444503_17 - - - - 0.00000000000000000000003422 102.0
CMS2_k127_4444503_19 - - - - 0.000000000002762 72.0
CMS2_k127_4444503_2 flagellar motor switch protein K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 583.0
CMS2_k127_4444503_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 564.0
CMS2_k127_4444503_4 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 542.0
CMS2_k127_4444503_5 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 492.0
CMS2_k127_4444503_6 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 408.0
CMS2_k127_4444503_7 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 351.0
CMS2_k127_4444503_8 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 335.0
CMS2_k127_4444503_9 Belongs to the sigma-70 factor family K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 314.0
CMS2_k127_4454077_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.196e-252 786.0
CMS2_k127_4454077_1 Belongs to the GARS family K01945 - 6.3.4.13 9.87e-228 710.0
CMS2_k127_4454077_2 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 4.986e-218 684.0
CMS2_k127_4454077_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 403.0
CMS2_k127_4454077_4 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000001667 158.0
CMS2_k127_4477239_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 540.0
CMS2_k127_4477239_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 518.0
CMS2_k127_4477239_2 ABC transporter permease K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 461.0
CMS2_k127_4477239_3 - - - - 0.0000000000000000000000000004604 115.0
CMS2_k127_4477239_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000288 49.0
CMS2_k127_453101_0 Glycerol-3-phosphate dehydrogenase K11473 - - 1.548e-222 696.0
CMS2_k127_453101_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 537.0
CMS2_k127_453101_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 391.0
CMS2_k127_453101_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 369.0
CMS2_k127_453101_4 acid membrane antigen A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 355.0
CMS2_k127_453101_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000001988 256.0
CMS2_k127_453101_6 Histidine kinase K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000004895 199.0
CMS2_k127_453101_7 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000001811 145.0
CMS2_k127_4539565_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1482.0
CMS2_k127_4539565_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1152.0
CMS2_k127_4539565_2 Cytochrome c biogenesis protein - - - 4.314e-195 629.0
CMS2_k127_4539565_3 Signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 383.0
CMS2_k127_4539565_4 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006755 258.0
CMS2_k127_4565407_0 Belongs to the ClpA ClpB family K03694,K03695 - - 0.0 1302.0
CMS2_k127_4565407_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 8.607e-215 670.0
CMS2_k127_4565407_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000001074 117.0
CMS2_k127_4565407_11 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000007388 100.0
CMS2_k127_4565407_12 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.0000000000000145 75.0
CMS2_k127_4565407_13 PFAM Prenyltransferase squalene oxidase - - - 0.000001378 59.0
CMS2_k127_4565407_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 587.0
CMS2_k127_4565407_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 419.0
CMS2_k127_4565407_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 371.0
CMS2_k127_4565407_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003523 259.0
CMS2_k127_4565407_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000002691 218.0
CMS2_k127_4565407_7 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000001087 164.0
CMS2_k127_4565407_8 - - - - 0.000000000000000000000000000000000009123 138.0
CMS2_k127_4595305_0 Belongs to the aldehyde dehydrogenase family - - - 2.652e-241 752.0
CMS2_k127_4595305_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 533.0
CMS2_k127_4595305_2 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 374.0
CMS2_k127_4595305_3 COG2346 Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000000000005567 206.0
CMS2_k127_4595305_4 Protein of unknown function (DUF523) - - - 0.0000000000000000000000006147 106.0
CMS2_k127_4661371_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 567.0
CMS2_k127_4661371_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 349.0
CMS2_k127_4719091_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 557.0
CMS2_k127_4719091_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 364.0
CMS2_k127_4719091_10 RNA-binding protein K06960 - - 0.00000000000000000000000000000009006 125.0
CMS2_k127_4719091_2 molybdopterin biosynthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 366.0
CMS2_k127_4719091_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 353.0
CMS2_k127_4719091_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 331.0
CMS2_k127_4719091_5 General glycosylation pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 311.0
CMS2_k127_4719091_6 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 297.0
CMS2_k127_4719091_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000002202 188.0
CMS2_k127_4719091_8 Ribosomal protein L19 K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000006372 134.0
CMS2_k127_4719091_9 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000008587 131.0
CMS2_k127_4753540_0 acetolactate synthase K01652 - 2.2.1.6 6.24e-311 958.0
CMS2_k127_4753540_1 arginine decarboxylase K01585 - 4.1.1.19 5.819e-293 910.0
CMS2_k127_4753540_10 forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 385.0
CMS2_k127_4753540_11 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 381.0
CMS2_k127_4753540_12 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 361.0
CMS2_k127_4753540_13 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 359.0
CMS2_k127_4753540_14 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001662 280.0
CMS2_k127_4753540_15 acetolactate synthase K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000007052 242.0
CMS2_k127_4753540_16 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000001069 218.0
CMS2_k127_4753540_17 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000008842 171.0
CMS2_k127_4753540_19 - - - - 0.0000000000000000000000000009203 113.0
CMS2_k127_4753540_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 4.965e-201 635.0
CMS2_k127_4753540_20 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000001481 90.0
CMS2_k127_4753540_3 HI0933-like protein K07007 - - 1.153e-195 616.0
CMS2_k127_4753540_4 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 603.0
CMS2_k127_4753540_5 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 571.0
CMS2_k127_4753540_6 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 570.0
CMS2_k127_4753540_7 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 522.0
CMS2_k127_4753540_8 Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) K00557 - 2.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 497.0
CMS2_k127_4753540_9 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 392.0
CMS2_k127_4855502_0 penicillin-binding protein K05515 - 3.4.16.4 3.473e-245 770.0
CMS2_k127_4855502_1 K -dependent Na Ca exchanger K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 336.0
CMS2_k127_4855502_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008647 271.0
CMS2_k127_4855502_3 acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000002303 211.0
CMS2_k127_4855502_4 Lipopolysaccharide transport periplasmic protein lpta K09774 - - 0.0000000000000000000000000000000000000003289 154.0
CMS2_k127_4855502_5 - - - - 0.00000000000000000000003584 104.0
CMS2_k127_4855502_6 - - - - 0.00000000000000000002238 97.0
CMS2_k127_4885375_0 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 462.0
CMS2_k127_4885375_1 Protein of unknown function (DUF3137) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 353.0
CMS2_k127_4885375_10 Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000001754 111.0
CMS2_k127_4885375_12 Belongs to the UPF0312 family - - - 0.000000000008741 69.0
CMS2_k127_4885375_13 - - - - 0.000003359 57.0
CMS2_k127_4885375_2 ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 346.0
CMS2_k127_4885375_3 SMART GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005658 279.0
CMS2_k127_4885375_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008808 255.0
CMS2_k127_4885375_5 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000001131 233.0
CMS2_k127_4885375_6 - K21817 - 1.13.11.63 0.00000000000000000000000000000000000000000000000000000002668 208.0
CMS2_k127_4885375_7 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000003055 203.0
CMS2_k127_4885375_9 bacteriocin export ABC transporter, lactococcin 972 group K02003 - - 0.00000000000000000000000000000009679 133.0
CMS2_k127_49341_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 3.134e-307 956.0
CMS2_k127_49341_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 578.0
CMS2_k127_49341_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 536.0
CMS2_k127_49341_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 348.0
CMS2_k127_49341_4 - - - - 0.00000000000000000000000769 104.0
CMS2_k127_49341_5 HD domain - - - 0.000000000003464 70.0
CMS2_k127_5093342_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 1.983e-201 637.0
CMS2_k127_5093342_1 ADP-L-glycero-D-manno-heptose-6-epimerase K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 571.0
CMS2_k127_5093342_2 heptosyltransferase ii K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 426.0
CMS2_k127_5093342_3 lipopolysaccharide core region biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 395.0
CMS2_k127_5093342_4 - - - - 0.00000000000000000000000000000000000001068 152.0
CMS2_k127_5093342_5 Cytochrome c553 K08738 - - 0.0000000000000000000000000000000002903 133.0
CMS2_k127_5093342_6 VanZ like family - - - 0.00000000238 63.0
CMS2_k127_5104567_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 1.818e-290 917.0
CMS2_k127_5104567_1 Fatty acid cis/trans isomerase (CTI) - - - 1.327e-265 840.0
CMS2_k127_5104567_2 COG3893 inactivated superfamily I helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 536.0
CMS2_k127_5104567_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000009625 64.0
CMS2_k127_5153480_0 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 5.992e-203 637.0
CMS2_k127_5153480_1 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 558.0
CMS2_k127_5153480_2 TIGRFAM SagB-type dehydrogenase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005008 284.0
CMS2_k127_5153480_3 AhpC/TSA family K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001619 268.0
CMS2_k127_5153480_4 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000009211 203.0
CMS2_k127_5153480_5 Ferredoxin - - - 0.000000000000000000000000000002244 122.0
CMS2_k127_5153480_6 - - - - 0.0000000000000000000000174 103.0
CMS2_k127_5154307_0 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 575.0
CMS2_k127_5154307_1 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 531.0
CMS2_k127_5154307_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 522.0
CMS2_k127_5154307_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 517.0
CMS2_k127_5167562_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 2.319e-218 693.0
CMS2_k127_5167562_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K03776 - - 0.00000000000000000000000000000000000000000000000000000000002011 209.0
CMS2_k127_5167562_2 - - - - 0.00000000000000000000000000008526 120.0
CMS2_k127_5167562_3 Histidine kinase - - - 0.0000000000000000000000000009976 114.0
CMS2_k127_5169477_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 6.407e-274 857.0
CMS2_k127_5169477_1 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 370.0
CMS2_k127_5169477_2 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.00000000000000000000000000000000000000000000000000000001641 199.0
CMS2_k127_5170253_0 threonine synthase K01733 - 4.2.3.1 2.291e-240 750.0
CMS2_k127_5170253_1 Highly conserved protein containing a thioredoxin domain K06888 - - 1.643e-222 707.0
CMS2_k127_5170253_2 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 531.0
CMS2_k127_5170253_3 polyphosphate kinase K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 462.0
CMS2_k127_5170253_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 410.0
CMS2_k127_5170253_5 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 348.0
CMS2_k127_5170253_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006705 296.0
CMS2_k127_5170253_7 HAMP domain - - - 0.000000000000000000000000000000000000000000000000000000000000003716 243.0
CMS2_k127_5170253_8 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000000000008667 137.0
CMS2_k127_5170253_9 cytochrome c class I - - - 0.000000000000000000001718 101.0
CMS2_k127_5182044_0 Belongs to the GARS family K01945 - 6.3.4.13 2.572e-229 714.0
CMS2_k127_5182044_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 372.0
CMS2_k127_5182044_2 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000002201 161.0
CMS2_k127_5182044_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000001109 132.0
CMS2_k127_5182044_4 RDD family - - - 0.000000000000000000000000000202 119.0
CMS2_k127_5184344_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 8.816e-243 752.0
CMS2_k127_5184344_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 3.618e-236 736.0
CMS2_k127_5184344_10 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 349.0
CMS2_k127_5184344_11 Domain of unknown function (DUF1882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 331.0
CMS2_k127_5184344_12 Tetratricopeptide repeat K21007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000161 314.0
CMS2_k127_5184344_13 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003565 277.0
CMS2_k127_5184344_14 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004826 275.0
CMS2_k127_5184344_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004341 280.0
CMS2_k127_5184344_16 Belongs to the Fur family K03711 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 250.0
CMS2_k127_5184344_17 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000001992 239.0
CMS2_k127_5184344_18 COG2199 FOG GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000001482 226.0
CMS2_k127_5184344_19 Colicin V production protein K03558 - - 0.0000000000000000000000000000000000000000000000000000000000009118 216.0
CMS2_k127_5184344_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 4.889e-228 715.0
CMS2_k127_5184344_20 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000002089 204.0
CMS2_k127_5184344_21 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000001515 194.0
CMS2_k127_5184344_22 PelD GGDEF domain K21009 - - 0.0000000000000000000000000000000000000000000000000001042 201.0
CMS2_k127_5184344_23 Cell division protein K03591,K03749 - - 0.000000000000000000000000000000000000000000000005112 180.0
CMS2_k127_5184344_24 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000003442 167.0
CMS2_k127_5184344_25 ArsC family - - - 0.0000000000000000000000000000000000000005858 151.0
CMS2_k127_5184344_26 - - - - 0.0000000000000000000000000000000000000008546 156.0
CMS2_k127_5184344_27 - - - - 0.00000000000000000000000000000006671 127.0
CMS2_k127_5184344_28 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000533 119.0
CMS2_k127_5184344_29 cAMP biosynthetic process K21008 - - 0.000000000000000000000000001303 118.0
CMS2_k127_5184344_3 Glycoside-hydrolase family GH114 K21006 - - 1.288e-221 717.0
CMS2_k127_5184344_30 membrane K21012 - - 0.000000000000000000000000001813 127.0
CMS2_k127_5184344_31 chaperone-mediated protein folding K21010 - - 0.0000000000000000000634 101.0
CMS2_k127_5184344_32 - - - - 0.00000000000000000035 90.0
CMS2_k127_5184344_33 - - - - 0.0000000000000579 83.0
CMS2_k127_5184344_4 anthranilate synthase component K01657 - 4.1.3.27 1.955e-219 688.0
CMS2_k127_5184344_5 glycosyl transferase group 1 K21011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 596.0
CMS2_k127_5184344_6 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 583.0
CMS2_k127_5184344_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 375.0
CMS2_k127_5184344_8 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 364.0
CMS2_k127_5184344_9 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 376.0
CMS2_k127_5188841_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.904e-305 958.0
CMS2_k127_5188841_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 464.0
CMS2_k127_5188841_2 riboflavin biosynthesis protein K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 381.0
CMS2_k127_5188841_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 351.0
CMS2_k127_5188841_4 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 291.0
CMS2_k127_5188841_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000001345 178.0
CMS2_k127_5188841_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000006195 169.0
CMS2_k127_5188841_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000001458 168.0
CMS2_k127_5188841_8 nucleic-acid-binding protein implicated in transcription termination - - - 0.000000000000009754 76.0
CMS2_k127_5190021_0 Protein of unknown function (DUF1538) - - - 4.296e-208 659.0
CMS2_k127_5190021_1 GAF domain - - - 0.0000000000000000000000000000000000000000000000004288 180.0
CMS2_k127_5190021_2 COG1393 Arsenate reductase and related K00537 - 1.20.4.1 0.0000000000000000000000000000000000000004272 152.0
CMS2_k127_5190021_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000002039 139.0
CMS2_k127_5190021_4 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000002257 132.0
CMS2_k127_5190021_5 GAF domain - - - 0.000000000001163 69.0
CMS2_k127_5190332_0 nuclear chromosome segregation - - - 8.891e-285 892.0
CMS2_k127_5190332_1 abc transporter atp-binding protein - - - 1.324e-281 872.0
CMS2_k127_5190332_10 diguanylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003551 288.0
CMS2_k127_5190332_11 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001224 263.0
CMS2_k127_5190332_12 Esterase-like activity of phytase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001583 252.0
CMS2_k127_5190332_13 methyltransferase activity - - - 0.000000000000000000000000000000000000004873 146.0
CMS2_k127_5190332_14 Rhodanese-like domain - - - 0.0000000000000000000000000000000000002251 144.0
CMS2_k127_5190332_15 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000271 130.0
CMS2_k127_5190332_16 Protein of unknown function (DUF3185) - - - 0.000000000000000000000000000001751 122.0
CMS2_k127_5190332_18 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000001801 120.0
CMS2_k127_5190332_19 Translation initiation factor SUI1 K03113 - - 0.000000000000000000000000002596 114.0
CMS2_k127_5190332_2 Histidine kinase K03407 - 2.7.13.3 9.063e-212 677.0
CMS2_k127_5190332_20 SCO1/SenC K07152 - - 0.00000000000000000000000002869 115.0
CMS2_k127_5190332_21 Protein of unknown function (DUF1653) - - - 0.00000000000000000000001001 101.0
CMS2_k127_5190332_22 - - - - 0.00000000000000000005836 94.0
CMS2_k127_5190332_23 META domain - - - 0.0000000000001424 76.0
CMS2_k127_5190332_3 HD domain - - - 7.765e-201 636.0
CMS2_k127_5190332_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 607.0
CMS2_k127_5190332_5 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 387.0
CMS2_k127_5190332_6 protein hemolysin III K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 356.0
CMS2_k127_5190332_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 341.0
CMS2_k127_5190332_8 COG2199 FOG GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 345.0
CMS2_k127_5190332_9 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 316.0
CMS2_k127_5196801_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1233.0
CMS2_k127_5196801_1 PFAM Helicase conserved C-terminal domain K03579 - 3.6.4.13 0.0 1137.0
CMS2_k127_5196801_10 Amidase K01457 - 3.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 476.0
CMS2_k127_5196801_11 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 457.0
CMS2_k127_5196801_12 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 464.0
CMS2_k127_5196801_13 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 402.0
CMS2_k127_5196801_14 Flagellar basal body protein K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 377.0
CMS2_k127_5196801_15 phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 366.0
CMS2_k127_5196801_16 (EAL) domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 342.0
CMS2_k127_5196801_17 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 324.0
CMS2_k127_5196801_18 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 284.0
CMS2_k127_5196801_19 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001307 272.0
CMS2_k127_5196801_2 Flagellar basal body protein K02390 - - 2.868e-226 716.0
CMS2_k127_5196801_20 PhoU family K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
CMS2_k127_5196801_21 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000000004893 255.0
CMS2_k127_5196801_22 Signal transduction protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000258 253.0
CMS2_k127_5196801_23 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003067 251.0
CMS2_k127_5196801_24 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000002272 242.0
CMS2_k127_5196801_25 - K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000001835 220.0
CMS2_k127_5196801_26 amidase activity K01457 - 3.5.1.54 0.000000000000000000000000000000000000000000000000000000000001308 211.0
CMS2_k127_5196801_27 Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000001825 206.0
CMS2_k127_5196801_28 mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000004387 224.0
CMS2_k127_5196801_29 - K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000002623 205.0
CMS2_k127_5196801_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.917e-198 625.0
CMS2_k127_5196801_30 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000000000002063 198.0
CMS2_k127_5196801_31 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000003019 199.0
CMS2_k127_5196801_32 Belongs to the UPF0061 (SELO) family - - - 0.0000000000000000000000000000000000000000000000005325 180.0
CMS2_k127_5196801_33 TraB family K09973 - - 0.000000000000000000000000000000000000000000006435 175.0
CMS2_k127_5196801_34 Flagellar hook-length control protein FliK - - - 0.00000000000000000000000000000000000000003136 168.0
CMS2_k127_5196801_35 superoxide reductase activity K05919 - 1.15.1.2 0.00000000000000000000000000000000002956 139.0
CMS2_k127_5196801_36 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000007828 135.0
CMS2_k127_5196801_37 membrane - - - 0.00000000000000000000000000005805 121.0
CMS2_k127_5196801_38 MOSC domain - - - 0.0000000000000000000000000004615 121.0
CMS2_k127_5196801_39 - - - - 0.000000000000000000000000008162 114.0
CMS2_k127_5196801_4 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 603.0
CMS2_k127_5196801_5 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 581.0
CMS2_k127_5196801_6 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 528.0
CMS2_k127_5196801_7 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 519.0
CMS2_k127_5196801_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 518.0
CMS2_k127_5196801_9 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 483.0
CMS2_k127_5200274_0 MerR HTH family regulatory protein - - - 0.000000000000000000000000000000000000000008821 157.0
CMS2_k127_5200274_1 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000005919 153.0
CMS2_k127_5200274_2 - - - - 0.00000000000000000000000000001148 121.0
CMS2_k127_5200274_3 YHS domain - - - 0.000000000000000000000000003919 116.0
CMS2_k127_5212807_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1560.0
CMS2_k127_5212807_1 Signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 382.0
CMS2_k127_5212807_2 diguanylate cyclase K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 310.0
CMS2_k127_5212807_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007992 256.0
CMS2_k127_5225329_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 4.938e-294 919.0
CMS2_k127_5225329_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 605.0
CMS2_k127_5225329_2 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 438.0
CMS2_k127_5225329_3 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000001886 237.0
CMS2_k127_5225329_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000000000000002308 179.0
CMS2_k127_5225329_5 RDD family - - - 0.0000000000000000000000000000000000000000000004518 170.0
CMS2_k127_5230631_0 fumarate reductase, flavoprotein subunit K00244 - 1.3.5.4 0.0 1053.0
CMS2_k127_5230631_1 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1024.0
CMS2_k127_5230631_10 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 316.0
CMS2_k127_5230631_11 fumarate reductase K00246 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 318.0
CMS2_k127_5230631_12 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 303.0
CMS2_k127_5230631_13 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001555 291.0
CMS2_k127_5230631_14 COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit - - - 0.0000000000000000000000000000000000000000000000000006413 198.0
CMS2_k127_5230631_15 Cytochrome c - - - 0.0000000000000000000000000000000000000000006158 160.0
CMS2_k127_5230631_16 MiaB-like tRNA modifying enzyme - - - 0.00000000000000000000000000000000000001378 147.0
CMS2_k127_5230631_17 - - - - 0.000000000000000000000000000000003843 136.0
CMS2_k127_5230631_18 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000003727 104.0
CMS2_k127_5230631_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 9.974e-200 627.0
CMS2_k127_5230631_3 Belongs to the AAA ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 552.0
CMS2_k127_5230631_4 Heterodisulfide reductase subunit B K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 496.0
CMS2_k127_5230631_5 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 481.0
CMS2_k127_5230631_6 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 437.0
CMS2_k127_5230631_7 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 405.0
CMS2_k127_5230631_8 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 384.0
CMS2_k127_5230631_9 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 340.0
CMS2_k127_5230932_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.009e-195 616.0
CMS2_k127_5230932_1 phosphate transporter K03306 - - 1.128e-195 624.0
CMS2_k127_5230932_10 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 369.0
CMS2_k127_5230932_11 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 334.0
CMS2_k127_5230932_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 286.0
CMS2_k127_5230932_13 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 291.0
CMS2_k127_5230932_14 DNA replication regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003333 267.0
CMS2_k127_5230932_15 DNA processing protein K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003157 263.0
CMS2_k127_5230932_16 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000005408 239.0
CMS2_k127_5230932_17 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000407 230.0
CMS2_k127_5230932_18 - - - - 0.0000000000000000000000000000000000000000000000000278 186.0
CMS2_k127_5230932_19 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000005916 184.0
CMS2_k127_5230932_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 585.0
CMS2_k127_5230932_20 Belongs to the bacterial histone-like protein family K03530 - - 0.000000000000000000000000000000000000000000001124 166.0
CMS2_k127_5230932_21 - - - - 0.00000000000000000000000000000000000000000002076 168.0
CMS2_k127_5230932_22 proteins homologs of microcin C7 resistance protein MccF - - - 0.0000000000000000000000000000000000000001261 156.0
CMS2_k127_5230932_23 DNA-binding protein - - - 0.00000000000000000000000000005333 117.0
CMS2_k127_5230932_24 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000001685 120.0
CMS2_k127_5230932_26 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.0000000000000000000003692 97.0
CMS2_k127_5230932_27 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000003832 87.0
CMS2_k127_5230932_28 - - - - 0.00000000000001116 87.0
CMS2_k127_5230932_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 483.0
CMS2_k127_5230932_4 dihydropteroate synthase K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 471.0
CMS2_k127_5230932_5 Belongs to the agmatine deiminase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 445.0
CMS2_k127_5230932_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 442.0
CMS2_k127_5230932_7 Belongs to the ParA family K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 414.0
CMS2_k127_5230932_8 Flagellar Assembly Protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 429.0
CMS2_k127_5230932_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 363.0
CMS2_k127_5242496_0 Chemotaxis phosphatase CheX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 606.0
CMS2_k127_5242496_1 Potassium channel protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 563.0
CMS2_k127_5242496_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 372.0
CMS2_k127_5242496_3 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 298.0
CMS2_k127_5242496_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000002168 112.0
CMS2_k127_5242496_5 biopolymer transport protein K03559 - - 0.000000000000101 71.0
CMS2_k127_5252114_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1117.0
CMS2_k127_5252114_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.639e-254 794.0
CMS2_k127_5252114_10 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000000003299 180.0
CMS2_k127_5252114_11 COGs COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.0000000000000000000000000000000002667 132.0
CMS2_k127_5252114_12 membrane - - - 0.000000000000000000000001453 106.0
CMS2_k127_5252114_13 - - - - 0.0000000000004242 69.0
CMS2_k127_5252114_2 Pyridine nucleotide-disulfide oxidoreductase K05910 - 1.11.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 557.0
CMS2_k127_5252114_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 527.0
CMS2_k127_5252114_4 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 513.0
CMS2_k127_5252114_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 360.0
CMS2_k127_5252114_6 Membrane protease subunits - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 361.0
CMS2_k127_5252114_7 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 362.0
CMS2_k127_5252114_8 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 358.0
CMS2_k127_5252114_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 302.0
CMS2_k127_5286112_0 DNA polymerase III K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 351.0
CMS2_k127_5286112_1 Ribonuclease K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 295.0
CMS2_k127_5286112_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000000001928 239.0
CMS2_k127_5286112_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000001744 165.0
CMS2_k127_5286112_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000002953 144.0
CMS2_k127_5286112_5 Ankyrin repeats (3 copies) K08852,K15502 - 2.7.11.1 0.0006633 47.0
CMS2_k127_5323656_0 phosphorylase kinase alphabeta K07190 - - 0.0 1499.0
CMS2_k127_5323656_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1045.0
CMS2_k127_5323656_10 PFAM Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 458.0
CMS2_k127_5323656_11 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 435.0
CMS2_k127_5323656_12 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 430.0
CMS2_k127_5323656_13 component of anaerobic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 292.0
CMS2_k127_5323656_14 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006897 271.0
CMS2_k127_5323656_15 - - - - 0.00000000000000000000000000000000000000000000000000008251 190.0
CMS2_k127_5323656_16 Heme iron utilization protein K07226 - - 0.000000000000000000000000000000000000000000000000002664 186.0
CMS2_k127_5323656_17 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000002214 180.0
CMS2_k127_5323656_18 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000005858 173.0
CMS2_k127_5323656_19 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000007689 154.0
CMS2_k127_5323656_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.035e-298 925.0
CMS2_k127_5323656_20 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.00000000000000000000000000000000000002985 154.0
CMS2_k127_5323656_21 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000004258 67.0
CMS2_k127_5323656_22 Glutaredoxin - - - 0.00000819 53.0
CMS2_k127_5323656_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.32e-272 841.0
CMS2_k127_5323656_4 diguanylate cyclase - - - 3.197e-256 802.0
CMS2_k127_5323656_5 COG1070 Sugar (pentulose and hexulose) K11216 - 2.7.1.189 6.853e-217 684.0
CMS2_k127_5323656_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 5.621e-212 662.0
CMS2_k127_5323656_7 sulfate adenylyltransferase K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 582.0
CMS2_k127_5323656_8 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 493.0
CMS2_k127_5323656_9 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 482.0
CMS2_k127_5324750_0 peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 491.0
CMS2_k127_5324750_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 455.0
CMS2_k127_5324750_10 Protein of unknown function (DUF3568) - - - 0.000000005943 63.0
CMS2_k127_5324750_2 Dipeptidase K01270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 378.0
CMS2_k127_5324750_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 339.0
CMS2_k127_5324750_4 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 301.0
CMS2_k127_5324750_5 Nudix domain K08077 - 3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000007722 246.0
CMS2_k127_5324750_6 Formylmethanofuran dehydrogenase, subunit e - - - 0.00000000000000000000000000000000000000000000000000000000000007606 218.0
CMS2_k127_5324750_7 Plasminogen-binding protein pgbA N-terminal - - - 0.000000000000000000000000000000000000000000000000000000001001 211.0
CMS2_k127_5324750_8 Glycolate oxidase subunit K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000004186 188.0
CMS2_k127_5324750_9 - - - - 0.000000000000006771 77.0
CMS2_k127_5327849_0 PFAM TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 484.0
CMS2_k127_5327849_1 - - - - 0.000000000002695 74.0
CMS2_k127_5332960_0 Abc transporter K02035 - - 1.749e-212 670.0
CMS2_k127_5332960_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 349.0
CMS2_k127_5332960_2 pyruvate ferredoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 307.0
CMS2_k127_5332960_3 Hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005316 281.0
CMS2_k127_5332960_4 carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000004605 236.0
CMS2_k127_5332960_5 pyruvate ferredoxin oxidoreductase K00171 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000002969 227.0
CMS2_k127_5346774_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000302 183.0
CMS2_k127_5346774_2 Belongs to the glucose-6-phosphate 1-epimerase family K01792 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 5.1.3.15 0.00000000000000000000002785 100.0
CMS2_k127_5354786_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 6.495e-202 634.0
CMS2_k127_5354786_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 602.0
CMS2_k127_5354786_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 402.0
CMS2_k127_5354786_3 permease K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 376.0
CMS2_k127_5354786_4 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 374.0
CMS2_k127_5354786_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001471 263.0
CMS2_k127_5354786_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000004477 256.0
CMS2_k127_5367966_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.154e-283 874.0
CMS2_k127_5367966_1 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 602.0
CMS2_k127_5367966_2 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000000000000000000000000002969 146.0
CMS2_k127_5393418_0 Sulfatase - - - 1.621e-215 687.0
CMS2_k127_5393418_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.348e-208 656.0
CMS2_k127_5393418_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 404.0
CMS2_k127_5393418_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000002652 241.0
CMS2_k127_5393418_4 PFAM Ferric reductase domain protein transmembrane component domain K17247 - - 0.000000000000000000000000000000000000000005705 161.0
CMS2_k127_541670_0 Belongs to the UbiD family K03182 - 4.1.1.98 1.434e-299 927.0
CMS2_k127_541670_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.183e-262 818.0
CMS2_k127_541670_10 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000008365 224.0
CMS2_k127_541670_11 -acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000005157 205.0
CMS2_k127_541670_12 Domain of unknown function (DUF386) - - - 0.00000000000000000000000000000000000000000000000000000008739 201.0
CMS2_k127_541670_13 phospholipase K01058 - 3.1.1.32,3.1.1.4 0.000000000000000000000000000000000000000000000000001014 189.0
CMS2_k127_541670_14 - - - - 0.00000000000000000000000000000000002431 143.0
CMS2_k127_541670_15 - - - - 0.00000000000000000000000000000000007609 136.0
CMS2_k127_541670_17 Protein of unknown function (DUF504) - - - 0.000000000000000000000008473 103.0
CMS2_k127_541670_18 Domain of unknown function (DUF2018) - - - 0.00000000000000000000007406 101.0
CMS2_k127_541670_19 - - - - 0.0000000000000000001012 93.0
CMS2_k127_541670_2 Belongs to the DEAD box helicase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 614.0
CMS2_k127_541670_20 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000001136 88.0
CMS2_k127_541670_21 Domain of unknown function (DUF4136) - - - 0.00000000000000003796 89.0
CMS2_k127_541670_22 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000009001 77.0
CMS2_k127_541670_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 479.0
CMS2_k127_541670_4 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 429.0
CMS2_k127_541670_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 417.0
CMS2_k127_541670_6 NnrU protein K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 396.0
CMS2_k127_541670_7 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 347.0
CMS2_k127_541670_8 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 334.0
CMS2_k127_541670_9 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 295.0
CMS2_k127_5421115_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1836.0
CMS2_k127_5421115_1 rod shape-determining protein mreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 606.0
CMS2_k127_5421115_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003575 269.0
CMS2_k127_5421115_3 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000003214 231.0
CMS2_k127_5421115_4 - - - - 0.000000000000000000000000000000000000000000000000005027 184.0
CMS2_k127_5421115_5 L-threonylcarbamoyladenylate synthase - - - 0.0000000000000000000000000000000000000002022 154.0
CMS2_k127_5421115_6 - - - - 0.000000000000000000000000000007885 124.0
CMS2_k127_5424668_0 Histidine kinase - - - 0.0 1144.0
CMS2_k127_5424668_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000008617 192.0
CMS2_k127_5424668_2 Response regulator receiver K07814 - - 0.0000000000000000000000000000000000000000000000009226 176.0
CMS2_k127_5424766_0 Putative diguanylate phosphodiesterase - - - 2.533e-283 882.0
CMS2_k127_5424766_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 451.0
CMS2_k127_5424766_2 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 393.0
CMS2_k127_5424766_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000001459 206.0
CMS2_k127_542533_0 Molecular chaperone. Has ATPase activity K04079 - - 5.338e-314 971.0
CMS2_k127_542533_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 572.0
CMS2_k127_542533_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000003232 188.0
CMS2_k127_542533_11 response regulator, receiver K02479 - - 0.00000000000000000000000006363 115.0
CMS2_k127_542533_12 - - - - 0.0000000000000000007006 96.0
CMS2_k127_542533_13 COG0642 Signal transduction histidine kinase - - - 0.000000004514 64.0
CMS2_k127_542533_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 535.0
CMS2_k127_542533_3 Permease, YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 326.0
CMS2_k127_542533_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 316.0
CMS2_k127_542533_5 Peptidase A24 K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004281 279.0
CMS2_k127_542533_6 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001214 271.0
CMS2_k127_542533_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000001477 249.0
CMS2_k127_542533_8 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000001264 252.0
CMS2_k127_542533_9 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000002321 232.0
CMS2_k127_5465049_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.708e-232 730.0
CMS2_k127_5465049_1 2-nitropropane dioxygenase K00459 - 1.13.12.16 4.715e-204 638.0
CMS2_k127_5465049_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 603.0
CMS2_k127_5465049_3 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 419.0
CMS2_k127_5465049_4 Protein conserved in bacteria - - - 0.0000000000000000008374 91.0
CMS2_k127_5543526_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 535.0
CMS2_k127_5543526_1 hmm pf00563 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 418.0
CMS2_k127_5543526_10 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000003487 72.0
CMS2_k127_5543526_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 367.0
CMS2_k127_5543526_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 372.0
CMS2_k127_5543526_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 286.0
CMS2_k127_5543526_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000006079 235.0
CMS2_k127_5543526_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000003159 212.0
CMS2_k127_5543526_7 ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000371 186.0
CMS2_k127_5543526_8 - - - - 0.000000000000000000000000000000000000000004859 161.0
CMS2_k127_5543526_9 Nitrogen fixation protein NifU - - - 0.0000000000000000000000000000000000000001574 151.0
CMS2_k127_5567827_0 Pseudouridine synthase K06177,K06179,K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 325.0
CMS2_k127_5567827_1 G T U mismatch-specific DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000001048 230.0
CMS2_k127_5567827_2 NLP P60 protein K13694,K13695 - 3.4.17.13 0.0000000000000000000000000000000000000000000467 164.0
CMS2_k127_5567827_3 COG0564 Pseudouridylate synthases, 23S RNA-specific K06175 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.26 0.000000000000000000000000000000000000000105 154.0
CMS2_k127_5567827_4 - - - - 0.00000000000000000000000000000001792 130.0
CMS2_k127_5567827_5 - K06950 - - 0.000000000001305 70.0
CMS2_k127_5720126_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 474.0
CMS2_k127_5720126_1 Transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 337.0
CMS2_k127_5720126_2 flagellar - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001819 265.0
CMS2_k127_5720126_3 Protein of unknown function (DUF3584) - - - 0.000000000000000000000000000000000000000000000000001301 200.0
CMS2_k127_5720126_4 flagellar motor switch protein K02417 - - 0.000000000000000000000000000000000000000000001262 167.0
CMS2_k127_5720126_5 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000866 121.0
CMS2_k127_5720126_7 membrane transporter protein K07090 - - 0.00000000000000000001407 92.0
CMS2_k127_5790731_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 3.391e-206 654.0
CMS2_k127_5790731_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 589.0
CMS2_k127_5790731_2 a g-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 381.0
CMS2_k127_5790731_3 Jag_N K06346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006622 284.0
CMS2_k127_5790731_4 hmm pf01205 - - - 0.00000000000000000000000000000000000000000000000000000000000001875 222.0
CMS2_k127_5790731_5 Could be involved in insertion of integral membrane proteins into the membrane - - - 0.000000000000000000000000000000000000009459 147.0
CMS2_k127_5790731_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000002064 109.0
CMS2_k127_5790731_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000001084 79.0
CMS2_k127_5794674_0 Abc transporter K06158 - - 6.672e-296 917.0
CMS2_k127_5794674_1 chemotaxis protein K03406 - - 4.739e-208 659.0
CMS2_k127_5794674_2 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 318.0
CMS2_k127_5794674_3 COG1734 DnaK suppressor protein K06204 - - 0.0000000000000000000000000000000000000324 147.0
CMS2_k127_5794674_4 - - - - 0.000000000000000000000000000008944 120.0
CMS2_k127_5794674_5 - - - - 0.00000000000000000000000518 111.0
CMS2_k127_5794674_6 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.00000000000004773 76.0
CMS2_k127_5806914_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 3.608e-212 670.0
CMS2_k127_5806914_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 544.0
CMS2_k127_5806914_10 LPP20 lipoprotein - - - 0.000000000000000000000000000000000000000000000000000002672 196.0
CMS2_k127_5806914_11 signal transduction sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000002034 183.0
CMS2_k127_5806914_12 LPP20 lipoprotein - - - 0.000000000000000000005526 106.0
CMS2_k127_5806914_13 - - - - 0.000000000000000006146 85.0
CMS2_k127_5806914_14 - - - - 0.00000000000006029 77.0
CMS2_k127_5806914_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 497.0
CMS2_k127_5806914_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 483.0
CMS2_k127_5806914_4 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 349.0
CMS2_k127_5806914_5 Membrane-bound lytic murein transglycosylase C K08306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005661 278.0
CMS2_k127_5806914_6 hmm pf00563 - - - 0.000000000000000000000000000000000000000000000000000000000000000004946 253.0
CMS2_k127_5806914_7 - - - - 0.0000000000000000000000000000000000000000000000000000000002122 215.0
CMS2_k127_5806914_8 phosphoribosyltransferase K00769 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000006403 206.0
CMS2_k127_5806914_9 Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000000000000000000000000000000000000002354 194.0
CMS2_k127_5812536_0 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 298.0
CMS2_k127_5812536_1 riboflavin synthase alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 294.0
CMS2_k127_5812536_2 - - - - 0.000000000000000000000000000000000002426 143.0
CMS2_k127_5812536_3 - - - - 0.0000000000000000000000000002769 118.0
CMS2_k127_5812536_4 of the cytoplasmic domain of flagellar protein FhlB K04061 - - 0.000000000000000000000002737 105.0
CMS2_k127_5812536_5 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 - 4.4.1.21 0.00000000000001152 74.0
CMS2_k127_5833887_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1149.0
CMS2_k127_5833887_1 Protein of unknown function DUF115 - - - 3.208e-244 772.0
CMS2_k127_5833887_10 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 364.0
CMS2_k127_5833887_11 acid synthase K01654,K15898 - 2.5.1.56,2.5.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000004782 248.0
CMS2_k127_5833887_12 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000001386 231.0
CMS2_k127_5833887_13 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000002698 167.0
CMS2_k127_5833887_14 AMIN domain - - - 0.00000000000000000000000000000000000000000004218 167.0
CMS2_k127_5833887_15 Flagellar biosynthetic protein FliQ K02420 - - 0.00000000000000000000000000000000001433 136.0
CMS2_k127_5833887_16 - - - - 0.000000000000000008087 87.0
CMS2_k127_5833887_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.148e-243 754.0
CMS2_k127_5833887_3 Protein of unknown function DUF115 - - - 1.606e-204 658.0
CMS2_k127_5833887_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 586.0
CMS2_k127_5833887_5 Protein of unknown function DUF115 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 487.0
CMS2_k127_5833887_6 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 450.0
CMS2_k127_5833887_7 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 445.0
CMS2_k127_5833887_8 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 428.0
CMS2_k127_5833887_9 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 377.0
CMS2_k127_5892161_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 4.686e-211 660.0
CMS2_k127_5892161_1 domain protein K09944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 601.0
CMS2_k127_5892161_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 423.0
CMS2_k127_5892161_3 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000002379 76.0
CMS2_k127_6049288_0 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 419.0
CMS2_k127_6049288_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000001136 129.0
CMS2_k127_6068189_0 - K07221 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 311.0
CMS2_k127_6068189_2 META domain K09914 - - 0.0000000000000008523 82.0
CMS2_k127_6105780_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.67e-310 956.0
CMS2_k127_6105780_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 6.963e-197 627.0
CMS2_k127_6105780_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 329.0
CMS2_k127_6105780_3 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 333.0
CMS2_k127_6105780_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 289.0
CMS2_k127_6105780_5 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000000000000000000008683 219.0
CMS2_k127_6105780_6 Preprotein translocase subunit SecG K03075 - - 0.000000000000000000000000000000000002362 140.0
CMS2_k127_6105780_7 Putative ATP-dependant zinc protease - - - 0.00000000000000000000000000004886 123.0
CMS2_k127_6148246_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 390.0
CMS2_k127_6148246_1 molybdopterin biosynthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009006 276.0
CMS2_k127_6148246_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009085 273.0
CMS2_k127_6148246_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000001209 265.0
CMS2_k127_6148246_4 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000009209 121.0
CMS2_k127_6148246_5 Protein conserved in bacteria - - - 0.0000000000003202 76.0
CMS2_k127_6181175_0 COGs COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 444.0
CMS2_k127_6181175_1 E1 component alpha subunit K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 425.0
CMS2_k127_6181175_2 PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 400.0
CMS2_k127_6181175_3 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 388.0
CMS2_k127_6181175_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 368.0
CMS2_k127_6181175_7 Resolvase, N terminal domain - - - 0.0000598 46.0
CMS2_k127_6188455_0 Radical SAM - - - 8.661e-227 712.0
CMS2_k127_6188455_1 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 424.0
CMS2_k127_6188455_10 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001522 248.0
CMS2_k127_6188455_11 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000004859 224.0
CMS2_k127_6188455_12 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000001062 208.0
CMS2_k127_6188455_13 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000001064 216.0
CMS2_k127_6188455_14 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000000000269 207.0
CMS2_k127_6188455_15 a g-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000001383 200.0
CMS2_k127_6188455_16 - - - - 0.0000000000000000000000000000000000000000000007923 180.0
CMS2_k127_6188455_17 Response regulator receiver K07814 - - 0.000000000000000000000000000000000000000002608 158.0
CMS2_k127_6188455_18 - - - - 0.0000000000000000000000000000000000007778 143.0
CMS2_k127_6188455_19 Chorismate mutase K04782 - 4.2.99.21 0.00000000000000000000000000000000858 129.0
CMS2_k127_6188455_2 Belongs to the TtcA family K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 413.0
CMS2_k127_6188455_20 Rhodanese-like domain - - - 0.00000000000000000000000001325 114.0
CMS2_k127_6188455_3 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 404.0
CMS2_k127_6188455_4 coproporphyrinogen III oxidase K00228 GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 378.0
CMS2_k127_6188455_5 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002905 280.0
CMS2_k127_6188455_6 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000104 259.0
CMS2_k127_6188455_7 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K18284 - 3.2.2.30,3.2.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001512 257.0
CMS2_k127_6188455_8 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005713 253.0
CMS2_k127_6188455_9 Dtw domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007957 248.0
CMS2_k127_6188878_0 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 421.0
CMS2_k127_6188878_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 336.0
CMS2_k127_6188878_2 FIST N domain - - - 0.0000000000000000000000000000000000000000000008627 192.0
CMS2_k127_6270555_0 Cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 608.0
CMS2_k127_6270555_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 593.0
CMS2_k127_6270555_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000001637 210.0
CMS2_k127_6270555_11 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000000000000000000000005543 183.0
CMS2_k127_6270555_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000002069 164.0
CMS2_k127_6270555_13 - - - - 0.00000000000000000000000000000000000000007051 158.0
CMS2_k127_6270555_14 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000001089 159.0
CMS2_k127_6270555_15 - - - - 0.0000000000000000000002858 98.0
CMS2_k127_6270555_16 thiamine biosynthesis protein ThiS K03154 - - 0.000000000000000002048 86.0
CMS2_k127_6270555_17 - - - - 0.000000000000001559 80.0
CMS2_k127_6270555_18 transport system auxiliary component K18480 - - 0.00000000000001022 82.0
CMS2_k127_6270555_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 477.0
CMS2_k127_6270555_3 Response regulator receiver K03415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 446.0
CMS2_k127_6270555_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 366.0
CMS2_k127_6270555_5 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 349.0
CMS2_k127_6270555_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 330.0
CMS2_k127_6270555_7 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 299.0
CMS2_k127_6270555_8 abc transporter atp-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006733 280.0
CMS2_k127_6270555_9 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003412 252.0
CMS2_k127_6276973_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K16881 - 2.7.7.13,5.4.2.8 0.0 1360.0
CMS2_k127_6276973_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1191.0
CMS2_k127_6276973_10 Belongs to the HypD family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 597.0
CMS2_k127_6276973_11 hydrogenase expression formation protein K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 490.0
CMS2_k127_6276973_12 Hydrogenase K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 445.0
CMS2_k127_6276973_13 Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 386.0
CMS2_k127_6276973_14 Hydrogenase, large subunit K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 394.0
CMS2_k127_6276973_15 PFAM NADH ubiquinone oxidoreductase, 20 Kd subunit K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 312.0
CMS2_k127_6276973_16 Family of unknown function (DUF695) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 303.0
CMS2_k127_6276973_17 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 298.0
CMS2_k127_6276973_18 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005591 280.0
CMS2_k127_6276973_19 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002839 253.0
CMS2_k127_6276973_2 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1106.0
CMS2_k127_6276973_20 hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000000000000000000000000000002621 240.0
CMS2_k127_6276973_21 hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000000000000000000000000003841 231.0
CMS2_k127_6276973_22 PFAM Galactose-1-phosphate uridyl transferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000002321 218.0
CMS2_k127_6276973_23 Enoyl-CoA hydratase/isomerase K19640 - - 0.0000000000000000000000000000000000000000000000001651 178.0
CMS2_k127_6276973_24 HypF finger - - - 0.00000000000000000000000000000000000000003274 173.0
CMS2_k127_6276973_25 hydrogenase assembly chaperone HypC K04653 - - 0.00000000000000000000000000000000000007253 144.0
CMS2_k127_6276973_26 - - - - 0.0000000000000000000000000000000000002578 141.0
CMS2_k127_6276973_3 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0 1103.0
CMS2_k127_6276973_4 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 0.0 1099.0
CMS2_k127_6276973_5 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 2.822e-269 848.0
CMS2_k127_6276973_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 5.611e-263 816.0
CMS2_k127_6276973_7 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.453e-250 777.0
CMS2_k127_6276973_8 Small subunit K05927 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.5.1 1.548e-243 756.0
CMS2_k127_6276973_9 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 5.773e-198 631.0
CMS2_k127_6310160_0 Mitochondrial degradasome RNA helicase subunit C terminal K17675 - 3.6.4.13 2.213e-220 696.0
CMS2_k127_6310160_1 chemotaxis protein - - - 2.553e-196 631.0
CMS2_k127_6310160_2 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 449.0
CMS2_k127_6310160_3 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 398.0
CMS2_k127_6310160_4 fumarate reductase, iron-sulfur protein K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 319.0
CMS2_k127_6310160_5 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000003361 221.0
CMS2_k127_6310160_6 - - - - 0.0000000000000001183 87.0
CMS2_k127_6317587_0 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 1.406e-245 770.0
CMS2_k127_6317587_1 biosynthesis protein K16554,K16692 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 554.0
CMS2_k127_6317587_2 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 338.0
CMS2_k127_6317587_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 311.0
CMS2_k127_6317587_4 COG4464 Capsular polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000006664 228.0
CMS2_k127_6317587_5 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000002178 230.0
CMS2_k127_6317587_6 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000002953 223.0
CMS2_k127_6317587_7 GlutRNAGln amidotransferase subunit D K01424 - 3.5.1.1 0.00000000000000000000000000000000000000001287 159.0
CMS2_k127_6317587_8 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000009313 153.0
CMS2_k127_6317587_9 antibiotic catabolic process - - - 0.0000000000000000000000372 109.0
CMS2_k127_6327171_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 470.0
CMS2_k127_6327171_1 component I K01665 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 391.0
CMS2_k127_6327171_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.00000000000000000000000000000000000000000000000000000001256 202.0
CMS2_k127_6334161_0 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 477.0
CMS2_k127_6334161_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 355.0
CMS2_k127_6334161_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 308.0
CMS2_k127_6334161_3 Belongs to the UPF0246 family K09861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001269 269.0
CMS2_k127_6334161_4 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.00000000000000000000000000000000002466 137.0
CMS2_k127_6334161_5 PFAM FecR protein - - - 0.0000000000000000000000000000002218 133.0
CMS2_k127_6334161_6 Thioredoxin - - - 0.00000000000000000000000000284 114.0
CMS2_k127_6334161_7 - - - - 0.000000000000005443 78.0
CMS2_k127_6367875_0 intermembrane lipid transfer K06192 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016020,GO:0016021,GO:0016043,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0071944,GO:0120009 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 604.0
CMS2_k127_6367875_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009918 274.0
CMS2_k127_6367875_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000009273 184.0
CMS2_k127_6367875_3 paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000006975 170.0
CMS2_k127_6367875_4 Paraquat-inducible protein A K03808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000007489 79.0
CMS2_k127_6645951_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1079.0
CMS2_k127_6645951_1 response regulator K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 342.0
CMS2_k127_6645951_2 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 343.0
CMS2_k127_6645951_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 344.0
CMS2_k127_6645951_4 methyltransferase K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000005264 188.0
CMS2_k127_6645951_5 protein-glutamate methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000003256 147.0
CMS2_k127_6645951_6 Methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000002448 132.0
CMS2_k127_6645951_7 outer membrane porin, OprD family - - - 0.000000000000000000000000005588 113.0
CMS2_k127_6645951_8 iron ion homeostasis K04758 - - 0.0000000000000000001031 91.0
CMS2_k127_665737_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 5.781e-235 739.0
CMS2_k127_665737_1 abc transporter atp-binding protein K02031,K15587 - 3.6.3.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 307.0
CMS2_k127_665737_2 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.00000007742 54.0
CMS2_k127_6801411_0 Phospholipid glycerol acyltransferase - - - 4.029e-238 749.0
CMS2_k127_6801411_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 569.0
CMS2_k127_6801411_2 Cytochrome K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 501.0
CMS2_k127_6801411_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 458.0
CMS2_k127_6801411_4 Desulfoferrodoxin, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 339.0
CMS2_k127_6801411_5 phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 302.0
CMS2_k127_6801411_6 Belongs to the pseudouridine synthase RluA family K06180 - 5.4.99.23 0.000000000000000000000000000000000002044 140.0
CMS2_k127_6801411_7 - - - - 0.000001232 54.0
CMS2_k127_76392_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 351.0
CMS2_k127_76392_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 357.0
CMS2_k127_76392_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000213 299.0
CMS2_k127_775605_0 Major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 372.0
CMS2_k127_775605_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 282.0
CMS2_k127_775605_2 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000431 229.0
CMS2_k127_775605_3 RDD family - - - 0.00000000000000000000000000001367 124.0
CMS2_k127_81937_0 Sulfate permease family - - - 7.192e-228 716.0
CMS2_k127_81937_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 332.0
CMS2_k127_81937_2 ATPase (AAA K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 290.0