Overview

ID MAG00594
Name CSH1_bin.23
Sample SMP0013
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class E2
Order DHVEG-1
Family DHVEG-1
Genus SM1-50
Species
Assembly information
Completeness (%) 90.97
Contamination (%) 1.44
GC content (%) 45.0
N50 (bp) 18,320
Genome size (bp) 1,997,926

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1684

Gene name Description KEGG GOs EC E-value Score Sequence
CSH1_k127_1008074_0 - - - - 0.00000000000000000000000000000000000001701 167.0
CSH1_k127_1008074_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000001296 132.0
CSH1_k127_1008074_2 - - - - 0.0000000000000000007897 100.0
CSH1_k127_1008074_3 - - - - 0.00001073 53.0
CSH1_k127_1008074_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.00007303 52.0
CSH1_k127_1008074_5 - - - - 0.0003713 50.0
CSH1_k127_1030640_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 4.261e-255 803.0
CSH1_k127_1030640_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 474.0
CSH1_k127_1030640_10 Radical SAM - - - 0.0000000000000000000000000000000000000117 154.0
CSH1_k127_1030640_11 phosphorelay signal transduction system - - - 0.00000000000000000000000000000004829 128.0
CSH1_k127_1030640_12 KaiC - - - 0.0000000000000000000000000003986 123.0
CSH1_k127_1030640_13 PFAM periplasmic copper-binding - - - 0.000000000000000000000000001626 132.0
CSH1_k127_1030640_14 cheY-homologous receiver domain K07668 - - 0.00000000000000000000000007575 110.0
CSH1_k127_1030640_15 PFAM periplasmic copper-binding - - - 0.00000000000000000000002485 116.0
CSH1_k127_1030640_16 Phosphoesterase PA-phosphatase - - - 0.000000000000000007317 93.0
CSH1_k127_1030640_17 COG1233 Phytoene dehydrogenase and related proteins K10254 - 4.2.1.53 0.0000000000000002967 92.0
CSH1_k127_1030640_18 PFAM PKD domain containing protein - - - 0.0000000000000003026 89.0
CSH1_k127_1030640_19 Parallel beta-helix - - - 0.00000000005907 76.0
CSH1_k127_1030640_2 PFAM GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 450.0
CSH1_k127_1030640_20 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000003033 70.0
CSH1_k127_1030640_21 Prenyltransferase, UbiA family K09833 GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0018130,GO:0042360,GO:0042362,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 2.5.1.115,2.5.1.116 0.0000000007232 70.0
CSH1_k127_1030640_22 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0002563 52.0
CSH1_k127_1030640_23 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0008467 51.0
CSH1_k127_1030640_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 326.0
CSH1_k127_1030640_4 TatD related DNase K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000002337 239.0
CSH1_k127_1030640_5 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000001322 214.0
CSH1_k127_1030640_6 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.000000000000000000000000000000000000000000000000002443 188.0
CSH1_k127_1030640_7 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000003088 191.0
CSH1_k127_1030640_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000006091 198.0
CSH1_k127_1030640_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000002318 158.0
CSH1_k127_1054370_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 8.972e-260 811.0
CSH1_k127_1054370_1 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 4.973e-256 797.0
CSH1_k127_1054370_2 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 535.0
CSH1_k127_1054370_3 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 459.0
CSH1_k127_1054370_4 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 435.0
CSH1_k127_1054370_5 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000000000003067 246.0
CSH1_k127_1054370_6 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000003981 196.0
CSH1_k127_1054370_7 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000001596 195.0
CSH1_k127_1054370_8 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000002187 168.0
CSH1_k127_1054370_9 Biotin carboxylase C-terminal domain K01968,K13777 - 6.4.1.4,6.4.1.5 0.00000000000002333 81.0
CSH1_k127_1113889_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.833e-298 940.0
CSH1_k127_1113889_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 7.707e-203 654.0
CSH1_k127_1113889_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 510.0
CSH1_k127_1113889_3 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 502.0
CSH1_k127_1113889_4 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 368.0
CSH1_k127_1113889_5 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000006741 248.0
CSH1_k127_1113889_6 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000002721 191.0
CSH1_k127_1113889_7 Belongs to the UPF0178 family - - - 0.000000000000000000000000000000000000000003916 158.0
CSH1_k127_1113889_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.00000000000000000000000000000000000000001027 167.0
CSH1_k127_1113889_9 Papain family cysteine protease - - - 0.0000000000000000001261 102.0
CSH1_k127_1129933_0 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 432.0
CSH1_k127_1129933_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004346 271.0
CSH1_k127_1129933_10 Peptidase family C25 - - - 0.000000004641 68.0
CSH1_k127_1129933_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000003081 212.0
CSH1_k127_1129933_3 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000005855 203.0
CSH1_k127_1129933_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000000000000000000000000000000000000000000000699 196.0
CSH1_k127_1129933_5 CBS domain K03498 - - 0.0000000000000000000000000000000000000000000000001929 194.0
CSH1_k127_1129933_6 K -dependent Na Ca exchanger family protein - - - 0.0000000000000000000000000000000000000000000000002637 188.0
CSH1_k127_1129933_7 - - - - 0.0000000000000000000000000000000001294 134.0
CSH1_k127_1129933_8 Cupin domain - - - 0.0000000000000000000000000000001809 128.0
CSH1_k127_1129933_9 - - - - 0.0000000000005538 75.0
CSH1_k127_1210606_0 Pfam:DUF650 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 473.0
CSH1_k127_1210606_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000002288 221.0
CSH1_k127_1210606_2 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000004704 99.0
CSH1_k127_1210606_3 Belongs to the UPF0235 family K09131 - - 0.000000000000000000005388 96.0
CSH1_k127_1210606_4 TOPRIM - - - 0.000000000000000001251 91.0
CSH1_k127_1269713_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.431e-274 863.0
CSH1_k127_1269713_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000001036 194.0
CSH1_k127_1269713_10 amino acid activation for nonribosomal peptide biosynthetic process K06045 - 4.2.1.129,5.4.99.17 0.00000000000002373 82.0
CSH1_k127_1269713_12 Periplasmic binding protein K02016 - - 0.0000000001567 70.0
CSH1_k127_1269713_13 fosmidomycin resistance protein K08223 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000001439 70.0
CSH1_k127_1269713_2 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000009131 170.0
CSH1_k127_1269713_3 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000005663 153.0
CSH1_k127_1269713_4 4 iron, 4 sulfur cluster binding K00196 - - 0.000000000000000000000000000000001734 134.0
CSH1_k127_1269713_5 GPR1 FUN34 yaaH family protein K07034 - - 0.000000000000000000000000003452 119.0
CSH1_k127_1269713_6 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000002602 111.0
CSH1_k127_1269713_7 serine threonine protein kinase - - - 0.000000000000000000000001338 112.0
CSH1_k127_1269713_8 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.0000000000000005238 85.0
CSH1_k127_1269713_9 - - - - 0.0000000000000007428 84.0
CSH1_k127_1300319_0 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 426.0
CSH1_k127_1304892_0 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000003363 128.0
CSH1_k127_1304892_1 PFAM Circadian clock protein KaiC - - - 0.00000000000000000000000094 113.0
CSH1_k127_1304892_2 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0007563 48.0
CSH1_k127_1326075_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 346.0
CSH1_k127_1326075_1 thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000022 211.0
CSH1_k127_1326075_2 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000003743 191.0
CSH1_k127_1326075_3 NUDIX domain - - - 0.00000000000000000000000000000000002645 139.0
CSH1_k127_1339603_0 cell adhesion involved in biofilm formation K02014,K11031 - - 0.00000000000006099 85.0
CSH1_k127_1385418_0 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 323.0
CSH1_k127_1385418_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 288.0
CSH1_k127_1385418_2 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000000000002496 241.0
CSH1_k127_1385418_3 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.000000000000000000000000000000000000000000000000004706 200.0
CSH1_k127_1385418_4 - - - - 0.0000000000000000000000000000000000000000000008276 167.0
CSH1_k127_1385418_5 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000007753 138.0
CSH1_k127_1385418_6 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000001775 118.0
CSH1_k127_1385418_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000003933 104.0
CSH1_k127_1385418_8 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000005429 67.0
CSH1_k127_1385418_9 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000009143 58.0
CSH1_k127_1487646_0 tRNA synthetases class II (D, K and N) K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 389.0
CSH1_k127_1487646_1 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004265 231.0
CSH1_k127_1487646_2 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000001212 100.0
CSH1_k127_1487646_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000001687 104.0
CSH1_k127_1487646_4 COG2133 Glucose sorbosone dehydrogenases - - - 0.00000003805 66.0
CSH1_k127_1491174_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 356.0
CSH1_k127_1491174_1 by modhmm K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 311.0
CSH1_k127_1491174_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006543 282.0
CSH1_k127_1491174_3 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000003732 226.0
CSH1_k127_1491174_4 Methionine biosynthesis protein MetW - - - 0.000000000000000002817 94.0
CSH1_k127_1491174_5 Methyltransferase type 11 - - - 0.00000002423 58.0
CSH1_k127_1491174_6 COG3420 Nitrous oxidase accessory protein K07218 - - 0.0000001172 58.0
CSH1_k127_1491174_7 distant relative of cell wall-associated - - - 0.0000005113 61.0
CSH1_k127_1491174_8 repeat protein - - - 0.000001666 61.0
CSH1_k127_149938_0 DsrE/DsrF-like family K04085 - - 0.0000000000000000000000000000004061 125.0
CSH1_k127_149938_1 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000001673 91.0
CSH1_k127_1500838_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001151 272.0
CSH1_k127_1500838_1 domain, Protein - - - 0.0007589 51.0
CSH1_k127_1526808_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 3.508e-312 970.0
CSH1_k127_1526808_1 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 383.0
CSH1_k127_1526808_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001804 288.0
CSH1_k127_1526808_3 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004221 267.0
CSH1_k127_1526808_4 Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000003373 221.0
CSH1_k127_1526808_5 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000000000000000000002113 185.0
CSH1_k127_1526808_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000003173 176.0
CSH1_k127_1526808_7 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000001395 78.0
CSH1_k127_1529655_0 PFAM type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 308.0
CSH1_k127_1529655_1 PFAM type II secretion system K07333 - - 0.00000000000000000000000002174 125.0
CSH1_k127_1529655_2 PFAM PKD domain containing protein - - - 0.0000000000002617 80.0
CSH1_k127_1529655_3 PKD domain containing protein - - - 0.00000003399 60.0
CSH1_k127_1606395_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002786 274.0
CSH1_k127_1606395_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000356 229.0
CSH1_k127_1606395_10 response regulator receiver K02657 - - 0.00000033 57.0
CSH1_k127_1606395_2 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000001687 206.0
CSH1_k127_1606395_3 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000000001344 182.0
CSH1_k127_1606395_4 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.000000000000000000000000000000000000000000002903 170.0
CSH1_k127_1606395_5 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000001001 124.0
CSH1_k127_1606395_6 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000005499 139.0
CSH1_k127_1606395_7 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000001856 87.0
CSH1_k127_1606395_8 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K13276 - 3.2.1.4 0.00000009748 66.0
CSH1_k127_1606395_9 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000002471 63.0
CSH1_k127_1682947_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1182.0
CSH1_k127_1682947_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 - 2.7.7.6 0.0 1165.0
CSH1_k127_1682947_2 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 477.0
CSH1_k127_1682947_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 403.0
CSH1_k127_1682947_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000009226 143.0
CSH1_k127_1682947_5 Participates in transcription termination K02600 - - 0.000000000000000000000000000006721 123.0
CSH1_k127_1682947_6 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000002885 103.0
CSH1_k127_1682947_7 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000006143 100.0
CSH1_k127_1682947_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000183 97.0
CSH1_k127_1682947_9 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.0000000000000001436 82.0
CSH1_k127_1743763_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 379.0
CSH1_k127_1743763_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 379.0
CSH1_k127_1743763_2 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 379.0
CSH1_k127_1743763_3 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 311.0
CSH1_k127_1743763_4 Asparaginase, N-terminal K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000003476 232.0
CSH1_k127_1743763_5 Thrombospondin type 3 - - - 0.000000000000000000000008704 114.0
CSH1_k127_1743763_6 PKD domain containing protein - - - 0.00000000000001092 88.0
CSH1_k127_1743763_7 SpoVT / AbrB like domain - - - 0.0000000004272 63.0
CSH1_k127_1743763_8 SprB repeat - - - 0.0004539 52.0
CSH1_k127_1802852_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000002772 193.0
CSH1_k127_1802852_1 outer membrane autotransporter barrel domain - - - 0.00000003648 68.0
CSH1_k127_1802852_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000008412 63.0
CSH1_k127_1802852_3 peptidase inhibitor activity - - - 0.000007971 50.0
CSH1_k127_1802852_4 Transglutaminase-like superfamily - - - 0.00002189 53.0
CSH1_k127_1813145_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000001518 204.0
CSH1_k127_1813145_1 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000113 161.0
CSH1_k127_1813145_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000006724 56.0
CSH1_k127_1813145_3 PFAM PKD domain containing protein - - - 0.000001777 55.0
CSH1_k127_1850965_0 COG1131 ABC-type multidrug transport system ATPase component K16907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 354.0
CSH1_k127_1850965_1 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001977 259.0
CSH1_k127_1850965_10 - - - - 0.0000000000000000000005935 98.0
CSH1_k127_1850965_11 Glycosyl hydrolase family 53 K01224 - 3.2.1.89 0.000000000000001078 89.0
CSH1_k127_1850965_12 - - - - 0.0000000000007919 78.0
CSH1_k127_1850965_13 TfoX N-terminal domain - - - 0.0000000005531 64.0
CSH1_k127_1850965_14 transcriptional regulator, AsnC family K03718 - - 0.000000008694 59.0
CSH1_k127_1850965_15 Acetyltransferase (GNAT) domain - - - 0.0000004555 58.0
CSH1_k127_1850965_16 Lrp/AsnC ligand binding domain - - - 0.0000402 49.0
CSH1_k127_1850965_17 COG1522 Transcriptional regulators - - - 0.00008729 50.0
CSH1_k127_1850965_2 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000003484 228.0
CSH1_k127_1850965_3 Asparaginase, N-terminal K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000002432 225.0
CSH1_k127_1850965_4 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000003767 224.0
CSH1_k127_1850965_5 Flavodoxin - GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000004871 200.0
CSH1_k127_1850965_6 Bacterio-opsin activator HTH K06930,K06988 - 1.5.1.40 0.0000000000000000000000000000000000003327 149.0
CSH1_k127_1850965_7 - K16905,K16906 - - 0.000000000000000000000000000007048 128.0
CSH1_k127_1850965_8 glucosylceramidase activity - - - 0.000000000000000000000000001194 115.0
CSH1_k127_1850965_9 transmembrane transport K01992 - - 0.000000000000000000000000001609 121.0
CSH1_k127_193293_0 Subtilase family - - - 0.0000000000000000003175 103.0
CSH1_k127_193293_1 PFAM NHL repeat containing protein - - - 0.00000000000001195 88.0
CSH1_k127_1975543_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1131.0
CSH1_k127_1975543_1 Cell division protein 48 (CDC48) domain 2 K13525 - - 9.095e-277 875.0
CSH1_k127_1975543_10 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000000000000000000000000000000009769 220.0
CSH1_k127_1975543_11 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000008674 203.0
CSH1_k127_1975543_12 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000000000003683 181.0
CSH1_k127_1975543_13 TIGRFAM geranylgeranyl reductase family - - - 0.0000000000000000000000000000000000001856 147.0
CSH1_k127_1975543_14 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000006499 148.0
CSH1_k127_1975543_15 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.00000000000000000000000000000000004244 137.0
CSH1_k127_1975543_16 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000000002655 130.0
CSH1_k127_1975543_17 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000001446 122.0
CSH1_k127_1975543_18 Peptidase_C39 like family - - - 0.000000000000000000001089 100.0
CSH1_k127_1975543_19 YHS domain - - - 0.000000000000000000002084 93.0
CSH1_k127_1975543_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 3.6.3.54 9.535e-269 851.0
CSH1_k127_1975543_20 PRC-barrel domain - - - 0.000000000000001906 79.0
CSH1_k127_1975543_21 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.0000000000002346 76.0
CSH1_k127_1975543_22 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000002439 60.0
CSH1_k127_1975543_23 - - - - 0.00000002577 61.0
CSH1_k127_1975543_24 - - - - 0.00002442 53.0
CSH1_k127_1975543_25 Bacterial PH domain - - - 0.0004605 52.0
CSH1_k127_1975543_3 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 462.0
CSH1_k127_1975543_4 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 360.0
CSH1_k127_1975543_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 340.0
CSH1_k127_1975543_6 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 306.0
CSH1_k127_1975543_7 threonine synthase activity K01733,K15527 - 2.5.1.76,4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 296.0
CSH1_k127_1975543_8 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001007 254.0
CSH1_k127_1975543_9 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000001247 215.0
CSH1_k127_1985139_0 aconitate hydratase K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 574.0
CSH1_k127_1985139_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 310.0
CSH1_k127_200586_0 Radical SAM domain protein K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 469.0
CSH1_k127_2045449_0 DNA primase K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 414.0
CSH1_k127_2045449_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 307.0
CSH1_k127_2045449_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000008788 248.0
CSH1_k127_2045449_3 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000000003786 122.0
CSH1_k127_2045449_4 - - - - 0.000000000000004932 81.0
CSH1_k127_2045449_5 Uncharacterised protein family UPF0058 - - - 0.0000001262 57.0
CSH1_k127_2121194_0 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 428.0
CSH1_k127_2121194_1 PFAM elongation factor Tu, domain 2 protein - - - 0.00000000000000000000000000000000000000000000000009868 189.0
CSH1_k127_2121194_2 FMN binding - - - 0.00000000000000000000000000000000000000000006254 165.0
CSH1_k127_2121194_3 KaiC K08482 - - 0.0000000000000000000000005992 115.0
CSH1_k127_2121194_4 Belongs to the peptidase S8 family K20276 - - 0.0000000000000000009003 102.0
CSH1_k127_2121194_5 domain, Protein K12287 - - 0.0002831 54.0
CSH1_k127_214023_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 6.705e-266 829.0
CSH1_k127_214023_1 PFAM Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 403.0
CSH1_k127_214023_10 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000002479 177.0
CSH1_k127_214023_11 Methyl-transferase - - - 0.000000000000000000000000000000000000000001046 166.0
CSH1_k127_214023_12 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000001836 159.0
CSH1_k127_214023_13 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000733 165.0
CSH1_k127_214023_14 Protein of unknown function (DUF996) - - - 0.000000000000000000000000000000000000009824 152.0
CSH1_k127_214023_15 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000001297 147.0
CSH1_k127_214023_16 Pfam matches to PF13186.1 SPASM, and to PF04055.16 Radical_SAM, and to PF13353.1 Fer4_12 - - - 0.000000000000000000000000000000007373 140.0
CSH1_k127_214023_17 Caspase domain - - - 0.0000000000000000000000000000001004 136.0
CSH1_k127_214023_18 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000001288 132.0
CSH1_k127_214023_19 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000004898 111.0
CSH1_k127_214023_2 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 376.0
CSH1_k127_214023_20 PFAM Peptidase C1A, papain - - - 0.000000000000000000000002331 120.0
CSH1_k127_214023_21 PFAM Peptidase C11, clostripain - - - 0.0000000000000000000000111 117.0
CSH1_k127_214023_22 Belongs to the peptidase S8 family - - - 0.0000000000000000000002645 110.0
CSH1_k127_214023_23 Domain of unknown function (DUF4870) - - - 0.000000000000000000004393 96.0
CSH1_k127_214023_24 thiolester hydrolase activity K01259,K06889,K21193 - 3.4.11.5 0.00000000000000000007969 100.0
CSH1_k127_214023_25 - - - - 0.00000000000000001503 83.0
CSH1_k127_214023_26 PKD domain K19668 - 3.2.1.91 0.0000000000000004459 93.0
CSH1_k127_214023_27 Psort location Cytoplasmic, score - - - 0.000000000000001616 86.0
CSH1_k127_214023_28 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000001099 88.0
CSH1_k127_214023_29 Nitroreductase family - - - 0.000000000006606 79.0
CSH1_k127_214023_3 PD-(D/E)XK nuclease superfamily K07465 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 363.0
CSH1_k127_214023_30 Domain of unknown function (DUF4382) - - - 0.00000000001069 72.0
CSH1_k127_214023_31 transferase activity, transferring glycosyl groups K01186,K01371,K20276 - 3.2.1.18,3.4.22.38 0.00000000006286 75.0
CSH1_k127_214023_32 Pkd domain containing protein - - - 0.0000000002269 74.0
CSH1_k127_214023_33 Peptidase family C25 - - - 0.000000003133 70.0
CSH1_k127_214023_34 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.000000003932 70.0
CSH1_k127_214023_35 - - - - 0.00000001956 58.0
CSH1_k127_214023_36 PFAM Nitroreductase - - - 0.00000006306 66.0
CSH1_k127_214023_37 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000007835 66.0
CSH1_k127_214023_38 Rhomboid family - - - 0.000001108 61.0
CSH1_k127_214023_39 EamA-like transporter family K08978 - - 0.00003515 55.0
CSH1_k127_214023_4 Chitin synthase K00752 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0051704,GO:0071944,GO:0090605,GO:0090609 2.4.1.212 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 338.0
CSH1_k127_214023_40 EamA-like transporter family - - - 0.0001156 53.0
CSH1_k127_214023_41 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.0002559 44.0
CSH1_k127_214023_42 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.0002596 52.0
CSH1_k127_214023_5 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 288.0
CSH1_k127_214023_6 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007388 279.0
CSH1_k127_214023_7 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003947 262.0
CSH1_k127_214023_8 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000009921 242.0
CSH1_k127_214023_9 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000000146 177.0
CSH1_k127_2262236_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 457.0
CSH1_k127_2262236_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 366.0
CSH1_k127_2262236_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000009011 85.0
CSH1_k127_2262236_3 Right handed beta helix region - - - 0.0000000006378 70.0
CSH1_k127_2279341_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 507.0
CSH1_k127_2279341_1 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 463.0
CSH1_k127_2279341_10 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000001429 192.0
CSH1_k127_2279341_11 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000005958 195.0
CSH1_k127_2279341_12 - K07092 - - 0.00000000000000000000000000000000000000000000007008 171.0
CSH1_k127_2279341_13 Rubrerythrin - - - 0.0000000000000000000000000000000000003131 147.0
CSH1_k127_2279341_14 redox protein regulator of disulfide bond formation - - - 0.00000000000000000000000000000001251 128.0
CSH1_k127_2279341_15 AraC-like ligand binding domain - - - 0.000000000000000000000000000002153 123.0
CSH1_k127_2279341_16 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000001217 131.0
CSH1_k127_2279341_17 Belongs to the Fur family K09825 - - 0.000000000000000000000000001247 117.0
CSH1_k127_2279341_18 B12 binding domain - - - 0.0000000000000000000006199 99.0
CSH1_k127_2279341_19 protein conserved in archaea - - - 0.00000000000000000005605 93.0
CSH1_k127_2279341_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 402.0
CSH1_k127_2279341_21 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000033 82.0
CSH1_k127_2279341_22 - K03741 - 1.20.4.1 0.0000000000008754 74.0
CSH1_k127_2279341_23 PKD domain - - - 0.0000000003519 71.0
CSH1_k127_2279341_3 Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 304.0
CSH1_k127_2279341_4 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 306.0
CSH1_k127_2279341_5 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001265 278.0
CSH1_k127_2279341_6 PFAM zinc iron permease K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004236 252.0
CSH1_k127_2279341_7 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001385 247.0
CSH1_k127_2279341_8 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000001684 223.0
CSH1_k127_2279341_9 Desulfoferrodoxin ferrous iron-binding domain K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000001705 196.0
CSH1_k127_231647_0 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000004517 241.0
CSH1_k127_231647_1 phosphorelay signal transduction system K07658 - - 0.0000000000000000000003964 103.0
CSH1_k127_231647_2 COG1522 Transcriptional regulators - - - 0.00000115 60.0
CSH1_k127_2351278_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 393.0
CSH1_k127_2351278_1 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 351.0
CSH1_k127_2351278_2 PHP-associated - - - 0.0000000000000000000000000000000542 134.0
CSH1_k127_2351278_3 metallopeptidase activity - - - 0.000000000000002713 82.0
CSH1_k127_2351278_4 Pentaxin family K12287 - - 0.00000000005806 73.0
CSH1_k127_2351278_5 PFAM class II aldolase adducin family protein - - - 0.000002612 57.0
CSH1_k127_2361387_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 514.0
CSH1_k127_2361387_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 306.0
CSH1_k127_2361387_10 PFAM FIST C domain - - - 0.000002396 60.0
CSH1_k127_2361387_2 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000044 194.0
CSH1_k127_2361387_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.000000000000000000000000000000000000000000000000002261 190.0
CSH1_k127_2361387_4 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000002241 189.0
CSH1_k127_2361387_5 SMART Prolyl 4-hydroxylase, alpha subunit - - - 0.0000000000000000000000000000000000000008096 163.0
CSH1_k127_2361387_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000001329 152.0
CSH1_k127_2361387_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP - - - 0.000000000000000000000000004722 123.0
CSH1_k127_2361387_8 Polyprenyl synthetase K02523,K13787 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000006224 113.0
CSH1_k127_2361387_9 Parallel beta-helix - - - 0.0000000000000004441 90.0
CSH1_k127_2371602_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 416.0
CSH1_k127_2371602_1 Multidrug ABC transporter ATPase K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000005171 239.0
CSH1_k127_2371602_2 LVIVD repeat-containing protein - - - 0.00000000000000000000000000000000001399 155.0
CSH1_k127_2371602_3 ABC-2 type transporter K01992 - - 0.00000000000001927 85.0
CSH1_k127_2371602_4 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0002039 47.0
CSH1_k127_2436470_0 Transcriptional regulator, TrmB - - - 0.0000000000000000000000071 106.0
CSH1_k127_2436470_1 - - - - 0.0000000000000000000005124 101.0
CSH1_k127_2436470_2 Cold shock K03704 - - 0.000000000000008515 75.0
CSH1_k127_2436470_3 - - - - 0.000000000002317 70.0
CSH1_k127_2542849_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 353.0
CSH1_k127_2542849_1 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 307.0
CSH1_k127_2542849_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000009074 234.0
CSH1_k127_2542849_3 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000001418 183.0
CSH1_k127_2570387_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000491 236.0
CSH1_k127_2570387_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000001142 186.0
CSH1_k127_2570387_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000002589 182.0
CSH1_k127_2570387_3 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000005885 168.0
CSH1_k127_2570387_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000004115 160.0
CSH1_k127_2570387_5 PFAM Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000003216 139.0
CSH1_k127_2570387_6 class II (D K and N) K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000002593 88.0
CSH1_k127_2593675_0 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 389.0
CSH1_k127_2653166_0 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000001169 244.0
CSH1_k127_2653166_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.0000000000000000000000000000000000001542 147.0
CSH1_k127_2695316_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 391.0
CSH1_k127_2695316_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 376.0
CSH1_k127_2695316_2 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 348.0
CSH1_k127_2697530_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002926 236.0
CSH1_k127_2697530_1 PFAM NHL repeat containing protein - - - 0.00000000006132 72.0
CSH1_k127_2697530_2 PKD domain - - - 0.000000003251 69.0
CSH1_k127_2699461_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 521.0
CSH1_k127_2699461_1 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 363.0
CSH1_k127_2699461_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000007601 253.0
CSH1_k127_2699461_3 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000004814 85.0
CSH1_k127_27262_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 9.492e-197 623.0
CSH1_k127_27262_1 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000003694 237.0
CSH1_k127_27262_2 - - - - 0.000000000000000000000000000000001449 136.0
CSH1_k127_27262_3 6-phosphogluconolactonase activity - - - 0.00007125 55.0
CSH1_k127_2726335_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 546.0
CSH1_k127_2726335_1 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 297.0
CSH1_k127_2726335_10 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000001855 71.0
CSH1_k127_2726335_11 proteins of PilT N-term. Vapc superfamily K07158 - - 0.0000000000008714 73.0
CSH1_k127_2726335_12 Predicted permease K07089 - - 0.00000002535 55.0
CSH1_k127_2726335_13 Pfam:KaiC - - - 0.000002452 51.0
CSH1_k127_2726335_2 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000001754 213.0
CSH1_k127_2726335_3 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000000001677 171.0
CSH1_k127_2726335_4 Belongs to the UPF0218 family K09735 - - 0.000000000000000000000000001323 119.0
CSH1_k127_2726335_5 structural constituent of ribosome K02974 - - 0.0000000000000000000000993 101.0
CSH1_k127_2726335_6 Circadian clock protein KaiC - - - 0.000000000000000000001579 104.0
CSH1_k127_2726335_7 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000001429 83.0
CSH1_k127_2726335_8 PFAM regulatory protein, ArsR K03892,K21903 - - 0.0000000000000004892 80.0
CSH1_k127_2726335_9 methyltransferase activity - - - 0.0000000000000151 81.0
CSH1_k127_2727868_0 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 359.0
CSH1_k127_2727868_1 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 339.0
CSH1_k127_2943777_0 parallel beta-helix repeat K03671 - - 0.0000001638 63.0
CSH1_k127_2943777_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000002939 59.0
CSH1_k127_2948947_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 9.203e-260 833.0
CSH1_k127_2948947_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 4.623e-219 686.0
CSH1_k127_2948947_10 PFAM GCN5-related N-acetyltransferase - - - 0.0000001732 60.0
CSH1_k127_2948947_11 AMP-binding enzyme C-terminal domain - - - 0.0000024 61.0
CSH1_k127_2948947_12 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000008986 57.0
CSH1_k127_2948947_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 618.0
CSH1_k127_2948947_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 604.0
CSH1_k127_2948947_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 370.0
CSH1_k127_2948947_5 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 347.0
CSH1_k127_2948947_6 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000745 221.0
CSH1_k127_2948947_7 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000005708 204.0
CSH1_k127_2948947_8 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000004643 193.0
CSH1_k127_2948947_9 Methyltransferase domain - - - 0.0000000000593 68.0
CSH1_k127_2961179_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 500.0
CSH1_k127_2961179_1 - - - - 0.00000000000000005181 88.0
CSH1_k127_2961179_2 PFAM Peptidase C1A, papain - - - 0.000002669 56.0
CSH1_k127_297795_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 522.0
CSH1_k127_297795_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 396.0
CSH1_k127_297795_10 Glycosyltransferase, group 2 family protein - - - 0.000003697 53.0
CSH1_k127_297795_2 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 357.0
CSH1_k127_297795_3 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 316.0
CSH1_k127_297795_4 Oxidoreductase family, C-terminal alpha beta domain K13016 - 1.1.1.335 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000142 273.0
CSH1_k127_297795_5 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001049 233.0
CSH1_k127_297795_6 Oxidoreductase family, C-terminal alpha beta domain K13016 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000008999 191.0
CSH1_k127_297795_7 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000008606 115.0
CSH1_k127_297795_8 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000009085 84.0
CSH1_k127_297795_9 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000001192 74.0
CSH1_k127_3044798_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 577.0
CSH1_k127_3044798_1 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000009946 248.0
CSH1_k127_3044798_2 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000001391 235.0
CSH1_k127_3044798_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000002399 206.0
CSH1_k127_3044798_4 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000007252 177.0
CSH1_k127_3044798_5 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000002862 148.0
CSH1_k127_3044798_6 Right handed beta helix region - - - 0.000000000000000000000000001724 132.0
CSH1_k127_3044798_7 protein conserved in archaea - - - 0.00000000000000001501 87.0
CSH1_k127_3044798_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0000000000008283 71.0
CSH1_k127_3044798_9 S-layer homology domain - - - 0.0000000006187 74.0
CSH1_k127_3102775_0 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 417.0
CSH1_k127_3102775_1 PFAM PEGA domain - - - 0.0000000000000000000000000000000000001273 160.0
CSH1_k127_3102775_2 - - - - 0.00000000000000000000000000000003845 127.0
CSH1_k127_3102775_3 - - - - 0.000003529 51.0
CSH1_k127_3145172_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 404.0
CSH1_k127_3152524_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 481.0
CSH1_k127_3152524_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 303.0
CSH1_k127_3152524_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000006713 270.0
CSH1_k127_3152524_3 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000000000009043 207.0
CSH1_k127_3152524_4 PFAM conserved K07027 - - 0.000000000000000000005456 101.0
CSH1_k127_3152524_5 PFAM regulatory protein, ArsR - - - 0.0000000000000000002645 96.0
CSH1_k127_3152524_6 Domain of unknown function (DUF1610) K07580 - - 0.000000000000002689 76.0
CSH1_k127_3152524_7 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000003038 72.0
CSH1_k127_3162105_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 2.807e-196 622.0
CSH1_k127_3162105_1 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 444.0
CSH1_k127_3162105_2 HhH-GPD family K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000638 240.0
CSH1_k127_3162105_3 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000001029 220.0
CSH1_k127_3162105_4 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000002289 100.0
CSH1_k127_3192106_0 Belongs to the peptidase S8 family K14645 - - 0.00000000000000000001356 106.0
CSH1_k127_3192106_1 PFAM NHL repeat containing protein - - - 0.0000000000000000002568 104.0
CSH1_k127_3192106_2 Sodium Bile acid symporter family K03325 - - 0.00000000000000002522 85.0
CSH1_k127_3192106_3 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.000000000004041 80.0
CSH1_k127_3192106_4 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000000001037 76.0
CSH1_k127_3192106_5 Arsenic resistance protein ArsB K03325 - - 0.000005825 50.0
CSH1_k127_3192106_6 PFAM Sodium Bile acid symporter family K03325 - - 0.00005736 46.0
CSH1_k127_3202034_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 536.0
CSH1_k127_3202034_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 379.0
CSH1_k127_3202034_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000006188 223.0
CSH1_k127_3202034_3 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 0.00000000000000002698 82.0
CSH1_k127_3202034_5 deoxyhypusine monooxygenase activity - - - 0.000001255 55.0
CSH1_k127_3202034_6 Esterase PHB depolymerase - - - 0.000003673 60.0
CSH1_k127_32094_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.474e-214 684.0
CSH1_k127_32094_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.361e-194 615.0
CSH1_k127_32094_10 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003049 266.0
CSH1_k127_32094_11 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000163 238.0
CSH1_k127_32094_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003291 235.0
CSH1_k127_32094_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001758 226.0
CSH1_k127_32094_14 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000006468 218.0
CSH1_k127_32094_15 HTH-type transcriptional regulatory protein K07728 - - 0.000000000000000000000000000000000000000000000000000000000000008073 227.0
CSH1_k127_32094_16 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000002763 203.0
CSH1_k127_32094_17 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000003001 186.0
CSH1_k127_32094_18 regulator of amino acid metabolism K07103 - - 0.0000000000000000000000000000000000002838 146.0
CSH1_k127_32094_19 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000002537 126.0
CSH1_k127_32094_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 556.0
CSH1_k127_32094_20 Peptidase family M28 - - - 0.0000000000000000000000000000001148 141.0
CSH1_k127_32094_21 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.000000000000000000000000000007594 121.0
CSH1_k127_32094_22 - - - - 0.0000000000000000000000002457 106.0
CSH1_k127_32094_23 - K00960 - 2.7.7.6 0.000000000000000002918 85.0
CSH1_k127_32094_24 secreted hydrolase - - - 0.00000000000000001561 94.0
CSH1_k127_32094_25 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.00000000000001197 79.0
CSH1_k127_32094_26 O-methyltransferase activity - - - 0.0000000000003772 77.0
CSH1_k127_32094_27 bacterial-type flagellum-dependent cell motility - - - 0.00000000004671 76.0
CSH1_k127_32094_28 - - - - 0.0000001239 57.0
CSH1_k127_32094_29 - - - - 0.0000001807 55.0
CSH1_k127_32094_3 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 544.0
CSH1_k127_32094_4 RmlD substrate binding domain K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 501.0
CSH1_k127_32094_5 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 424.0
CSH1_k127_32094_6 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 402.0
CSH1_k127_32094_7 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001224 273.0
CSH1_k127_32094_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001989 271.0
CSH1_k127_32094_9 Patched family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000589 295.0
CSH1_k127_3235687_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 413.0
CSH1_k127_3235687_1 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 388.0
CSH1_k127_3235687_2 Protein of unknown function (DUF1349) - - - 0.000000000000000000000000000001096 141.0
CSH1_k127_3235687_3 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000001399 113.0
CSH1_k127_3235687_4 parallel beta-helix repeat K03671 - - 0.0000000000000002777 91.0
CSH1_k127_3235687_5 repeat protein - - - 0.000001408 62.0
CSH1_k127_3235687_6 Autotransporter beta-domain - - - 0.00002215 55.0
CSH1_k127_3239906_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 491.0
CSH1_k127_3239906_1 agmatine deiminase activity K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 480.0
CSH1_k127_3239906_10 Domain of unknown function (DUF4314) - - - 0.00000002245 57.0
CSH1_k127_3239906_2 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 394.0
CSH1_k127_3239906_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 353.0
CSH1_k127_3239906_4 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 331.0
CSH1_k127_3239906_5 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 317.0
CSH1_k127_3239906_6 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000001732 241.0
CSH1_k127_3239906_7 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.000000000000000000000000000000000000000000000000000000003583 206.0
CSH1_k127_3239906_8 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000000000000000000002131 160.0
CSH1_k127_3239906_9 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000000000001907 101.0
CSH1_k127_3328827_0 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001179 258.0
CSH1_k127_3328827_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000007476 190.0
CSH1_k127_3328827_2 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000002776 156.0
CSH1_k127_338383_0 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000147 239.0
CSH1_k127_338383_1 Belongs to the TPP enzyme family K00158 - 1.2.3.3 0.00000000000000000000000000000000000000000000000000000000000004249 215.0
CSH1_k127_338383_2 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000004393 63.0
CSH1_k127_3387088_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 8.219e-302 948.0
CSH1_k127_3387088_1 Parallel beta-helix repeat K21449 - - 0.000000307 61.0
CSH1_k127_3387088_2 Peptidase family C25 - - - 0.000001589 61.0
CSH1_k127_3411139_0 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000006989 188.0
CSH1_k127_3411139_1 PFAM PKD domain containing protein - - - 0.000000000003276 76.0
CSH1_k127_3411139_2 Biotin-protein ligase, N terminal - - - 0.0001148 54.0
CSH1_k127_3419797_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 595.0
CSH1_k127_3419797_1 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 413.0
CSH1_k127_3419797_10 PFAM PKD domain containing protein - - - 0.000000000000003702 87.0
CSH1_k127_3419797_2 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 406.0
CSH1_k127_3419797_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 327.0
CSH1_k127_3419797_4 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002578 287.0
CSH1_k127_3419797_5 acetyltransferase - - - 0.000000000000000000000000000000000002907 145.0
CSH1_k127_3419797_6 TIGRFAM segregation and condensation protein B K06024 - - 0.00000000000000000000000000000002213 133.0
CSH1_k127_3419797_7 chromosome segregation and condensation protein ScpA K05896 - - 0.00000000000000000000000000001092 130.0
CSH1_k127_3419797_8 COG1668 ABC-type Na efflux pump, permease component - - - 0.0000000000000000000000000001828 128.0
CSH1_k127_3419797_9 cell wall organization - - - 0.000000000000000000001775 110.0
CSH1_k127_3426681_0 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 316.0
CSH1_k127_3426681_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000001588 224.0
CSH1_k127_3426681_10 transcriptional regulator K05800 - - 0.00001337 54.0
CSH1_k127_3426681_11 Protein of unknown function (DUF2510) - - - 0.0000754 52.0
CSH1_k127_3426681_12 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0001023 50.0
CSH1_k127_3426681_13 AsnC-type helix-turn-helix domain - - - 0.0005125 49.0
CSH1_k127_3426681_14 Ferritin-like domain - - - 0.000791 51.0
CSH1_k127_3426681_2 - K03561,K12287 - - 0.000000000000000000000000000000000000000000002232 188.0
CSH1_k127_3426681_3 double-strand break repair K01867,K09946 - 6.1.1.2 0.000000000000000004003 87.0
CSH1_k127_3426681_4 bacterial-type flagellum-dependent cell motility K01278,K02388,K02396,K03561,K12287 - 3.4.14.5 0.00000000000002417 85.0
CSH1_k127_3426681_5 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000001649 79.0
CSH1_k127_3426681_6 PFAM PKD domain containing protein - - - 0.0000000004954 70.0
CSH1_k127_3426681_7 alpha beta - - - 0.0000001273 63.0
CSH1_k127_3426681_8 - - - - 0.0000004251 58.0
CSH1_k127_3426681_9 PFAM NHL repeat containing protein - - - 0.0000008183 57.0
CSH1_k127_3481291_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 478.0
CSH1_k127_3481291_1 Transcriptional regulator, TrmB - - - 0.0000000000000000000000003837 109.0
CSH1_k127_3481291_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000007935 99.0
CSH1_k127_3488486_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 509.0
CSH1_k127_3488486_1 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 477.0
CSH1_k127_3488486_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 360.0
CSH1_k127_3488486_3 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 334.0
CSH1_k127_3488486_4 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000003592 236.0
CSH1_k127_3488486_5 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000001455 220.0
CSH1_k127_3488486_6 PFAM LemA - - - 0.000000000000000000000000000000000000000000000000000000000004476 213.0
CSH1_k127_3488486_7 Flavodoxin - - - 0.000000000131 68.0
CSH1_k127_3488486_8 - - - - 0.0006898 49.0
CSH1_k127_3521027_0 Cation transporter/ATPase, N-terminus K01537 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 556.0
CSH1_k127_3521027_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 477.0
CSH1_k127_3521027_10 Transcriptional regulator, TrmB - - - 0.00000000000000000000000001748 113.0
CSH1_k127_3521027_11 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000001569 78.0
CSH1_k127_3521027_12 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00001949 49.0
CSH1_k127_3521027_2 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 437.0
CSH1_k127_3521027_3 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 331.0
CSH1_k127_3521027_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000001222 245.0
CSH1_k127_3521027_5 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000009558 230.0
CSH1_k127_3521027_6 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000001089 222.0
CSH1_k127_3521027_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000005114 199.0
CSH1_k127_3521027_8 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000000003637 166.0
CSH1_k127_3521027_9 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000001912 129.0
CSH1_k127_3521103_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 345.0
CSH1_k127_3521103_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 299.0
CSH1_k127_3521103_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000874 265.0
CSH1_k127_3521103_3 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003926 248.0
CSH1_k127_3521103_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000002328 225.0
CSH1_k127_3521103_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.000000000000000000000000000000000000000000000000000006505 194.0
CSH1_k127_3521103_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000006742 182.0
CSH1_k127_3521103_7 Putative small multi-drug export protein - - - 0.000000000000000000000000000003179 125.0
CSH1_k127_3521103_8 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000001084 110.0
CSH1_k127_3586087_0 PFAM multi antimicrobial extrusion protein MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 488.0
CSH1_k127_3586087_1 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 432.0
CSH1_k127_3586087_2 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 342.0
CSH1_k127_3586087_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000007161 171.0
CSH1_k127_3586087_4 Vacuolar protein sorting-associated protein 62 - GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005783,GO:0006605,GO:0006623,GO:0006810,GO:0006886,GO:0007034,GO:0008104,GO:0008150,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0031090,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072665,GO:0072666,GO:0098588,GO:0098805,GO:0098852 - 0.0000000000000006889 91.0
CSH1_k127_3645660_0 metallopeptidase activity - - - 0.0000000005677 65.0
CSH1_k127_3717262_0 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 477.0
CSH1_k127_3717262_1 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 425.0
CSH1_k127_3717262_10 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000001441 183.0
CSH1_k127_3717262_11 Phosphate-binding protein PstS 2 K02040 - - 0.0000000000000000000000000000000000000000000002249 178.0
CSH1_k127_3717262_12 amino acid K03294 - - 0.0000000000000000000000000000000000321 140.0
CSH1_k127_3717262_13 transcriptional - - - 0.00000000000000000000000007655 110.0
CSH1_k127_3717262_14 PFAM regulatory protein, ArsR K03892,K21903 - - 0.0000000000000000004806 89.0
CSH1_k127_3717262_15 extracellular matrix structural constituent - - - 0.000000000001615 79.0
CSH1_k127_3717262_2 PhoU domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 364.0
CSH1_k127_3717262_3 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 334.0
CSH1_k127_3717262_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001368 257.0
CSH1_k127_3717262_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000002395 218.0
CSH1_k127_3717262_6 - - - - 0.0000000000000000000000000000000000000000000000000003177 194.0
CSH1_k127_3717262_7 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000397 191.0
CSH1_k127_3717262_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000006302 188.0
CSH1_k127_3717262_9 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000001694 198.0
CSH1_k127_3720328_0 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003769 275.0
CSH1_k127_3720328_1 Type II secretion system K07333 - - 0.00000000000000000000000000000002442 137.0
CSH1_k127_3720328_2 Type II secretion system K07333 - - 0.0000000000000000000000000000001121 135.0
CSH1_k127_3720328_3 Metallo-peptidase family M12 - - - 0.00000000000000000000000125 121.0
CSH1_k127_3720328_4 PGAP1-like protein - - - 0.000000000000008648 88.0
CSH1_k127_3720328_5 cell wall organization K01448 - 3.5.1.28 0.000000005965 69.0
CSH1_k127_3720328_6 Calx-beta domain - - - 0.000007299 59.0
CSH1_k127_3732886_0 phosphoenolpyruvate carboxykinase (GTP) activity K01596,K01610 - 4.1.1.32,4.1.1.49 2.639e-241 760.0
CSH1_k127_3732886_1 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 610.0
CSH1_k127_3732886_10 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 341.0
CSH1_k127_3732886_11 deoxyribonuclease I activity K06131,K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008408 345.0
CSH1_k127_3732886_12 ABC transporter K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 317.0
CSH1_k127_3732886_13 Belongs to the peptidase S16 family K06870 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000831 312.0
CSH1_k127_3732886_14 calcium proton exchanger K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001703 286.0
CSH1_k127_3732886_15 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002375 268.0
CSH1_k127_3732886_16 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000001259 239.0
CSH1_k127_3732886_17 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002927 235.0
CSH1_k127_3732886_18 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000001874 232.0
CSH1_k127_3732886_19 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000004049 212.0
CSH1_k127_3732886_2 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 597.0
CSH1_k127_3732886_20 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000006285 218.0
CSH1_k127_3732886_21 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000000000000000000000000000000000000000000000001001 211.0
CSH1_k127_3732886_22 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000001183 204.0
CSH1_k127_3732886_23 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000007417 199.0
CSH1_k127_3732886_24 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000004171 193.0
CSH1_k127_3732886_25 S-acyltransferase activity K00627,K03310,K03578,K12132 - 2.3.1.12,2.7.11.1,3.6.4.13 0.000000000000000000000000000000000000000000000000008962 193.0
CSH1_k127_3732886_26 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000002254 190.0
CSH1_k127_3732886_27 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000003639 178.0
CSH1_k127_3732886_28 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000002842 168.0
CSH1_k127_3732886_29 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000008591 145.0
CSH1_k127_3732886_3 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 558.0
CSH1_k127_3732886_30 Predicted SAM-dependent RNA methyltransferase - - - 0.0000000000000000000000000000002573 132.0
CSH1_k127_3732886_31 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000003529 133.0
CSH1_k127_3732886_32 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000000000000000000002198 124.0
CSH1_k127_3732886_33 Rhomboid family - - - 0.000000000000000000000003046 114.0
CSH1_k127_3732886_34 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000000000006966 91.0
CSH1_k127_3732886_35 Zinc metalloprotease (Elastase) - - - 0.000000000000000001338 99.0
CSH1_k127_3732886_36 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000001775 92.0
CSH1_k127_3732886_37 PFAM Nitroreductase - - - 0.000000000000002603 89.0
CSH1_k127_3732886_38 Micrococcal nuclease (thermonuclease) homologs K01174,K02238 - 3.1.31.1 0.0000000186 68.0
CSH1_k127_3732886_39 APHP domain protein - - - 0.0000009809 60.0
CSH1_k127_3732886_4 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 501.0
CSH1_k127_3732886_40 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000005157 58.0
CSH1_k127_3732886_41 Pectate lyase - - - 0.00003702 57.0
CSH1_k127_3732886_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147,K22465 - 4.1.99.17,4.1.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 489.0
CSH1_k127_3732886_6 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 438.0
CSH1_k127_3732886_7 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 405.0
CSH1_k127_3732886_8 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 400.0
CSH1_k127_3732886_9 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 370.0
CSH1_k127_3777251_0 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 335.0
CSH1_k127_3777251_1 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000001124 123.0
CSH1_k127_3777251_2 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.000000004708 68.0
CSH1_k127_3777251_3 cell wall organization - - - 0.00000004552 64.0
CSH1_k127_37973_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000001188 148.0
CSH1_k127_37973_1 Belongs to the peptidase S8 family - - - 0.0000000000000000003475 104.0
CSH1_k127_37973_2 PFAM NHL repeat containing protein - - - 0.000000000000001379 92.0
CSH1_k127_37973_3 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.00002459 56.0
CSH1_k127_3798282_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000353 258.0
CSH1_k127_3798282_1 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000001012 215.0
CSH1_k127_3798282_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000003105 81.0
CSH1_k127_3801493_0 agmatine deiminase activity K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 552.0
CSH1_k127_3801493_1 agmatine deiminase activity K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 398.0
CSH1_k127_3801493_2 Domain of unknown function (DUF4314) - - - 0.0000001731 55.0
CSH1_k127_3801493_3 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0001699 55.0
CSH1_k127_3816258_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 2.23e-268 856.0
CSH1_k127_3816258_1 Aromatic amino acid lyase K01745 - 4.3.1.3 1.591e-263 819.0
CSH1_k127_3816258_10 Propeptide_C25 - - - 0.00000000005262 75.0
CSH1_k127_3816258_11 Peptidase family C25 - - - 0.00000001256 67.0
CSH1_k127_3816258_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 1.793e-226 714.0
CSH1_k127_3816258_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 479.0
CSH1_k127_3816258_4 Glycerate kinase K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 325.0
CSH1_k127_3816258_5 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000308 135.0
CSH1_k127_3816258_6 Peptidase family M28 - - - 0.000000000000000000000001058 117.0
CSH1_k127_3816258_7 snRNP Sm proteins K04796 - - 0.000000000000000007554 85.0
CSH1_k127_3816258_9 PQQ enzyme repeat - - - 0.000000000003011 81.0
CSH1_k127_3834987_0 Multicopper - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 498.0
CSH1_k127_3834987_1 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 377.0
CSH1_k127_3834987_2 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 370.0
CSH1_k127_3834987_3 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000002881 214.0
CSH1_k127_3834987_4 SCO1/SenC - - - 0.000000000000000000000000000000000000000000000000000001766 196.0
CSH1_k127_3834987_5 - - - - 0.00000000000000000000006685 107.0
CSH1_k127_3834987_6 Periplasmic copper-binding protein (NosD) - - - 0.000000000003905 72.0
CSH1_k127_3834987_7 4Fe-4S single cluster domain K05337 - - 0.00000005122 56.0
CSH1_k127_3834987_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0001502 50.0
CSH1_k127_3854972_0 Collagen triple helix repeat (20 copies) - - - 0.00000000000000000001193 106.0
CSH1_k127_3854972_1 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000000002967 66.0
CSH1_k127_3854972_2 - - - - 0.000124 51.0
CSH1_k127_3855329_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 4.339e-196 640.0
CSH1_k127_3855329_1 tRNA binding K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 498.0
CSH1_k127_3855329_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 429.0
CSH1_k127_3855329_3 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 388.0
CSH1_k127_3855329_4 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 360.0
CSH1_k127_3855329_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000004777 207.0
CSH1_k127_3855329_6 but it may be involved in stabilization of the trimeric complex - - - 0.000004884 52.0
CSH1_k127_3855329_7 Transcriptional regulator K05800 - - 0.000031 53.0
CSH1_k127_3866271_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 381.0
CSH1_k127_3866271_1 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000001916 168.0
CSH1_k127_3866271_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000001874 127.0
CSH1_k127_3866271_3 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.000000000000000000000000004349 121.0
CSH1_k127_3866271_4 phosphoesterase RecJ domain protein - - - 0.0001665 45.0
CSH1_k127_3888189_0 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000005161 120.0
CSH1_k127_3888189_1 membrane - - - 0.0000001912 61.0
CSH1_k127_3888189_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00003616 50.0
CSH1_k127_3910818_0 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 439.0
CSH1_k127_3910818_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 349.0
CSH1_k127_3910818_10 - - - - 0.0000000000000000000000001747 112.0
CSH1_k127_3910818_11 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000005619 92.0
CSH1_k127_3910818_12 Major facilitator Superfamily K08162,K08226,K16211 - - 0.00000000000003853 84.0
CSH1_k127_3910818_13 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000000008182 74.0
CSH1_k127_3910818_14 signal transduction protein with CBS domains - - - 0.0000000005158 71.0
CSH1_k127_3910818_15 membrane-associated protein domain - - - 0.0000000008937 71.0
CSH1_k127_3910818_16 beta-galactosidase activity - - - 0.000000002837 70.0
CSH1_k127_3910818_17 glucose sorbosone - - - 0.00000004289 63.0
CSH1_k127_3910818_18 lycopene cyclase - - - 0.00000214 54.0
CSH1_k127_3910818_19 membrane-associated protein domain - - - 0.000006734 59.0
CSH1_k127_3910818_2 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000008512 237.0
CSH1_k127_3910818_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000005738 228.0
CSH1_k127_3910818_4 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.00000000000000000000000000000000000000000000000000000000001281 213.0
CSH1_k127_3910818_5 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000007773 215.0
CSH1_k127_3910818_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000007011 179.0
CSH1_k127_3910818_7 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000002741 164.0
CSH1_k127_3910818_8 pyridoxamine 5'-phosphate oxidase-related FMN-binding K07005 - - 0.0000000000000000000000000000000000000001648 155.0
CSH1_k127_3910818_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000001995 128.0
CSH1_k127_3917472_0 Psort location Cytoplasmic, score - - - 0.0 1273.0
CSH1_k127_3917472_1 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1030.0
CSH1_k127_3917472_10 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000001479 223.0
CSH1_k127_3917472_11 heterodisulfide reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000004477 216.0
CSH1_k127_3917472_12 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000005204 218.0
CSH1_k127_3917472_13 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000002831 196.0
CSH1_k127_3917472_14 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000004107 184.0
CSH1_k127_3917472_15 OsmC-like protein K09136 - - 0.000000000000000000000000000000000000007573 149.0
CSH1_k127_3917472_16 hydrogenase maturation protease K03605 - - 0.00000000000000000000001325 107.0
CSH1_k127_3917472_17 4Fe-4S dicluster domain K03390,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000002068 102.0
CSH1_k127_3917472_18 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000006164 98.0
CSH1_k127_3917472_19 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000001054 87.0
CSH1_k127_3917472_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.441e-212 677.0
CSH1_k127_3917472_20 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000002142 79.0
CSH1_k127_3917472_21 PFAM Methyltransferase type 11 - - - 0.000000000006591 74.0
CSH1_k127_3917472_22 Transglutaminase/protease-like homologues - - - 0.0000000006978 70.0
CSH1_k127_3917472_23 Bacterial transferase hexapeptide - - - 0.000000006364 66.0
CSH1_k127_3917472_24 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00004167 49.0
CSH1_k127_3917472_25 PFAM transglutaminase domain protein - - - 0.0007709 51.0
CSH1_k127_3917472_3 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 613.0
CSH1_k127_3917472_4 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 564.0
CSH1_k127_3917472_5 Nickel-dependent hydrogenase K00436,K14126 - 1.12.1.2,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 485.0
CSH1_k127_3917472_6 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 463.0
CSH1_k127_3917472_7 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002321 278.0
CSH1_k127_3917472_8 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005442 262.0
CSH1_k127_3917472_9 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00125 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000005322 266.0
CSH1_k127_3919622_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 312.0
CSH1_k127_3919622_1 by modhmm K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000171 249.0
CSH1_k127_3919622_2 Glycogen recognition site of AMP-activated protein kinase K01442 - 3.5.1.24 0.00000000000000000000000000000000002715 149.0
CSH1_k127_3919622_3 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000000003013 111.0
CSH1_k127_3919622_4 NHL repeat containing protein K01113 - 3.1.3.1 0.000000000886 72.0
CSH1_k127_3919622_5 Polysaccharide deacetylase K01452,K14659,K22278 - 3.5.1.104,3.5.1.41 0.00002357 57.0
CSH1_k127_3923566_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000001964 230.0
CSH1_k127_3947059_0 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000002507 235.0
CSH1_k127_3947059_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000001233 138.0
CSH1_k127_3947059_2 Protein of unknown function (DUF1624) - - - 0.0000000000000000000272 98.0
CSH1_k127_3947059_3 peptidase activity, acting on L-amino acid peptides K01337,K13735,K20276 - 3.4.21.50 0.00000003393 68.0
CSH1_k127_3981950_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1260.0
CSH1_k127_3981950_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 555.0
CSH1_k127_3981950_2 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 315.0
CSH1_k127_3981950_3 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000005046 177.0
CSH1_k127_3981950_4 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000000000000000001979 141.0
CSH1_k127_3981950_5 - - - - 0.0002357 51.0
CSH1_k127_3994941_0 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000008411 228.0
CSH1_k127_3994941_1 DsrE/DsrF/DrsH-like family - - - 0.000000000000000004067 91.0
CSH1_k127_3994941_2 CrtC N-terminal lipocalin domain - - - 0.000000001776 71.0
CSH1_k127_4004282_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 438.0
CSH1_k127_4004282_1 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 415.0
CSH1_k127_4004282_10 Belongs to the glycosyl hydrolase 43 family K01278,K03561,K12287 - 3.4.14.5 0.00000000000000000002706 103.0
CSH1_k127_4004282_11 - - - - 0.00000000000000006615 83.0
CSH1_k127_4004282_12 lactoylglutathione lyase activity - - - 0.0000000001077 69.0
CSH1_k127_4004282_13 Peptidase family C25 - - - 0.000007113 59.0
CSH1_k127_4004282_14 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00001363 54.0
CSH1_k127_4004282_2 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 312.0
CSH1_k127_4004282_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 310.0
CSH1_k127_4004282_4 Alpha-amylase domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 297.0
CSH1_k127_4004282_5 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002094 280.0
CSH1_k127_4004282_6 Rad51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002898 243.0
CSH1_k127_4004282_7 metal ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000003692 232.0
CSH1_k127_4004282_8 Pfam:KaiC - - - 0.00000000000000000000000000000002623 136.0
CSH1_k127_4004282_9 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000001899 102.0
CSH1_k127_4059074_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 3.678e-221 702.0
CSH1_k127_4059074_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 397.0
CSH1_k127_4059074_10 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.00000000001132 77.0
CSH1_k127_4059074_11 - - - - 0.000002452 51.0
CSH1_k127_4059074_2 ATP-grasp enzyme K17810 - 6.3.1.12 0.000000000000000000000000000000000000000000000000000008865 205.0
CSH1_k127_4059074_3 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000006302 176.0
CSH1_k127_4059074_4 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000000000000319 166.0
CSH1_k127_4059074_5 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.00000000000000000000000000000000000000008919 159.0
CSH1_k127_4059074_6 Belongs to the PDCD5 family K06875 - - 0.000000000000000001437 89.0
CSH1_k127_4059074_7 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000126 91.0
CSH1_k127_4059074_8 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.00000000000006882 76.0
CSH1_k127_4059074_9 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.00000000000007735 72.0
CSH1_k127_4081148_0 membrane-associated protein domain - - - 0.000001422 61.0
CSH1_k127_4099891_0 Type II/IV secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 550.0
CSH1_k127_4099891_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 487.0
CSH1_k127_4099891_2 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 400.0
CSH1_k127_4099891_3 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 338.0
CSH1_k127_4099891_4 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000003898 82.0
CSH1_k127_4099891_5 Helix-turn-helix K07108 - - 0.00000000000003938 76.0
CSH1_k127_4099891_6 - - - - 0.00000599 56.0
CSH1_k127_4099891_7 - - - - 0.00002069 51.0
CSH1_k127_4134869_0 Heat shock 70 kDa protein K04043 - - 2.227e-241 760.0
CSH1_k127_4134869_1 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 6.912e-235 741.0
CSH1_k127_4134869_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000005958 95.0
CSH1_k127_4134869_11 Universal stress protein family - - - 0.00000000000001501 79.0
CSH1_k127_4134869_12 Domain of unknown function (DUF2341) - - - 0.000000000004443 80.0
CSH1_k127_4134869_13 pathogenesis K13669 - - 0.00000000004034 77.0
CSH1_k127_4134869_14 GDSL-like Lipase/Acylhydrolase family K06882 - - 0.00005138 57.0
CSH1_k127_4134869_2 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 8.428e-220 695.0
CSH1_k127_4134869_3 Aconitase family (aconitate hydratase) K01703,K01705,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35,4.2.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 454.0
CSH1_k127_4134869_4 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 344.0
CSH1_k127_4134869_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001403 269.0
CSH1_k127_4134869_6 Chlorophyllase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000006704 226.0
CSH1_k127_4134869_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000009907 190.0
CSH1_k127_4134869_8 ATP-binding region ATPase domain protein K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.00000000000000000000000000000000000000000000000002229 198.0
CSH1_k127_4134869_9 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000004293 166.0
CSH1_k127_4154367_0 type II secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 573.0
CSH1_k127_4154367_1 PFAM Type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 540.0
CSH1_k127_4154367_2 PFAM Type II secretion system F domain K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000718 294.0
CSH1_k127_4154367_3 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000000000000001747 146.0
CSH1_k127_4154367_4 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000000000000000000007713 141.0
CSH1_k127_4154367_5 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000000000000000004702 140.0
CSH1_k127_4154367_6 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000005811 90.0
CSH1_k127_4159602_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 464.0
CSH1_k127_4159602_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 387.0
CSH1_k127_4159602_10 Parallel beta-helix repeats - - - 0.000000000006399 79.0
CSH1_k127_4159602_12 Cobalamin biosynthesis protein CobT VWA domain - - - 0.0000005435 63.0
CSH1_k127_4159602_2 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 302.0
CSH1_k127_4159602_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002071 260.0
CSH1_k127_4159602_4 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000002202 175.0
CSH1_k127_4159602_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000002644 164.0
CSH1_k127_4159602_6 hydroxylase K15746 - 1.14.15.24 0.00000000000000000000000000000000001148 140.0
CSH1_k127_4159602_7 Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000000000000000002155 141.0
CSH1_k127_4159602_8 chitinase K01183 - 3.2.1.14 0.000000000000004743 89.0
CSH1_k127_4159602_9 helix_turn_helix ASNC type K03718 - - 0.0000000000001296 76.0
CSH1_k127_415970_0 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 441.0
CSH1_k127_415970_1 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000001151 177.0
CSH1_k127_415970_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000001486 152.0
CSH1_k127_415970_3 PFAM Peptidase C1A, papain - - - 0.00000000000000004138 96.0
CSH1_k127_415970_4 Protein of unknown function (DUF504) K09715 - - 0.000000007509 60.0
CSH1_k127_4189782_0 TIGRFAM Small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 399.0
CSH1_k127_4189782_1 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 334.0
CSH1_k127_4189782_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002668 258.0
CSH1_k127_4189782_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000003893 226.0
CSH1_k127_4189782_4 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000005741 217.0
CSH1_k127_4189782_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000006384 121.0
CSH1_k127_4203805_0 Helix-turn-helix XRE-family like proteins K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000007499 237.0
CSH1_k127_4203805_1 Belongs to the peptidase S8 family K20276 - - 0.0000000000000000000000000005518 132.0
CSH1_k127_4203805_2 Aldo/keto reductase family - - - 0.000000000000000000000008633 101.0
CSH1_k127_4203805_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000001712 72.0
CSH1_k127_4203805_4 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.00001629 48.0
CSH1_k127_4203805_5 Peptidase family C25 - - - 0.00002427 56.0
CSH1_k127_4204975_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.813e-211 668.0
CSH1_k127_4204975_1 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000000000000000000134 172.0
CSH1_k127_4204975_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000005488 89.0
CSH1_k127_4204975_3 Protein of unknown function (DUF1624) - - - 0.0008668 42.0
CSH1_k127_4221792_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 335.0
CSH1_k127_4221792_1 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000001985 126.0
CSH1_k127_4221792_2 - - - - 0.0000000000000000000004966 96.0
CSH1_k127_4221792_3 - - - - 0.00000003119 59.0
CSH1_k127_4274284_0 amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000002058 229.0
CSH1_k127_4274284_1 Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.00001349 57.0
CSH1_k127_4314157_0 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 319.0
CSH1_k127_4314157_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003515 228.0
CSH1_k127_4314157_10 - - - - 0.000008338 49.0
CSH1_k127_4314157_11 hemerythrin HHE cation binding domain - - - 0.0005558 48.0
CSH1_k127_4314157_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000004964 177.0
CSH1_k127_4314157_3 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000009361 178.0
CSH1_k127_4314157_4 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000001057 156.0
CSH1_k127_4314157_5 Lrp/AsnC ligand binding domain - - - 0.0000000000000000002129 90.0
CSH1_k127_4314157_6 Glutaredoxin - - - 0.000000000000000005823 88.0
CSH1_k127_4314157_7 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000008269 93.0
CSH1_k127_4314157_8 sequence-specific DNA binding K07108 - - 0.00000000000003244 76.0
CSH1_k127_4314157_9 alginic acid biosynthetic process K20276 - - 0.000000002917 66.0
CSH1_k127_4362400_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 2.216e-235 737.0
CSH1_k127_4362400_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.0000008019 51.0
CSH1_k127_4364995_0 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 332.0
CSH1_k127_4364995_1 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000005117 192.0
CSH1_k127_4364995_2 PRC-barrel domain - - - 0.00000000000005626 76.0
CSH1_k127_4364995_3 - - - - 0.000006353 50.0
CSH1_k127_4364995_4 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0001026 48.0
CSH1_k127_4381922_0 flavodoxin nitric oxide synthase - - - 2.914e-198 624.0
CSH1_k127_4381922_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 602.0
CSH1_k127_4381922_10 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001 272.0
CSH1_k127_4381922_11 SMART zinc finger, CDGSH-type domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004423 252.0
CSH1_k127_4381922_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001469 244.0
CSH1_k127_4381922_13 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000005688 211.0
CSH1_k127_4381922_14 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000001196 218.0
CSH1_k127_4381922_15 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000002564 207.0
CSH1_k127_4381922_16 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000003802 207.0
CSH1_k127_4381922_17 RibD C-terminal domain K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000000008949 193.0
CSH1_k127_4381922_18 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000004116 182.0
CSH1_k127_4381922_19 Pas domain - - - 0.000000000000000000000000000000000000000000000005164 183.0
CSH1_k127_4381922_2 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 426.0
CSH1_k127_4381922_20 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000001943 178.0
CSH1_k127_4381922_21 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000002708 168.0
CSH1_k127_4381922_22 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000003123 186.0
CSH1_k127_4381922_23 PFAM NAD dependent epimerase dehydratase family - - - 0.000000000000000000000000000000000000000009714 168.0
CSH1_k127_4381922_24 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.000000000000000000000000000000000000001389 168.0
CSH1_k127_4381922_25 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000001941 156.0
CSH1_k127_4381922_26 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000004057 140.0
CSH1_k127_4381922_27 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000001236 133.0
CSH1_k127_4381922_28 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000001973 136.0
CSH1_k127_4381922_29 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000005238 119.0
CSH1_k127_4381922_3 aminopeptidase K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 422.0
CSH1_k127_4381922_30 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000005088 112.0
CSH1_k127_4381922_31 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.00000000000000000000000000542 123.0
CSH1_k127_4381922_32 aminopeptidase activity K05994 - 3.4.11.10 0.000000000000000000001067 109.0
CSH1_k127_4381922_33 response regulator, receiver K07668,K07669 - - 0.000000000000000000001901 98.0
CSH1_k127_4381922_34 Peptidase family M28 K04771 - 3.4.21.107 0.00000000000000000001053 106.0
CSH1_k127_4381922_35 Papain family cysteine protease - - - 0.0000000000000000001879 103.0
CSH1_k127_4381922_36 - - - - 0.000000000000000001309 98.0
CSH1_k127_4381922_37 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.00000000000000001414 98.0
CSH1_k127_4381922_38 Propeptide_C25 - - - 0.0000000000000001238 94.0
CSH1_k127_4381922_39 PFAM Peptidase C1A, papain - - - 0.0000000000000008551 91.0
CSH1_k127_4381922_4 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 411.0
CSH1_k127_4381922_40 protein contain chitin-binding domain type 3 - - - 0.00000000000002166 87.0
CSH1_k127_4381922_41 Archaeal Type IV pilin, N-terminal - - - 0.00000000000003346 86.0
CSH1_k127_4381922_42 Protein of unknown function (DUF3795) - - - 0.00000000000005045 77.0
CSH1_k127_4381922_43 PKD domain containing protein - - - 0.00000000000005286 88.0
CSH1_k127_4381922_44 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000879 81.0
CSH1_k127_4381922_45 Sugar (and other) transporter K08196,K08369 - - 0.0000000001439 73.0
CSH1_k127_4381922_46 PFAM conserved K07027 - - 0.0000000002347 72.0
CSH1_k127_4381922_47 Lrp/AsnC ligand binding domain - - - 0.000000006327 59.0
CSH1_k127_4381922_48 - - - - 0.0000001824 58.0
CSH1_k127_4381922_49 Thioredoxin K03671 - - 0.000000303 57.0
CSH1_k127_4381922_5 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 402.0
CSH1_k127_4381922_50 Fibronectin type 3 domain K21571 - - 0.0000004347 62.0
CSH1_k127_4381922_51 2TM domain - - - 0.0000006053 55.0
CSH1_k127_4381922_52 Transglutaminase-like superfamily - - - 0.0000008118 61.0
CSH1_k127_4381922_53 Belongs to the peptidase S8 family - - - 0.000001049 63.0
CSH1_k127_4381922_54 aminopeptidase activity - - - 0.0000023 60.0
CSH1_k127_4381922_55 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.000006792 61.0
CSH1_k127_4381922_56 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.000008651 58.0
CSH1_k127_4381922_57 COG1522 Transcriptional regulators K03719 - - 0.0002641 50.0
CSH1_k127_4381922_58 Belongs to the peptidase S8 family - - - 0.0004478 54.0
CSH1_k127_4381922_59 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0004524 52.0
CSH1_k127_4381922_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 377.0
CSH1_k127_4381922_60 Transglutaminase-like superfamily - - - 0.0005611 51.0
CSH1_k127_4381922_61 metallopeptidase activity - - - 0.0005982 52.0
CSH1_k127_4381922_62 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0008302 53.0
CSH1_k127_4381922_7 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 373.0
CSH1_k127_4381922_8 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 344.0
CSH1_k127_4381922_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 318.0
CSH1_k127_4404488_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 470.0
CSH1_k127_4404488_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 366.0
CSH1_k127_4404488_10 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives - - - 0.000000000000000006565 88.0
CSH1_k127_4404488_11 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00003737 50.0
CSH1_k127_4404488_2 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 321.0
CSH1_k127_4404488_3 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 302.0
CSH1_k127_4404488_4 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 299.0
CSH1_k127_4404488_5 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009267 297.0
CSH1_k127_4404488_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000001791 212.0
CSH1_k127_4404488_7 SMART Excinuclease ABC, C subunit - - - 0.0000000000000000000000000000000000003337 144.0
CSH1_k127_4404488_8 Divalent ion tolerance protein K03926 - - 0.0000000000000000000004423 99.0
CSH1_k127_4404488_9 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000006966 91.0
CSH1_k127_4437725_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 598.0
CSH1_k127_4437725_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 466.0
CSH1_k127_4437725_2 Belongs to the phosphohexose mutase family K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001089 269.0
CSH1_k127_4437725_3 PFAM transferase hexapeptide repeat containing protein K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000004412 218.0
CSH1_k127_4437725_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000007812 164.0
CSH1_k127_4437725_5 Phage integrase family K04763 - - 0.00000000000000000000000000000000000002893 154.0
CSH1_k127_4437725_6 Caspase domain - - - 0.0000006366 60.0
CSH1_k127_4481105_0 oxidoreductase activity - - - 0.0000000000000000000006611 106.0
CSH1_k127_4499821_0 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 454.0
CSH1_k127_4499821_1 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 424.0
CSH1_k127_4499821_2 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 335.0
CSH1_k127_4499821_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 315.0
CSH1_k127_4499821_4 Starch synthase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 318.0
CSH1_k127_4499821_5 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 301.0
CSH1_k127_4499821_6 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000113 273.0
CSH1_k127_4499821_7 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006209 266.0
CSH1_k127_4499821_8 TIGRFAM glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000001529 185.0
CSH1_k127_4499821_9 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000002017 106.0
CSH1_k127_4537500_0 KaiC K08482 - - 0.00000000000000000000000003676 118.0
CSH1_k127_4537500_1 Domain of unknown function (DUF1735) - - - 0.00000005856 57.0
CSH1_k127_4559046_0 Radical SAM domain protein - - - 0.000000000000000000000000000000000003287 147.0
CSH1_k127_4559046_1 Peptidase C10 family - - - 0.00000000000003495 85.0
CSH1_k127_4586599_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 412.0
CSH1_k127_4586599_1 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 362.0
CSH1_k127_4586599_2 TIGRFAM ribosomal RNA small subunit methyltransferase RsmB K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 357.0
CSH1_k127_4586599_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002991 283.0
CSH1_k127_4586599_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007118 271.0
CSH1_k127_4586599_5 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000006579 258.0
CSH1_k127_4586599_6 - - - - 0.000000000005615 78.0
CSH1_k127_4602521_0 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 325.0
CSH1_k127_4602521_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001389 245.0
CSH1_k127_466508_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000006339 267.0
CSH1_k127_466508_1 geranylgeranyl reductase K00311 - 1.5.5.1 0.000000000002818 69.0
CSH1_k127_4665878_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.968e-195 620.0
CSH1_k127_4665878_1 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 319.0
CSH1_k127_4665878_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000002545 269.0
CSH1_k127_4665878_3 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000009574 200.0
CSH1_k127_4695947_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 486.0
CSH1_k127_4695947_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 353.0
CSH1_k127_4695947_10 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.000000000000000000000000000000000000003816 160.0
CSH1_k127_4695947_11 4Fe-4S binding domain protein - - - 0.000000000000000000000000000000000000007143 156.0
CSH1_k127_4695947_12 Uncharacterised protein family (UPF0179) K09730 - - 0.0000000000000000000000000000000001233 138.0
CSH1_k127_4695947_13 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000005282 147.0
CSH1_k127_4695947_14 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.00000000000000000000000000000001797 139.0
CSH1_k127_4695947_15 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000000000000000000001301 121.0
CSH1_k127_4695947_16 - - - - 0.000000000000000000000001196 108.0
CSH1_k127_4695947_17 membrane - - - 0.000000000000000000000004487 115.0
CSH1_k127_4695947_18 Thioredoxin-like - - - 0.000000000004147 73.0
CSH1_k127_4695947_19 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000002274 59.0
CSH1_k127_4695947_2 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 355.0
CSH1_k127_4695947_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 353.0
CSH1_k127_4695947_4 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 337.0
CSH1_k127_4695947_5 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 310.0
CSH1_k127_4695947_6 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 311.0
CSH1_k127_4695947_7 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 302.0
CSH1_k127_4695947_8 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000009529 191.0
CSH1_k127_4695947_9 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000002854 158.0
CSH1_k127_4715750_0 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 468.0
CSH1_k127_4715750_1 Resolvase, N terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001911 284.0
CSH1_k127_4715750_10 Parallel beta-helix repeats - - - 0.0000000000000000000007926 105.0
CSH1_k127_4715750_11 Recombinase - - - 0.000000000000000000511 96.0
CSH1_k127_4715750_12 dihydromethanopterin reductase activity K00176,K06411,K12527 - 1.2.7.3,1.97.1.9 0.0000000000000002721 81.0
CSH1_k127_4715750_13 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.00000001162 60.0
CSH1_k127_4715750_14 protein contain chitin-binding domain type 3 K01183,K21606 - 3.2.1.14,3.2.1.202 0.00000009281 63.0
CSH1_k127_4715750_15 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.0003526 52.0
CSH1_k127_4715750_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004419 271.0
CSH1_k127_4715750_3 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000002226 242.0
CSH1_k127_4715750_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000002799 241.0
CSH1_k127_4715750_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000003923 228.0
CSH1_k127_4715750_6 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000003204 192.0
CSH1_k127_4715750_7 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000008068 182.0
CSH1_k127_4715750_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000005978 178.0
CSH1_k127_4715750_9 Ribosomal protein S8e K02995 - - 0.000000000000000000000000000000000001629 143.0
CSH1_k127_4859448_0 peptidase activity, acting on L-amino acid peptides K07752 - 3.4.17.22 0.00000000000000000000000000000000000000000000000000000000000088 236.0
CSH1_k127_4859448_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000005084 172.0
CSH1_k127_4859448_2 Protein of unknown function (DUF4256) - - - 0.0000000000000000000000000000000000000000006387 159.0
CSH1_k127_4859448_3 PKD domain containing protein - - - 0.000000000000002207 91.0
CSH1_k127_4886772_0 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 391.0
CSH1_k127_4886772_1 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 330.0
CSH1_k127_4886772_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00004176 56.0
CSH1_k127_4886772_2 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 308.0
CSH1_k127_4886772_3 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 295.0
CSH1_k127_4886772_4 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002265 236.0
CSH1_k127_4886772_5 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000001021 177.0
CSH1_k127_4886772_6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000004357 183.0
CSH1_k127_4886772_7 - - - - 0.00000000000000000000000000000000000003587 149.0
CSH1_k127_4886772_8 PKD domain containing protein - - - 0.0000000000000004207 93.0
CSH1_k127_4886772_9 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA - - - 0.000005684 57.0
CSH1_k127_4948368_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 498.0
CSH1_k127_4948368_1 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00186 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 366.0
CSH1_k127_4948368_10 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000007473 162.0
CSH1_k127_4948368_11 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.000000000000000000000000000000000001523 149.0
CSH1_k127_4948368_12 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000004825 115.0
CSH1_k127_4948368_13 SMART Cystathionine beta-synthase, core - - - 0.000000000000000000000000001983 121.0
CSH1_k127_4948368_14 - - - - 0.000000000000000000001554 98.0
CSH1_k127_4948368_15 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.000000000000000000002379 98.0
CSH1_k127_4948368_16 response regulator, receiver K01768,K11527,K19617 - 2.7.13.3,4.6.1.1 0.000000000000000000007423 96.0
CSH1_k127_4948368_17 PFAM CBS domain containing protein - - - 0.0000000000000000000331 94.0
CSH1_k127_4948368_18 AMP binding - - - 0.0000000000000003712 83.0
CSH1_k127_4948368_19 Thiamine-binding protein - - - 0.0000000000000007035 81.0
CSH1_k127_4948368_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 319.0
CSH1_k127_4948368_20 Pas domain s-box - - - 0.00000000006643 74.0
CSH1_k127_4948368_21 PFAM CBS domain K04767 - - 0.00000006154 56.0
CSH1_k127_4948368_22 - - - - 0.00001486 57.0
CSH1_k127_4948368_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 309.0
CSH1_k127_4948368_4 protein kinase activity K06915 - - 0.000000000000000000000000000000000000000000000000000000000000009379 218.0
CSH1_k127_4948368_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K06987,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000007595 230.0
CSH1_k127_4948368_6 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000000000000000000008239 203.0
CSH1_k127_4948368_7 Integral membrane sensor signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000001665 216.0
CSH1_k127_4948368_8 Archaeal holliday junction resolvase (hjc) - - - 0.00000000000000000000000000000000000000000000001904 176.0
CSH1_k127_4948368_9 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000001934 169.0
CSH1_k127_4951945_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 361.0
CSH1_k127_4951945_1 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000002589 237.0
CSH1_k127_4951945_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000481 160.0
CSH1_k127_4951945_3 Acetyltransferase (GNAT) domain K03823 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 0.00000000000000000000000000000000003453 140.0
CSH1_k127_4951945_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000001695 147.0
CSH1_k127_4951945_5 FG-GAP repeat - - - 0.0000000000000000000000000000006243 126.0
CSH1_k127_4951945_6 PKD domain - - - 0.0000000000001763 85.0
CSH1_k127_4958309_0 by modhmm K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 308.0
CSH1_k127_4958309_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000005646 212.0
CSH1_k127_4958309_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000004609 76.0
CSH1_k127_4976349_0 helicase activity - - - 2.949e-214 682.0
CSH1_k127_4976349_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 287.0
CSH1_k127_4976349_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000006735 179.0
CSH1_k127_5035646_0 Flavin containing amine oxidoreductase K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 592.0
CSH1_k127_5035646_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 552.0
CSH1_k127_5035646_10 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000271 280.0
CSH1_k127_5035646_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000177 267.0
CSH1_k127_5035646_12 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002181 261.0
CSH1_k127_5035646_13 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004492 267.0
CSH1_k127_5035646_14 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000000000000000000000000000000000000000000000000001975 233.0
CSH1_k127_5035646_15 Co Zn Cd efflux system component K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000001441 232.0
CSH1_k127_5035646_16 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000005008 198.0
CSH1_k127_5035646_17 lycopene cyclase - - - 0.0000000000000000000000000000000000000000000000000001571 194.0
CSH1_k127_5035646_18 PFAM Methionine synthase, vitamin-B12 independent K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000000000000000000000000000000000000004361 194.0
CSH1_k127_5035646_19 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000008947 183.0
CSH1_k127_5035646_2 PFAM DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 533.0
CSH1_k127_5035646_20 Ribosomal protein L30p/L7e K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001548 183.0
CSH1_k127_5035646_21 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000004016 190.0
CSH1_k127_5035646_22 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000006319 184.0
CSH1_k127_5035646_23 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000001862 181.0
CSH1_k127_5035646_24 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000001599 170.0
CSH1_k127_5035646_25 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000009704 169.0
CSH1_k127_5035646_26 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001183 170.0
CSH1_k127_5035646_27 Histidine kinase - - - 0.00000000000000000000000000000000000000008255 171.0
CSH1_k127_5035646_28 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000002581 146.0
CSH1_k127_5035646_29 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000004054 145.0
CSH1_k127_5035646_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 467.0
CSH1_k127_5035646_30 Lysine methyltransferase K02493 - 2.1.1.297 0.00000000000000000000000000000000006515 143.0
CSH1_k127_5035646_31 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.00000000000000000000000000000000009284 139.0
CSH1_k127_5035646_32 - - - - 0.000000000000000000000000000001038 130.0
CSH1_k127_5035646_33 Peptidase family M50 - - - 0.0000000000000000000000000002516 123.0
CSH1_k127_5035646_34 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000002105 117.0
CSH1_k127_5035646_35 OB-fold nucleic acid binding domain - - - 0.0000000000000000000000002274 116.0
CSH1_k127_5035646_36 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000006841 110.0
CSH1_k127_5035646_37 Predicted membrane protein (DUF2318) - - - 0.00000000000000000000004004 104.0
CSH1_k127_5035646_38 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000005211 107.0
CSH1_k127_5035646_39 - - - - 0.0000000000000000000003354 104.0
CSH1_k127_5035646_4 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 368.0
CSH1_k127_5035646_40 - - - - 0.0000000000000000001814 92.0
CSH1_k127_5035646_41 ribosomal protein S14 K02954 - - 0.00000000000000000362 84.0
CSH1_k127_5035646_42 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000001653 81.0
CSH1_k127_5035646_43 sequence-specific DNA binding K07108 - - 0.0000000000000871 75.0
CSH1_k127_5035646_44 Pectate lyase - - - 0.000000001887 71.0
CSH1_k127_5035646_45 thymidylate synthase K00560 - 2.1.1.45 0.0000001494 57.0
CSH1_k127_5035646_46 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000001984 53.0
CSH1_k127_5035646_47 protein contain chitin-binding domain type 3 K21606 - 3.2.1.202 0.000006588 59.0
CSH1_k127_5035646_48 membrane - - - 0.0002695 50.0
CSH1_k127_5035646_5 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 347.0
CSH1_k127_5035646_6 COG1549 Queuine tRNA-ribosyltransferases, contain PUA domain K07557 - 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 342.0
CSH1_k127_5035646_7 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 298.0
CSH1_k127_5035646_8 Pheromone shutdown protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 299.0
CSH1_k127_5035646_9 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002476 275.0
CSH1_k127_5037677_0 by modhmm K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 291.0
CSH1_k127_5037677_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000002636 56.0
CSH1_k127_5051902_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.4.2.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 522.0
CSH1_k127_5051902_1 Copper-exporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 497.0
CSH1_k127_5051902_2 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 450.0
CSH1_k127_5051902_3 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 310.0
CSH1_k127_5051902_4 Short C-terminal domain K08982 - - 0.00000000000000000000000000001997 122.0
CSH1_k127_5079132_0 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 352.0
CSH1_k127_5079132_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 359.0
CSH1_k127_5079132_2 arsenite transmembrane transporter activity K03893 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008015 282.0
CSH1_k127_5079132_3 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000003543 169.0
CSH1_k127_5079132_4 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000001771 167.0
CSH1_k127_5079132_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000003166 170.0
CSH1_k127_5079132_6 - - - - 0.0000000000000000000000000000001812 140.0
CSH1_k127_5079132_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0009319 53.0
CSH1_k127_5095284_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1446.0
CSH1_k127_5095284_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.785e-300 931.0
CSH1_k127_5095284_10 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000007101 218.0
CSH1_k127_5095284_11 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000005512 168.0
CSH1_k127_5095284_12 PFAM helix-turn-helix HxlR type - - - 0.000000000000000000000000000000000000002258 149.0
CSH1_k127_5095284_13 - - - - 0.0000000000000000000000000000000001834 140.0
CSH1_k127_5095284_14 Transcriptional regulator K07729 - - 0.000000000000000000000001654 105.0
CSH1_k127_5095284_15 PFAM PKD domain containing protein - - - 0.000000000000000004738 91.0
CSH1_k127_5095284_16 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0007427 42.0
CSH1_k127_5095284_2 Major facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 437.0
CSH1_k127_5095284_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 337.0
CSH1_k127_5095284_4 transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 304.0
CSH1_k127_5095284_5 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005733 272.0
CSH1_k127_5095284_6 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002768 269.0
CSH1_k127_5095284_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000009295 254.0
CSH1_k127_5095284_8 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000001636 232.0
CSH1_k127_5095284_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000005584 228.0
CSH1_k127_5121773_0 bacterial-type flagellum-dependent cell motility K02396,K02397 - - 0.00003881 55.0
CSH1_k127_5228283_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 540.0
CSH1_k127_5228283_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K03918 - 2.6.1.19,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 531.0
CSH1_k127_5228283_10 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000236 276.0
CSH1_k127_5228283_11 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000953 275.0
CSH1_k127_5228283_12 GHMP kinases C terminal K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
CSH1_k127_5228283_13 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002487 263.0
CSH1_k127_5228283_14 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000318 252.0
CSH1_k127_5228283_15 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000009097 228.0
CSH1_k127_5228283_16 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000003254 186.0
CSH1_k127_5228283_17 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.000000000000000000000000000000000000000000000000004026 194.0
CSH1_k127_5228283_18 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.00000000000000000000000000000000000000000003312 173.0
CSH1_k127_5228283_19 Male sterility protein - - - 0.00000000000000000000000000000000000000003323 166.0
CSH1_k127_5228283_2 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 506.0
CSH1_k127_5228283_20 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000004844 149.0
CSH1_k127_5228283_21 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000000000009598 129.0
CSH1_k127_5228283_22 TIGRFAM mutator mutT protein K03574 - 3.6.1.55 0.00000000000000000000000004222 112.0
CSH1_k127_5228283_24 PQ loop repeat K15383 - - 0.000000000000001906 79.0
CSH1_k127_5228283_25 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000007072 76.0
CSH1_k127_5228283_26 Radical SAM - - - 0.000000001045 70.0
CSH1_k127_5228283_27 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000002863 65.0
CSH1_k127_5228283_28 secreted hydrolase - - - 0.00000004376 65.0
CSH1_k127_5228283_29 Nicotianamine synthase protein - - - 0.000005221 56.0
CSH1_k127_5228283_3 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 497.0
CSH1_k127_5228283_4 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 467.0
CSH1_k127_5228283_5 PFAM Citrate lyase, alpha subunit K01643 - 2.8.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 466.0
CSH1_k127_5228283_6 resolution of meiotic recombination intermediates - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 463.0
CSH1_k127_5228283_7 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 343.0
CSH1_k127_5228283_8 TIGRFAM UbiD family decarboxylase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 298.0
CSH1_k127_5228283_9 tRNA pseudouridine synthase D K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002327 284.0
CSH1_k127_5231539_0 calcium- and calmodulin-responsive adenylate cyclase activity K13735,K20276,K21449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000184 252.0
CSH1_k127_5231539_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000001294 247.0
CSH1_k127_5231539_2 COG3420 Nitrous oxidase accessory protein - - - 0.00000006681 64.0
CSH1_k127_5249877_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 375.0
CSH1_k127_5249877_1 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000008305 227.0
CSH1_k127_5249877_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000001048 217.0
CSH1_k127_5267379_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 3.056e-214 678.0
CSH1_k127_5267379_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 452.0
CSH1_k127_5267379_10 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992,K19341 - - 0.0000000000000000000000000000000000000002062 160.0
CSH1_k127_5267379_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002192 148.0
CSH1_k127_5267379_12 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000404 147.0
CSH1_k127_5267379_13 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000001785 135.0
CSH1_k127_5267379_14 Transcriptional regulator - - - 0.000000000000000001995 94.0
CSH1_k127_5267379_15 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000001277 84.0
CSH1_k127_5267379_16 - - - - 0.00000000000001197 79.0
CSH1_k127_5267379_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 301.0
CSH1_k127_5267379_3 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000001067 269.0
CSH1_k127_5267379_4 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001145 259.0
CSH1_k127_5267379_5 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004113 245.0
CSH1_k127_5267379_6 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.0000000000000000000000000000000000000000000000000000000004026 212.0
CSH1_k127_5267379_7 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000001321 214.0
CSH1_k127_5267379_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000006431 174.0
CSH1_k127_5267379_9 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000004906 158.0
CSH1_k127_5299834_0 Peptidase family M28 - - - 0.0000000000000000000000000003143 129.0
CSH1_k127_5299834_1 histidine kinase HAMP region domain protein K03406 - - 0.00003433 48.0
CSH1_k127_5299834_2 regulation of response to stimulus K13730 - - 0.00003747 55.0
CSH1_k127_5302086_0 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000004305 128.0
CSH1_k127_5302086_1 Periplasmic copper-binding protein (NosD) - - - 0.00000000001384 78.0
CSH1_k127_5302086_2 oxidoreductase activity K07114,K12511 - - 0.0000000695 64.0
CSH1_k127_5302086_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000695 64.0
CSH1_k127_5302086_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000001292 65.0
CSH1_k127_5327719_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 6.112e-239 745.0
CSH1_k127_5327719_1 PFAM AMP-dependent synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 569.0
CSH1_k127_5327719_10 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000001588 166.0
CSH1_k127_5327719_11 TraB family - - - 0.000000000000000000000000000000000004841 146.0
CSH1_k127_5327719_12 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.0000000000000000000000000000000001393 151.0
CSH1_k127_5327719_13 Papain family cysteine protease K11751,K14647 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000005237 130.0
CSH1_k127_5327719_14 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000007282 113.0
CSH1_k127_5327719_15 metallopeptidase activity K01181,K05994 - 3.2.1.8,3.4.11.10 0.0000000000000000000001742 113.0
CSH1_k127_5327719_16 PQQ-like domain - - - 0.000000000000000007509 98.0
CSH1_k127_5327719_17 COG3420 Nitrous oxidase accessory protein K07218 - - 0.000000000000001051 89.0
CSH1_k127_5327719_18 Periplasmic copper-binding protein (NosD) - - - 0.00000000000001569 87.0
CSH1_k127_5327719_19 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000002452 86.0
CSH1_k127_5327719_2 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 464.0
CSH1_k127_5327719_20 cell wall organization - - - 0.000000000000115 84.0
CSH1_k127_5327719_21 cell wall organization - - - 0.0000000000004247 81.0
CSH1_k127_5327719_22 PFAM UspA domain protein - - - 0.000000000005943 71.0
CSH1_k127_5327719_23 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000002008 74.0
CSH1_k127_5327719_24 Transglutaminase/protease-like homologues - - - 0.0000000003602 70.0
CSH1_k127_5327719_25 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000006119 72.0
CSH1_k127_5327719_26 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000001216 67.0
CSH1_k127_5327719_27 - - - - 0.000005307 51.0
CSH1_k127_5327719_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 462.0
CSH1_k127_5327719_4 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 421.0
CSH1_k127_5327719_5 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000001942 246.0
CSH1_k127_5327719_6 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002328 225.0
CSH1_k127_5327719_7 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000004921 207.0
CSH1_k127_5327719_8 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000001037 187.0
CSH1_k127_5327719_9 amino acid activation for nonribosomal peptide biosynthetic process K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000005314 198.0
CSH1_k127_5328138_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1142.0
CSH1_k127_5328138_1 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 3.224e-265 846.0
CSH1_k127_5328138_2 PFAM Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000001854 190.0
CSH1_k127_5341692_0 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.000000000000000000000000000000000005274 155.0
CSH1_k127_5433985_0 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000008072 93.0
CSH1_k127_5433985_1 integral membrane protein - - - 0.0000000000000004584 91.0
CSH1_k127_5433985_2 PFAM Peptidase C1A, papain - - - 0.000000000000001656 89.0
CSH1_k127_5433985_3 Protein of unknown function (DUF996) - - - 0.000000000000474 77.0
CSH1_k127_5433985_4 GxGYxYP putative glycoside hydrolase C-terminal domain K03088 - - 0.000007469 58.0
CSH1_k127_5433985_5 Flavodoxin K03809 - 1.6.5.2 0.00009713 50.0
CSH1_k127_5450320_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1099.0
CSH1_k127_5450320_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.92e-234 738.0
CSH1_k127_5450320_10 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 308.0
CSH1_k127_5450320_11 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002084 286.0
CSH1_k127_5450320_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000006667 247.0
CSH1_k127_5450320_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000013 230.0
CSH1_k127_5450320_14 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000003168 233.0
CSH1_k127_5450320_15 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000001182 226.0
CSH1_k127_5450320_16 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000003992 217.0
CSH1_k127_5450320_17 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.00000000000000000000000000000000000000000000000000000000003011 208.0
CSH1_k127_5450320_18 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000001258 194.0
CSH1_k127_5450320_19 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000002136 178.0
CSH1_k127_5450320_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.591e-226 709.0
CSH1_k127_5450320_20 SIS domain K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000313 147.0
CSH1_k127_5450320_21 Lysine exporter protein LysE YggA - - - 0.0000000000000000000000000000000000007985 148.0
CSH1_k127_5450320_22 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000003562 139.0
CSH1_k127_5450320_23 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000007059 103.0
CSH1_k127_5450320_24 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000009752 108.0
CSH1_k127_5450320_25 Uncharacterised protein family (UPF0147) K09721 - - 0.00000000000000000000001967 101.0
CSH1_k127_5450320_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000008401 96.0
CSH1_k127_5450320_27 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000002889 93.0
CSH1_k127_5450320_28 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K22160 - 1.5.98.3 0.000000000000000001282 91.0
CSH1_k127_5450320_29 hydrogenase maturation protease HycI K08315 - 3.4.23.51 0.000000000000000002199 91.0
CSH1_k127_5450320_3 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.398e-209 666.0
CSH1_k127_5450320_30 parallel beta-helix repeat K03671 - - 0.0000000000000000168 94.0
CSH1_k127_5450320_31 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000001176 73.0
CSH1_k127_5450320_32 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000002729 74.0
CSH1_k127_5450320_33 Conserved repeat domain - - - 0.000000001062 71.0
CSH1_k127_5450320_35 self proteolysis - - - 0.000009308 58.0
CSH1_k127_5450320_4 helicase superfamily c-terminal domain K10896 - - 1.291e-205 664.0
CSH1_k127_5450320_5 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 452.0
CSH1_k127_5450320_6 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 403.0
CSH1_k127_5450320_7 NADH ubiquinone oxidoreductase subunit 1 (Chain H) K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 331.0
CSH1_k127_5450320_8 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 337.0
CSH1_k127_5450320_9 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009067 324.0
CSH1_k127_5475080_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 3.051e-301 945.0
CSH1_k127_5475080_1 KH, type 1, domain K07041 - - 1.571e-260 816.0
CSH1_k127_5475080_10 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 367.0
CSH1_k127_5475080_11 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 299.0
CSH1_k127_5475080_12 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 306.0
CSH1_k127_5475080_13 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002805 286.0
CSH1_k127_5475080_14 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006865 274.0
CSH1_k127_5475080_15 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000207 241.0
CSH1_k127_5475080_16 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000001282 205.0
CSH1_k127_5475080_17 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000162 205.0
CSH1_k127_5475080_18 cyclohydrolase K01746 - 4.3.1.4 0.0000000000000000000000000000000000000000000000000001426 192.0
CSH1_k127_5475080_19 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000003865 159.0
CSH1_k127_5475080_2 helicase superfamily c-terminal domain K03724 - - 7.72e-256 819.0
CSH1_k127_5475080_20 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000001163 108.0
CSH1_k127_5475080_21 Domain of unknown function (DUF2341) - - - 0.0000000000004299 81.0
CSH1_k127_5475080_22 - - - - 0.000000004104 62.0
CSH1_k127_5475080_23 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00008529 48.0
CSH1_k127_5475080_3 FMN binding - - - 6.239e-244 763.0
CSH1_k127_5475080_4 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 560.0
CSH1_k127_5475080_5 Proprotein convertase P-domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 571.0
CSH1_k127_5475080_6 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 486.0
CSH1_k127_5475080_7 pyridoxal phosphate-dependent acyltransferase K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 445.0
CSH1_k127_5475080_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 417.0
CSH1_k127_5475080_9 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 399.0
CSH1_k127_5486266_0 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000002676 168.0
CSH1_k127_5486266_1 Copper binding proteins, plastocyanin/azurin family - - - 0.000000007373 68.0
CSH1_k127_5486266_2 Pectinesterase K01051 - 3.1.1.11 0.0003157 46.0
CSH1_k127_5495403_0 COG0058 Glucan phosphorylase - - - 1.701e-223 706.0
CSH1_k127_5495403_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 495.0
CSH1_k127_5495403_10 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008037 295.0
CSH1_k127_5495403_11 COG1691 NCAIR mutase (PurE)-related K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 290.0
CSH1_k127_5495403_12 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001354 287.0
CSH1_k127_5495403_13 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002113 266.0
CSH1_k127_5495403_14 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000321 265.0
CSH1_k127_5495403_15 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003856 258.0
CSH1_k127_5495403_16 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000001698 248.0
CSH1_k127_5495403_17 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000000000000000001049 253.0
CSH1_k127_5495403_18 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008478 256.0
CSH1_k127_5495403_19 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000009748 239.0
CSH1_k127_5495403_2 peptidyl-lysine modification to peptidyl-hypusine K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 465.0
CSH1_k127_5495403_20 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000001674 252.0
CSH1_k127_5495403_21 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000002925 217.0
CSH1_k127_5495403_22 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000000000000000000003974 204.0
CSH1_k127_5495403_23 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000001048 198.0
CSH1_k127_5495403_24 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000006131 195.0
CSH1_k127_5495403_25 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000000000000000000000000000000000000000000462 191.0
CSH1_k127_5495403_26 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000001561 168.0
CSH1_k127_5495403_27 Glycogen debranching enzyme N terminal - - - 0.0000000000000000000000000000000000000000001335 164.0
CSH1_k127_5495403_28 RNA-binding protein of the translin family K07477 - - 0.00000000000000000000000000000000000001016 154.0
CSH1_k127_5495403_29 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000000001881 153.0
CSH1_k127_5495403_3 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 467.0
CSH1_k127_5495403_30 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.00000000000000000000000000000000004425 144.0
CSH1_k127_5495403_31 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00000000000000000000000000000000455 132.0
CSH1_k127_5495403_32 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000137 128.0
CSH1_k127_5495403_33 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000246 102.0
CSH1_k127_5495403_34 PFAM Peptidase C1A, papain - - - 0.0000000000000000767 95.0
CSH1_k127_5495403_35 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000001243 91.0
CSH1_k127_5495403_36 cluster protein-associated redox disulfide domain - - - 0.00000000000004272 76.0
CSH1_k127_5495403_37 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000001119 80.0
CSH1_k127_5495403_38 helix_turn_helix ASNC type - - - 0.00000001655 66.0
CSH1_k127_5495403_39 Peptidase family C25 - - - 0.000001104 61.0
CSH1_k127_5495403_4 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 456.0
CSH1_k127_5495403_40 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000001735 54.0
CSH1_k127_5495403_41 - - - - 0.00003552 53.0
CSH1_k127_5495403_42 acid phosphatase activity - - - 0.00005168 56.0
CSH1_k127_5495403_43 helix_turn_helix ASNC type K03719 - - 0.0001824 51.0
CSH1_k127_5495403_44 domain, Protein K12287,K12548 - - 0.0004509 46.0
CSH1_k127_5495403_5 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 432.0
CSH1_k127_5495403_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 373.0
CSH1_k127_5495403_7 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 353.0
CSH1_k127_5495403_8 Clp protease K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 332.0
CSH1_k127_5495403_9 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 314.0
CSH1_k127_5600181_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 7.356e-226 715.0
CSH1_k127_5600181_1 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 464.0
CSH1_k127_5600181_10 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.0000000000000000000000000004576 117.0
CSH1_k127_5600181_11 Fic/DOC family - - - 0.00000000000000000000007789 109.0
CSH1_k127_5600181_12 Cold shock protein K03704 - - 0.0000000000000000005752 87.0
CSH1_k127_5600181_13 Protease prsW family - - - 0.000000000000000004398 93.0
CSH1_k127_5600181_14 Zn-ribbon containing protein K07163 - - 0.00000000000000003919 88.0
CSH1_k127_5600181_15 acid phosphatase activity K22390 - - 0.0000000004169 73.0
CSH1_k127_5600181_16 cytotoxic translational repressor of toxin-antitoxin K06218 - - 0.000001704 52.0
CSH1_k127_5600181_17 - - - - 0.0000402 49.0
CSH1_k127_5600181_18 Domain of unknown function (DUF4430) - - - 0.0002994 52.0
CSH1_k127_5600181_2 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 372.0
CSH1_k127_5600181_3 Putative exonuclease SbcCD, C subunit K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 320.0
CSH1_k127_5600181_4 GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 297.0
CSH1_k127_5600181_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000000000000002351 251.0
CSH1_k127_5600181_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000004424 209.0
CSH1_k127_5600181_7 - - - - 0.00000000000000000000000000000000000000000000000000004971 194.0
CSH1_k127_5600181_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000000001567 160.0
CSH1_k127_5600181_9 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000001325 130.0
CSH1_k127_5677647_0 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000001619 223.0
CSH1_k127_5677647_1 Psort location Cytoplasmic, score K06934 - - 0.0000000000000000000000000000000000000000000004132 170.0
CSH1_k127_5677647_2 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.000000001578 71.0
CSH1_k127_5677647_3 PFAM PKD domain containing protein - - - 0.00000004179 66.0
CSH1_k127_5677647_4 helix_turn_helix ASNC type K05800 - - 0.0002483 50.0
CSH1_k127_5677647_5 transcriptional regulator K05800 - - 0.0002804 50.0
CSH1_k127_5799211_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006013 286.0
CSH1_k127_5799211_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006436 281.0
CSH1_k127_5799211_2 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000001961 178.0
CSH1_k127_5799211_3 LVIVD repeat-containing protein - - - 0.000000000000000000000001811 123.0
CSH1_k127_5799211_4 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.00000026 66.0
CSH1_k127_5799211_5 Fibronectin type 3 domain - - - 0.00001592 60.0
CSH1_k127_5814719_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 407.0
CSH1_k127_5814719_1 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 411.0
CSH1_k127_5814719_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000001708 61.0
CSH1_k127_5814719_12 SCP-2 sterol transfer family - - - 0.0003772 48.0
CSH1_k127_5814719_2 Sodium:solute symporter family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 374.0
CSH1_k127_5814719_3 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 357.0
CSH1_k127_5814719_4 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000002639 174.0
CSH1_k127_5814719_5 redox-active disulfide protein 2 - - - 0.0000000000000000000004183 97.0
CSH1_k127_5814719_6 PFAM regulatory protein, ArsR K03892,K21903 - - 0.0000000000000004479 80.0
CSH1_k127_5814719_7 PFAM Peptidase C1A, papain - - - 0.00000000000001484 86.0
CSH1_k127_5814719_8 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000001053 74.0
CSH1_k127_5814719_9 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000004794 64.0
CSH1_k127_58206_0 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003103 243.0
CSH1_k127_58206_1 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000001506 184.0
CSH1_k127_58206_10 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0002731 53.0
CSH1_k127_58206_11 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0005037 51.0
CSH1_k127_58206_2 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000008811 174.0
CSH1_k127_58206_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000001238 153.0
CSH1_k127_58206_4 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000002706 117.0
CSH1_k127_58206_5 Methyltransferase domain protein - - - 0.0000000000000000000001485 105.0
CSH1_k127_58206_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000004304 88.0
CSH1_k127_58206_7 Hexapeptide repeat of succinyl-transferase - - - 0.000000000001172 77.0
CSH1_k127_58206_8 deoxyribonucleoside 5'-monophosphate N-glycosidase activity K09457 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 1.7.1.13 0.0000002897 59.0
CSH1_k127_58206_9 Domain of unknown function (DU1801) - - - 0.000000578 56.0
CSH1_k127_5843767_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000001727 241.0
CSH1_k127_5866564_0 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 606.0
CSH1_k127_5866564_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 472.0
CSH1_k127_5866564_10 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 335.0
CSH1_k127_5866564_11 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000001731 185.0
CSH1_k127_5866564_12 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002405 146.0
CSH1_k127_5866564_13 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000001501 89.0
CSH1_k127_5866564_14 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002142 74.0
CSH1_k127_5866564_15 Laminin G domain - - - 0.000000000009024 79.0
CSH1_k127_5866564_16 Uncharacterised protein family (UPF0227) K07000 GO:0003674,GO:0003824,GO:0016787,GO:0016788 - 0.0000001623 61.0
CSH1_k127_5866564_17 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0001565 52.0
CSH1_k127_5866564_2 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 477.0
CSH1_k127_5866564_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 413.0
CSH1_k127_5866564_4 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 407.0
CSH1_k127_5866564_5 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009778 398.0
CSH1_k127_5866564_6 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 381.0
CSH1_k127_5866564_7 nitrogen compound transport K02033,K12369 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 378.0
CSH1_k127_5866564_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 368.0
CSH1_k127_5866564_9 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 337.0
CSH1_k127_5933957_0 addiction module toxin, RelE StbE family - - - 0.00000000000000000000000001873 110.0
CSH1_k127_5933957_1 Protein of unknown function (DUF2683) - - - 0.00000000000000000000004305 101.0
CSH1_k127_5933957_2 - - - - 0.000000000000000000255 90.0
CSH1_k127_5933957_3 Belongs to the UPF0758 family K03630 - - 0.000000000000008188 78.0
CSH1_k127_5933957_4 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000001859 62.0
CSH1_k127_612144_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1120.0
CSH1_k127_612144_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 446.0
CSH1_k127_612144_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000725 55.0
CSH1_k127_612144_2 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 330.0
CSH1_k127_612144_3 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000000000000000001441 238.0
CSH1_k127_612144_4 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000009504 224.0
CSH1_k127_612144_5 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000000001311 199.0
CSH1_k127_612144_6 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.00000000000000000000000000000000000000000000002102 178.0
CSH1_k127_612144_7 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000000000000002197 147.0
CSH1_k127_612144_8 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000003704 87.0
CSH1_k127_612144_9 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.00000003044 65.0
CSH1_k127_631456_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 526.0
CSH1_k127_631456_1 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 342.0
CSH1_k127_707517_0 Phenylalanyl-tRNA synthetase beta K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 308.0
CSH1_k127_707517_1 Parallel beta-helix repeats - - - 0.00000000005145 76.0
CSH1_k127_753523_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1585.0
CSH1_k127_753523_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 590.0
CSH1_k127_753523_10 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000125 227.0
CSH1_k127_753523_11 PFAM HD domain K03698 - - 0.0000000000000000000000000000000000000000000000000000000000007258 224.0
CSH1_k127_753523_12 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000000000000000009327 205.0
CSH1_k127_753523_13 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.0000000000000000000000000000000000000000000000000007662 190.0
CSH1_k127_753523_14 Belongs to the archaeal adenylate kinase family K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000001567 188.0
CSH1_k127_753523_15 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000000000000000000003886 180.0
CSH1_k127_753523_16 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000009034 169.0
CSH1_k127_753523_17 SMART AAA ATPase K07331 - - 0.00000000000000000000000000000000006783 140.0
CSH1_k127_753523_18 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000006631 139.0
CSH1_k127_753523_19 ArsR transcriptional regulator - - - 0.00000000000000000000000000000001074 133.0
CSH1_k127_753523_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 556.0
CSH1_k127_753523_20 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000000000000001414 128.0
CSH1_k127_753523_21 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000004793 114.0
CSH1_k127_753523_22 Integral membrane protein DUF106 - - - 0.000000000000000000000001781 111.0
CSH1_k127_753523_23 binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000003391 103.0
CSH1_k127_753523_24 flagella protein K07327,K07328 - - 0.0000000000000000000007711 105.0
CSH1_k127_753523_25 Archaebacterial flagellin K07330 - - 0.00000000000000000133 91.0
CSH1_k127_753523_26 - - - - 0.00000000000000004049 83.0
CSH1_k127_753523_27 - - - - 0.000000000000008397 83.0
CSH1_k127_753523_28 Belongs to the UPF0434 family - - - 0.000000000000009713 76.0
CSH1_k127_753523_29 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000002491 70.0
CSH1_k127_753523_3 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 534.0
CSH1_k127_753523_30 Archaeal flagellar protein F K07329 - - 0.0000000005677 65.0
CSH1_k127_753523_31 - - - - 0.00000003896 67.0
CSH1_k127_753523_32 PFAM Flagella accessory C family protein K07822 - - 0.00001111 56.0
CSH1_k127_753523_33 N-terminal 7TM region of histidine kinase - - - 0.00002226 57.0
CSH1_k127_753523_34 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00009655 52.0
CSH1_k127_753523_4 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 447.0
CSH1_k127_753523_5 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 369.0
CSH1_k127_753523_6 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 369.0
CSH1_k127_753523_7 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 293.0
CSH1_k127_753523_8 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002368 227.0
CSH1_k127_753523_9 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000006861 231.0
CSH1_k127_753752_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 6.831e-217 698.0
CSH1_k127_753752_1 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 5.764e-196 622.0
CSH1_k127_753752_10 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 366.0
CSH1_k127_753752_11 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 360.0
CSH1_k127_753752_12 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 355.0
CSH1_k127_753752_13 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036,K02068,K06857 - 3.6.3.27,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 317.0
CSH1_k127_753752_14 ABC-type phosphate transport system, periplasmic component K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 301.0
CSH1_k127_753752_15 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 295.0
CSH1_k127_753752_16 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003025 276.0
CSH1_k127_753752_17 Diphthamide K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004377 278.0
CSH1_k127_753752_18 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000002273 267.0
CSH1_k127_753752_19 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001654 261.0
CSH1_k127_753752_2 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 574.0
CSH1_k127_753752_20 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002427 254.0
CSH1_k127_753752_21 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003939 259.0
CSH1_k127_753752_22 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002847 250.0
CSH1_k127_753752_23 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004408 246.0
CSH1_k127_753752_24 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008716 241.0
CSH1_k127_753752_25 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000002349 226.0
CSH1_k127_753752_26 BioY protein K03523 - - 0.0000000000000000000000000000000000000000000000000000000000000003923 228.0
CSH1_k127_753752_27 PFAM Histone deacetylase K04768 - - 0.000000000000000000000000000000000000000000000000000000000000001835 231.0
CSH1_k127_753752_28 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000002396 211.0
CSH1_k127_753752_29 - - - - 0.000000000000000000000000000000000000000000000000000000006803 208.0
CSH1_k127_753752_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 533.0
CSH1_k127_753752_30 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000005895 191.0
CSH1_k127_753752_31 DNA repair and recombination protein RadB K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000001164 178.0
CSH1_k127_753752_32 Evidence 5 No homology to any previously reported sequences K01361,K13277 - 3.4.21.96 0.0000000000000000000000000000000000000000000001303 184.0
CSH1_k127_753752_33 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000009504 161.0
CSH1_k127_753752_34 Protein of unknown function (DUF401) K09133 - - 0.0000000000000000000000000000000000000001699 166.0
CSH1_k127_753752_35 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001048 145.0
CSH1_k127_753752_36 Binds to the 23S rRNA K02929 - - 0.000000000000000000000000000000000003391 140.0
CSH1_k127_753752_37 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000002883 139.0
CSH1_k127_753752_38 PIN domain of ribonuclease K07060 - - 0.0000000000000000000000000008425 119.0
CSH1_k127_753752_39 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000001496 123.0
CSH1_k127_753752_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 470.0
CSH1_k127_753752_40 Hydrogenase maturation protease K03605 - - 0.000000000000000000000001267 108.0
CSH1_k127_753752_41 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000003369 101.0
CSH1_k127_753752_42 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000000008817 109.0
CSH1_k127_753752_43 Aminotransferase - - - 0.000000000000000000001923 108.0
CSH1_k127_753752_44 Ribosomal protein L23 K02892 - - 0.000000000000000003227 89.0
CSH1_k127_753752_45 - - - - 0.000000000000000008698 93.0
CSH1_k127_753752_46 Ribosomal L29 protein K02904 - - 0.00000000000000003935 82.0
CSH1_k127_753752_47 PFAM Ribosomal protein S27E K02978 - - 0.00000000000000017 80.0
CSH1_k127_753752_48 PFAM SMP-30 Gluconolaconase - - - 0.000000000000001188 89.0
CSH1_k127_753752_5 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 419.0
CSH1_k127_753752_50 protein conserved in archaea K09723 - - 0.0000000001295 70.0
CSH1_k127_753752_51 COG2002 Regulators of stationary sporulation gene expression - - - 0.000000001448 60.0
CSH1_k127_753752_52 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000006154 58.0
CSH1_k127_753752_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 401.0
CSH1_k127_753752_7 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 406.0
CSH1_k127_753752_8 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 382.0
CSH1_k127_753752_9 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 368.0
CSH1_k127_756623_0 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000001146 196.0
CSH1_k127_756623_1 Belongs to the peptidase S8 family - - - 0.00000000003867 75.0
CSH1_k127_756623_2 Belongs to the peptidase S8 family K13276,K17734 - - 0.000000002863 58.0
CSH1_k127_764429_0 ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues K01648 GO:0000166,GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003878,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006066,GO:0006082,GO:0006084,GO:0006085,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009893,GO:0009987,GO:0012505,GO:0015936,GO:0016020,GO:0016053,GO:0016125,GO:0016126,GO:0016192,GO:0016740,GO:0016746,GO:0016999,GO:0017076,GO:0017144,GO:0018130,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030141,GO:0030554,GO:0031323,GO:0031325,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032940,GO:0032991,GO:0033500,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0034774,GO:0035337,GO:0035383,GO:0035384,GO:0035578,GO:0035639,GO:0036094,GO:0036230,GO:0042119,GO:0042582,GO:0042592,GO:0042593,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046165,GO:0046390,GO:0046394,GO:0046483,GO:0046903,GO:0046912,GO:0046949,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0055086,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901568,GO:1901570,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653,GO:1904813 2.3.3.8 6.773e-253 794.0
CSH1_k127_764429_1 ATP citrate synthase activity K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 542.0
CSH1_k127_764429_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000441 257.0
CSH1_k127_768759_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000007198 103.0
CSH1_k127_776146_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 4.498e-200 634.0
CSH1_k127_776146_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 592.0
CSH1_k127_776146_10 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000009133 175.0
CSH1_k127_776146_11 Evidence 5 No homology to any previously reported sequences K01361,K13277 - 3.4.21.96 0.00000000000000000000000000000000000000000007018 176.0
CSH1_k127_776146_12 LVIVD repeat-containing protein - - - 0.000000000000000000000000000001755 141.0
CSH1_k127_776146_13 Domain present in carbohydrate binding proteins and sugar hydrolses - - - 0.000000000000000000003752 107.0
CSH1_k127_776146_14 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000006001 90.0
CSH1_k127_776146_15 toxin activity - - - 0.000000000001112 78.0
CSH1_k127_776146_16 Uncharacterised protein - - - 0.000000000005544 78.0
CSH1_k127_776146_17 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000005559 68.0
CSH1_k127_776146_18 - - - - 0.000000001202 65.0
CSH1_k127_776146_19 Winged helix-turn-helix domain (DUF2582) - - - 0.00000006922 59.0
CSH1_k127_776146_2 PFAM type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 531.0
CSH1_k127_776146_20 PFAM regulatory protein AsnC Lrp family K03718 - - 0.00000008707 60.0
CSH1_k127_776146_21 COG1520 FOG WD40-like repeat - - - 0.000000214 65.0
CSH1_k127_776146_22 Winged helix-turn-helix domain (DUF2582) - - - 0.0000002583 58.0
CSH1_k127_776146_23 metallopeptidase activity K01637 - 4.1.3.1 0.0000003674 64.0
CSH1_k127_776146_24 Winged helix-turn-helix domain (DUF2582) - - - 0.000002145 55.0
CSH1_k127_776146_25 Winged helix-turn-helix domain (DUF2582) - - - 0.000004152 55.0
CSH1_k127_776146_26 - - - - 0.000005323 51.0
CSH1_k127_776146_27 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0002746 48.0
CSH1_k127_776146_3 PFAM type II secretion system protein E K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 501.0
CSH1_k127_776146_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 419.0
CSH1_k127_776146_5 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 400.0
CSH1_k127_776146_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001788 296.0
CSH1_k127_776146_7 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000002246 247.0
CSH1_k127_776146_8 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000005502 187.0
CSH1_k127_776146_9 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000008838 179.0
CSH1_k127_782914_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000002402 124.0
CSH1_k127_782914_1 Sulfotransferase family - - - 0.000000000000002022 79.0
CSH1_k127_782914_2 - - - - 0.0000007855 53.0
CSH1_k127_782914_3 - - - - 0.000005548 51.0
CSH1_k127_820391_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 352.0
CSH1_k127_820391_1 transferase activity, transferring glycosyl groups K01179,K01356,K13735,K21449 - 3.2.1.4,3.4.21.88 0.000000009331 68.0
CSH1_k127_820391_2 helix_turn_helix ASNC type K03719 - - 0.00001511 54.0
CSH1_k127_820391_3 membrane-associated protein domain - - - 0.00001876 55.0
CSH1_k127_826845_0 coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 469.0
CSH1_k127_826845_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 349.0
CSH1_k127_826845_2 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 322.0
CSH1_k127_826845_3 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004337 261.0
CSH1_k127_826845_4 S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 K15450 - 2.1.1.282 0.0000000000000000000000000000000000002225 149.0
CSH1_k127_826845_5 heme transporter activity K08220 GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015232,GO:0015886,GO:0016020,GO:0020037,GO:0022857,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:1901363,GO:1901678 - 0.00000000007836 74.0
CSH1_k127_856_0 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 391.0
CSH1_k127_856_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 284.0
CSH1_k127_856_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000002806 211.0
CSH1_k127_856_3 cellulose binding - - - 0.000000000000000000000001731 119.0
CSH1_k127_856_4 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.00000000000000000001385 107.0
CSH1_k127_856_5 Domain of unknown function (DUF1805) - - - 0.0000000000000000005342 90.0
CSH1_k127_856_6 Iron-containing alcohol dehydrogenase K00100,K19955 GO:0003674,GO:0003824,GO:0004022,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - 0.000000000000000003949 85.0
CSH1_k127_856_7 LacY proton/sugar symporter - - - 0.0000000000000002551 91.0
CSH1_k127_856_8 - - - - 0.0006817 46.0
CSH1_k127_857801_0 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 509.0
CSH1_k127_857801_1 phenylalanine-tRNA ligase activity K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 501.0
CSH1_k127_857801_10 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000003763 198.0
CSH1_k127_857801_11 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000003658 186.0
CSH1_k127_857801_12 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000002276 165.0
CSH1_k127_857801_13 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000001565 154.0
CSH1_k127_857801_14 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000009164 147.0
CSH1_k127_857801_15 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000002829 144.0
CSH1_k127_857801_16 Family of unknown function (DUF438) K09155 - - 0.00000000000000000000000000008979 121.0
CSH1_k127_857801_17 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000004102 106.0
CSH1_k127_857801_18 archaeal coiled-coil protein - - - 0.000000000000000000000004556 113.0
CSH1_k127_857801_19 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000005337 96.0
CSH1_k127_857801_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 484.0
CSH1_k127_857801_20 Protein of unknown function (DUF1614) - - - 0.000000000000000000006419 102.0
CSH1_k127_857801_21 Helix-turn-helix XRE-family like proteins K03627 - - 0.0000000000000000009833 93.0
CSH1_k127_857801_22 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000006626 78.0
CSH1_k127_857801_23 ABC-type uncharacterized transport system - - - 0.000000001504 72.0
CSH1_k127_857801_25 - - - - 0.000006353 50.0
CSH1_k127_857801_26 COG1522 Transcriptional regulators - - - 0.00001254 55.0
CSH1_k127_857801_27 antibiotic catabolic process K01406,K02414,K07004,K13277,K21449 - 3.4.24.40 0.00001262 59.0
CSH1_k127_857801_28 S-layer homology domain - - - 0.00008091 54.0
CSH1_k127_857801_29 Protein of unknown function DUF58 - - - 0.0001316 55.0
CSH1_k127_857801_3 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 451.0
CSH1_k127_857801_4 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 377.0
CSH1_k127_857801_5 glutamine synthetase K01915 GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 344.0
CSH1_k127_857801_6 conserved protein related to pyruvate formate-lyase activating enzyme K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 338.0
CSH1_k127_857801_7 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000006736 261.0
CSH1_k127_857801_8 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007865 250.0
CSH1_k127_857801_9 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000000000000000000000000000004101 203.0
CSH1_k127_87107_0 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 362.0
CSH1_k127_87107_1 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 345.0
CSH1_k127_87107_10 Sterol carrier protein - - - 0.000000000005943 71.0
CSH1_k127_87107_11 Periplasmic copper-binding protein (NosD) - - - 0.0000000002375 72.0
CSH1_k127_87107_12 Bacterial Ig-like domain (group 3) - - - 0.0000001356 64.0
CSH1_k127_87107_13 In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha- aminoadipate (AAA) pathway K06154 - - 0.0000008643 60.0
CSH1_k127_87107_14 COG1522 Transcriptional regulators - - - 0.00001129 57.0
CSH1_k127_87107_2 TIGRFAM PAS sensor protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001215 242.0
CSH1_k127_87107_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000001934 240.0
CSH1_k127_87107_5 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000000000000002478 163.0
CSH1_k127_87107_6 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000004021 135.0
CSH1_k127_87107_7 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000007104 121.0
CSH1_k127_87107_8 PQQ enzyme repeat - - - 0.00000000000000000000000001361 126.0
CSH1_k127_87107_9 phosphorelay signal transduction system K07658 - - 0.00000000000000000000005398 102.0
CSH1_k127_873589_0 PFAM Fibronectin type III domain - - - 0.00000000000000000000005742 117.0
CSH1_k127_873589_1 PKD domain containing protein K01183 - 3.2.1.14 0.0000000000000000005026 104.0
CSH1_k127_873589_2 HYR domain - - - 0.000000000000001924 92.0
CSH1_k127_887257_0 - K03561,K12287 - - 0.00000000000000000000000000003289 135.0
CSH1_k127_904827_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 316.0
CSH1_k127_904827_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000002704 251.0
CSH1_k127_904827_2 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.00000000000000000000000000000000000000000000000000000000001417 218.0
CSH1_k127_904827_3 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000000001672 157.0
CSH1_k127_904827_4 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.00000000000000000000000000000002558 145.0
CSH1_k127_904827_5 - - - - 0.000233 51.0
CSH1_k127_920162_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 2.196e-201 651.0
CSH1_k127_920162_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 430.0
CSH1_k127_920162_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002099 256.0
CSH1_k127_925287_0 amine dehydrogenase activity - - - 0.000000000004183 77.0
CSH1_k127_925287_1 Winged helix-turn-helix DNA-binding - - - 0.00001122 57.0
CSH1_k127_925287_2 Domain of unknown function (DUF4389) - - - 0.00001898 55.0
CSH1_k127_967586_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 398.0
CSH1_k127_967586_1 serine-type endopeptidase inhibitor activity K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 296.0
CSH1_k127_967586_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000003515 179.0
CSH1_k127_967586_3 PFAM Thioredoxin K03671 - - 0.0000000000000000000007743 103.0
CSH1_k127_967586_4 PFAM NHL repeat containing protein - - - 0.00000000000000001049 98.0
CSH1_k127_967586_5 exo-alpha-(2->6)-sialidase activity - - - 0.00000004211 67.0
CSH1_k127_968890_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 335.0
CSH1_k127_968890_1 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001309 251.0
CSH1_k127_968890_10 TIGRFAM DNA polymerase (pol2) K02319 - 2.7.7.7 0.00008397 56.0
CSH1_k127_968890_2 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000255 195.0
CSH1_k127_968890_3 PFAM thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000002329 142.0
CSH1_k127_968890_4 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.000000000000000000000000000000001734 134.0
CSH1_k127_968890_5 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000006271 118.0
CSH1_k127_968890_6 Protein of unknown function (DUF1624) - - - 0.0000000000000000000001019 100.0
CSH1_k127_968890_7 Protein of unknown function (DUF998) - - - 0.0000000000001786 78.0
CSH1_k127_968890_8 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000275 83.0
CSH1_k127_968890_9 - - - - 0.000000000000411 72.0
CSH1_k127_975799_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 599.0
CSH1_k127_975799_1 Iron-containing alcohol dehydrogenase K19955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 428.0
CSH1_k127_975799_2 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000002102 211.0
CSH1_k127_975799_3 Zn_pept - - - 0.000000000000000000000000005826 128.0
CSH1_k127_975799_4 KEOPS complex Cgi121-like subunit K09119 - - 0.00000000000000005296 87.0
CSH1_k127_975799_5 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000002826 81.0
CSH1_k127_975799_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00001138 54.0
CSH1_k127_987692_0 ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues K01648 GO:0000166,GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003878,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006066,GO:0006082,GO:0006084,GO:0006085,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009893,GO:0009987,GO:0012505,GO:0015936,GO:0016020,GO:0016053,GO:0016125,GO:0016126,GO:0016192,GO:0016740,GO:0016746,GO:0016999,GO:0017076,GO:0017144,GO:0018130,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030141,GO:0030554,GO:0031323,GO:0031325,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032940,GO:0032991,GO:0033500,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0034774,GO:0035337,GO:0035383,GO:0035384,GO:0035578,GO:0035639,GO:0036094,GO:0036230,GO:0042119,GO:0042582,GO:0042592,GO:0042593,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046165,GO:0046390,GO:0046394,GO:0046483,GO:0046903,GO:0046912,GO:0046949,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0055086,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901568,GO:1901570,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653,GO:1904813 2.3.3.8 9.711e-210 665.0
CSH1_k127_987692_1 ATP citrate synthase activity K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 548.0
CSH1_k127_987692_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000008968 197.0
CSH1_k127_989748_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 502.0
CSH1_k127_989748_1 Acyl--CoA ligase K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 477.0
CSH1_k127_989748_2 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000002811 198.0
CSH1_k127_989748_3 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000001837 183.0
CSH1_k127_989748_4 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.0000000000000000504 85.0