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Overview

ID MAG00574
Name CMS3_bin.85
Sample SMP0012
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Nitrososphaeria
Order Nitrososphaerales
Family Nitrosopumilaceae
Genus Nitrosopumilus
Species
Assembly information
Completeness (%) 81.9
Contamination (%) 1.91
GC content (%) 33.0
N50 (bp) 9,164
Genome size (bp) 1,174,871

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1436

Gene name Description KEGG GOs EC E-value Score Sequence
CMS3_k127_1015867_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 0.0 1388.0
CMS3_k127_1015867_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1209.0
CMS3_k127_1015867_10 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 482.0
CMS3_k127_1015867_11 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 462.0
CMS3_k127_1015867_12 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 453.0
CMS3_k127_1015867_13 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 380.0
CMS3_k127_1015867_14 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 332.0
CMS3_k127_1015867_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 296.0
CMS3_k127_1015867_16 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002135 252.0
CMS3_k127_1015867_17 Peptidyl-tRNA hydrolase PTH2 K04794 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000006424 243.0
CMS3_k127_1015867_18 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006762 241.0
CMS3_k127_1015867_19 - K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002237 239.0
CMS3_k127_1015867_2 Radical SAM K04069 - 1.97.1.4 2.258e-241 745.0
CMS3_k127_1015867_20 metal-dependent protease of the PAD1 JAB1 superfamily K21140 - 3.13.1.6 0.0000000000000000000000000000000000000000000000000000000000000000027 227.0
CMS3_k127_1015867_21 Domain of unknown function (DUF2024) - - - 0.000000000000000000000000000000000000000000000000002378 182.0
CMS3_k127_1015867_22 - - - - 0.00000000000000000000000000000000000000000000001629 171.0
CMS3_k127_1015867_23 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000000000000000000000000000001189 148.0
CMS3_k127_1015867_24 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000002688 129.0
CMS3_k127_1015867_25 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.000000000000000000000000000000003069 128.0
CMS3_k127_1015867_26 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.00000000000000000000000000000002161 126.0
CMS3_k127_1015867_27 - - - - 0.0000000000000000000000000000009686 121.0
CMS3_k127_1015867_29 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000183 78.0
CMS3_k127_1015867_3 antibiotic catabolic process K18235 - - 1.401e-223 704.0
CMS3_k127_1015867_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 3.959e-219 683.0
CMS3_k127_1015867_5 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 3.157e-214 668.0
CMS3_k127_1015867_6 tRNA pseudouridine synthase K06176 - 5.4.99.27 2.543e-213 667.0
CMS3_k127_1015867_7 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 587.0
CMS3_k127_1015867_8 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 574.0
CMS3_k127_1015867_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 557.0
CMS3_k127_1038647_0 Sulfite reductase K00392 - 1.8.7.1 0.0 1002.0
CMS3_k127_104131_0 Ammonium Transporter K03320 - - 2.436e-233 723.0
CMS3_k127_104131_1 Adenylate guanylate cyclase with integral membrane sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 401.0
CMS3_k127_104131_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000001157 219.0
CMS3_k127_106106_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 2228.0
CMS3_k127_106106_1 Protein of unknown function DUF111 K09121 - 4.99.1.12 3.025e-207 649.0
CMS3_k127_106106_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 351.0
CMS3_k127_106106_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000002565 232.0
CMS3_k127_106106_12 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000000000000000000000000000000000000008543 165.0
CMS3_k127_106106_2 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 571.0
CMS3_k127_106106_3 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 522.0
CMS3_k127_106106_4 tRNA methyl transferase K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 457.0
CMS3_k127_106106_5 Cysteine desulfurase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 463.0
CMS3_k127_106106_6 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 455.0
CMS3_k127_106106_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 442.0
CMS3_k127_106106_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 420.0
CMS3_k127_106106_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 353.0
CMS3_k127_109237_0 TIGRFAM glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 - 2.6.1.16 0.0 1059.0
CMS3_k127_109237_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 329.0
CMS3_k127_109237_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 299.0
CMS3_k127_109237_3 - - - - 0.000000000000000000000000000000000009033 137.0
CMS3_k127_109237_4 Belongs to the UPF0284 family - - - 0.000000000000004136 79.0
CMS3_k127_111122_0 DEAD DEAH box helicase K05592 - 3.6.4.13 1.225e-257 797.0
CMS3_k127_111122_1 Mediates influx of magnesium ions K03284 - - 1.314e-250 782.0
CMS3_k127_111122_2 COG1651 Protein-disulfide isomerase K21990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 437.0
CMS3_k127_111122_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 377.0
CMS3_k127_111122_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001036 256.0
CMS3_k127_111122_5 - - - - 0.0000000000000000000000000000000000000000000000000000002946 194.0
CMS3_k127_111122_6 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000002191 126.0
CMS3_k127_1111578_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1499.0
CMS3_k127_1111578_1 - - - - 7.39e-202 632.0
CMS3_k127_1111578_2 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 - 2.1.1.260 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 385.0
CMS3_k127_1187336_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1095.0
CMS3_k127_1187336_1 Radical SAM K18285 - 2.5.1.120 1.835e-226 703.0
CMS3_k127_1187336_10 - - - - 0.00000000000000000000000000000000000002681 144.0
CMS3_k127_1187336_11 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000005078 129.0
CMS3_k127_1187336_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000008577 125.0
CMS3_k127_1187336_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 524.0
CMS3_k127_1187336_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 446.0
CMS3_k127_1187336_4 DnaJ molecular chaperone homology domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001318 280.0
CMS3_k127_1187336_5 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002036 266.0
CMS3_k127_1187336_6 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001017 263.0
CMS3_k127_1187336_7 - - - - 0.000000000000000000000000000000000000000000000000000003695 190.0
CMS3_k127_1187336_8 - - - - 0.00000000000000000000000000000000000000000000000000000859 191.0
CMS3_k127_1187336_9 Thiamine-binding protein - - - 0.0000000000000000000000000000000000000000000000002192 177.0
CMS3_k127_1230573_0 Belongs to the peptidase S8 family K14647 - - 0.0 1036.0
CMS3_k127_1230573_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.631e-319 981.0
CMS3_k127_1230573_10 helix_turn_helix ASNC type K03718 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004355 272.0
CMS3_k127_1230573_11 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003155 273.0
CMS3_k127_1230573_12 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000002825 182.0
CMS3_k127_1230573_13 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000002852 178.0
CMS3_k127_1230573_14 ribosomal protein K02912 - - 0.0000000000000000000000000000000000000001515 155.0
CMS3_k127_1230573_15 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000000000000001463 143.0
CMS3_k127_1230573_16 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000000000000000009176 109.0
CMS3_k127_1230573_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 470.0
CMS3_k127_1230573_3 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 431.0
CMS3_k127_1230573_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 349.0
CMS3_k127_1230573_5 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 331.0
CMS3_k127_1230573_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 307.0
CMS3_k127_1230573_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 284.0
CMS3_k127_1230573_8 Binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009496 276.0
CMS3_k127_1230573_9 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006615 275.0
CMS3_k127_1259568_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K18604 - 2.1.3.15,6.4.1.2,6.4.1.3 0.0 1023.0
CMS3_k127_1259568_1 Carbamoyl-phosphate synthase L chain K18603 - 6.4.1.2,6.4.1.3 2.055e-287 886.0
CMS3_k127_1259568_2 ATPase family associated with various cellular activities (AAA) K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 353.0
CMS3_k127_1259568_3 Biotin-requiring enzyme K18605 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 295.0
CMS3_k127_1259568_4 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 285.0
CMS3_k127_1259568_5 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000009365 214.0
CMS3_k127_1259568_6 - - - - 0.00000000000000000000000000000000000000000000000000000000002298 206.0
CMS3_k127_1259568_7 Belongs to the complex I 20 kDa subunit family K00331 - 1.6.5.3 0.00000000000000000000000000000009148 123.0
CMS3_k127_1279686_0 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 497.0
CMS3_k127_1279686_1 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001175 257.0
CMS3_k127_1279686_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000576 212.0
CMS3_k127_1279686_3 response regulator, receiver K03413,K07662,K07667 - - 0.000000000000000000000000000000000000000000000000000000009201 201.0
CMS3_k127_1279686_4 - - - - 0.000000000000000000000000000000000000000000009103 163.0
CMS3_k127_1279686_5 PPIC-type PPIASE domain K07533 - 5.2.1.8 0.00000000000000000000000000000000000000000003073 162.0
CMS3_k127_13198_0 Glycosyl transferase family group 2 - - - 0.0 1140.0
CMS3_k127_13198_1 3-isopropylmalate dehydratase, large subunit K01703 - 4.2.1.33,4.2.1.35 1.999e-300 923.0
CMS3_k127_13198_10 F420-0:Gamma-glutamyl ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 439.0
CMS3_k127_13198_11 PFAM Nucleotidyl transferase K00966,K03430 - 2.6.1.37,2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 411.0
CMS3_k127_13198_12 ERCC4 domain K10848 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 404.0
CMS3_k127_13198_13 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 400.0
CMS3_k127_13198_14 DNA-directed RNA polymerase, alpha subunit 40 kD subunit K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 393.0
CMS3_k127_13198_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 354.0
CMS3_k127_13198_16 3-isopropylmalate dehydratase, small subunit K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 325.0
CMS3_k127_13198_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 319.0
CMS3_k127_13198_18 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 292.0
CMS3_k127_13198_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 278.0
CMS3_k127_13198_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 7.135e-260 803.0
CMS3_k127_13198_20 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001652 264.0
CMS3_k127_13198_21 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000005306 230.0
CMS3_k127_13198_22 - - - - 0.000000000000000000000000000000000000000000000000000000000005076 208.0
CMS3_k127_13198_23 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000000000000000000000000000000000000000000004768 198.0
CMS3_k127_13198_24 - - - - 0.0000000000000000000000000000000000000000000000000000001113 195.0
CMS3_k127_13198_25 Pyruvate ferredoxin flavodoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000001318 187.0
CMS3_k127_13198_26 Ribosomal L37ae protein family K02921 - - 0.0000000000000000000000000000000000003202 140.0
CMS3_k127_13198_27 ribonuclease activity K07060 - - 0.0000000000000000000007014 101.0
CMS3_k127_13198_28 - - - - 0.00000000000000000001738 97.0
CMS3_k127_13198_29 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000007545 85.0
CMS3_k127_13198_3 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 2.152e-203 633.0
CMS3_k127_13198_4 ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 604.0
CMS3_k127_13198_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 580.0
CMS3_k127_13198_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 500.0
CMS3_k127_13198_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 487.0
CMS3_k127_13198_8 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 473.0
CMS3_k127_13198_9 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 444.0
CMS3_k127_133293_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002342 252.0
CMS3_k127_133293_10 - - - - 0.000000000000004435 75.0
CMS3_k127_133293_11 BPTI/Kunitz family of serine protease inhibitors. - - - 0.00000000000004648 83.0
CMS3_k127_133293_12 cellulase activity - - - 0.0000000000001287 83.0
CMS3_k127_133293_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002219 242.0
CMS3_k127_133293_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000503 222.0
CMS3_k127_133293_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000005145 184.0
CMS3_k127_133293_6 - - - - 0.00000000000000000000000005219 107.0
CMS3_k127_133293_7 - - - - 0.000000000000000000000001062 104.0
CMS3_k127_133293_8 metallopeptidase activity - - - 0.000000000000000000000001167 118.0
CMS3_k127_133293_9 - - - - 0.00000000000000002212 81.0
CMS3_k127_1333915_0 COG0784 FOG CheY-like receiver K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000008668 229.0
CMS3_k127_1333915_1 transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000002936 207.0
CMS3_k127_1338354_0 Uncharacterised protein family (UPF0182) K09118 - - 0.0 1724.0
CMS3_k127_1338354_1 Initiation factor K03242 - - 3.69e-231 716.0
CMS3_k127_1338354_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 6.709e-224 696.0
CMS3_k127_1338354_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 526.0
CMS3_k127_1338354_4 glutamine amidotransferase K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 293.0
CMS3_k127_1338354_5 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.00000000000000000000000000000000000000000000000000000000000000000002861 233.0
CMS3_k127_1338354_6 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000002846 205.0
CMS3_k127_1338354_7 - - - - 0.0000000000000000000000000000007518 121.0
CMS3_k127_137115_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 6.523e-287 884.0
CMS3_k127_137115_1 aspartate carbamoyltransferase K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 570.0
CMS3_k127_137115_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 478.0
CMS3_k127_137115_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 384.0
CMS3_k127_137115_4 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 296.0
CMS3_k127_137115_5 ATP synthase subunit C K02110,K02124 - - 0.00000000000000000000000000000000000000000006687 161.0
CMS3_k127_137115_6 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000004579 59.0
CMS3_k127_143886_0 RNase L inhibitor, RLI K06174 - - 0.0 1111.0
CMS3_k127_144394_0 cation diffusion facilitator family transporter - - - 6.801e-246 764.0
CMS3_k127_144394_1 divalent heavy-metal cations transporter - - - 5.897e-217 677.0
CMS3_k127_144394_2 PFAM Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 445.0
CMS3_k127_144394_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000004005 218.0
CMS3_k127_144394_4 - - - - 0.00000000000000000000007321 98.0
CMS3_k127_148061_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1405.0
CMS3_k127_148061_1 Heat shock 70 kDa protein K04043 - - 0.0 1086.0
CMS3_k127_148061_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 288.0
CMS3_k127_148061_11 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000000000000000000000000000000002896 173.0
CMS3_k127_148061_12 - - - - 0.00000000000000000000000001138 109.0
CMS3_k127_148061_13 ABC-2 type transporter K01992 - - 0.0000000000000000000000002189 105.0
CMS3_k127_148061_14 - - - - 0.000000000005091 65.0
CMS3_k127_148061_15 - - - - 0.000000000005658 66.0
CMS3_k127_148061_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 3.5e-323 997.0
CMS3_k127_148061_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 7.235e-245 759.0
CMS3_k127_148061_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - 3.48e-232 720.0
CMS3_k127_148061_5 DnaJ central domain K03686 - - 1.518e-209 653.0
CMS3_k127_148061_6 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 550.0
CMS3_k127_148061_7 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 472.0
CMS3_k127_148061_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 432.0
CMS3_k127_148061_9 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) K05967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 305.0
CMS3_k127_152394_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 6.128e-212 662.0
CMS3_k127_152394_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000664 265.0
CMS3_k127_152394_2 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.0000000000000000000000006725 103.0
CMS3_k127_173685_0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 2.975e-240 751.0
CMS3_k127_173685_1 TIGRFAM precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 456.0
CMS3_k127_173685_2 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 414.0
CMS3_k127_173685_3 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 407.0
CMS3_k127_173685_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 312.0
CMS3_k127_173685_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005639 274.0
CMS3_k127_1756796_0 Succinyl-CoA ligase like flavodoxin domain K18593 - - 0.0 1119.0
CMS3_k127_1756796_1 Vinylacetyl-CoA Delta-isomerase K14534 - 4.2.1.120,5.3.3.3 6.19e-321 983.0
CMS3_k127_1756796_2 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000003625 153.0
CMS3_k127_1756796_3 Lysyl oxidase - - - 0.00000000000000000000000000000000004148 145.0
CMS3_k127_1779781_0 PFAM Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 3.317e-203 636.0
CMS3_k127_1779781_1 chromosome segregation and condensation protein ScpA K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 413.0
CMS3_k127_1779781_2 segregation and condensation protein K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 334.0
CMS3_k127_1781359_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) - - - 2.146e-268 827.0
CMS3_k127_1781359_1 Transcription elongation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 321.0
CMS3_k127_1781359_2 - - - - 0.0000000000000000000000000000000000000000000000000000002147 204.0
CMS3_k127_1781359_3 - - - - 0.000000000000000000000000000000000000000000008262 163.0
CMS3_k127_1781359_4 - - - - 0.0000000000000000000000000000000000000002253 152.0
CMS3_k127_1781359_5 Cupredoxin-like domain - - - 0.000000000000002902 75.0
CMS3_k127_180313_0 MGS-like domain K01955 - 6.3.5.5 0.0 1953.0
CMS3_k127_180313_1 AAA domain (Cdc48 subfamily) - - - 1.258e-244 757.0
CMS3_k127_180313_10 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 322.0
CMS3_k127_180313_11 conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 289.0
CMS3_k127_180313_13 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008489 271.0
CMS3_k127_180313_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000839 268.0
CMS3_k127_180313_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000964 233.0
CMS3_k127_180313_16 ATP synthase (F/14-kDa) subunit K02122 - - 0.0000000000000000000000000000000000000000000000000000000000008392 211.0
CMS3_k127_180313_17 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000004945 194.0
CMS3_k127_180313_18 - - - - 0.000000000000000000000000000000000000000000000000000005321 190.0
CMS3_k127_180313_19 - - - - 0.000000000000000000000000000000000000000000000001094 175.0
CMS3_k127_180313_2 TIGRFAM 2-methylcitrate synthase citrate synthase II K01647 - 2.3.3.1 2.274e-240 744.0
CMS3_k127_180313_20 - - - - 0.0000000000000000000000000000000000000001261 153.0
CMS3_k127_180313_21 - - - - 0.0000000000000000000000000000000000007915 141.0
CMS3_k127_180313_22 - - - - 0.0000000000000000000000000000000001637 133.0
CMS3_k127_180313_3 Sugar-specific transcriptional regulator TrmB - - - 3.714e-227 706.0
CMS3_k127_180313_4 carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 2.457e-216 674.0
CMS3_k127_180313_5 DHHA1 domain K07463 - - 1.73e-202 633.0
CMS3_k127_180313_6 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 5.908e-200 625.0
CMS3_k127_180313_7 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 531.0
CMS3_k127_180313_8 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 442.0
CMS3_k127_180313_9 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 340.0
CMS3_k127_1816529_0 Aldo/keto reductase family - - - 3.12e-202 633.0
CMS3_k127_1816529_1 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 539.0
CMS3_k127_1816529_2 UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 345.0
CMS3_k127_1816529_3 Transcriptional regulator K07108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009513 273.0
CMS3_k127_1816529_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000001336 219.0
CMS3_k127_1816529_5 Alba K03622 - - 0.0000000000000000000000000000000000000000005403 158.0
CMS3_k127_1816529_6 YHS domain - - - 0.00000000000000000000000003651 107.0
CMS3_k127_192211_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.504e-236 734.0
CMS3_k127_192211_1 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 507.0
CMS3_k127_192211_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 389.0
CMS3_k127_192211_3 Amino acid kinase family K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 292.0
CMS3_k127_192211_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.000000005867 56.0
CMS3_k127_1926464_0 Belongs to the UPF0284 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 507.0
CMS3_k127_1926464_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 402.0
CMS3_k127_1926464_2 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX K17759 - 5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 396.0
CMS3_k127_1926464_3 Translin family K07477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 349.0
CMS3_k127_1947129_0 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 379.0
CMS3_k127_1947129_1 Cupredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008997 250.0
CMS3_k127_1947129_2 Protein of unknown function (DUF1059) - - - 0.000000000000000000007734 92.0
CMS3_k127_1979993_0 fumarate reductase flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.0 1141.0
CMS3_k127_1979993_1 argininosuccinate lyase K01755 - 4.3.2.1 5.891e-264 818.0
CMS3_k127_1979993_10 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 293.0
CMS3_k127_1979993_11 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 280.0
CMS3_k127_1979993_12 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000004025 233.0
CMS3_k127_1979993_13 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001814 224.0
CMS3_k127_1979993_14 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000000000000000000000000000000000000000000000000000000000003883 209.0
CMS3_k127_1979993_15 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000000000000000000000000000000000114 204.0
CMS3_k127_1979993_16 Trm112p-like protein - - - 0.0000000000000000000000000000000000000000000004042 167.0
CMS3_k127_1979993_17 - - - - 0.000000000000000000000000008788 112.0
CMS3_k127_1979993_18 small metal-binding protein - - - 0.000000000002177 68.0
CMS3_k127_1979993_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 587.0
CMS3_k127_1979993_3 Oxidoreductase family, NAD-binding Rossmann fold K18855 - 1.1.1.374 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 566.0
CMS3_k127_1979993_4 oxidoreductase FAD NAD(P)-binding K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 565.0
CMS3_k127_1979993_5 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 527.0
CMS3_k127_1979993_6 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 486.0
CMS3_k127_1979993_7 glycosyl transferase family K01001 - 2.7.8.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 464.0
CMS3_k127_1979993_8 Nicotinamide-nucleotide adenylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 338.0
CMS3_k127_1979993_9 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 307.0
CMS3_k127_201648_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 448.0
CMS3_k127_201648_1 Archaeal TRASH domain - - - 0.00000000000000000000000000000000000000000000000000001036 193.0
CMS3_k127_2050655_0 CBS domain K03498 - - 1.439e-304 942.0
CMS3_k127_2050655_1 Domain of unknown function (DUF1297) K06863 - 6.3.4.23 6.265e-223 692.0
CMS3_k127_2050655_10 - - - - 0.0000000000000000000000000000000000000000002486 159.0
CMS3_k127_2050655_11 - - - - 0.000000000000000000000000000000000000000002985 158.0
CMS3_k127_2050655_12 - - - - 0.00000000000000000000000000000001711 126.0
CMS3_k127_2050655_13 - - - - 0.0000000000000000000000000000005625 126.0
CMS3_k127_2050655_14 mttA/Hcf106 family K03116 - - 0.000000000000001599 77.0
CMS3_k127_2050655_17 - - - - 0.0000000000006473 69.0
CMS3_k127_2050655_2 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 533.0
CMS3_k127_2050655_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 471.0
CMS3_k127_2050655_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 345.0
CMS3_k127_2050655_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 314.0
CMS3_k127_2050655_6 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001661 263.0
CMS3_k127_2050655_7 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000003225 207.0
CMS3_k127_2050655_8 - - - - 0.00000000000000000000000000000000000000000000000000000000005659 207.0
CMS3_k127_2050655_9 - - - - 0.00000000000000000000000000000000000000000001627 162.0
CMS3_k127_2060034_0 Peptidase family M1 domain K01256,K13722 - 3.4.11.2 0.0 1283.0
CMS3_k127_2060034_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 3.11e-212 660.0
CMS3_k127_2060034_2 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 574.0
CMS3_k127_2060034_3 elongation factor Tu - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 556.0
CMS3_k127_2060034_4 Protein of unknown function (DUF726) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 425.0
CMS3_k127_2060034_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 360.0
CMS3_k127_2060034_6 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 348.0
CMS3_k127_2060034_7 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 293.0
CMS3_k127_2060034_8 - - - - 0.0000000000000000000000000000000000000000000000001901 178.0
CMS3_k127_209200_0 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 1.389e-222 691.0
CMS3_k127_209200_1 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 486.0
CMS3_k127_2134272_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 450.0
CMS3_k127_2134272_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 430.0
CMS3_k127_2134272_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000001675 240.0
CMS3_k127_2134272_3 membrane protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001744 235.0
CMS3_k127_2134272_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002188 233.0
CMS3_k127_2139259_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0 1047.0
CMS3_k127_2139259_1 PFAM Aldehyde dehydrogenase K00135,K18601 - 1.2.1.16,1.2.1.20,1.2.1.79 1.117e-282 871.0
CMS3_k127_2139259_10 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 496.0
CMS3_k127_2139259_11 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 487.0
CMS3_k127_2139259_12 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 475.0
CMS3_k127_2139259_13 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 410.0
CMS3_k127_2139259_14 TPR repeat K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 384.0
CMS3_k127_2139259_15 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 366.0
CMS3_k127_2139259_16 Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity K08096 - 3.5.4.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 360.0
CMS3_k127_2139259_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 365.0
CMS3_k127_2139259_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 348.0
CMS3_k127_2139259_19 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 342.0
CMS3_k127_2139259_2 UbiD family decarboxylase - - - 1.272e-262 811.0
CMS3_k127_2139259_20 Hemerythrin HHE cation binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 322.0
CMS3_k127_2139259_21 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 316.0
CMS3_k127_2139259_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 312.0
CMS3_k127_2139259_23 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 294.0
CMS3_k127_2139259_24 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 289.0
CMS3_k127_2139259_25 transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 287.0
CMS3_k127_2139259_26 Patch-forming domain C2 of tRNA-guanine transglycosylase K07398 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003501 270.0
CMS3_k127_2139259_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009535 267.0
CMS3_k127_2139259_28 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001204 262.0
CMS3_k127_2139259_29 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002529 248.0
CMS3_k127_2139259_3 PFAM Alcohol dehydrogenase GroES-like domain - - - 1.188e-228 709.0
CMS3_k127_2139259_30 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000001406 234.0
CMS3_k127_2139259_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001897 233.0
CMS3_k127_2139259_32 Lrp/AsnC ligand binding domain K03718 - - 0.000000000000000000000000000000000000000000000000000000000000000001564 229.0
CMS3_k127_2139259_33 response regulator, receiver K03413 - - 0.000000000000000000000000000000000000000000000000000000000001462 210.0
CMS3_k127_2139259_34 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000000000000000000000000000000000000005057 199.0
CMS3_k127_2139259_35 Binds to the 23S rRNA K02929 - - 0.000000000000000000000000000000000000000000000000001736 183.0
CMS3_k127_2139259_36 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.00000000000000000000000000000000000000000000000001834 180.0
CMS3_k127_2139259_37 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000003917 185.0
CMS3_k127_2139259_38 H subunit K02107 - - 0.000000000000000000000000000000000000000000000007222 173.0
CMS3_k127_2139259_39 Belongs to the PDCD5 family K06875 - - 0.0000000000000000000000000000000000000000000000322 170.0
CMS3_k127_2139259_4 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 3.979e-217 676.0
CMS3_k127_2139259_40 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000001696 161.0
CMS3_k127_2139259_41 - - - - 0.000000000000000000000000000000000003495 138.0
CMS3_k127_2139259_42 - - - - 0.00000000000000000000000000000000003482 136.0
CMS3_k127_2139259_43 TCP-1/cpn60 chaperonin family K22447 - - 0.0000000000000000000000000000000001961 132.0
CMS3_k127_2139259_44 - - - - 0.00000000000000000000000007909 110.0
CMS3_k127_2139259_45 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000008555 107.0
CMS3_k127_2139259_46 - - - - 0.0000000000000000000005473 96.0
CMS3_k127_2139259_47 PFAM ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000002939 65.0
CMS3_k127_2139259_48 - - - - 0.000008339 49.0
CMS3_k127_2139259_5 Amidohydrolase family - - - 6.87e-214 668.0
CMS3_k127_2139259_6 Phosphate uptake regulator - - - 3.312e-201 629.0
CMS3_k127_2139259_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 5.716e-199 623.0
CMS3_k127_2139259_8 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 587.0
CMS3_k127_2139259_9 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 503.0
CMS3_k127_2152838_0 ABC1 family - - - 8.113e-293 903.0
CMS3_k127_2152838_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 1.746e-231 721.0
CMS3_k127_2152838_10 - - - - 0.00000000000000000000000000000000000000000000000000000005331 197.0
CMS3_k127_2152838_11 - - - - 0.000000000000000000000000000000000000000006647 156.0
CMS3_k127_2152838_12 - - - - 0.00000000000000000000000000000005643 126.0
CMS3_k127_2152838_14 ABC-type antimicrobial peptide transport system, ATPase component K02003,K09810 - - 0.00000000000000007088 79.0
CMS3_k127_2152838_2 extracellular matrix structural constituent - - - 5.558e-229 714.0
CMS3_k127_2152838_3 ATP synthase (C/AC39) subunit K02119 - - 1.804e-204 638.0
CMS3_k127_2152838_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008627 419.0
CMS3_k127_2152838_5 CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 391.0
CMS3_k127_2152838_6 thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 342.0
CMS3_k127_2152838_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002058 274.0
CMS3_k127_2152838_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004908 229.0
CMS3_k127_2152838_9 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000000000000000000000000000000001292 222.0
CMS3_k127_2198451_0 Radical SAM K06937 - - 0.0 1150.0
CMS3_k127_2198451_1 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 1.023e-273 859.0
CMS3_k127_2198451_2 FtsX-like permease family K09808 - - 7.361e-222 691.0
CMS3_k127_2198451_3 extracellular matrix structural constituent - - - 2.454e-205 646.0
CMS3_k127_2198451_4 Archaeal transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 442.0
CMS3_k127_2198451_5 ABC-type antimicrobial peptide transport system, ATPase component K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 347.0
CMS3_k127_2198451_6 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001385 278.0
CMS3_k127_2318082_0 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis K07332 - - 3.025e-316 973.0
CMS3_k127_2318082_1 - - - - 5.313e-200 627.0
CMS3_k127_2318082_2 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 332.0
CMS3_k127_2318082_3 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.00000000000000000000000000000003389 126.0
CMS3_k127_2439836_0 TIGRFAM excinuclease ABC, C subunit K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 471.0
CMS3_k127_2439836_1 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 420.0
CMS3_k127_2509059_0 Succinyl-CoA ligase like flavodoxin domain K18594 - - 0.0 1295.0
CMS3_k127_2509059_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 7.211e-262 808.0
CMS3_k127_2509059_2 Belongs to the enoyl-CoA hydratase isomerase family K15019 - 4.2.1.116 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 490.0
CMS3_k127_2509059_3 glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 394.0
CMS3_k127_2509059_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 366.0
CMS3_k127_2509059_5 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001938 242.0
CMS3_k127_2509059_6 regulatory protein, arsR - - - 0.00000000000000000000000000000000000000000000000000000000000000008981 222.0
CMS3_k127_2509059_7 transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000006936 199.0
CMS3_k127_2509059_8 Toprim domain - - - 0.0000000000000000000000000000000000000000000000000000005694 194.0
CMS3_k127_2534459_0 peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 304.0
CMS3_k127_2534459_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003834 260.0
CMS3_k127_2534459_2 - - - - 0.00000000000000000000000000000000000006257 142.0
CMS3_k127_2534459_3 - - - - 0.00000000000000000000004649 103.0
CMS3_k127_2884745_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0 1014.0
CMS3_k127_2884745_1 LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 524.0
CMS3_k127_2884745_2 - - - - 0.00000000000000000000000000000000000000000000002177 171.0
CMS3_k127_2888880_0 - - - - 0.0 1568.0
CMS3_k127_2888880_1 - - - - 2.698e-213 672.0
CMS3_k127_2888880_2 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 5.03e-202 629.0
CMS3_k127_2888880_3 Protein of unknown function (DUF1698) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 362.0
CMS3_k127_2888880_4 geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009871 293.0
CMS3_k127_2888880_5 - - - - 0.0000000000000000477 81.0
CMS3_k127_2888880_7 - - - - 0.00073 44.0
CMS3_k127_2892286_0 Belongs to the MCM family K10726 - - 0.0 1144.0
CMS3_k127_2892286_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 4.871e-300 922.0
CMS3_k127_2892286_10 COG1525 Micrococcal nuclease (thermonuclease) homologs K01174 - 3.1.31.1 0.0000000000000000000000000000000000000000000000000000000000000000000003211 245.0
CMS3_k127_2892286_11 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000000000000006578 165.0
CMS3_k127_2892286_12 - - - - 0.00000000000000000000000000000000000005027 147.0
CMS3_k127_2892286_15 small metal-binding protein - - - 0.0000000000000000026 85.0
CMS3_k127_2892286_16 sister chromatid segregation - - - 0.000000000000000004284 83.0
CMS3_k127_2892286_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 1.428e-250 776.0
CMS3_k127_2892286_3 Glucose sorbosone - - - 2.078e-215 674.0
CMS3_k127_2892286_4 Replication factor C K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 576.0
CMS3_k127_2892286_5 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 571.0
CMS3_k127_2892286_6 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 382.0
CMS3_k127_2892286_7 PFAM 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 354.0
CMS3_k127_2892286_8 PFAM 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 343.0
CMS3_k127_2892286_9 HD domain K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 301.0
CMS3_k127_290394_0 Multicopper oxidase K00368 - 1.7.2.1 2.639e-286 882.0
CMS3_k127_290394_1 Fumarase C C-terminus K01744 - 4.3.1.1 5.521e-269 831.0
CMS3_k127_290394_2 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 5.311e-253 785.0
CMS3_k127_290394_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 564.0
CMS3_k127_290394_4 Tubulin/FtsZ family, GTPase domain K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 536.0
CMS3_k127_290394_5 cytochrome-c peroxidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 400.0
CMS3_k127_290394_6 Methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 382.0
CMS3_k127_290394_7 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 292.0
CMS3_k127_290394_8 Belongs to the ribosomal protein L31e family K02910 - - 0.000000000000000000000000000000000000000000000000000009984 192.0
CMS3_k127_290394_9 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.00000000000000000000004864 98.0
CMS3_k127_2931735_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0 998.0
CMS3_k127_2931735_1 Histone acetyltransferase K07739 - 2.3.1.48 7.4e-323 990.0
CMS3_k127_2931735_10 Protein of unknown function (DUF1512) - - - 9.333e-198 620.0
CMS3_k127_2931735_11 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 554.0
CMS3_k127_2931735_12 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 493.0
CMS3_k127_2931735_13 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 442.0
CMS3_k127_2931735_14 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 368.0
CMS3_k127_2931735_15 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 337.0
CMS3_k127_2931735_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 307.0
CMS3_k127_2931735_17 PFAM Ferritin, Dps family protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 287.0
CMS3_k127_2931735_18 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002127 248.0
CMS3_k127_2931735_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006006 230.0
CMS3_k127_2931735_2 Radical SAM K11781 - 2.5.1.77 4.224e-245 760.0
CMS3_k127_2931735_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000001814 213.0
CMS3_k127_2931735_21 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000007639 212.0
CMS3_k127_2931735_22 Putative tRNA binding domain K06878 - - 0.00000000000000000000000000000000000000000000000000000000001632 207.0
CMS3_k127_2931735_23 Lamin Tail Domain - - - 0.0000000000000000000000000000000000000000000000000000000117 199.0
CMS3_k127_2931735_24 - - - - 0.0000000000000000000000000000000000000000000000000008372 184.0
CMS3_k127_2931735_26 - - - - 0.00000000000000000000000000000000000000000001072 164.0
CMS3_k127_2931735_28 - - - - 0.0000000000000000000000000000002089 123.0
CMS3_k127_2931735_29 - - - - 0.00000000000000000000000000002164 118.0
CMS3_k127_2931735_3 Sodium hydrogen exchanger - - - 8.415e-221 689.0
CMS3_k127_2931735_30 - - - - 0.00000000000000000000000000023 115.0
CMS3_k127_2931735_31 - - - - 0.0000000000000000000005744 96.0
CMS3_k127_2931735_32 metalloendopeptidase activity - - - 0.00000000000000000001659 93.0
CMS3_k127_2931735_35 - - - - 0.0009165 42.0
CMS3_k127_2931735_4 COG1914 Mn2 and Fe2 transporters of the NRAMP family - - - 9.691e-221 691.0
CMS3_k127_2931735_5 modulator of DNA gyrase K03592 - - 2.86e-216 678.0
CMS3_k127_2931735_6 Radical SAM K11780 - 2.5.1.77 2.701e-215 672.0
CMS3_k127_2931735_7 PFAM Glycosyl transferase family 2 K07011,K11936 - - 1.113e-206 647.0
CMS3_k127_2931735_8 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 3.672e-204 640.0
CMS3_k127_2931735_9 Trypsin-like serine protease with C-terminal PDZ domain - - - 1.013e-201 632.0
CMS3_k127_2932628_0 SMC proteins Flexible Hinge Domain K03529 - - 1.449e-281 872.0
CMS3_k127_2932628_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 388.0
CMS3_k127_2932628_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 325.0
CMS3_k127_2948687_0 Protein of unknown function, DUF255 K06888 - - 0.0 1223.0
CMS3_k127_2948687_1 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 608.0
CMS3_k127_2948687_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003354 273.0
CMS3_k127_2948687_3 - - - - 0.000000000000000000000000000000000000000000000000000002212 192.0
CMS3_k127_2948687_4 - - - - 0.0000000000000000000000000000000000000000000001844 169.0
CMS3_k127_2948687_5 - - - - 0.0000000000000000000000000000002124 127.0
CMS3_k127_2948687_6 - - - - 0.0000000000000007663 79.0
CMS3_k127_2948687_7 - - - - 0.0000000000000009478 77.0
CMS3_k127_2976987_0 SNF2 family N-terminal domain - - - 0.0 1097.0
CMS3_k127_2976987_1 - - - - 2.302e-226 707.0
CMS3_k127_2976987_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 571.0
CMS3_k127_2976987_3 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 407.0
CMS3_k127_2976987_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 374.0
CMS3_k127_2976987_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008007 276.0
CMS3_k127_2976987_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000005221 214.0
CMS3_k127_2976987_7 - - - - 0.000000000000000000000000000000000000000000001501 165.0
CMS3_k127_2976987_8 metallopeptidase activity - - - 0.00000000000000000000000000000000000000001004 157.0
CMS3_k127_2976987_9 - - - - 0.00000000000000000000000001838 108.0
CMS3_k127_2997359_0 Peptidase family M3 K08602 - - 0.0 1054.0
CMS3_k127_2997359_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 604.0
CMS3_k127_2997359_2 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 372.0
CMS3_k127_2997359_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 361.0
CMS3_k127_2997359_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009054 269.0
CMS3_k127_2997359_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007131 235.0
CMS3_k127_2997359_6 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000000000000000006026 177.0
CMS3_k127_2997359_7 - - - - 0.00000000000000000000001607 99.0
CMS3_k127_2997359_8 - - - - 0.00000000000001256 75.0
CMS3_k127_2999498_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 292.0
CMS3_k127_2999498_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 285.0
CMS3_k127_2999498_2 copper ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003682 254.0
CMS3_k127_3062887_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 428.0
CMS3_k127_3062887_1 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 319.0
CMS3_k127_3063987_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.461e-284 876.0
CMS3_k127_3063987_1 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 2.613e-267 825.0
CMS3_k127_3063987_10 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001944 243.0
CMS3_k127_3063987_11 - - - - 0.000000000000000000000000000000000000000000000000000000000001269 214.0
CMS3_k127_3063987_12 - - - - 0.000000000000000000000000000000000000000000000000001614 183.0
CMS3_k127_3063987_13 Haem utilisation ChuX/HutX - - - 0.000000000000000000000000000000000000000000000000008068 182.0
CMS3_k127_3063987_14 AAA domain K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000009149 152.0
CMS3_k127_3063987_2 FAD dependent oxidoreductase K15736 - - 3.943e-231 720.0
CMS3_k127_3063987_3 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 3.434e-207 646.0
CMS3_k127_3063987_4 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 543.0
CMS3_k127_3063987_5 Belongs to the universal ribosomal protein uS5 family K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 449.0
CMS3_k127_3063987_6 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 355.0
CMS3_k127_3063987_7 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 344.0
CMS3_k127_3063987_8 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 292.0
CMS3_k127_3063987_9 ribosomal protein K02907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001135 267.0
CMS3_k127_3070072_0 - - - - 1.188e-247 769.0
CMS3_k127_3070072_1 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 442.0
CMS3_k127_3070072_2 aspartate carbamoyltransferase K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000403 214.0
CMS3_k127_3070072_3 Ribbon-helix-helix protein, copG family K07722 - - 0.00000000000000000000000000000000000000000000001622 170.0
CMS3_k127_307109_0 NOSIC (NUC001) domain K14564 - - 1.841e-232 723.0
CMS3_k127_307109_1 Catalyzes the conversion of dihydroorotate to orotate K00226,K00254,K17723,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.1,1.3.1.14,1.3.5.2,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 562.0
CMS3_k127_307109_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000003164 151.0
CMS3_k127_30754_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 9.676e-196 612.0
CMS3_k127_30754_1 - - - - 0.000000000000000000000000000000000000000000000000000000000002622 209.0
CMS3_k127_3099368_0 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 467.0
CMS3_k127_3099368_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 394.0
CMS3_k127_3099368_2 Queuosine biosynthesis protein QueC K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 377.0
CMS3_k127_3099368_3 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 325.0
CMS3_k127_3099368_4 Conserved hypothetical ATP binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000001122 208.0
CMS3_k127_3099368_5 - - - - 0.000000000000000000000000006271 110.0
CMS3_k127_3099368_6 - - - - 0.0000000000000000000003014 99.0
CMS3_k127_3122950_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 477.0
CMS3_k127_3122950_1 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 466.0
CMS3_k127_3122950_2 DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 366.0
CMS3_k127_3122950_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001013 246.0
CMS3_k127_3122950_4 zinc finger - - - 0.000000000000000000000000000000000000000000000000008068 182.0
CMS3_k127_3122950_5 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000003905 137.0
CMS3_k127_3122950_7 geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000004342 110.0
CMS3_k127_3142480_0 Cobalamin B12-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 511.0
CMS3_k127_3142480_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 507.0
CMS3_k127_3142480_2 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 358.0
CMS3_k127_3142480_3 Cytidylyltransferase-like K02201 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000009425 250.0
CMS3_k127_3142480_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000008711 216.0
CMS3_k127_3142480_5 - - - - 0.000000000000000000000000000000001007 134.0
CMS3_k127_3142480_6 - - - - 0.0000000000000000000000000000005391 126.0
CMS3_k127_3142480_7 Cytochrome C oxidase, subunit II K00376,K02275 - 1.7.2.4,1.9.3.1 0.0000000000000000000000000003858 119.0
CMS3_k127_3142480_8 COGs COG3316 Transposase and inactivated derivatives - - - 0.00000000000008035 75.0
CMS3_k127_3143426_0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 497.0
CMS3_k127_3143426_1 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 460.0
CMS3_k127_3150789_0 Radical SAM - - - 0.0 1189.0
CMS3_k127_3150789_1 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 1.558e-220 687.0
CMS3_k127_3150789_10 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000007325 130.0
CMS3_k127_3150789_11 - - - - 0.000000000000000000000000000004547 119.0
CMS3_k127_3150789_12 Ribosomal protein S30 K02983 - - 0.00000000000000000000000000001105 118.0
CMS3_k127_3150789_13 - - - - 0.000000000000000000000001326 103.0
CMS3_k127_3150789_14 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 0.0000000000000000008201 88.0
CMS3_k127_3150789_15 Methyltransferase K02493 - 2.1.1.297 0.0000003198 59.0
CMS3_k127_3150789_2 Radical SAM domain protein K06941 - 2.1.1.192 3.53e-209 652.0
CMS3_k127_3150789_3 Isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.629e-196 615.0
CMS3_k127_3150789_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 515.0
CMS3_k127_3150789_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 483.0
CMS3_k127_3150789_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 388.0
CMS3_k127_3150789_7 Protein of unknown function (DUF655) K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 336.0
CMS3_k127_3150789_8 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000002373 201.0
CMS3_k127_3150789_9 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.00000000000000000000000000000000000000000000000000000004108 196.0
CMS3_k127_3154810_0 Sodium hydrogen exchanger K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 433.0
CMS3_k127_3154810_1 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 355.0
CMS3_k127_3154810_2 ribosomal protein K02866 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 322.0
CMS3_k127_3154810_3 COG1061 DNA or RNA helicases of superfamily II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 312.0
CMS3_k127_3154810_4 transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002105 270.0
CMS3_k127_3154810_5 - - - - 0.00000000000000000000000000000000000000000000000000000000007413 207.0
CMS3_k127_3154810_6 COG0784 FOG CheY-like receiver K03413 - - 0.0000000000000000000000000000000000000003109 153.0
CMS3_k127_3154810_7 - - - - 0.0000000000000000425 83.0
CMS3_k127_3283384_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0 1095.0
CMS3_k127_3283384_1 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008199 238.0
CMS3_k127_3283384_2 acetolactate synthase, small K01653 - 2.2.1.6 0.000000000000005169 74.0
CMS3_k127_3305682_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 4.774e-205 641.0
CMS3_k127_3305682_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 555.0
CMS3_k127_3305682_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006197 245.0
CMS3_k127_3305682_3 - - - - 0.0000000000000000000000000000000000022 138.0
CMS3_k127_3305682_4 Alba K03622 - - 0.0000000000000000000000000000006039 125.0
CMS3_k127_3342739_0 PFAM tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 4.966e-256 794.0
CMS3_k127_3342739_1 GTPase of unknown function C-terminal K06942 - - 5.095e-237 736.0
CMS3_k127_3342739_10 - - - - 0.0000000000000000000000000000000001643 135.0
CMS3_k127_3342739_2 Archaeal Nre, N-terminal - - - 5.056e-216 674.0
CMS3_k127_3342739_3 biotin-(Acetyl-CoA-carboxylase) ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 556.0
CMS3_k127_3342739_4 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 442.0
CMS3_k127_3342739_5 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005981 277.0
CMS3_k127_3342739_6 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008808 241.0
CMS3_k127_3342739_7 - - - - 0.000000000000000000000000000000000000000000000000000000000006875 209.0
CMS3_k127_3342739_8 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000113 169.0
CMS3_k127_3342739_9 - - - - 0.000000000000000000000000000000000000000001789 156.0
CMS3_k127_3400033_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 2325.0
CMS3_k127_3400033_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1752.0
CMS3_k127_3400033_10 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009228 259.0
CMS3_k127_3400033_11 - - - - 0.000000000000000000000000000000000000000000000000000000003042 200.0
CMS3_k127_3400033_12 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.0000000000000000000000000000000000000000000000000002302 186.0
CMS3_k127_3400033_13 Like-Sm ribonucleoprotein core K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000005394 125.0
CMS3_k127_3400033_15 sister chromatid segregation - - - 0.000000000000000000001739 106.0
CMS3_k127_3400033_16 BsuBI/PstI restriction endonuclease C-terminus K07317 - 2.1.1.72 0.000000000000000004928 85.0
CMS3_k127_3400033_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1615.0
CMS3_k127_3400033_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 9.295e-212 659.0
CMS3_k127_3400033_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 604.0
CMS3_k127_3400033_5 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 578.0
CMS3_k127_3400033_6 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 472.0
CMS3_k127_3400033_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 376.0
CMS3_k127_3400033_8 Participates in transcription termination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 291.0
CMS3_k127_3400033_9 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 287.0
CMS3_k127_346370_0 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 569.0
CMS3_k127_346370_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 496.0
CMS3_k127_346370_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002669 255.0
CMS3_k127_346370_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001713 252.0
CMS3_k127_346370_4 Tetrahydromethanopterin S-methyltransferase, subunit A K00577 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000002765 249.0
CMS3_k127_346370_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002068 240.0
CMS3_k127_346370_6 dUTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000005094 224.0
CMS3_k127_346370_7 - - - - 0.0000000000000000721 82.0
CMS3_k127_346370_8 IMP dehydrogenase activity - - - 0.00004046 47.0
CMS3_k127_3589047_0 AAA ATPase domain - - - 0.0 1309.0
CMS3_k127_3589047_1 - - - - 1.31e-319 991.0
CMS3_k127_3589047_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 526.0
CMS3_k127_3589047_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 317.0
CMS3_k127_3589047_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000478 273.0
CMS3_k127_3589047_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004051 226.0
CMS3_k127_3589047_6 - - - - 0.000000000000000000000000000000000000000000000001149 175.0
CMS3_k127_3589047_7 - - - - 0.000000000000000000000005885 100.0
CMS3_k127_361526_0 ribosomal protein L3 K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 594.0
CMS3_k127_361526_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 536.0
CMS3_k127_361526_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 282.0
CMS3_k127_361526_11 conserved protein (DUF2299) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006864 265.0
CMS3_k127_361526_12 Domain of unknown function (DUF4352) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002058 250.0
CMS3_k127_361526_13 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008098 239.0
CMS3_k127_361526_14 Domain of unknown function (DUF371) K09738 - - 0.000000000000000000000000000000000000000000000000000000000000000000038 233.0
CMS3_k127_361526_15 Located at the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000000000000000000000000002345 223.0
CMS3_k127_361526_16 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000000000000000000000000000005628 216.0
CMS3_k127_361526_17 - - - - 0.000000000000000000000000000000000000000000000000000000000006963 208.0
CMS3_k127_361526_18 - - - - 0.000000000000000000000000000000000000000000000000005065 181.0
CMS3_k127_361526_19 - - - - 0.0000000000000000000000000000000000000000000002141 167.0
CMS3_k127_361526_2 Putative RNA methyltransferase K09142 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 469.0
CMS3_k127_361526_20 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.000000000000000000000000000000000000000000002283 167.0
CMS3_k127_361526_21 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.00000000000000000000000000000000000000003937 152.0
CMS3_k127_361526_22 ribosomal protein S14 K02954 - - 0.0000000000000000000000000000000002241 132.0
CMS3_k127_361526_23 - - - - 0.000000000000000000000000000000008282 129.0
CMS3_k127_361526_24 conserved protein implicated in secretion - - - 0.00000000000000000000000000001202 118.0
CMS3_k127_361526_25 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000000000001017 113.0
CMS3_k127_361526_27 - - - - 0.000001791 50.0
CMS3_k127_361526_3 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 467.0
CMS3_k127_361526_4 Ribosomal protein L4 K02930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 466.0
CMS3_k127_361526_5 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 428.0
CMS3_k127_361526_6 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 422.0
CMS3_k127_361526_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 320.0
CMS3_k127_361526_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 302.0
CMS3_k127_361526_9 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 286.0
CMS3_k127_3639688_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 9.857e-284 874.0
CMS3_k127_3639688_1 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 553.0
CMS3_k127_3639688_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000003174 142.0
CMS3_k127_3767246_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 514.0
CMS3_k127_381112_0 Aminotransferase class-V - - - 1.673e-230 715.0
CMS3_k127_381112_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 584.0
CMS3_k127_381112_2 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 417.0
CMS3_k127_381112_3 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 421.0
CMS3_k127_381112_4 Cytidylyltransferase-like K00952 - 2.7.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000002886 241.0
CMS3_k127_381112_5 - - - - 0.0000000000000000000000000000000000000000000000000000001505 198.0
CMS3_k127_381112_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00001077 47.0
CMS3_k127_381112_7 Domain of unknown function (DUF4149) - - - 0.0001577 50.0
CMS3_k127_3820777_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 525.0
CMS3_k127_3820777_1 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 350.0
CMS3_k127_3823352_0 Lamin Tail Domain - - - 0.0 1465.0
CMS3_k127_3823352_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0 1357.0
CMS3_k127_3823352_2 Predicted membrane protein (DUF2070) K08979 - - 3.047e-311 960.0
CMS3_k127_3823352_3 Ribosome biogenesis protein, C-terminal K09140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 305.0
CMS3_k127_3823352_4 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000000000000000000003356 199.0
CMS3_k127_3823352_5 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.000000000000000000000000000000000000000203 151.0
CMS3_k127_3823352_6 Sec61beta family - - - 0.0000000000000000000001471 97.0
CMS3_k127_3823352_7 - - - - 0.000000000000001175 85.0
CMS3_k127_3826822_0 Diphthamide biosynthesis K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 481.0
CMS3_k127_3826822_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 338.0
CMS3_k127_3826822_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000007569 225.0
CMS3_k127_3868849_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1088.0
CMS3_k127_3868849_1 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 596.0
CMS3_k127_3874386_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 2.542e-250 775.0
CMS3_k127_3874386_1 Heme copper-type cytochrome quinol K02274 - 1.9.3.1 2.835e-229 710.0
CMS3_k127_3874386_10 Pyridoxamine 5'-phosphate oxidase - - - 0.00003641 51.0
CMS3_k127_3874386_2 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 418.0
CMS3_k127_3874386_3 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 389.0
CMS3_k127_3874386_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 343.0
CMS3_k127_3874386_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 323.0
CMS3_k127_3874386_6 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 291.0
CMS3_k127_3874386_7 - - - - 0.0000000000000000000000000000000000000000000000001766 177.0
CMS3_k127_3874386_8 - - - - 0.0000000000000000000000000000000000000001654 150.0
CMS3_k127_3874386_9 - - - - 0.000000000000000000000000000000000000002021 147.0
CMS3_k127_3899783_0 Formyl transferase K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 516.0
CMS3_k127_3899783_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 482.0
CMS3_k127_3899783_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 430.0
CMS3_k127_3899783_3 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 432.0
CMS3_k127_3899783_4 Ribose 5-phosphate isomerase K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 406.0
CMS3_k127_3899783_5 Belongs to the phosphohexose mutase family K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 300.0
CMS3_k127_3899783_6 snRNP Sm proteins K04796 - - 0.00000000000000000000000000000000000000649 145.0
CMS3_k127_3899783_7 Binds to the 23S rRNA K02922 - - 0.0000000000000000000000000000003087 122.0
CMS3_k127_3899783_8 Amidohydrolase family K01464 - 3.5.2.2 0.0000000000000000000000000000008412 121.0
CMS3_k127_3903045_0 modulator of DNA gyrase K03568 - - 1.885e-243 758.0
CMS3_k127_3903045_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 541.0
CMS3_k127_3903045_10 - - - - 0.0000000000000000000000000000001037 124.0
CMS3_k127_3903045_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 379.0
CMS3_k127_3903045_3 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 351.0
CMS3_k127_3903045_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 282.0
CMS3_k127_3903045_5 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001246 277.0
CMS3_k127_3903045_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002843 239.0
CMS3_k127_3903045_7 Winged helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000003863 180.0
CMS3_k127_3903045_8 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000002438 155.0
CMS3_k127_3903045_9 - - - - 0.000000000000000000000000000000000003077 139.0
CMS3_k127_3930109_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 3.378e-205 642.0
CMS3_k127_3930109_1 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 588.0
CMS3_k127_3930109_2 RNA methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 427.0
CMS3_k127_3930109_3 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 374.0
CMS3_k127_3930109_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 315.0
CMS3_k127_3930109_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 311.0
CMS3_k127_3930109_6 - - - - 0.000000000000000000000000000000000000000000000003023 175.0
CMS3_k127_3930109_7 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000000000000000000000004036 162.0
CMS3_k127_3930109_8 - - - - 0.00000000000000000000000000000000000000001191 153.0
CMS3_k127_3940160_0 Carbon-nitrogen hydrolase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 486.0
CMS3_k127_3940160_1 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 371.0
CMS3_k127_3940160_2 - - - - 0.00000000000000000000000000000000000000000000000000000000002432 207.0
CMS3_k127_3940160_3 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000000000000002772 120.0
CMS3_k127_3945759_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.279e-312 960.0
CMS3_k127_3945759_1 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 325.0
CMS3_k127_3945759_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004111 246.0
CMS3_k127_3945759_3 acetolactate synthase, small K01653 - 2.2.1.6 0.0000000000000002528 78.0
CMS3_k127_3969754_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 299.0
CMS3_k127_3969754_1 - - - - 0.0000000000000000000000000000000000000000004465 158.0
CMS3_k127_3969754_2 - - - - 0.00000000000000000000000000000000000000000206 158.0
CMS3_k127_3969754_3 - - - - 0.0000000000000000000000000000000000000007817 148.0
CMS3_k127_3992534_0 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 485.0
CMS3_k127_3992534_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 420.0
CMS3_k127_3992534_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 344.0
CMS3_k127_3992534_3 - - - - 0.0000000000000000000000000000000000000000000000000005936 186.0
CMS3_k127_4219990_0 AIPR protein - - - 0.0 1098.0
CMS3_k127_4219990_1 Belongs to the RtcB family K14415 - 6.5.1.3 1.009e-300 924.0
CMS3_k127_4219990_10 THUMP domain K06963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001246 277.0
CMS3_k127_4219990_11 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000000000000000000000000000000000000000009555 209.0
CMS3_k127_4219990_12 Bacterial Fe(2+) trafficking - - - 0.000000000000000000000000000000000000000000000000000003427 190.0
CMS3_k127_4219990_13 - - - - 0.00000000000000000000000000000000000000000000000000005501 189.0
CMS3_k127_4219990_14 - - - - 0.00000000000000000000000000000000000000000000000002712 179.0
CMS3_k127_4219990_15 Winged helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000427 173.0
CMS3_k127_4219990_16 Winged helix-turn-helix - - - 0.00000000000000000000000000000000000000000000008905 169.0
CMS3_k127_4219990_17 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000003501 175.0
CMS3_k127_4219990_18 - - - - 0.000000000000000000000000000000000000000005184 156.0
CMS3_k127_4219990_19 - - - - 0.000000000000000000000000000000000003475 137.0
CMS3_k127_4219990_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - - 1.184e-238 741.0
CMS3_k127_4219990_20 transcription factor (CBF NF-Y) - - - 0.00000000000000000000000000000000003204 135.0
CMS3_k127_4219990_21 ribosomal protein K02962 - - 0.0000000000000000000000000000002523 127.0
CMS3_k127_4219990_22 - - - - 0.0000000000000000000000007886 105.0
CMS3_k127_4219990_23 - - - - 0.00000000000000000000001983 100.0
CMS3_k127_4219990_24 - - - - 0.0000000000000005078 79.0
CMS3_k127_4219990_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 5.354e-207 645.0
CMS3_k127_4219990_4 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 444.0
CMS3_k127_4219990_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 377.0
CMS3_k127_4219990_6 Kinase binding protein CGI-121 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009751 380.0
CMS3_k127_4219990_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 377.0
CMS3_k127_4219990_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 280.0
CMS3_k127_4219990_9 Located on the platform of the 30S subunit K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000627 280.0
CMS3_k127_4238298_0 Cysteine synthase K12339 - 2.5.1.47 5.148e-209 650.0
CMS3_k127_4238298_1 Chlorophyllase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000009949 197.0
CMS3_k127_4238298_2 - - - - 0.00000000000000000000000000000000000000000001589 163.0
CMS3_k127_4238298_3 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000006528 151.0
CMS3_k127_449621_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 475.0
CMS3_k127_449621_1 NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 460.0
CMS3_k127_449621_2 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000145 231.0
CMS3_k127_449621_3 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000002231 125.0
CMS3_k127_4779088_0 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 571.0
CMS3_k127_4779088_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003416 245.0
CMS3_k127_4779088_2 Succinyl-CoA ligase like flavodoxin domain K18593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008992 241.0
CMS3_k127_4779088_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001386 235.0
CMS3_k127_4779088_4 Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000000000000000000000000000000000001948 194.0
CMS3_k127_4779088_5 - - - - 0.000000000000000000000000000000000000000000005204 164.0
CMS3_k127_4779088_6 - - - - 0.0000000000000000000000000000000000000002687 149.0
CMS3_k127_4790013_0 component I K01657 - 4.1.3.27 8.71e-263 814.0
CMS3_k127_4790013_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 4.606e-248 767.0
CMS3_k127_4790013_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 584.0
CMS3_k127_4790013_3 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 384.0
CMS3_k127_4790013_4 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000001581 264.0
CMS3_k127_4790013_5 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.00000000000000000000000000000000000000000000000000000000008895 207.0
CMS3_k127_4790013_6 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000003891 197.0
CMS3_k127_4791961_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 456.0
CMS3_k127_4791961_1 - - - - 0.0000000000000000000000000000003981 123.0
CMS3_k127_4791961_2 Zn-dependent hydrolases of the beta-lactamase fold K14952 - - 0.00000000000000006098 83.0
CMS3_k127_4791961_3 glycosyl transferase, family 39 - - - 0.000001811 60.0
CMS3_k127_4797999_0 copper ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 606.0
CMS3_k127_4797999_1 Adenylate guanylate cyclase with integral membrane sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 511.0
CMS3_k127_4797999_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000264 172.0
CMS3_k127_4852359_0 synthetase (class II) K01880 - 6.1.1.14 6.206e-302 927.0
CMS3_k127_4852359_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 1.02e-207 647.0
CMS3_k127_4852359_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 543.0
CMS3_k127_4852359_3 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 303.0
CMS3_k127_4853266_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 3.749e-242 749.0
CMS3_k127_4853266_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 4.446e-201 630.0
CMS3_k127_4853266_2 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 503.0
CMS3_k127_4853266_3 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 471.0
CMS3_k127_4853266_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 412.0
CMS3_k127_4853266_5 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 391.0
CMS3_k127_4866807_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 7.04e-261 805.0
CMS3_k127_4866807_1 Phosphoglycerate kinase K00927 - 2.7.2.3 1.804e-241 749.0
CMS3_k127_4866807_2 FeS assembly protein SufD K09014,K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 379.0
CMS3_k127_4866807_3 SUF system FeS assembly protein K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 280.0
CMS3_k127_4866807_4 of nitrite reductase and ring-hydroxylating K05710 - - 0.00000000000000000000000000000000000000000000000000000000107 201.0
CMS3_k127_4866807_5 - - - - 0.00000000000000000000000000000001373 130.0
CMS3_k127_487435_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 404.0
CMS3_k127_487435_1 - - - - 0.00000000000000000000000000002055 119.0
CMS3_k127_487435_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000001438 87.0
CMS3_k127_487435_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000001667 73.0
CMS3_k127_4891087_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.224e-317 973.0
CMS3_k127_4891087_1 TCP-1/cpn60 chaperonin family K22447 - - 1.412e-305 939.0
CMS3_k127_4891087_2 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 520.0
CMS3_k127_4891087_3 Pterin binding enzyme K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 458.0
CMS3_k127_4891087_4 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 374.0
CMS3_k127_4891087_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 317.0
CMS3_k127_4891087_6 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000009514 199.0
CMS3_k127_4891087_7 - - - - 0.0000000000000000000000000000000000000000000000000004275 186.0
CMS3_k127_4891087_8 Domain of unknown function (DUF2024) - - - 0.00000000000000000000000000000000000000000000006846 169.0
CMS3_k127_4891887_0 Radical SAM K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 549.0
CMS3_k127_4891887_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 398.0
CMS3_k127_4891887_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000006191 158.0
CMS3_k127_4940608_0 - - - - 0.000000000000000000000001635 106.0
CMS3_k127_4940608_1 peptidyl-tyrosine sulfation - - - 0.000000000115 73.0
CMS3_k127_4941542_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1050.0
CMS3_k127_4941542_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 9.262e-264 814.0
CMS3_k127_4941542_2 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 387.0
CMS3_k127_4941542_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 364.0
CMS3_k127_4941542_4 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 290.0
CMS3_k127_4941542_5 HIT domain K02503 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001483 246.0
CMS3_k127_4941542_6 HELICc2 - - - 0.000000000000000000000000000000000000000000000005974 171.0
CMS3_k127_4941542_8 - - - - 0.000000000000000000000000000000003877 128.0
CMS3_k127_4951979_0 - - - - 8.683e-271 840.0
CMS3_k127_4951979_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 5.694e-261 808.0
CMS3_k127_4951979_10 Dual specificity phosphatase, catalytic domain K14165 - 3.1.3.16,3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 331.0
CMS3_k127_4951979_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008376 256.0
CMS3_k127_4951979_12 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000000000000000000000000000000000000002276 200.0
CMS3_k127_4951979_13 RNA polymerase Rpb3/Rpb11 dimerisation domain K03056 - 2.7.7.6 0.0000000000000000000000000000000000000000000000004448 176.0
CMS3_k127_4951979_14 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000000000001042 151.0
CMS3_k127_4951979_15 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000003024 149.0
CMS3_k127_4951979_16 zinc finger - - - 0.000000000000000000000000000000694 122.0
CMS3_k127_4951979_17 - - - - 0.0000000000000000000000000000008202 121.0
CMS3_k127_4951979_18 - - - - 0.00000000000000000000001353 100.0
CMS3_k127_4951979_19 - - - - 0.000000000000000006205 83.0
CMS3_k127_4951979_2 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 3.959e-219 683.0
CMS3_k127_4951979_3 Tyrosine--tRNA ligase K01866 - 6.1.1.1 1.65e-211 661.0
CMS3_k127_4951979_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K05934 - 2.1.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 512.0
CMS3_k127_4951979_5 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 481.0
CMS3_k127_4951979_6 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 443.0
CMS3_k127_4951979_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 359.0
CMS3_k127_4951979_8 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 349.0
CMS3_k127_4951979_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 333.0
CMS3_k127_4960571_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1037.0
CMS3_k127_4960571_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 6.378e-194 607.0
CMS3_k127_4960571_2 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 487.0
CMS3_k127_4960571_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 329.0
CMS3_k127_4960571_4 ribosomal protein K02976 - - 0.0000000000000000000000000000000000000000000000000002043 185.0
CMS3_k127_4960571_5 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000001823 96.0
CMS3_k127_4963702_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 4.796e-286 880.0
CMS3_k127_4963702_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.358e-272 839.0
CMS3_k127_4963702_10 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 560.0
CMS3_k127_4963702_11 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 509.0
CMS3_k127_4963702_12 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 482.0
CMS3_k127_4963702_13 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 436.0
CMS3_k127_4963702_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 428.0
CMS3_k127_4963702_15 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 405.0
CMS3_k127_4963702_16 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 375.0
CMS3_k127_4963702_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 353.0
CMS3_k127_4963702_18 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 323.0
CMS3_k127_4963702_19 Functions by promoting the formation of the first peptide bond K03263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001454 272.0
CMS3_k127_4963702_2 phosphoglycerate mutase K15635 - 5.4.2.12 9.745e-252 780.0
CMS3_k127_4963702_20 UbiD family decarboxylase K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002775 265.0
CMS3_k127_4963702_21 Acetyltransferase (GNAT) domain K00621 - 2.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001746 260.0
CMS3_k127_4963702_22 GHMP kinases N terminal domain K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000002556 248.0
CMS3_k127_4963702_23 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000004761 232.0
CMS3_k127_4963702_24 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000000000000000000000000000000000000000009089 219.0
CMS3_k127_4963702_25 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000000000000000000000000000000000000000000000008464 194.0
CMS3_k127_4963702_26 - - - - 0.000000000000000000000000000000000000000000000000000003094 194.0
CMS3_k127_4963702_27 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000000000000000000000008099 130.0
CMS3_k127_4963702_28 Cold shock protein domain K03704 - - 0.000000000000000000000000000000001467 130.0
CMS3_k127_4963702_29 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000004504 125.0
CMS3_k127_4963702_3 Chorismate mutase type II K00812 - 2.6.1.1 1.048e-248 772.0
CMS3_k127_4963702_31 NUDIX domain - - - 0.000000000000000000008143 96.0
CMS3_k127_4963702_32 Domain of unknown function (DUF309) - - - 0.000000001146 66.0
CMS3_k127_4963702_4 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) - - - 1.488e-231 719.0
CMS3_k127_4963702_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 2.192e-231 721.0
CMS3_k127_4963702_6 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 6.779e-222 689.0
CMS3_k127_4963702_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 8.112e-215 669.0
CMS3_k127_4963702_8 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 1.274e-211 659.0
CMS3_k127_4963702_9 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 608.0
CMS3_k127_4977640_0 PFAM Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000004776 239.0
CMS3_k127_4977640_1 domain protein - - - 0.0000000000000000000000000000000002731 145.0
CMS3_k127_5002509_0 Peptidase family M50 - - - 2.06e-220 687.0
CMS3_k127_5002509_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 602.0
CMS3_k127_5002509_2 PP-loop family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 566.0
CMS3_k127_5002509_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001419 253.0
CMS3_k127_5002509_4 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000004098 179.0
CMS3_k127_5002509_5 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000000000000001152 164.0
CMS3_k127_5003195_0 Amino acid kinase family K00928 - 2.7.2.4 6.649e-234 731.0
CMS3_k127_5003195_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 576.0
CMS3_k127_5003195_2 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 472.0
CMS3_k127_5003195_3 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008686 272.0
CMS3_k127_5003195_4 - - - - 0.00000000000000000000000000001596 117.0
CMS3_k127_5003195_5 - - - - 0.00000000000000000000003226 100.0
CMS3_k127_5021998_0 acid phosphatase activity - - - 0.0 1019.0
CMS3_k127_5021998_1 Amidohydrolase family K01464 - 3.5.2.2 4.455e-277 854.0
CMS3_k127_5021998_2 Zinc finger domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 410.0
CMS3_k127_5021998_3 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 399.0
CMS3_k127_5021998_4 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 355.0
CMS3_k127_5021998_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 326.0
CMS3_k127_5021998_6 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001994 278.0
CMS3_k127_5021998_7 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001023 231.0
CMS3_k127_5021998_8 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000000000000000003176 223.0
CMS3_k127_5021998_9 - - - - 0.000000000000000000000002956 106.0
CMS3_k127_5023036_0 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 600.0
CMS3_k127_5023036_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 529.0
CMS3_k127_5023036_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 513.0
CMS3_k127_5023036_3 phosphoribosylglycinamide formyltransferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 340.0
CMS3_k127_5023036_4 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000007639 192.0
CMS3_k127_5023036_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000004332 185.0
CMS3_k127_5023036_6 Antibiotic biosynthesis monooxygenase K21481 - 1.14.99.57 0.00000000000000000000000000000000000000000000246 166.0
CMS3_k127_5023036_7 - - - - 0.00000000000000000002799 89.0
CMS3_k127_5023869_0 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 2.57e-227 706.0
CMS3_k127_5023869_1 - - - - 7.575e-205 651.0
CMS3_k127_5043732_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 591.0
CMS3_k127_5043732_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 475.0
CMS3_k127_5043732_2 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 394.0
CMS3_k127_5043732_3 Lysine exporter protein LysE YggA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 294.0
CMS3_k127_5043732_4 Alba K03622 - - 0.000000000000000000000000000000000000000000000000007544 184.0
CMS3_k127_5062040_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0 1062.0
CMS3_k127_5062040_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 492.0
CMS3_k127_5062040_2 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 327.0
CMS3_k127_5062040_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004457 250.0
CMS3_k127_5067842_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1807.0
CMS3_k127_5067842_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.594e-286 891.0
CMS3_k127_5067842_2 TIGRFAM excinuclease ABC, C subunit K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 401.0
CMS3_k127_5071527_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 2.538e-261 809.0
CMS3_k127_5071527_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 9.812e-253 783.0
CMS3_k127_5071527_2 - - - - 0.000000000000000000000000000000000000002798 148.0
CMS3_k127_5086239_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0 1073.0
CMS3_k127_5086239_1 Belongs to the phosphohexose mutase family K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 584.0
CMS3_k127_5086239_2 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002775 265.0
CMS3_k127_5086239_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000004555 258.0
CMS3_k127_5086239_4 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001435 242.0
CMS3_k127_5086239_5 Binds to the 23S rRNA K02896 - - 0.0000000000000000000000000000000001083 134.0
CMS3_k127_5086239_6 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000000005579 116.0
CMS3_k127_5086239_8 acid phosphatase activity - - - 0.0000000000000002821 80.0
CMS3_k127_5088933_0 HELICc2 - - - 6.427e-254 790.0
CMS3_k127_5088933_1 Peptidase M10A and M12B matrixin and adamalysin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 421.0
CMS3_k127_5088933_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001691 242.0
CMS3_k127_5088933_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001149 235.0
CMS3_k127_5088933_4 - - - - 0.0000000000000000000000000000000000000000000000001523 177.0
CMS3_k127_5088933_5 - - - - 0.0000000000000000000000000000000000000000002002 159.0
CMS3_k127_5088933_7 - - - - 0.00000000000000000000000001479 110.0
CMS3_k127_5088933_8 - - - - 0.000000000000000000000002314 104.0
CMS3_k127_5094362_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 555.0
CMS3_k127_5094362_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 287.0
CMS3_k127_5094362_2 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000009443 133.0
CMS3_k127_5095393_0 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 556.0
CMS3_k127_5095393_1 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 401.0
CMS3_k127_5095393_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005382 271.0
CMS3_k127_5095393_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000008281 211.0
CMS3_k127_5095393_4 - - - - 0.000000000000000000000000000000000000000000000000000777 185.0
CMS3_k127_5095393_5 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000002822 149.0
CMS3_k127_5095393_7 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000004716 54.0
CMS3_k127_5095393_8 Major facilitator superfamily - - - 0.000000063 60.0
CMS3_k127_5120429_0 AAA domain K03546 - - 0.0 1006.0
CMS3_k127_5120429_1 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 408.0
CMS3_k127_5120429_2 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.00000000000000000000000000000000001151 136.0
CMS3_k127_5131143_0 Domain of unknown function DUF87 K06915 - - 1.264e-261 809.0
CMS3_k127_5131143_1 NurA - - - 0.000000000000000000000000000000000000000000000000000000002168 200.0
CMS3_k127_5147973_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1001.0
CMS3_k127_5147973_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 445.0
CMS3_k127_5147973_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 412.0
CMS3_k127_5147973_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 285.0
CMS3_k127_5147973_4 - - - - 0.000000000000000000000000000000000000000000000000000000001328 203.0
CMS3_k127_5147973_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000003754 159.0
CMS3_k127_5147973_6 mttA/Hcf106 family K03116 - - 0.000000000000000006769 85.0
CMS3_k127_5224855_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001448 278.0
CMS3_k127_5224855_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001491 262.0
CMS3_k127_5224855_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000006315 220.0
CMS3_k127_5224855_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000001626 219.0
CMS3_k127_5224855_4 - - - - 0.0000000000000000000000000000000000000000000000000000009172 198.0
CMS3_k127_5224855_5 COG4618 ABC-type protease lipase transport system, ATPase and permease components - - - 0.000000000000000000000000000000000000000004253 157.0
CMS3_k127_5224855_7 transcriptional regulators - - - 0.000000000000000000000000000000000007585 138.0
CMS3_k127_5224855_8 CBS domain - - - 0.000000000000000001257 87.0
CMS3_k127_5243308_0 Mechanosensitive ion channel K05802 - - 1.329e-300 930.0
CMS3_k127_5243308_1 TIGRFAM lysine 2,3-aminomutase YodO family protein - - - 3.126e-295 906.0
CMS3_k127_5243308_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 1.316e-254 789.0
CMS3_k127_5243308_3 DnaJ molecular chaperone homology domain - - - 1.506e-211 661.0
CMS3_k127_5243308_4 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 487.0
CMS3_k127_5243308_5 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 323.0
CMS3_k127_5243308_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 308.0
CMS3_k127_5243308_7 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000009235 192.0
CMS3_k127_5243308_8 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000009298 190.0
CMS3_k127_5264994_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 585.0
CMS3_k127_5264994_1 A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 317.0
CMS3_k127_5264994_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006407 263.0
CMS3_k127_5264994_3 - - - - 0.0000000000000000000000000000000000000000000000000002 187.0
CMS3_k127_5264994_4 - - - - 0.00000000000000000000000000000000000000000000001665 171.0
CMS3_k127_5264994_5 RNA methylase - - - 0.000000000000000002773 85.0
CMS3_k127_5264994_6 - - - - 0.0000000000000003363 80.0
CMS3_k127_5300908_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005922 226.0
CMS3_k127_5300908_1 - - - - 0.00000000000000000000000000000000000000000000000000003039 190.0
CMS3_k127_5300908_2 COG0607 Rhodanese-related sulfurtransferase K03406,K21028 - 2.8.1.11 0.00000000000000000000000000000000000000000000000000004415 187.0
CMS3_k127_5300908_3 - - - - 0.0000000000000000000000000000000007982 133.0
CMS3_k127_5300908_4 - - - - 0.00000001164 57.0
CMS3_k127_5367_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.0 1134.0
CMS3_k127_5367_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 8.67e-314 965.0
CMS3_k127_5367_10 PUA domain K07575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 289.0
CMS3_k127_5367_11 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 280.0
CMS3_k127_5367_12 DoxX family K15977,K16937 - 1.8.5.2 0.00000000000000000000000000000000000000000000000000000000000000001017 226.0
CMS3_k127_5367_13 - - - - 0.0000000000000000000000000000000000000000000000000001086 186.0
CMS3_k127_5367_15 - - - - 0.000000000000000000000000000000000000006697 148.0
CMS3_k127_5367_16 - - - - 0.00000000000000000000000000000008519 126.0
CMS3_k127_5367_17 - - - - 0.00000839 48.0
CMS3_k127_5367_18 Predicted membrane protein (DUF2061) - - - 0.0002323 46.0
CMS3_k127_5367_2 Peptidase dimerisation domain - - - 1.609e-267 826.0
CMS3_k127_5367_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 1.304e-202 633.0
CMS3_k127_5367_4 homoserine dehydrogenase K00003 - 1.1.1.3 6.908e-202 631.0
CMS3_k127_5367_5 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 518.0
CMS3_k127_5367_6 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 511.0
CMS3_k127_5367_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 445.0
CMS3_k127_5367_8 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 375.0
CMS3_k127_5367_9 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 307.0
CMS3_k127_5371950_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 - 2.1.1.215,2.1.1.216 3.034e-208 651.0
CMS3_k127_5371950_1 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 408.0
CMS3_k127_5371950_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 334.0
CMS3_k127_5371950_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 301.0
CMS3_k127_5371950_4 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000001497 213.0
CMS3_k127_5376980_0 Anticodon-binding domain of tRNA K01873 - 6.1.1.9 0.0 1501.0
CMS3_k127_5376980_1 adenylosuccinate lyase K01756 - 4.3.2.2 1.789e-264 817.0
CMS3_k127_5376980_10 protein secretion by the type IV secretion system - - - 0.0000000000000008871 89.0
CMS3_k127_5376980_11 peptidyl-tyrosine sulfation - - - 0.0000000000001737 79.0
CMS3_k127_5376980_2 aconitate hydratase K01681 - 4.2.1.3 2.12e-260 804.0
CMS3_k127_5376980_3 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 600.0
CMS3_k127_5376980_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007622 522.0
CMS3_k127_5376980_5 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 426.0
CMS3_k127_5376980_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 311.0
CMS3_k127_5376980_7 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 299.0
CMS3_k127_5376980_8 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000000004945 172.0
CMS3_k127_5376980_9 - - - - 0.0000000000000000000000000000000000002132 149.0
CMS3_k127_5440525_0 SMC proteins Flexible Hinge Domain K03529 - - 0.0 1158.0
CMS3_k127_5440525_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 9.291e-291 895.0
CMS3_k127_5440525_2 DinB superfamily - - - 5.748e-263 813.0
CMS3_k127_5440525_3 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 557.0
CMS3_k127_5440525_4 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 529.0
CMS3_k127_5440525_5 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 409.0
CMS3_k127_5440525_6 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 368.0
CMS3_k127_5440525_7 Chlorophyllase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000005897 257.0
CMS3_k127_5440525_8 - - - - 0.0000000000000000000000000000000000000000000004671 167.0
CMS3_k127_5554651_0 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 460.0
CMS3_k127_5554651_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 404.0
CMS3_k127_5554651_2 - - - - 0.00000000000000000000000000000000000000000005119 168.0
CMS3_k127_5554651_3 nUDIX hydrolase K01515,K01518,K01814 - 3.6.1.13,3.6.1.17,5.3.1.16 0.000000000000000000000000000000000548 136.0
CMS3_k127_5554651_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000003383 81.0
CMS3_k127_5585070_0 resistance protein K14166 - - 9.943e-293 911.0
CMS3_k127_5686279_0 RNA-metabolising metallo-beta-lactamase K07041 - - 0.0 1262.0
CMS3_k127_5686279_1 FtsX-like permease family K09808 - - 8.1e-222 692.0
CMS3_k127_5686279_10 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 393.0
CMS3_k127_5686279_11 ABC-type antimicrobial peptide transport system, ATPase component K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 362.0
CMS3_k127_5686279_12 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 317.0
CMS3_k127_5686279_13 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 294.0
CMS3_k127_5686279_14 - - - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
CMS3_k127_5686279_15 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000002721 143.0
CMS3_k127_5686279_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 1.75e-211 662.0
CMS3_k127_5686279_3 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 7.406e-211 657.0
CMS3_k127_5686279_4 Thiamine biosynthesis protein (ThiI) - - - 1.481e-197 617.0
CMS3_k127_5686279_5 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 552.0
CMS3_k127_5686279_6 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 531.0
CMS3_k127_5686279_7 AsnC-type helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 503.0
CMS3_k127_5686279_8 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 417.0
CMS3_k127_5686279_9 Pfam:DUF137 K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 417.0
CMS3_k127_5749338_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 301.0
CMS3_k127_5749338_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000232 207.0
CMS3_k127_5749338_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.000000000000000000000000000000000000000000001872 165.0
CMS3_k127_5751052_0 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001623 242.0
CMS3_k127_5751052_1 - - - - 0.00000000000000000000000000000000000000000000000001156 180.0
CMS3_k127_5751052_2 - - - - 0.00000000000000000000000000000000000000002905 154.0
CMS3_k127_5751052_3 - - - - 0.00000000000000000000000000000000000002721 143.0
CMS3_k127_5751052_4 - - - - 0.00000000000000000000000000000000000004559 143.0
CMS3_k127_5751052_5 small metal-binding protein - - - 0.0000000000000000000000000000003057 122.0
CMS3_k127_5751052_6 carbon-nitrogen ligase activity, with glutamine as amido-N-donor - - - 0.0000000003991 60.0
CMS3_k127_57547_0 DEAD DEAH box helicase K06877 - - 0.0 1532.0
CMS3_k127_57547_1 major facilitator superfamily K08153,K08221 - - 1.989e-211 661.0
CMS3_k127_57547_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 511.0
CMS3_k127_57547_3 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 502.0
CMS3_k127_57547_4 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 451.0
CMS3_k127_57547_5 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 389.0
CMS3_k127_57547_6 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000254 194.0
CMS3_k127_57547_7 mttA/Hcf106 family K03116 - - 0.0000000000000000000000000000000000000000000000003107 177.0
CMS3_k127_57547_8 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000001157 172.0
CMS3_k127_5760582_0 Amino acid kinase family K00928 - 2.7.2.4 2.179e-254 789.0
CMS3_k127_5760582_1 Histidine kinase - - - 1.96e-251 788.0
CMS3_k127_5760582_10 - - - - 0.0000000000000000000000000000001682 123.0
CMS3_k127_5760582_11 - - - - 0.00000000000000000000000000001734 118.0
CMS3_k127_5760582_12 ORF D-335-like protein - - - 0.0005401 43.0
CMS3_k127_5760582_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 573.0
CMS3_k127_5760582_3 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 539.0
CMS3_k127_5760582_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 402.0
CMS3_k127_5760582_5 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 312.0
CMS3_k127_5760582_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006091 278.0
CMS3_k127_5760582_7 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004673 250.0
CMS3_k127_5760582_8 COG0784 FOG CheY-like receiver K02485,K02490,K03413 - - 0.00000000000000000000000000000000000000000000000000002191 190.0
CMS3_k127_5760582_9 Blue copper protein - - - 0.00000000000000000000000000000000000000003841 153.0
CMS3_k127_5769832_0 DNA polymerase K02319 - 2.7.7.7 0.0 1581.0
CMS3_k127_5769832_1 Pyruvate phosphate dikinase K01006 - 2.7.9.1 1.774e-198 620.0
CMS3_k127_5769832_2 DEAD DEAH box helicase domain protein K03703,K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 452.0
CMS3_k127_5769832_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 386.0
CMS3_k127_5769832_4 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 346.0
CMS3_k127_5769832_5 Sugar efflux transporter for intercellular exchange K15383 - - 0.0000000000000000000000000000000000000000003504 158.0
CMS3_k127_5774976_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 0.0 1014.0
CMS3_k127_5774976_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 8.236e-321 982.0
CMS3_k127_5774976_10 Belongs to the UPF0201 family K09736 - - 0.00000000000000000000000000000000000000000000000000000008334 198.0
CMS3_k127_5774976_11 - - - - 0.0000000000000000000000000000000000000000000000000007778 183.0
CMS3_k127_5774976_12 TIGRFAM Glutaredoxin-like domain protein - - - 0.000000000000000000000000000000000000000000000001962 174.0
CMS3_k127_5774976_13 Ser thr protein kinase K07176 - - 0.00000000000000000000000000000000000000000000008729 177.0
CMS3_k127_5774976_14 zinc finger - - - 0.00000000000000000000000000000000000000000002589 161.0
CMS3_k127_5774976_15 - - - - 0.00000000000000000000000000000000000000008359 152.0
CMS3_k127_5774976_16 - - - - 0.0000000000000000000000005489 105.0
CMS3_k127_5774976_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 1.964e-233 728.0
CMS3_k127_5774976_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 2.303e-213 666.0
CMS3_k127_5774976_4 cytochrome c biogenesis protein K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 575.0
CMS3_k127_5774976_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 462.0
CMS3_k127_5774976_6 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 325.0
CMS3_k127_5774976_7 protein conserved in archaea K09723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 316.0
CMS3_k127_5774976_8 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 300.0
CMS3_k127_5774976_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007617 273.0
CMS3_k127_5778419_0 Aminotransferase class-V - - - 2.825e-235 729.0
CMS3_k127_5778419_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 1.398e-205 642.0
CMS3_k127_5778419_10 Domain of unknown function (DUF4149) - - - 0.000004971 55.0
CMS3_k127_5778419_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 513.0
CMS3_k127_5778419_3 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 463.0
CMS3_k127_5778419_4 Cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 463.0
CMS3_k127_5778419_5 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 296.0
CMS3_k127_5778419_6 Cytidylyltransferase-like K00952 - 2.7.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 293.0
CMS3_k127_5778419_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 271.0
CMS3_k127_5778419_8 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000007232 125.0
CMS3_k127_5778419_9 - - - - 0.0000000000000003132 78.0
CMS3_k127_5784799_0 Large family of predicted nucleotide-binding domains K06865 - - 0.0 1026.0
CMS3_k127_5784799_1 glycosyl transferase family 2 K00721 - 2.4.1.83 9.519e-211 658.0
CMS3_k127_5784799_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 430.0
CMS3_k127_5784799_3 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 375.0
CMS3_k127_5784799_4 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 297.0
CMS3_k127_5784799_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004639 274.0
CMS3_k127_5784799_6 iron dependent repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000005576 231.0
CMS3_k127_5784799_7 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000001146 234.0
CMS3_k127_5784799_8 - - - - 0.0000000000000000000000000000000000000000000000000000006171 194.0
CMS3_k127_5793770_0 DEAD/H associated K03724 - - 0.0 1605.0
CMS3_k127_5793770_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 3.708e-249 773.0
CMS3_k127_5793770_10 Precorrin-8x methylmutase K06042 - 5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000000003133 203.0
CMS3_k127_5793770_11 snRNP Sm proteins K04796 - - 0.000000000000000000000000000000000000000003209 156.0
CMS3_k127_5793770_12 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000001406 120.0
CMS3_k127_5793770_2 S-adenosylmethionine synthetase K00789 - 2.5.1.6 1.968e-233 724.0
CMS3_k127_5793770_3 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 1.143e-212 663.0
CMS3_k127_5793770_4 Cobalamin synthesis G C-terminus K02189 - 3.7.1.12 6.121e-198 619.0
CMS3_k127_5793770_5 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 482.0
CMS3_k127_5793770_6 Cobalt chelatase (CbiK) K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 471.0
CMS3_k127_5793770_7 RecA RadA K04482,K04483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 372.0
CMS3_k127_5793770_8 ATP corrinoid adenosyltransferase K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 318.0
CMS3_k127_5793770_9 Translation initiation factor 2, alpha subunit K03237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009412 264.0
CMS3_k127_5796578_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 5.044e-231 718.0
CMS3_k127_5796578_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 465.0
CMS3_k127_5796578_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 303.0
CMS3_k127_5796578_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004433 235.0
CMS3_k127_5796578_4 - - - - 0.00000000000000000000000000000000000000000000000000000000001692 207.0
CMS3_k127_5796578_5 AbrB family - - - 0.00000000000000000000001334 100.0
CMS3_k127_5824250_0 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 527.0
CMS3_k127_5824250_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 470.0
CMS3_k127_5824250_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001536 263.0
CMS3_k127_5824250_3 - - - - 0.000000000000000000000000000000000000000000000000000000000001711 211.0
CMS3_k127_5824250_4 - - - - 0.00000000000000000000000000000000000000000000000005621 179.0
CMS3_k127_5831052_0 aconitate hydratase K01681 - 4.2.1.3 5.439e-215 670.0
CMS3_k127_5831052_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 423.0
CMS3_k127_5831052_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 372.0
CMS3_k127_5933071_0 Deoxyhypusine synthase K00809 - 2.5.1.46 1.785e-224 697.0
CMS3_k127_5933071_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 571.0
CMS3_k127_5933071_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001243 280.0
CMS3_k127_5933071_3 low-complexity proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008585 266.0
CMS3_k127_5933071_4 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000000000000000000000000003385 199.0
CMS3_k127_5933071_5 - - - - 0.00000000000000000000000000000000000000000000004174 171.0
CMS3_k127_5933071_6 - - - - 0.00000000000000000000000000000001985 126.0
CMS3_k127_6000978_0 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 421.0
CMS3_k127_6000978_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 332.0
CMS3_k127_6000978_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 293.0
CMS3_k127_6004971_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1292.0
CMS3_k127_6004971_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 384.0
CMS3_k127_6004971_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 290.0
CMS3_k127_6004971_3 - - - - 0.0000000000000006926 77.0
CMS3_k127_6015058_0 TIGRFAM phosphate ABC transporter K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 591.0
CMS3_k127_6015058_1 Sodium hydrogen exchanger K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 571.0
CMS3_k127_6015058_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 404.0
CMS3_k127_6015058_11 PhoU domain K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 373.0
CMS3_k127_6015058_12 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 282.0
CMS3_k127_6015058_13 Phosphate uptake regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006573 286.0
CMS3_k127_6015058_14 NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001795 274.0
CMS3_k127_6015058_15 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000491 258.0
CMS3_k127_6015058_16 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007521 246.0
CMS3_k127_6015058_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000009203 231.0
CMS3_k127_6015058_18 - - - - 0.00000000000000000000000000000000000000000000000000000000003921 207.0
CMS3_k127_6015058_19 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000003028 203.0
CMS3_k127_6015058_2 Nitroreductase K19286 - 1.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 555.0
CMS3_k127_6015058_20 - - - - 0.00000000000000000000000000000000000000000000000001238 181.0
CMS3_k127_6015058_21 RNA secondary structure unwinding - - - 0.0000000000000000000000000000000000000000000000000319 182.0
CMS3_k127_6015058_22 - - - - 0.0000000000000000000000000000000000000000000002867 168.0
CMS3_k127_6015058_23 - - - - 0.000000000000000000000000000000000000000001658 158.0
CMS3_k127_6015058_24 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000001748 141.0
CMS3_k127_6015058_25 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000003888 134.0
CMS3_k127_6015058_26 - - - - 0.000000000000000000000000004128 110.0
CMS3_k127_6015058_27 - - - - 0.00000000000000000000000002188 113.0
CMS3_k127_6015058_28 - - - - 0.000000000000000000004035 93.0
CMS3_k127_6015058_3 TIGRFAM phosphate ABC transporter K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 518.0
CMS3_k127_6015058_30 - - - - 0.000001775 51.0
CMS3_k127_6015058_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 504.0
CMS3_k127_6015058_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 499.0
CMS3_k127_6015058_6 Cobalamin B12-binding domain protein K16955,K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 491.0
CMS3_k127_6015058_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 481.0
CMS3_k127_6015058_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 477.0
CMS3_k127_6015058_9 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 421.0
CMS3_k127_60398_0 - - - - 0.0 1464.0
CMS3_k127_60398_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 1.547e-306 942.0
CMS3_k127_60398_10 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036222,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000001497 159.0
CMS3_k127_60398_2 GTPase of unknown function C-terminal K06942 - - 7.764e-245 758.0
CMS3_k127_60398_3 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 2.087e-214 668.0
CMS3_k127_60398_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 - 2.3.1.234 1.873e-200 625.0
CMS3_k127_60398_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 428.0
CMS3_k127_60398_6 Mn2 -dependent serine threonine protein kinase K08851 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 368.0
CMS3_k127_60398_7 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 282.0
CMS3_k127_60398_8 - - - - 0.000000000000000000000000000000000000000000000000000000000009345 207.0
CMS3_k127_60398_9 NADH ubiquinone oxidoreductase - - - 0.00000000000000000000000000000000000000000009184 158.0
CMS3_k127_6065745_0 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 527.0
CMS3_k127_6065745_1 PFAM GCN5-related N-acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 364.0
CMS3_k127_6065745_2 - - - - 0.0000000000000000000000000000000000000000000000000000000005725 203.0
CMS3_k127_6065745_3 TrkA-C domain K03455 - - 0.000000000000000000000000000000000000000000000000000000007599 220.0
CMS3_k127_6065745_4 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000009117 141.0
CMS3_k127_6068418_0 DHHA1 domain K07463 - - 2.042e-288 888.0
CMS3_k127_6068418_1 ribosomal protein K02956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000126 278.0
CMS3_k127_6068418_2 - - - - 0.00000000000000000000000000007789 115.0
CMS3_k127_6110080_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 2.172e-305 938.0
CMS3_k127_6110080_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.173e-249 773.0
CMS3_k127_6110080_2 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 385.0
CMS3_k127_6110080_3 RNA binding K07581 - - 0.0000000000000000000000000000000000000000000000000000000000002203 214.0
CMS3_k127_6110080_4 Transcription factor Pcc1 - - - 0.0000000000000000000000000000000000000005986 148.0
CMS3_k127_611801_0 HMGL-like K01649 - 2.3.3.13 3.503e-247 765.0
CMS3_k127_611801_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 7.825e-245 758.0
CMS3_k127_611801_10 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 407.0
CMS3_k127_611801_11 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 366.0
CMS3_k127_611801_12 Cytidylyltransferase-like K00980,K14656 - 2.7.7.2,2.7.7.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 342.0
CMS3_k127_611801_13 DNA primase K02316 - - 0.000000000000000000000000000000000000000000000000000000000006636 208.0
CMS3_k127_611801_14 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000001433 151.0
CMS3_k127_611801_15 lysine biosynthesis protein LysW K05826 - - 0.000000000000000000000000000002154 120.0
CMS3_k127_611801_16 lysine biosynthesis protein LysW K05826 - - 0.0000000000000000000000000001663 114.0
CMS3_k127_611801_17 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00009016 44.0
CMS3_k127_611801_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 5.715e-237 734.0
CMS3_k127_611801_3 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K05831 - - 6.529e-234 724.0
CMS3_k127_611801_4 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 4.012e-225 698.0
CMS3_k127_611801_5 diphthine synthase K20215 - 2.1.1.98 4.951e-198 621.0
CMS3_k127_611801_6 Lysine biosynthesis K05827 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 547.0
CMS3_k127_611801_7 Lysine biosynthesis K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 544.0
CMS3_k127_611801_8 TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 531.0
CMS3_k127_611801_9 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 482.0
CMS3_k127_6222707_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01870 - 6.1.1.5 0.0 2014.0
CMS3_k127_6222707_1 ATP-grasp domain K01903 - 6.2.1.5 1.452e-218 681.0
CMS3_k127_6222707_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 578.0
CMS3_k127_6222707_3 Ferritin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 396.0
CMS3_k127_6222707_4 - - - - 0.000000000000000000000000000000000000000000000000000000000001875 209.0
CMS3_k127_6222707_5 - - - - 0.0000000000000000000000000000000004661 132.0
CMS3_k127_6222707_6 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000000000000000001852 109.0
CMS3_k127_6241291_0 TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 4.028e-226 701.0
CMS3_k127_6241291_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 568.0
CMS3_k127_6241291_11 Zinc-dependent metalloprotease - - - 0.00000000009308 61.0
CMS3_k127_6241291_12 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000001319 53.0
CMS3_k127_6241291_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 417.0
CMS3_k127_6241291_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 288.0
CMS3_k127_6241291_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004449 253.0
CMS3_k127_6241291_5 COG2002 Regulators of stationary sporulation gene expression - - - 0.000000000000000000000000000000000000000000000000000000000000000000001862 237.0
CMS3_k127_6241291_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000008337 234.0
CMS3_k127_6241291_7 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000007101 218.0
CMS3_k127_6241291_8 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.00000000000000000000000000000000000000000000000000000000000007606 218.0
CMS3_k127_6241291_9 phosphoribosyltransferase K07101 - - 0.0000000000000000000000000000000000000000000000000001774 188.0
CMS3_k127_6689608_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0 1127.0
CMS3_k127_6689608_1 Transglutaminase-like superfamily - - - 1.522e-277 861.0
CMS3_k127_6689608_10 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 304.0
CMS3_k127_6689608_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 297.0
CMS3_k127_6689608_12 COG0784 FOG CheY-like receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002928 252.0
CMS3_k127_6689608_14 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001084 243.0
CMS3_k127_6689608_15 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002866 243.0
CMS3_k127_6689608_16 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001948 240.0
CMS3_k127_6689608_17 COG4618 ABC-type protease lipase transport system, ATPase and permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000004184 225.0
CMS3_k127_6689608_18 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001348 223.0
CMS3_k127_6689608_19 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000000000000000000000000000000000000000000000000000000001003 203.0
CMS3_k127_6689608_2 Sodium hydrogen exchanger - - - 7.777e-269 835.0
CMS3_k127_6689608_20 - - - - 0.000000000000000000000000000000000000000000000000001313 184.0
CMS3_k127_6689608_21 CBS domain - - - 0.00000000000000000000000000000000000000000000000005426 180.0
CMS3_k127_6689608_22 - - - - 0.000000000000000000000000000000000000000000005261 165.0
CMS3_k127_6689608_23 - - - - 0.000000000000000000001403 96.0
CMS3_k127_6689608_24 - - - - 0.0000000005304 61.0
CMS3_k127_6689608_3 small GTP-binding protein K06944 - - 1.905e-220 685.0
CMS3_k127_6689608_4 amino acid K03294 - - 5.598e-220 688.0
CMS3_k127_6689608_5 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 521.0
CMS3_k127_6689608_6 CBS domain K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 438.0
CMS3_k127_6689608_7 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 412.0
CMS3_k127_6689608_8 Phosphoglycolate phosphatase K22223 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 395.0
CMS3_k127_6689608_9 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 337.0
CMS3_k127_6704300_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.968e-197 618.0
CMS3_k127_6704300_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 413.0
CMS3_k127_6704300_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000002777 141.0
CMS3_k127_6710698_0 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 569.0
CMS3_k127_6710698_1 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003468 247.0
CMS3_k127_6710698_2 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000004154 220.0
CMS3_k127_6710698_3 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000006619 206.0
CMS3_k127_6710698_4 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000002829 165.0
CMS3_k127_6718069_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 5.637e-308 947.0
CMS3_k127_6718069_1 von Willebrand factor (vWF) type A domain - - - 2.079e-302 930.0
CMS3_k127_6718069_11 - - - - 0.0000000000000000000000000000000000001325 141.0
CMS3_k127_6718069_12 - - - - 0.00000000000000000005008 89.0
CMS3_k127_6718069_2 Dihydrouridine synthase (Dus) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 593.0
CMS3_k127_6718069_3 ATPase family associated with various cellular activities (AAA) K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 481.0
CMS3_k127_6718069_4 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 368.0
CMS3_k127_6718069_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 340.0
CMS3_k127_6718069_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001325 278.0
CMS3_k127_6718069_7 ASCH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007534 267.0
CMS3_k127_6718069_8 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000003267 186.0
CMS3_k127_6718069_9 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000003643 152.0
CMS3_k127_6728592_0 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 529.0
CMS3_k127_6728592_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 481.0
CMS3_k127_6728592_10 conserved protein implicated in secretion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 354.0
CMS3_k127_6728592_11 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 347.0
CMS3_k127_6728592_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002991 235.0
CMS3_k127_6728592_13 - - - - 0.0000000000000000000000000000000000000000000000000000002064 197.0
CMS3_k127_6728592_14 - - - - 0.0000000000000000000000000000000000000000000000001252 177.0
CMS3_k127_6728592_15 Winged helix-turn-helix - - - 0.000000000000000000000000000000000000000000000005452 172.0
CMS3_k127_6728592_17 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000002183 147.0
CMS3_k127_6728592_18 - - - - 0.00000000000000000000000000000003389 126.0
CMS3_k127_6728592_19 - - - - 0.0000000000000000000000000000001108 124.0
CMS3_k127_6728592_2 Inositol monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 477.0
CMS3_k127_6728592_20 - - - - 0.000000000000000000000001711 115.0
CMS3_k127_6728592_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 456.0
CMS3_k127_6728592_4 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 452.0
CMS3_k127_6728592_5 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 443.0
CMS3_k127_6728592_6 Queuosine biosynthesis protein QueC K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 424.0
CMS3_k127_6728592_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 399.0
CMS3_k127_6728592_8 membrane-associated protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 393.0
CMS3_k127_6728592_9 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 353.0
CMS3_k127_6788860_0 Subtilase family - - - 0.0 1401.0
CMS3_k127_6788860_1 - - - - 0.000000000000000000000000000009669 119.0
CMS3_k127_6789443_0 inner membrane component K02034 - - 2.205e-256 794.0
CMS3_k127_6789443_1 inner membrane component K02033 - - 1.689e-206 644.0
CMS3_k127_6789443_10 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000009151 99.0
CMS3_k127_6789443_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 394.0
CMS3_k127_6789443_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 388.0
CMS3_k127_6789443_4 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001111 248.0
CMS3_k127_6789443_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002725 238.0
CMS3_k127_6789443_6 - - - - 0.0000000000000000000000000000000000000000000000000000000006391 202.0
CMS3_k127_6789443_7 Arsenate reductase and related K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000007464 190.0
CMS3_k127_6789443_8 - - - - 0.0000000000000000000000000000000000000000000000000003572 185.0
CMS3_k127_6789443_9 - - - - 0.00000000000000000000000000000000000000000001924 161.0
CMS3_k127_6928936_0 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 369.0
CMS3_k127_6928936_1 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 287.0
CMS3_k127_6928936_2 Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008129 246.0
CMS3_k127_6928936_3 - - - - 0.000000000000000000000000000000001146 133.0
CMS3_k127_69825_0 Hydroxymethylglutaryl-coenzyme A synthase N terminal K01641 - 2.3.3.10 1.308e-291 896.0
CMS3_k127_69825_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 5.176e-236 735.0
CMS3_k127_69825_10 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K07646,K20989 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009813 273.0
CMS3_k127_69825_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006002 269.0
CMS3_k127_69825_12 xylanase chitin deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000005616 171.0
CMS3_k127_69825_13 - - - - 0.0000000000000000002905 99.0
CMS3_k127_69825_14 cheY-homologous receiver domain - - - 0.00000003652 64.0
CMS3_k127_69825_15 - - - - 0.00000007266 65.0
CMS3_k127_69825_2 Transporter associated domain - - - 2.786e-228 711.0
CMS3_k127_69825_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 5.054e-207 644.0
CMS3_k127_69825_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 5.86e-203 634.0
CMS3_k127_69825_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 572.0
CMS3_k127_69825_6 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 437.0
CMS3_k127_69825_7 8-amino-7-oxononanoate synthase K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 411.0
CMS3_k127_69825_8 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 377.0
CMS3_k127_69825_9 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 301.0
CMS3_k127_6986889_0 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1553.0
CMS3_k127_6986889_1 TIGRFAM CRISPR-associated protein Cas4 K03466,K07464,K15342,K19465 - 3.1.12.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 312.0
CMS3_k127_6986889_2 - - - - 0.000000000000000000000000000000000000000000000000000000001206 203.0
CMS3_k127_7022037_0 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 477.0
CMS3_k127_7022037_1 Uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 394.0
CMS3_k127_7022037_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000009916 220.0
CMS3_k127_7022037_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000003564 209.0
CMS3_k127_7044224_0 Beta propeller domain - - - 0.0 1132.0
CMS3_k127_7044224_1 PFAM aminotransferase class-III K01845 - 5.4.3.8 1.932e-249 772.0
CMS3_k127_7044224_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 446.0
CMS3_k127_7044224_11 Major Intrinsic Protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 394.0
CMS3_k127_7044224_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 388.0
CMS3_k127_7044224_13 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 356.0
CMS3_k127_7044224_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 306.0
CMS3_k127_7044224_15 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002828 264.0
CMS3_k127_7044224_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000006582 235.0
CMS3_k127_7044224_17 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000246 210.0
CMS3_k127_7044224_18 regulatory protein, arsR K03892,K21903 - - 0.00000000000000000000000000000000000000000000000000001629 188.0
CMS3_k127_7044224_19 Nitrogen regulatory protein P-II - - - 0.00000000000000000000000000000000000000000000000001698 181.0
CMS3_k127_7044224_2 NHL repeat containing protein - - - 1.136e-231 726.0
CMS3_k127_7044224_20 Pfam:DUF385 - - - 0.000000000000000000000000000000000000000000000005449 175.0
CMS3_k127_7044224_3 ABC transporter K01990 - - 2.078e-194 608.0
CMS3_k127_7044224_4 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 604.0
CMS3_k127_7044224_5 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 550.0
CMS3_k127_7044224_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 528.0
CMS3_k127_7044224_7 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 486.0
CMS3_k127_7044224_8 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 468.0
CMS3_k127_7044224_9 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 454.0
CMS3_k127_7087254_0 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000001229 180.0
CMS3_k127_7087254_1 Peptidase C13 family - - - 0.000002833 58.0
CMS3_k127_7093294_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 2.987e-211 658.0
CMS3_k127_7093294_1 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 438.0
CMS3_k127_7093294_2 K homology RNA-binding domain K06961 - - 0.000000000000000000000000000000000000000000000000000005325 195.0
CMS3_k127_7169578_0 RNA methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 452.0
CMS3_k127_7169578_1 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002552 269.0
CMS3_k127_7169578_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000004006 212.0
CMS3_k127_7169578_3 Rieske 2Fe-2S K05710 - - 0.00000000000000000000000000000000000000000000000000007353 187.0
CMS3_k127_7169578_4 Belongs to the UPF0147 family K09721 - - 0.00000000000000000000000000000000000000007741 152.0
CMS3_k127_7183632_0 Ribosomal protein L15E K02877 - - 0.0000000000000000000000000000000000000000000000000006442 185.0
CMS3_k127_7183632_1 - - - - 0.00000000000001964 87.0
CMS3_k127_7224003_0 PP-loop family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 583.0
CMS3_k127_7224003_1 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000452 196.0
CMS3_k127_7414446_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 - 3.3.1.1 4.987e-259 799.0
CMS3_k127_7414446_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 476.0
CMS3_k127_7573517_0 - - - - 3.526e-223 694.0
CMS3_k127_7573517_1 ATPase family associated with various cellular activities (AAA) K04800 - - 2.784e-222 691.0
CMS3_k127_7573517_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 8.704e-208 648.0
CMS3_k127_7573517_3 oxidoreductase FAD NAD(P)-binding K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 546.0
CMS3_k127_7573517_4 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 471.0
CMS3_k127_7573517_5 - K03646 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 305.0
CMS3_k127_7573517_6 Protein of unknown function (DUF1059) - - - 0.000000000000000000000000002977 112.0
CMS3_k127_7573517_7 small metal-binding protein - - - 0.000000000000000001626 85.0
CMS3_k127_7625017_0 Mg2 transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 563.0
CMS3_k127_7625017_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 419.0
CMS3_k127_7625017_2 copper ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008724 250.0
CMS3_k127_7625017_3 - - - - 0.000000000000000000000000000000000000000000469 158.0
CMS3_k127_83561_0 LOR SDH bifunctional - - - 5.166e-245 758.0
CMS3_k127_83561_1 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 531.0
CMS3_k127_83561_2 KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 438.0
CMS3_k127_85379_0 Luciferase-like monooxygenase K14728 - - 9.59e-237 733.0
CMS3_k127_85379_1 PFAM Iron-containing alcohol dehydrogenase K18602 - - 7.856e-203 631.0
CMS3_k127_85379_2 Pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 404.0
CMS3_k127_85379_3 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 293.0
CMS3_k127_85379_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001421 240.0
CMS3_k127_85379_5 - - - - 0.000000000000000000000000000006214 120.0
CMS3_k127_97384_0 Required for chromosome condensation and partitioning - - - 2.774e-246 767.0
CMS3_k127_97384_1 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000001977 180.0
CMS3_k127_97384_2 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000054 144.0