Overview

ID MAG00595
Name CSH1_bin.26
Sample SMP0013
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Steroidobacterales
Family Steroidobacteraceae
Genus RPQJ01
Species
Assembly information
Completeness (%) 75.59
Contamination (%) 1.68
GC content (%) 68.0
N50 (bp) 15,985
Genome size (bp) 2,833,009

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2536

Gene name Description KEGG GOs EC E-value Score Sequence
CSH1_k127_1011847_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 7.226e-277 863.0
CSH1_k127_1011847_1 ABC transporter transmembrane region K06147,K11085 - - 3.108e-209 667.0
CSH1_k127_1011847_10 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000001049 150.0
CSH1_k127_1011847_11 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000000002817 140.0
CSH1_k127_1011847_12 cyclic nucleotide binding K10914 - - 0.00000000000000000000000003296 121.0
CSH1_k127_1011847_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000005058 102.0
CSH1_k127_1011847_14 Transcription factor zinc-finger K09981 - - 0.000005772 51.0
CSH1_k127_1011847_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 517.0
CSH1_k127_1011847_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 524.0
CSH1_k127_1011847_4 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 493.0
CSH1_k127_1011847_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 478.0
CSH1_k127_1011847_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 450.0
CSH1_k127_1011847_7 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 GO:0003674,GO:0003824,GO:0004321,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0071944 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 473.0
CSH1_k127_1011847_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 320.0
CSH1_k127_1011847_9 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 300.0
CSH1_k127_102507_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 2.857e-217 689.0
CSH1_k127_102507_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 426.0
CSH1_k127_102507_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003536 261.0
CSH1_k127_10693_0 Dehydratase family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 471.0
CSH1_k127_10693_1 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 460.0
CSH1_k127_10693_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 445.0
CSH1_k127_10693_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 348.0
CSH1_k127_10693_4 - - - - 0.00000000000000000000000000000000000008195 163.0
CSH1_k127_1100368_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K15022 - 1.17.1.10 1.189e-280 876.0
CSH1_k127_1100368_1 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - 1.261e-267 839.0
CSH1_k127_1100368_10 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 355.0
CSH1_k127_1100368_11 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 322.0
CSH1_k127_1100368_12 ABC transporter K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 293.0
CSH1_k127_1100368_13 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000134 225.0
CSH1_k127_1100368_14 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000002464 207.0
CSH1_k127_1100368_15 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.000000000000000000000000000000000000000000000000653 184.0
CSH1_k127_1100368_16 NUDIX domain - - - 0.0000000000000000000000000000000000000000000002102 171.0
CSH1_k127_1100368_17 - - - - 0.000000000000000000000000000000000000000000005419 173.0
CSH1_k127_1100368_18 lipid kinase, YegS Rv2252 BmrU family - - - 0.00000000000000000000000000000000000001511 163.0
CSH1_k127_1100368_19 protein conserved in bacteria K09796 - - 0.0000000000000000000000003995 112.0
CSH1_k127_1100368_2 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 2.897e-254 822.0
CSH1_k127_1100368_20 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000244 107.0
CSH1_k127_1100368_21 Spore Coat Protein U domain - - - 0.00000000000000000004049 96.0
CSH1_k127_1100368_22 Spore Coat Protein U domain - - - 0.00000000000000008496 88.0
CSH1_k127_1100368_23 - - - - 0.0000000000001392 78.0
CSH1_k127_1100368_24 helix_turn_helix, Lux Regulon - - - 0.000000001174 69.0
CSH1_k127_1100368_25 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000003017 59.0
CSH1_k127_1100368_26 Polyhydroxyalkanoate granule-associated protein - - - 0.000002471 56.0
CSH1_k127_1100368_27 Domain of unknown function (DUF4124) - - - 0.0009263 49.0
CSH1_k127_1100368_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 1.729e-231 734.0
CSH1_k127_1100368_4 FtsX-like permease family K02004 - - 8.197e-221 721.0
CSH1_k127_1100368_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 472.0
CSH1_k127_1100368_6 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 481.0
CSH1_k127_1100368_7 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 417.0
CSH1_k127_1100368_8 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 402.0
CSH1_k127_1100368_9 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 421.0
CSH1_k127_1129229_0 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 452.0
CSH1_k127_1129229_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 392.0
CSH1_k127_1129229_2 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000001719 264.0
CSH1_k127_1129229_3 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000008771 229.0
CSH1_k127_1129229_4 NERD domain protein - - - 0.0000000002456 70.0
CSH1_k127_1132813_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1402.0
CSH1_k127_1132813_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.116e-253 798.0
CSH1_k127_1132813_10 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 345.0
CSH1_k127_1132813_11 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 336.0
CSH1_k127_1132813_12 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 329.0
CSH1_k127_1132813_13 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003617 292.0
CSH1_k127_1132813_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000001378 265.0
CSH1_k127_1132813_15 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000008713 259.0
CSH1_k127_1132813_16 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000007221 260.0
CSH1_k127_1132813_17 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000001072 239.0
CSH1_k127_1132813_18 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000003595 244.0
CSH1_k127_1132813_19 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000005932 221.0
CSH1_k127_1132813_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 8.523e-207 670.0
CSH1_k127_1132813_20 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000006314 225.0
CSH1_k127_1132813_21 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000003637 185.0
CSH1_k127_1132813_22 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000000000000000000005254 186.0
CSH1_k127_1132813_23 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000008088 127.0
CSH1_k127_1132813_24 Belongs to the skp family K06142 - - 0.000000000000000000000000001715 121.0
CSH1_k127_1132813_25 Protein conserved in bacteria - - - 0.000000000000000000000006598 115.0
CSH1_k127_1132813_26 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000004211 96.0
CSH1_k127_1132813_27 - - - - 0.0000000001333 68.0
CSH1_k127_1132813_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 7.122e-194 612.0
CSH1_k127_1132813_4 COG0608 Single-stranded DNA-specific exonuclease K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 571.0
CSH1_k127_1132813_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 458.0
CSH1_k127_1132813_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 451.0
CSH1_k127_1132813_7 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 431.0
CSH1_k127_1132813_8 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 436.0
CSH1_k127_1132813_9 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 378.0
CSH1_k127_1142529_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 0.0 1170.0
CSH1_k127_1142529_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1146.0
CSH1_k127_1142529_10 Peptidase dimerisation domain K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 537.0
CSH1_k127_1142529_11 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 533.0
CSH1_k127_1142529_12 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 518.0
CSH1_k127_1142529_13 Alkaline phosphatase homologues K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 527.0
CSH1_k127_1142529_14 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 518.0
CSH1_k127_1142529_15 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 492.0
CSH1_k127_1142529_16 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 462.0
CSH1_k127_1142529_17 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 423.0
CSH1_k127_1142529_18 von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 403.0
CSH1_k127_1142529_19 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 360.0
CSH1_k127_1142529_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1100.0
CSH1_k127_1142529_20 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 352.0
CSH1_k127_1142529_21 Protein of unknown function (DUF1302) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 351.0
CSH1_k127_1142529_22 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 343.0
CSH1_k127_1142529_23 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 316.0
CSH1_k127_1142529_24 Protease prsW family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 300.0
CSH1_k127_1142529_25 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 292.0
CSH1_k127_1142529_26 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007897 286.0
CSH1_k127_1142529_27 Ornithine cyclodeaminase/mu-crystallin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002232 282.0
CSH1_k127_1142529_28 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006485 265.0
CSH1_k127_1142529_29 Belongs to the long-chain O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007447 278.0
CSH1_k127_1142529_3 AMP-binding enzyme K01897 - 6.2.1.3 7.883e-251 784.0
CSH1_k127_1142529_30 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000004036 263.0
CSH1_k127_1142529_31 IQR COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003656 258.0
CSH1_k127_1142529_32 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000001049 226.0
CSH1_k127_1142529_33 Bacterial PH domain - - - 0.00000000000000000000000000000000000000000000000000000000003451 209.0
CSH1_k127_1142529_34 Flavodoxin domain K00230 GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.3 0.00000000000000000000000000000000000000000000000000000000009394 210.0
CSH1_k127_1142529_35 - - - - 0.0000000000000000000000000000000000000000005018 169.0
CSH1_k127_1142529_36 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000007321 145.0
CSH1_k127_1142529_37 Translation initiation factor 1A / IF-1 K02518 - - 0.000000000000000000000000000000001043 131.0
CSH1_k127_1142529_38 Protein of unknown function (DUF1249) K09920 - - 0.0000000000000000000000000001385 125.0
CSH1_k127_1142529_39 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000001853 118.0
CSH1_k127_1142529_4 Alkyl hydroperoxide reductase K03387 - - 6.277e-244 762.0
CSH1_k127_1142529_40 - - - - 0.00000000000000000000000002344 121.0
CSH1_k127_1142529_41 pyrroloquinoline quinone binding - - - 0.000000000000000000000004487 112.0
CSH1_k127_1142529_42 - - - - 0.000000000000000000000005901 113.0
CSH1_k127_1142529_43 Prokaryotic cytochrome b561 - - - 0.0000000000000000000007986 102.0
CSH1_k127_1142529_44 transcriptional regulator - - - 0.00000000000000000000557 107.0
CSH1_k127_1142529_45 - - - - 0.000000000000006162 81.0
CSH1_k127_1142529_46 - - - - 0.0000000000359 68.0
CSH1_k127_1142529_48 Extracellular repeat protein, HAF family - - - 0.00005999 55.0
CSH1_k127_1142529_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.355e-241 781.0
CSH1_k127_1142529_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 5.233e-195 628.0
CSH1_k127_1142529_7 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 605.0
CSH1_k127_1142529_8 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 550.0
CSH1_k127_1142529_9 IgA Peptidase M64 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 537.0
CSH1_k127_1169801_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 9.497e-264 827.0
CSH1_k127_1169801_1 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.237e-246 767.0
CSH1_k127_1169801_10 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000005079 197.0
CSH1_k127_1169801_11 domain, Protein - - - 0.00000000000000000000000000000000000000000000004038 192.0
CSH1_k127_1169801_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000001342 143.0
CSH1_k127_1169801_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000001645 138.0
CSH1_k127_1169801_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000002481 95.0
CSH1_k127_1169801_15 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000005414 89.0
CSH1_k127_1169801_16 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000004024 64.0
CSH1_k127_1169801_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.77e-246 783.0
CSH1_k127_1169801_3 Sulfate permease family K03321 GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - 2.2e-246 771.0
CSH1_k127_1169801_4 May be involved in recombinational repair of damaged DNA K03631 GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 467.0
CSH1_k127_1169801_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 389.0
CSH1_k127_1169801_6 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 380.0
CSH1_k127_1169801_7 FMN-dependent dehydrogenase K15054 - 1.1.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 366.0
CSH1_k127_1169801_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000003436 254.0
CSH1_k127_1169801_9 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000004757 211.0
CSH1_k127_119317_0 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 510.0
CSH1_k127_119317_1 FAD dependent oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 519.0
CSH1_k127_119317_2 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 508.0
CSH1_k127_119317_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 404.0
CSH1_k127_119317_4 COG1398 Fatty-acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 369.0
CSH1_k127_119317_5 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 319.0
CSH1_k127_119317_6 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000015 150.0
CSH1_k127_119317_7 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000001981 119.0
CSH1_k127_121357_0 Peptidase family M49 - - - 1.263e-219 696.0
CSH1_k127_121357_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 357.0
CSH1_k127_121357_10 Domain of unknown function (DUF4404) - - - 0.000009641 54.0
CSH1_k127_121357_2 Polypeptide deformylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002631 245.0
CSH1_k127_121357_4 Periplasmic Protein K08985 - - 0.00000000000000000000000000001368 128.0
CSH1_k127_121357_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000007636 121.0
CSH1_k127_121357_6 - - - - 0.0000000000000000000002012 101.0
CSH1_k127_121357_7 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000168 102.0
CSH1_k127_121357_8 - - - - 0.0000000000003926 77.0
CSH1_k127_121357_9 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000006256 69.0
CSH1_k127_1243385_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1160.0
CSH1_k127_1243385_1 COG5598 Trimethylamine corrinoid methyltransferase K14083 - 2.1.1.250 6.737e-237 743.0
CSH1_k127_1243385_2 belongs to the aldehyde dehydrogenase family K09472 - 1.2.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 579.0
CSH1_k127_1243385_3 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.000000000000000000889 87.0
CSH1_k127_1243385_4 Belongs to the GcvT family K00315 - 1.5.8.4 0.0000000006841 62.0
CSH1_k127_1310816_0 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 598.0
CSH1_k127_1310816_1 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 467.0
CSH1_k127_1310816_2 Lipocalin-like domain - - - 0.00000000000002526 75.0
CSH1_k127_1315677_0 Belongs to the GcvT family K00315 - 1.5.8.4 0.0 1275.0
CSH1_k127_1315677_1 Outer membrane receptor K02014 - - 2.379e-236 758.0
CSH1_k127_1315677_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 9.368e-214 674.0
CSH1_k127_1315677_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 502.0
CSH1_k127_1315677_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 340.0
CSH1_k127_1315677_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03828 - - 0.000000000000000000000000000000000000000000000000000000000000000005343 228.0
CSH1_k127_1315677_6 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000004237 201.0
CSH1_k127_1315677_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000754 175.0
CSH1_k127_132698_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 3.022e-271 851.0
CSH1_k127_132698_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 401.0
CSH1_k127_132698_2 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000188 224.0
CSH1_k127_132698_3 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000004645 207.0
CSH1_k127_132698_4 HNH nucleases - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000004673 175.0
CSH1_k127_132698_5 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family - - - 0.0000000000000000000002445 103.0
CSH1_k127_132698_6 Bacterial protein of unknown function (DUF883) - - - 0.00000000000000000004142 93.0
CSH1_k127_132698_7 COG0575 CDP-diglyceride synthetase K19664 - 2.7.7.67 0.0000000000000741 78.0
CSH1_k127_132698_8 - - - - 0.0000000000001067 84.0
CSH1_k127_132698_9 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000004149 62.0
CSH1_k127_1369680_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 1.04e-318 990.0
CSH1_k127_1369680_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000165 198.0
CSH1_k127_1369680_2 CRS1_YhbY K07574 - - 0.0000000000000000000000006734 107.0
CSH1_k127_1378705_0 PFAM NADH flavin oxidoreductase NADH oxidase K00317 - 1.5.8.1,1.5.8.2 5e-324 1003.0
CSH1_k127_1378705_1 Prokaryotic glutathione synthetase, ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 4.04e-207 653.0
CSH1_k127_1378705_2 Mur ligase family, glutamate ligase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 535.0
CSH1_k127_1378705_3 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 517.0
CSH1_k127_1378705_4 glucose sorbosone K00117,K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 428.0
CSH1_k127_1439703_0 Nitric oxide reductase large subunit K04561 - 1.7.2.5 0.0 1046.0
CSH1_k127_1439703_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 545.0
CSH1_k127_1439703_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 453.0
CSH1_k127_1439703_3 Nitrite reductase K15864 - 1.7.2.1,1.7.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 430.0
CSH1_k127_1439703_4 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 422.0
CSH1_k127_1439703_5 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 337.0
CSH1_k127_1439703_6 protein involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001562 265.0
CSH1_k127_1439703_7 PFAM Cyclic nucleotide-binding K21563 - - 0.0000000000000000000000000000000000000000000001294 179.0
CSH1_k127_1439703_8 Invasion gene expression up-regulator, SirB - - - 0.000000000000000000000000005037 130.0
CSH1_k127_1439703_9 Cytochrome c K08738 - - 0.00000000000000000005147 95.0
CSH1_k127_1486697_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 1.847e-310 966.0
CSH1_k127_1486697_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.382e-216 685.0
CSH1_k127_1486697_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 445.0
CSH1_k127_1486697_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 377.0
CSH1_k127_1486697_4 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000001296 171.0
CSH1_k127_1486697_5 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.0000000000000000000000000000000000002458 144.0
CSH1_k127_1486697_6 succinate dehydrogenase K00242 - - 0.000000000000000000000001477 113.0
CSH1_k127_1486697_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000004649 83.0
CSH1_k127_1486697_8 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000001374 82.0
CSH1_k127_1486697_9 Protein of unknown function (DUF1674) - - - 0.000000001351 61.0
CSH1_k127_1497282_0 belongs to the aldehyde dehydrogenase family K00138 - - 3.186e-305 938.0
CSH1_k127_1497282_1 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 489.0
CSH1_k127_1497282_10 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000001812 246.0
CSH1_k127_1497282_11 Protein of unknown function (DUF779) K09959 - - 0.00000000000000000000000000000000000000000000000000000000000008126 218.0
CSH1_k127_1497282_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.000000000000000000000000000000000000000000000000000000000002182 222.0
CSH1_k127_1497282_13 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000003324 214.0
CSH1_k127_1497282_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000001592 212.0
CSH1_k127_1497282_15 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000007955 182.0
CSH1_k127_1497282_16 Putative phosphatase (DUF442) - - - 0.00000000000000000000000000000000000000000000000001283 194.0
CSH1_k127_1497282_17 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000006349 178.0
CSH1_k127_1497282_18 Translation initiation factor K03113 - - 0.000000000000000000000000000000000001566 146.0
CSH1_k127_1497282_19 lipid-A-disaccharide synthase activity - - - 0.0000000000000000000000000000004949 127.0
CSH1_k127_1497282_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 492.0
CSH1_k127_1497282_20 Belongs to the UPF0434 family K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000005584 87.0
CSH1_k127_1497282_21 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000001456 76.0
CSH1_k127_1497282_3 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 439.0
CSH1_k127_1497282_4 TIGRFAM ABC exporter ATP-binding subunit, DevA family K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 376.0
CSH1_k127_1497282_5 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 340.0
CSH1_k127_1497282_6 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 348.0
CSH1_k127_1497282_7 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 323.0
CSH1_k127_1497282_8 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 333.0
CSH1_k127_1497282_9 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000005904 261.0
CSH1_k127_1514613_0 small GTP-binding protein K02355 - - 5.384e-290 904.0
CSH1_k127_1514613_1 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 474.0
CSH1_k127_1514613_10 periplasmic protein K09797 - - 0.000000000000000000000000000000000000000004657 165.0
CSH1_k127_1514613_11 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000002601 168.0
CSH1_k127_1514613_12 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - 0.000000000000134 72.0
CSH1_k127_1514613_2 Malic enzyme, N-terminal domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 465.0
CSH1_k127_1514613_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 361.0
CSH1_k127_1514613_4 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 345.0
CSH1_k127_1514613_5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 334.0
CSH1_k127_1514613_6 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 312.0
CSH1_k127_1514613_7 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001894 283.0
CSH1_k127_1514613_8 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004593 243.0
CSH1_k127_1514613_9 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000222 188.0
CSH1_k127_15347_0 Prokaryotic glutathione synthetase, ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 2.348e-276 854.0
CSH1_k127_15347_1 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation K01305 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008270,GO:0008798,GO:0016787,GO:0019538,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 506.0
CSH1_k127_15347_2 transporter K03761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 466.0
CSH1_k127_15347_3 Peptidase family S51 K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 433.0
CSH1_k127_15347_4 Catalyzes the sodium-dependent transport of glutamate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 316.0
CSH1_k127_15347_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 301.0
CSH1_k127_15347_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003289 270.0
CSH1_k127_15347_7 TRAP transporter solute receptor TAXI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001425 266.0
CSH1_k127_1557312_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.595e-243 786.0
CSH1_k127_1557312_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 530.0
CSH1_k127_1557312_10 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000001765 212.0
CSH1_k127_1557312_11 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000004292 216.0
CSH1_k127_1557312_12 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.000000000000000000000000000000000000000000000000000007014 200.0
CSH1_k127_1557312_13 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000001759 179.0
CSH1_k127_1557312_14 PFAM glycosyl transferase family 9 - - - 0.000000000000000000000000000000000000000006655 158.0
CSH1_k127_1557312_15 Belongs to the bacterial histone-like protein family - - - 0.000000000000000000000000000000000001862 142.0
CSH1_k127_1557312_16 Zinc-finger domain - - - 0.00000000000000000000003215 100.0
CSH1_k127_1557312_17 SMART Metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000004746 99.0
CSH1_k127_1557312_18 SlyX protein K03745 - - 0.0005378 48.0
CSH1_k127_1557312_19 - - - - 0.0007193 49.0
CSH1_k127_1557312_2 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 486.0
CSH1_k127_1557312_3 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 421.0
CSH1_k127_1557312_4 COG1519 3-deoxy-D-manno-octulosonic-acid transferase K02527 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 390.0
CSH1_k127_1557312_5 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 291.0
CSH1_k127_1557312_6 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001823 283.0
CSH1_k127_1557312_7 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001746 289.0
CSH1_k127_1557312_8 Major facilitator Superfamily K08162,K08226,K16211 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002387 282.0
CSH1_k127_1557312_9 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001471 260.0
CSH1_k127_1559622_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1018.0
CSH1_k127_1559622_1 PFAM acyl-CoA dehydrogenase domain protein K00248 - 1.3.8.1 8.277e-283 879.0
CSH1_k127_1559622_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 432.0
CSH1_k127_1559622_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799,K18298,K18901,K19586,K19595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 296.0
CSH1_k127_1559622_4 - - - - 0.000000000000000001161 94.0
CSH1_k127_1559785_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 604.0
CSH1_k127_1559785_1 Homospermidine synthase K00808 - 2.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 516.0
CSH1_k127_1559785_2 SMART Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001152 287.0
CSH1_k127_1559785_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000001267 210.0
CSH1_k127_1575603_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1185.0
CSH1_k127_1575603_1 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.0 1175.0
CSH1_k127_1575603_10 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 320.0
CSH1_k127_1575603_11 ABC transporter permease K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001226 266.0
CSH1_k127_1575603_12 TIGRFAM FeS assembly SUF system protein SufT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003744 256.0
CSH1_k127_1575603_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007826 252.0
CSH1_k127_1575603_14 assembly protein SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009875 259.0
CSH1_k127_1575603_15 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000216 243.0
CSH1_k127_1575603_16 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000139 226.0
CSH1_k127_1575603_17 PFAM Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000009915 211.0
CSH1_k127_1575603_18 TIGRFAM SUF system FeS K04488 - - 0.0000000000000000000000000000000000000000000000000000003212 199.0
CSH1_k127_1575603_19 PFAM Amino acid-binding ACT K03567 - - 0.0000000000000000000000000000000000000000000000000000006021 197.0
CSH1_k127_1575603_2 TIGRFAM FeS assembly protein SufB K09014 - - 1.02e-264 823.0
CSH1_k127_1575603_20 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000005642 197.0
CSH1_k127_1575603_21 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000002053 184.0
CSH1_k127_1575603_22 salt-induced outer membrane protein K07283 - - 0.000000000000000000000000000000000000000001308 174.0
CSH1_k127_1575603_23 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000004635 156.0
CSH1_k127_1575603_24 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.000000000000000000000000000000000000001787 162.0
CSH1_k127_1575603_25 transcriptional regulator - - - 0.00000000000000000000000000000000004713 142.0
CSH1_k127_1575603_26 PFAM Phosphoglycerate mutase K08296 - - 0.0000000000000000000000000000000001791 143.0
CSH1_k127_1575603_27 PFAM Rieske 2Fe-2S K05710 - - 0.000000000000000000000000000000004608 130.0
CSH1_k127_1575603_28 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000001436 130.0
CSH1_k127_1575603_29 Phosphoglycerate mutase family - - - 0.0000000000000118 81.0
CSH1_k127_1575603_3 AMP-binding enzyme C-terminal domain K00666 - - 2.906e-261 820.0
CSH1_k127_1575603_30 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000001207 84.0
CSH1_k127_1575603_31 response to antibiotic K07122 - - 0.000000007377 62.0
CSH1_k127_1575603_33 - - - - 0.0001499 45.0
CSH1_k127_1575603_4 SMART Nucleotide binding protein, PINc K07175 - - 1.467e-209 669.0
CSH1_k127_1575603_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 566.0
CSH1_k127_1575603_6 Serine dehydratase beta chain K01752 GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 561.0
CSH1_k127_1575603_7 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 386.0
CSH1_k127_1575603_8 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 345.0
CSH1_k127_1575603_9 PFAM ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 340.0
CSH1_k127_1578249_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1076.0
CSH1_k127_1578249_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.796e-248 783.0
CSH1_k127_1578249_2 transporter, permease K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 387.0
CSH1_k127_1578249_3 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 355.0
CSH1_k127_1578249_4 Belongs to the ABC transporter superfamily K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 316.0
CSH1_k127_1578249_5 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001481 286.0
CSH1_k127_1578249_6 Oligopeptide/dipeptide transporter, C-terminal region K10823 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000663 258.0
CSH1_k127_1578249_7 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.0000000000000000000000000000000000000000000004163 181.0
CSH1_k127_1578249_8 synthesis repressor, PhaR - - - 0.000000000000000000000000000000000001657 147.0
CSH1_k127_1578249_9 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.00000000000000001887 94.0
CSH1_k127_1579534_0 Protein of unknown function (DUF3604) - - - 1.323e-201 658.0
CSH1_k127_1579534_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 599.0
CSH1_k127_1579534_2 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 545.0
CSH1_k127_1579534_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000001765 168.0
CSH1_k127_1579534_5 - - - - 0.0000000000000000000000000000000000000009652 166.0
CSH1_k127_1579534_6 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000001741 163.0
CSH1_k127_1587220_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 336.0
CSH1_k127_1587220_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 317.0
CSH1_k127_1587220_2 Major Facilitator K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001912 279.0
CSH1_k127_1587220_3 PFAM SMP-30 Gluconolaconase - - - 0.000000003758 69.0
CSH1_k127_1596182_0 FAD dependent oxidoreductase K07077 - - 4.777e-210 664.0
CSH1_k127_1596182_1 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 552.0
CSH1_k127_1596182_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 489.0
CSH1_k127_1596182_3 Protein conserved in bacteria K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 479.0
CSH1_k127_1596182_4 dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 291.0
CSH1_k127_1596182_5 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 294.0
CSH1_k127_1596182_6 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000006401 246.0
CSH1_k127_1596182_7 PFAM Exopolysaccharide synthesis ExoD - - - 0.00000000000000000000000000000000000000000001153 170.0
CSH1_k127_1596182_8 - - - - 0.000000000000000000000000000003321 126.0
CSH1_k127_1606629_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 6.589e-293 912.0
CSH1_k127_1606629_1 Penicillin acylase K01434 - 3.5.1.11 1.009e-212 686.0
CSH1_k127_1606629_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 596.0
CSH1_k127_1606629_3 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 546.0
CSH1_k127_1606629_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 516.0
CSH1_k127_1606629_5 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000006232 224.0
CSH1_k127_1606629_6 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000008676 218.0
CSH1_k127_1607136_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 636.0
CSH1_k127_1607136_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 512.0
CSH1_k127_1607136_2 RES - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001049 285.0
CSH1_k127_1607136_3 Protein of unknown function (DUF2384) - - - 0.000000000000000000000000000000000000000004905 157.0
CSH1_k127_1616152_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.06e-236 745.0
CSH1_k127_1616152_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.561e-224 719.0
CSH1_k127_1616152_2 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 542.0
CSH1_k127_1616152_3 Transcriptional regulator K13634 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 377.0
CSH1_k127_1616152_4 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000000000000004246 214.0
CSH1_k127_1616152_5 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.000000000000000000000000000000000000000000008476 169.0
CSH1_k127_1616152_6 Protein of unknown function (DUF3106) - - - 0.00000000000000000000006191 109.0
CSH1_k127_1616152_7 cell division protein - - - 0.00000000000002739 81.0
CSH1_k127_1616152_8 Phosphate-selective porin O and P K07221 - - 0.0002372 48.0
CSH1_k127_1619652_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 6.42e-290 901.0
CSH1_k127_1619652_1 GTP-binding protein TypA K06207 - - 1.129e-284 889.0
CSH1_k127_1619652_10 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001171 262.0
CSH1_k127_1619652_11 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000001088 231.0
CSH1_k127_1619652_12 response regulator K07715 - - 0.0000000000000000000000000000000000000000008581 163.0
CSH1_k127_1619652_13 COG1214 Inactive homolog of metal-dependent proteases K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 - 0.000000000000000000000000000000000000000004525 163.0
CSH1_k127_1619652_14 phosphate regulon transcriptional regulatory protein PhoB K07657 GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000003095 84.0
CSH1_k127_1619652_15 metallopeptidase activity K01179,K20276 - 3.2.1.4 0.00000000000000007793 95.0
CSH1_k127_1619652_16 TIGRFAM conserved repeat domain - - - 0.000000000001144 77.0
CSH1_k127_1619652_2 Helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 627.0
CSH1_k127_1619652_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 641.0
CSH1_k127_1619652_4 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 471.0
CSH1_k127_1619652_5 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 466.0
CSH1_k127_1619652_6 Ecdysteroid kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 409.0
CSH1_k127_1619652_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 404.0
CSH1_k127_1619652_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 381.0
CSH1_k127_1619652_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 348.0
CSH1_k127_164494_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 560.0
CSH1_k127_164494_1 NRAMP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 514.0
CSH1_k127_164494_10 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.000000000000000000000000000000000000001795 160.0
CSH1_k127_164494_11 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000005386 112.0
CSH1_k127_164494_12 LNS2 K15728 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0019374,GO:0019375,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0048046,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.4 0.0005913 44.0
CSH1_k127_164494_2 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 447.0
CSH1_k127_164494_3 DNA mediated transformation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 424.0
CSH1_k127_164494_4 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 345.0
CSH1_k127_164494_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 325.0
CSH1_k127_164494_6 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007489 260.0
CSH1_k127_164494_7 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004258 248.0
CSH1_k127_164494_8 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000002518 238.0
CSH1_k127_164494_9 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000001754 184.0
CSH1_k127_1666600_0 Outer membrane receptor - - - 6.975e-317 994.0
CSH1_k127_1666600_1 COG0457 FOG TPR repeat - - - 1.881e-275 862.0
CSH1_k127_1666600_10 COG0303 Molybdopterin biosynthesis enzyme K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 349.0
CSH1_k127_1666600_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002035 274.0
CSH1_k127_1666600_12 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K05776,K10441,K10539,K10542,K10545,K10548 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000002147 286.0
CSH1_k127_1666600_13 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000001155 252.0
CSH1_k127_1666600_14 Acyl-CoA dehydrogenase N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000002731 242.0
CSH1_k127_1666600_15 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000005951 199.0
CSH1_k127_1666600_16 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000005094 192.0
CSH1_k127_1666600_17 Molybdopterin K03636 - - 0.00000000000000000000001617 104.0
CSH1_k127_1666600_2 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 8.919e-231 730.0
CSH1_k127_1666600_3 TonB-dependent receptor plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 581.0
CSH1_k127_1666600_4 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 572.0
CSH1_k127_1666600_5 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 556.0
CSH1_k127_1666600_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 460.0
CSH1_k127_1666600_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 443.0
CSH1_k127_1666600_8 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 447.0
CSH1_k127_1666600_9 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 440.0
CSH1_k127_1667354_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009256 614.0
CSH1_k127_1667354_1 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 461.0
CSH1_k127_1667354_10 Domain of unknown function (DUF1330) - - - 0.000000000000000000000175 100.0
CSH1_k127_1667354_11 Fic/DOC family K07341 - - 0.000000000000003342 76.0
CSH1_k127_1667354_12 Diguanylate cyclase - - - 0.000000000001739 78.0
CSH1_k127_1667354_13 - - - - 0.00001001 53.0
CSH1_k127_1667354_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 432.0
CSH1_k127_1667354_3 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 362.0
CSH1_k127_1667354_4 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 332.0
CSH1_k127_1667354_5 Mandelate racemase muconate lactonizing enzyme K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 297.0
CSH1_k127_1667354_6 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000002016 204.0
CSH1_k127_1667354_7 Trypsin - - - 0.000000000000000000000000000000000000000000000007796 188.0
CSH1_k127_1667354_8 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000000000000004747 172.0
CSH1_k127_1667354_9 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000001093 128.0
CSH1_k127_1691650_0 glutamate synthase K00284 - 1.4.7.1 0.0 2509.0
CSH1_k127_1691650_1 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 4.694e-257 802.0
CSH1_k127_1691650_2 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.000000000000000000000000000000000000000000000000002772 187.0
CSH1_k127_1699895_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 6.915e-245 789.0
CSH1_k127_1699895_1 Belongs to the glycosyl hydrolase 13 family K21575 - 3.2.1.135 7.08e-210 673.0
CSH1_k127_1699895_2 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 608.0
CSH1_k127_1699895_3 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 559.0
CSH1_k127_1699895_4 4-alpha-glucanotransferase K00705 GO:0000023,GO:0000025,GO:0003674,GO:0003824,GO:0004133,GO:0004134,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005984,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046352,GO:0055114,GO:0071704,GO:1901575 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 394.0
CSH1_k127_1699895_5 Tryptophan halogenase K14266 - 1.14.19.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 289.0
CSH1_k127_1738725_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.212e-228 712.0
CSH1_k127_1738725_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 9.491e-203 640.0
CSH1_k127_1738725_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 451.0
CSH1_k127_1738725_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 410.0
CSH1_k127_1738725_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000004897 250.0
CSH1_k127_1738725_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000002061 130.0
CSH1_k127_1738725_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000007695 81.0
CSH1_k127_1738725_7 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000005755 71.0
CSH1_k127_1763688_0 Belongs to the TPP enzyme family K03852 - 2.3.3.15 1.102e-272 850.0
CSH1_k127_1763688_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.167e-219 717.0
CSH1_k127_1763688_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000001839 228.0
CSH1_k127_1763688_11 methylamine dehydrogenase accessory protein MauD - - - 0.000000000000000000000000000000000000000000000000000000000009652 214.0
CSH1_k127_1763688_12 EcsC protein family - - - 0.0000000000000000000000000000000000000000000000000000003993 200.0
CSH1_k127_1763688_13 - - - - 0.0000000000000000000000000000000000000000000000001204 186.0
CSH1_k127_1763688_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000001015 162.0
CSH1_k127_1763688_15 TfoX N-terminal domain - - - 0.000000000000000000000000000000000453 136.0
CSH1_k127_1763688_17 Cytochrome c - - - 0.00000000000000000000000001868 117.0
CSH1_k127_1763688_18 Methylamine utilisation protein MauE - - - 0.00000000000000000000511 100.0
CSH1_k127_1763688_19 Predicted membrane protein (DUF2157) - - - 0.0000000000000006335 89.0
CSH1_k127_1763688_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 514.0
CSH1_k127_1763688_20 Cytochrome c class I - - - 0.000123 48.0
CSH1_k127_1763688_3 PFAM sodium calcium exchanger membrane region K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 446.0
CSH1_k127_1763688_4 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 362.0
CSH1_k127_1763688_5 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 311.0
CSH1_k127_1763688_6 Methylamine dehydrogenase light chain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003884 263.0
CSH1_k127_1763688_7 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007058 262.0
CSH1_k127_1763688_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001918 257.0
CSH1_k127_1763688_9 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000003552 239.0
CSH1_k127_1788262_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 1.391e-277 884.0
CSH1_k127_1788262_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 484.0
CSH1_k127_1788262_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 469.0
CSH1_k127_1788262_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001121 274.0
CSH1_k127_1788262_4 helix_turn_helix, arabinose operon control protein K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000005001 254.0
CSH1_k127_1788262_5 Dehydratase - - - 0.0000000000000000000000000000000000000000000000007446 179.0
CSH1_k127_1788262_6 synthesis repressor, PhaR - - - 0.0000000000000000000000000000000000003849 150.0
CSH1_k127_1804443_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 2.331e-270 837.0
CSH1_k127_1804443_1 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 4.385e-259 808.0
CSH1_k127_1804443_10 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 551.0
CSH1_k127_1804443_11 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 553.0
CSH1_k127_1804443_12 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 535.0
CSH1_k127_1804443_13 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 494.0
CSH1_k127_1804443_14 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 486.0
CSH1_k127_1804443_15 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 471.0
CSH1_k127_1804443_16 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 440.0
CSH1_k127_1804443_17 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 426.0
CSH1_k127_1804443_18 protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 388.0
CSH1_k127_1804443_19 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 391.0
CSH1_k127_1804443_2 Formyl transferase, C-terminal domain K19640 - - 9.615e-254 803.0
CSH1_k127_1804443_20 Flavin containing amine oxidoreductase K09516,K09835 - 1.3.99.23,5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 376.0
CSH1_k127_1804443_21 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 329.0
CSH1_k127_1804443_22 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 323.0
CSH1_k127_1804443_23 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 319.0
CSH1_k127_1804443_24 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004505 276.0
CSH1_k127_1804443_25 cytochrome c oxidase (Subunit II) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007551 247.0
CSH1_k127_1804443_26 Transcriptional regulator, HxlR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006418 248.0
CSH1_k127_1804443_27 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000003811 234.0
CSH1_k127_1804443_28 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000002654 211.0
CSH1_k127_1804443_29 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000000000000000426 199.0
CSH1_k127_1804443_3 Belongs to the HypD family K04654 - - 4.115e-205 651.0
CSH1_k127_1804443_30 - - - - 0.0000000000000000000000000000000000000000000000000002016 190.0
CSH1_k127_1804443_31 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000000000000000004889 192.0
CSH1_k127_1804443_32 DGC domain - - - 0.0000000000000000000000000000000000000000000001991 171.0
CSH1_k127_1804443_33 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000001566 184.0
CSH1_k127_1804443_34 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000000000003399 173.0
CSH1_k127_1804443_35 - - - - 0.000000000000000000000000000227 133.0
CSH1_k127_1804443_37 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000005607 106.0
CSH1_k127_1804443_38 oxygen carrier activity K07216 - - 0.00000000000000000000003872 105.0
CSH1_k127_1804443_39 sequence-specific DNA binding K02855,K07506 - - 0.0000000000000000001166 102.0
CSH1_k127_1804443_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 6.628e-201 638.0
CSH1_k127_1804443_41 Universal stress protein - - - 0.000000000000001695 87.0
CSH1_k127_1804443_42 - - - - 0.000000000004243 68.0
CSH1_k127_1804443_43 Hemerythrin HHE cation binding K07322 - - 0.00000001025 61.0
CSH1_k127_1804443_44 Endoribonuclease L-PSP - - - 0.0007843 43.0
CSH1_k127_1804443_5 Nitronate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 613.0
CSH1_k127_1804443_6 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 607.0
CSH1_k127_1804443_7 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 571.0
CSH1_k127_1804443_8 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 539.0
CSH1_k127_1804443_9 protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 533.0
CSH1_k127_1830816_0 Efflux pump membrane transporter K18138 - - 0.0 1274.0
CSH1_k127_1830816_1 ABC transporter, ATP-binding protein K18893 - - 5.19e-298 926.0
CSH1_k127_1830816_10 Domain of unknown function (DUF3482) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 396.0
CSH1_k127_1830816_11 Methyltransferase K06983 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 366.0
CSH1_k127_1830816_12 Including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 365.0
CSH1_k127_1830816_13 phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 333.0
CSH1_k127_1830816_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 328.0
CSH1_k127_1830816_15 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 314.0
CSH1_k127_1830816_16 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 301.0
CSH1_k127_1830816_17 Secretion system type I outer membrane efflux pump lipoprotein NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005014 293.0
CSH1_k127_1830816_18 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006204 276.0
CSH1_k127_1830816_19 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004871 257.0
CSH1_k127_1830816_2 CoA-binding domain protein K09181 - - 1.733e-266 848.0
CSH1_k127_1830816_20 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000000000000000000000001585 211.0
CSH1_k127_1830816_21 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K01802,K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000004136 192.0
CSH1_k127_1830816_22 - - - - 0.0000000000000000000000000000000000000000000000005792 197.0
CSH1_k127_1830816_23 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000001843 186.0
CSH1_k127_1830816_24 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000001776 119.0
CSH1_k127_1830816_25 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000002099 116.0
CSH1_k127_1830816_3 COG0457 FOG TPR repeat - - - 2.753e-228 731.0
CSH1_k127_1830816_4 catalyzes the formation of indole and pyruvate from tryptophan K01667 - 4.1.99.1 3.832e-223 702.0
CSH1_k127_1830816_5 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 584.0
CSH1_k127_1830816_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 587.0
CSH1_k127_1830816_7 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 561.0
CSH1_k127_1830816_8 arylsulfatase A K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 528.0
CSH1_k127_1830816_9 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 402.0
CSH1_k127_1846080_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.206e-229 717.0
CSH1_k127_1846080_1 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 621.0
CSH1_k127_1846080_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000001169 201.0
CSH1_k127_1846080_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000007075 176.0
CSH1_k127_1846080_4 Thioredoxin-like - - - 0.0000000000000000000000000006545 122.0
CSH1_k127_1861857_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.007e-233 744.0
CSH1_k127_1861857_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 524.0
CSH1_k127_1861857_2 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 435.0
CSH1_k127_1861857_3 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000005928 182.0
CSH1_k127_1861857_4 Belongs to the peptidase S8 family K14645 GO:0005575,GO:0005576 - 0.000000000000000000000000002509 124.0
CSH1_k127_1861857_5 Domain of unknown function (DUF4266) - - - 0.0000000000000000000005913 97.0
CSH1_k127_1861857_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000002905 79.0
CSH1_k127_1900803_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 4.85e-280 880.0
CSH1_k127_1900803_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.489e-216 686.0
CSH1_k127_1900803_2 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 550.0
CSH1_k127_1900803_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 490.0
CSH1_k127_1900803_4 COG2939 Carboxypeptidase C (cathepsin A) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 454.0
CSH1_k127_1900803_5 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000003504 184.0
CSH1_k127_1900803_6 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000009939 139.0
CSH1_k127_1900803_7 Saccharopine dehydrogenase - - - 0.00000002746 56.0
CSH1_k127_1913566_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 0.0 1315.0
CSH1_k127_1913566_1 ABC transporter - - - 3.981e-297 918.0
CSH1_k127_1913566_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000006961 153.0
CSH1_k127_1913566_11 - - - - 0.00000000000002322 84.0
CSH1_k127_1913566_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.944e-207 651.0
CSH1_k127_1913566_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 486.0
CSH1_k127_1913566_4 histidine ammonia-lyase activity K01745 GO:0003674,GO:0003824,GO:0004397,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 457.0
CSH1_k127_1913566_5 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 389.0
CSH1_k127_1913566_6 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 373.0
CSH1_k127_1913566_7 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000001383 231.0
CSH1_k127_1913566_8 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000009488 239.0
CSH1_k127_1913566_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000004818 193.0
CSH1_k127_1927802_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 2.299e-260 811.0
CSH1_k127_1927802_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.432e-239 758.0
CSH1_k127_1927802_10 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 390.0
CSH1_k127_1927802_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 372.0
CSH1_k127_1927802_12 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 356.0
CSH1_k127_1927802_13 Histidine kinase K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 368.0
CSH1_k127_1927802_14 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 357.0
CSH1_k127_1927802_15 abc transporter atp-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 345.0
CSH1_k127_1927802_16 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 342.0
CSH1_k127_1927802_17 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 299.0
CSH1_k127_1927802_18 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003309 289.0
CSH1_k127_1927802_19 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000046 264.0
CSH1_k127_1927802_2 FtsX-like permease family K02004 - - 7.214e-204 667.0
CSH1_k127_1927802_20 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003694 264.0
CSH1_k127_1927802_21 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04487 - 2.8.1.7 0.00000000000000000000000000001433 121.0
CSH1_k127_1927802_22 - - - - 0.00000000000000000000002402 108.0
CSH1_k127_1927802_24 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000000000000002053 80.0
CSH1_k127_1927802_25 - - - - 0.00000000000001464 76.0
CSH1_k127_1927802_26 arylsulfatase activity - - - 0.00000000004981 67.0
CSH1_k127_1927802_3 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 532.0
CSH1_k127_1927802_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 497.0
CSH1_k127_1927802_5 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 496.0
CSH1_k127_1927802_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 454.0
CSH1_k127_1927802_7 Transketolase, pyrimidine binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 469.0
CSH1_k127_1927802_8 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 430.0
CSH1_k127_1927802_9 Dehydrogenase E1 component K11381,K21416 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 416.0
CSH1_k127_1949603_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 8.165e-320 985.0
CSH1_k127_1949603_1 Domain of unknown function (DUF4478) K06966 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464,GO:0047405 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 595.0
CSH1_k127_1949603_10 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000006123 163.0
CSH1_k127_1949603_11 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000005784 139.0
CSH1_k127_1949603_12 Belongs to the bacterial histone-like protein family - - - 0.000000000000000000000000000001884 123.0
CSH1_k127_1949603_13 Domain of unknown function (DUF4426) - - - 0.0000000000000000000001159 107.0
CSH1_k127_1949603_14 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000002672 100.0
CSH1_k127_1949603_2 COG0209 Ribonucleotide reductase, alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 301.0
CSH1_k127_1949603_3 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 295.0
CSH1_k127_1949603_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000326 273.0
CSH1_k127_1949603_5 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000347 267.0
CSH1_k127_1949603_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 261.0
CSH1_k127_1949603_7 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.00000000000000000000000000000000000000000000000000001003 198.0
CSH1_k127_1949603_8 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000002664 186.0
CSH1_k127_1949603_9 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.000000000000000000000000000000000000000003076 159.0
CSH1_k127_1977779_0 Predicted Permease Membrane Region K07085 - - 1.834e-224 708.0
CSH1_k127_1977779_1 Predicted Permease Membrane Region K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 466.0
CSH1_k127_1977779_2 Aminotransferase class I and II K09758 - 4.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 420.0
CSH1_k127_1977779_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 416.0
CSH1_k127_1977779_4 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 396.0
CSH1_k127_1977779_5 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 368.0
CSH1_k127_1977779_6 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 306.0
CSH1_k127_1977779_7 Protein of unknown function (DUF3302) - - - 0.000000000000000000000000000000000000003836 153.0
CSH1_k127_1977779_8 YMGG-like Gly-zipper - - - 0.000000000002571 73.0
CSH1_k127_2019218_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 521.0
CSH1_k127_2019218_1 GMP synthase (glutamine-hydrolyzing) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 475.0
CSH1_k127_2019218_10 - - - - 0.000000212 57.0
CSH1_k127_2019218_11 Kinase-like - GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019538,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032878,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0009906 45.0
CSH1_k127_2019218_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 436.0
CSH1_k127_2019218_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 377.0
CSH1_k127_2019218_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000003839 246.0
CSH1_k127_2019218_5 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000009132 224.0
CSH1_k127_2019218_6 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000003656 209.0
CSH1_k127_2019218_7 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000003288 169.0
CSH1_k127_2019218_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001629 143.0
CSH1_k127_2019218_9 - - - - 0.000000000000781 77.0
CSH1_k127_2031108_0 N-acyl-L-amino acid amidohydrolase K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 510.0
CSH1_k127_2031108_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 505.0
CSH1_k127_2031108_2 A G-specific adenine glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 319.0
CSH1_k127_2031108_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 308.0
CSH1_k127_2031108_4 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008573 306.0
CSH1_k127_2031108_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000003004 156.0
CSH1_k127_2031108_6 Putative adhesin - - - 0.000000000000000000000000000000004031 140.0
CSH1_k127_2049209_0 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 5.177e-266 828.0
CSH1_k127_2049209_1 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 462.0
CSH1_k127_2049209_10 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000002748 186.0
CSH1_k127_2049209_11 Amidohydrolase family - - - 0.00000000000000000000000000000000000000001277 154.0
CSH1_k127_2049209_12 PFAM DoxX K15977 - - 0.00000000000000000000000000000000000000001348 158.0
CSH1_k127_2049209_13 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000002343 121.0
CSH1_k127_2049209_14 - - - - 0.000000000000000000001761 101.0
CSH1_k127_2049209_15 peptidase M20 K01295 - 3.4.17.11 0.000000000002419 68.0
CSH1_k127_2049209_16 2Fe-2S -binding domain protein K02192 - - 0.00000000131 65.0
CSH1_k127_2049209_2 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 393.0
CSH1_k127_2049209_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 376.0
CSH1_k127_2049209_4 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 304.0
CSH1_k127_2049209_5 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0020037,GO:0030003,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0097159,GO:0097577,GO:0098771,GO:1901363 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000008214 243.0
CSH1_k127_2049209_6 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000001321 235.0
CSH1_k127_2049209_7 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000003723 241.0
CSH1_k127_2049209_8 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000003265 219.0
CSH1_k127_2049209_9 - - - - 0.0000000000000000000000000000000000000000000000000000004004 205.0
CSH1_k127_2075898_0 radical SAM protein YgiQ - - - 0.0 1090.0
CSH1_k127_2075898_1 PFAM beta-lactamase domain protein K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 521.0
CSH1_k127_2075898_10 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000004807 143.0
CSH1_k127_2075898_11 Putative inner membrane exporter, YdcZ - - - 0.0000000000000000000000001636 111.0
CSH1_k127_2075898_12 TIR domain - - - 0.0000000000000000000000002828 123.0
CSH1_k127_2075898_13 PFAM Rhodanese domain protein - - - 0.000000000000000000001156 104.0
CSH1_k127_2075898_14 Polymer-forming cytoskeletal - - - 0.00000000000000000000967 105.0
CSH1_k127_2075898_15 - - - - 0.00000000000000002681 88.0
CSH1_k127_2075898_16 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000002101 93.0
CSH1_k127_2075898_17 GntP family permease - - - 0.0000000000000005805 81.0
CSH1_k127_2075898_18 - - - - 0.000000002629 63.0
CSH1_k127_2075898_2 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 - 2.7.8.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 404.0
CSH1_k127_2075898_3 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 349.0
CSH1_k127_2075898_4 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005463 269.0
CSH1_k127_2075898_5 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008563 261.0
CSH1_k127_2075898_6 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000000002621 240.0
CSH1_k127_2075898_7 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000005651 200.0
CSH1_k127_2075898_8 domain protein - - - 0.000000000000000000000000000000000000000000000000007191 206.0
CSH1_k127_2075898_9 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000000000001348 184.0
CSH1_k127_209404_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 5.468e-233 725.0
CSH1_k127_209404_1 Cys Met metabolism pyridoxal-phosphate-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 511.0
CSH1_k127_209404_2 receptor K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 497.0
CSH1_k127_209404_3 Nitrite reductase K15864 - 1.7.2.1,1.7.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 440.0
CSH1_k127_209404_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 347.0
CSH1_k127_209404_5 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 344.0
CSH1_k127_2110597_0 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 424.0
CSH1_k127_2110597_1 TonB-dependent Receptor Plug K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 387.0
CSH1_k127_2110597_2 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 314.0
CSH1_k127_2110597_3 adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000002314 265.0
CSH1_k127_2110597_4 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000183 222.0
CSH1_k127_2110597_5 PFAM small multidrug resistance protein K03297 - - 0.00000000000000000000000000000000000000000004376 162.0
CSH1_k127_2110597_6 - - - - 0.000000000000000000000003846 103.0
CSH1_k127_214574_0 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 527.0
CSH1_k127_214574_1 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 522.0
CSH1_k127_214574_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000001353 145.0
CSH1_k127_214574_11 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000009118 132.0
CSH1_k127_214574_12 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000003133 120.0
CSH1_k127_214574_13 Small membrane protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000003587 115.0
CSH1_k127_214574_14 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000000000001863 82.0
CSH1_k127_214574_15 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00002898 55.0
CSH1_k127_214574_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 436.0
CSH1_k127_214574_3 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 417.0
CSH1_k127_214574_4 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 374.0
CSH1_k127_214574_5 Flavin containing amine oxidoreductase K06955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001376 274.0
CSH1_k127_214574_6 short-chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001816 258.0
CSH1_k127_214574_7 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.000000000000000000000000000000000000000000000000000000001578 207.0
CSH1_k127_214574_8 Transcriptional regulator K05800 - - 0.0000000000000000000000000000000000000000000003521 172.0
CSH1_k127_214574_9 Uncharacterised conserved protein (DUF2156) K07027,K14205 - 2.3.2.3 0.00000000000000000000000000000000000000000004335 174.0
CSH1_k127_219978_0 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 503.0
CSH1_k127_219978_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 396.0
CSH1_k127_219978_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 359.0
CSH1_k127_219978_3 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03314 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 309.0
CSH1_k127_219978_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000195 278.0
CSH1_k127_219978_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003205 279.0
CSH1_k127_219978_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000001384 228.0
CSH1_k127_219978_7 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000003417 159.0
CSH1_k127_2240576_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00244 - 1.3.5.4 5e-324 1004.0
CSH1_k127_2240576_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.132e-227 711.0
CSH1_k127_2240576_10 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000314 238.0
CSH1_k127_2240576_11 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000000001205 160.0
CSH1_k127_2240576_12 Acyl-ACP thioesterase K07107 - - 0.000000000000000000000000000000000000001505 154.0
CSH1_k127_2240576_2 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 393.0
CSH1_k127_2240576_3 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 383.0
CSH1_k127_2240576_4 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 335.0
CSH1_k127_2240576_5 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 346.0
CSH1_k127_2240576_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 311.0
CSH1_k127_2240576_7 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 305.0
CSH1_k127_2240576_8 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006254 250.0
CSH1_k127_2240576_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002844 232.0
CSH1_k127_2249322_0 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 442.0
CSH1_k127_2249322_1 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 297.0
CSH1_k127_2249322_2 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 295.0
CSH1_k127_2256208_0 Bacterial protein of unknown function (DUF885) - - - 3.04e-214 683.0
CSH1_k127_2256208_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 589.0
CSH1_k127_2256208_2 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169,K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 523.0
CSH1_k127_2256208_3 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 514.0
CSH1_k127_2256208_4 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 385.0
CSH1_k127_2256208_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K18357 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001734 276.0
CSH1_k127_2256208_6 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000005139 166.0
CSH1_k127_2265381_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.137e-284 880.0
CSH1_k127_2265381_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 552.0
CSH1_k127_2265381_2 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 305.0
CSH1_k127_2265381_3 PFAM Outer membrane protein, OmpA MotB, C-terminal - - - 0.00000000001016 66.0
CSH1_k127_2265381_4 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000005319 63.0
CSH1_k127_2266882_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1475.0
CSH1_k127_2266882_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 344.0
CSH1_k127_2266882_2 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000000000518 158.0
CSH1_k127_2266882_3 - - - - 0.0000000000000000000000000000000007734 137.0
CSH1_k127_227012_0 PFAM Sulfatase - - - 0.0 1176.0
CSH1_k127_227012_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 602.0
CSH1_k127_227012_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 487.0
CSH1_k127_227012_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 390.0
CSH1_k127_227012_4 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000000000005243 220.0
CSH1_k127_227012_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000004062 190.0
CSH1_k127_227012_6 YMGG-like Gly-zipper - - - 0.0000000000000000000000005475 111.0
CSH1_k127_227012_7 - - - - 0.000000000000000001218 92.0
CSH1_k127_2277289_0 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 542.0
CSH1_k127_2277289_1 Alpha/beta hydrolase family K01259,K18457 - 3.4.11.5,3.5.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 404.0
CSH1_k127_2277289_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 344.0
CSH1_k127_2277289_3 Class ii aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002 278.0
CSH1_k127_2300062_0 Alkyl sulfatase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 522.0
CSH1_k127_2300062_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 402.0
CSH1_k127_2300062_2 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001928 276.0
CSH1_k127_2300062_3 PFAM Glutathione S-transferase, N-terminal K03599 - - 0.000000000000000000000000000000000000000000000000000001036 201.0
CSH1_k127_2300062_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000008713 161.0
CSH1_k127_2300062_5 stringent starvation protein b K03600 - - 0.00000000000000000000000000000000001124 141.0
CSH1_k127_2307128_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 546.0
CSH1_k127_2307128_1 Belongs to the Orn Lys Arg decarboxylase class-II family K12526 - 2.7.2.4,4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 349.0
CSH1_k127_2307128_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 334.0
CSH1_k127_2307128_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000004531 150.0
CSH1_k127_2307128_4 MazG-like family - - - 0.0000000000000000000000000000000000006868 146.0
CSH1_k127_2307128_5 Domain of unknown function (DUF3597) - - - 0.000000000000000000000000000000000002938 141.0
CSH1_k127_2325198_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1230.0
CSH1_k127_2325198_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 422.0
CSH1_k127_2325198_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 287.0
CSH1_k127_2325427_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 600.0
CSH1_k127_2325427_1 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 548.0
CSH1_k127_2325427_10 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 344.0
CSH1_k127_2325427_11 PPIC-type PPIASE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 316.0
CSH1_k127_2325427_12 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 290.0
CSH1_k127_2325427_13 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003478 286.0
CSH1_k127_2325427_14 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000004293 202.0
CSH1_k127_2325427_15 PFAM LppC K07121 - - 0.00000000000000000000000000000000000000000000000000001083 213.0
CSH1_k127_2325427_16 - - - - 0.0000000000000000000000004505 113.0
CSH1_k127_2325427_17 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000001125 108.0
CSH1_k127_2325427_18 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000006914 89.0
CSH1_k127_2325427_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 527.0
CSH1_k127_2325427_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 472.0
CSH1_k127_2325427_4 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 443.0
CSH1_k127_2325427_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 434.0
CSH1_k127_2325427_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 447.0
CSH1_k127_2325427_7 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 404.0
CSH1_k127_2325427_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 398.0
CSH1_k127_2325427_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 357.0
CSH1_k127_2351231_0 Oxidoreductase - - - 4.038e-303 941.0
CSH1_k127_2351231_1 Glycine cleavage T-protein C-terminal barrel domain - - - 8.705e-207 651.0
CSH1_k127_2351231_10 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 322.0
CSH1_k127_2351231_11 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000009063 233.0
CSH1_k127_2351231_12 proteolysis - - - 0.0000000000000000000000000000000000000000000001638 179.0
CSH1_k127_2351231_13 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000001402 110.0
CSH1_k127_2351231_2 Thi4 family - - - 6.263e-205 649.0
CSH1_k127_2351231_3 protein conserved in bacteria - - - 5.931e-198 634.0
CSH1_k127_2351231_4 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 511.0
CSH1_k127_2351231_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 457.0
CSH1_k127_2351231_6 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 475.0
CSH1_k127_2351231_7 abc transporter atp-binding protein K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 367.0
CSH1_k127_2351231_8 Sodium ABC transporter permease K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 368.0
CSH1_k127_2351231_9 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 330.0
CSH1_k127_2415986_0 COG1643 HrpA-like helicases K03578 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 4.476e-318 1017.0
CSH1_k127_2415986_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 581.0
CSH1_k127_2415986_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 580.0
CSH1_k127_2415986_3 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 308.0
CSH1_k127_2415986_4 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000000000000009656 184.0
CSH1_k127_2415986_5 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000002047 178.0
CSH1_k127_2415986_6 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000002426 130.0
CSH1_k127_2415986_7 protein acetylation - - - 0.0000000000000000000004581 104.0
CSH1_k127_2415986_8 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000006709 85.0
CSH1_k127_2416708_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 402.0
CSH1_k127_2416708_1 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 418.0
CSH1_k127_2416708_2 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000002077 178.0
CSH1_k127_2446419_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.0 1065.0
CSH1_k127_2446419_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000849 178.0
CSH1_k127_2473462_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 620.0
CSH1_k127_2473462_1 E3 component of 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 557.0
CSH1_k127_2473462_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 305.0
CSH1_k127_2473462_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000002729 235.0
CSH1_k127_2473462_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000003572 192.0
CSH1_k127_249032_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 494.0
CSH1_k127_249032_1 belongs to the histidinol- phosphatase family K01089 - 3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 444.0
CSH1_k127_249032_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 362.0
CSH1_k127_249032_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 333.0
CSH1_k127_249032_4 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 330.0
CSH1_k127_249032_5 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000001098 251.0
CSH1_k127_249032_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000008441 240.0
CSH1_k127_249032_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0033554,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0050896,GO:0051716,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000001237 217.0
CSH1_k127_249032_8 protein, YerC YecD - - - 0.0000000000000000000000002981 108.0
CSH1_k127_249032_9 Major Facilitator Superfamily - - - 0.000000000145 64.0
CSH1_k127_2500942_0 protein conserved in bacteria K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 594.0
CSH1_k127_2500942_1 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 516.0
CSH1_k127_2500942_10 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00000000024 69.0
CSH1_k127_2500942_11 Lipopolysaccharide-assembly, LptC-related - - - 0.000004458 57.0
CSH1_k127_2500942_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 453.0
CSH1_k127_2500942_3 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000921 428.0
CSH1_k127_2500942_4 ABC transporter, ATP-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 347.0
CSH1_k127_2500942_5 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 317.0
CSH1_k127_2500942_6 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 306.0
CSH1_k127_2500942_7 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000008482 195.0
CSH1_k127_2500942_8 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000009384 169.0
CSH1_k127_2500942_9 sigma (54) modulation protein K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000014 116.0
CSH1_k127_2509774_0 amine dehydrogenase activity - - - 4.072e-269 861.0
CSH1_k127_2509774_1 Ferrous iron transport protein B C terminus K04759 - - 2.211e-253 797.0
CSH1_k127_2509774_10 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 312.0
CSH1_k127_2509774_11 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006582 286.0
CSH1_k127_2509774_12 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000001002 240.0
CSH1_k127_2509774_13 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000001395 190.0
CSH1_k127_2509774_14 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000002692 184.0
CSH1_k127_2509774_15 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000001604 156.0
CSH1_k127_2509774_16 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000009025 155.0
CSH1_k127_2509774_17 Protease prsW family - - - 0.0000000000000000000000000000000000002148 154.0
CSH1_k127_2509774_18 - - - - 0.0000000000000000000000000000000000004824 146.0
CSH1_k127_2509774_19 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000004719 149.0
CSH1_k127_2509774_2 HypF finger - - - 5.1e-253 810.0
CSH1_k127_2509774_20 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564 - 0.00000000000000000000000000000000002762 139.0
CSH1_k127_2509774_21 - - - - 0.000000000000000000000000000001792 124.0
CSH1_k127_2509774_22 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000004188 111.0
CSH1_k127_2509774_23 Anti-sigma-K factor rskA - - - 0.000000000000000000000000008287 121.0
CSH1_k127_2509774_24 SnoaL-like domain - - - 0.00000000000000000000004515 103.0
CSH1_k127_2509774_25 FeoA K04758 - - 0.00000000000003707 78.0
CSH1_k127_2509774_26 Sporulation related domain - - - 0.00001059 56.0
CSH1_k127_2509774_3 ABC transporter C-terminal domain K15738 - - 6.399e-202 646.0
CSH1_k127_2509774_4 Hydrogenase formation hypA family K04654 GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 564.0
CSH1_k127_2509774_5 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 527.0
CSH1_k127_2509774_6 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 507.0
CSH1_k127_2509774_7 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008589 454.0
CSH1_k127_2509774_8 AIR synthase related protein, N-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 442.0
CSH1_k127_2509774_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 379.0
CSH1_k127_2513703_0 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 422.0
CSH1_k127_2513703_1 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 387.0
CSH1_k127_2513703_10 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.0000000000000000000000000000000000000000000000000002975 205.0
CSH1_k127_2513703_11 Protein of unknown function (DUF3224) - - - 0.000000000000000000000000000000000000000000002676 169.0
CSH1_k127_2513703_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000001881 116.0
CSH1_k127_2513703_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 378.0
CSH1_k127_2513703_3 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 311.0
CSH1_k127_2513703_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003745 280.0
CSH1_k127_2513703_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001198 225.0
CSH1_k127_2513703_6 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000006154 230.0
CSH1_k127_2513703_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000001181 218.0
CSH1_k127_2513703_8 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000000000000000000000005455 214.0
CSH1_k127_2513703_9 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000003034 192.0
CSH1_k127_2519056_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1020.0
CSH1_k127_2519056_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 3.569e-241 762.0
CSH1_k127_2519056_10 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 319.0
CSH1_k127_2519056_11 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 306.0
CSH1_k127_2519056_12 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 287.0
CSH1_k127_2519056_13 PFAM methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004445 283.0
CSH1_k127_2519056_14 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005795 275.0
CSH1_k127_2519056_15 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000006129 261.0
CSH1_k127_2519056_16 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01664 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000003134 249.0
CSH1_k127_2519056_17 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001903 254.0
CSH1_k127_2519056_18 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004677 243.0
CSH1_k127_2519056_19 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000002094 237.0
CSH1_k127_2519056_2 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 604.0
CSH1_k127_2519056_20 Bacterial transferase hexapeptide (six repeats) - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000008537 214.0
CSH1_k127_2519056_21 E3 Ubiquitin ligase - - - 0.00000000000000000000000000000000000000000000000000000000001478 218.0
CSH1_k127_2519056_22 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000005038 205.0
CSH1_k127_2519056_23 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000004649 203.0
CSH1_k127_2519056_24 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000553 190.0
CSH1_k127_2519056_25 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000000000000001442 171.0
CSH1_k127_2519056_26 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.0000000000000000000000000000000000000001055 162.0
CSH1_k127_2519056_27 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000004251 118.0
CSH1_k127_2519056_28 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000001076 117.0
CSH1_k127_2519056_29 - - - - 0.0000000000000001115 86.0
CSH1_k127_2519056_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 537.0
CSH1_k127_2519056_4 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 508.0
CSH1_k127_2519056_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 468.0
CSH1_k127_2519056_6 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 379.0
CSH1_k127_2519056_7 serine protease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 385.0
CSH1_k127_2519056_8 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 370.0
CSH1_k127_2519056_9 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 355.0
CSH1_k127_2591556_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 334.0
CSH1_k127_2591556_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 324.0
CSH1_k127_2591556_2 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 317.0
CSH1_k127_2591556_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000006843 162.0
CSH1_k127_2591556_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000005638 157.0
CSH1_k127_2591556_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000008292 141.0
CSH1_k127_2591556_6 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000003331 80.0
CSH1_k127_2630491_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.262e-218 687.0
CSH1_k127_2630491_1 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 576.0
CSH1_k127_2630491_2 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 506.0
CSH1_k127_2630491_3 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000008572 230.0
CSH1_k127_2630491_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000002237 186.0
CSH1_k127_2630491_5 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.000000000000000000000000000001627 126.0
CSH1_k127_2630491_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000004869 119.0
CSH1_k127_2647975_0 Belongs to the GcvT family K00315 - 1.5.8.4 4.214e-321 1000.0
CSH1_k127_2647975_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 623.0
CSH1_k127_2647975_10 - - - - 0.00000000004725 72.0
CSH1_k127_2647975_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 510.0
CSH1_k127_2647975_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 383.0
CSH1_k127_2647975_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000002951 250.0
CSH1_k127_2647975_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000001718 222.0
CSH1_k127_2647975_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000000001152 198.0
CSH1_k127_2647975_7 Domain of unknown function (DUF1820) - - - 0.0000000000000000000000000000000000001048 144.0
CSH1_k127_2647975_8 Type VI secretion K07169,K11894,K11913 - - 0.000000000000000000000000000002041 137.0
CSH1_k127_2647975_9 BetI-type transcriptional repressor, C-terminal - - - 0.000000000000000000000002213 111.0
CSH1_k127_2726853_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 531.0
CSH1_k127_2726853_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 335.0
CSH1_k127_2726853_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002796 281.0
CSH1_k127_2726853_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000001376 214.0
CSH1_k127_2756087_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 549.0
CSH1_k127_2756087_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 411.0
CSH1_k127_2756087_2 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 301.0
CSH1_k127_2756087_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004511 252.0
CSH1_k127_2756087_4 B12 binding domain - - - 0.0000000000000000000000000000000000000000000002296 183.0
CSH1_k127_2756087_5 MlaD protein K02067 - - 0.0000000000000000000000000000000000001782 153.0
CSH1_k127_2756087_6 transport system, auxiliary component K18480 - - 0.0000178 56.0
CSH1_k127_2760724_0 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 510.0
CSH1_k127_2760724_1 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 411.0
CSH1_k127_2760724_2 short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 301.0
CSH1_k127_2760724_3 Pseudouridine synthase K06175 - 5.4.99.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003003 280.0
CSH1_k127_2760724_4 Iron-containing redox enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002791 268.0
CSH1_k127_2760724_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003362 256.0
CSH1_k127_2760724_6 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000004451 220.0
CSH1_k127_2760724_7 DNA-templated transcription, initiation K03088,K03091 - - 0.000000000000000000000000000000007722 135.0
CSH1_k127_2760724_8 Thermostable hemolysin - - - 0.00000000000000000000000000000001342 138.0
CSH1_k127_2770516_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 4.405e-235 741.0
CSH1_k127_2770516_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 6.992e-212 661.0
CSH1_k127_2770516_2 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 446.0
CSH1_k127_2770516_3 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 390.0
CSH1_k127_2770516_4 SBF-like CPA transporter family (DUF4137) K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 318.0
CSH1_k127_2770516_5 Branched-chain amino acid aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002364 281.0
CSH1_k127_2770516_6 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005477 261.0
CSH1_k127_2770516_7 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001016 204.0
CSH1_k127_2770516_8 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000407 184.0
CSH1_k127_2770516_9 SnoaL-like polyketide cyclase K21700 - - 0.0002795 52.0
CSH1_k127_2792052_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1190.0
CSH1_k127_2792052_1 Peptidase family M13 K07386 - - 6.413e-245 778.0
CSH1_k127_2792052_10 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004109 262.0
CSH1_k127_2792052_11 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001203 232.0
CSH1_k127_2792052_12 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000001068 215.0
CSH1_k127_2792052_13 subfamily IA, variant 3 K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000001274 209.0
CSH1_k127_2792052_14 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000001437 170.0
CSH1_k127_2792052_15 TPM domain - - - 0.000000000000000000000000000000000000000000003783 176.0
CSH1_k127_2792052_16 chain release factor K15034 - - 0.000000000000000000000000000000000008634 140.0
CSH1_k127_2792052_17 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000001182 109.0
CSH1_k127_2792052_18 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.000000000000000000001466 105.0
CSH1_k127_2792052_19 small protein containing a coiled-coil domain - - - 0.00000000000001334 80.0
CSH1_k127_2792052_2 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 9.865e-220 709.0
CSH1_k127_2792052_20 Protein of unknown function (DUF3301) - - - 0.00000000001579 68.0
CSH1_k127_2792052_3 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 519.0
CSH1_k127_2792052_4 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 339.0
CSH1_k127_2792052_5 SMART Peptidoglycan-binding Lysin subgroup K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 336.0
CSH1_k127_2792052_6 Inositol monophosphatase family K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 308.0
CSH1_k127_2792052_7 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001444 278.0
CSH1_k127_2792052_8 Phage tail sheath C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002071 290.0
CSH1_k127_2792052_9 Methyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001887 262.0
CSH1_k127_2792322_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 6.512e-212 679.0
CSH1_k127_2792322_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 400.0
CSH1_k127_2792322_2 Belongs to the GARS family K01945,K13713 GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000002479 229.0
CSH1_k127_2792322_3 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000001525 102.0
CSH1_k127_2792322_4 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.000000000000000001826 93.0
CSH1_k127_2792322_5 Protein of unknown function (DUF3426) - - - 0.000000001121 71.0
CSH1_k127_2835191_0 Nitrite and sulphite reductase 4Fe-4S domain K00381 - 1.8.1.2 1.827e-247 789.0
CSH1_k127_2835191_1 FAD binding domain K00380 - 1.8.1.2 7.835e-210 669.0
CSH1_k127_2835191_10 - - - - 0.000000000002728 77.0
CSH1_k127_2835191_11 Tetratricopeptide repeat - - - 0.000000000003529 81.0
CSH1_k127_2835191_12 Biopolymer transport protein ExbD/TolR - - - 0.00000002078 62.0
CSH1_k127_2835191_2 Tetratricopeptide repeat - - - 2.395e-207 681.0
CSH1_k127_2835191_3 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 517.0
CSH1_k127_2835191_4 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 401.0
CSH1_k127_2835191_5 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 335.0
CSH1_k127_2835191_6 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000002717 238.0
CSH1_k127_2835191_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000008686 186.0
CSH1_k127_2835191_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000006182 128.0
CSH1_k127_2835191_9 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000003687 113.0
CSH1_k127_2835377_0 Sulfatase - - - 3.472e-288 890.0
CSH1_k127_2835377_1 Sulfatase K01130 - 3.1.6.1 3.845e-216 681.0
CSH1_k127_2835377_2 Radical SAM superfamily K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 318.0
CSH1_k127_2835377_3 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000000000000000000001115 175.0
CSH1_k127_2835377_4 - - - - 0.00000000000000000000000000000000000000000001471 169.0
CSH1_k127_2835377_5 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000000001235 121.0
CSH1_k127_2835377_6 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000003212 100.0
CSH1_k127_2985331_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 567.0
CSH1_k127_2985331_1 of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 495.0
CSH1_k127_2985331_2 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 484.0
CSH1_k127_2985331_3 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 467.0
CSH1_k127_2985331_4 cobalamin binding K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 380.0
CSH1_k127_2985331_5 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 368.0
CSH1_k127_2985331_6 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002604 253.0
CSH1_k127_2985331_7 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000002714 228.0
CSH1_k127_2985331_8 Virulence factor - - - 0.000000000000000000000000000000001024 134.0
CSH1_k127_2985331_9 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000471 95.0
CSH1_k127_2991669_0 AAA-like domain - - - 2.225e-245 781.0
CSH1_k127_2991669_1 COG4772 Outer membrane receptor for Fe3 -dicitrate K16091 - - 1.038e-209 676.0
CSH1_k127_2991669_10 Protein of unknown function (DUF3011) - - - 0.0000000000000000000000000006926 125.0
CSH1_k127_2991669_11 Protein of unknown function VcgC/VcgE (DUF2780) - - - 0.00000000000003331 80.0
CSH1_k127_2991669_2 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 467.0
CSH1_k127_2991669_3 ATPase activity K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 405.0
CSH1_k127_2991669_4 Binding-protein-dependent transport system inner membrane component K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 349.0
CSH1_k127_2991669_5 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 344.0
CSH1_k127_2991669_6 amino acid K03294,K13868 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 307.0
CSH1_k127_2991669_7 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002902 259.0
CSH1_k127_2991669_8 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000929 197.0
CSH1_k127_2991669_9 maturation - - - 0.0000000000000000000000000000000007843 143.0
CSH1_k127_3001635_0 aconitate hydratase K01681,K20455 - 4.2.1.117,4.2.1.3 0.0 1528.0
CSH1_k127_3001635_1 Peptidase family M1 domain - - - 0.0 1340.0
CSH1_k127_3001635_2 PrpF protein K09788 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0071704,GO:0072329,GO:1901575 - 1.268e-220 691.0
CSH1_k127_3001635_3 Belongs to the citrate synthase family K01659 - 2.3.3.5 6.665e-216 687.0
CSH1_k127_3001635_4 Pfam:DUF955 K21686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 538.0
CSH1_k127_3001635_5 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 462.0
CSH1_k127_3001635_6 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 447.0
CSH1_k127_3001635_7 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 353.0
CSH1_k127_3001635_8 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000000000000007613 191.0
CSH1_k127_3001635_9 2-methylcitrate dehydratase K01720 - 4.2.1.79 0.000000000000000000000000000000000015 147.0
CSH1_k127_300859_0 ABC transporter - - - 6.313e-237 744.0
CSH1_k127_300859_1 Insecticidal toxin complex protein TcaC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 569.0
CSH1_k127_300859_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000001636 145.0
CSH1_k127_300859_11 Thioesterase superfamily - - - 0.000000000000000000000000000000001974 134.0
CSH1_k127_300859_12 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000000000000000000242 130.0
CSH1_k127_300859_13 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000254 139.0
CSH1_k127_300859_14 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000944 111.0
CSH1_k127_300859_15 PQ loop repeat K15383 - - 0.000000000000000000000001389 106.0
CSH1_k127_300859_16 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000001332 93.0
CSH1_k127_300859_17 self proteolysis - - - 0.0000000121 70.0
CSH1_k127_300859_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 463.0
CSH1_k127_300859_3 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 451.0
CSH1_k127_300859_4 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 401.0
CSH1_k127_300859_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 307.0
CSH1_k127_300859_6 Acid phosphatase homologues K09474 - 3.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000002978 233.0
CSH1_k127_300859_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000001473 199.0
CSH1_k127_300859_8 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000000001276 188.0
CSH1_k127_300859_9 SnoaL-like domain - - - 0.0000000000000000000000000000000000001701 154.0
CSH1_k127_3016150_0 response regulator receiver K02487,K06596 - - 0.0 1104.0
CSH1_k127_3016150_1 COG0840 Methyl-accepting chemotaxis protein K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 391.0
CSH1_k127_3016150_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000003209 240.0
CSH1_k127_3016150_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000003553 226.0
CSH1_k127_3016150_4 CheW-like domain K06598 - - 0.00000000000000000001262 100.0
CSH1_k127_3033428_0 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 1.958e-230 731.0
CSH1_k127_3033428_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 621.0
CSH1_k127_3033428_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 451.0
CSH1_k127_3033428_3 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 454.0
CSH1_k127_3033428_4 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000001013 251.0
CSH1_k127_3042418_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 574.0
CSH1_k127_3042418_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 339.0
CSH1_k127_3042418_2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 325.0
CSH1_k127_3042418_3 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006396 289.0
CSH1_k127_3042418_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000007954 265.0
CSH1_k127_3042418_5 FimV C-terminal K08086 - - 0.000000000000000000000000000000000000000000000000000000000000000002336 253.0
CSH1_k127_3042418_6 Diguanylate cyclase K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000003311 201.0
CSH1_k127_3042418_7 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000002734 154.0
CSH1_k127_3045939_0 TonB dependent receptor - - - 3.738e-305 963.0
CSH1_k127_3045939_1 COG3420 Nitrous oxidase accessory protein - - - 6.951e-225 707.0
CSH1_k127_3045939_10 PQQ enzyme repeat K17760 - 1.1.9.1 0.00000000000003419 74.0
CSH1_k127_3045939_11 Transglycosylase associated protein - - - 0.0000000034 62.0
CSH1_k127_3045939_2 COG1858 Cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 545.0
CSH1_k127_3045939_3 Alkane 1-monooxygenase K00496,K10616,K15757 - 1.14.15.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 337.0
CSH1_k127_3045939_4 esterase lipase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000003853 227.0
CSH1_k127_3045939_5 Alkylated DNA repair protein - - - 0.0000000000000000000000000000000000000000000000000000000000001347 218.0
CSH1_k127_3045939_6 COG2863 Cytochrome c553 - - - 0.000000000000000000000000000000000000000000000000000002768 199.0
CSH1_k127_3045939_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000004592 155.0
CSH1_k127_3045939_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000003716 135.0
CSH1_k127_3045939_9 oxidoreductase FAD NAD(P)-binding domain protein K14581 - 1.18.1.7 0.00000000000000000001137 105.0
CSH1_k127_3052273_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1542.0
CSH1_k127_3052273_1 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 1.763e-277 867.0
CSH1_k127_3052273_10 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000007887 145.0
CSH1_k127_3052273_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 496.0
CSH1_k127_3052273_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 450.0
CSH1_k127_3052273_4 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 374.0
CSH1_k127_3052273_5 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 351.0
CSH1_k127_3052273_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 332.0
CSH1_k127_3052273_7 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 321.0
CSH1_k127_3052273_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001168 261.0
CSH1_k127_3052273_9 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000001982 212.0
CSH1_k127_3112106_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1382.0
CSH1_k127_3112106_1 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 1.44e-279 886.0
CSH1_k127_3112106_10 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 342.0
CSH1_k127_3112106_11 Protoporphyrinogen oxidase K00230 GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001227 263.0
CSH1_k127_3112106_12 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000000000000000000000000001078 229.0
CSH1_k127_3112106_13 hemolysin III K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000006572 226.0
CSH1_k127_3112106_14 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000003294 201.0
CSH1_k127_3112106_15 Short chain fatty acid transporter K02106 - - 0.0000000000000000000000000000000000000000000000002747 196.0
CSH1_k127_3112106_16 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000002581 160.0
CSH1_k127_3112106_17 - - - - 0.000000000000000000000000000000000000000007998 158.0
CSH1_k127_3112106_18 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000004554 78.0
CSH1_k127_3112106_19 - - - - 0.000000000229 68.0
CSH1_k127_3112106_2 Flavin-binding monooxygenase-like - - - 5.737e-235 738.0
CSH1_k127_3112106_20 - - - - 0.0000006891 57.0
CSH1_k127_3112106_3 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.061e-200 639.0
CSH1_k127_3112106_4 amidohydrolase - - - 5.566e-199 632.0
CSH1_k127_3112106_5 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 556.0
CSH1_k127_3112106_6 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 413.0
CSH1_k127_3112106_7 Acyltransferase ws dgat mgat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 401.0
CSH1_k127_3112106_8 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 383.0
CSH1_k127_3112106_9 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 361.0
CSH1_k127_3117168_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 2.572e-253 824.0
CSH1_k127_3117168_1 3-hydroxyacyl-coa dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 8.903e-215 687.0
CSH1_k127_3117168_10 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 366.0
CSH1_k127_3117168_11 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 363.0
CSH1_k127_3117168_12 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 338.0
CSH1_k127_3117168_13 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 338.0
CSH1_k127_3117168_14 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 325.0
CSH1_k127_3117168_15 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 317.0
CSH1_k127_3117168_16 Domain of unknown function (DUF4040) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006325 270.0
CSH1_k127_3117168_17 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 267.0
CSH1_k127_3117168_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001351 248.0
CSH1_k127_3117168_19 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002344 225.0
CSH1_k127_3117168_2 Proton-conducting membrane transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 616.0
CSH1_k127_3117168_20 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000368 226.0
CSH1_k127_3117168_21 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000001915 217.0
CSH1_k127_3117168_22 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000006029 197.0
CSH1_k127_3117168_23 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000838 199.0
CSH1_k127_3117168_24 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000005018 203.0
CSH1_k127_3117168_25 Pilus assembly protein PilZ K02676 - - 0.0000000000000000000000000000000000000000000000001522 179.0
CSH1_k127_3117168_26 Domain of unknown function (DUF4377) - - - 0.000000000000000000000000000000000000000000000001529 185.0
CSH1_k127_3117168_27 DNA polymerase III, delta subunit, C terminal K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000001703 177.0
CSH1_k127_3117168_28 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000000000000001611 150.0
CSH1_k127_3117168_29 General secretion pathway protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000000000000000000000000000000000009999 146.0
CSH1_k127_3117168_3 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 612.0
CSH1_k127_3117168_30 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000002042 128.0
CSH1_k127_3117168_31 acetyltransferase K22441 - 2.3.1.57 0.0000000000000000000000000000002269 138.0
CSH1_k127_3117168_32 - - - - 0.000000000000000000000000001125 121.0
CSH1_k127_3117168_33 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.000000000000000000000000004258 126.0
CSH1_k127_3117168_34 Rhomboid family - - - 0.00000000000000000000000004621 115.0
CSH1_k127_3117168_35 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.000000000000000000001718 101.0
CSH1_k127_3117168_36 MTH538 TIR-like domain (DUF1863) - - - 0.0000000000000000003036 94.0
CSH1_k127_3117168_37 - - - - 0.00000000000000001564 84.0
CSH1_k127_3117168_38 Type II secretion system (T2SS), protein I K02458 - - 0.0000000000000001539 89.0
CSH1_k127_3117168_39 Type II transport protein GspH K02457 - - 0.0000000000007649 78.0
CSH1_k127_3117168_4 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 596.0
CSH1_k127_3117168_40 Type II secretion system (T2SS), protein N K02463 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00007189 53.0
CSH1_k127_3117168_5 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 550.0
CSH1_k127_3117168_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 547.0
CSH1_k127_3117168_7 alcohol dehydrogenase K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 451.0
CSH1_k127_3117168_8 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 439.0
CSH1_k127_3117168_9 component I K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 429.0
CSH1_k127_3123942_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.473e-307 979.0
CSH1_k127_3123942_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 453.0
CSH1_k127_3123942_2 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 423.0
CSH1_k127_3123942_3 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 298.0
CSH1_k127_3123942_4 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000002742 273.0
CSH1_k127_3123942_5 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.00000000001457 76.0
CSH1_k127_3151612_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.407e-256 799.0
CSH1_k127_3151612_1 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 8.024e-236 749.0
CSH1_k127_3151612_10 GGDEF domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 468.0
CSH1_k127_3151612_11 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 458.0
CSH1_k127_3151612_12 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 408.0
CSH1_k127_3151612_13 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 426.0
CSH1_k127_3151612_14 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 406.0
CSH1_k127_3151612_15 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 391.0
CSH1_k127_3151612_16 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 388.0
CSH1_k127_3151612_17 DnaJ-class molecular chaperone K05516 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 389.0
CSH1_k127_3151612_18 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 370.0
CSH1_k127_3151612_19 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 353.0
CSH1_k127_3151612_2 COG2217 Cation transport ATPase K01533 - 3.6.3.4 7.639e-224 722.0
CSH1_k127_3151612_20 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 336.0
CSH1_k127_3151612_21 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 330.0
CSH1_k127_3151612_22 subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 308.0
CSH1_k127_3151612_23 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003657 269.0
CSH1_k127_3151612_24 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000002286 252.0
CSH1_k127_3151612_25 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000002052 230.0
CSH1_k127_3151612_26 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000001655 224.0
CSH1_k127_3151612_27 universal stress protein K14055 - - 0.00000000000000000000000000000000000000000000000000006502 198.0
CSH1_k127_3151612_28 Sugar (and other) transporter K07552 - - 0.000000000000000000000000000000000000000000000000000295 209.0
CSH1_k127_3151612_29 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000008374 179.0
CSH1_k127_3151612_3 protein conserved in bacteria - - - 6.563e-214 680.0
CSH1_k127_3151612_30 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000001181 184.0
CSH1_k127_3151612_31 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000003932 172.0
CSH1_k127_3151612_32 Complex I intermediate-associated protein 30 - - - 0.000000000000000000000000000000000000000003603 160.0
CSH1_k127_3151612_33 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000001389 164.0
CSH1_k127_3151612_34 Ferredoxin - - - 0.0000000000000000000000000000000002806 135.0
CSH1_k127_3151612_35 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000006685 128.0
CSH1_k127_3151612_36 Protein-glutamate methylesterase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000128 100.0
CSH1_k127_3151612_37 Protein of unknown function (DUF2892) - - - 0.00000000000000000005725 92.0
CSH1_k127_3151612_39 - - - - 0.00000000000379 72.0
CSH1_k127_3151612_4 TIGRFAM cytochrome c oxidase accessory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 597.0
CSH1_k127_3151612_40 MerR HTH family regulatory protein K18997 - - 0.000000000006395 70.0
CSH1_k127_3151612_41 Cytochrome oxidase maturation protein - - - 0.00000000001172 72.0
CSH1_k127_3151612_42 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.00000000001184 66.0
CSH1_k127_3151612_43 FixH K09926 - - 0.000000001372 65.0
CSH1_k127_3151612_5 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 594.0
CSH1_k127_3151612_6 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 584.0
CSH1_k127_3151612_7 Belongs to the thiolase family K00626 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009446 572.0
CSH1_k127_3151612_8 poly-beta-hydroxybutyrate polymerase K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 576.0
CSH1_k127_3151612_9 alcohol dehydrogenase K00001 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 451.0
CSH1_k127_3153989_0 COG0457 FOG TPR repeat - - - 1.493e-273 859.0
CSH1_k127_3153989_1 Receptor - - - 1.427e-242 775.0
CSH1_k127_3153989_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.276e-236 747.0
CSH1_k127_3153989_3 Belongs to the BCCT transporter (TC 2.A.15) family K03451 - - 6.427e-207 659.0
CSH1_k127_3153989_4 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 462.0
CSH1_k127_3153989_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006154 280.0
CSH1_k127_3153989_6 HD phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000417 245.0
CSH1_k127_3153989_7 Maleate cis-trans isomerase K01799,K06033 - 4.1.1.76,5.2.1.1 0.00000000000000000000000000000000000000000000000000000000009956 212.0
CSH1_k127_3153989_8 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000001006 76.0
CSH1_k127_3153989_9 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000006681 61.0
CSH1_k127_3171062_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 4.404e-264 825.0
CSH1_k127_3171062_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 595.0
CSH1_k127_3171062_2 LacI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 382.0
CSH1_k127_3171062_3 Transcriptional regulator K19337 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001181 286.0
CSH1_k127_3171062_4 COG0477 Permeases of the major facilitator superfamily K16211 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004561 265.0
CSH1_k127_3171062_5 Aldolase K01625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000002623 232.0
CSH1_k127_3171062_6 Glycine zipper - - - 0.0000000000000000000000000000000000000001608 157.0
CSH1_k127_3171062_7 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000001542 152.0
CSH1_k127_3171062_8 Phosphoglycerol transferase - - - 0.000000000001428 70.0
CSH1_k127_3203482_0 Peptidase M16 - - - 0.0 1027.0
CSH1_k127_3203482_1 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 486.0
CSH1_k127_3203482_2 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 317.0
CSH1_k127_3203482_3 OmpW family K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000008209 198.0
CSH1_k127_3203482_4 - - - - 0.0000000000000000000000000000000000000000000005221 173.0
CSH1_k127_3203482_5 OmpA family - - - 0.00000000000000000000000000001145 137.0
CSH1_k127_321348_0 Histidine kinase - - - 5.5e-321 1018.0
CSH1_k127_321348_1 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 322.0
CSH1_k127_321348_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001925 256.0
CSH1_k127_3240066_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 4.338e-248 775.0
CSH1_k127_3240066_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 6.706e-209 663.0
CSH1_k127_3240066_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000001727 248.0
CSH1_k127_3240066_11 PFAM peptidase S16 lon domain protein K07157 - - 0.00000000000000000000000000000000000000000000000000000004178 206.0
CSH1_k127_3240066_12 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000006241 188.0
CSH1_k127_3240066_13 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000005798 168.0
CSH1_k127_3240066_14 glycosyl - - - 0.000000000000000000000000000000000001453 160.0
CSH1_k127_3240066_15 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000008546 109.0
CSH1_k127_3240066_16 - - - - 0.00000000000000000004094 94.0
CSH1_k127_3240066_17 - - - - 0.00000000002721 74.0
CSH1_k127_3240066_18 - - - - 0.00008114 54.0
CSH1_k127_3240066_2 Aminotransferase K01845 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 1.535e-194 615.0
CSH1_k127_3240066_3 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 581.0
CSH1_k127_3240066_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 534.0
CSH1_k127_3240066_5 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 460.0
CSH1_k127_3240066_6 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 391.0
CSH1_k127_3240066_7 PFAM O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 305.0
CSH1_k127_3240066_8 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000276 299.0
CSH1_k127_3240066_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007852 276.0
CSH1_k127_3301978_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1041.0
CSH1_k127_3301978_1 DNA segregation ATPase FtsK SpoIIIE K03466 - - 1.942e-285 895.0
CSH1_k127_3301978_10 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 445.0
CSH1_k127_3301978_11 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 419.0
CSH1_k127_3301978_12 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 376.0
CSH1_k127_3301978_13 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 347.0
CSH1_k127_3301978_14 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 339.0
CSH1_k127_3301978_15 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 351.0
CSH1_k127_3301978_16 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 341.0
CSH1_k127_3301978_17 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 336.0
CSH1_k127_3301978_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 297.0
CSH1_k127_3301978_19 Conserved TM helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 292.0
CSH1_k127_3301978_2 choline dehydrogenase activity - - - 3.894e-216 687.0
CSH1_k127_3301978_20 PFAM Alpha beta hydrolase fold-3 domain protein K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002909 284.0
CSH1_k127_3301978_21 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001282 275.0
CSH1_k127_3301978_22 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000009725 209.0
CSH1_k127_3301978_23 Bacterial regulatory proteins, crp family K01420 - - 0.0000000000000000000000000000000000000000000000000001984 193.0
CSH1_k127_3301978_24 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000006443 185.0
CSH1_k127_3301978_25 Acetyltransferase (GNAT) K06977 - - 0.00000000000000000000000000000000000000000006654 166.0
CSH1_k127_3301978_26 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000004615 174.0
CSH1_k127_3301978_27 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000007998 158.0
CSH1_k127_3301978_28 Adenylate cyclase - - - 0.0000000000000000000000000000000000000003139 172.0
CSH1_k127_3301978_29 Cupin domain - - - 0.00000000000000000000000000000000000001253 151.0
CSH1_k127_3301978_3 PFAM transcriptional regulator domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 586.0
CSH1_k127_3301978_30 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000001381 149.0
CSH1_k127_3301978_31 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000001092 130.0
CSH1_k127_3301978_32 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000002057 128.0
CSH1_k127_3301978_33 - - - - 0.0000000000000000000000000001316 123.0
CSH1_k127_3301978_34 TonB dependent receptor - - - 0.00000000000000000000000002846 123.0
CSH1_k127_3301978_36 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000002062 101.0
CSH1_k127_3301978_37 - - - - 0.0000000000000000003684 94.0
CSH1_k127_3301978_38 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000001291 78.0
CSH1_k127_3301978_39 Peptidoglycan-binding domain 1 protein - - - 0.0000000000351 68.0
CSH1_k127_3301978_4 aminopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 576.0
CSH1_k127_3301978_40 PFAM VanZ - - - 0.0000000023 65.0
CSH1_k127_3301978_41 Resolvase, N terminal domain - - - 0.00000001381 57.0
CSH1_k127_3301978_5 ATPase (AAA K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 558.0
CSH1_k127_3301978_6 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 532.0
CSH1_k127_3301978_7 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 526.0
CSH1_k127_3301978_8 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 516.0
CSH1_k127_3301978_9 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 498.0
CSH1_k127_3319309_0 acetolactate synthase K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 1.481e-299 929.0
CSH1_k127_3319309_1 Sortilin, neurotensin receptor 3, - - - 1.951e-269 848.0
CSH1_k127_3319309_10 Lactoylglutathione lyase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000001489 240.0
CSH1_k127_3319309_11 Carbohydrate-selective porin, OprB family K07267 - - 0.000000000000000000000000000000000000000000004231 178.0
CSH1_k127_3319309_12 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000113 156.0
CSH1_k127_3319309_13 PFAM DSBA oxidoreductase - - - 0.00000000000000000000000000000000000008123 151.0
CSH1_k127_3319309_14 alpha/beta hydrolase fold - - - 0.000000000000004197 84.0
CSH1_k127_3319309_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 608.0
CSH1_k127_3319309_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 510.0
CSH1_k127_3319309_4 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 499.0
CSH1_k127_3319309_5 RND efflux system, outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 449.0
CSH1_k127_3319309_6 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 390.0
CSH1_k127_3319309_7 Protein of unknown function (DUF808) K09781 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 381.0
CSH1_k127_3319309_8 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 364.0
CSH1_k127_3319309_9 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 352.0
CSH1_k127_3404184_0 1,4-alpha-glucan branching enzyme activity K00700,K01187,K01236,K17734 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,3.2.1.141,3.2.1.20 4.142e-269 847.0
CSH1_k127_3404184_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 3.501e-250 790.0
CSH1_k127_3404184_2 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 311.0
CSH1_k127_3417558_0 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 445.0
CSH1_k127_3417558_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000002013 220.0
CSH1_k127_3417558_2 transcriptional regulator - - - 0.00000000000000000000000000000000000001344 154.0
CSH1_k127_3417558_3 cyclic nucleotide binding K01420,K10914,K21561 - - 0.00000000000002613 81.0
CSH1_k127_3459723_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K20034 - 6.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 611.0
CSH1_k127_3459723_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 412.0
CSH1_k127_3459723_2 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 0.00000000000000000000000000000000000000000000000000000006569 214.0
CSH1_k127_3459723_3 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000003486 213.0
CSH1_k127_3459723_4 Exopolysaccharide synthesis, ExoD - - - 0.0000000000000000000000000000000000000000004568 175.0
CSH1_k127_3459723_5 glyoxalase III activity - - - 0.00000002877 61.0
CSH1_k127_3459723_6 SBF-like CPA transporter family (DUF4137) K03453 - - 0.00000009054 53.0
CSH1_k127_3495997_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 451.0
CSH1_k127_3495997_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 321.0
CSH1_k127_3495997_2 Activator of Hsp90 ATPase 1 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008106 250.0
CSH1_k127_3495997_3 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000514 203.0
CSH1_k127_3495997_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000004005 183.0
CSH1_k127_3495997_5 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.0000000000000000000000000000000000000000003722 168.0
CSH1_k127_3495997_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000004431 99.0
CSH1_k127_3609538_0 Phosphate acyltransferases K15781 - 2.3.1.51,3.1.3.3 4.939e-201 642.0
CSH1_k127_3609538_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 592.0
CSH1_k127_3609538_2 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 595.0
CSH1_k127_3609538_3 AMP-binding enzyme K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 544.0
CSH1_k127_3609538_4 TonB dependent receptor K02014 - - 0.0000000000000000000000000002049 116.0
CSH1_k127_3609538_5 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.0000000000000000006857 95.0
CSH1_k127_3720816_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 614.0
CSH1_k127_3720816_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 448.0
CSH1_k127_3720816_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 420.0
CSH1_k127_3720816_3 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008921 361.0
CSH1_k127_3720816_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 355.0
CSH1_k127_3720816_5 hydrolase activity, acting on ester bonds K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 315.0
CSH1_k127_3720816_6 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000004645 190.0
CSH1_k127_3722368_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 475.0
CSH1_k127_3722368_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 455.0
CSH1_k127_3722368_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 362.0
CSH1_k127_3722368_3 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001991 286.0
CSH1_k127_3722368_4 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000008352 180.0
CSH1_k127_3722368_5 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000008045 157.0
CSH1_k127_3722368_6 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.000000000000000000000000000000000009024 145.0
CSH1_k127_3722368_7 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000001695 98.0
CSH1_k127_3722368_8 Putative aminopeptidase - - - 0.0001351 46.0
CSH1_k127_373964_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 514.0
CSH1_k127_373964_1 response regulator K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 443.0
CSH1_k127_373964_2 signal transduction histidine kinase K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 336.0
CSH1_k127_373964_3 penicillin-binding protein - - - 0.0000000000001669 80.0
CSH1_k127_3776642_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2324.0
CSH1_k127_3776642_1 one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high K00371 - 1.7.5.1 1.036e-313 964.0
CSH1_k127_3776642_10 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000176 151.0
CSH1_k127_3776642_12 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000000001368 86.0
CSH1_k127_3776642_13 Adenylate cyclase - - - 0.0000000000001643 78.0
CSH1_k127_3776642_14 PAS domain - - - 0.00000002255 59.0
CSH1_k127_3776642_15 Cytochrome c, class I - - - 0.0000001509 57.0
CSH1_k127_3776642_2 Nitrate nitrite transporter K02575 - - 5.167e-245 763.0
CSH1_k127_3776642_3 Ethylbenzene dehydrogenase - - - 1.062e-216 686.0
CSH1_k127_3776642_4 LacY proton/sugar symporter K02575 - - 1.121e-203 645.0
CSH1_k127_3776642_5 nitrate reductase K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 342.0
CSH1_k127_3776642_6 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 305.0
CSH1_k127_3776642_7 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 292.0
CSH1_k127_3776642_8 nitrate reductase K00373 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 305.0
CSH1_k127_3776642_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002129 269.0
CSH1_k127_3780552_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1159.0
CSH1_k127_3780552_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 527.0
CSH1_k127_3780552_10 - - - - 0.000001888 50.0
CSH1_k127_3780552_11 Recombinase zinc beta ribbon domain - - - 0.000009353 48.0
CSH1_k127_3780552_2 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000001525 161.0
CSH1_k127_3780552_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000001856 151.0
CSH1_k127_3780552_4 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000001344 142.0
CSH1_k127_3780552_5 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000000002253 139.0
CSH1_k127_3780552_6 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000000000000001055 105.0
CSH1_k127_3780552_7 - - - - 0.00000000000000000005343 98.0
CSH1_k127_3780552_8 - - - - 0.00000000000000003305 87.0
CSH1_k127_3780552_9 - - - - 0.0000000001348 68.0
CSH1_k127_3788583_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 2.243e-251 789.0
CSH1_k127_3788583_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 6.811e-237 740.0
CSH1_k127_3788583_10 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 488.0
CSH1_k127_3788583_11 Coenzyme A transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 469.0
CSH1_k127_3788583_12 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 469.0
CSH1_k127_3788583_13 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 438.0
CSH1_k127_3788583_14 Amino acid permease K11735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 439.0
CSH1_k127_3788583_15 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 435.0
CSH1_k127_3788583_16 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 436.0
CSH1_k127_3788583_17 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 411.0
CSH1_k127_3788583_18 Periplasmic solute binding protein K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 361.0
CSH1_k127_3788583_19 TIGRFAM TonB-dependent heme hemoglobin receptor family protein K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 377.0
CSH1_k127_3788583_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 2.221e-214 674.0
CSH1_k127_3788583_20 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 389.0
CSH1_k127_3788583_21 Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 355.0
CSH1_k127_3788583_22 UPF0114 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 302.0
CSH1_k127_3788583_23 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009382 278.0
CSH1_k127_3788583_24 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001354 282.0
CSH1_k127_3788583_25 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000006337 243.0
CSH1_k127_3788583_26 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002007 236.0
CSH1_k127_3788583_27 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000003774 233.0
CSH1_k127_3788583_28 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000000000002577 132.0
CSH1_k127_3788583_29 Peptidase family M3 K01410 - 3.4.24.59 0.0000000006157 72.0
CSH1_k127_3788583_3 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 7.585e-207 655.0
CSH1_k127_3788583_30 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000001425 57.0
CSH1_k127_3788583_4 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 1.258e-204 663.0
CSH1_k127_3788583_5 DNA polymerase X family K02347 - - 7.767e-196 621.0
CSH1_k127_3788583_6 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 599.0
CSH1_k127_3788583_7 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 525.0
CSH1_k127_3788583_8 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008592 497.0
CSH1_k127_3788583_9 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 495.0
CSH1_k127_3792972_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1337.0
CSH1_k127_3792972_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.528e-293 914.0
CSH1_k127_3792972_10 PFAM Cytochrome P450 K14338 - 1.14.14.1,1.6.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 344.0
CSH1_k127_3792972_11 quinolinate catabolic process K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 335.0
CSH1_k127_3792972_12 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 316.0
CSH1_k127_3792972_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 316.0
CSH1_k127_3792972_14 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 316.0
CSH1_k127_3792972_15 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001025 280.0
CSH1_k127_3792972_16 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003602 278.0
CSH1_k127_3792972_17 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001229 267.0
CSH1_k127_3792972_18 Rnf-Nqr subunit, membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008628 247.0
CSH1_k127_3792972_19 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000007536 236.0
CSH1_k127_3792972_2 PFAM biotin lipoyl attachment domain-containing protein K00382 - 1.8.1.4 1.779e-232 736.0
CSH1_k127_3792972_20 PFAM Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005061 232.0
CSH1_k127_3792972_21 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000002076 226.0
CSH1_k127_3792972_22 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000003656 209.0
CSH1_k127_3792972_23 Part of a membrane complex involved in electron transport - - - 0.000000000000000000000000000000000000000000000000000003349 198.0
CSH1_k127_3792972_24 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000000000000000000000000000000000005395 212.0
CSH1_k127_3792972_25 Domain of unknown function (DUF374) - - - 0.0000000000000000000000000000000000000000001185 169.0
CSH1_k127_3792972_26 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000799 163.0
CSH1_k127_3792972_27 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000001262 166.0
CSH1_k127_3792972_28 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000007032 157.0
CSH1_k127_3792972_29 belongs to the Fur family K09826 - - 0.0000000000000000000000000000000007599 138.0
CSH1_k127_3792972_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 638.0
CSH1_k127_3792972_30 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000009164 135.0
CSH1_k127_3792972_31 Type II transport protein GspH K08084 - - 0.0000000000000000000001647 105.0
CSH1_k127_3792972_32 COG4970 Tfp pilus assembly protein FimT K08084 - - 0.000000000000000003737 94.0
CSH1_k127_3792972_33 TIGRFAM type IV pilus modification protein PilV K02671 - - 0.000000000000382 77.0
CSH1_k127_3792972_34 Fe-S protein K06938 - - 0.000000001028 62.0
CSH1_k127_3792972_35 Type IV pilus assembly protein PilX C-term K02673 - - 0.00003488 53.0
CSH1_k127_3792972_36 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000657 53.0
CSH1_k127_3792972_37 Type IV Pilus-assembly protein W K02672 - - 0.0001721 53.0
CSH1_k127_3792972_4 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 595.0
CSH1_k127_3792972_5 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 467.0
CSH1_k127_3792972_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 459.0
CSH1_k127_3792972_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 425.0
CSH1_k127_3792972_8 Belongs to the peptidase M17 family K01255,K01259 - 3.4.11.1,3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 362.0
CSH1_k127_3792972_9 Part of a membrane complex involved in electron transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 361.0
CSH1_k127_3793873_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 395.0
CSH1_k127_3793873_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 315.0
CSH1_k127_3793873_2 Dual specificity phosphatase, catalytic domain - - - 0.0000000000000000000000000003742 130.0
CSH1_k127_3793873_3 ADP-ribosylation crystallin J1 K05521 - 3.2.2.24 0.0000000000000000000000001176 123.0
CSH1_k127_3793873_4 amino acid K03294 - - 0.0001682 46.0
CSH1_k127_3844689_0 peptidase M20 - - - 8.174e-205 646.0
CSH1_k127_3844689_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 496.0
CSH1_k127_3844689_10 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 316.0
CSH1_k127_3844689_11 Preprotein translocase subunit TatD K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 309.0
CSH1_k127_3844689_12 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001352 266.0
CSH1_k127_3844689_13 Peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000002791 244.0
CSH1_k127_3844689_14 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000003884 213.0
CSH1_k127_3844689_15 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000000000001967 179.0
CSH1_k127_3844689_16 Uncharacterized protein conserved in bacteria (DUF2058) K09912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000006955 152.0
CSH1_k127_3844689_17 MAPEG family K07136 - - 0.000000000000000000006651 96.0
CSH1_k127_3844689_2 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 435.0
CSH1_k127_3844689_3 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 437.0
CSH1_k127_3844689_4 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 399.0
CSH1_k127_3844689_5 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 391.0
CSH1_k127_3844689_6 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 376.0
CSH1_k127_3844689_7 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009658 379.0
CSH1_k127_3844689_8 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 332.0
CSH1_k127_3844689_9 electron transfer flavoprotein beta subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 324.0
CSH1_k127_3862429_0 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 451.0
CSH1_k127_3862429_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 310.0
CSH1_k127_3862429_2 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000001362 179.0
CSH1_k127_3862429_3 Protein of unknown function (DUF1298) - - - 0.00000000119 60.0
CSH1_k127_3902095_0 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 575.0
CSH1_k127_3902095_1 Retinal pigment epithelial membrane protein K11159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 511.0
CSH1_k127_3902095_2 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 402.0
CSH1_k127_3902095_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 338.0
CSH1_k127_3902095_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 318.0
CSH1_k127_3902095_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 296.0
CSH1_k127_3902095_6 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003042 261.0
CSH1_k127_3902095_7 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000003011 220.0
CSH1_k127_3902095_8 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000003485 123.0
CSH1_k127_3902095_9 Lipocalin-like domain - - - 0.00000000000000000000008724 104.0
CSH1_k127_3904753_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.971e-197 625.0
CSH1_k127_3904753_1 cystathionine K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 495.0
CSH1_k127_3904753_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 464.0
CSH1_k127_3904753_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 366.0
CSH1_k127_3904753_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005251 268.0
CSH1_k127_3904753_5 Belongs to the AB hydrolase superfamily. MetX family K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000492 263.0
CSH1_k127_3906010_0 Aminotransferase class-V K14287 - 2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 488.0
CSH1_k127_3906010_1 carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 312.0
CSH1_k127_3906010_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 309.0
CSH1_k127_3906010_3 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002646 281.0
CSH1_k127_3906010_4 TLC ATP/ADP transporter - - - 0.000000000002088 70.0
CSH1_k127_390663_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 6.737e-214 687.0
CSH1_k127_390663_1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
CSH1_k127_390663_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000005272 253.0
CSH1_k127_390663_3 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001348 187.0
CSH1_k127_390663_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000004294 177.0
CSH1_k127_390663_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000001233 136.0
CSH1_k127_390663_6 membrane - - - 0.00000000000000000000000003124 120.0
CSH1_k127_3979663_0 Carboxyl transferase domain K13778 - 6.4.1.5 3.087e-252 788.0
CSH1_k127_3979663_1 Biotin carboxylase C-terminal domain K01968,K13777 - 6.4.1.4,6.4.1.5 3.545e-230 735.0
CSH1_k127_3979663_10 NnrU protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001647 238.0
CSH1_k127_3979663_11 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000002439 222.0
CSH1_k127_3979663_12 Transcriptional regulator K18900 - - 0.000000000000000000000000000000000000000000000000000000000003559 220.0
CSH1_k127_3979663_2 acyl-CoA dehydrogenase K11731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 573.0
CSH1_k127_3979663_3 PFAM Pyridoxal-dependent decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 563.0
CSH1_k127_3979663_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 542.0
CSH1_k127_3979663_5 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 449.0
CSH1_k127_3979663_6 Strictosidine synthase K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 434.0
CSH1_k127_3979663_7 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 353.0
CSH1_k127_3979663_8 Protein of unknown function (DUF1302) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002254 270.0
CSH1_k127_3979663_9 Enoyl-CoA hydratase/isomerase K13779 - 4.2.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000002658 248.0
CSH1_k127_3991803_0 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 459.0
CSH1_k127_3991803_1 Pyruvate formate lyase-activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 447.0
CSH1_k127_3991803_2 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 308.0
CSH1_k127_4018007_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2544.0
CSH1_k127_4018007_1 2,4-dienoyl-coa reductase K00219 - 1.3.1.34 0.0 1017.0
CSH1_k127_4018007_10 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000001169 214.0
CSH1_k127_4018007_11 subfamily IA, variant 1 K20862 - 3.1.3.102,3.1.3.104 0.000000000000000000000000000000000000000000000000000102 194.0
CSH1_k127_4018007_12 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000005942 202.0
CSH1_k127_4018007_13 - - - - 0.000000000000000000000000000000000000000002684 163.0
CSH1_k127_4018007_14 - - - - 0.0000000000000000000000000000000001344 144.0
CSH1_k127_4018007_15 - - - - 0.000000000000000000000000000001147 127.0
CSH1_k127_4018007_16 CBS domain - - - 0.000000000000000003074 95.0
CSH1_k127_4018007_17 Transcription factor zinc-finger - - - 0.00000000001694 77.0
CSH1_k127_4018007_18 - - - - 0.000008954 52.0
CSH1_k127_4018007_2 Formiminotransferase-cyclodeaminase K00603,K13990 - 2.1.2.5,4.3.1.4 6.738e-198 636.0
CSH1_k127_4018007_3 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 505.0
CSH1_k127_4018007_4 valine-pyruvate transaminase activity K00835 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009042,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0030632,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 431.0
CSH1_k127_4018007_5 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 346.0
CSH1_k127_4018007_6 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 321.0
CSH1_k127_4018007_7 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 301.0
CSH1_k127_4018007_8 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000001656 241.0
CSH1_k127_4018007_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002655 240.0
CSH1_k127_4026828_0 FAD dependent oxidoreductase - - - 1.487e-229 721.0
CSH1_k127_4026828_1 Carboxylesterase family K01050,K03929 - 3.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 597.0
CSH1_k127_4026828_2 cobalt chelatase K09883 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 572.0
CSH1_k127_4026828_3 GMC oxidoreductase K00108 - 1.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 393.0
CSH1_k127_4026828_4 NADPH quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 383.0
CSH1_k127_4026828_5 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 364.0
CSH1_k127_4026828_6 TIGRFAM cobalt chelatase, pCobS small subunit K09882 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 328.0
CSH1_k127_4026828_7 Short-chain dehydrogenase reductase sdr K00046,K00059 - 1.1.1.100,1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 321.0
CSH1_k127_4026828_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000004224 156.0
CSH1_k127_4060597_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit - - - 1.865e-201 641.0
CSH1_k127_4060597_1 nucleoside-diphosphate sugar epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 599.0
CSH1_k127_4060597_10 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000009464 165.0
CSH1_k127_4060597_11 ATP synthase subunit D K02120 - - 0.0000000000000000000000000007552 124.0
CSH1_k127_4060597_12 - - - - 0.00000000000000000000000003569 120.0
CSH1_k127_4060597_13 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.000000000000000000000002785 114.0
CSH1_k127_4060597_14 PilZ domain - - - 0.0000000000000397 75.0
CSH1_k127_4060597_15 ATP synthase (F/14-kDa) subunit - - - 0.000000001814 62.0
CSH1_k127_4060597_2 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 574.0
CSH1_k127_4060597_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 401.0
CSH1_k127_4060597_4 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 361.0
CSH1_k127_4060597_5 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 355.0
CSH1_k127_4060597_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 338.0
CSH1_k127_4060597_7 cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 309.0
CSH1_k127_4060597_8 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004846 282.0
CSH1_k127_4060597_9 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000001281 239.0
CSH1_k127_4069255_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 618.0
CSH1_k127_4069255_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 518.0
CSH1_k127_4069255_10 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009228 288.0
CSH1_k127_4069255_11 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000002925 142.0
CSH1_k127_4069255_12 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.00000000000000000000000000000003581 134.0
CSH1_k127_4069255_13 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000002364 91.0
CSH1_k127_4069255_14 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000001334 76.0
CSH1_k127_4069255_15 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000001516 68.0
CSH1_k127_4069255_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 507.0
CSH1_k127_4069255_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 481.0
CSH1_k127_4069255_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 483.0
CSH1_k127_4069255_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 461.0
CSH1_k127_4069255_6 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 348.0
CSH1_k127_4069255_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 342.0
CSH1_k127_4069255_8 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 335.0
CSH1_k127_4069255_9 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 307.0
CSH1_k127_4100313_0 Concanavalin A-like lectin/glucanases superfamily - - - 3.492e-295 927.0
CSH1_k127_4100313_1 - - - - 2.642e-229 721.0
CSH1_k127_4100313_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 497.0
CSH1_k127_4100313_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 357.0
CSH1_k127_4100313_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 347.0
CSH1_k127_4100313_5 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001091 290.0
CSH1_k127_4100313_6 - - - - 0.00000000000000000000000000000000000000000000000000000000006991 209.0
CSH1_k127_4100313_8 Glutathione peroxidase - - - 0.0000000000000000000003225 102.0
CSH1_k127_4125075_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 4.864e-262 826.0
CSH1_k127_4125075_1 Thiolase, C-terminal domain K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0033554,GO:0033812,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 572.0
CSH1_k127_4125075_2 CoA-transferase family III K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 440.0
CSH1_k127_4125075_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 407.0
CSH1_k127_4125075_4 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 411.0
CSH1_k127_4125075_5 L-carnitine dehydratase bile acid-inducible protein F K18289 - 2.8.3.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 411.0
CSH1_k127_4125075_6 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000001223 238.0
CSH1_k127_4145508_0 Bacterial protein of unknown function (DUF885) - - - 4.289e-195 626.0
CSH1_k127_4145508_1 Rieske 2Fe-2S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 581.0
CSH1_k127_4145508_10 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000003823 182.0
CSH1_k127_4145508_11 Guanyl-specific ribonuclease Sa - - - 0.00000000000000000000000000000000000003445 149.0
CSH1_k127_4145508_12 Barstar (barnase inhibitor) - - - 0.0000000000000000000001826 103.0
CSH1_k127_4145508_13 BetI-type transcriptional repressor, C-terminal - - - 0.000000000000000000002029 102.0
CSH1_k127_4145508_2 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 572.0
CSH1_k127_4145508_3 Belongs to the purine-cytosine permease (2.A.39) family K03457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 576.0
CSH1_k127_4145508_4 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine K17735 - 1.1.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 547.0
CSH1_k127_4145508_5 Short-chain specific acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 534.0
CSH1_k127_4145508_6 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 492.0
CSH1_k127_4145508_7 PFAM Ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 478.0
CSH1_k127_4145508_8 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000008336 208.0
CSH1_k127_4145508_9 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000001561 188.0
CSH1_k127_4199423_0 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 403.0
CSH1_k127_4199423_1 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000002698 223.0
CSH1_k127_4199423_2 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000009861 215.0
CSH1_k127_4199423_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000001227 180.0
CSH1_k127_4199423_4 membrane - - - 0.00000000000000000000000000000000000001487 148.0
CSH1_k127_4199423_5 Protein-S-isoprenylcysteine methyltransferase - - - 0.00000000000000000000000000000000000003952 148.0
CSH1_k127_4199423_6 protein conserved in bacteria K09984 - - 0.0000000000000000000000000000001798 135.0
CSH1_k127_4199423_7 alcohol dehydrogenase K00344 - 1.6.5.5 0.00000003455 59.0
CSH1_k127_4208101_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1218.0
CSH1_k127_4208101_1 Zn-dependent hydrolases including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 377.0
CSH1_k127_4208101_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001898 252.0
CSH1_k127_4208101_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002047 246.0
CSH1_k127_4208101_4 Sulfurtransferase - - - 0.000000000000000000000000000009237 124.0
CSH1_k127_4208101_5 transcriptional - - - 0.000000000000000000000000001718 117.0
CSH1_k127_4208101_6 sulfurtransferase - - - 0.000000000000000005012 92.0
CSH1_k127_4208101_7 Membrane fusogenic activity K09806 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000001046 68.0
CSH1_k127_4351622_0 ATP-dependent helicase K03579 - 3.6.4.13 5.531e-276 876.0
CSH1_k127_4351622_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 6.955e-259 801.0
CSH1_k127_4351622_10 pfam nlp p60 K13695 - - 0.000000000000000000000000000001094 128.0
CSH1_k127_4351622_11 - - - - 0.0000000000000000000009341 99.0
CSH1_k127_4351622_2 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 434.0
CSH1_k127_4351622_3 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 421.0
CSH1_k127_4351622_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 378.0
CSH1_k127_4351622_5 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 331.0
CSH1_k127_4351622_6 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 325.0
CSH1_k127_4351622_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000007281 186.0
CSH1_k127_4351622_8 protein conserved in bacteria K09793 - - 0.0000000000000000000000000000000000000000000001088 176.0
CSH1_k127_4351622_9 Bacterial type II/III secretion system short domain - - - 0.0000000000000000000000000000003612 141.0
CSH1_k127_4397152_0 PCRF K02835 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 481.0
CSH1_k127_4397152_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 427.0
CSH1_k127_4397152_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 365.0
CSH1_k127_4397152_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 334.0
CSH1_k127_4397152_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000003663 270.0
CSH1_k127_4397152_5 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000003982 241.0
CSH1_k127_4397152_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000005406 213.0
CSH1_k127_4397152_7 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000000009217 99.0
CSH1_k127_4397152_8 - - - - 0.000006007 51.0
CSH1_k127_4406050_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 473.0
CSH1_k127_4406050_1 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 448.0
CSH1_k127_4406050_10 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000002523 143.0
CSH1_k127_4406050_11 Belongs to the DnaA family. HdA subfamily K10763 - - 0.000000000000000000000000001462 118.0
CSH1_k127_4406050_12 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.00000000000000000002779 93.0
CSH1_k127_4406050_13 Belongs to the DnaA family. HdA subfamily K10763 - - 0.000000000000000001844 87.0
CSH1_k127_4406050_15 protein conserved in bacteria K09938 - - 0.0000000000008841 79.0
CSH1_k127_4406050_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 437.0
CSH1_k127_4406050_3 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 379.0
CSH1_k127_4406050_4 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 359.0
CSH1_k127_4406050_5 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000003175 261.0
CSH1_k127_4406050_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000002503 252.0
CSH1_k127_4406050_7 Exopolysaccharide synthesis, ExoD - - - 0.00000000000000000000000000000000000000000000000000000000000000000001078 239.0
CSH1_k127_4406050_8 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000008352 180.0
CSH1_k127_4443689_0 Major facilitator superfamily K08218 - - 7.921e-211 663.0
CSH1_k127_4443689_1 FAD dependent oxidoreductase K07077 - - 2.175e-195 618.0
CSH1_k127_4443689_2 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 407.0
CSH1_k127_4443689_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001902 282.0
CSH1_k127_4443689_4 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008879 287.0
CSH1_k127_4443689_5 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000001533 158.0
CSH1_k127_4443689_6 Rieske 2Fe-2S - - - 0.0000000000000000000000000004053 118.0
CSH1_k127_4443689_7 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000005533 116.0
CSH1_k127_4443689_8 - - - - 0.000000000000007002 79.0
CSH1_k127_4443689_9 Pfam Transposase IS66 - - - 0.00000000009879 72.0
CSH1_k127_4483576_0 FAD linked oxidase domain protein K00803,K11472 - 2.5.1.26 1.78e-212 669.0
CSH1_k127_4483576_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 503.0
CSH1_k127_4483576_2 transporter K08368 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 473.0
CSH1_k127_4483576_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 343.0
CSH1_k127_4483576_4 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K21826 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003179 286.0
CSH1_k127_4483576_5 FGGY family of carbohydrate kinases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007983 259.0
CSH1_k127_4484683_0 ABC-type multidrug transport system ATPase and permease K06147 - - 6.837e-284 884.0
CSH1_k127_4484683_1 Bacterial extracellular solute-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 451.0
CSH1_k127_4484683_2 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 449.0
CSH1_k127_4484683_3 Binding-protein-dependent transport system inner membrane component K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 386.0
CSH1_k127_4484683_4 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 308.0
CSH1_k127_4484683_5 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000299 250.0
CSH1_k127_4484683_6 PhnA domain K06193 - - 0.0000000000000000000000001146 109.0
CSH1_k127_4492000_0 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 595.0
CSH1_k127_4492000_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 576.0
CSH1_k127_4492000_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 422.0
CSH1_k127_4492000_3 NADH:flavin oxidoreductase / NADH oxidase family K00317,K21833 - 1.5.8.1,1.5.8.2 0.0000000000000000000000000000000000000000000000000000000002437 208.0
CSH1_k127_4492000_4 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000001361 161.0
CSH1_k127_4492526_0 histidine kinase, dimerisation and phosphoacceptor region - - - 5.455e-202 674.0
CSH1_k127_4492526_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 601.0
CSH1_k127_4492526_10 - - - - 0.00000000000000000000000000000000000000000000000000005039 195.0
CSH1_k127_4492526_11 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000004194 162.0
CSH1_k127_4492526_12 OmpA-like transmembrane domain - - - 0.0000000000000000000000000000007599 128.0
CSH1_k127_4492526_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000002527 119.0
CSH1_k127_4492526_14 LysE type translocator - - - 0.000000000000000002851 94.0
CSH1_k127_4492526_15 Domain of unknown function (DUF4136) - - - 0.0000000008487 66.0
CSH1_k127_4492526_17 Domain of unknown function (DUF4136) - - - 0.0001018 47.0
CSH1_k127_4492526_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 515.0
CSH1_k127_4492526_3 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 377.0
CSH1_k127_4492526_4 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 363.0
CSH1_k127_4492526_5 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 303.0
CSH1_k127_4492526_6 PFAM Response regulator receiver domain, Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 293.0
CSH1_k127_4492526_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000002746 216.0
CSH1_k127_4492526_8 PFAM cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000002437 216.0
CSH1_k127_4492526_9 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000005978 201.0
CSH1_k127_4508041_0 N-acyl-D-aspartate D-glutamate deacylase - - - 3.912e-210 670.0
CSH1_k127_4508041_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 602.0
CSH1_k127_4508041_2 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 520.0
CSH1_k127_4508041_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 491.0
CSH1_k127_4508041_4 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 291.0
CSH1_k127_4508041_5 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003268 272.0
CSH1_k127_4508041_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000004046 78.0
CSH1_k127_4508198_0 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 2.244e-279 871.0
CSH1_k127_4508198_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 6.854e-249 771.0
CSH1_k127_4508198_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008125 275.0
CSH1_k127_4508198_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005573 265.0
CSH1_k127_4508198_12 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000008351 244.0
CSH1_k127_4508198_13 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000423 219.0
CSH1_k127_4508198_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000001021 179.0
CSH1_k127_4508198_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000002979 160.0
CSH1_k127_4508198_16 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000002274 107.0
CSH1_k127_4508198_17 - - - - 0.0000003758 55.0
CSH1_k127_4508198_2 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 8.095e-244 776.0
CSH1_k127_4508198_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 2.959e-231 724.0
CSH1_k127_4508198_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.48e-210 660.0
CSH1_k127_4508198_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 556.0
CSH1_k127_4508198_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 473.0
CSH1_k127_4508198_7 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 337.0
CSH1_k127_4508198_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 314.0
CSH1_k127_4508198_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 303.0
CSH1_k127_4524231_0 Protein of unknown function, DUF255 K06888 - - 1.343e-248 787.0
CSH1_k127_4524231_1 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 592.0
CSH1_k127_4524231_2 SAM-dependent K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 462.0
CSH1_k127_4524231_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 341.0
CSH1_k127_4524231_4 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.000000000000000000000000000000000000000000000000000000000001054 216.0
CSH1_k127_4524231_5 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000000000000000002395 181.0
CSH1_k127_4524231_6 bis(5'-adenosyl)-triphosphatase activity - - - 0.000000000000000000000000000000000000000000003438 171.0
CSH1_k127_4524231_7 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000153 174.0
CSH1_k127_4524231_8 signal peptide peptidase SppA, 36K type - - - 0.0000000000000000000000000000000000000000003764 175.0
CSH1_k127_4524231_9 Haloacid dehalogenase-like hydrolase K07025,K20866 - 3.1.3.10 0.0000000000000000000000000000001735 134.0
CSH1_k127_4530496_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 5.566e-208 655.0
CSH1_k127_4530496_1 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 508.0
CSH1_k127_4530496_2 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 443.0
CSH1_k127_4530496_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.0000000004453 61.0
CSH1_k127_4534418_0 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 375.0
CSH1_k127_4534418_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 298.0
CSH1_k127_4534418_2 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 290.0
CSH1_k127_4534418_3 diguanylate cyclase K13069 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000001065 267.0
CSH1_k127_4534418_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000031 258.0
CSH1_k127_4534418_5 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009332 256.0
CSH1_k127_4534418_6 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000001666 234.0
CSH1_k127_4534418_7 CHASE - - - 0.0000000000000000000000000000000000000000000000000000000000000002444 235.0
CSH1_k127_4534418_8 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000003186 217.0
CSH1_k127_4534418_9 PFAM AMMECR1 domain protein - - - 0.0000000000000000000000000000000000000000000209 169.0
CSH1_k127_4573923_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 3.984e-246 766.0
CSH1_k127_4573923_1 Pro-apoptotic serine protease - - - 2.426e-241 778.0
CSH1_k127_4573923_10 Protein of unknown function (DUF805) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000001852 180.0
CSH1_k127_4573923_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.00000000000000000000000000000000000000000000002445 177.0
CSH1_k127_4573923_12 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000003157 130.0
CSH1_k127_4573923_13 Haloacid dehalogenase-like hydrolase K07025,K20866 - 3.1.3.10 0.00000000000000000000000000000005352 132.0
CSH1_k127_4573923_14 - - - - 0.000000000000000000000000002673 115.0
CSH1_k127_4573923_15 - - - - 0.000000000000000000005545 100.0
CSH1_k127_4573923_2 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 603.0
CSH1_k127_4573923_3 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 603.0
CSH1_k127_4573923_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 488.0
CSH1_k127_4573923_5 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 437.0
CSH1_k127_4573923_6 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 430.0
CSH1_k127_4573923_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 331.0
CSH1_k127_4573923_8 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.000000000000000000000000000000000000000000000000000000000000003183 226.0
CSH1_k127_4573923_9 protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000000000001913 184.0
CSH1_k127_463617_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 604.0
CSH1_k127_463617_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 471.0
CSH1_k127_463617_2 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 302.0
CSH1_k127_463617_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000001019 186.0
CSH1_k127_463617_4 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.0000000000000000000002722 103.0
CSH1_k127_4649024_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1200.0
CSH1_k127_4649024_1 Outer membrane receptor proteins mostly Fe transport - - - 6.484e-216 701.0
CSH1_k127_4649024_10 Lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 307.0
CSH1_k127_4649024_11 hydrolase K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 310.0
CSH1_k127_4649024_12 Surface antigen variable number K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 317.0
CSH1_k127_4649024_13 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 294.0
CSH1_k127_4649024_14 maleylacetoacetate isomerase K01801 - 5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
CSH1_k127_4649024_15 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000064 268.0
CSH1_k127_4649024_16 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000007585 287.0
CSH1_k127_4649024_17 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 265.0
CSH1_k127_4649024_18 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000001202 262.0
CSH1_k127_4649024_19 Belongs to the ATCase OTCase family K09065,K13043 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000005727 252.0
CSH1_k127_4649024_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 5.573e-197 636.0
CSH1_k127_4649024_20 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001248 239.0
CSH1_k127_4649024_21 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000001435 226.0
CSH1_k127_4649024_22 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000009828 222.0
CSH1_k127_4649024_23 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000006406 205.0
CSH1_k127_4649024_24 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000003815 184.0
CSH1_k127_4649024_25 Thioesterase superfamily K19222 - 3.1.2.28 0.0000000000000000000000000000000000000000000006722 172.0
CSH1_k127_4649024_26 - - - - 0.0000000000000000000000000000000000008296 146.0
CSH1_k127_4649024_27 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000005622 137.0
CSH1_k127_4649024_28 - - - - 0.000000000000000000000000000002739 136.0
CSH1_k127_4649024_29 AsnC family transcriptional regulator - - - 0.0000000000000000000000000002684 116.0
CSH1_k127_4649024_3 COG1960 Acyl-CoA dehydrogenases K20035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 614.0
CSH1_k127_4649024_30 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000105 104.0
CSH1_k127_4649024_31 - - - - 0.00000000000000000007025 100.0
CSH1_k127_4649024_32 Autotransporter beta-domain - - - 0.00000006109 67.0
CSH1_k127_4649024_33 OmpA-like transmembrane domain - - - 0.000004518 54.0
CSH1_k127_4649024_4 Domain of unknown function (DUF4915) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 580.0
CSH1_k127_4649024_5 Protein of unknown function (DUF1329) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 535.0
CSH1_k127_4649024_6 (ABC) transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 426.0
CSH1_k127_4649024_7 Arginosuccinate synthase K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 410.0
CSH1_k127_4649024_8 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 349.0
CSH1_k127_4649024_9 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 381.0
CSH1_k127_4654571_0 Protein of unknown function (DUF3604) - - - 7.8e-322 995.0
CSH1_k127_4654571_1 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 370.0
CSH1_k127_4654571_2 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000742 243.0
CSH1_k127_4654571_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000007338 151.0
CSH1_k127_4654571_4 membrane K00389 - - 0.000000000000001328 78.0
CSH1_k127_4654571_5 CDP-archaeol synthase K19664 - 2.7.7.67 0.00000000005845 66.0
CSH1_k127_4672581_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit K14266 - 1.14.19.9 1.889e-262 814.0
CSH1_k127_4672581_1 COG1472 Beta-glucosidase-related glycosidases K05349 - 3.2.1.21 1.283e-208 664.0
CSH1_k127_4672581_2 Tryptophan halogenase K14266 - 1.14.19.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 545.0
CSH1_k127_4672581_3 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 406.0
CSH1_k127_4672581_4 SapC - - - 0.000000000000000000000000000000000000000000000000000000000000000000003147 243.0
CSH1_k127_4672581_5 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0000000000000000000000000000000000000000000000000000000007629 206.0
CSH1_k127_4703272_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 5.342e-316 982.0
CSH1_k127_4703272_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.226e-287 906.0
CSH1_k127_4703272_10 bacterial OsmY and nodulation domain K04065 - - 0.00000000000000000000000006367 114.0
CSH1_k127_4703272_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000008886 102.0
CSH1_k127_4703272_2 Participates in both transcription termination and antitermination K02600 - - 4.586e-221 694.0
CSH1_k127_4703272_3 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009781 592.0
CSH1_k127_4703272_4 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 531.0
CSH1_k127_4703272_5 PFAM fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 455.0
CSH1_k127_4703272_6 COG1448 Aspartate tyrosine aromatic aminotransferase K00813,K00832 - 2.6.1.1,2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 416.0
CSH1_k127_4703272_7 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000001208 276.0
CSH1_k127_4703272_8 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000115 147.0
CSH1_k127_4703272_9 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000001436 126.0
CSH1_k127_4708769_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002446 273.0
CSH1_k127_4708769_1 PQQ enzyme repeat - - - 0.00000000000000000000000000000000000000000000000000000001187 207.0
CSH1_k127_4708769_2 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000005748 196.0
CSH1_k127_4708769_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000003373 175.0
CSH1_k127_4711733_0 Exodeoxyribonuclease IX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002735 291.0
CSH1_k127_4711733_1 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001076 282.0
CSH1_k127_4711733_2 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.0000000000000000000000000000000000000000000000000004364 205.0
CSH1_k127_4711733_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001628 154.0
CSH1_k127_473607_0 FAD dependent oxidoreductase central domain - - - 2.044e-303 939.0
CSH1_k127_473607_1 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 2.99e-248 776.0
CSH1_k127_473607_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 599.0
CSH1_k127_473607_3 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 530.0
CSH1_k127_473607_4 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 353.0
CSH1_k127_473607_5 Alg9-like mannosyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001816 289.0
CSH1_k127_473607_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000002129 113.0
CSH1_k127_473607_7 - - - - 0.0000007624 60.0
CSH1_k127_4737437_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 531.0
CSH1_k127_4737437_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 523.0
CSH1_k127_4737437_10 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 325.0
CSH1_k127_4737437_11 PFAM Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 340.0
CSH1_k127_4737437_12 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 292.0
CSH1_k127_4737437_13 Lytic murein transglycosylase K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008747 296.0
CSH1_k127_4737437_14 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000003421 274.0
CSH1_k127_4737437_15 Nucleotidyl transferase K00966,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000007026 262.0
CSH1_k127_4737437_16 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000004897 254.0
CSH1_k127_4737437_17 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.000000000000000000000000000000000000000000000000000000000000000000001045 242.0
CSH1_k127_4737437_18 PFAM ApaG domain protein K06195 - - 0.00000000000000000000000000000000000000000000000005226 183.0
CSH1_k127_4737437_19 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000004712 180.0
CSH1_k127_4737437_2 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 500.0
CSH1_k127_4737437_20 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.000000000000000000000000000000000000000293 153.0
CSH1_k127_4737437_21 - - - - 0.0000000000000000000000000000000000001418 151.0
CSH1_k127_4737437_22 Universal stress protein K06149 - - 0.0000000000000000000000000001561 121.0
CSH1_k127_4737437_23 Belongs to the UPF0250 family K09158 - - 0.000000000000000000004408 104.0
CSH1_k127_4737437_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 466.0
CSH1_k127_4737437_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 424.0
CSH1_k127_4737437_5 FAD binding domain K00486 - 1.14.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 426.0
CSH1_k127_4737437_6 Belongs to the peptidase S51 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 400.0
CSH1_k127_4737437_7 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 411.0
CSH1_k127_4737437_8 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 385.0
CSH1_k127_4737437_9 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 361.0
CSH1_k127_4745816_0 peptidase K01354 - 3.4.21.83 2.604e-264 831.0
CSH1_k127_4745816_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 583.0
CSH1_k127_4745816_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 548.0
CSH1_k127_4745816_3 COG0501 Zn-dependent protease with chaperone function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 342.0
CSH1_k127_4745816_4 Peptidase family M3 K01284 - 3.4.15.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 282.0
CSH1_k127_4745816_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001648 259.0
CSH1_k127_4745816_6 - - - - 0.000000000273 67.0
CSH1_k127_4757379_0 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 343.0
CSH1_k127_4757379_1 LysR substrate binding domain K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000002989 232.0
CSH1_k127_4757379_2 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000004131 65.0
CSH1_k127_4757379_3 IstB-like ATP binding N-terminal - - - 0.0001288 50.0
CSH1_k127_4768621_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 7.397e-284 884.0
CSH1_k127_4768621_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 578.0
CSH1_k127_4768621_10 RHS Repeat - - - 0.0000000005357 67.0
CSH1_k127_4768621_2 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 502.0
CSH1_k127_4768621_3 PFAM Alcohol dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 391.0
CSH1_k127_4768621_4 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 386.0
CSH1_k127_4768621_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 362.0
CSH1_k127_4768621_6 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000008755 199.0
CSH1_k127_4768621_7 cytochrome - - - 0.00000000000000000000000000000000000000000000558 172.0
CSH1_k127_4768621_8 Protein of unknown function (DUF541) K09807 - - 0.0000000000000004232 87.0
CSH1_k127_4768621_9 NfeD-like C-terminal, partner-binding K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000001463 72.0
CSH1_k127_4778773_0 silver ion transport K07787 - - 0.0 1364.0
CSH1_k127_4778773_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 309.0
CSH1_k127_4778773_2 Isocitrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 290.0
CSH1_k127_4778773_3 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 302.0
CSH1_k127_4778773_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000005378 209.0
CSH1_k127_4778773_5 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000589 118.0
CSH1_k127_4788181_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 481.0
CSH1_k127_4788181_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 376.0
CSH1_k127_4788181_10 Sulfurtransferase - - - 0.000000000000000000000000003094 117.0
CSH1_k127_4788181_2 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 359.0
CSH1_k127_4788181_3 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000002099 237.0
CSH1_k127_4788181_4 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 0.00000000000000000000000000000000000000000000000000000088 199.0
CSH1_k127_4788181_5 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000007234 194.0
CSH1_k127_4788181_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000002511 171.0
CSH1_k127_4788181_7 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000001107 174.0
CSH1_k127_4788181_8 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000002475 121.0
CSH1_k127_4788181_9 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 - 0.00000000000000000000000000005574 124.0
CSH1_k127_4809188_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.461e-315 979.0
CSH1_k127_4809188_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 8.348e-290 906.0
CSH1_k127_4809188_10 von Willebrand factor (VWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 323.0
CSH1_k127_4809188_11 Lecithin:cholesterol acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 317.0
CSH1_k127_4809188_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 305.0
CSH1_k127_4809188_13 COG0811 Biopolymer transport proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 291.0
CSH1_k127_4809188_14 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004115 285.0
CSH1_k127_4809188_15 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001232 261.0
CSH1_k127_4809188_16 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004058 258.0
CSH1_k127_4809188_17 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000489 237.0
CSH1_k127_4809188_18 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000003956 219.0
CSH1_k127_4809188_19 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000005368 206.0
CSH1_k127_4809188_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 3.904e-220 692.0
CSH1_k127_4809188_20 PFAM histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000000000001122 187.0
CSH1_k127_4809188_21 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000001854 198.0
CSH1_k127_4809188_22 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000001865 183.0
CSH1_k127_4809188_23 - - - - 0.0000000000000000000000000000000000000000000004283 181.0
CSH1_k127_4809188_24 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000003576 171.0
CSH1_k127_4809188_25 - - - - 0.0000000000000000000000000000000000000000003176 177.0
CSH1_k127_4809188_26 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000008916 118.0
CSH1_k127_4809188_27 - - - - 0.0000000000000000001095 103.0
CSH1_k127_4809188_28 - - - - 0.0000000000000001006 94.0
CSH1_k127_4809188_29 - - - - 0.000000000000002836 85.0
CSH1_k127_4809188_3 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 501.0
CSH1_k127_4809188_30 - - - - 0.000000000001107 80.0
CSH1_k127_4809188_4 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 465.0
CSH1_k127_4809188_5 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 447.0
CSH1_k127_4809188_6 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 393.0
CSH1_k127_4809188_7 Secreted protein, containing von Willebrand factor (VWF) type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 368.0
CSH1_k127_4809188_8 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 349.0
CSH1_k127_4809188_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 319.0
CSH1_k127_4850649_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 8.303e-233 732.0
CSH1_k127_4850649_1 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 1.592e-226 720.0
CSH1_k127_4850649_2 Sulfatase K01130 - 3.1.6.1 1.02e-216 677.0
CSH1_k127_4850649_3 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 350.0
CSH1_k127_4850649_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001884 279.0
CSH1_k127_4850649_5 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000001377 184.0
CSH1_k127_4850649_6 electron transfer activity K03737,K05337 - 1.2.7.1 0.00005051 57.0
CSH1_k127_4863609_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 2.384e-259 807.0
CSH1_k127_4863609_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 1.151e-250 782.0
CSH1_k127_4863609_10 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 554.0
CSH1_k127_4863609_11 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 383.0
CSH1_k127_4863609_12 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 339.0
CSH1_k127_4863609_13 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 328.0
CSH1_k127_4863609_14 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 284.0
CSH1_k127_4863609_15 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000515 270.0
CSH1_k127_4863609_16 Putative 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008225 250.0
CSH1_k127_4863609_17 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003761 235.0
CSH1_k127_4863609_18 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000000009401 220.0
CSH1_k127_4863609_19 PFAM RDD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000003932 216.0
CSH1_k127_4863609_2 Cytochrome c-type biogenesis protein CcmF C-terminal - - - 1.109e-243 769.0
CSH1_k127_4863609_20 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000006717 192.0
CSH1_k127_4863609_21 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000000000000000000002874 186.0
CSH1_k127_4863609_22 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015232,GO:0015886,GO:0022857,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:1901678 3.6.3.41 0.0000000000000000000000000000000000000000000000002679 184.0
CSH1_k127_4863609_23 Water Stress and Hypersensitive response - - - 0.0000000000000000000000000000000000000000000000003516 181.0
CSH1_k127_4863609_24 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00127 - - 0.000000000000000000000000000000000000000000000002047 178.0
CSH1_k127_4863609_25 CcmE - - - 0.0000000000000000000000000000000000000000000001713 174.0
CSH1_k127_4863609_26 FCD - - - 0.0000000000000000000000000000000000000000007481 170.0
CSH1_k127_4863609_27 MaoC like domain - - - 0.0000000000000000000000000000000000000001165 164.0
CSH1_k127_4863609_28 Cytochrome C biogenesis K02200 - - 0.00000000000000000000000000000000000002078 158.0
CSH1_k127_4863609_29 Tyrosine phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000006874 147.0
CSH1_k127_4863609_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 2.259e-242 760.0
CSH1_k127_4863609_30 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000003521 138.0
CSH1_k127_4863609_31 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.0000000000000000000000000000005106 132.0
CSH1_k127_4863609_32 Cupin domain - - - 0.0000000000000000000000000000008305 128.0
CSH1_k127_4863609_33 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000617 101.0
CSH1_k127_4863609_34 - - - - 0.00000000000000000001311 101.0
CSH1_k127_4863609_35 - - - - 0.0000000000000000002645 97.0
CSH1_k127_4863609_36 Periplasmic or secreted lipoprotein K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.000000000000000000671 94.0
CSH1_k127_4863609_37 - - - - 0.000000000000000006873 93.0
CSH1_k127_4863609_38 Belongs to the UPF0270 family K09898 - - 0.00000000000006359 76.0
CSH1_k127_4863609_39 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000003815 50.0
CSH1_k127_4863609_4 protease with the C-terminal PDZ domain - - - 2.394e-226 720.0
CSH1_k127_4863609_5 COG0457 FOG TPR repeat - - - 8.777e-194 615.0
CSH1_k127_4863609_6 Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 599.0
CSH1_k127_4863609_7 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 630.0
CSH1_k127_4863609_8 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 595.0
CSH1_k127_4863609_9 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 563.0
CSH1_k127_4877354_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 599.0
CSH1_k127_4877354_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 546.0
CSH1_k127_4877354_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 430.0
CSH1_k127_4877354_3 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 361.0
CSH1_k127_4877354_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 328.0
CSH1_k127_4877354_5 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 318.0
CSH1_k127_4877354_6 PDZ domain - - - 0.000000000000000000000000000001233 134.0
CSH1_k127_4877354_7 Preprotein translocase subunit YajC K03210 - - 0.00000000000000000000000000002791 134.0
CSH1_k127_4913798_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1419.0
CSH1_k127_4913798_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.442e-204 654.0
CSH1_k127_4913798_10 -acetyltransferase - - - 0.00000000000000000006133 96.0
CSH1_k127_4913798_11 Membrane protein implicated in regulation of membrane protease activity - - - 0.0000000000000000006789 88.0
CSH1_k127_4913798_2 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 404.0
CSH1_k127_4913798_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 401.0
CSH1_k127_4913798_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 325.0
CSH1_k127_4913798_5 PFAM CBS domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 314.0
CSH1_k127_4913798_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003199 273.0
CSH1_k127_4913798_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000001549 199.0
CSH1_k127_4913798_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000002389 153.0
CSH1_k127_4913798_9 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 0.00000000000000000000000000000000008948 137.0
CSH1_k127_493429_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1039.0
CSH1_k127_493429_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 7.81e-308 956.0
CSH1_k127_493429_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008125 280.0
CSH1_k127_493429_11 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002139 259.0
CSH1_k127_493429_12 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002572 255.0
CSH1_k127_493429_13 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000004387 174.0
CSH1_k127_493429_14 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000003266 149.0
CSH1_k127_493429_15 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000001169 80.0
CSH1_k127_493429_16 methyltransferase - - - 0.0001278 45.0
CSH1_k127_493429_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.371e-278 867.0
CSH1_k127_493429_3 Cysteine-rich domain - - - 9.729e-201 634.0
CSH1_k127_493429_4 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 404.0
CSH1_k127_493429_5 lysine 2,3-aminomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 393.0
CSH1_k127_493429_6 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 350.0
CSH1_k127_493429_7 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 310.0
CSH1_k127_493429_8 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 302.0
CSH1_k127_493429_9 cyclic-guanylate-specific phosphodiesterase activity K21025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003011 299.0
CSH1_k127_4955118_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 540.0
CSH1_k127_4955118_1 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 467.0
CSH1_k127_4955118_2 Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000005609 164.0
CSH1_k127_500975_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 545.0
CSH1_k127_500975_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 512.0
CSH1_k127_500975_10 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000001766 151.0
CSH1_k127_500975_11 amino acid K03294 - - 0.0000000000000000000000000000000007626 133.0
CSH1_k127_500975_12 protein conserved in bacteria - - - 0.000000000000000000000000000005922 129.0
CSH1_k127_500975_13 protein conserved in bacteria K15539 - - 0.00000000000000000001346 105.0
CSH1_k127_500975_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 458.0
CSH1_k127_500975_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 447.0
CSH1_k127_500975_4 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 323.0
CSH1_k127_500975_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004704 285.0
CSH1_k127_500975_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000007528 227.0
CSH1_k127_500975_7 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000004491 228.0
CSH1_k127_500975_8 Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000005932 179.0
CSH1_k127_500975_9 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 - - 0.0000000000000000000000000000000000000000002953 160.0
CSH1_k127_5115351_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 2.248e-256 804.0
CSH1_k127_5115351_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 9.558e-245 768.0
CSH1_k127_5115351_10 Acyl CoA binding protein - - - 0.00000000000000000000002723 102.0
CSH1_k127_5115351_2 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 482.0
CSH1_k127_5115351_3 Major facilitator superfamily K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 447.0
CSH1_k127_5115351_4 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 286.0
CSH1_k127_5115351_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001022 268.0
CSH1_k127_5115351_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000004522 279.0
CSH1_k127_5115351_7 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000008326 218.0
CSH1_k127_5115351_8 Belongs to the MtfA family K09933 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000005594 207.0
CSH1_k127_5115351_9 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000001508 169.0
CSH1_k127_5137090_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K03852 - 2.3.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 536.0
CSH1_k127_5137090_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 398.0
CSH1_k127_5137090_2 Periplasmic solute binding protein K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 353.0
CSH1_k127_5137090_3 ABC-3 protein K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008614 270.0
CSH1_k127_5137090_4 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000002599 155.0
CSH1_k127_5174863_0 Ring hydroxylating alpha subunit (catalytic domain) K08689 - 1.14.12.18 8.179e-220 692.0
CSH1_k127_5174863_1 TonB dependent receptor - - - 2.595e-202 658.0
CSH1_k127_5174863_2 nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000003429 156.0
CSH1_k127_5174863_3 MaoC like domain - - - 0.000000000000000000000000000000000000127 148.0
CSH1_k127_5174863_4 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000006695 107.0
CSH1_k127_5174863_5 choline kinase involved in LPS biosynthesis - - - 0.000000000000000000001377 106.0
CSH1_k127_5174863_6 YKOF-related Family - - - 0.0000000000000000004558 89.0
CSH1_k127_520492_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.067e-282 876.0
CSH1_k127_520492_1 Belongs to the glycosyl hydrolase 57 family - - - 4.335e-255 792.0
CSH1_k127_5230444_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 6.081e-290 896.0
CSH1_k127_5230444_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 5.904e-228 718.0
CSH1_k127_5230444_10 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000002416 198.0
CSH1_k127_5230444_11 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000005804 180.0
CSH1_k127_5230444_12 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000003241 159.0
CSH1_k127_5230444_13 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000003266 145.0
CSH1_k127_5230444_14 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.0000000000000000000000508 104.0
CSH1_k127_5230444_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 562.0
CSH1_k127_5230444_3 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 536.0
CSH1_k127_5230444_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 445.0
CSH1_k127_5230444_5 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 423.0
CSH1_k127_5230444_6 acyl-CoA synthetase family member 2 K14760,K20798 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0006732,GO:0006766,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009507,GO:0009526,GO:0009536,GO:0009941,GO:0009987,GO:0016020,GO:0031090,GO:0031903,GO:0031967,GO:0031969,GO:0031975,GO:0042170,GO:0042180,GO:0042181,GO:0042372,GO:0042374,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0098588,GO:0098805,GO:1901576,GO:1901661,GO:1901663 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 424.0
CSH1_k127_5230444_7 homocysteine K00297,K00547 GO:0003674,GO:0003824,GO:0005488,GO:0006575,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008270,GO:0008757,GO:0008898,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033477,GO:0033554,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:1901564 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 379.0
CSH1_k127_5230444_8 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006116 262.0
CSH1_k127_5230444_9 sulfuric ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000001441 206.0
CSH1_k127_5233579_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0 1201.0
CSH1_k127_5233579_1 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 614.0
CSH1_k127_5233579_10 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000006457 166.0
CSH1_k127_5233579_2 Sodium:alanine symporter family K03310 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 591.0
CSH1_k127_5233579_3 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 569.0
CSH1_k127_5233579_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 561.0
CSH1_k127_5233579_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 527.0
CSH1_k127_5233579_6 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 317.0
CSH1_k127_5233579_7 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000000000000000000000000004165 220.0
CSH1_k127_5233579_8 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002502 207.0
CSH1_k127_5233579_9 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000004445 211.0
CSH1_k127_5234919_0 Formate dehydrogenase alpha subunit K00123 - 1.17.1.9 4.183e-242 753.0
CSH1_k127_5234919_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 586.0
CSH1_k127_5234919_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 375.0
CSH1_k127_5234919_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000001857 235.0
CSH1_k127_5234919_4 formate dehydrogenase K00126 - 1.17.1.9 0.000000000008116 70.0
CSH1_k127_5247800_0 PQQ enzyme repeat K17760 - 1.1.9.1 5.853e-275 881.0
CSH1_k127_5247800_1 COG2826 Transposase and inactivated derivatives, IS30 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 448.0
CSH1_k127_5247800_2 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 434.0
CSH1_k127_5247800_3 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 381.0
CSH1_k127_5256854_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1128.0
CSH1_k127_5256854_1 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1099.0
CSH1_k127_5256854_10 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 417.0
CSH1_k127_5256854_11 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 422.0
CSH1_k127_5256854_12 PFAM ABC transporter K05847 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 409.0
CSH1_k127_5256854_13 Protein of unknown function (DUF2855) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 399.0
CSH1_k127_5256854_14 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 364.0
CSH1_k127_5256854_15 ABC-type proline glycine betaine transport systems, permease component K05846 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 367.0
CSH1_k127_5256854_16 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 345.0
CSH1_k127_5256854_17 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009851 350.0
CSH1_k127_5256854_18 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 334.0
CSH1_k127_5256854_19 PAC sensor-containing diguanylate cyclase phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 344.0
CSH1_k127_5256854_2 FAD dependent oxidoreductase central domain - - - 5.31e-304 970.0
CSH1_k127_5256854_20 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0033554,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071214,GO:0071470,GO:0071474,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0104004 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 346.0
CSH1_k127_5256854_21 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 311.0
CSH1_k127_5256854_22 Binding-protein-dependent transport system inner membrane component K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 304.0
CSH1_k127_5256854_23 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002142 267.0
CSH1_k127_5256854_24 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003274 257.0
CSH1_k127_5256854_25 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002398 276.0
CSH1_k127_5256854_26 [2Fe-2S] binding domain K07302,K13483 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000757 246.0
CSH1_k127_5256854_27 guanyl-nucleotide exchange factor activity K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000102 247.0
CSH1_k127_5256854_28 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000216 240.0
CSH1_k127_5256854_29 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000006991 228.0
CSH1_k127_5256854_3 PHP domain protein - - - 1.752e-249 811.0
CSH1_k127_5256854_30 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000001597 219.0
CSH1_k127_5256854_31 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000001673 221.0
CSH1_k127_5256854_32 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000004849 231.0
CSH1_k127_5256854_33 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000001883 195.0
CSH1_k127_5256854_34 Protein of unknown function (DUF2799) - - - 0.00000000000000000000000007026 124.0
CSH1_k127_5256854_35 Peptidase inhibitor I9 - - - 0.00000000000000000149 100.0
CSH1_k127_5256854_36 Acyl-CoA synthetase K01895 - 6.2.1.1 0.000000000000000002491 90.0
CSH1_k127_5256854_38 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000003604 68.0
CSH1_k127_5256854_39 intein-mediated protein splicing K06224,K11990,K16669 GO:0003002,GO:0003674,GO:0003824,GO:0004175,GO:0005102,GO:0005488,GO:0005496,GO:0005515,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007267,GO:0007275,GO:0007350,GO:0007365,GO:0007367,GO:0007389,GO:0008150,GO:0008152,GO:0008233,GO:0008289,GO:0009790,GO:0009880,GO:0009987,GO:0010467,GO:0015485,GO:0016020,GO:0016485,GO:0016540,GO:0016787,GO:0019538,GO:0023052,GO:0032501,GO:0032502,GO:0032934,GO:0035282,GO:0036094,GO:0043170,GO:0043178,GO:0044238,GO:0044464,GO:0048856,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0140096,GO:1901564 - 0.0000001917 64.0
CSH1_k127_5256854_4 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 4.234e-232 728.0
CSH1_k127_5256854_40 OmpA-like transmembrane domain - - - 0.000002392 58.0
CSH1_k127_5256854_41 - - - - 0.0005494 53.0
CSH1_k127_5256854_42 HAF family - - - 0.0007433 52.0
CSH1_k127_5256854_5 trimethylamine methyltransferase K14083 - 2.1.1.250 6.086e-215 679.0
CSH1_k127_5256854_6 Major Facilitator Superfamily K02445,K07783 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 596.0
CSH1_k127_5256854_7 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 479.0
CSH1_k127_5256854_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 439.0
CSH1_k127_5256854_9 Aminotransferase, class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 442.0
CSH1_k127_5275360_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 3.23e-293 920.0
CSH1_k127_5275360_1 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 4.028e-230 736.0
CSH1_k127_5275360_10 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 401.0
CSH1_k127_5275360_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 292.0
CSH1_k127_5275360_12 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006074 257.0
CSH1_k127_5275360_13 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000001505 195.0
CSH1_k127_5275360_14 UTRA K03710 GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000002917 194.0
CSH1_k127_5275360_15 Tetratricopeptide repeat - - - 0.00000000000006813 79.0
CSH1_k127_5275360_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000377 70.0
CSH1_k127_5275360_17 VanZ like family - - - 0.00000000002929 75.0
CSH1_k127_5275360_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000009454 68.0
CSH1_k127_5275360_2 PFAM peptidase M2, peptidyl-dipeptidase A K01283 - 3.4.15.1 5.467e-225 714.0
CSH1_k127_5275360_3 COG3104 Dipeptide tripeptide permease K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 616.0
CSH1_k127_5275360_4 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 614.0
CSH1_k127_5275360_5 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 595.0
CSH1_k127_5275360_6 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 533.0
CSH1_k127_5275360_7 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 519.0
CSH1_k127_5275360_8 TIGRFAM amino acid peptide transporter (Peptide H symporter), bacterial K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 477.0
CSH1_k127_5275360_9 COG3104 Dipeptide tripeptide permease K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008093 456.0
CSH1_k127_5275831_0 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA K06445 - - 6.818e-293 920.0
CSH1_k127_5275831_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 417.0
CSH1_k127_5275831_2 lytic transglycosylase activity K03194 - - 0.00000000000000004634 95.0
CSH1_k127_5289920_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 3.935e-272 861.0
CSH1_k127_5289920_1 Belongs to the UPF0061 (SELO) family K08997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 584.0
CSH1_k127_5289920_10 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000003599 108.0
CSH1_k127_5289920_11 Putative DNA-binding domain - - - 0.0000000000000000000001386 108.0
CSH1_k127_5289920_12 Acid phosphatase homologues - - - 0.0000000000000000006623 98.0
CSH1_k127_5289920_13 Predicted integral membrane protein (DUF2282) - - - 0.000000000000000006907 86.0
CSH1_k127_5289920_2 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 571.0
CSH1_k127_5289920_3 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 324.0
CSH1_k127_5289920_4 Arginase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 295.0
CSH1_k127_5289920_5 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005103 249.0
CSH1_k127_5289920_6 Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000001074 240.0
CSH1_k127_5289920_7 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000001171 192.0
CSH1_k127_5289920_8 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000000000000000000000003646 163.0
CSH1_k127_5289920_9 protein conserved in bacteria - - - 0.000000000000000000000000003369 119.0
CSH1_k127_5292667_0 Glutamine synthetase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 612.0
CSH1_k127_5292667_1 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0034024,GO:0034641,GO:0042402,GO:0044106,GO:0044237,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 479.0
CSH1_k127_5292667_2 FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 468.0
CSH1_k127_5292667_3 Glutamine K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 306.0
CSH1_k127_5292667_4 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000003364 228.0
CSH1_k127_5292667_5 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000006289 210.0
CSH1_k127_5299253_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 544.0
CSH1_k127_5299253_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006520,GO:0006553,GO:0006563,GO:0006564,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046394,GO:0046451,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901615,GO:1901617 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 497.0
CSH1_k127_5299253_2 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 419.0
CSH1_k127_5299253_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 346.0
CSH1_k127_5307335_0 Nickel-dependent hydrogenase K06281 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 6.386e-313 965.0
CSH1_k127_5307335_1 small subunit K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 584.0
CSH1_k127_5307335_2 Prokaryotic cytochrome b561 K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005142 262.0
CSH1_k127_5307335_3 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000006046 226.0
CSH1_k127_5307335_4 Protein of unknown function, DUF481 - - - 0.0000000000000000000000000000000002521 141.0
CSH1_k127_5329548_0 Bacterial protein of unknown function (DUF839) K07093 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 423.0
CSH1_k127_5329548_1 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 340.0
CSH1_k127_5448852_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003364 282.0
CSH1_k127_5448852_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000001283 121.0
CSH1_k127_5448852_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000006567 100.0
CSH1_k127_5486419_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 587.0
CSH1_k127_5486419_1 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 505.0
CSH1_k127_5486419_10 - - - - 0.000000000000000006095 93.0
CSH1_k127_5486419_2 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 417.0
CSH1_k127_5486419_3 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 358.0
CSH1_k127_5486419_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 321.0
CSH1_k127_5486419_5 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.000000000000000000000000000000000000000000000000000005511 197.0
CSH1_k127_5486419_6 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000001136 197.0
CSH1_k127_5486419_7 Iron--sulfur cluster insertion protein erpA K15724 - - 0.00000000000000000000000000000000000000000000000002023 182.0
CSH1_k127_5486419_8 - - - - 0.000000000000000000000000000000000000002187 154.0
CSH1_k127_5486419_9 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000002839 132.0
CSH1_k127_5504500_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1052.0
CSH1_k127_5504500_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.055e-295 915.0
CSH1_k127_5504500_10 Sigma E regulatory protein, MucB RseB K03598 - - 0.0000000000000000000000000000000000000000000005799 184.0
CSH1_k127_5504500_11 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000003317 176.0
CSH1_k127_5504500_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000001669 115.0
CSH1_k127_5504500_13 Diguanylate cyclase - - - 0.00000000000007544 82.0
CSH1_k127_5504500_14 Domain of unknown function (DUF4845) - - - 0.0000000009961 64.0
CSH1_k127_5504500_15 PFAM glutaredoxin 2 - - - 0.00000009611 60.0
CSH1_k127_5504500_16 Anti sigma-E protein RseA, N-terminal domain - - - 0.0000006181 61.0
CSH1_k127_5504500_17 Positive regulator of sigma(E), RseC/MucC - - - 0.000001247 56.0
CSH1_k127_5504500_2 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 479.0
CSH1_k127_5504500_3 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 372.0
CSH1_k127_5504500_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 324.0
CSH1_k127_5504500_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 318.0
CSH1_k127_5504500_6 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 322.0
CSH1_k127_5504500_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000001478 267.0
CSH1_k127_5504500_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000001815 230.0
CSH1_k127_5504500_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000001823 230.0
CSH1_k127_5533678_0 Belongs to the aldehyde dehydrogenase family K09472,K12254 - 1.2.1.54,1.2.1.99 3.135e-214 676.0
CSH1_k127_5533678_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 5.099e-213 670.0
CSH1_k127_5533678_10 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007141 248.0
CSH1_k127_5533678_11 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000001453 171.0
CSH1_k127_5533678_12 PFAM Cold-shock protein, DNA-binding - - - 0.00000000000000000000000000009634 122.0
CSH1_k127_5533678_13 transcriptional regulator K06995 - - 0.00000000000000000000000004724 114.0
CSH1_k127_5533678_2 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 551.0
CSH1_k127_5533678_3 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 520.0
CSH1_k127_5533678_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 478.0
CSH1_k127_5533678_5 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 444.0
CSH1_k127_5533678_6 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 429.0
CSH1_k127_5533678_7 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 392.0
CSH1_k127_5533678_8 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 374.0
CSH1_k127_5533678_9 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 325.0
CSH1_k127_5563412_0 AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 457.0
CSH1_k127_5563412_1 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 312.0
CSH1_k127_5563412_2 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 300.0
CSH1_k127_5563412_3 Protein conserved in bacteria K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 288.0
CSH1_k127_5563412_4 KR domain K05296 - 1.1.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000005297 269.0
CSH1_k127_5563412_5 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001669 263.0
CSH1_k127_5563412_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000006178 166.0
CSH1_k127_5563412_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000033 162.0
CSH1_k127_5563412_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000003923 114.0
CSH1_k127_5666501_0 Dak2 K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 479.0
CSH1_k127_5666501_1 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 447.0
CSH1_k127_5666501_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 329.0
CSH1_k127_5666501_3 Serine aminopeptidase, S33 K01055,K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000044 263.0
CSH1_k127_5666501_4 Protein of unknown function (DUF3667) - - - 0.000000000000000000000000000007228 135.0
CSH1_k127_5666501_5 Domain of unknown function (DUF4286) - - - 0.0000000000000008955 91.0
CSH1_k127_5666501_6 Type II secretion system protein B - - - 0.00000000000005853 81.0
CSH1_k127_5695827_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1406.0
CSH1_k127_5695827_1 Glycine cleavage T-protein C-terminal barrel domain K00302 - 1.5.3.1 0.0 1298.0
CSH1_k127_5695827_10 Sarcosine oxidase, gamma subunit family K00305 - 1.5.3.1 0.00000000000000000000000000000000000000003734 158.0
CSH1_k127_5695827_11 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000002904 160.0
CSH1_k127_5695827_12 Sarcosine oxidase delta subunit K00304 - 1.5.3.1 0.00000000000000000000000000000000000003752 144.0
CSH1_k127_5695827_13 LysR substrate binding domain - - - 0.0001318 46.0
CSH1_k127_5695827_2 FAD dependent oxidoreductase central domain - - - 0.0 1139.0
CSH1_k127_5695827_3 Belongs to the GcvT family K00315 - 1.5.8.4 0.0 1045.0
CSH1_k127_5695827_4 Belongs to the BCCT transporter (TC 2.A.15) family K03451 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 620.0
CSH1_k127_5695827_5 sarcosine oxidase, beta subunit K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 542.0
CSH1_k127_5695827_6 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 543.0
CSH1_k127_5695827_7 Aldolase K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 425.0
CSH1_k127_5695827_8 PFAM helix-turn-helix- domain containing protein, AraC type K21826 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 402.0
CSH1_k127_5695827_9 Serine aminopeptidase, S33 K09023 - - 0.000000000000000000000000000000000000000000000000000000001368 224.0
CSH1_k127_5716560_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1546.0
CSH1_k127_5716560_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 477.0
CSH1_k127_5716560_10 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000000125 177.0
CSH1_k127_5716560_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000004303 135.0
CSH1_k127_5716560_2 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 392.0
CSH1_k127_5716560_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 326.0
CSH1_k127_5716560_4 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002752 249.0
CSH1_k127_5716560_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002079 239.0
CSH1_k127_5716560_6 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000004058 227.0
CSH1_k127_5716560_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000005416 207.0
CSH1_k127_5716560_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000001387 208.0
CSH1_k127_5716560_9 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000006078 198.0
CSH1_k127_5746353_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 517.0
CSH1_k127_5746353_1 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 309.0
CSH1_k127_5746353_2 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000000000000004171 185.0
CSH1_k127_5746353_3 KR domain K07124 - - 0.00000000000000000000000000000000002536 145.0
CSH1_k127_5746353_4 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0007563 44.0
CSH1_k127_5798465_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K12508 - 6.2.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 627.0
CSH1_k127_5798465_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 546.0
CSH1_k127_5798465_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002336 242.0
CSH1_k127_5798465_11 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000001166 219.0
CSH1_k127_5798465_12 Cytochrome P450 K15468 - - 0.0000000000000000000000000000000000000000000000000000000002049 215.0
CSH1_k127_5798465_13 membrane - - - 0.0000000000000000000000000000000000000000000000002315 191.0
CSH1_k127_5798465_14 MaoC like domain - - - 0.000000000000000000000000000000000000000000000002006 187.0
CSH1_k127_5798465_15 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.00000000000000000000000000000000003057 140.0
CSH1_k127_5798465_16 TonB dependent receptor K02014 - - 0.000007015 52.0
CSH1_k127_5798465_2 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 534.0
CSH1_k127_5798465_3 PFAM AMP-dependent synthetase and ligase K15868 - 6.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 524.0
CSH1_k127_5798465_4 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 423.0
CSH1_k127_5798465_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 385.0
CSH1_k127_5798465_6 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 382.0
CSH1_k127_5798465_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 342.0
CSH1_k127_5798465_8 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 307.0
CSH1_k127_5798465_9 PFAM alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001043 289.0
CSH1_k127_5820480_0 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 591.0
CSH1_k127_5820480_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 450.0
CSH1_k127_5820480_2 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 315.0
CSH1_k127_5820480_3 COG0625 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002588 257.0
CSH1_k127_5820480_4 PFAM catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000976 184.0
CSH1_k127_5820480_5 glutathione s-transferase - - - 0.0000000000000000000000000000000000000008119 153.0
CSH1_k127_5820480_6 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000004693 107.0
CSH1_k127_5820480_7 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000000000001077 96.0
CSH1_k127_5820480_8 Rieske-like [2Fe-2S] domain - - - 0.0000000000000000003047 92.0
CSH1_k127_5831528_0 Ammonium Transporter K03320 - - 2.195e-198 629.0
CSH1_k127_5831528_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 341.0
CSH1_k127_5831528_10 Response regulator of the LytR AlgR family K08083 - - 0.000000000000000000000000000000000000000000000000000000000000001079 231.0
CSH1_k127_5831528_11 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000003521 208.0
CSH1_k127_5831528_12 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000001737 184.0
CSH1_k127_5831528_13 enzyme of heme biosynthesis K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000002722 161.0
CSH1_k127_5831528_14 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000002699 141.0
CSH1_k127_5831528_15 SMART CoA-binding domain protein K06929 - - 0.0000000000000000000000000000007382 134.0
CSH1_k127_5831528_16 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.000000000000000000000003279 113.0
CSH1_k127_5831528_17 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000338 106.0
CSH1_k127_5831528_18 Membrane fusogenic activity K09806 - - 0.00000000000000000004235 94.0
CSH1_k127_5831528_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 341.0
CSH1_k127_5831528_3 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 327.0
CSH1_k127_5831528_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 320.0
CSH1_k127_5831528_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 314.0
CSH1_k127_5831528_6 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002138 284.0
CSH1_k127_5831528_7 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001103 260.0
CSH1_k127_5831528_8 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001148 276.0
CSH1_k127_5831528_9 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003449 254.0
CSH1_k127_5855830_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 4.042e-201 640.0
CSH1_k127_5855830_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.072e-196 622.0
CSH1_k127_5855830_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 335.0
CSH1_k127_5855830_3 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000003194 231.0
CSH1_k127_5855830_4 Thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000000000000005085 214.0
CSH1_k127_5855830_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001338 204.0
CSH1_k127_5855830_6 KR domain - - - 0.000000000000000000000000000000000000000000000000007084 191.0
CSH1_k127_5855830_7 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000004514 168.0
CSH1_k127_5855830_8 Sterol-binding domain protein K03690 - - 0.000000000000000000000004062 113.0
CSH1_k127_5855830_9 (GGDEF) domain K21023 - 2.7.7.65 0.0000006632 58.0
CSH1_k127_5892692_0 C-terminal region of aryl-sulfatase - - - 1.09e-321 991.0
CSH1_k127_5892692_1 Protein of unknown function (DUF3604) - - - 5.326e-217 676.0
CSH1_k127_5892692_2 Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithine K00821,K09251 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575 2.6.1.11,2.6.1.17,2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 503.0
CSH1_k127_5892692_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 374.0
CSH1_k127_5892692_4 DNA-binding transcription factor activity K14057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001144 282.0
CSH1_k127_5892692_5 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001399 262.0
CSH1_k127_5892692_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005266 235.0
CSH1_k127_5892692_7 Belongs to the Dps family K04047 - - 0.00000000000000000000000004204 108.0
CSH1_k127_5892692_8 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000001066 53.0
CSH1_k127_5913104_0 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 538.0
CSH1_k127_5913104_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 342.0
CSH1_k127_5913104_2 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 337.0
CSH1_k127_5913104_3 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000003371 198.0
CSH1_k127_5913104_4 Domain of unknown function (DUF4377) - - - 0.0000000000000000000000000000000000000000001 175.0
CSH1_k127_5913104_5 lipoprotein NlpE involved in copper resistance - - - 0.00000000000000000000000006969 121.0
CSH1_k127_5925168_0 Cation transporting ATPase, C-terminus - - - 2.143e-243 781.0
CSH1_k127_5925168_1 receptor K02014 - - 3.661e-242 768.0
CSH1_k127_5925168_10 PFAM fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 454.0
CSH1_k127_5925168_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 367.0
CSH1_k127_5925168_12 Alternative locus ID - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 353.0
CSH1_k127_5925168_13 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 306.0
CSH1_k127_5925168_14 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001002 280.0
CSH1_k127_5925168_15 reductase K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000006226 242.0
CSH1_k127_5925168_16 Serine aminopeptidase, S33 K01048 GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000009077 224.0
CSH1_k127_5925168_17 - - - - 0.00000000000000000000000000000000000000000000000000006592 194.0
CSH1_k127_5925168_18 YhhN family - - - 0.0000000000000000000000000000000000000000002564 167.0
CSH1_k127_5925168_19 - - - - 0.000000000000000000000000000000000000000004167 161.0
CSH1_k127_5925168_2 Protein of unknown function (DUF1343) - - - 5.447e-212 668.0
CSH1_k127_5925168_20 DNA polymerase III, epsilon K02342 - 2.7.7.7 0.000000000000000000000000000000000000006035 155.0
CSH1_k127_5925168_21 - - - - 0.00000000000000000000000000000000002595 140.0
CSH1_k127_5925168_22 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000006469 135.0
CSH1_k127_5925168_23 - - - - 0.000000000000000000000000000000001252 137.0
CSH1_k127_5925168_24 response to heat K03668,K06079,K09914 - - 0.0000000000000001095 91.0
CSH1_k127_5925168_25 Outer membrane protein W K07275 - - 0.0000001794 61.0
CSH1_k127_5925168_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.332e-210 666.0
CSH1_k127_5925168_4 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly - - - 3.552e-210 660.0
CSH1_k127_5925168_5 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 1.127e-195 623.0
CSH1_k127_5925168_6 Lytic murein transglycosylase K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 572.0
CSH1_k127_5925168_7 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 566.0
CSH1_k127_5925168_8 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 520.0
CSH1_k127_5925168_9 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 456.0
CSH1_k127_6058_0 transporter - - - 4.379e-263 827.0
CSH1_k127_6058_1 Belongs to the TPP enzyme family K04103 - 4.1.1.74 2.965e-212 673.0
CSH1_k127_6058_10 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000001176 139.0
CSH1_k127_6058_11 PFAM Membrane protein of K08972 - - 0.00000000000000000000000008784 116.0
CSH1_k127_6058_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000001929 113.0
CSH1_k127_6058_2 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 463.0
CSH1_k127_6058_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 338.0
CSH1_k127_6058_4 Biopolymer transporter ExbB K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005101 244.0
CSH1_k127_6058_5 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000006618 218.0
CSH1_k127_6058_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000001697 207.0
CSH1_k127_6058_7 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000001509 202.0
CSH1_k127_6058_8 MAPEG family - - - 0.00000000000000000000000000000000000000548 152.0
CSH1_k127_6058_9 Biopolymer transport protein K03559 - - 0.000000000000000000000000000000000004018 143.0
CSH1_k127_744983_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1154.0
CSH1_k127_744983_1 AMP-binding enzyme - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 2.958e-200 638.0
CSH1_k127_744983_10 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000006299 251.0
CSH1_k127_744983_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 592.0
CSH1_k127_744983_3 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 429.0
CSH1_k127_744983_4 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 433.0
CSH1_k127_744983_5 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 359.0
CSH1_k127_744983_6 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 305.0
CSH1_k127_744983_7 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 318.0
CSH1_k127_744983_8 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005826 253.0
CSH1_k127_744983_9 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007709 250.0
CSH1_k127_751913_0 modulator of DNA gyrase K03568 - - 1.979e-210 672.0
CSH1_k127_751913_1 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 621.0
CSH1_k127_751913_10 maF-like protein K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.00000000000000000000000000000000000000000000000000000001096 203.0
CSH1_k127_751913_11 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000000001205 160.0
CSH1_k127_751913_12 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.000000000000000000000000000000000000000001208 162.0
CSH1_k127_751913_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000001272 146.0
CSH1_k127_751913_14 Protein of unknown function (DUF615) K09889 - - 0.000000000000000000000001094 110.0
CSH1_k127_751913_2 Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 486.0
CSH1_k127_751913_3 5-(carboxyamino)imidazole ribonucleotide synthase activity K01589 GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 412.0
CSH1_k127_751913_4 Protein of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 372.0
CSH1_k127_751913_5 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 338.0
CSH1_k127_751913_6 Type II secretory pathway component ExeA K02450,K12283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 322.0
CSH1_k127_751913_7 DNA polymerase III, delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000004911 244.0
CSH1_k127_751913_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000009682 234.0
CSH1_k127_751913_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000009787 225.0
CSH1_k127_810998_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 1.731e-198 643.0
CSH1_k127_810998_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 360.0
CSH1_k127_810998_2 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000176 148.0
CSH1_k127_822519_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 436.0
CSH1_k127_822519_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 430.0
CSH1_k127_822519_2 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 409.0
CSH1_k127_822519_3 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 373.0
CSH1_k127_822519_4 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000425 280.0
CSH1_k127_822519_5 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000002322 231.0
CSH1_k127_822519_6 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000005864 155.0
CSH1_k127_822519_7 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000001722 132.0
CSH1_k127_822519_8 - - - - 0.000000000000007257 78.0
CSH1_k127_831932_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.794e-236 750.0
CSH1_k127_831932_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003147 241.0
CSH1_k127_831932_2 - - - - 0.0000000000000000000000000000000008868 134.0
CSH1_k127_831932_3 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000000000578 125.0
CSH1_k127_889791_0 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.0 1109.0
CSH1_k127_889791_1 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 511.0
CSH1_k127_889791_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 495.0
CSH1_k127_889791_3 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 400.0
CSH1_k127_889791_4 TraB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 302.0
CSH1_k127_889791_5 CHAT domain - - - 0.000000000000000000000000000000000002178 157.0
CSH1_k127_889791_6 Planctomycete cytochrome C - - - 0.000000000000000000000000000000006928 135.0
CSH1_k127_889791_7 6-phosphogluconolactonase activity - - - 0.0000000000000000000001225 106.0
CSH1_k127_889791_8 - - - - 0.000000000000001183 81.0
CSH1_k127_891762_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 402.0
CSH1_k127_891762_1 Oxidoreductase FAD-binding domain K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 376.0
CSH1_k127_891762_10 - - - - 0.0000000001491 69.0
CSH1_k127_891762_2 chemotaxis protein K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 360.0
CSH1_k127_891762_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 324.0
CSH1_k127_891762_4 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000005998 233.0
CSH1_k127_891762_5 response regulator K02657 - - 0.0000000000000000000000000000000000000000000000000000000000006544 213.0
CSH1_k127_891762_6 cheY-homologous receiver domain K02658 - - 0.00000000000000000000000000000000000000002488 156.0
CSH1_k127_891762_7 Two component signalling adaptor domain K02659 - - 0.0000000000000000000000000000000004216 138.0
CSH1_k127_891762_8 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.0000000000000000000000000000000009197 147.0
CSH1_k127_891762_9 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000002431 123.0
CSH1_k127_898628_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1346.0
CSH1_k127_898628_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 590.0
CSH1_k127_898628_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 398.0
CSH1_k127_898628_3 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 386.0
CSH1_k127_898628_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002452 276.0
CSH1_k127_898628_5 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002825 269.0
CSH1_k127_898628_6 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000324 231.0
CSH1_k127_898628_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000003111 218.0
CSH1_k127_898628_8 Regulatory protein, FmdB family - - - 0.000000000000000000000006867 106.0
CSH1_k127_911038_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 452.0
CSH1_k127_911038_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 327.0
CSH1_k127_911038_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 325.0
CSH1_k127_911038_3 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000004274 236.0
CSH1_k127_911038_4 Biopolymer transport protein K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000001709 156.0
CSH1_k127_911038_5 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000003776 153.0
CSH1_k127_911038_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000007738 123.0
CSH1_k127_911038_7 Membrane protein TolA K03646 - - 0.00000000007886 72.0
CSH1_k127_93378_0 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 9.831e-256 799.0
CSH1_k127_93378_1 CHASE2 domain protein - - - 2.831e-237 749.0
CSH1_k127_93378_10 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009218 261.0
CSH1_k127_93378_11 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001339 237.0
CSH1_k127_93378_12 Acetyl-coenzyme A transporter 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003084 246.0
CSH1_k127_93378_13 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000003827 209.0
CSH1_k127_93378_14 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000003157 205.0
CSH1_k127_93378_15 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000001643 192.0
CSH1_k127_93378_16 - - - - 0.000000000000000000000000000000000000000004279 158.0
CSH1_k127_93378_17 - - - - 0.000000000000000000000000000003891 139.0
CSH1_k127_93378_18 oxygen carrier activity K07216 - - 0.000000000000000000000000469 113.0
CSH1_k127_93378_2 Carboxypeptidase - - - 3.035e-212 674.0
CSH1_k127_93378_20 - - - - 0.0000000000000006051 79.0
CSH1_k127_93378_21 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.000000002495 68.0
CSH1_k127_93378_3 Major Facilitator Superfamily K03301 - - 1.602e-203 641.0
CSH1_k127_93378_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 610.0
CSH1_k127_93378_5 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 557.0
CSH1_k127_93378_6 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 531.0
CSH1_k127_93378_7 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 482.0
CSH1_k127_93378_8 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 410.0
CSH1_k127_93378_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000001295 287.0
CSH1_k127_971230_0 FAD linked oxidase domain protein - - - 0.0 1874.0
CSH1_k127_971230_1 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000001215 220.0
CSH1_k127_985041_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.597e-301 949.0
CSH1_k127_985041_1 Succinyldiaminopimelate K14261,K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 502.0
CSH1_k127_985041_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 406.0
CSH1_k127_985041_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000004233 134.0
CSH1_k127_985041_4 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000000000000000000000000000000001012 137.0