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Overview

ID MAG00495
Name CMS3_bin.126
Sample SMP0012
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Rhodocyclaceae
Genus
Species
Assembly information
Completeness (%) 55.08
Contamination (%) 0.72
GC content (%) 66.0
N50 (bp) 9,573
Genome size (bp) 1,913,109

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1942

Gene name Description KEGG GOs EC E-value Score Sequence
CMS3_k127_1020124_0 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 507.0
CMS3_k127_1020124_1 hydroperoxide reductase activity K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004371 243.0
CMS3_k127_1052858_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 449.0
CMS3_k127_1052858_1 guanyl-nucleotide exchange factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 307.0
CMS3_k127_1052858_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000001704 75.0
CMS3_k127_1087739_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K11959 - - 1.122e-251 778.0
CMS3_k127_1087739_1 Belongs to the binding-protein-dependent transport system permease family K11960 - - 2.12e-201 639.0
CMS3_k127_1087739_2 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 603.0
CMS3_k127_1087739_3 Urea ABC transporter ATP-binding protein urtd K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 428.0
CMS3_k127_1087739_4 ABC transporter, ATP-binding protein K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 353.0
CMS3_k127_1087739_5 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 301.0
CMS3_k127_1087739_6 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.00000000000000000000000000000000000000000000000003684 180.0
CMS3_k127_1087739_7 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.00000000000000000000000000000000002018 136.0
CMS3_k127_1106162_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 7.834e-266 823.0
CMS3_k127_1106162_1 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 521.0
CMS3_k127_1106162_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 412.0
CMS3_k127_1106162_3 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 387.0
CMS3_k127_1106162_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000005608 255.0
CMS3_k127_1106162_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000000004757 211.0
CMS3_k127_1106162_6 TIGRFAM MJ0042 family finger-like protein - - - 0.00000000000000000000000000000000000000000000000001487 192.0
CMS3_k127_1113533_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 2.869e-194 608.0
CMS3_k127_1113533_1 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 5.659e-194 629.0
CMS3_k127_1113533_2 Enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 376.0
CMS3_k127_1113533_3 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000001151 218.0
CMS3_k127_1135907_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1718.0
CMS3_k127_1135907_1 Citrate transporter - - - 1.517e-259 815.0
CMS3_k127_1135907_10 COG0471 Di- and tricarboxylate transporters - - - 0.0000000000000000000000000000000000000000000000000000000000007662 218.0
CMS3_k127_1135907_11 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000837 154.0
CMS3_k127_1135907_12 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000000008783 95.0
CMS3_k127_1135907_13 COG0471 Di- and tricarboxylate transporters - - - 0.00000000000000001386 89.0
CMS3_k127_1135907_14 Chemoreceptor zinc-binding domain - - - 0.00000000000000004151 90.0
CMS3_k127_1135907_2 Sulfate transporter antisigma-factor antagonist STAS - - - 2.628e-242 769.0
CMS3_k127_1135907_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 524.0
CMS3_k127_1135907_4 4Fe-4S binding domain K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 475.0
CMS3_k127_1135907_5 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 434.0
CMS3_k127_1135907_6 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 427.0
CMS3_k127_1135907_7 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 353.0
CMS3_k127_1135907_8 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002188 266.0
CMS3_k127_1135907_9 Bacterial regulatory proteins, luxR family K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001593 255.0
CMS3_k127_1155253_0 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004634 277.0
CMS3_k127_1155253_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000252 204.0
CMS3_k127_1164077_0 fad dependent oxidoreductase K07137 - - 2.077e-247 773.0
CMS3_k127_1164077_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 592.0
CMS3_k127_1164077_10 - - - - 0.0000000000003169 76.0
CMS3_k127_1164077_11 - - - - 0.00005104 51.0
CMS3_k127_1164077_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 411.0
CMS3_k127_1164077_3 integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 350.0
CMS3_k127_1164077_4 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 333.0
CMS3_k127_1164077_5 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 293.0
CMS3_k127_1164077_6 Glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000002405 215.0
CMS3_k127_1164077_7 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000003581 171.0
CMS3_k127_1164077_8 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000002191 123.0
CMS3_k127_1164077_9 Winged helix-turn helix K07497 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000003556 76.0
CMS3_k127_12025_0 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 438.0
CMS3_k127_12025_1 squalene-associated FAD-dependent desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 411.0
CMS3_k127_12025_2 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 388.0
CMS3_k127_12025_3 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 301.0
CMS3_k127_12025_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002084 258.0
CMS3_k127_12025_5 COG0075 serine-pyruvate aminotransferase archaeal aspartate aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009518 248.0
CMS3_k127_12025_7 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000006042 220.0
CMS3_k127_12025_8 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000623 215.0
CMS3_k127_12025_9 phytoene K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000002444 116.0
CMS3_k127_1207873_0 Translation, ribosomal structure and biogenesis K08301 - - 1.081e-246 768.0
CMS3_k127_1207873_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 305.0
CMS3_k127_1207873_10 - - - - 0.00000000000000000000000000000000911 141.0
CMS3_k127_1207873_11 - - - - 0.000000000000000000000000003286 122.0
CMS3_k127_1207873_12 oxygen carrier activity K03406,K07216 - - 0.00000000000000000000000008366 111.0
CMS3_k127_1207873_13 Domain of unknown function (DUF1840) - - - 0.00000000000000001974 86.0
CMS3_k127_1207873_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000005585 71.0
CMS3_k127_1207873_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001744 264.0
CMS3_k127_1207873_3 Signal transduction protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004266 259.0
CMS3_k127_1207873_4 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001947 245.0
CMS3_k127_1207873_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001947 245.0
CMS3_k127_1207873_6 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000003808 227.0
CMS3_k127_1207873_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000003202 201.0
CMS3_k127_1207873_8 - - - - 0.000000000000000000000000000000000000000000000000001543 192.0
CMS3_k127_1207873_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000001186 171.0
CMS3_k127_1208849_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 5.132e-274 860.0
CMS3_k127_1208849_1 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 486.0
CMS3_k127_1208849_2 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 444.0
CMS3_k127_1208849_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 397.0
CMS3_k127_1208849_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 381.0
CMS3_k127_1208849_5 Stress-induced protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 303.0
CMS3_k127_1208849_6 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 292.0
CMS3_k127_1208849_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006684 276.0
CMS3_k127_1208849_8 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000006131 264.0
CMS3_k127_1208849_9 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000001205 115.0
CMS3_k127_1212688_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1362.0
CMS3_k127_1212688_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1135.0
CMS3_k127_1212688_10 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000002132 147.0
CMS3_k127_1212688_11 FecR protein - - - 0.0000003012 62.0
CMS3_k127_1212688_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 565.0
CMS3_k127_1212688_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 541.0
CMS3_k127_1212688_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 489.0
CMS3_k127_1212688_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 365.0
CMS3_k127_1212688_6 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 311.0
CMS3_k127_1212688_7 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 291.0
CMS3_k127_1212688_8 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002814 254.0
CMS3_k127_1212688_9 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000004969 188.0
CMS3_k127_121602_0 Peptidoglycan-synthase activator LpoB K07337 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005167 252.0
CMS3_k127_121602_1 LPP20 lipoprotein - - - 0.00000000000000000000000000000001094 135.0
CMS3_k127_121602_2 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000000004799 124.0
CMS3_k127_121602_4 protein conserved in bacteria K09859 - - 0.0000002489 60.0
CMS3_k127_1238744_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 6.292e-277 866.0
CMS3_k127_1238744_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 473.0
CMS3_k127_1238744_2 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 402.0
CMS3_k127_1238744_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 324.0
CMS3_k127_1238744_4 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008978 259.0
CMS3_k127_1238744_5 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000001835 198.0
CMS3_k127_1238744_6 TPR repeat - - - 0.000000000000000000000008603 115.0
CMS3_k127_1238744_7 Type 4 fimbrial biogenesis protein K02666 - - 0.0006876 51.0
CMS3_k127_1239836_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 3.57e-225 704.0
CMS3_k127_1239836_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 608.0
CMS3_k127_1239836_10 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 333.0
CMS3_k127_1239836_11 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000000000000000001168 192.0
CMS3_k127_1239836_12 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00003024 47.0
CMS3_k127_1239836_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 612.0
CMS3_k127_1239836_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 566.0
CMS3_k127_1239836_4 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 554.0
CMS3_k127_1239836_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 522.0
CMS3_k127_1239836_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 471.0
CMS3_k127_1239836_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 457.0
CMS3_k127_1239836_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 451.0
CMS3_k127_1239836_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 443.0
CMS3_k127_1313549_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1022.0
CMS3_k127_1313549_1 Flagellar biosynthesis regulator FlhF K02404 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 428.0
CMS3_k127_1313549_2 Cellulose biosynthesis protein BcsQ K04562 - - 0.000000000000000000007737 96.0
CMS3_k127_1316031_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.372e-268 830.0
CMS3_k127_1316031_1 ABC-type sugar transport system periplasmic component K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 389.0
CMS3_k127_1316031_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 387.0
CMS3_k127_1316031_3 Phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 294.0
CMS3_k127_1316031_4 Acetyltransferase (GNAT) domain - - - 0.0008282 42.0
CMS3_k127_1330059_0 Peptidase family U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001032 267.0
CMS3_k127_1330059_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000312 270.0
CMS3_k127_1330059_2 OmpA-like transmembrane domain K03286 - - 0.000002366 57.0
CMS3_k127_135067_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1023.0
CMS3_k127_135067_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 559.0
CMS3_k127_135067_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 545.0
CMS3_k127_135067_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 493.0
CMS3_k127_135067_4 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 454.0
CMS3_k127_135067_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 289.0
CMS3_k127_135067_6 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 0.00000000000000000000000008267 121.0
CMS3_k127_140467_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 445.0
CMS3_k127_140467_1 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000000000000000000000000001607 216.0
CMS3_k127_140467_2 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000000000000000000000005149 215.0
CMS3_k127_1509402_0 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 409.0
CMS3_k127_1509402_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001894 283.0
CMS3_k127_1509402_2 cytochrome - - - 0.000000000000000000000006346 109.0
CMS3_k127_1515641_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1350.0
CMS3_k127_1515641_1 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 1.904e-292 907.0
CMS3_k127_1515641_2 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 486.0
CMS3_k127_1515641_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 377.0
CMS3_k127_1515641_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000001308 261.0
CMS3_k127_1515641_5 Pfam cytochrome c K17230 - - 0.00000000000000000000000000000033 132.0
CMS3_k127_1515641_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000001078 111.0
CMS3_k127_1588877_0 Malate synthase K01638 - 2.3.3.9 2.132e-318 978.0
CMS3_k127_1588877_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 2.654e-305 955.0
CMS3_k127_1588877_10 transcriptional - - - 0.00000000000000000000000000000000000000000000000001398 182.0
CMS3_k127_1588877_11 - - - - 0.00000000000000000000000000000000000000000002917 173.0
CMS3_k127_1588877_12 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000003491 108.0
CMS3_k127_1588877_13 divalent heavy-metal cations transporter K07238 - - 0.000000000000009225 78.0
CMS3_k127_1588877_14 - - - - 0.000007319 55.0
CMS3_k127_1588877_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 6.788e-278 856.0
CMS3_k127_1588877_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 591.0
CMS3_k127_1588877_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 466.0
CMS3_k127_1588877_5 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 326.0
CMS3_k127_1588877_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001194 276.0
CMS3_k127_1588877_7 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000001003 245.0
CMS3_k127_1588877_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000000004034 204.0
CMS3_k127_1588877_9 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000000000009085 189.0
CMS3_k127_1598797_0 PFAM AMP-dependent synthetase and ligase K00666 - - 3.584e-295 942.0
CMS3_k127_1598797_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 570.0
CMS3_k127_1598797_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 396.0
CMS3_k127_1598797_3 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 322.0
CMS3_k127_1598797_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002809 246.0
CMS3_k127_1598797_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000008928 214.0
CMS3_k127_1598797_6 Prokaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000005274 189.0
CMS3_k127_1598797_7 - - - - 0.0000000000000000000009745 107.0
CMS3_k127_1598797_8 Acid phosphatase homologues K19302 - 3.6.1.27 0.00005403 47.0
CMS3_k127_1663977_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 3.515e-240 751.0
CMS3_k127_1663977_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 499.0
CMS3_k127_1663977_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 326.0
CMS3_k127_1663977_3 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000001993 195.0
CMS3_k127_1663977_4 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000003933 179.0
CMS3_k127_1679965_0 AcyL-CoA dehydrogenase K06445 - - 0.0 1170.0
CMS3_k127_1679965_1 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.598e-288 906.0
CMS3_k127_1679965_10 cytochrome - - - 0.0000000000000000000000000000000000004715 148.0
CMS3_k127_1679965_11 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000003636 122.0
CMS3_k127_1679965_12 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.000000000000000000000000006911 111.0
CMS3_k127_1679965_13 helix_turn_helix, Lux Regulon - - - 0.000000000000000003787 93.0
CMS3_k127_1679965_14 - - - - 0.00000000005673 72.0
CMS3_k127_1679965_2 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 6.87e-262 820.0
CMS3_k127_1679965_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 2.293e-208 656.0
CMS3_k127_1679965_4 Long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 494.0
CMS3_k127_1679965_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 448.0
CMS3_k127_1679965_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 293.0
CMS3_k127_1679965_7 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000000000003018 225.0
CMS3_k127_1679965_8 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000000000000000000000000002019 190.0
CMS3_k127_1679965_9 PFAM Dihaem cytochrome c - - - 0.00000000000000000000000000000000000000000002981 168.0
CMS3_k127_1864112_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 439.0
CMS3_k127_1864112_1 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000007033 235.0
CMS3_k127_1864112_2 Rrf2 family transcriptional regulator, iron-sulfur cluster assembly K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000000491 231.0
CMS3_k127_1922272_0 peptidase, U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 555.0
CMS3_k127_1922272_1 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 433.0
CMS3_k127_1922272_2 lipid carrier protein - - - 0.0000000000000000000000000000000000000000000000000000002435 202.0
CMS3_k127_1922272_3 Methyltransferase FkbM domain - - - 0.000000000449 66.0
CMS3_k127_1922272_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000002405 54.0
CMS3_k127_1952750_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1090.0
CMS3_k127_1952750_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 9.965e-211 658.0
CMS3_k127_1952750_2 - - - - 0.000000001735 64.0
CMS3_k127_1958793_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1411.0
CMS3_k127_1958793_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1077.0
CMS3_k127_1958793_10 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 472.0
CMS3_k127_1958793_11 AFG1-like ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 475.0
CMS3_k127_1958793_12 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 357.0
CMS3_k127_1958793_13 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 309.0
CMS3_k127_1958793_14 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000000000000000000000000000000000002373 187.0
CMS3_k127_1958793_15 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000000000000000000000000000000001149 156.0
CMS3_k127_1958793_16 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000003391 134.0
CMS3_k127_1958793_17 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000002417 89.0
CMS3_k127_1958793_18 Bacterial SH3 domain - - - 0.000000217 62.0
CMS3_k127_1958793_2 Putative diguanylate phosphodiesterase - - - 2.5e-323 1010.0
CMS3_k127_1958793_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.687e-262 812.0
CMS3_k127_1958793_4 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.991e-236 739.0
CMS3_k127_1958793_5 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 3.006e-196 625.0
CMS3_k127_1958793_6 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 609.0
CMS3_k127_1958793_7 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 600.0
CMS3_k127_1958793_8 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 582.0
CMS3_k127_1958793_9 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 493.0
CMS3_k127_1976990_0 COG3666 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 472.0
CMS3_k127_1999344_0 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 313.0
CMS3_k127_1999344_1 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 295.0
CMS3_k127_1999344_2 - - - - 0.000000000005518 72.0
CMS3_k127_200829_0 Type II secretory pathway, component HofQ K02666 - - 0.00000000000000000000000000000000000000000000000000000000001226 210.0
CMS3_k127_200829_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000003829 181.0
CMS3_k127_200829_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000009675 160.0
CMS3_k127_2012423_0 transport systems, ATPase components K02056 - 3.6.3.17 6.634e-229 724.0
CMS3_k127_2012423_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 523.0
CMS3_k127_2012423_2 uracil DNA glycosylase K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000009238 210.0
CMS3_k127_2012423_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000001903 182.0
CMS3_k127_2039666_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 5.743e-233 725.0
CMS3_k127_2039666_1 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 346.0
CMS3_k127_2039666_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001093 231.0
CMS3_k127_2057816_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 7.279e-204 644.0
CMS3_k127_2057816_1 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 464.0
CMS3_k127_2057816_2 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000002622 172.0
CMS3_k127_2057816_3 transcriptional - - - 0.000000000000000000000000000000495 126.0
CMS3_k127_2063349_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 6.257e-201 636.0
CMS3_k127_209717_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1382.0
CMS3_k127_209717_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 3.165e-292 916.0
CMS3_k127_209717_2 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625 - 2.3.1.8 6.384e-239 745.0
CMS3_k127_209717_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 509.0
CMS3_k127_209717_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 439.0
CMS3_k127_209717_5 4Fe-4S single cluster domain K18006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000003106 231.0
CMS3_k127_2122853_0 Asparagine synthase K01953 - 6.3.5.4 3.126e-265 828.0
CMS3_k127_2122853_1 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 3.303e-244 764.0
CMS3_k127_2122853_10 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.10.2.2 0.00000000000000000000000000000000000000000000000000006149 205.0
CMS3_k127_2122853_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000006078 144.0
CMS3_k127_2122853_12 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000001987 108.0
CMS3_k127_2122853_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 8.872e-223 706.0
CMS3_k127_2122853_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 429.0
CMS3_k127_2122853_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 420.0
CMS3_k127_2122853_5 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008437 364.0
CMS3_k127_2122853_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 339.0
CMS3_k127_2122853_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 320.0
CMS3_k127_2122853_8 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004115 290.0
CMS3_k127_2122853_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000002834 236.0
CMS3_k127_2150472_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.637e-294 912.0
CMS3_k127_2150472_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 549.0
CMS3_k127_2150472_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 412.0
CMS3_k127_2150472_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001074 295.0
CMS3_k127_2150472_4 Protein of unknown function (DUF3305) - - - 0.00000000000000000000000000000000000000000000000000000008944 201.0
CMS3_k127_2150472_5 Chaperone protein TorD - - - 0.000000000000000000000000000000000000000000000000000003845 211.0
CMS3_k127_2150472_6 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000002932 148.0
CMS3_k127_2150472_7 Protein of unknown function (DUF3306) - - - 0.0000000000000000001107 95.0
CMS3_k127_2169156_0 Glycogen debranching enzyme, glucanotransferase domain K05341 - 2.4.1.4 7.684e-298 928.0
CMS3_k127_2169156_1 Glycosyl transferase, group 1 K00696 - 2.4.1.14 3.418e-296 926.0
CMS3_k127_2169156_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.744e-221 696.0
CMS3_k127_2169156_3 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 332.0
CMS3_k127_2169156_4 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 292.0
CMS3_k127_2169156_5 SpoIIAA-like - - - 0.00000000000000000000000000000000000000000000000001697 183.0
CMS3_k127_2169156_6 PFAM Carbohydrate purine kinase - - - 0.00000000000000000009802 92.0
CMS3_k127_2264143_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 4.903e-230 717.0
CMS3_k127_2264143_1 Hydroxyglutarate oxidase K15736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 548.0
CMS3_k127_2264143_2 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain K00101,K15054 - 1.1.2.3,1.1.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 414.0
CMS3_k127_2264143_3 helix_turn_helix isocitrate lyase regulation K05818 - - 0.00000000000000000000000000000000000000000000000000000000000000000002099 241.0
CMS3_k127_2264143_4 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000003926 237.0
CMS3_k127_2264143_5 Belongs to the DsbB family K03611 - - 0.0000000000000000000000000000000000000000000000005877 179.0
CMS3_k127_2264143_6 alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.0000000000000000000000003239 107.0
CMS3_k127_2300985_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 579.0
CMS3_k127_2300985_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 559.0
CMS3_k127_2300985_10 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.000000000000000003335 91.0
CMS3_k127_2300985_2 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 341.0
CMS3_k127_2300985_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 290.0
CMS3_k127_2300985_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000002922 250.0
CMS3_k127_2300985_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000007686 244.0
CMS3_k127_2300985_6 OmpA family K03640 - - 0.00000000000000000000000000000000000000000000003456 176.0
CMS3_k127_2300985_7 TonB C terminal K03646 - - 0.000000000000000000000000000000000000003248 159.0
CMS3_k127_2300985_8 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000001273 141.0
CMS3_k127_2300985_9 Tol-pal system-associated acyl-CoA thioesterase K07107 - - 0.00000000000000000000000000000001576 141.0
CMS3_k127_238144_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.462e-277 872.0
CMS3_k127_238144_1 Von Willebrand factor type A K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 499.0
CMS3_k127_238144_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 362.0
CMS3_k127_238144_3 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 346.0
CMS3_k127_238144_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 330.0
CMS3_k127_238144_5 CBS domain containing protein K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004514 260.0
CMS3_k127_238144_6 Domain of unknown function (DUF4131) K02238 - - 0.00000000000000000000000000000000000000000000000000000000000005362 220.0
CMS3_k127_238144_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000001661 75.0
CMS3_k127_2419311_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1112.0
CMS3_k127_2419311_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.162e-242 752.0
CMS3_k127_2419311_10 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009431 253.0
CMS3_k127_2419311_11 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000002119 264.0
CMS3_k127_2419311_12 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000007812 254.0
CMS3_k127_2419311_13 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000006526 239.0
CMS3_k127_2419311_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003562 230.0
CMS3_k127_2419311_15 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000001171 226.0
CMS3_k127_2419311_16 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000029 205.0
CMS3_k127_2419311_17 peptidase - - - 0.000000000000000000000000000000000000000000000000000000193 205.0
CMS3_k127_2419311_18 - - - - 0.0000000000000000000000000000000000000000000000001408 181.0
CMS3_k127_2419311_19 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000001634 172.0
CMS3_k127_2419311_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.169e-200 634.0
CMS3_k127_2419311_20 PFAM Ankyrin K10799 - 2.4.2.30 0.0000007749 61.0
CMS3_k127_2419311_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 607.0
CMS3_k127_2419311_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 481.0
CMS3_k127_2419311_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 446.0
CMS3_k127_2419311_6 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 434.0
CMS3_k127_2419311_7 Mg2 and Co2 transporter CorC K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 415.0
CMS3_k127_2419311_8 PhoH-like phosphate starvation-inducible protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 313.0
CMS3_k127_2419311_9 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002125 271.0
CMS3_k127_2439780_0 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 487.0
CMS3_k127_2439780_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 460.0
CMS3_k127_2439780_2 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009019 247.0
CMS3_k127_2439780_3 (Lipo)protein K07287 - - 0.0000000000000000000000000000000000000000000000000000000002236 213.0
CMS3_k127_2450017_0 Ligated ion channel L-glutamate- and glycine-binding site K10014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 388.0
CMS3_k127_2450017_1 Binding-protein-dependent transport system inner membrane component K10015,K10023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 341.0
CMS3_k127_2450017_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 330.0
CMS3_k127_2450017_3 ABC-type histidine transport system, ATPase component K10021 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002789 261.0
CMS3_k127_2450017_4 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003724 269.0
CMS3_k127_2474175_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 3.804e-265 822.0
CMS3_k127_2474175_1 Domain of unknown function (DUF3391) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 452.0
CMS3_k127_2474175_2 Diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 316.0
CMS3_k127_2474175_3 Electron transport protein SCO1 SenC K07152 - - 0.0006269 47.0
CMS3_k127_248689_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1399.0
CMS3_k127_248689_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 6.53e-307 949.0
CMS3_k127_248689_10 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 310.0
CMS3_k127_248689_11 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 314.0
CMS3_k127_248689_12 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000009261 185.0
CMS3_k127_248689_13 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000000004719 181.0
CMS3_k127_248689_14 RecB family exonuclease K01144 - 3.1.11.5 0.00000000000000000000746 94.0
CMS3_k127_248689_15 Lipopolysaccharide assembly protein A domain K08992 - - 0.0000000002904 67.0
CMS3_k127_248689_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 7.302e-275 859.0
CMS3_k127_248689_3 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 574.0
CMS3_k127_248689_4 Amino acid transport and metabolism K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 565.0
CMS3_k127_248689_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 485.0
CMS3_k127_248689_6 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 442.0
CMS3_k127_248689_7 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 418.0
CMS3_k127_248689_8 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 371.0
CMS3_k127_248689_9 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 341.0
CMS3_k127_2518719_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1316.0
CMS3_k127_2518719_1 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 444.0
CMS3_k127_2518719_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 423.0
CMS3_k127_2518719_3 Asparaginase, N-terminal K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000511 205.0
CMS3_k127_2518719_4 - - - - 0.0000254 55.0
CMS3_k127_2555062_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 1.363e-298 924.0
CMS3_k127_2555062_1 succinate dehydrogenase K00242 - - 0.0000003463 54.0
CMS3_k127_2556751_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB - - - 0.0 1170.0
CMS3_k127_2556751_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0 1130.0
CMS3_k127_2556751_10 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000003526 207.0
CMS3_k127_2556751_2 CHASE2 K01768 - 4.6.1.1 6.635e-304 948.0
CMS3_k127_2556751_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 4.59e-223 696.0
CMS3_k127_2556751_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 557.0
CMS3_k127_2556751_5 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 354.0
CMS3_k127_2556751_6 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 342.0
CMS3_k127_2556751_7 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 299.0
CMS3_k127_2556751_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009386 288.0
CMS3_k127_2578920_0 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 559.0
CMS3_k127_2578920_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 447.0
CMS3_k127_263393_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.56e-311 966.0
CMS3_k127_263393_1 Acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase Amino acid transport and metabolism Coenzyme metabolism K01652 - 2.2.1.6 7.647e-304 939.0
CMS3_k127_263393_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 398.0
CMS3_k127_263393_11 Permease YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 401.0
CMS3_k127_263393_12 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 348.0
CMS3_k127_263393_13 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 346.0
CMS3_k127_263393_14 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 315.0
CMS3_k127_263393_15 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 304.0
CMS3_k127_263393_16 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 304.0
CMS3_k127_263393_17 Acetolactate synthase small K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 289.0
CMS3_k127_263393_18 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005612 259.0
CMS3_k127_263393_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006097 255.0
CMS3_k127_263393_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.377e-276 856.0
CMS3_k127_263393_20 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000000007163 218.0
CMS3_k127_263393_21 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000008759 201.0
CMS3_k127_263393_22 SpoIIAA-like - - - 0.00000000000000000000000000000000000000000000000000003358 190.0
CMS3_k127_263393_23 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000001654 146.0
CMS3_k127_263393_24 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000002939 132.0
CMS3_k127_263393_25 RDD family - - - 0.00000000000000000000000000009443 126.0
CMS3_k127_263393_26 Predicted membrane protein (DUF2069) - - - 0.0000000000000000000000000004625 123.0
CMS3_k127_263393_27 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000002103 121.0
CMS3_k127_263393_28 Protein of unknown function (DUF3106) - - - 0.0000000000000000000003931 101.0
CMS3_k127_263393_29 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000009318 83.0
CMS3_k127_263393_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.445e-253 789.0
CMS3_k127_263393_30 Protein of unknown function (DUF3619) - - - 0.0000000000000003898 85.0
CMS3_k127_263393_31 - - - - 0.000000000000007886 81.0
CMS3_k127_263393_4 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 2.552e-204 640.0
CMS3_k127_263393_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 4.715e-203 635.0
CMS3_k127_263393_6 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 530.0
CMS3_k127_263393_7 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 470.0
CMS3_k127_263393_8 Permease YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 452.0
CMS3_k127_263393_9 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 435.0
CMS3_k127_2655774_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 548.0
CMS3_k127_2655774_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 464.0
CMS3_k127_2655774_10 STAS domain K07122 - - 0.0000000000127 73.0
CMS3_k127_2655774_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 398.0
CMS3_k127_2655774_3 ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 398.0
CMS3_k127_2655774_4 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 387.0
CMS3_k127_2655774_5 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008501 281.0
CMS3_k127_2655774_6 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000006658 229.0
CMS3_k127_2655774_7 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000001209 237.0
CMS3_k127_2655774_8 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000006818 229.0
CMS3_k127_2655774_9 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000002818 202.0
CMS3_k127_275455_0 Cysteine-rich domain - - - 1.09e-251 794.0
CMS3_k127_275455_1 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 340.0
CMS3_k127_275455_2 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000000000000008239 181.0
CMS3_k127_2764854_0 Nitrogenase component 1 type Oxidoreductase K02586 - 1.18.6.1 3.436e-313 960.0
CMS3_k127_2764854_1 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 548.0
CMS3_k127_2764854_2 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000004072 201.0
CMS3_k127_2777507_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 8.872e-229 723.0
CMS3_k127_2777507_1 GGDEF domain K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 565.0
CMS3_k127_2777507_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 548.0
CMS3_k127_2777507_3 metal-dependent phosphoesterases (PHP family) K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 363.0
CMS3_k127_2777507_4 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 323.0
CMS3_k127_2777507_5 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 288.0
CMS3_k127_2777507_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000001839 209.0
CMS3_k127_2780065_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 2.892e-303 940.0
CMS3_k127_2780065_1 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 8.249e-276 850.0
CMS3_k127_2780065_10 Queuosine biosynthesis protein K07568 - 2.4.99.17 0.00000000000002992 72.0
CMS3_k127_2780065_2 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 1.737e-263 822.0
CMS3_k127_2780065_3 Mur ligase, middle domain protein - - - 4.044e-223 712.0
CMS3_k127_2780065_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 2.89e-197 621.0
CMS3_k127_2780065_5 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 556.0
CMS3_k127_2780065_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 505.0
CMS3_k127_2780065_7 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000000000000000000001585 234.0
CMS3_k127_2780065_8 Preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000000000000001977 147.0
CMS3_k127_2780065_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000001806 127.0
CMS3_k127_2808205_0 breast cancer carboxy-terminal domain K01972 - 6.5.1.2 1.794e-265 839.0
CMS3_k127_2808205_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 455.0
CMS3_k127_2808205_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001094 252.0
CMS3_k127_2808205_3 phosphoribosyltransferase K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000004483 249.0
CMS3_k127_2808205_4 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000006877 209.0
CMS3_k127_2808205_5 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000001979 105.0
CMS3_k127_2836020_0 P-type ATPase K17686 - 3.6.3.54 0.0 1108.0
CMS3_k127_2836020_1 Multicopper oxidase K22348 - 1.16.3.3 7.762e-264 819.0
CMS3_k127_2836020_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 482.0
CMS3_k127_2836020_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000498 187.0
CMS3_k127_2836020_4 - - - - 0.0000000000000000000001286 106.0
CMS3_k127_2836020_5 - - - - 0.0000000007614 65.0
CMS3_k127_2836020_6 - - - - 0.0004972 46.0
CMS3_k127_28919_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001717 302.0
CMS3_k127_28919_1 IPT/TIG domain - - - 0.000000000000000000000002647 119.0
CMS3_k127_2973439_0 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 569.0
CMS3_k127_2973439_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 416.0
CMS3_k127_2973439_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 342.0
CMS3_k127_2973439_3 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005467 264.0
CMS3_k127_2973439_4 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000004957 147.0
CMS3_k127_2973439_5 FR47-like protein - - - 0.00000000000000000000000000000000000002034 153.0
CMS3_k127_2973439_6 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000000172 110.0
CMS3_k127_2975696_0 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 616.0
CMS3_k127_2975696_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 559.0
CMS3_k127_2975696_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 526.0
CMS3_k127_2975696_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 447.0
CMS3_k127_2975696_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 347.0
CMS3_k127_2975696_5 HAD-hyrolase-like K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004665 276.0
CMS3_k127_2975696_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000004076 174.0
CMS3_k127_2975696_7 SmpA / OmlA family - - - 0.00000000000000000001041 95.0
CMS3_k127_2975696_8 transporter K07238 - - 0.00000000000003637 79.0
CMS3_k127_2979041_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 571.0
CMS3_k127_2979041_1 Benzoate membrane transport protein K05782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 554.0
CMS3_k127_2979041_2 Major Facilitator Superfamily - - - 0.0000000000000000000000001182 116.0
CMS3_k127_3005902_0 TRAP-type C4-dicarboxylate transport system small permease component K11689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 347.0
CMS3_k127_3005902_1 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 296.0
CMS3_k127_3005902_2 TRAP-type C4-dicarboxylate transport system, large permease K11690 - - 0.00000000000000000000000000000000000000001852 153.0
CMS3_k127_3015979_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 4.31e-284 876.0
CMS3_k127_3015979_1 Belongs to the GARS family K01945 - 6.3.4.13 5.713e-208 651.0
CMS3_k127_3015979_2 Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors K12973 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009279,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016409,GO:0016416,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044462,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.251 0.0000000000000000000000000000000000000000004731 170.0
CMS3_k127_3025331_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 616.0
CMS3_k127_3025331_1 Major facilitator superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 486.0
CMS3_k127_3025331_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 330.0
CMS3_k127_3025331_3 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001765 239.0
CMS3_k127_3025331_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000001053 234.0
CMS3_k127_3025331_5 YMGG-like Gly-zipper - - - 0.000000000000000000000000000000000000000000000000000000000000000003194 233.0
CMS3_k127_3025331_6 - - - - 0.000000000000000000000004803 113.0
CMS3_k127_3025331_7 - - - - 0.00000000000000000000009878 102.0
CMS3_k127_3025331_8 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000009636 63.0
CMS3_k127_3025331_9 Phage Tail Collar Domain - - - 0.0000001886 55.0
CMS3_k127_3095647_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 323.0
CMS3_k127_3095647_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 317.0
CMS3_k127_3095647_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001057 278.0
CMS3_k127_3095647_3 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000001697 234.0
CMS3_k127_3095647_4 Biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000000000000000000003068 198.0
CMS3_k127_3095647_5 Trm112p-like protein K09791 - - 0.00000000000001457 74.0
CMS3_k127_3118882_0 Cytochrome c554 and c-prime - - - 6.273e-264 827.0
CMS3_k127_3118882_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 452.0
CMS3_k127_3118882_2 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008983 407.0
CMS3_k127_3118882_3 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002689 271.0
CMS3_k127_3118882_4 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000000000000000000002408 226.0
CMS3_k127_3118882_5 Pfam:DUF1049 - - - 0.000000000003651 72.0
CMS3_k127_3250071_0 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 591.0
CMS3_k127_3250071_1 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 482.0
CMS3_k127_3250071_2 secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 407.0
CMS3_k127_3250071_3 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 369.0
CMS3_k127_3250071_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000001613 213.0
CMS3_k127_3250071_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000228 158.0
CMS3_k127_3276135_0 of ABC transporters with duplicated ATPase - - - 6.429e-292 914.0
CMS3_k127_3276135_1 Eco57I restriction-modification methylase K07317 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000259 267.0
CMS3_k127_3276135_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 0.0000000001443 63.0
CMS3_k127_3321738_0 Acyl-CoA synthetase (NDP forming) K09181 - - 0.0 1327.0
CMS3_k127_3321738_1 RNA binding K06959 - - 0.0 1033.0
CMS3_k127_3321738_2 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 402.0
CMS3_k127_3321738_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 323.0
CMS3_k127_3321738_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000004966 222.0
CMS3_k127_3321738_5 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000000000000000000000000000483 165.0
CMS3_k127_3321738_6 Haloacid dehalogenase-like hydrolase K07025,K20866 - 3.1.3.10 0.00000000000000000000000000000000007499 142.0
CMS3_k127_3321738_7 Belongs to the ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000000000004874 139.0
CMS3_k127_3321738_8 Electron transfer flavoprotein alpha subunit K03522 - - 0.00000000000003624 79.0
CMS3_k127_3321738_9 Sulfate permease family K03321 - - 0.000002119 53.0
CMS3_k127_3338898_0 nitrite reductase NAD(P)H K00362 - 1.7.1.15 6.817e-279 865.0
CMS3_k127_3338898_1 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 533.0
CMS3_k127_3338898_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 445.0
CMS3_k127_3338898_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 399.0
CMS3_k127_3338898_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000001464 212.0
CMS3_k127_3338898_5 Cyclophilin-like K09143 - - 0.0000000000000000000000001864 113.0
CMS3_k127_3338898_6 - - - - 0.00000000000000001248 83.0
CMS3_k127_3338898_7 - - - - 0.00002583 53.0
CMS3_k127_341912_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1023.0
CMS3_k127_341912_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 364.0
CMS3_k127_341912_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000002099 130.0
CMS3_k127_3495530_0 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 414.0
CMS3_k127_3495530_1 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 287.0
CMS3_k127_3495530_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000001017 239.0
CMS3_k127_3495530_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003945 235.0
CMS3_k127_359733_0 Belongs to the BCCT transporter (TC 2.A.15) family K02168,K03451 - - 0.0 1017.0
CMS3_k127_359733_1 Part of a membrane complex involved in electron transport K03615 - - 1.894e-216 683.0
CMS3_k127_359733_10 FIST_C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005534 271.0
CMS3_k127_359733_11 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000000000008183 250.0
CMS3_k127_359733_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000001992 219.0
CMS3_k127_359733_13 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000007236 209.0
CMS3_k127_359733_14 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000000000000000000000002566 188.0
CMS3_k127_359733_15 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000004874 116.0
CMS3_k127_359733_16 - - - - 0.0000000004993 71.0
CMS3_k127_359733_2 DNA replication, recombination, and repair K07478 - - 7.624e-203 640.0
CMS3_k127_359733_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 5.411e-200 633.0
CMS3_k127_359733_4 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 499.0
CMS3_k127_359733_5 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 425.0
CMS3_k127_359733_6 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 414.0
CMS3_k127_359733_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 400.0
CMS3_k127_359733_8 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 306.0
CMS3_k127_359733_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 291.0
CMS3_k127_3601357_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.901e-250 786.0
CMS3_k127_3601357_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 3.954e-220 703.0
CMS3_k127_3601357_2 cobalamin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 587.0
CMS3_k127_3601357_3 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000003162 192.0
CMS3_k127_3601357_4 glyoxalase K06996 - - 0.0000000000000000000000000000000000000000003028 174.0
CMS3_k127_3610474_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 4.363e-204 685.0
CMS3_k127_3610474_1 Surface antigen K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 463.0
CMS3_k127_3610474_2 beta-lactamase activity K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001745 256.0
CMS3_k127_3610474_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000007782 221.0
CMS3_k127_3621741_0 Domain of unknown function (DUF3492) - - - 1.486e-224 721.0
CMS3_k127_3621741_1 Putative exopolysaccharide Exporter (EPS-E) K21012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 601.0
CMS3_k127_3621741_2 PelD GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 403.0
CMS3_k127_3621741_3 Tetratricopeptide repeat K21010 - - 0.000000000000000000000000000000000000000000000000000000000000000000009797 247.0
CMS3_k127_3621741_4 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000001151 174.0
CMS3_k127_3621741_5 Tetratricopeptide repeat K21007 - - 0.000000000000000000002678 102.0
CMS3_k127_3627839_0 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 483.0
CMS3_k127_3627839_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 377.0
CMS3_k127_3627839_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000003705 88.0
CMS3_k127_3627839_3 - - - - 0.00000000000002356 79.0
CMS3_k127_3627839_4 conserved small protein - - - 0.00000008045 56.0
CMS3_k127_3650493_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1729.0
CMS3_k127_3650493_1 Circularly permuted ATP-grasp type 2 - - - 1.912e-309 968.0
CMS3_k127_3650493_10 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000004666 94.0
CMS3_k127_3650493_11 Positive regulator of sigma(E), RseC/MucC - - - 0.0000004238 58.0
CMS3_k127_3650493_12 methyl-accepting chemotaxis protein K03406 - - 0.0000005911 59.0
CMS3_k127_3650493_2 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 575.0
CMS3_k127_3650493_3 HMGL-like K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 471.0
CMS3_k127_3650493_4 Bacterial transglutaminase-like N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 315.0
CMS3_k127_3650493_5 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004118 271.0
CMS3_k127_3650493_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000159 247.0
CMS3_k127_3650493_7 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000003577 144.0
CMS3_k127_3650493_8 4Fe-4S binding domain - - - 0.000000000000000000000000004686 123.0
CMS3_k127_3650493_9 Radical SAM superfamily - - - 0.0000000000000000000000003577 107.0
CMS3_k127_3682829_0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 485.0
CMS3_k127_3682829_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 401.0
CMS3_k127_3682829_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 396.0
CMS3_k127_3682829_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001243 289.0
CMS3_k127_3682829_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000003583 63.0
CMS3_k127_370819_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.003e-276 859.0
CMS3_k127_370819_1 Thioesterase superfamily K07107 - - 0.0000000000000000000000000000000000000000000002095 171.0
CMS3_k127_370819_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000001519 162.0
CMS3_k127_370819_3 Methyl-accepting chemotaxis protein K03406 - - 0.000004044 51.0
CMS3_k127_3813011_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.886e-259 803.0
CMS3_k127_3813011_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 4.238e-220 690.0
CMS3_k127_3813011_10 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 321.0
CMS3_k127_3813011_11 SecretomeP prediction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 313.0
CMS3_k127_3813011_12 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 309.0
CMS3_k127_3813011_13 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 306.0
CMS3_k127_3813011_14 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000000000000000000000003266 216.0
CMS3_k127_3813011_15 Nucleotide transport and metabolism Carbohydrate transport and metabolism General function prediction only K02503 - - 0.00000000000000000000000000000000000000000000000008665 185.0
CMS3_k127_3813011_16 Amino acid transport and metabolism K01523 - 3.6.1.31 0.000000000000000000000000000000000000001453 156.0
CMS3_k127_3813011_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000002989 121.0
CMS3_k127_3813011_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000002736 109.0
CMS3_k127_3813011_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 5.295e-214 670.0
CMS3_k127_3813011_3 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 537.0
CMS3_k127_3813011_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 485.0
CMS3_k127_3813011_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 433.0
CMS3_k127_3813011_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 414.0
CMS3_k127_3813011_7 glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 398.0
CMS3_k127_3813011_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 382.0
CMS3_k127_3813011_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 357.0
CMS3_k127_3840570_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1345.0
CMS3_k127_3840570_1 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1115.0
CMS3_k127_3840570_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001183 258.0
CMS3_k127_3840570_11 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004429 243.0
CMS3_k127_3840570_12 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000002033 244.0
CMS3_k127_3840570_13 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000003416 244.0
CMS3_k127_3840570_14 FCD K05799,K14348 - - 0.0000000000000000000000000000000000000000000000000000000000000000161 233.0
CMS3_k127_3840570_15 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000001634 224.0
CMS3_k127_3840570_16 Oligoketide cyclase lipid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000001629 228.0
CMS3_k127_3840570_17 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000001354 177.0
CMS3_k127_3840570_18 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000000000000000000006665 143.0
CMS3_k127_3840570_19 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000002644 90.0
CMS3_k127_3840570_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.621e-257 799.0
CMS3_k127_3840570_20 Domain of unknown function (DUF4124) - - - 0.000000005486 64.0
CMS3_k127_3840570_3 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K03299 - - 2.304e-242 762.0
CMS3_k127_3840570_4 Iron-sulfur cluster binding protein K18929 - - 1.681e-225 710.0
CMS3_k127_3840570_5 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 574.0
CMS3_k127_3840570_6 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 438.0
CMS3_k127_3840570_7 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 394.0
CMS3_k127_3840570_8 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 386.0
CMS3_k127_3840570_9 Cysteine-rich domain protein K11473,K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 321.0
CMS3_k127_3841889_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0 1467.0
CMS3_k127_3841889_1 ABC transporter K15738 - - 1.872e-251 791.0
CMS3_k127_3841889_10 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000634 101.0
CMS3_k127_3841889_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 489.0
CMS3_k127_3841889_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 396.0
CMS3_k127_3841889_4 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 376.0
CMS3_k127_3841889_5 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 313.0
CMS3_k127_3841889_6 Methyltransferase K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000002429 259.0
CMS3_k127_3841889_7 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000006962 228.0
CMS3_k127_3841889_8 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000002196 207.0
CMS3_k127_3841889_9 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.0000000000000000000000000005109 117.0
CMS3_k127_3869040_0 TIGRFAM Formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 2.116e-241 751.0
CMS3_k127_3869040_1 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0071704 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 428.0
CMS3_k127_3869040_10 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001774 266.0
CMS3_k127_3869040_11 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002406 263.0
CMS3_k127_3869040_12 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.00000000000000000000000000000000000000000000000000000000001004 225.0
CMS3_k127_3869040_13 Histidine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000001103 227.0
CMS3_k127_3869040_14 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000004479 180.0
CMS3_k127_3869040_15 PFAM aspartate glutamate uridylate kinase - - - 0.00000000000000000000000000000000000000000516 174.0
CMS3_k127_3869040_16 - K06992 - - 0.000000000000000000000000000000000000001391 159.0
CMS3_k127_3869040_17 Domain of unknown function (DUF5062) - - - 0.000000000000000000000000000000000002044 140.0
CMS3_k127_3869040_2 6-pyruvoyl tetrahydropterin synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 417.0
CMS3_k127_3869040_20 GDSL-like Lipase/Acylhydrolase - - - 0.00004977 55.0
CMS3_k127_3869040_3 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 384.0
CMS3_k127_3869040_4 RimK-like ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 365.0
CMS3_k127_3869040_5 Methylene-tetrahydromethanopterin dehydrogenase K10714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 359.0
CMS3_k127_3869040_6 C1 transfer pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 323.0
CMS3_k127_3869040_7 PFAM GHMP kinases C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 319.0
CMS3_k127_3869040_8 PFAM Formaldehyde-activating enzyme K10713 - 4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 295.0
CMS3_k127_3869040_9 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002147 273.0
CMS3_k127_3893328_0 Cysteine-rich domain - - - 1.322e-234 732.0
CMS3_k127_3893328_1 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 604.0
CMS3_k127_3893328_10 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001467 241.0
CMS3_k127_3893328_11 ferredoxin-type protein napF K02572 - - 0.000000000000000000000000000000000000000000000001325 179.0
CMS3_k127_3893328_12 protein involved in formation of periplasmic nitrate reductase K02570 - - 0.0000000001482 70.0
CMS3_k127_3893328_2 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 451.0
CMS3_k127_3893328_3 Mo-molybdopterin cofactor biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 365.0
CMS3_k127_3893328_4 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 310.0
CMS3_k127_3893328_5 Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism K00372,K02567 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 299.0
CMS3_k127_3893328_6 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001068 265.0
CMS3_k127_3893328_7 Transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001608 273.0
CMS3_k127_3893328_8 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001406 271.0
CMS3_k127_3893328_9 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000002192 266.0
CMS3_k127_3895959_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 9.249e-289 902.0
CMS3_k127_3895959_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 3.158e-273 860.0
CMS3_k127_3895959_10 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.0000000000000000000000000000000004276 137.0
CMS3_k127_3895959_11 - - - - 0.00000000000000000001301 96.0
CMS3_k127_3895959_2 Acetyl-coenzyme A transporter 1 K08218 - - 1.161e-210 667.0
CMS3_k127_3895959_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 475.0
CMS3_k127_3895959_4 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 380.0
CMS3_k127_3895959_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 345.0
CMS3_k127_3895959_6 The short-chain dehydrogenases reductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 287.0
CMS3_k127_3895959_7 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 273.0
CMS3_k127_3895959_8 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000003681 194.0
CMS3_k127_3895959_9 cell division protein - - - 0.00000000000000000000000000000000000000000005776 167.0
CMS3_k127_3902471_0 serine protease K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 486.0
CMS3_k127_3902471_1 PFAM Glycosyl transferase, family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 426.0
CMS3_k127_3902471_10 pteridine-dependent deoxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 291.0
CMS3_k127_3902471_11 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000008261 260.0
CMS3_k127_3902471_12 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007789 268.0
CMS3_k127_3902471_13 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000001603 251.0
CMS3_k127_3902471_14 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000003982 186.0
CMS3_k127_3902471_15 dehydratase - - - 0.000000000000000000000000000000000000000001858 169.0
CMS3_k127_3902471_16 OmpA family K03286 - - 0.000000000000000000000000000000000000002507 153.0
CMS3_k127_3902471_17 Belongs to the ompA family K03286 - - 0.00000000002754 69.0
CMS3_k127_3902471_2 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 424.0
CMS3_k127_3902471_3 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 377.0
CMS3_k127_3902471_4 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 374.0
CMS3_k127_3902471_5 NAD dependent epimerase/dehydratase family K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 367.0
CMS3_k127_3902471_6 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 369.0
CMS3_k127_3902471_7 MltA-interacting protein MipA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 314.0
CMS3_k127_3902471_8 Beta-ketoacyl synthase, N-terminal domain K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 301.0
CMS3_k127_3902471_9 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 291.0
CMS3_k127_3922790_0 response regulator receiver K02658 - - 0.0000000000000000000000000000000000000000000000000000000000000001253 225.0
CMS3_k127_3922790_1 cheY-homologous receiver domain K02657 - - 0.000000000000000000000000000000000000000000000000000000000000001488 221.0
CMS3_k127_3922790_2 Chemotaxis signal transduction protein K02659 - - 0.000000000000000000000000000000000000000000000000000000004631 203.0
CMS3_k127_3922790_3 Methyl-accepting chemotaxis protein K02660 - - 0.0000000000000000000000000000000000000000000000000000008012 204.0
CMS3_k127_3922790_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000007171 129.0
CMS3_k127_3951494_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1064.0
CMS3_k127_3951494_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 574.0
CMS3_k127_3951494_2 Carboxysome Shell Carbonic Anhydrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 503.0
CMS3_k127_3951494_3 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000000003132 104.0
CMS3_k127_3951494_4 Mechanosensitive ion channel - - - 0.000000000004497 70.0
CMS3_k127_3951494_5 Gram-negative porin - - - 0.000001305 57.0
CMS3_k127_3955665_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1463.0
CMS3_k127_3955665_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 1.841e-216 684.0
CMS3_k127_3955665_2 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 484.0
CMS3_k127_3955665_3 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000205 241.0
CMS3_k127_3955665_4 Phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000005965 214.0
CMS3_k127_3955665_5 PKD domain - - - 0.00000000000000000000000000005422 134.0
CMS3_k127_3955665_6 Peptidase family M48 - - - 0.0000000000000003299 79.0
CMS3_k127_3970409_0 Poly-beta-hydroxybutyrate K03821 - - 5.599e-262 819.0
CMS3_k127_3970409_1 regulation of methylation-dependent chromatin silencing K03684,K09968 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002833 266.0
CMS3_k127_3970409_2 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000000009993 226.0
CMS3_k127_3970409_3 hydrogenase maturation protease - - - 0.0002999 44.0
CMS3_k127_4005022_0 Aldehyde dehydrogenase family - - - 1.573e-197 624.0
CMS3_k127_4005022_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000003238 226.0
CMS3_k127_4021056_0 serine threonine protein kinase - - - 2.724e-230 731.0
CMS3_k127_4021056_1 diguanylate cyclase - - - 3.54e-202 647.0
CMS3_k127_4021056_2 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 535.0
CMS3_k127_4021056_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 317.0
CMS3_k127_4021056_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 315.0
CMS3_k127_4021056_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002571 281.0
CMS3_k127_4021056_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000008624 245.0
CMS3_k127_4021056_7 Protein of unknown function (DUF3293) - - - 0.00003648 51.0
CMS3_k127_4045306_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1139.0
CMS3_k127_4045306_1 C-terminal, D2-small domain, of ClpB protein K03694 - - 0.0 1000.0
CMS3_k127_4045306_2 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 381.0
CMS3_k127_4045306_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000006313 218.0
CMS3_k127_4045306_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000001321 160.0
CMS3_k127_4045306_5 Cold shock K03704 - - 0.000000000000000000000000000000000006106 138.0
CMS3_k127_4045306_6 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000246 81.0
CMS3_k127_4052609_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 6.193e-250 777.0
CMS3_k127_4052609_1 homoserine dehydrogenase K00003 - 1.1.1.3 4.793e-229 720.0
CMS3_k127_4052609_10 NAD(P)H-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000000001045 215.0
CMS3_k127_4052609_11 - - - - 0.000000000000000000000000000000000000000000000000008179 191.0
CMS3_k127_4052609_12 Small multidrug resistance - - - 0.0000000000000000000000000000000000000000001131 166.0
CMS3_k127_4052609_13 PFAM CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000000000002295 162.0
CMS3_k127_4052609_14 MazG-like family - - - 0.00000000000000000000000000000000000000001972 155.0
CMS3_k127_4052609_15 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000001805 136.0
CMS3_k127_4052609_2 Aminotransferase K14260 - 2.6.1.2,2.6.1.66 1.884e-220 691.0
CMS3_k127_4052609_3 Lipoprotein-releasing system permease protein K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 477.0
CMS3_k127_4052609_4 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 380.0
CMS3_k127_4052609_5 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 356.0
CMS3_k127_4052609_6 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 336.0
CMS3_k127_4052609_7 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 289.0
CMS3_k127_4052609_8 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003658 271.0
CMS3_k127_4052609_9 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000003644 214.0
CMS3_k127_4076721_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1076.0
CMS3_k127_4076721_1 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 488.0
CMS3_k127_4076721_2 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 398.0
CMS3_k127_4076721_3 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 331.0
CMS3_k127_4076721_4 Fe-S oxidoreductase K21834 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001022 258.0
CMS3_k127_4076721_5 - - - - 0.000000000000000000001319 98.0
CMS3_k127_4119568_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1244.0
CMS3_k127_4119568_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1101.0
CMS3_k127_4119568_10 - - - - 0.000000000000000000008206 101.0
CMS3_k127_4119568_2 Elongator protein 3, MiaB family, Radical SAM - - - 5e-324 1004.0
CMS3_k127_4119568_3 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 2.014e-194 630.0
CMS3_k127_4119568_4 Glucokinase K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 295.0
CMS3_k127_4119568_5 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 289.0
CMS3_k127_4119568_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001258 280.0
CMS3_k127_4119568_7 PhnA Zinc-Ribbon K06193 - - 0.0000000000000000000000000000000000000000002035 164.0
CMS3_k127_4119568_9 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000001907 130.0
CMS3_k127_4124630_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 411.0
CMS3_k127_4124630_1 helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 404.0
CMS3_k127_4124630_2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000002536 246.0
CMS3_k127_4128195_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 572.0
CMS3_k127_4128195_1 signal transduction histidine kinase K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000001825 193.0
CMS3_k127_4128195_2 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 - 3.5.1.28 0.000000000000000000000009157 104.0
CMS3_k127_4151151_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 535.0
CMS3_k127_4151151_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 294.0
CMS3_k127_4151151_2 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000001176 228.0
CMS3_k127_4151151_3 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000001539 71.0
CMS3_k127_4166555_0 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 5.237e-252 782.0
CMS3_k127_4166555_1 type II secretion system protein K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 600.0
CMS3_k127_4166555_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02464,K02654 - 3.4.23.43 0.000000000000000000000000000000000000259 143.0
CMS3_k127_417893_0 Putative diguanylate phosphodiesterase - - - 4.754e-241 779.0
CMS3_k127_417893_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 512.0
CMS3_k127_417893_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 448.0
CMS3_k127_417893_3 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 407.0
CMS3_k127_417893_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 375.0
CMS3_k127_417893_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000009751 261.0
CMS3_k127_417893_6 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000001595 174.0
CMS3_k127_417893_7 Phage integrase family - - - 0.00002976 46.0
CMS3_k127_4196109_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.005e-255 795.0
CMS3_k127_4196109_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 599.0
CMS3_k127_4196109_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 535.0
CMS3_k127_4196109_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 466.0
CMS3_k127_4196109_4 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000008866 250.0
CMS3_k127_4196109_5 colicin V production K03558 - - 0.00000000000000000000000000000000000000000000001938 175.0
CMS3_k127_4196109_6 Sporulation related domain K03749 - - 0.0000000000000000000000000000000000008074 147.0
CMS3_k127_4196109_7 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000316 44.0
CMS3_k127_4210371_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.1e-283 879.0
CMS3_k127_4210371_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 8.099e-256 797.0
CMS3_k127_4210371_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.916e-232 724.0
CMS3_k127_4210371_3 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004721 277.0
CMS3_k127_4221587_0 Dynamin family - - - 8e-268 839.0
CMS3_k127_4221587_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 430.0
CMS3_k127_4221587_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 361.0
CMS3_k127_4221587_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000002917 246.0
CMS3_k127_4221587_4 methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000002598 220.0
CMS3_k127_4221587_5 - - - - 0.0000000000000000000000000000000000000000000000000000000001066 211.0
CMS3_k127_4221587_6 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000001161 162.0
CMS3_k127_4221587_7 Peptidase M16 K07263 - - 0.00000000000000000000000000002696 118.0
CMS3_k127_4224729_0 LVIVD repeat - - - 0.0 1743.0
CMS3_k127_4224729_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 6.385e-202 653.0
CMS3_k127_4224729_2 - - - - 1.067e-201 658.0
CMS3_k127_4224729_3 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 359.0
CMS3_k127_4224729_4 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004888 261.0
CMS3_k127_4230696_0 flagellar motor switch protein K02410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 558.0
CMS3_k127_4230696_1 ATPase FliI YscN family K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002531 282.0
CMS3_k127_4230696_2 Flagellar assembly protein FliH K02411 - - 0.00000000000000000000000000000000000000000000004219 178.0
CMS3_k127_4230696_3 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000001337 163.0
CMS3_k127_4277791_0 PBP superfamily domain K02040 - - 0.00000000000000000000000000000002347 138.0
CMS3_k127_4277791_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000001043 84.0
CMS3_k127_4315807_0 NMT1-like family K22067 - - 1.85e-213 674.0
CMS3_k127_4315807_1 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) K05951 - 2.4.2.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 387.0
CMS3_k127_4315807_2 PFAM binding-protein-dependent transport systems inner membrane component K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 331.0
CMS3_k127_4315807_3 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000002634 277.0
CMS3_k127_4315807_4 ANTAR K07183 - - 0.00000000000000000000000000000000000000000000000000000000000000000855 232.0
CMS3_k127_4315807_5 Putative regulatory protein - - - 0.000000000000000001136 88.0
CMS3_k127_4315807_6 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K15577 - - 0.00000000904 56.0
CMS3_k127_4361762_0 STAS domain K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 614.0
CMS3_k127_4361762_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 512.0
CMS3_k127_4361762_10 - - - - 0.00000000000000000000002273 106.0
CMS3_k127_4361762_2 HI0933-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 315.0
CMS3_k127_4361762_3 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 301.0
CMS3_k127_4361762_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000031 260.0
CMS3_k127_4361762_5 COG0471 Di- and tricarboxylate transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000003664 240.0
CMS3_k127_4361762_6 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000001102 235.0
CMS3_k127_4361762_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000005723 214.0
CMS3_k127_4361762_8 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000002706 215.0
CMS3_k127_4361762_9 Peptidase S24-like - - - 0.0000000000000000000000000002106 119.0
CMS3_k127_4364279_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.273e-286 882.0
CMS3_k127_4364279_1 Elongator protein 3, MiaB family, Radical SAM - - - 2.214e-230 722.0
CMS3_k127_4364279_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 549.0
CMS3_k127_4364279_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 473.0
CMS3_k127_4364279_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000002405 233.0
CMS3_k127_4364279_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000000000000003654 217.0
CMS3_k127_4364279_6 protein conserved in bacteria K03690 - - 0.00005192 53.0
CMS3_k127_4383816_0 Methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 455.0
CMS3_k127_4383816_1 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006796 269.0
CMS3_k127_4383816_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000501 124.0
CMS3_k127_4402338_0 SNARE associated Golgi protein - - - 0.0 1133.0
CMS3_k127_4402338_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.263e-232 742.0
CMS3_k127_4402338_10 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001113 274.0
CMS3_k127_4402338_11 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000274 229.0
CMS3_k127_4402338_12 NfeD-like C-terminal, partner-binding K07340 - - 0.00000000000000000000000000000000000000000001838 168.0
CMS3_k127_4402338_13 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000005666 173.0
CMS3_k127_4402338_14 PFAM BFD domain protein 2Fe-2S -binding domain protein K02192 - - 0.0000000000006261 70.0
CMS3_k127_4402338_15 - - - - 0.000000006388 61.0
CMS3_k127_4402338_16 Hemin uptake protein - - - 0.00004517 49.0
CMS3_k127_4402338_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 606.0
CMS3_k127_4402338_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 481.0
CMS3_k127_4402338_4 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 423.0
CMS3_k127_4402338_5 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 358.0
CMS3_k127_4402338_6 Bacterial protein of unknown function (DUF898) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 324.0
CMS3_k127_4402338_7 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 301.0
CMS3_k127_4402338_8 Uncharacterized protein conserved in bacteria (DUF2325) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000599 278.0
CMS3_k127_4402338_9 iron-storage protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001599 260.0
CMS3_k127_4412454_0 CoA binding domain - - - 0.0 1072.0
CMS3_k127_4412454_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 425.0
CMS3_k127_4412454_10 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000003022 174.0
CMS3_k127_4412454_11 Chemoreceptor zinc-binding domain - - - 0.000000000000000000000000000000854 125.0
CMS3_k127_4412454_12 - - - - 0.000000000000000000000000006474 121.0
CMS3_k127_4412454_13 Cytochrome c K08738 - - 0.000000000000000000000000007155 119.0
CMS3_k127_4412454_14 - - - - 0.000000000000000003536 90.0
CMS3_k127_4412454_15 Tfp pilus assembly protein FimV - - - 0.000001155 57.0
CMS3_k127_4412454_2 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 425.0
CMS3_k127_4412454_3 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 306.0
CMS3_k127_4412454_4 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000008401 259.0
CMS3_k127_4412454_5 Conserved hypothetical ATP binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000000000000009847 220.0
CMS3_k127_4412454_6 HD domain - - - 0.000000000000000000000000000000000000000000000000000000006768 212.0
CMS3_k127_4412454_7 Elements of external origin K07497 - - 0.0000000000000000000000000000000000000000000000000003374 186.0
CMS3_k127_4412454_8 - - - - 0.00000000000000000000000000000000000000000000000006364 192.0
CMS3_k127_4412454_9 Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000000000000000000000000002732 178.0
CMS3_k127_4417973_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 9.109e-291 910.0
CMS3_k127_4417973_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.338e-213 677.0
CMS3_k127_4417973_2 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 570.0
CMS3_k127_4417973_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 415.0
CMS3_k127_4417973_4 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002405 273.0
CMS3_k127_4417973_5 PFAM peptidase M17 leucyl aminopeptidase domain protein K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000004437 194.0
CMS3_k127_4417973_6 Yqey-like protein - - - 0.0000000000000000000000000000000000000000000000000004757 188.0
CMS3_k127_4417973_7 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000000000000006611 164.0
CMS3_k127_4417973_8 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000000005592 128.0
CMS3_k127_4442737_0 lysine 2,3-aminomutase K01843 - 5.4.3.2 1.468e-218 686.0
CMS3_k127_4442737_1 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 549.0
CMS3_k127_4442737_2 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000181 266.0
CMS3_k127_4442737_3 Isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000003357 224.0
CMS3_k127_4442737_4 DSBA Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000002691 221.0
CMS3_k127_4442737_5 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000001209 211.0
CMS3_k127_4442737_6 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.0000000000000000000000001891 109.0
CMS3_k127_4442737_7 FKBP-type peptidyl-prolyl cis-trans isomerase K03772 - 5.2.1.8 0.000000000000000000002206 93.0
CMS3_k127_4442737_8 Chemoreceptor zinc-binding domain - - - 0.0000000007955 69.0
CMS3_k127_4447089_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 5.097e-268 833.0
CMS3_k127_4447089_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 7.027e-254 790.0
CMS3_k127_4447089_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 316.0
CMS3_k127_4447089_11 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 302.0
CMS3_k127_4447089_12 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000001958 250.0
CMS3_k127_4447089_13 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000473 209.0
CMS3_k127_4447089_14 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000001465 207.0
CMS3_k127_4447089_15 transmembrane transporter activity K16783,K16785,K16786,K16787 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000001188 70.0
CMS3_k127_4447089_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.184e-227 709.0
CMS3_k127_4447089_3 COG3170 Tfp pilus assembly protein FimV K08086 - - 3.654e-205 668.0
CMS3_k127_4447089_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.46e-197 619.0
CMS3_k127_4447089_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 593.0
CMS3_k127_4447089_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 587.0
CMS3_k127_4447089_7 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 508.0
CMS3_k127_4447089_8 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 374.0
CMS3_k127_4447089_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 351.0
CMS3_k127_4453883_0 extracellular solute-binding protein - - - 0.0 1032.0
CMS3_k127_4453883_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 2.542e-246 793.0
CMS3_k127_4453883_10 - - - - 0.000000008316 59.0
CMS3_k127_4453883_11 - - - - 0.00000009331 63.0
CMS3_k127_4453883_2 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 584.0
CMS3_k127_4453883_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 544.0
CMS3_k127_4453883_4 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 535.0
CMS3_k127_4453883_5 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 443.0
CMS3_k127_4453883_6 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 412.0
CMS3_k127_4453883_7 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 400.0
CMS3_k127_4453883_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000001575 198.0
CMS3_k127_4489758_0 Threonine synthase K01733 - 4.2.3.1 8.58e-237 739.0
CMS3_k127_4489758_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002465 244.0
CMS3_k127_4489758_2 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000002269 236.0
CMS3_k127_4489758_3 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000005535 213.0
CMS3_k127_4489758_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000001247 135.0
CMS3_k127_4489758_5 - - - - 0.000000000000000002773 85.0
CMS3_k127_4516609_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 1.499e-233 729.0
CMS3_k127_4516609_1 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 480.0
CMS3_k127_4516609_2 membrane - - - 0.00000000000000000000005598 109.0
CMS3_k127_4548230_0 alginate biosynthesis protein AlgZ FimS K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006026 284.0
CMS3_k127_4548230_1 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002529 278.0
CMS3_k127_4623818_0 Belongs to the flagella basal body rod proteins family K02396 - - 3.502e-218 698.0
CMS3_k127_4623818_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 492.0
CMS3_k127_4623818_2 Belongs to the flagella basal body rod proteins family K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 417.0
CMS3_k127_4623818_3 Bacterial flagellin C-terminal helical region K02397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 333.0
CMS3_k127_4623818_4 Flagellar rod assembly protein muramidase FlgJ K02395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 303.0
CMS3_k127_4623818_5 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000375 253.0
CMS3_k127_4623818_6 basal body rod protein K02391 - - 0.00000000000000000000000000000000000000000000003296 172.0
CMS3_k127_4637609_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1051.0
CMS3_k127_4637609_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.276e-309 953.0
CMS3_k127_4637609_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.827e-243 758.0
CMS3_k127_4637609_3 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 460.0
CMS3_k127_4637609_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
CMS3_k127_4637609_5 FKBP-type peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000002128 247.0
CMS3_k127_4637609_6 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000003126 213.0
CMS3_k127_4637609_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000004251 122.0
CMS3_k127_4637609_8 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000009484 114.0
CMS3_k127_4672200_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 562.0
CMS3_k127_4672200_1 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 535.0
CMS3_k127_4672200_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000000003519 173.0
CMS3_k127_4710816_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 2.179e-296 921.0
CMS3_k127_4710816_1 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 520.0
CMS3_k127_4710816_2 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001405 259.0
CMS3_k127_4710816_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000005003 244.0
CMS3_k127_4710816_4 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008637 243.0
CMS3_k127_4710816_5 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000000000000000000000009635 168.0
CMS3_k127_4714442_0 CHASE2 K01768 - 4.6.1.1 1.169e-228 723.0
CMS3_k127_4714442_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003384 284.0
CMS3_k127_4714442_2 Ndr family K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000003984 206.0
CMS3_k127_4714442_3 Bacterial SH3 domain - - - 0.0000000000000000000000000008026 119.0
CMS3_k127_4714442_4 oxygen carrier activity K07216 - - 0.0000000000000000000000001882 121.0
CMS3_k127_4730587_0 chorismate binding enzyme K01665,K03342 - 2.6.1.85,4.1.3.38 3.537e-223 717.0
CMS3_k127_4730587_1 Sigma-54 interaction domain - - - 1.228e-218 696.0
CMS3_k127_4730587_10 Putative heavy-metal chelation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 336.0
CMS3_k127_4730587_11 PFAM Flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000434 238.0
CMS3_k127_4730587_12 Protein of unknown function (DUF447) K09154 - - 0.00000000000000000000000000000000000000000000000000000000000004884 237.0
CMS3_k127_4730587_13 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000006427 210.0
CMS3_k127_4730587_14 4-HFC-P synthase - - - 0.00000000000000000000000000000000000000000000000002081 196.0
CMS3_k127_4730587_15 6-pyruvoyl tetrahydropterin synthase - - - 0.00000000000000000000000000000000000000000000000004353 190.0
CMS3_k127_4730587_16 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000425 187.0
CMS3_k127_4730587_17 peptidase - - - 0.0000000000000000000000000000007431 131.0
CMS3_k127_4730587_19 Protein of unknown function (DUF3567) - - - 0.000000000002702 75.0
CMS3_k127_4730587_2 dihydropteroate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 619.0
CMS3_k127_4730587_20 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0002187 46.0
CMS3_k127_4730587_3 AAA domain (dynein-related subfamily) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 545.0
CMS3_k127_4730587_4 protein containing a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 537.0
CMS3_k127_4730587_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 393.0
CMS3_k127_4730587_6 2-Keto-4-pentenoate hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 385.0
CMS3_k127_4730587_7 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 368.0
CMS3_k127_4730587_8 Formaldehyde-activating enzyme (Fae) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 329.0
CMS3_k127_4730587_9 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 329.0
CMS3_k127_473692_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 377.0
CMS3_k127_473692_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 317.0
CMS3_k127_473692_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005637 273.0
CMS3_k127_473692_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003918 263.0
CMS3_k127_473692_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000000001758 201.0
CMS3_k127_473692_5 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000000000000000000000000000000001164 169.0
CMS3_k127_473692_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000005039 77.0
CMS3_k127_4749805_0 efflux pump K19594 - - 0.0 1306.0
CMS3_k127_4749805_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 492.0
CMS3_k127_4749805_10 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000009427 129.0
CMS3_k127_4749805_11 Peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000000001878 118.0
CMS3_k127_4749805_12 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000003075 87.0
CMS3_k127_4749805_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 484.0
CMS3_k127_4749805_3 enzyme of heme biosynthesis K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 385.0
CMS3_k127_4749805_4 HemX, putative uroporphyrinogen-III C-methyltransferase K02496 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001425 280.0
CMS3_k127_4749805_5 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005332 239.0
CMS3_k127_4749805_6 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000002145 245.0
CMS3_k127_4749805_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298,K19586 - - 0.000000000000000000000000000000000000000000000000000000000000000000496 243.0
CMS3_k127_4749805_8 Efflux transporter outer membrane factor lipoprotein K18308 - - 0.000000000000000000000000000000000000000000000000004527 201.0
CMS3_k127_4749805_9 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000003983 179.0
CMS3_k127_4763421_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 7.671e-285 889.0
CMS3_k127_4763421_1 - - - - 3.299e-228 728.0
CMS3_k127_4763421_2 COG0436 Aspartate tyrosine aromatic aminotransferase K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 332.0
CMS3_k127_4771098_0 Signal transduction histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000005274 275.0
CMS3_k127_4771098_1 PucR C-terminal helix-turn-helix domain K15012 - - 0.0000000000000000000000000000000000000000000000196 190.0
CMS3_k127_4771098_2 Type II secretory pathway pseudopilin - - - 0.0000000000000000000000000000000000005443 150.0
CMS3_k127_4771098_3 type II secretion system protein G K02456 - - 0.00000000000000000000000000000003456 127.0
CMS3_k127_4779556_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1376.0
CMS3_k127_4779556_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 587.0
CMS3_k127_4779556_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 484.0
CMS3_k127_4779556_3 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 493.0
CMS3_k127_4779556_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 295.0
CMS3_k127_4779556_5 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001447 283.0
CMS3_k127_4779556_6 Protein of unknown function (DUF721) - - - 0.0000000000000000000000001198 111.0
CMS3_k127_4788719_0 Reductase C-terminal K00529,K16968 - 1.14.13.111,1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 447.0
CMS3_k127_4788719_1 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 371.0
CMS3_k127_4788719_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002481 277.0
CMS3_k127_4788719_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000003051 145.0
CMS3_k127_4803629_0 TRAP-type C4-dicarboxylate transport system, large permease K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 411.0
CMS3_k127_4803629_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 361.0
CMS3_k127_4803629_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000006336 244.0
CMS3_k127_4819964_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1543.0
CMS3_k127_4819964_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000002294 58.0
CMS3_k127_4829120_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1064.0
CMS3_k127_4829120_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 572.0
CMS3_k127_4829120_2 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 469.0
CMS3_k127_4829120_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 463.0
CMS3_k127_4829120_4 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 334.0
CMS3_k127_4829120_5 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000001688 225.0
CMS3_k127_4829120_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000002065 223.0
CMS3_k127_4829120_7 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000002654 177.0
CMS3_k127_4829120_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000009045 164.0
CMS3_k127_4835511_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 599.0
CMS3_k127_4835511_1 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 598.0
CMS3_k127_4835511_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 345.0
CMS3_k127_4835511_3 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000001141 192.0
CMS3_k127_4835511_4 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000008723 159.0
CMS3_k127_4835511_5 DSBA-like thioredoxin domain K14584 - 5.99.1.4 0.000000000000000000000000107 113.0
CMS3_k127_4852596_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 621.0
CMS3_k127_4852596_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000001227 104.0
CMS3_k127_4852596_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00009277 45.0
CMS3_k127_4858513_0 Sigma-54 interaction domain - - - 1.21e-240 752.0
CMS3_k127_4858513_1 Oxidative deamination of D-amino acids K00285 - 1.4.5.1 8.065e-235 732.0
CMS3_k127_4858513_2 PFAM Ethanolamine ammonia lyase large subunit K03735 - 4.3.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 323.0
CMS3_k127_4858513_3 Ethanolamine ammonia-lyase light chain (EutC) K03736 - 4.3.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000005521 272.0
CMS3_k127_4858513_4 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000003743 158.0
CMS3_k127_4858513_5 - - - - 0.000000000000000000000005426 106.0
CMS3_k127_4858513_6 Family of unknown function (DUF5329) - - - 0.0000002088 55.0
CMS3_k127_4872315_0 Oligopeptidase K01414 - 3.4.24.70 1.742e-315 980.0
CMS3_k127_4872315_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.289e-240 766.0
CMS3_k127_4872315_10 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 475.0
CMS3_k127_4872315_11 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 459.0
CMS3_k127_4872315_12 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 444.0
CMS3_k127_4872315_13 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 424.0
CMS3_k127_4872315_14 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 426.0
CMS3_k127_4872315_15 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 378.0
CMS3_k127_4872315_16 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 321.0
CMS3_k127_4872315_17 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 300.0
CMS3_k127_4872315_18 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001546 283.0
CMS3_k127_4872315_19 Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
CMS3_k127_4872315_2 Aldolase K01624 - 4.1.2.13 1.759e-207 652.0
CMS3_k127_4872315_20 FAD binding domain K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005298 276.0
CMS3_k127_4872315_21 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000000000009644 149.0
CMS3_k127_4872315_22 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000000007313 123.0
CMS3_k127_4872315_23 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000005719 111.0
CMS3_k127_4872315_24 Bacterial regulatory protein, Fis family K03557 - - 0.000000000000000000000001396 113.0
CMS3_k127_4872315_25 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000001323 86.0
CMS3_k127_4872315_26 SlyX K03745 - - 0.00000000000002347 80.0
CMS3_k127_4872315_3 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 5.889e-197 639.0
CMS3_k127_4872315_4 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 591.0
CMS3_k127_4872315_5 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 541.0
CMS3_k127_4872315_6 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 530.0
CMS3_k127_4872315_7 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 525.0
CMS3_k127_4872315_8 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 524.0
CMS3_k127_4872315_9 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 516.0
CMS3_k127_4879061_0 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000001186 243.0
CMS3_k127_4879061_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000002431 215.0
CMS3_k127_4879061_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000006662 140.0
CMS3_k127_4914879_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 413.0
CMS3_k127_4914879_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 382.0
CMS3_k127_4914879_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 316.0
CMS3_k127_4914879_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004981 267.0
CMS3_k127_4914879_4 Belongs to the skp family K06142 - - 0.00000000000000000000000000000000000000009824 160.0
CMS3_k127_4914879_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000003934 102.0
CMS3_k127_4922550_0 Chemotaxis signal transduction protein K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 523.0
CMS3_k127_4922550_1 Chemotaxis signal transduction protein K03415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 500.0
CMS3_k127_4922550_10 LysR substrate binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 303.0
CMS3_k127_4922550_11 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 297.0
CMS3_k127_4922550_12 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 306.0
CMS3_k127_4922550_13 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005137 259.0
CMS3_k127_4922550_14 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005298 261.0
CMS3_k127_4922550_15 Flavodoxin domain K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003719 254.0
CMS3_k127_4922550_16 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006384 250.0
CMS3_k127_4922550_17 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000002049 252.0
CMS3_k127_4922550_18 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000886 227.0
CMS3_k127_4922550_19 Response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000002471 222.0
CMS3_k127_4922550_2 Belongs to the DEAD box helicase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 511.0
CMS3_k127_4922550_20 COG0643 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000003315 216.0
CMS3_k127_4922550_21 Cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000013 198.0
CMS3_k127_4922550_22 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000001393 197.0
CMS3_k127_4922550_23 SMART zinc finger, CDGSH-type domain protein - - - 0.00000000000000000000000000003972 130.0
CMS3_k127_4922550_24 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0003862 51.0
CMS3_k127_4922550_3 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 421.0
CMS3_k127_4922550_4 flagellar motor protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 405.0
CMS3_k127_4922550_5 Alpha/beta hydrolase of unknown function (DUF915) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 402.0
CMS3_k127_4922550_6 Beta-lactamase K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 381.0
CMS3_k127_4922550_7 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 366.0
CMS3_k127_4922550_8 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 320.0
CMS3_k127_4922550_9 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 301.0
CMS3_k127_4924473_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.378e-249 774.0
CMS3_k127_4924473_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 409.0
CMS3_k127_4924473_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 372.0
CMS3_k127_4949883_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 507.0
CMS3_k127_4949883_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 425.0
CMS3_k127_4949883_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 303.0
CMS3_k127_4949883_3 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000001651 79.0
CMS3_k127_4960686_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.699e-225 707.0
CMS3_k127_4960686_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 443.0
CMS3_k127_4960686_2 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 306.0
CMS3_k127_4960686_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000004583 247.0
CMS3_k127_4960686_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0002223 43.0
CMS3_k127_4986108_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 1.705e-256 797.0
CMS3_k127_4986108_1 NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 340.0
CMS3_k127_4986108_2 4Fe-4S single cluster domain K18006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000583 250.0
CMS3_k127_5065431_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 483.0
CMS3_k127_5065431_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 375.0
CMS3_k127_5065431_2 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006817 268.0
CMS3_k127_5065431_3 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000004175 240.0
CMS3_k127_5065431_4 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000005451 115.0
CMS3_k127_5072316_0 Response regulator receiver modulated diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 578.0
CMS3_k127_5072316_1 Protein involved in transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 533.0
CMS3_k127_5072316_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000003954 119.0
CMS3_k127_5072316_11 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000002492 73.0
CMS3_k127_5072316_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007048 272.0
CMS3_k127_5072316_3 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009327 266.0
CMS3_k127_5072316_4 DNA replication, recombination, and repair K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000095 267.0
CMS3_k127_5072316_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000001487 219.0
CMS3_k127_5072316_6 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000002872 218.0
CMS3_k127_5072316_7 PFAM AMMECR1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000005875 215.0
CMS3_k127_5072316_8 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.0000000000000000000000000000000000000000000000005932 179.0
CMS3_k127_5072316_9 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000000000004135 172.0
CMS3_k127_5073670_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 573.0
CMS3_k127_5073670_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 490.0
CMS3_k127_5073670_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000001468 117.0
CMS3_k127_5073670_11 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000006925 66.0
CMS3_k127_5073670_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 471.0
CMS3_k127_5073670_3 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 449.0
CMS3_k127_5073670_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 410.0
CMS3_k127_5073670_5 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 308.0
CMS3_k127_5073670_6 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000024 260.0
CMS3_k127_5073670_7 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000001875 224.0
CMS3_k127_5073670_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000001025 222.0
CMS3_k127_5073670_9 SprA-related family - - - 0.00000000000000000000000000000007862 131.0
CMS3_k127_5095059_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.551e-197 626.0
CMS3_k127_5095059_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 580.0
CMS3_k127_5095059_10 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000003535 182.0
CMS3_k127_5095059_11 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.00000000000000000000000000000000000000000000008442 171.0
CMS3_k127_5095059_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000003117 179.0
CMS3_k127_5095059_13 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000002475 149.0
CMS3_k127_5095059_14 Modulates RecA activity K03565 - - 0.00000000000000000000000000002775 123.0
CMS3_k127_5095059_15 psiF repeat - - - 0.00000000000001166 78.0
CMS3_k127_5095059_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 478.0
CMS3_k127_5095059_3 Lipopolysaccharide export system ATP-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 395.0
CMS3_k127_5095059_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 389.0
CMS3_k127_5095059_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000008816 231.0
CMS3_k127_5095059_6 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000225 224.0
CMS3_k127_5095059_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000000000001076 212.0
CMS3_k127_5095059_8 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.000000000000000000000000000000000000000000000000000000000381 209.0
CMS3_k127_5095059_9 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000002026 194.0
CMS3_k127_5147992_0 PQQ enzyme repeat - - - 0.0 1147.0
CMS3_k127_5147992_1 SMART extracellular solute-binding protein, family 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 383.0
CMS3_k127_5147992_10 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000003713 122.0
CMS3_k127_5147992_11 - - - - 0.000000000000000000001014 100.0
CMS3_k127_5147992_12 Metallo-beta-lactamase superfamily - - - 0.00001247 53.0
CMS3_k127_5147992_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 340.0
CMS3_k127_5147992_3 Sulphur oxidation protein SoxZ K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 310.0
CMS3_k127_5147992_4 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000002076 222.0
CMS3_k127_5147992_5 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000005517 241.0
CMS3_k127_5147992_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000001132 209.0
CMS3_k127_5147992_7 - - - - 0.0000000000000000000000000000000000000000000000000000009977 200.0
CMS3_k127_5147992_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000008376 168.0
CMS3_k127_5147992_9 Protein of unknown function (DUF2380) - - - 0.0000000000000000000000000000000001271 139.0
CMS3_k127_5192168_0 Member of a two-component regulatory system K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 322.0
CMS3_k127_5192168_1 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000393 248.0
CMS3_k127_5192168_2 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000009806 185.0
CMS3_k127_5192168_3 maltose operon periplasmic K05775 - - 0.0000000001281 73.0
CMS3_k127_5201012_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 566.0
CMS3_k127_5201012_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 482.0
CMS3_k127_5201012_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 404.0
CMS3_k127_5201012_3 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000000000000000000000002329 191.0
CMS3_k127_5205052_0 FAD linked oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 463.0
CMS3_k127_5205052_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 375.0
CMS3_k127_5205052_2 membrane - - - 0.00000000000000000000000000000000000000000001322 166.0
CMS3_k127_5205052_3 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.000000000000000000002604 98.0
CMS3_k127_5205052_4 FAD binding domain protein - - - 0.0001924 49.0
CMS3_k127_5214541_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0 1007.0
CMS3_k127_5214541_1 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1002.0
CMS3_k127_5214541_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 445.0
CMS3_k127_5214541_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002192 273.0
CMS3_k127_5214541_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000007941 196.0
CMS3_k127_5214541_5 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000000003535 190.0
CMS3_k127_5214541_6 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.000000000000000000000000000000000000000000000000001388 188.0
CMS3_k127_5214541_7 HupF/HypC family K04653 - - 0.00000000000000000000000001143 116.0
CMS3_k127_5218486_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1339.0
CMS3_k127_522128_0 His Kinase A (phosphoacceptor) domain - - - 4.131e-256 815.0
CMS3_k127_522128_1 Ubiquinone biosynthesis hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 387.0
CMS3_k127_522128_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004222 262.0
CMS3_k127_522128_3 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000003723 186.0
CMS3_k127_5229612_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1036.0
CMS3_k127_5229612_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.68e-258 805.0
CMS3_k127_5229612_10 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 294.0
CMS3_k127_5229612_11 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001408 276.0
CMS3_k127_5229612_12 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000004541 264.0
CMS3_k127_5229612_13 Uroporphyrin-III C tetrapyrrole K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000001103 246.0
CMS3_k127_5229612_14 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000001126 229.0
CMS3_k127_5229612_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000004182 140.0
CMS3_k127_5229612_16 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000002701 131.0
CMS3_k127_5229612_17 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.000000000000000000000000000000005507 134.0
CMS3_k127_5229612_18 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000000007518 121.0
CMS3_k127_5229612_19 COG0526 Thiol-disulfide isomerase and thioredoxins K00384 - 1.8.1.9 0.00000000000000000000000007797 108.0
CMS3_k127_5229612_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 4.785e-213 666.0
CMS3_k127_5229612_20 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.0000000001874 69.0
CMS3_k127_5229612_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 1.196e-207 659.0
CMS3_k127_5229612_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 481.0
CMS3_k127_5229612_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 469.0
CMS3_k127_5229612_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 461.0
CMS3_k127_5229612_7 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 384.0
CMS3_k127_5229612_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 366.0
CMS3_k127_5229612_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 339.0
CMS3_k127_5234557_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1032.0
CMS3_k127_5234557_1 Molybdopterin biosynthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 502.0
CMS3_k127_5234557_2 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 315.0
CMS3_k127_5234557_3 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 289.0
CMS3_k127_5244382_0 Dinitrogenase iron-molybdenum cofactor K02585 - - 3.596e-256 803.0
CMS3_k127_5244382_1 SIR2-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 293.0
CMS3_k127_5244382_2 hemerythrin-like metal-binding K07216 - - 0.00000000000000000000000000000000000000146 152.0
CMS3_k127_5244382_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000001386 140.0
CMS3_k127_5244382_4 NifZ domain K02597 - - 0.000000000000000000000000000000002163 138.0
CMS3_k127_5244382_5 Iron-sulphur cluster biosynthesis - - - 0.000000000000000000000000000001079 126.0
CMS3_k127_5244382_6 nitrogen fixation K02593 - - 0.000000000000000000000002974 104.0
CMS3_k127_5244382_7 PFAM bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000465 108.0
CMS3_k127_5244382_8 - - - - 0.0000000000000000000000421 107.0
CMS3_k127_5244382_9 3-demethylubiquinone-9 3-methyltransferase - - - 0.00005384 51.0
CMS3_k127_5248182_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1823.0
CMS3_k127_5248182_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 559.0
CMS3_k127_5248182_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007429 256.0
CMS3_k127_5248182_11 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000001784 222.0
CMS3_k127_5248182_12 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000002653 222.0
CMS3_k127_5248182_13 Thioesterase domain K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000003628 213.0
CMS3_k127_5248182_14 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000285 200.0
CMS3_k127_5248182_15 PFAM YCII-related K09780 - - 0.00000000000000000000000000000000000000001087 155.0
CMS3_k127_5248182_16 diguanylate cyclase - - - 0.000000000000000000000000000000000000004479 160.0
CMS3_k127_5248182_17 Helix-turn-helix domain protein - - - 0.000000000000000000000000000002294 125.0
CMS3_k127_5248182_18 Domain of unknown function (DUF1857) - - - 0.000000000000000000000000001586 117.0
CMS3_k127_5248182_19 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000002017 106.0
CMS3_k127_5248182_2 Protein of unknown function (DUF2863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 463.0
CMS3_k127_5248182_20 nucleic acid-binding protein, contains PIN domain - - - 0.0000000000000000000005019 104.0
CMS3_k127_5248182_21 Protein of unknown function (DUF1161) - - - 0.000000000000000002443 87.0
CMS3_k127_5248182_22 - - - - 0.000000000001962 70.0
CMS3_k127_5248182_24 Transcriptional regulator - - - 0.0000009973 51.0
CMS3_k127_5248182_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 462.0
CMS3_k127_5248182_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 432.0
CMS3_k127_5248182_5 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 360.0
CMS3_k127_5248182_6 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 350.0
CMS3_k127_5248182_7 COG0210 Superfamily I DNA and RNA helicases K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 287.0
CMS3_k127_5248182_8 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009124 273.0
CMS3_k127_5248182_9 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000002246 271.0
CMS3_k127_5263487_0 Ammonium Transporter K03320 - - 4.159e-218 684.0
CMS3_k127_5263487_1 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000000004148 209.0
CMS3_k127_5263487_2 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000003432 164.0
CMS3_k127_5263487_3 Receptor family ligand binding region K01999 - - 0.0000000000000000006842 92.0
CMS3_k127_53378_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1238.0
CMS3_k127_53378_1 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 1.991e-205 648.0
CMS3_k127_53378_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000005013 89.0
CMS3_k127_53378_3 - - - - 0.0000000000002929 73.0
CMS3_k127_5386074_0 twitching motility protein K02670 - - 2.711e-197 626.0
CMS3_k127_5386074_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 552.0
CMS3_k127_5386074_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 435.0
CMS3_k127_5386074_3 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 422.0
CMS3_k127_5386074_4 Belongs to the protein N5-glutamine methyltransferase family K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 409.0
CMS3_k127_5386074_5 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000003544 204.0
CMS3_k127_541827_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1360.0
CMS3_k127_541827_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 396.0
CMS3_k127_5440889_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 2.209e-215 677.0
CMS3_k127_5440889_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 5.632e-203 635.0
CMS3_k127_5440889_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 480.0
CMS3_k127_5440889_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000004605 198.0
CMS3_k127_5441283_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.101e-304 939.0
CMS3_k127_5441283_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 587.0
CMS3_k127_5441283_2 Histidine kinase K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 565.0
CMS3_k127_5441283_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 369.0
CMS3_k127_5441283_4 Rard protein K05786 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005574 290.0
CMS3_k127_5441283_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000002737 81.0
CMS3_k127_5441283_6 Protein of unknown function, DUF485 - - - 0.000000000001958 72.0
CMS3_k127_551802_0 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000004906 206.0
CMS3_k127_5535057_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2383.0
CMS3_k127_5535057_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1171.0
CMS3_k127_5535057_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 318.0
CMS3_k127_5535057_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005067 271.0
CMS3_k127_5535057_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003483 246.0
CMS3_k127_5535057_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000151 88.0
CMS3_k127_5564116_0 carbohydrate binding - - - 0.0 4052.0
CMS3_k127_5564116_1 PAS domain K13924 - 2.1.1.80,3.1.1.61 5.516e-316 990.0
CMS3_k127_5564116_10 Acetyltransferase (GNAT) domain - - - 0.0000007572 60.0
CMS3_k127_5564116_11 IS66 C-terminal element K07484 - - 0.00008467 50.0
CMS3_k127_5564116_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 400.0
CMS3_k127_5564116_3 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 374.0
CMS3_k127_5564116_4 Peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 372.0
CMS3_k127_5564116_5 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 290.0
CMS3_k127_5564116_6 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001754 264.0
CMS3_k127_5564116_7 UPF0056 membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000001473 203.0
CMS3_k127_5564116_8 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000455 192.0
CMS3_k127_5564116_9 Metal dependent phosphohydrolases with conserved 'HD' motif. K03698 - - 0.00000000000003457 78.0
CMS3_k127_559089_0 TIGRFAM methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 9.504e-271 840.0
CMS3_k127_559089_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 482.0
CMS3_k127_559089_2 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 362.0
CMS3_k127_559089_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090,K18916 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81,1.20.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 362.0
CMS3_k127_559089_4 Bacterial transcriptional repressor C-terminal K16137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000099 253.0
CMS3_k127_5609205_0 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 484.0
CMS3_k127_5609205_1 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001777 273.0
CMS3_k127_5609205_2 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000006113 109.0
CMS3_k127_5641649_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 3.837e-230 731.0
CMS3_k127_5641649_1 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 292.0
CMS3_k127_5641649_2 protein involved in tolerance to divalent cations K03926 - - 0.0000000000000000000000000000000005407 138.0
CMS3_k127_5643044_0 type 4 pilus biogenesis protein K02656 - - 0.000000000000000000000000000000000000000000000000000000000000000000005651 244.0
CMS3_k127_5643044_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000001917 196.0
CMS3_k127_5643044_2 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000006938 111.0
CMS3_k127_5687134_0 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 9.334e-267 824.0
CMS3_k127_5687134_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 8.591e-247 782.0
CMS3_k127_5687134_10 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 452.0
CMS3_k127_5687134_11 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 437.0
CMS3_k127_5687134_12 Homocysteine S-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 422.0
CMS3_k127_5687134_13 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 401.0
CMS3_k127_5687134_14 Belongs to the ClpA ClpB family K03694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 349.0
CMS3_k127_5687134_15 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000005039 187.0
CMS3_k127_5687134_16 YCII-related domain - - - 0.00000000000000000000000000000000000000000000002027 183.0
CMS3_k127_5687134_17 MerR, DNA binding K19591,K19592 - - 0.0000000000000000000000000000000000000000000003126 175.0
CMS3_k127_5687134_18 YCII-related domain - - - 0.00000000000000000000000000000000000000000001894 166.0
CMS3_k127_5687134_19 glyoxalase III activity - - - 0.00000000000000000000000000000000000003076 148.0
CMS3_k127_5687134_2 Tripartite tricarboxylate transporter TctA family - - - 8.756e-234 742.0
CMS3_k127_5687134_20 ThiS family K03636 - - 0.00000000000000000000000001607 115.0
CMS3_k127_5687134_21 Transcriptional regulator K13794 - - 0.00000000000000000000000364 108.0
CMS3_k127_5687134_3 CoA-transferase family III - - - 4.008e-220 686.0
CMS3_k127_5687134_4 protein related to plant photosystem II stability assembly factor - - - 1.002e-209 658.0
CMS3_k127_5687134_5 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 556.0
CMS3_k127_5687134_6 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 545.0
CMS3_k127_5687134_7 AcnD-accessory protein PrpF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 490.0
CMS3_k127_5687134_8 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 496.0
CMS3_k127_5687134_9 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 481.0
CMS3_k127_5709248_0 Amino acid ABC transporter substrate-binding protein K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 520.0
CMS3_k127_5709248_1 acid transport system permease K09970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 509.0
CMS3_k127_5709248_2 Binding-protein-dependent transport system inner membrane component K02029,K09971,K10002,K10037 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 500.0
CMS3_k127_5709248_3 COG1126 ABC-type polar amino acid transport system, ATPase component K02028,K09972 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 303.0
CMS3_k127_5730276_0 twitching motility protein K02670 - - 1.183e-219 685.0
CMS3_k127_5730276_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000001609 159.0
CMS3_k127_5761655_0 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 5.361e-208 666.0
CMS3_k127_5761655_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 614.0
CMS3_k127_5761655_10 Flagellar hook-basal body K02408 - - 0.00000000000000000000000000000001247 129.0
CMS3_k127_5761655_11 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000004279 113.0
CMS3_k127_5761655_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 436.0
CMS3_k127_5761655_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 385.0
CMS3_k127_5761655_4 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004518 280.0
CMS3_k127_5761655_5 Phasin protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001333 261.0
CMS3_k127_5761655_6 His Kinase A (phosphoacceptor) domain K10942 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000429 261.0
CMS3_k127_5761655_7 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000007244 217.0
CMS3_k127_5761655_8 Phasin protein - - - 0.0000000000000000000000000000000000000000000000000000000009616 207.0
CMS3_k127_5761655_9 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000005039 173.0
CMS3_k127_5816996_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 3.628e-217 680.0
CMS3_k127_5816996_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.338e-201 635.0
CMS3_k127_5816996_10 protein conserved in bacteria K09937 - - 0.000000000000000000002483 94.0
CMS3_k127_5816996_11 Domain of unknown function (DUF4115) K15539 - - 0.000000006915 62.0
CMS3_k127_5816996_12 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00001017 47.0
CMS3_k127_5816996_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 605.0
CMS3_k127_5816996_3 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 587.0
CMS3_k127_5816996_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 501.0
CMS3_k127_5816996_5 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 490.0
CMS3_k127_5816996_6 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 441.0
CMS3_k127_5816996_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 345.0
CMS3_k127_5816996_8 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000003639 214.0
CMS3_k127_5816996_9 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000000003398 152.0
CMS3_k127_5818120_0 flagellar motor switch protein K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 527.0
CMS3_k127_5818120_1 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 517.0
CMS3_k127_5818120_11 OmpA family K03286 - - 0.0000000005149 61.0
CMS3_k127_5818120_2 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 334.0
CMS3_k127_5818120_3 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002034 265.0
CMS3_k127_5818120_4 Flagellar motor switch K02417 - - 0.0000000000000000000000000000000000000000000000000000004397 195.0
CMS3_k127_5818120_5 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000002453 132.0
CMS3_k127_5818120_6 Flagellar export protein FliJ K02413 - - 0.00000000000000000000000000000005476 136.0
CMS3_k127_5818120_7 Role in flagellar biosynthesis K02420 - - 0.000000000000000000000000000000197 126.0
CMS3_k127_5818120_8 Flagellar hook-length control protein FliK K02414 - - 0.0000000000000000000000000005539 126.0
CMS3_k127_5818120_9 flagellar K02418 - - 0.000000000000000000000012 107.0
CMS3_k127_5862408_0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 428.0
CMS3_k127_5862408_1 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 385.0
CMS3_k127_5862408_2 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000719 240.0
CMS3_k127_5862408_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000714 175.0
CMS3_k127_5862408_4 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.000000000000000000000000000000000006296 138.0
CMS3_k127_5862408_5 ATP synthase I chain K02116 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000292 109.0
CMS3_k127_5872850_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 430.0
CMS3_k127_5872850_1 COG1538 Outer membrane protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 398.0
CMS3_k127_5872850_2 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000008448 123.0
CMS3_k127_5878986_0 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 457.0
CMS3_k127_5878986_1 Polycystin cation channel K08714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 300.0
CMS3_k127_5930548_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 5.065e-259 816.0
CMS3_k127_5930548_1 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 1.519e-249 786.0
CMS3_k127_5930548_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 577.0
CMS3_k127_5930548_3 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 310.0
CMS3_k127_5930548_4 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000003185 187.0
CMS3_k127_5930548_5 Protein conserved in bacteria - - - 0.000000000000000000000000000000000001486 153.0
CMS3_k127_5964006_0 High-affinity nickel-transport protein K07241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 315.0
CMS3_k127_5964006_1 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 293.0
CMS3_k127_5964006_2 Belongs to the UPF0502 family K09915 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000005954 256.0
CMS3_k127_5964006_4 Protein of unknown function (DUF423) - - - 0.000000000000000000001189 102.0
CMS3_k127_5964006_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000001039 59.0
CMS3_k127_5976426_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 1.569e-248 778.0
CMS3_k127_5976426_1 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000000000000000001623 183.0
CMS3_k127_5976426_2 - - - - 0.00000000000000000000000000000007968 130.0
CMS3_k127_5976426_3 - - - - 0.0000000000000000003293 92.0
CMS3_k127_5976426_4 Belongs to the HesB IscA family K13628 - - 0.00000000000002402 72.0
CMS3_k127_6002701_0 Flagellar hook protein FlgE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 454.0
CMS3_k127_6002701_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 341.0
CMS3_k127_6002701_10 Anti-sigma-28 factor, FlgM K02398 - - 0.00000000004746 66.0
CMS3_k127_6002701_11 FlgN protein K02399 - - 0.000000002953 64.0
CMS3_k127_6002701_2 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 341.0
CMS3_k127_6002701_3 Flagellar motor protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003308 276.0
CMS3_k127_6002701_4 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000000000000000000000000001243 211.0
CMS3_k127_6002701_5 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000000000000000000000000000000000178 203.0
CMS3_k127_6002701_6 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000003197 179.0
CMS3_k127_6002701_7 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.0000000000000000000000000000000000000000002725 168.0
CMS3_k127_6002701_8 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000004051 138.0
CMS3_k127_6002701_9 basal body rod protein K02391 - - 0.0000000000000000000000001089 106.0
CMS3_k127_604152_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.188e-243 756.0
CMS3_k127_604152_1 phosphate K03306 - - 1.537e-229 722.0
CMS3_k127_604152_10 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 417.0
CMS3_k127_604152_11 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 400.0
CMS3_k127_604152_12 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 358.0
CMS3_k127_604152_13 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 353.0
CMS3_k127_604152_14 of murein hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 341.0
CMS3_k127_604152_15 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 332.0
CMS3_k127_604152_16 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 328.0
CMS3_k127_604152_17 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 311.0
CMS3_k127_604152_18 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 314.0
CMS3_k127_604152_19 Sulphur oxidation protein SoxZ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004918 275.0
CMS3_k127_604152_2 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 603.0
CMS3_k127_604152_20 Protein of unknown function (DUF938) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004017 277.0
CMS3_k127_604152_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000194 236.0
CMS3_k127_604152_22 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000006944 201.0
CMS3_k127_604152_23 - - - - 0.0000000000000000000000000000000000000000000000000000003351 199.0
CMS3_k127_604152_24 Pfam cytochrome c K08738 - - 0.00000000000000000000000000000000000000000000001752 173.0
CMS3_k127_604152_25 COG0491 Zn-dependent hydrolases, including glyoxylases K01138 - - 0.0000000000000000000000000000000000000000000005179 173.0
CMS3_k127_604152_27 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000001325 168.0
CMS3_k127_604152_28 effector of murein hydrolase LrgA K06518 - - 0.00000000000000000000000000000000006566 138.0
CMS3_k127_604152_29 Dioxygenase - - - 0.0000000000000000000000000000000001694 152.0
CMS3_k127_604152_3 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 581.0
CMS3_k127_604152_30 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000001533 126.0
CMS3_k127_604152_31 Endoribonuclease L-PSP - - - 0.00000000000000000000000007061 115.0
CMS3_k127_604152_32 activator of osmoprotectant transporter ProP K03607 - - 0.000000000000000000000001346 113.0
CMS3_k127_604152_33 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000646 104.0
CMS3_k127_604152_34 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.000000000295 70.0
CMS3_k127_604152_4 protein conserved in bacteria K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 571.0
CMS3_k127_604152_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 544.0
CMS3_k127_604152_6 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 495.0
CMS3_k127_604152_7 40-residue YVTN family beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008186 460.0
CMS3_k127_604152_8 mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 457.0
CMS3_k127_604152_9 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 426.0
CMS3_k127_6055337_0 argininosuccinate lyase K01755 - 4.3.2.1 2.726e-244 760.0
CMS3_k127_6055337_1 serine threonine protein kinase K12132 - 2.7.11.1 3.812e-194 615.0
CMS3_k127_6055337_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 7.674e-194 613.0
CMS3_k127_6055337_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 535.0
CMS3_k127_6055337_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 460.0
CMS3_k127_6055337_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 331.0
CMS3_k127_6055337_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000001318 151.0
CMS3_k127_6055337_7 alginate biosynthesis protein AlgZ FimS K08082 - 2.7.13.3 0.000000000002435 74.0
CMS3_k127_6072232_0 FAD-dependent pyridine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 537.0
CMS3_k127_6072232_1 Mut7-C ubiquitin - - - 0.0000000000000000000000000009205 117.0
CMS3_k127_6072232_2 - - - - 0.00000005093 59.0
CMS3_k127_6119059_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 1.991e-279 862.0
CMS3_k127_6119059_1 Hemerythrin-like metal-binding protein K07216 - - 0.000000000000000000000000000000000000000000000000005467 190.0
CMS3_k127_6119059_2 - - - - 0.00000000000000000000000003323 108.0
CMS3_k127_6119059_3 Bacterial protein of unknown function (DUF924) - - - 0.0000000002562 60.0
CMS3_k127_6121709_0 PUA-like domain K00958 - 2.7.7.4 1.462e-221 692.0
CMS3_k127_6121709_1 FAD binding domain K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000098 440.0
CMS3_k127_6121709_2 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 317.0
CMS3_k127_6121709_3 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008663 251.0
CMS3_k127_6121709_4 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000002987 178.0
CMS3_k127_6121709_5 oxidation protein K17227 - - 0.00000000000000000000000000000000000000000001022 164.0
CMS3_k127_6121709_6 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000372 146.0
CMS3_k127_6121709_7 Sulfurtransferase TusA K04085 - - 0.0000000000000000000000000000003074 126.0
CMS3_k127_6148870_0 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 582.0
CMS3_k127_6148870_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 397.0
CMS3_k127_6148870_2 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 395.0
CMS3_k127_6148870_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000004992 238.0
CMS3_k127_6148870_4 UbiA prenyltransferase family K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000005733 184.0
CMS3_k127_6227640_0 glutaminyl-tRNA K01886 - 6.1.1.18 1.889e-312 968.0
CMS3_k127_6227640_1 S4 RNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 355.0
CMS3_k127_6227640_2 Virulence factor BrkB - - - 0.00000000000000000000000000000000000000000000000000000000000000001219 244.0
CMS3_k127_6227640_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000000000005046 177.0
CMS3_k127_6227640_4 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000004139 164.0
CMS3_k127_6235350_0 PrkA family serine protein kinase K07180 - - 0.0 1150.0
CMS3_k127_6235350_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.395e-284 888.0
CMS3_k127_6235350_2 SpoVR family - - - 1.355e-251 783.0
CMS3_k127_6235350_3 Protein of unknown function (DUF444) K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 524.0
CMS3_k127_6235350_4 TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 456.0
CMS3_k127_6235350_5 Domain of unknown function (DUF1850) - - - 0.000000000000000000000000000000000002726 159.0
CMS3_k127_6235350_6 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K00404 - 1.9.3.1 0.00000000000000000000000008366 111.0
CMS3_k127_6235350_7 Belongs to the RNase T2 family K01166 - 3.1.27.1 0.000000000000003574 80.0
CMS3_k127_6235350_8 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000007303 63.0
CMS3_k127_6235350_9 NmrA-like family - - - 0.00005664 49.0
CMS3_k127_63523_0 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 591.0
CMS3_k127_63523_1 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 599.0
CMS3_k127_63523_10 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000000000000000002711 153.0
CMS3_k127_63523_11 Protein of unknown function (DUF3135) - - - 0.000000000001478 73.0
CMS3_k127_63523_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 472.0
CMS3_k127_63523_3 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 473.0
CMS3_k127_63523_4 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 350.0
CMS3_k127_63523_5 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 285.0
CMS3_k127_63523_6 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000009471 246.0
CMS3_k127_63523_7 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004624 238.0
CMS3_k127_63523_8 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000002607 205.0
CMS3_k127_63523_9 - - - - 0.0000000000000000000000000000000000000008112 153.0
CMS3_k127_635547_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 3.445e-221 691.0
CMS3_k127_635547_1 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 336.0
CMS3_k127_635547_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 315.0
CMS3_k127_635547_3 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000001242 212.0
CMS3_k127_635547_4 FecR protein - - - 0.000001297 52.0
CMS3_k127_6362125_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000003824 256.0
CMS3_k127_6362125_1 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000003571 201.0
CMS3_k127_6362125_2 LemA family - - - 0.00000000000000000000000000000000000000000004589 168.0
CMS3_k127_6362125_3 DNA-binding transcription factor activity - - - 0.000000000000000000000000001421 115.0
CMS3_k127_6362125_4 FtsX-like permease family K02004 - - 0.000000000000001808 78.0
CMS3_k127_6365203_0 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 349.0
CMS3_k127_6365203_1 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 312.0
CMS3_k127_6365203_2 Protein of unknown function (DUF938) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001785 259.0
CMS3_k127_6365203_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000001026 64.0
CMS3_k127_6400242_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 406.0
CMS3_k127_6400242_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 394.0
CMS3_k127_6400242_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004334 279.0
CMS3_k127_6400242_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000004148 136.0
CMS3_k127_6400242_4 MacB-like periplasmic core domain K02004 - - 0.00000000002586 73.0
CMS3_k127_6405463_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1056.0
CMS3_k127_6405463_1 Exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 7.408e-202 642.0
CMS3_k127_6405463_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 595.0
CMS3_k127_6420067_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1685.0
CMS3_k127_6420067_1 Domain of unknown function (DUF3394) - - - 0.0 1263.0
CMS3_k127_6420067_2 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 521.0
CMS3_k127_6420067_3 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001973 232.0
CMS3_k127_6420067_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000006154 98.0
CMS3_k127_642718_0 COG0841 Cation multidrug efflux pump K03296,K18138 - - 0.0 1631.0
CMS3_k127_642718_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 418.0
CMS3_k127_642718_2 Co Zn Cd efflux system component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001298 280.0
CMS3_k127_642718_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009405 288.0
CMS3_k127_642718_4 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000129 267.0
CMS3_k127_642718_5 MAATS-type transcriptional repressor, C-terminal region K03577 - - 0.0000000000000000000000000000000000000000000000000000000002255 212.0
CMS3_k127_6446471_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 1.196e-235 732.0
CMS3_k127_6446471_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 554.0
CMS3_k127_6446471_10 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000005546 206.0
CMS3_k127_6446471_11 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047631,GO:0050896 3.6.1.13 0.0000000000000000000000000000000000000000000000000000002212 203.0
CMS3_k127_6446471_12 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000000000000000000000001536 194.0
CMS3_k127_6446471_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000001678 169.0
CMS3_k127_6446471_2 hydroxypyruvate reductase K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 537.0
CMS3_k127_6446471_3 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 353.0
CMS3_k127_6446471_4 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 349.0
CMS3_k127_6446471_5 B12 binding domain K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 314.0
CMS3_k127_6446471_6 COG0846 NAD-dependent protein deacetylases, SIR2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 286.0
CMS3_k127_6446471_7 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002054 269.0
CMS3_k127_6446471_8 Glutathione peroxidase K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000002751 249.0
CMS3_k127_6446471_9 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000001577 252.0
CMS3_k127_6453075_0 Receptor family ligand binding region K01999 - - 1.925e-194 614.0
CMS3_k127_6453075_1 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 524.0
CMS3_k127_6453075_10 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 327.0
CMS3_k127_6453075_11 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 274.0
CMS3_k127_6453075_12 membrane K08973 - - 0.0000000000000000000000000000000000000000000000000000000000004563 217.0
CMS3_k127_6453075_13 Cytochrome c K08738 - - 0.000000000000000000000000000000000000000005261 156.0
CMS3_k127_6453075_14 Planctomycete cytochrome C - - - 0.0000000000000000003264 93.0
CMS3_k127_6453075_15 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000000000002533 86.0
CMS3_k127_6453075_2 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 513.0
CMS3_k127_6453075_3 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 482.0
CMS3_k127_6453075_4 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 428.0
CMS3_k127_6453075_5 branched-chain amino acid K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 421.0
CMS3_k127_6453075_6 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 425.0
CMS3_k127_6453075_7 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 406.0
CMS3_k127_6453075_8 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 349.0
CMS3_k127_6453075_9 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 337.0
CMS3_k127_6495110_0 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000003384 125.0
CMS3_k127_6495110_1 RnfH family Ubiquitin K09801 - - 0.000000000000000000000000000001773 128.0
CMS3_k127_6495110_2 COG3039 Transposase and inactivated derivatives IS5 family K07481 - - 0.00000000000008506 77.0
CMS3_k127_6504393_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001895 266.0
CMS3_k127_6504393_1 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009522 269.0
CMS3_k127_6504393_2 Cytochrome c K08738 - - 0.0000000000000000005438 91.0
CMS3_k127_6514365_0 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 316.0
CMS3_k127_6514365_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000002895 199.0
CMS3_k127_6514365_2 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000006541 142.0
CMS3_k127_6514365_3 Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA K18383 - 4.1.2.41,4.2.1.101 0.000000000000000000000000001004 115.0
CMS3_k127_6514365_4 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K06016 - 3.5.1.6,3.5.1.87 0.000000000000001897 76.0
CMS3_k127_6550676_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 539.0
CMS3_k127_6550676_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 510.0
CMS3_k127_6550676_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 379.0
CMS3_k127_6550676_3 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 351.0
CMS3_k127_6550676_4 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000000000000000001954 226.0
CMS3_k127_6550676_5 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000002152 228.0
CMS3_k127_6550676_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000000004328 186.0
CMS3_k127_6550676_7 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000005865 149.0
CMS3_k127_6550676_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000001814 85.0
CMS3_k127_6619945_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2573.0
CMS3_k127_6619945_1 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 293.0
CMS3_k127_6633413_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1031.0
CMS3_k127_6633413_1 COG2199 FOG GGDEF domain K07212,K07216 - - 0.0000000000000000000002538 104.0
CMS3_k127_665240_0 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 576.0
CMS3_k127_665240_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 534.0
CMS3_k127_665240_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002777 279.0
CMS3_k127_665240_3 Smr protein MutS2 - - - 0.00000000000000000000000000000000000000000002329 172.0
CMS3_k127_665240_4 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000008839 144.0
CMS3_k127_6786401_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1094.0
CMS3_k127_6786401_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.1e-238 740.0
CMS3_k127_6786401_2 Peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 605.0
CMS3_k127_6786401_3 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 332.0
CMS3_k127_6786401_4 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.000000000000000000000000000000000000000000000000000000007713 206.0
CMS3_k127_6826971_0 Sodium:solute symporter family K14393 - - 9.964e-313 976.0
CMS3_k127_6826971_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.071e-278 874.0
CMS3_k127_6826971_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 1.135e-246 778.0
CMS3_k127_6826971_3 Domain of unknown function (DUF4212) - - - 0.0000000000000000000000000000000000002706 143.0
CMS3_k127_6826971_4 DNA polymerase III, epsilon K02342 - 2.7.7.7 0.0000000000000000000000000000000000005733 157.0
CMS3_k127_6826971_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000007943 123.0
CMS3_k127_6826971_6 SMART Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000001163 109.0
CMS3_k127_6846359_0 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 601.0
CMS3_k127_6846359_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 547.0
CMS3_k127_6846359_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 332.0
CMS3_k127_6846359_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 305.0
CMS3_k127_6846359_4 Inositol-1-monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 313.0
CMS3_k127_6846359_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000001241 242.0
CMS3_k127_6877215_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1035.0
CMS3_k127_6877215_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 405.0
CMS3_k127_6877215_10 LysE type translocator K05834 - - 0.0000000000000000000000000000000000000000000000000000000000000004414 226.0
CMS3_k127_6877215_11 peptidase S16 K07157 - - 0.000000000000000000000000000000000000000000000000000000000002861 216.0
CMS3_k127_6877215_12 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000001464 201.0
CMS3_k127_6877215_13 Uracil-DNA glycosylase superfamily K03649 - 3.2.2.28 0.0000000000000000000000000000000000000002617 162.0
CMS3_k127_6877215_15 NusG domain II - - - 0.000000000000000000000000000000000000761 147.0
CMS3_k127_6877215_17 Histidine kinase - - - 0.00000000000000000004327 103.0
CMS3_k127_6877215_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 377.0
CMS3_k127_6877215_3 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 345.0
CMS3_k127_6877215_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 325.0
CMS3_k127_6877215_5 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 291.0
CMS3_k127_6877215_6 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000285 282.0
CMS3_k127_6877215_7 DNA polymerase III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001058 251.0
CMS3_k127_6877215_8 PFAM pentapeptide repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000165 243.0
CMS3_k127_6877215_9 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000000000000000000000000000000000000004275 235.0
CMS3_k127_6896991_0 L-serine dehydratase K01752 - 4.3.1.17 3.171e-242 756.0
CMS3_k127_6896991_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.128e-228 716.0
CMS3_k127_6896991_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 443.0
CMS3_k127_6896991_3 protein conserved in bacteria K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 440.0
CMS3_k127_6896991_4 mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 378.0
CMS3_k127_6896991_5 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 349.0
CMS3_k127_6896991_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001634 273.0
CMS3_k127_6896991_7 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000293 286.0
CMS3_k127_6896991_8 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000000000009616 195.0
CMS3_k127_6896991_9 - - - - 0.00000000000000000000000000000000000001318 147.0
CMS3_k127_6915078_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 6.138e-309 953.0
CMS3_k127_69339_0 Histidine kinase K10715,K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 498.0
CMS3_k127_69339_1 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 444.0
CMS3_k127_69339_2 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 321.0
CMS3_k127_69339_3 Pfam Enoyl-CoA hydratase isomerase K13816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003443 274.0
CMS3_k127_69339_4 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000002352 200.0
CMS3_k127_69339_5 HD domain K13815 - - 0.0000000000000000000000000000000000000000000000000302 183.0
CMS3_k127_69339_6 PFAM LemA family K03744 - - 0.00000000000000000000000000000000000000139 154.0
CMS3_k127_69339_7 FecR protein - - - 0.0000000000000000000000000001278 130.0
CMS3_k127_69806_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1026.0
CMS3_k127_69806_1 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 574.0
CMS3_k127_69806_2 NAD(P) transhydrogenase, alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 480.0
CMS3_k127_6994692_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 8.333e-276 854.0
CMS3_k127_6994692_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 528.0
CMS3_k127_7058217_0 COG1199 Rad3-related DNA helicases K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 551.0
CMS3_k127_7058217_1 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000002884 213.0
CMS3_k127_7058217_2 VRR_NUC - - - 0.000000000000000000000000000000000000000000000000000002428 203.0
CMS3_k127_7058217_3 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000002997 153.0
CMS3_k127_7079385_0 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 351.0
CMS3_k127_7079385_1 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 333.0
CMS3_k127_7079385_10 MOSC domain - - - 0.00000000000000000000000000000000000000000002449 168.0
CMS3_k127_7079385_11 - - - - 0.000000000000000000000000000000000002662 147.0
CMS3_k127_7079385_12 TfoX N-terminal domain - - - 0.0000000000000000000000000000000001456 137.0
CMS3_k127_7079385_13 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000003189 130.0
CMS3_k127_7079385_14 Alanine racemase, C-terminal domain K01775 - 5.1.1.1 0.0000000000000000000001447 99.0
CMS3_k127_7079385_15 RibD C-terminal domain - - - 0.0000000000004212 68.0
CMS3_k127_7079385_16 - - - - 0.00005216 52.0
CMS3_k127_7079385_2 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 325.0
CMS3_k127_7079385_3 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 317.0
CMS3_k127_7079385_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004508 281.0
CMS3_k127_7079385_5 Dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006526 272.0
CMS3_k127_7079385_6 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000000000000000000000003917 234.0
CMS3_k127_7079385_7 Domain of unknown function (DUF4396) - - - 0.00000000000000000000000000000000000000000000000000000000000000001443 228.0
CMS3_k127_7079385_8 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000001308 211.0
CMS3_k127_7079385_9 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000000000648 173.0
CMS3_k127_7093568_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 6.705e-300 925.0
CMS3_k127_7093568_1 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 2.045e-225 719.0
CMS3_k127_7093568_2 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 601.0
CMS3_k127_7093568_3 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 442.0
CMS3_k127_7093568_4 Scaffold protein Nfu NifU - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 291.0
CMS3_k127_7093568_5 TIGRFAM SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003838 271.0
CMS3_k127_7093568_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000003289 179.0
CMS3_k127_7093568_7 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000006271 181.0
CMS3_k127_7095463_0 histidine kinase A domain protein - - - 0.0 1204.0
CMS3_k127_7095463_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1197.0
CMS3_k127_7095463_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 336.0
CMS3_k127_7095463_11 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 310.0
CMS3_k127_7095463_12 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 299.0
CMS3_k127_7095463_13 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001314 259.0
CMS3_k127_7095463_14 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000365 195.0
CMS3_k127_7095463_15 - - - - 0.00000000000001593 75.0
CMS3_k127_7095463_2 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 0.0 1116.0
CMS3_k127_7095463_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.051e-307 945.0
CMS3_k127_7095463_4 ABC-type Fe3 transport system, permease component K02011 - - 1.955e-240 757.0
CMS3_k127_7095463_5 DNA polymerase III K02342 - 2.7.7.7 2.469e-229 731.0
CMS3_k127_7095463_6 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 531.0
CMS3_k127_7095463_7 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 490.0
CMS3_k127_7095463_8 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 448.0
CMS3_k127_7095463_9 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 363.0
CMS3_k127_7110648_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 1.103e-301 935.0
CMS3_k127_7110648_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.196e-228 710.0
CMS3_k127_7110648_10 DNA replication, recombination and repair K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004171 272.0
CMS3_k127_7110648_11 response regulator K11712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004293 263.0
CMS3_k127_7110648_12 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000006588 241.0
CMS3_k127_7110648_13 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000001749 254.0
CMS3_k127_7110648_14 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000000000005571 226.0
CMS3_k127_7110648_15 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000000000009168 205.0
CMS3_k127_7110648_16 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.00000000000000000000000000000000000000000000000000001194 192.0
CMS3_k127_7110648_17 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.000000000000000000000000000000000000000000000001257 179.0
CMS3_k127_7110648_18 His Kinase A (phosphoacceptor) domain K11711 - 2.7.13.3 0.000000000000000000000000000000007901 132.0
CMS3_k127_7110648_19 FeS assembly protein IscX - - - 0.0000000000000000000000000001107 116.0
CMS3_k127_7110648_2 His Kinase A (phosphoacceptor) domain K11711 - 2.7.13.3 2.809e-202 651.0
CMS3_k127_7110648_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 545.0
CMS3_k127_7110648_4 Cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 436.0
CMS3_k127_7110648_5 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 400.0
CMS3_k127_7110648_6 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 383.0
CMS3_k127_7110648_7 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 349.0
CMS3_k127_7110648_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 313.0
CMS3_k127_7110648_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 307.0
CMS3_k127_7115148_0 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 407.0
CMS3_k127_7115148_1 acetyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004107 287.0
CMS3_k127_7115148_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000002441 207.0
CMS3_k127_7151601_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1645.0
CMS3_k127_7151601_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 2.88e-287 889.0
CMS3_k127_7151601_2 Zinc-binding dehydrogenase K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 540.0
CMS3_k127_7151601_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 323.0
CMS3_k127_7151601_4 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003682 276.0
CMS3_k127_7151601_5 PFAM lipolytic protein G-D-S-L family K01073 - 3.1.2.20 0.000000000000000000000000000000000000000000000000165 183.0
CMS3_k127_7151601_6 Bacterial transcriptional repressor C-terminal K16137 - - 0.0000000000000000000000001923 107.0
CMS3_k127_7180877_0 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 6.751e-250 799.0
CMS3_k127_7180877_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 519.0
CMS3_k127_7180877_2 COG0569 K transport systems, NAD-binding component K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 497.0
CMS3_k127_7180877_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 384.0
CMS3_k127_7180877_4 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000001033 152.0
CMS3_k127_7185379_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 2.101e-222 702.0
CMS3_k127_7185379_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 608.0
CMS3_k127_7185379_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000009854 158.0
CMS3_k127_7210068_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06020 - 3.6.3.25 2.186e-310 956.0
CMS3_k127_7210068_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 400.0
CMS3_k127_7210068_2 branched-chain amino acid permease (azaleucine resistance) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 293.0
CMS3_k127_7210068_3 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000005273 191.0
CMS3_k127_7210068_4 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000000000000008392 115.0
CMS3_k127_7221669_0 Carboxyl transferase domain K01969 - 6.4.1.4 5.864e-276 861.0
CMS3_k127_7221669_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 584.0
CMS3_k127_7221669_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 552.0
CMS3_k127_7221669_3 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 348.0
CMS3_k127_7221669_4 carboxylase K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 0.000000000000000000000000000000000000000000000000000001367 200.0
CMS3_k127_7252422_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 8.406e-194 619.0
CMS3_k127_7252422_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 582.0
CMS3_k127_7252422_2 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 337.0
CMS3_k127_7252422_3 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002372 271.0
CMS3_k127_7252422_4 Belongs to the DnaA family K10763 - - 0.000000000000000000000000000000000000000000000000001717 205.0
CMS3_k127_7252422_5 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000005866 183.0
CMS3_k127_7252422_6 chemotaxis - - - 0.000000000000000000000005495 108.0
CMS3_k127_725349_0 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 381.0
CMS3_k127_725349_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000002925 214.0
CMS3_k127_725349_2 Tautomerase enzyme - - - 0.000000000000000000000000000000000000000000000000000000001975 202.0
CMS3_k127_725349_3 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000003391 165.0
CMS3_k127_7259137_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.671e-245 763.0
CMS3_k127_7259137_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.405e-243 754.0
CMS3_k127_7259137_10 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 309.0
CMS3_k127_7259137_11 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 303.0
CMS3_k127_7259137_12 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 283.0
CMS3_k127_7259137_13 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 282.0
CMS3_k127_7259137_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001686 280.0
CMS3_k127_7259137_15 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001496 276.0
CMS3_k127_7259137_16 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002777 272.0
CMS3_k127_7259137_17 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001242 245.0
CMS3_k127_7259137_18 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007353 227.0
CMS3_k127_7259137_19 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000000000002376 205.0
CMS3_k127_7259137_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.066e-224 709.0
CMS3_k127_7259137_20 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000001674 190.0
CMS3_k127_7259137_21 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000004934 182.0
CMS3_k127_7259137_22 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000007684 178.0
CMS3_k127_7259137_23 Protein of unknown function (DUF3579) - - - 0.00000000000000000000000000000000000007276 147.0
CMS3_k127_7259137_24 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000002029 132.0
CMS3_k127_7259137_25 Protein of unknown function (DUF2788) - - - 0.000000000000000000000000000003482 120.0
CMS3_k127_7259137_26 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000002262 120.0
CMS3_k127_7259137_27 - - - - 0.00000000000000000000003599 101.0
CMS3_k127_7259137_3 Belongs to the thiolase family K00626 - 2.3.1.9 8.654e-199 624.0
CMS3_k127_7259137_4 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 587.0
CMS3_k127_7259137_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 556.0
CMS3_k127_7259137_6 Zn-dependent protease with chaperone function K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 432.0
CMS3_k127_7259137_7 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 359.0
CMS3_k127_7259137_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 348.0
CMS3_k127_7259137_9 Phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 317.0
CMS3_k127_7272671_0 glycolate oxidase subunit GlcD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 524.0
CMS3_k127_7272671_1 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 335.0
CMS3_k127_7272671_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000008353 150.0
CMS3_k127_730234_0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000004315 117.0
CMS3_k127_730234_1 Domain of unknown function (DUF4142) - - - 0.00000000000002243 83.0
CMS3_k127_730234_2 - - - - 0.00002518 55.0
CMS3_k127_7331936_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 7.063e-250 776.0
CMS3_k127_7331936_1 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - 1.321e-228 722.0
CMS3_k127_7331936_10 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000000000000001464 212.0
CMS3_k127_7331936_11 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000003205 215.0
CMS3_k127_7331936_12 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000005717 178.0
CMS3_k127_7331936_13 HNH nucleases - - - 0.000000000000000000000000000000000000000132 153.0
CMS3_k127_7331936_14 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000253 148.0
CMS3_k127_7331936_15 Protein of unknown function (DUF2789) - - - 0.000000000000000000000000000006384 121.0
CMS3_k127_7331936_16 Cytochrome c - - - 0.000000000000000000001888 97.0
CMS3_k127_7331936_17 Zinc-finger domain - - - 0.00000000000000000002625 103.0
CMS3_k127_7331936_2 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 1.763e-226 713.0
CMS3_k127_7331936_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 619.0
CMS3_k127_7331936_4 outer membrane porin, OprD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 602.0
CMS3_k127_7331936_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 582.0
CMS3_k127_7331936_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 557.0
CMS3_k127_7331936_7 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 307.0
CMS3_k127_7331936_8 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009569 276.0
CMS3_k127_7331936_9 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001181 243.0
CMS3_k127_733897_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 318.0
CMS3_k127_733897_1 Phospholipase A1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000503 254.0
CMS3_k127_7353461_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.353e-214 672.0
CMS3_k127_7353461_1 Cache 3/Cache 2 fusion domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 608.0
CMS3_k127_7353461_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000001106 194.0
CMS3_k127_735752_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1050.0
CMS3_k127_735752_1 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 449.0
CMS3_k127_735752_2 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 367.0
CMS3_k127_735752_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002529 243.0
CMS3_k127_735752_4 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000001242 172.0
CMS3_k127_739620_0 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 561.0
CMS3_k127_739620_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 532.0
CMS3_k127_739620_2 epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 386.0
CMS3_k127_739620_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 314.0
CMS3_k127_739620_4 Alpha beta hydrolase K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000002149 267.0
CMS3_k127_739620_5 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000001452 181.0
CMS3_k127_739620_6 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000006466 155.0
CMS3_k127_7453032_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1116.0
CMS3_k127_7453032_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004243 278.0
CMS3_k127_7453032_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000001059 162.0
CMS3_k127_7538453_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 601.0
CMS3_k127_7538453_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 562.0
CMS3_k127_7538453_2 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 378.0
CMS3_k127_7538453_3 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 380.0
CMS3_k127_7538453_4 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005759 275.0
CMS3_k127_7538453_5 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000000000007577 166.0
CMS3_k127_7538453_6 - - - - 0.000000000000000000000000000000003233 132.0
CMS3_k127_7538453_7 Chalcone isomerase-like - - - 0.000000000000000000000000004557 118.0
CMS3_k127_7538453_8 - - - - 0.000000000000000000000001707 106.0
CMS3_k127_757089_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001411 245.0
CMS3_k127_757089_1 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000002137 199.0
CMS3_k127_757089_2 Domain of unknown function (DUF4398) - - - 0.000000000837 64.0
CMS3_k127_757089_3 UPF0391 membrane protein - - - 0.00000002131 61.0
CMS3_k127_7589086_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 1.844e-224 698.0
CMS3_k127_7589086_1 4Fe-4S binding domain K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 391.0
CMS3_k127_7589086_2 MauM NapG family ferredoxin-type protein K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 353.0
CMS3_k127_7589086_3 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000000000000000000000000000000000006833 174.0
CMS3_k127_7589086_4 cytochrome c-type protein K02569 - - 0.0000000002753 61.0
CMS3_k127_764007_0 Sulfite reductase K00381 - 1.8.1.2 2.106e-237 742.0
CMS3_k127_764007_1 Transcriptional regulator K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 399.0
CMS3_k127_764007_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 343.0
CMS3_k127_764007_3 Type IX secretion system membrane protein PorP/SprF - - - 0.0000000000000000000000000000000000000000000001094 185.0
CMS3_k127_764007_4 - - - - 0.0000000000007321 74.0
CMS3_k127_786801_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002675 276.0
CMS3_k127_786801_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004632 257.0
CMS3_k127_786801_2 response regulator K02483 - - 0.00000000002665 64.0
CMS3_k127_788356_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 551.0
CMS3_k127_788356_1 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 500.0
CMS3_k127_788356_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 399.0
CMS3_k127_788356_3 synthesis repressor, PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000159 258.0
CMS3_k127_798264_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 618.0
CMS3_k127_798264_1 NAD(P) transhydrogenase, alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000003145 243.0
CMS3_k127_798264_2 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000001004 150.0
CMS3_k127_798264_3 - - - - 0.00000234 50.0
CMS3_k127_847110_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 1.208e-304 940.0
CMS3_k127_847110_1 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 386.0
CMS3_k127_847110_2 Cytochrome C oxidase subunit II, transmembrane domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 296.0
CMS3_k127_847110_3 oxidase assembly K02258 - - 0.000000000000000000000000000000000000000000116 174.0
CMS3_k127_847110_4 Yip1 domain - - - 0.00000000000000000000000000000000000002634 151.0
CMS3_k127_865545_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1542.0
CMS3_k127_865545_1 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000000000000000000000000000002585 239.0
CMS3_k127_865545_2 Molybdopterin binding - - - 0.000000000001285 79.0
CMS3_k127_905432_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 609.0
CMS3_k127_905432_1 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 439.0
CMS3_k127_905432_10 - - - - 0.000000000000000000000000004915 115.0
CMS3_k127_905432_11 - - - - 0.0000001406 57.0
CMS3_k127_905432_2 Bacterial regulatory helix-turn-helix protein, lysR family K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 407.0
CMS3_k127_905432_3 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 326.0
CMS3_k127_905432_4 MOSC domain-containing protein-containing proteincontaining protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000742 269.0
CMS3_k127_905432_5 Cupin - - - 0.00000000000000000000000000000000000000000000001536 174.0
CMS3_k127_905432_6 MobA-like NTP transferase domain - - - 0.00000000000000000000000000000000000000000007367 175.0
CMS3_k127_905432_7 KTSC domain - - - 0.000000000000000000000000000000001848 131.0
CMS3_k127_905432_8 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000001389 125.0
CMS3_k127_905432_9 - - - - 0.0000000000000000000000000001561 121.0
CMS3_k127_916458_0 ACT domain K00928 - 2.7.2.4 1.32e-269 833.0
CMS3_k127_916458_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 9.913e-200 629.0
CMS3_k127_916458_2 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 522.0
CMS3_k127_916458_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 441.0
CMS3_k127_916458_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001176 286.0
CMS3_k127_916458_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000006592 153.0
CMS3_k127_916458_6 - - - - 0.00000000000000000000000000000000000004063 145.0
CMS3_k127_916458_7 Protein of unknown function (DUF465) - - - 0.000000000000000000005627 96.0
CMS3_k127_916458_8 Recombinase zinc beta ribbon domain - - - 0.0006651 42.0
CMS3_k127_952347_0 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000584 244.0
CMS3_k127_952347_1 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000003788 157.0
CMS3_k127_952347_2 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000002458 149.0
CMS3_k127_952347_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000001414 107.0
CMS3_k127_952347_4 protein conserved in bacteria - - - 0.000000000006347 68.0
CMS3_k127_952347_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0002117 51.0
CMS3_k127_975371_0 Multicopper oxidase K22350 - 1.16.3.3 2.406e-293 910.0
CMS3_k127_975371_1 Signal transduction histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 311.0
CMS3_k127_975371_2 COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 - - 0.000000000000000000000000000000000000000000000000000000000002861 216.0
CMS3_k127_975371_3 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000003388 217.0
CMS3_k127_975371_4 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000002151 158.0
CMS3_k127_975371_5 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000003405 132.0