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Overview

ID MAG00600
Name CSH1_bin.7
Sample SMP0013
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order Methanomassiliicoccales
Family UBA472
Genus JAJRAN01
Species
Assembly information
Completeness (%) 60.35
Contamination (%) 0.65
GC content (%) 57.0
N50 (bp) 3,598
Genome size (bp) 1,138,652

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1245

Gene name Description KEGG GOs EC E-value Score Sequence
CSH1_k127_1033985_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 470.0
CSH1_k127_1033985_1 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004403 260.0
CSH1_k127_1038228_0 Uroporphyrinogen decarboxylase K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 399.0
CSH1_k127_1038228_1 Hydantoinase/oxoprolinase N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000009369 241.0
CSH1_k127_1038228_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000001798 151.0
CSH1_k127_1038228_3 - - - - 0.0000000000000000000000000001437 117.0
CSH1_k127_1039291_0 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 374.0
CSH1_k127_1039291_1 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000004214 247.0
CSH1_k127_1046662_0 HMGL-like K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 488.0
CSH1_k127_1046662_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 354.0
CSH1_k127_1046662_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000001004 118.0
CSH1_k127_1046662_3 - - - - 0.000000000000000000000003278 104.0
CSH1_k127_1046662_4 amino acid-binding ACT domain protein - - - 0.0000000000000002752 85.0
CSH1_k127_1048548_0 Pyruvate phosphate dikinase, PEP pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 331.0
CSH1_k127_1050121_0 cyclohydrolase - - - 0.00000000000000000000005259 103.0
CSH1_k127_1050121_1 - - - - 0.0000000000000000000001246 106.0
CSH1_k127_1050121_2 FMN binding - - - 0.00000000000001023 79.0
CSH1_k127_1050121_3 Transcriptional regulator - - - 0.0000000000001712 70.0
CSH1_k127_1104909_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974,K18105 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4,6.5.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000005942 252.0
CSH1_k127_1104909_1 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000007975 220.0
CSH1_k127_1104909_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000006374 215.0
CSH1_k127_1104909_3 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000009904 158.0
CSH1_k127_1104909_4 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.00000000000000000000000009126 108.0
CSH1_k127_1107534_0 Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 508.0
CSH1_k127_1107534_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 450.0
CSH1_k127_1107534_2 NADH ubiquinone oxidoreductase subunit 1 (Chain H) K00337,K22163 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 326.0
CSH1_k127_1107534_3 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002203 231.0
CSH1_k127_1107534_4 NADH ubiquinone oxidoreductase 27 kD subunit K00332,K22160 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000003714 148.0
CSH1_k127_1107534_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000008888 116.0
CSH1_k127_1107534_6 NADH ubiquinone oxidoreductase subunit 11 or 4L (chain K) K00340,K05576,K22166 - 1.5.98.3,1.6.5.3 0.000000000000000000000000003927 115.0
CSH1_k127_1107534_7 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000001301 83.0
CSH1_k127_1107534_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339,K05578 - 1.6.5.3 0.00000000003037 68.0
CSH1_k127_1107534_9 - - - - 0.00002568 49.0
CSH1_k127_1173639_0 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 9.196e-257 803.0
CSH1_k127_1173639_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 428.0
CSH1_k127_1173639_2 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007211 260.0
CSH1_k127_1173639_3 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000008037 164.0
CSH1_k127_1174536_0 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 319.0
CSH1_k127_1174536_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008109 261.0
CSH1_k127_1174536_2 - - - - 0.00000000000000000000000000000000000001329 152.0
CSH1_k127_1174536_3 - - - - 0.0000000000000000000000001152 111.0
CSH1_k127_1174536_4 PFAM elongation factor Tu domain 2 - - - 0.00003134 48.0
CSH1_k127_1181328_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 309.0
CSH1_k127_1181328_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000007022 213.0
CSH1_k127_1181328_2 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000004391 117.0
CSH1_k127_1181328_3 DNA polymerase X family K02347 - - 0.00000005286 63.0
CSH1_k127_1196665_0 PFAM NmrA family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 288.0
CSH1_k127_1196665_1 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000002975 229.0
CSH1_k127_1196665_2 3-Demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000002035 218.0
CSH1_k127_1196665_3 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000009876 186.0
CSH1_k127_1196665_4 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000002458 149.0
CSH1_k127_1196665_5 SPTR D1C1B9 DinB family protein - - - 0.000000000000000000001021 101.0
CSH1_k127_120026_0 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 430.0
CSH1_k127_120026_1 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000009584 108.0
CSH1_k127_120026_2 Belongs to the UPF0218 family K09735 - - 0.00000000000000000004955 95.0
CSH1_k127_120026_3 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000005648 79.0
CSH1_k127_120026_4 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000005186 74.0
CSH1_k127_1230083_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 443.0
CSH1_k127_1230083_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000007533 184.0
CSH1_k127_1230083_2 COG1403 Restriction endonuclease - - - 0.0000007572 60.0
CSH1_k127_1230083_3 hydrolase K01560,K07025 - 3.8.1.2 0.0002626 45.0
CSH1_k127_1240829_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000004661 240.0
CSH1_k127_1240829_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000001259 181.0
CSH1_k127_1240829_2 coproporphyrinogen III oxidase - - - 0.000000000000000000000000005814 118.0
CSH1_k127_125053_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 511.0
CSH1_k127_125053_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 363.0
CSH1_k127_1266626_0 ABC transporter K00400,K16786,K16787 - - 9.09e-197 623.0
CSH1_k127_1268740_0 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000007589 147.0
CSH1_k127_1268740_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000001078 135.0
CSH1_k127_1268740_2 - - - - 0.0000001463 59.0
CSH1_k127_1278418_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 430.0
CSH1_k127_1278418_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000000000000000001396 168.0
CSH1_k127_1311913_0 Beta-Casp domain K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 403.0
CSH1_k127_1311913_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000003679 144.0
CSH1_k127_1320354_0 Rhodanese-like domain K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 509.0
CSH1_k127_1320354_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000001405 104.0
CSH1_k127_1320354_2 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000001335 64.0
CSH1_k127_1328098_0 DegT/DnrJ/EryC1/StrS aminotransferase family K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 456.0
CSH1_k127_1328098_1 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 304.0
CSH1_k127_1328098_2 - - - - 0.0000001731 63.0
CSH1_k127_1328098_3 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0001268 44.0
CSH1_k127_1382412_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 1.864e-213 681.0
CSH1_k127_1382412_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 498.0
CSH1_k127_1382412_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000003126 99.0
CSH1_k127_1386831_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 320.0
CSH1_k127_1386831_1 and related - - - 0.0000000000000000000000000000000000000000000000000000000006534 213.0
CSH1_k127_1386831_2 COG0110 Acetyltransferase (isoleucine patch superfamily) - - - 0.0000000000000000000000000000000000000000002051 163.0
CSH1_k127_1386831_3 Glycosyl transferase 4-like domain - - - 0.000000000000003926 77.0
CSH1_k127_1420654_0 phenylalanine-tRNA ligase activity K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 541.0
CSH1_k127_1420654_1 Belongs to the HMG-CoA reductase family K00021,K00054 GO:0003674,GO:0003824,GO:0004420,GO:0006629,GO:0006694,GO:0006720,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016125,GO:0016126,GO:0016491,GO:0016614,GO:0016616,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 1.1.1.34,1.1.1.88 0.00000000000000000000000000001094 119.0
CSH1_k127_1427962_0 Rieske 2Fe-2S - - - 0.000000000000000000000000000000023 130.0
CSH1_k127_1427962_1 Transcriptional regulator K03718 - - 0.0003491 52.0
CSH1_k127_1437299_0 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006729 263.0
CSH1_k127_1437299_1 PFAM response regulator receiver K03406 - - 0.00000000000000000000000000000000000000000000000000000005164 222.0
CSH1_k127_1437299_2 histidine kinase A domain protein domain protein - - - 0.0000000000000000000000000000000001431 153.0
CSH1_k127_1437299_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000008279 120.0
CSH1_k127_1463210_0 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 342.0
CSH1_k127_1463210_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 286.0
CSH1_k127_1463210_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025,K08723 - 3.1.3.5 0.000000000000000004566 92.0
CSH1_k127_1463210_3 Protein of unknown function DUF131 - - - 0.00000003584 60.0
CSH1_k127_1464839_0 Histidine kinase K02486 - 2.7.13.3 0.000000000000003515 89.0
CSH1_k127_1464839_1 Major Facilitator Superfamily - - - 0.0000000000001108 77.0
CSH1_k127_1464839_2 TIGRFAM Diguanylate cyclase - - - 0.0000000000005284 82.0
CSH1_k127_146583_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 531.0
CSH1_k127_146583_1 - - - - 0.0000000000000000004765 93.0
CSH1_k127_146583_2 but it may be involved in stabilization of the trimeric complex - - - 0.0000000000008059 70.0
CSH1_k127_146583_3 Sodium/hydrogen exchanger family - - - 0.00000002141 57.0
CSH1_k127_1472020_0 Belongs to the UPF0284 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 309.0
CSH1_k127_1472020_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.00000000000000000000000000000000000000001941 165.0
CSH1_k127_1472020_2 Cytidylyltransferase K19712 - 2.7.7.62 0.00000000000000000000000000000001506 135.0
CSH1_k127_1472020_3 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000001875 78.0
CSH1_k127_1504383_0 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000009788 198.0
CSH1_k127_1504383_1 xylanase chitin deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000001644 166.0
CSH1_k127_1504383_2 Domain of unknown function (DUF3786) - - - 0.000000000000000000000003463 108.0
CSH1_k127_1547790_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 302.0
CSH1_k127_1547790_1 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000004624 237.0
CSH1_k127_155682_0 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000111 204.0
CSH1_k127_155682_1 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00007518 53.0
CSH1_k127_156015_0 PFAM Methyl-coenzyme M reductase K03421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 329.0
CSH1_k127_156015_1 Belongs to the UPF0288 family - - - 0.00000000000000000000000000000000000000000000009272 177.0
CSH1_k127_156015_2 - - - - 0.000000000295 69.0
CSH1_k127_1560357_0 Isocitrate/isopropylmalate dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 586.0
CSH1_k127_1560357_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000001049 262.0
CSH1_k127_1560357_2 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000001113 244.0
CSH1_k127_1596882_0 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 347.0
CSH1_k127_1596882_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000003236 184.0
CSH1_k127_1596882_2 TIGRFAM geranylgeranyl reductase family - - - 0.00000000000000000000000000001714 126.0
CSH1_k127_1607470_0 PFAM peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002565 277.0
CSH1_k127_1609582_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000624 503.0
CSH1_k127_1609582_1 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000001451 172.0
CSH1_k127_1609582_10 Mitomycin resistance protein K07343 - - 0.0000003559 55.0
CSH1_k127_1609582_12 AAA ATPase domain - - - 0.0001018 47.0
CSH1_k127_1609582_2 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000001047 136.0
CSH1_k127_1609582_3 Predicted membrane protein (DUF2085) - - - 0.00000000000000000751 92.0
CSH1_k127_1609582_4 cell redox homeostasis - - - 0.00000000000000001497 85.0
CSH1_k127_1609582_5 COG0095 Lipoate-protein ligase A K03800 GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0051604,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901681 6.3.1.20 0.00000000000005213 74.0
CSH1_k127_1609582_6 Protein of unknown function (DUF1295) - - - 0.00000000001235 73.0
CSH1_k127_1609582_7 - - - - 0.00000000002171 68.0
CSH1_k127_1609582_8 ferredoxin-thioredoxin reductase activity - - - 0.00000000006247 71.0
CSH1_k127_1609582_9 Flavin reductase like domain - - - 0.0000000003866 68.0
CSH1_k127_1616652_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 336.0
CSH1_k127_1616652_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000001304 246.0
CSH1_k127_1616652_2 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000002594 233.0
CSH1_k127_1616652_3 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000131 225.0
CSH1_k127_1616652_4 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000005957 97.0
CSH1_k127_1616652_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000003677 55.0
CSH1_k127_1624575_0 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 377.0
CSH1_k127_1624575_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 377.0
CSH1_k127_1624575_10 Domain of unknown function (DUF749) - - - 0.0000002252 56.0
CSH1_k127_1624575_2 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000009093 250.0
CSH1_k127_1624575_3 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000000002017 222.0
CSH1_k127_1624575_4 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000007281 186.0
CSH1_k127_1624575_5 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000003594 187.0
CSH1_k127_1624575_6 signal transduction protein with CBS domains - - - 0.000000000000000000000000000000201 131.0
CSH1_k127_1624575_7 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000004116 127.0
CSH1_k127_1624575_8 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000004383 117.0
CSH1_k127_1624575_9 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000005157 115.0
CSH1_k127_1627431_0 Belongs to the CarB family K01955 - 6.3.5.5 1.759e-240 763.0
CSH1_k127_1627431_1 spore germination - - - 0.00000000000007322 76.0
CSH1_k127_1627431_2 helix_turn_helix ASNC type K03719 - - 0.000005264 58.0
CSH1_k127_1627431_3 helix_turn_helix ASNC type K03719 - - 0.00003845 55.0
CSH1_k127_1644836_0 methanogenesis marker protein 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 386.0
CSH1_k127_1644836_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 366.0
CSH1_k127_1644836_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000007345 229.0
CSH1_k127_1644836_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000001325 103.0
CSH1_k127_1648143_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 348.0
CSH1_k127_1648143_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 284.0
CSH1_k127_1648143_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000003003 219.0
CSH1_k127_1648143_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000002728 145.0
CSH1_k127_167005_0 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000156 170.0
CSH1_k127_1689793_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 353.0
CSH1_k127_1689793_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000007157 264.0
CSH1_k127_1689793_2 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000005576 85.0
CSH1_k127_1714103_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 325.0
CSH1_k127_1714103_1 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 240.0
CSH1_k127_1714103_2 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000002951 200.0
CSH1_k127_1714103_3 toxin-antitoxin pair type II binding - - - 0.000000000000000000008191 94.0
CSH1_k127_1714103_4 COG1522 Transcriptional regulators - - - 0.0004205 51.0
CSH1_k127_1716084_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 579.0
CSH1_k127_1716084_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 563.0
CSH1_k127_1716084_2 Pfam:DUF137 K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000936 264.0
CSH1_k127_1716084_3 pfkB family carbohydrate kinase K22026 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006213,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008617,GO:0008906,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009129,GO:0009130,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042278,GO:0042455,GO:0043167,GO:0043168,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046033,GO:0046035,GO:0046085,GO:0046087,GO:0046102,GO:0046128,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1905108 2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000009003 254.0
CSH1_k127_1716084_4 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000001069 130.0
CSH1_k127_1716084_5 - - - - 0.000000000000000007118 87.0
CSH1_k127_1716084_6 Double zinc ribbon - - - 0.00000007776 64.0
CSH1_k127_1716084_7 RNA-binding protein involved in rRNA processing K07569 - - 0.000000989 55.0
CSH1_k127_1722151_0 DEAD/H associated K03724 - - 2.611e-290 911.0
CSH1_k127_1745517_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001515 246.0
CSH1_k127_1745517_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000007719 142.0
CSH1_k127_1793874_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 557.0
CSH1_k127_1793874_1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 289.0
CSH1_k127_1793874_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000003872 233.0
CSH1_k127_1793874_3 Pfam 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000002813 54.0
CSH1_k127_1804784_0 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000001582 213.0
CSH1_k127_1804784_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000001674 205.0
CSH1_k127_1804784_2 Transcriptional regulator K07722 - - 0.0000000000000000000000002839 111.0
CSH1_k127_1826489_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 346.0
CSH1_k127_1826489_1 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000007999 76.0
CSH1_k127_1844188_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 420.0
CSH1_k127_1844188_1 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 314.0
CSH1_k127_1844188_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000002914 194.0
CSH1_k127_1844188_3 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000000016 103.0
CSH1_k127_1844188_4 - - - - 0.000000002269 63.0
CSH1_k127_1858710_0 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002289 248.0
CSH1_k127_1858710_1 NUDIX domain K08310 - 3.6.1.67 0.00000000000000002792 87.0
CSH1_k127_1858710_2 Protein of unknown function (DUF1059) - - - 0.000000001106 62.0
CSH1_k127_1870000_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000007226 117.0
CSH1_k127_1870000_1 Thioredoxin-like domain K03671 - - 0.00000000000000003534 87.0
CSH1_k127_1894331_0 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000005626 194.0
CSH1_k127_1895467_0 Metallopeptidase family M24 K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 299.0
CSH1_k127_1895467_1 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003636 286.0
CSH1_k127_1895467_2 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000003359 271.0
CSH1_k127_1895467_3 Formyl transferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000002693 195.0
CSH1_k127_1895467_4 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000000000000000006534 132.0
CSH1_k127_1895467_5 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000003599 134.0
CSH1_k127_1899538_0 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000247 147.0
CSH1_k127_1899538_1 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000001111 139.0
CSH1_k127_1899538_2 transcription regulator activity - - - 0.000000000000001175 85.0
CSH1_k127_1941446_0 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 599.0
CSH1_k127_1941446_1 K -dependent Na Ca exchanger K07301 - - 0.0000000000000000000000000000000000000000000008851 175.0
CSH1_k127_1941446_2 - - - - 0.000000000000000000001623 102.0
CSH1_k127_1941446_3 Papain family cysteine protease - - - 0.0000000002695 72.0
CSH1_k127_1945627_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 4.979e-205 655.0
CSH1_k127_1945627_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 541.0
CSH1_k127_1945627_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.4.1.2,1.4.1.3,1.4.1.4 0.000000000000000000000000000002117 122.0
CSH1_k127_1951028_0 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000003614 220.0
CSH1_k127_1951028_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000001287 59.0
CSH1_k127_196348_0 TIGRFAM arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000001778 214.0
CSH1_k127_196348_1 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000002101 191.0
CSH1_k127_1970628_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 9.921e-206 651.0
CSH1_k127_1970628_1 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 461.0
CSH1_k127_1970628_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000001093 128.0
CSH1_k127_1970628_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000002366 53.0
CSH1_k127_1972095_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000001384 226.0
CSH1_k127_1972095_1 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000004409 211.0
CSH1_k127_1972095_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000001076 131.0
CSH1_k127_1975507_0 Belongs to the peptidase S16 family - - - 2.465e-260 824.0
CSH1_k127_1975507_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006763 257.0
CSH1_k127_199957_0 ATPase activity K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006899 276.0
CSH1_k127_199957_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000004404 198.0
CSH1_k127_199957_2 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000003419 61.0
CSH1_k127_2005625_0 SMART Peptidase A22, presenilin signal peptide - - - 0.00000000000000000000000000000000000000000000000000000004481 209.0
CSH1_k127_2005625_1 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.00000000000002011 75.0
CSH1_k127_2005625_2 - - - - 0.000006179 55.0
CSH1_k127_2005625_3 Major Facilitator Superfamily - - - 0.0001459 51.0
CSH1_k127_2013611_0 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000001068 193.0
CSH1_k127_2013611_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.00000000000000000000002529 100.0
CSH1_k127_2017333_0 Methanogenesis marker 16 metalloprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 384.0
CSH1_k127_2017333_1 Hydantoinase/oxoprolinase N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 339.0
CSH1_k127_2034526_0 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 400.0
CSH1_k127_2034526_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000009984 233.0
CSH1_k127_2034526_2 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000176 44.0
CSH1_k127_2041054_0 Radical SAM domain protein K09711 - - 0.0000000000000000000000000000000000000000002083 170.0
CSH1_k127_2041054_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000004166 144.0
CSH1_k127_2041054_2 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000004304 88.0
CSH1_k127_2050309_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 361.0
CSH1_k127_2050309_1 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000006064 249.0
CSH1_k127_2050309_2 cysteine-tRNA ligase activity K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000008845 208.0
CSH1_k127_2050309_3 Peptidase, M28 family - - - 0.00000000002355 75.0
CSH1_k127_2050330_0 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 342.0
CSH1_k127_2050330_1 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 323.0
CSH1_k127_2054739_0 plastoquinone (Complex I) K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 477.0
CSH1_k127_2054739_1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001969 252.0
CSH1_k127_2077059_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 470.0
CSH1_k127_2077059_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 464.0
CSH1_k127_2077059_2 TatD related DNase K07049 - - 0.000000000000000000000000000000000000007931 147.0
CSH1_k127_2077059_3 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000000001844 87.0
CSH1_k127_2077059_4 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000004608 87.0
CSH1_k127_21271_0 PFAM ribosomal protein S8E K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000001519 162.0
CSH1_k127_21271_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000004087 131.0
CSH1_k127_21271_2 Uncharacterized ArCR, COG1888 K09732 - - 0.0000000000000000000000000000007137 128.0
CSH1_k127_21271_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.00000000000000000006869 92.0
CSH1_k127_2167_0 Pyridine nucleotide-disulphide oxidoreductase - - - 3.76e-234 747.0
CSH1_k127_2167_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 359.0
CSH1_k127_2167_2 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000001307 248.0
CSH1_k127_2167_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000001663 211.0
CSH1_k127_2175599_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 554.0
CSH1_k127_2211420_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.6e-316 982.0
CSH1_k127_2211420_1 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 338.0
CSH1_k127_2211420_2 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000001732 164.0
CSH1_k127_2211420_3 - - - - 0.00000000000000000000003254 103.0
CSH1_k127_2211420_4 - - - - 0.0000000000000000004149 89.0
CSH1_k127_2213611_0 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 326.0
CSH1_k127_2213611_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 296.0
CSH1_k127_2213611_2 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000001283 214.0
CSH1_k127_2213611_3 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000775 125.0
CSH1_k127_2213611_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000001182 122.0
CSH1_k127_2213611_5 NMD3 family K07562 - - 0.0000000000007562 72.0
CSH1_k127_2213611_6 oxidoreductase activity - - - 0.0000192 56.0
CSH1_k127_2213752_0 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 572.0
CSH1_k127_2213752_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 544.0
CSH1_k127_2213752_10 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000003546 149.0
CSH1_k127_2213752_11 - - - - 0.0000000000000000000000000000002564 128.0
CSH1_k127_2213752_12 Ribbon-helix-helix protein, copG family K07722 - - 0.0000000000000000000009303 98.0
CSH1_k127_2213752_13 Domain of unknown function (DUF1610) K07580 - - 0.00000000000000000004628 90.0
CSH1_k127_2213752_14 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00004901 49.0
CSH1_k127_2213752_2 of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 330.0
CSH1_k127_2213752_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 320.0
CSH1_k127_2213752_4 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003686 276.0
CSH1_k127_2213752_5 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001336 272.0
CSH1_k127_2213752_6 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 259.0
CSH1_k127_2213752_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000006399 216.0
CSH1_k127_2213752_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000006965 198.0
CSH1_k127_2213752_9 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000004778 174.0
CSH1_k127_222716_0 PFAM NADH-ubiquinone oxidoreductase chain 49kDa K00333,K14090 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 358.0
CSH1_k127_222716_1 PFAM respiratory-chain NADH dehydrogenase subunit 1 K14087 - - 0.0000000000000000000000000000000000000000000000000000000001743 214.0
CSH1_k127_222716_2 PFAM NADH ubiquinone oxidoreductase, 20 K00331,K14088 - 1.6.5.3 0.000000000000000000000000000000000000000000000000003581 188.0
CSH1_k127_222716_3 NADH Ubiquinone plastoquinone (Complex I) K05565,K14086 - - 0.000000000000000000000000000006685 128.0
CSH1_k127_222716_4 4Fe-4S dicluster domain K14091 - - 0.000000000000000000000002342 106.0
CSH1_k127_222716_5 NADH dehydrogenase (Ubiquinone), 30 kDa subunit K00332,K14089 - 1.6.5.3 0.00002025 51.0
CSH1_k127_2228269_0 prephenate dehydrogenase K04517,K14170,K14187 - 1.3.1.12,4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000721 238.0
CSH1_k127_2228269_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000001078 226.0
CSH1_k127_2228269_2 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.0000000000004905 70.0
CSH1_k127_2236286_0 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007487 275.0
CSH1_k127_2236286_1 Domain of unknown function (DUF296) - - - 0.0000000000000000000000000000000000000000000000004285 182.0
CSH1_k127_2255500_0 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 409.0
CSH1_k127_2255500_1 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000004041 190.0
CSH1_k127_2255500_2 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000001647 151.0
CSH1_k127_2255500_3 DsrE/DsrF-like family K07235 - - 0.000000000000000000000000000000000004239 140.0
CSH1_k127_2255500_4 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000001094 110.0
CSH1_k127_2255500_5 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000004936 102.0
CSH1_k127_2255500_6 4Fe-4S dicluster domain - - - 0.00000000000000000002686 94.0
CSH1_k127_2255500_7 DsrH like protein K07237 - - 0.0000000001089 66.0
CSH1_k127_2269994_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 484.0
CSH1_k127_2269994_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 360.0
CSH1_k127_2269994_2 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000000000000000000000000000001011 231.0
CSH1_k127_2269994_3 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000000000000000000000000000001444 150.0
CSH1_k127_2269994_4 COG1042 Acyl-CoA synthetase (NDP forming) K01905,K22224 - 6.2.1.13 0.000000000000000000000001328 106.0
CSH1_k127_2273451_0 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000004753 192.0
CSH1_k127_2273451_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000001069 53.0
CSH1_k127_2273451_2 FR47-like protein K03789 - 2.3.1.128 0.000007756 59.0
CSH1_k127_2278622_0 C-terminal region of MMR_HSR1 domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 421.0
CSH1_k127_2278622_1 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 306.0
CSH1_k127_2278622_2 SPFH domain-Band 7 family - - - 0.0000101 57.0
CSH1_k127_2295922_0 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000002624 209.0
CSH1_k127_2295922_1 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.00000000000000000000000000000000000000000000000007842 180.0
CSH1_k127_2295922_2 DnaB-like helicase C terminal domain - - - 0.00000000000000000000000000000000000000545 155.0
CSH1_k127_2295922_3 DnaB-like helicase C terminal domain - - - 0.0000000000000000000000000000000000007728 149.0
CSH1_k127_2299263_0 DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000001293 211.0
CSH1_k127_2299263_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000001444 187.0
CSH1_k127_2299263_2 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000006251 127.0
CSH1_k127_2300533_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.000000000000000000000000000000000000001559 152.0
CSH1_k127_2300533_1 Protein of unknown function (DUF3198) - - - 0.0005206 47.0
CSH1_k127_2313803_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 595.0
CSH1_k127_2313803_1 PP-loop family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000468 246.0
CSH1_k127_2313803_2 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000001265 124.0
CSH1_k127_2327770_0 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000001481 112.0
CSH1_k127_2327770_1 PKD domain - - - 0.0000001763 65.0
CSH1_k127_2367368_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.4.2.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 459.0
CSH1_k127_2367368_1 - - - - 0.00000000000000001111 88.0
CSH1_k127_2372436_0 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000005954 177.0
CSH1_k127_2372436_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000006493 151.0
CSH1_k127_2372436_2 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.0000000000000000000000000000000003743 136.0
CSH1_k127_2372436_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000001182 109.0
CSH1_k127_2372436_4 AAA domain - - - 0.00005441 46.0
CSH1_k127_2377780_0 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000003734 218.0
CSH1_k127_2377780_1 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000009981 176.0
CSH1_k127_2377780_2 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.0000000000000000000000000000000000000675 149.0
CSH1_k127_2377780_3 PFAM Xylose isomerase domain protein TIM barrel K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000003689 116.0
CSH1_k127_2381957_0 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003406 283.0
CSH1_k127_2381957_1 - - - - 0.00000000000000000000002845 102.0
CSH1_k127_2381957_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000005947 74.0
CSH1_k127_2382611_0 PFAM Methionine synthase, B12-binding module, cap domain protein - - - 0.00000000000000000000000000000000000001148 147.0
CSH1_k127_2382611_1 Uroporphyrinogen decarboxylase K01599 - 4.1.1.37 0.00000000000001494 75.0
CSH1_k127_2382611_2 Methionine synthase B12-binding module cap domain protein K16179 - - 0.0000000000000166 78.0
CSH1_k127_2382611_3 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000001284 71.0
CSH1_k127_2382910_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 388.0
CSH1_k127_2382910_1 Family membership - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 311.0
CSH1_k127_2393224_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 542.0
CSH1_k127_2409292_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 316.0
CSH1_k127_2409292_1 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001655 288.0
CSH1_k127_2409292_2 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001204 248.0
CSH1_k127_2409292_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000533 54.0
CSH1_k127_2409292_4 Protein of unknown function (DUF2797) - - - 0.0002545 51.0
CSH1_k127_2438679_0 Domain of unknown function (DUF4443) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006742 245.0
CSH1_k127_2438679_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000525 70.0
CSH1_k127_2438679_2 - - - - 0.00000000004565 68.0
CSH1_k127_2458046_0 DEAD/H associated K03724 - - 9.676e-214 681.0
CSH1_k127_2465613_0 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 449.0
CSH1_k127_2465613_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 447.0
CSH1_k127_2465613_2 PFAM NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000004064 140.0
CSH1_k127_2500201_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 319.0
CSH1_k127_2500201_1 Sodium hydrogen exchanger K03455 - - 0.0000000007488 69.0
CSH1_k127_2502219_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005304 297.0
CSH1_k127_2502219_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000001728 190.0
CSH1_k127_2506772_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1022.0
CSH1_k127_2506772_1 Helix-turn-helix XRE-family like proteins K07728 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 334.0
CSH1_k127_2506772_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000001788 132.0
CSH1_k127_2506772_3 - - - - 0.000000000000000000000000000001463 129.0
CSH1_k127_2506772_4 helix_turn_helix, Arsenical Resistance Operon Repressor K07721 - - 0.000000000000000000000001018 111.0
CSH1_k127_2506772_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000001479 98.0
CSH1_k127_2531369_0 Archaeal transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000000000000885 222.0
CSH1_k127_2531369_1 Lamin Tail Domain - - - 0.000000003626 69.0
CSH1_k127_2552570_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007828 371.0
CSH1_k127_2552570_1 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 287.0
CSH1_k127_2552570_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000002607 118.0
CSH1_k127_2558095_0 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 522.0
CSH1_k127_2558095_1 Hydroxymethylglutaryl-coenzyme A reductase K00021,K00054 - 1.1.1.34,1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 320.0
CSH1_k127_2561450_0 phosphoribosylformylglycinamidine cyclo-ligase activity K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 397.0
CSH1_k127_2561450_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000006764 190.0
CSH1_k127_2561450_2 Protein of unknown function (DUF2769) - - - 0.0000003344 55.0
CSH1_k127_2600788_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 430.0
CSH1_k127_2600788_1 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 308.0
CSH1_k127_2600788_2 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 293.0
CSH1_k127_2600788_3 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.0000000000000000000000000000000000003478 150.0
CSH1_k127_2600788_4 thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000009886 144.0
CSH1_k127_2600788_5 Dual specificity protein phosphatase 8 K04459,K20216 GO:0000187,GO:0000188,GO:0001558,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002831,GO:0002832,GO:0002833,GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006986,GO:0007275,GO:0007399,GO:0007568,GO:0008138,GO:0008150,GO:0008152,GO:0008340,GO:0008361,GO:0008579,GO:0009791,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010259,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010646,GO:0010647,GO:0010648,GO:0010721,GO:0010769,GO:0010771,GO:0010975,GO:0010977,GO:0016043,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017017,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023056,GO:0023057,GO:0030154,GO:0030308,GO:0030516,GO:0030517,GO:0031323,GO:0031324,GO:0031325,GO:0031344,GO:0031345,GO:0031347,GO:0031348,GO:0031349,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032102,GO:0032103,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032535,GO:0032872,GO:0032873,GO:0032879,GO:0032880,GO:0033549,GO:0033673,GO:0033674,GO:0035966,GO:0036211,GO:0040008,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0043085,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043405,GO:0043406,GO:0043407,GO:0043408,GO:0043409,GO:0043410,GO:0043412,GO:0043549,GO:0043900,GO:0043901,GO:0043902,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045859,GO:0045860,GO:0045926,GO:0045936,GO:0045937,GO:0046328,GO:0046329,GO:0046686,GO:0046688,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048638,GO:0048640,GO:0048679,GO:0048681,GO:0048686,GO:0048688,GO:0048690,GO:0048692,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050770,GO:0050771,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051019,GO:0051093,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051338,GO:0051347,GO:0051348,GO:0051960,GO:0051961,GO:0060255,GO:0060284,GO:0060341,GO:0061387,GO:0065007,GO:0065008,GO:0065009,GO:0070302,GO:0070303,GO:0070570,GO:0070571,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071902,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:0120035,GO:0140096,GO:1900180,GO:1900181,GO:1900182,GO:1900424,GO:1900425,GO:1900426,GO:1901564,GO:1902531,GO:1902532,GO:1902533,GO:1903034,GO:1903035,GO:1903827,GO:1903828,GO:1903829,GO:1903853,GO:1903854,GO:2000026 3.1.3.16,3.1.3.48 0.0001484 47.0
CSH1_k127_2618186_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 5.317e-199 636.0
CSH1_k127_2618186_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 423.0
CSH1_k127_2618186_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 342.0
CSH1_k127_2618186_3 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 346.0
CSH1_k127_2618186_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001659 276.0
CSH1_k127_2618186_5 TIGRFAM indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000003464 190.0
CSH1_k127_2618186_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000009984 184.0
CSH1_k127_2618186_7 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00188 - 1.2.7.7 0.00000000000000000000000000009909 117.0
CSH1_k127_2618186_8 - - - - 0.00001723 51.0
CSH1_k127_2623678_0 GTPase of unknown function C-terminal K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 466.0
CSH1_k127_2623678_1 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 299.0
CSH1_k127_2623678_2 DNA polymerase type-B family K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 301.0
CSH1_k127_2623678_3 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 289.0
CSH1_k127_2623678_4 Helix-hairpin-helix motif K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002582 250.0
CSH1_k127_2623678_5 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000000009062 120.0
CSH1_k127_2623678_6 Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.0000000000114 70.0
CSH1_k127_2623678_7 RNA polymerase K03051 - 2.7.7.6 0.00000000001861 68.0
CSH1_k127_2625210_0 PFAM Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 377.0
CSH1_k127_2625210_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 302.0
CSH1_k127_2625210_2 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 288.0
CSH1_k127_2625210_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000002419 212.0
CSH1_k127_2625210_4 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.0000000000000000000000000007137 117.0
CSH1_k127_26267_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000005259 220.0
CSH1_k127_26267_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000002775 154.0
CSH1_k127_26267_2 - - - - 0.0000000000000000000000000000000003128 142.0
CSH1_k127_26267_3 Winged helix-turn-helix - - - 0.00000000000004705 73.0
CSH1_k127_2663455_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000001121 187.0
CSH1_k127_2663455_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000006141 157.0
CSH1_k127_2663455_2 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000003909 155.0
CSH1_k127_2669063_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000001633 223.0
CSH1_k127_2669063_1 COG2897 Rhodanese-related sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000009736 205.0
CSH1_k127_2669063_2 Transcriptional regulator - - - 0.000000000928 64.0
CSH1_k127_2678514_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 472.0
CSH1_k127_2678514_1 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 302.0
CSH1_k127_2678514_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000009575 153.0
CSH1_k127_2678514_3 PFAM CBS domain - - - 0.000000000000000000449 94.0
CSH1_k127_2678514_4 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.0002356 43.0
CSH1_k127_270898_0 c-type cytochrome biogenesis protein CcmF K02198 - - 0.000000000000000000000000000000000000003763 167.0
CSH1_k127_270898_1 Bacterial Ig-like domain (group 3) - - - 0.0000000000000000000000000000000000005591 155.0
CSH1_k127_270898_2 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000001653 77.0
CSH1_k127_270898_3 glyoxalase III activity - - - 0.00000008658 59.0
CSH1_k127_270898_4 Ferritin-like domain - - - 0.0000004035 58.0
CSH1_k127_2714241_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 307.0
CSH1_k127_2714241_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000002447 222.0
CSH1_k127_2714241_2 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000001065 169.0
CSH1_k127_2722228_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 429.0
CSH1_k127_2722228_1 AraC-like ligand binding domain - - - 0.000002145 55.0
CSH1_k127_2730483_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 467.0
CSH1_k127_2730483_1 Peptidase family M28 K01438 - 3.5.1.16 0.00000000000000000000000001586 117.0
CSH1_k127_2734255_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000009172 231.0
CSH1_k127_2734255_1 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000001619 228.0
CSH1_k127_2734255_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000007828 180.0
CSH1_k127_2734255_3 Bacterial Ig-like domain (group 3) - - - 0.000000000002046 82.0
CSH1_k127_2734255_4 - - - - 0.000001046 54.0
CSH1_k127_2743402_0 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000003771 217.0
CSH1_k127_2743402_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000006088 115.0
CSH1_k127_2743402_2 - - - - 0.0000000002346 72.0
CSH1_k127_2757963_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 433.0
CSH1_k127_2757963_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 403.0
CSH1_k127_2765473_0 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 2.297e-199 632.0
CSH1_k127_2765473_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 430.0
CSH1_k127_2765473_2 Pyridine nucleotide-disulphide oxidoreductase K00384,K03387,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 314.0
CSH1_k127_2765473_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001826 270.0
CSH1_k127_2765473_4 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000000000004262 248.0
CSH1_k127_2765473_5 Universal stress protein family - - - 0.00000000000000000000000000000000000000003755 160.0
CSH1_k127_2765473_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000001583 116.0
CSH1_k127_2765473_7 - - - - 0.000000000000000005394 89.0
CSH1_k127_2765473_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.00000000000004479 74.0
CSH1_k127_2775587_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001057 257.0
CSH1_k127_2775587_1 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000003581 171.0
CSH1_k127_2775587_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000001958 98.0
CSH1_k127_27833_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 284.0
CSH1_k127_27833_1 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000001588 166.0
CSH1_k127_27833_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000001224 86.0
CSH1_k127_27833_3 Belongs to the LeuD family K01704 - 4.2.1.33,4.2.1.35 0.000006437 49.0
CSH1_k127_2806848_0 Fibronectin type III domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007073 291.0
CSH1_k127_2806848_1 response to copper ion - - - 0.00000003359 68.0
CSH1_k127_2827135_0 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 308.0
CSH1_k127_2827135_1 Met-10+ like-protein K15429 - 2.1.1.228 0.00000000000000000000000009526 110.0
CSH1_k127_2827135_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000003834 103.0
CSH1_k127_2842327_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K09759,K22503 - 6.1.1.12,6.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 571.0
CSH1_k127_2842327_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 520.0
CSH1_k127_2842327_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001136 240.0
CSH1_k127_2842327_3 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000000000000000000000004075 139.0
CSH1_k127_2842327_4 Ferredoxin K05337 - - 0.000000003694 61.0
CSH1_k127_2915473_0 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000000000000000000000000000000000000000000009005 227.0
CSH1_k127_2915473_1 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000001446 181.0
CSH1_k127_2915473_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000007853 93.0
CSH1_k127_2922790_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 355.0
CSH1_k127_2922790_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000128 175.0
CSH1_k127_2922790_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000009639 150.0
CSH1_k127_2922790_3 flavin reductase - - - 0.000000000000000000000002577 109.0
CSH1_k127_2922790_4 - - - - 0.0000000000000000000002538 104.0
CSH1_k127_2928275_0 Arylsulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 410.0
CSH1_k127_2928275_1 response to copper ion - - - 0.00001807 54.0
CSH1_k127_2928275_2 TIGRFAM TonB-dependent siderophore receptor K02014 - - 0.00006016 52.0
CSH1_k127_2934419_0 Calcineurin-like phosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000238 208.0
CSH1_k127_2934419_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000004025 197.0
CSH1_k127_2934419_2 exonuclease K07502 - - 0.0000000000000000000000000000000000000000000000006931 186.0
CSH1_k127_2936477_0 Arylsulfatase K01130 GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 352.0
CSH1_k127_2936477_1 COG0306 Phosphate sulphate permeases K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 286.0
CSH1_k127_2936477_2 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000001367 205.0
CSH1_k127_2961913_0 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000002259 174.0
CSH1_k127_2961913_1 TIGRFAM Glycerol-3-phosphate dehydrogenase, anaerobic B subunit K00112 - 1.1.5.3 0.0000000000000002131 93.0
CSH1_k127_2961913_2 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.000000003924 65.0
CSH1_k127_2964060_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 452.0
CSH1_k127_2964060_1 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000005494 227.0
CSH1_k127_2980176_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 375.0
CSH1_k127_2980176_1 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005384 282.0
CSH1_k127_2998943_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 447.0
CSH1_k127_2998943_1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.000000000000000000000000000000000005813 140.0
CSH1_k127_3019695_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.012e-254 808.0
CSH1_k127_3019695_1 Ribbon-helix-helix protein, copG family K07722 GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016151,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032991,GO:0032993,GO:0042802,GO:0043167,GO:0043169,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071840,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000002415 60.0
CSH1_k127_303184_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 351.0
CSH1_k127_303184_1 Protein of unknown function (DUF1614) - - - 0.000000743 59.0
CSH1_k127_308696_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 3.958e-214 677.0
CSH1_k127_308696_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000009577 251.0
CSH1_k127_3123858_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 422.0
CSH1_k127_3123858_1 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 419.0
CSH1_k127_3123858_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003265 284.0
CSH1_k127_3123858_3 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000009733 143.0
CSH1_k127_3123858_4 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000000003331 131.0
CSH1_k127_313797_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000217 229.0
CSH1_k127_313797_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000003388 226.0
CSH1_k127_313797_2 membrane - - - 0.0000000000001826 79.0
CSH1_k127_3140987_0 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000318 215.0
CSH1_k127_3140987_1 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000006105 114.0
CSH1_k127_3140987_2 Amidohydrolase K07045 - - 0.0000000000000000000000000007605 125.0
CSH1_k127_3140987_3 - - - - 0.0000000000002931 81.0
CSH1_k127_3140987_4 membrane - - - 0.00009527 48.0
CSH1_k127_3194637_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.743e-194 621.0
CSH1_k127_3194637_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 329.0
CSH1_k127_3194637_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000001556 188.0
CSH1_k127_3194637_3 GrpB protein - - - 0.00000000000000000000000000000000007472 141.0
CSH1_k127_3194637_4 lactoylglutathione lyase activity - - - 0.000001723 55.0
CSH1_k127_3198436_0 ABC 3 transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005327 285.0
CSH1_k127_3198436_1 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000001476 171.0
CSH1_k127_3198436_2 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000002062 113.0
CSH1_k127_320280_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005634 252.0
CSH1_k127_323402_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 449.0
CSH1_k127_323402_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000005191 188.0
CSH1_k127_323402_2 - - - - 0.00000000000000000004066 94.0
CSH1_k127_323402_3 exosome subunit K07581 - - 0.000000000000000001063 91.0
CSH1_k127_3236705_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 601.0
CSH1_k127_3236705_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 529.0
CSH1_k127_3236705_2 COG0530 Ca2 Na antiporter K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000001106 231.0
CSH1_k127_3236705_3 - - - - 0.0000000000000000000000000626 116.0
CSH1_k127_3245996_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 369.0
CSH1_k127_3245996_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 322.0
CSH1_k127_3245996_2 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000009019 231.0
CSH1_k127_3245996_3 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000005692 171.0
CSH1_k127_3245996_4 Integral membrane protein DUF106 - - - 0.000000000000000000000000000000000003149 145.0
CSH1_k127_326204_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 354.0
CSH1_k127_326204_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001277 269.0
CSH1_k127_326204_2 DNA binding protein K06930 - - 0.00000000000000000000000003917 117.0
CSH1_k127_326204_3 PFAM NADPH-dependent FMN reductase - - - 0.00000000000001935 74.0
CSH1_k127_3273381_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000003236 238.0
CSH1_k127_3273381_1 PhoU domain - - - 0.000000000000000000000000000000000000000000000000001149 189.0
CSH1_k127_3273381_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000002266 173.0
CSH1_k127_3273381_3 PhoU domain - - - 0.000000000000000000000000001047 115.0
CSH1_k127_3273381_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000001994 120.0
CSH1_k127_3273381_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000002635 109.0
CSH1_k127_3273381_6 trans-aconitate 2-methyltransferase activity K00598,K02169 - 2.1.1.144,2.1.1.197 0.000000000000000006397 93.0
CSH1_k127_3279067_0 PFAM GvpD gas vesicle - - - 0.000000000000000000000000000000000000000000000005011 192.0
CSH1_k127_3279067_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000001111 103.0
CSH1_k127_3279067_2 transcriptional regulators - - - 0.000000000000001118 83.0
CSH1_k127_3279067_3 Transcriptional regulators - - - 0.00003438 51.0
CSH1_k127_3294334_0 DNA polymerase type-B family K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 573.0
CSH1_k127_3294334_1 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001245 256.0
CSH1_k127_3294334_2 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000006128 151.0
CSH1_k127_3294334_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000007476 100.0
CSH1_k127_3305065_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 376.0
CSH1_k127_3305065_1 Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 309.0
CSH1_k127_3305065_2 Resolvase, N terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008146 274.0
CSH1_k127_3305065_3 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000001049 252.0
CSH1_k127_3305065_4 Proline dehydrogenase K00318 - - 0.0000000000000000000000004011 116.0
CSH1_k127_3305065_5 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.0000000000000000000001808 105.0
CSH1_k127_3342798_0 Heat shock 70 kDa protein K04043 - - 8.403e-272 849.0
CSH1_k127_3342798_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 4.649e-220 692.0
CSH1_k127_3342798_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000004702 141.0
CSH1_k127_3342798_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000004412 79.0
CSH1_k127_3344634_0 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000669 187.0
CSH1_k127_3344634_1 Glycosyltransferase like family 2 K12992 - - 0.0000000001984 71.0
CSH1_k127_3345066_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000005917 212.0
CSH1_k127_3345066_1 Domain of unknown function (DUF4129) - - - 0.000000009845 66.0
CSH1_k127_337132_0 PEP-utilising enzyme, mobile domain K01006,K01007 - 2.7.9.1,2.7.9.2 5.174e-306 956.0
CSH1_k127_337132_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 466.0
CSH1_k127_337132_2 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 306.0
CSH1_k127_337132_3 PFAM Histone deacetylase K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001466 289.0
CSH1_k127_337132_4 PFAM ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000001062 258.0
CSH1_k127_337132_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000002242 228.0
CSH1_k127_337132_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000002384 199.0
CSH1_k127_337132_7 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000000002748 124.0
CSH1_k127_337132_8 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.000000000000000000000000001214 124.0
CSH1_k127_337132_9 - - - - 0.000000001357 64.0
CSH1_k127_3371529_0 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.00000000000000000000000000000000000005538 147.0
CSH1_k127_3371529_1 CAAX protease self-immunity - - - 0.00000000000000000000000000001943 130.0
CSH1_k127_3381047_0 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000000000001402 228.0
CSH1_k127_3381047_1 RNA secondary structure unwinding K03724 - - 0.00000000000000000000000000000000000074 155.0
CSH1_k127_3383086_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1116.0
CSH1_k127_3383086_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004831 278.0
CSH1_k127_3383086_2 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.00000000004749 64.0
CSH1_k127_3391721_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 1.161e-222 707.0
CSH1_k127_3391721_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000003564 259.0
CSH1_k127_3391721_2 Methyltransferase domain K02493 - 2.1.1.297 0.000000000000000000000000000000000000000002671 161.0
CSH1_k127_3391721_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000001851 159.0
CSH1_k127_3391721_4 PFAM Rhomboid family - - - 0.0000000000000000000000003169 116.0
CSH1_k127_3391721_5 archaeal Zn-finger protein - - - 0.000000000000000002988 90.0
CSH1_k127_3405768_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 588.0
CSH1_k127_3405768_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 452.0
CSH1_k127_3418704_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 492.0
CSH1_k127_3418704_1 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 295.0
CSH1_k127_3418704_2 PFAM response regulator receiver K02485 - - 0.000000000000000000000000000000000000000003541 159.0
CSH1_k127_3418704_3 Histidine phosphatase superfamily (branch 1) - - - 0.00000003163 63.0
CSH1_k127_3422182_0 PAS domain - - - 0.0000000000000000000000000000000000000000000000082 179.0
CSH1_k127_3422182_1 PFAM Pyruvate K00177 - 1.2.7.3 0.000000000000000000000000000000000001694 145.0
CSH1_k127_3422182_2 ATP-grasp domain K22224 - 6.2.1.13 0.0000000000000000001378 93.0
CSH1_k127_344159_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005177 252.0
CSH1_k127_344159_1 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000001733 153.0
CSH1_k127_344159_2 protein conserved in archaea - - - 0.0000000000000000000000003741 108.0
CSH1_k127_344159_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000001675 99.0
CSH1_k127_344159_4 Protein of unknown function (DUF454) K09790 - - 0.0000000000000000001207 94.0
CSH1_k127_3476527_0 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000002626 216.0
CSH1_k127_3476527_1 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000008669 126.0
CSH1_k127_3486131_0 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00467 - 1.13.12.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001593 255.0
CSH1_k127_3486131_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.00000000000000000000000000000000000000000000000000000001342 203.0
CSH1_k127_3486131_2 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000001387 119.0
CSH1_k127_3486197_0 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 308.0
CSH1_k127_3486197_1 Mechanosensitive ion channel K03442,K05802,K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007332 273.0
CSH1_k127_3486197_2 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.000008902 55.0
CSH1_k127_3521548_0 helicase superfamily c-terminal domain K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 501.0
CSH1_k127_3521548_1 - - - - 0.0000000000000002727 82.0
CSH1_k127_3537601_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 497.0
CSH1_k127_3537601_1 - - - - 0.000000000000000000000000000000000000000000000000000007631 196.0
CSH1_k127_3537601_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000168 129.0
CSH1_k127_3537601_3 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.0000000000000000000000000003634 124.0
CSH1_k127_3537601_4 membrane - - - 0.00000003815 62.0
CSH1_k127_3539945_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 492.0
CSH1_k127_3539945_1 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 411.0
CSH1_k127_3539945_2 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 387.0
CSH1_k127_3540272_0 PFAM Glycosyl transferase, group 1 K13668 - 2.4.1.346 0.000000000000000005136 96.0
CSH1_k127_3540272_1 PFAM glycosyl transferase group 1 - - - 0.0000003765 61.0
CSH1_k127_3540876_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 5.204e-225 706.0
CSH1_k127_3540876_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000914 203.0
CSH1_k127_3540876_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000001502 164.0
CSH1_k127_3540876_3 Belongs to the peptidase S8 family - - - 0.0000000000000000003396 95.0
CSH1_k127_3540876_4 Protein of unknown function DUF134 - - - 0.0000003193 53.0
CSH1_k127_3586229_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000312 244.0
CSH1_k127_3586229_1 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.000000000000000000000000000000000000000000000000000000006112 207.0
CSH1_k127_3587336_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1218.0
CSH1_k127_3587336_1 NUDIX domain - - - 0.0000000000000000000001796 102.0
CSH1_k127_3587336_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0001134 46.0
CSH1_k127_3631500_0 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 407.0
CSH1_k127_3631500_1 PQ loop repeat K15383 - - 0.0000000000000001982 81.0
CSH1_k127_3641381_0 NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335,K18331 - 1.12.1.3,1.6.5.3 6.458e-223 707.0
CSH1_k127_3641381_1 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 319.0
CSH1_k127_3641381_2 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000001106 151.0
CSH1_k127_3643892_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 475.0
CSH1_k127_3643892_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 406.0
CSH1_k127_3643892_2 Aminotransferase class-III K00821,K05830 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 383.0
CSH1_k127_3643892_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001034 280.0
CSH1_k127_3643892_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000003422 224.0
CSH1_k127_3649966_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006436 284.0
CSH1_k127_3649966_1 RibD C-terminal domain K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000005298 192.0
CSH1_k127_3649966_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000205 189.0
CSH1_k127_3649966_3 SCP-2 sterol transfer family - - - 0.000000000000000441 82.0
CSH1_k127_3649966_4 - K07138 - - 0.0006648 44.0
CSH1_k127_3654076_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 9.608e-277 871.0
CSH1_k127_3654076_1 PFAM tRNA methyltransferase complex GCD14 subunit K07442 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0031515,GO:0032991,GO:0034708,GO:0043527,GO:0044424,GO:0044444,GO:0044464,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000003909 172.0
CSH1_k127_3654076_2 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000006695 171.0
CSH1_k127_3654076_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000002859 104.0
CSH1_k127_3655411_0 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000001653 154.0
CSH1_k127_3655411_1 OmpA family - - - 0.00000005392 64.0
CSH1_k127_366971_0 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 337.0
CSH1_k127_366971_1 COG0438 Glycosyltransferase K19002 - 2.4.1.337 0.000000000000000002009 88.0
CSH1_k127_368967_0 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 336.0
CSH1_k127_368967_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000005131 234.0
CSH1_k127_368967_2 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000001942 108.0
CSH1_k127_368967_3 - - - - 0.000000000000000000001718 101.0
CSH1_k127_368967_4 TIGRFAM C_GCAxxG_C_C family - - - 0.00000000009948 65.0
CSH1_k127_3691229_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 4.261e-206 678.0
CSH1_k127_3691229_1 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 385.0
CSH1_k127_3691229_2 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009026 404.0
CSH1_k127_3691229_3 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001084 284.0
CSH1_k127_3703152_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 5.871e-222 701.0
CSH1_k127_3703152_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 303.0
CSH1_k127_3703152_2 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000614 223.0
CSH1_k127_3703152_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000000008648 120.0
CSH1_k127_3703152_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000001243 107.0
CSH1_k127_3703152_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000001402 100.0
CSH1_k127_3703152_6 F0F1-type ATP synthase, subunit c archaeal vacuolar-type H -ATPase, subunit K K02124 - - 0.0000000000000000001679 90.0
CSH1_k127_3703152_7 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000002054 81.0
CSH1_k127_372173_0 CobW/HypB/UreG, nucleotide-binding domain - - - 1.051e-201 636.0
CSH1_k127_372173_1 - - - - 0.00000698 50.0
CSH1_k127_3722258_0 Membrane - - - 0.0000000000000000000000000002839 121.0
CSH1_k127_3722258_1 Flavodoxin-like fold - - - 0.00000000000000000000000002855 115.0
CSH1_k127_3722258_2 Sigma-54 interaction domain - - - 0.0000000000000000000001848 113.0
CSH1_k127_3722258_3 PAS domain - - - 0.0000000000000000001606 103.0
CSH1_k127_3722258_4 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000004104 59.0
CSH1_k127_3729013_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 325.0
CSH1_k127_3729013_1 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 296.0
CSH1_k127_3738068_0 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000004108 198.0
CSH1_k127_3738068_1 metal ion binding - - - 0.000000000000000000001821 99.0
CSH1_k127_3738068_2 Belongs to the UPF0235 family K09131 - - 0.0000000000000009364 81.0
CSH1_k127_3738068_3 protein conserved in archaea K09723 - - 0.00000000000003336 82.0
CSH1_k127_3750445_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 437.0
CSH1_k127_3750445_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 414.0
CSH1_k127_3750445_2 Calcineurin-like phosphoesterase superfamily domain K01090 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 368.0
CSH1_k127_3750445_3 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000001577 134.0
CSH1_k127_3831209_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 340.0
CSH1_k127_3831209_1 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000874 196.0
CSH1_k127_3831209_2 Pfam:DUF552 K09152 - - 0.0000000000000000000000002319 109.0
CSH1_k127_38710_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 572.0
CSH1_k127_38710_1 to cation transporters K07244 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 321.0
CSH1_k127_38710_2 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000002681 175.0
CSH1_k127_38710_3 TrkA-C domain protein - - - 0.0000000000000000000002003 99.0
CSH1_k127_38710_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000007937 63.0
CSH1_k127_3909807_0 Bacterial Na+/H+ antiporter B (NhaB) K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000654 260.0
CSH1_k127_3909807_1 LemA family K03744 - - 0.000000000000000000000000007941 117.0
CSH1_k127_3909807_2 Methanol dehydrogenase K06872 - - 0.000000000000000006959 93.0
CSH1_k127_3912362_0 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 332.0
CSH1_k127_3912362_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000001005 173.0
CSH1_k127_3912362_2 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000002397 106.0
CSH1_k127_3928090_0 translation initiation factor 2 subunit alpha K03237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008687 322.0
CSH1_k127_3928090_1 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007028 282.0
CSH1_k127_3928090_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001463 128.0
CSH1_k127_3928090_3 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000009219 85.0
CSH1_k127_3928090_4 Ribosomal protein S27 K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000004649 83.0
CSH1_k127_3928090_5 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000001174 74.0
CSH1_k127_3928090_6 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00006689 49.0
CSH1_k127_3944523_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.554e-208 663.0
CSH1_k127_3944523_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000000000000000000000000000000000000000000002603 177.0
CSH1_k127_3944523_2 Translation initiation factor K03680 - - 0.00000000000003917 83.0
CSH1_k127_3944523_3 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.0000000000007358 74.0
CSH1_k127_3994858_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 9.982e-237 751.0
CSH1_k127_3994858_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000006013 203.0
CSH1_k127_4018051_0 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000002735 222.0
CSH1_k127_4018051_1 Uroporphyrinogen decarboxylase K14080 - 2.1.1.246 0.00000000000000000000000569 114.0
CSH1_k127_4018051_2 PFAM Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.0000000000000000000002508 98.0
CSH1_k127_4019866_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 478.0
CSH1_k127_4019866_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000004791 207.0
CSH1_k127_4019866_2 Belongs to the UPF0200 family - - - 0.00000000000000003969 86.0
CSH1_k127_4024219_0 PFAM Phosphatidylglycerophosphatase A - - - 0.000000000000000000000000006366 123.0
CSH1_k127_4024219_1 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000003343 102.0
CSH1_k127_4024219_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000005617 84.0
CSH1_k127_4024219_3 Adenosylcobinamide amidohydrolase - - - 0.00000000000001793 85.0
CSH1_k127_4025345_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000009863 223.0
CSH1_k127_4025345_1 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000000000008025 207.0
CSH1_k127_4025608_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 350.0
CSH1_k127_4025608_1 transporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000007916 222.0
CSH1_k127_4025608_2 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000001883 135.0
CSH1_k127_4047997_0 DNA packaging K06909 - - 0.000000004451 68.0
CSH1_k127_4048168_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001941 265.0
CSH1_k127_4048168_1 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000007385 172.0
CSH1_k127_4049367_0 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001208 256.0
CSH1_k127_4049367_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000328 228.0
CSH1_k127_4049367_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000003793 171.0
CSH1_k127_4049367_3 Staygreen protein K22013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006787,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009536,GO:0009579,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010271,GO:0015994,GO:0015996,GO:0016020,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031976,GO:0031984,GO:0033013,GO:0033015,GO:0034357,GO:0034641,GO:0042440,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044270,GO:0044422,GO:0044424,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046149,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051187,GO:0051193,GO:0051195,GO:0055035,GO:0065007,GO:0071704,GO:0090056,GO:1901360,GO:1901361,GO:1901401,GO:1901402,GO:1901404,GO:1901405,GO:1901564,GO:1901565,GO:1901575,GO:1903647 4.99.1.10 0.00000000000000000000000000000003369 130.0
CSH1_k127_4068559_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 465.0
CSH1_k127_4068559_1 Amino acid kinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 394.0
CSH1_k127_4068559_10 - - - - 0.0000000000005724 75.0
CSH1_k127_4068559_2 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 383.0
CSH1_k127_4068559_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 318.0
CSH1_k127_4068559_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 317.0
CSH1_k127_4068559_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000001738 233.0
CSH1_k127_4068559_6 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000001203 228.0
CSH1_k127_4068559_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000009663 219.0
CSH1_k127_4068559_8 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000000000000000000000000000613 199.0
CSH1_k127_4068559_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000005066 132.0
CSH1_k127_4084189_0 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003577 248.0
CSH1_k127_4084189_1 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000001411 124.0
CSH1_k127_4084189_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.0000000000000000000000007098 110.0
CSH1_k127_4088475_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 319.0
CSH1_k127_4088475_1 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000002313 137.0
CSH1_k127_4093641_0 PFAM Hydantoinase oxoprolinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 316.0
CSH1_k127_4093641_1 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000007663 151.0
CSH1_k127_4101471_0 Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes K09613 GO:0000003,GO:0000338,GO:0000749,GO:0000754,GO:0000909,GO:0003006,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008180,GO:0008233,GO:0008234,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0010893,GO:0016787,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019538,GO:0019783,GO:0019784,GO:0019953,GO:0022414,GO:0023051,GO:0023058,GO:0030447,GO:0030448,GO:0030582,GO:0030584,GO:0031136,GO:0031137,GO:0031139,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032443,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0036211,GO:0040007,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045116,GO:0045834,GO:0045940,GO:0046889,GO:0046890,GO:0046999,GO:0048518,GO:0048522,GO:0048583,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050810,GO:0050896,GO:0051704,GO:0051716,GO:0061458,GO:0062012,GO:0062013,GO:0065007,GO:0070011,GO:0070452,GO:0070646,GO:0070647,GO:0070791,GO:0070887,GO:0071310,GO:0071444,GO:0071704,GO:0075259,GO:0080090,GO:0106118,GO:0106120,GO:0140096,GO:1901564,GO:1902930,GO:1902932,GO:2000241,GO:2000243 - 0.0000000000002306 78.0
CSH1_k127_4101471_1 SIS domain K08094 - 5.3.1.27 0.0000000004449 60.0
CSH1_k127_4101471_2 NEDD8 transferase activity K00053,K00573,K00698,K10579 GO:0003674,GO:0003824,GO:0004842,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008589,GO:0009719,GO:0009725,GO:0009733,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010646,GO:0010648,GO:0010941,GO:0010942,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019788,GO:0023051,GO:0023057,GO:0031974,GO:0031981,GO:0032446,GO:0036211,GO:0042221,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043523,GO:0043525,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045116,GO:0045879,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0061650,GO:0061654,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0140096,GO:1901214,GO:1901216,GO:1901564 1.1.1.86,2.1.1.77,2.4.1.16 0.000000008607 63.0
CSH1_k127_4103672_0 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000001335 235.0
CSH1_k127_4103672_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000126 217.0
CSH1_k127_4103672_2 KaiC K07331 - - 0.00000000000000000000000000000000000000000000000005411 186.0
CSH1_k127_4103672_3 Transcriptional regulator PadR-like family - - - 0.0000000000000001641 83.0
CSH1_k127_4103672_4 - - - - 0.0000004926 57.0
CSH1_k127_4103672_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.00005762 51.0
CSH1_k127_4105895_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 6.13e-233 753.0
CSH1_k127_4105895_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000001233 216.0
CSH1_k127_4110448_0 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 325.0
CSH1_k127_4110448_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 292.0
CSH1_k127_4110448_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003309 256.0
CSH1_k127_4110448_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000002972 89.0
CSH1_k127_4126713_0 MCM OB domain K10726 - - 0.00000000000000000000000000000000000000000000000000000000004219 212.0
CSH1_k127_4126713_1 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000000001542 177.0
CSH1_k127_4126713_2 RDD family - - - 0.0001803 47.0
CSH1_k127_413752_0 Aldehyde dehydrogenase family K15515 - 1.2.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 479.0
CSH1_k127_413752_1 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 393.0
CSH1_k127_413752_2 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.0000000000000000000000000000000000000000000000008863 181.0
CSH1_k127_4192071_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 353.0
CSH1_k127_4192071_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000005131 256.0
CSH1_k127_4209403_0 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 386.0
CSH1_k127_4209403_1 - - - - 0.00000000000000000000007504 104.0
CSH1_k127_4209403_2 toxin activity - - - 0.0000000006479 63.0
CSH1_k127_4210991_0 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 471.0
CSH1_k127_4210991_1 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 342.0
CSH1_k127_4213927_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 377.0
CSH1_k127_4213927_1 Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 345.0
CSH1_k127_4213927_2 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000003139 166.0
CSH1_k127_4213927_3 Protein of unknown function (DUF2769) - - - 0.0000000002195 64.0
CSH1_k127_4213927_4 - K13652 - - 0.00000001519 59.0
CSH1_k127_4262168_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 2.775e-204 653.0
CSH1_k127_4262168_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000076 177.0
CSH1_k127_4262168_2 COG1522 Transcriptional regulators K03718 - - 0.0000000000000000000000000000000000000000000000921 173.0
CSH1_k127_4262168_3 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000007358 169.0
CSH1_k127_4262168_4 Transcriptional regulator K03724 - - 0.000000000004475 73.0
CSH1_k127_4274179_0 Peptidoglycan-binding domain 1 protein K07011 - - 6.715e-215 683.0
CSH1_k127_4275032_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000008526 227.0
CSH1_k127_4275032_1 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000002383 138.0
CSH1_k127_4281958_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 372.0
CSH1_k127_4281958_1 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000009223 184.0
CSH1_k127_4281958_2 mechanosensitive ion channel K16053 - - 0.000001903 55.0
CSH1_k127_428320_0 ABC-type Fe3 transport system permease component K02053,K02054,K02063 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 502.0
CSH1_k127_428320_1 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000004552 188.0
CSH1_k127_428320_2 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000004061 125.0
CSH1_k127_4303191_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K03698 - - 0.000000000000000000000000000000000000000000000000000000000000188 224.0
CSH1_k127_4303191_1 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000000006203 150.0
CSH1_k127_4308674_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 325.0
CSH1_k127_4308674_1 NMD3 family K07562 - - 0.000000000000000000000000000000000000000000000000002351 190.0
CSH1_k127_4308674_2 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000004915 115.0
CSH1_k127_4324479_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 570.0
CSH1_k127_4324479_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 525.0
CSH1_k127_4324479_2 Putative diphthamide synthesis protein K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 308.0
CSH1_k127_4324479_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 297.0
CSH1_k127_4324479_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000003973 248.0
CSH1_k127_4324479_5 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003641 215.0
CSH1_k127_4324479_6 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000002183 211.0
CSH1_k127_4324479_7 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000001516 164.0
CSH1_k127_4328751_0 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 341.0
CSH1_k127_4328751_1 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000003872 97.0
CSH1_k127_4328751_2 Belongs to the UPF0434 family - - - 0.000000000000375 74.0
CSH1_k127_4364390_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 329.0
CSH1_k127_4364390_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000004065 111.0
CSH1_k127_4364390_2 regulatory protein, arsR - - - 0.0000000000000002482 89.0
CSH1_k127_4365307_0 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000282 251.0
CSH1_k127_4365307_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000001582 102.0
CSH1_k127_4365307_2 - - - - 0.0000000000001881 83.0
CSH1_k127_4365307_3 3-oxoacyl- acyl-carrier protein reductase K00059 - 1.1.1.100 0.000000000001174 75.0
CSH1_k127_4392318_0 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000239 264.0
CSH1_k127_4392318_1 Universal stress protein family - - - 0.0000000000000008375 83.0
CSH1_k127_4392318_2 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.000000000000001213 79.0
CSH1_k127_4397059_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 319.0
CSH1_k127_4397059_1 shikimate kinase activity K00891 - 2.7.1.71 0.0000000000000000000000003463 109.0
CSH1_k127_4407029_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001286 245.0
CSH1_k127_4407029_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000001493 121.0
CSH1_k127_4407029_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000001656 77.0
CSH1_k127_4424744_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 362.0
CSH1_k127_4424744_1 Glycosyltransferase like family 2 K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000176 266.0
CSH1_k127_4424744_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000003325 175.0
CSH1_k127_4424744_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000001336 170.0
CSH1_k127_4424744_4 PFAM polysaccharide biosynthesis protein - - - 0.00000000000004066 85.0
CSH1_k127_4424889_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601,K08965 - 4.1.1.39,5.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 512.0
CSH1_k127_4424889_1 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 314.0
CSH1_k127_4424889_2 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.00000000000000000000000000000000000000006458 157.0
CSH1_k127_4431606_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 377.0
CSH1_k127_4431606_1 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000008037 249.0
CSH1_k127_4431606_2 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.00000000000000000000000000000001158 132.0
CSH1_k127_4431606_3 PFAM EamA-like transporter family - - - 0.0000000000000000000001604 103.0
CSH1_k127_446181_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000001495 145.0
CSH1_k127_446181_2 AsnC family transcriptional regulator K03719 - - 0.00085 45.0
CSH1_k127_4501487_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 499.0
CSH1_k127_4501487_1 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 341.0
CSH1_k127_4517724_0 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000005249 238.0
CSH1_k127_4517724_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000001741 213.0
CSH1_k127_4520552_0 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 444.0
CSH1_k127_4520552_1 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000003788 189.0
CSH1_k127_4520552_2 NMT1-like family K02051 - - 0.000000000001691 73.0
CSH1_k127_4520552_3 - - - - 0.0000001401 57.0
CSH1_k127_4527916_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.212e-263 833.0
CSH1_k127_4527916_1 FAD binding domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000002114 271.0
CSH1_k127_4527916_2 pfam yhs - - - 0.0000000000000000003795 88.0
CSH1_k127_4528306_0 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000005202 90.0
CSH1_k127_4528306_1 FAD dependent oxidoreductase - - - 0.00000000000001717 86.0
CSH1_k127_4528514_0 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000008117 264.0
CSH1_k127_4528514_1 Involved in the catabolism of quinolinic acid (QA) K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000008162 235.0
CSH1_k127_4528514_2 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000004215 224.0
CSH1_k127_4528514_3 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000005287 189.0
CSH1_k127_4528514_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000004046 135.0
CSH1_k127_4528514_5 Heterodisulfide reductase subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000008364 113.0
CSH1_k127_4528514_6 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000004536 85.0
CSH1_k127_4528514_7 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.0000000000002033 72.0
CSH1_k127_4549066_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 424.0
CSH1_k127_4549066_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000006995 238.0
CSH1_k127_4571072_0 4Fe-4S single cluster domain K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 378.0
CSH1_k127_4571072_1 Participates in transcription termination K02600 - - 0.0000000000000000000000000000000000000000000000000000000681 201.0
CSH1_k127_4571072_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000001111 190.0
CSH1_k127_4571072_3 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000001048 124.0
CSH1_k127_4571072_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00001521 52.0
CSH1_k127_458172_0 ATPases associated with a variety of cellular activities K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 344.0
CSH1_k127_458172_1 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000008855 164.0
CSH1_k127_458172_2 ABC-2 type transporter K09690 - - 0.000000000000000000000003431 104.0
CSH1_k127_4613932_0 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000208 246.0
CSH1_k127_4613932_1 cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000001383 113.0
CSH1_k127_4613932_2 Psort location Extracellular, score - - - 0.00001222 58.0
CSH1_k127_461942_0 AAA domain K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 611.0
CSH1_k127_461942_1 Toprim domain K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 438.0
CSH1_k127_461942_2 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.0000000000000000000000001845 116.0
CSH1_k127_461942_3 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000001248 102.0
CSH1_k127_4653806_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 387.0
CSH1_k127_4653806_1 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000002575 184.0
CSH1_k127_4653806_2 major facilitator superfamily - - - 0.0000000000000000000000004881 118.0
CSH1_k127_4675475_0 Acyl-CoA synthetase (NDP forming) K09181 - - 1.706e-200 646.0
CSH1_k127_4675475_1 COG0857 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000166 244.0
CSH1_k127_4697346_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 590.0
CSH1_k127_4697346_1 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.0000000000000000000000000000000000000000000002393 175.0
CSH1_k127_4717146_0 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 312.0
CSH1_k127_4717146_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01464,K01465,K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.2,3.5.2.3,3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000003597 262.0
CSH1_k127_4717146_2 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000009649 151.0
CSH1_k127_471909_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 2.078e-230 746.0
CSH1_k127_471909_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 478.0
CSH1_k127_471909_10 - - - - 0.0000000000002958 74.0
CSH1_k127_471909_2 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 397.0
CSH1_k127_471909_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 394.0
CSH1_k127_471909_4 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000001844 176.0
CSH1_k127_471909_5 V4R K07013 - - 0.000000000000000000000000000000000000000000001167 175.0
CSH1_k127_471909_6 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000001604 162.0
CSH1_k127_471909_7 Methyltransferase domain - - - 0.0000000000000000000000000000002126 129.0
CSH1_k127_471909_8 membrane - - - 0.00000000000000000000000007559 114.0
CSH1_k127_471909_9 Phosphate transport regulator K07220 - - 0.000000000000000002654 89.0
CSH1_k127_4767219_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000006904 143.0
CSH1_k127_4767219_1 cobalamin binding K00548 - 2.1.1.13 0.000000000000000000008563 94.0
CSH1_k127_4767219_2 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000000000002567 80.0
CSH1_k127_4767570_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 308.0
CSH1_k127_4767570_1 Putative TM nitroreductase - - - 0.000000000006455 67.0
CSH1_k127_4777388_0 Fumarate reductase succinate dehydrogenase flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 306.0
CSH1_k127_4777388_1 COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 296.0
CSH1_k127_4777388_2 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 287.0
CSH1_k127_4788138_0 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007516 250.0
CSH1_k127_4788138_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000001803 194.0
CSH1_k127_482771_0 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 321.0
CSH1_k127_482771_1 TIGR00268 family K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002588 254.0
CSH1_k127_482771_2 AIR carboxylase K06898 - - 0.000000000000000000000002205 106.0
CSH1_k127_4830861_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 5.015e-300 938.0
CSH1_k127_4830861_1 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000000436 239.0
CSH1_k127_4830861_2 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000008794 194.0
CSH1_k127_4830861_3 PRC-barrel domain - - - 0.0000000000000000000000001516 108.0
CSH1_k127_4830861_4 Glycosyl transferase family 41 K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.00000000004401 71.0
CSH1_k127_4830861_5 Titin-like K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.0000000003344 72.0
CSH1_k127_483619_0 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000001056 241.0
CSH1_k127_483619_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000154 154.0
CSH1_k127_483619_2 Helix-turn-helix domain - - - 0.00000000000000005958 85.0
CSH1_k127_4858335_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001301 270.0
CSH1_k127_4858335_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000001641 231.0
CSH1_k127_4858335_2 redox-active disulfide protein 2 - - - 0.000000000000000009096 85.0
CSH1_k127_4872480_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001244 296.0
CSH1_k127_4872480_1 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000001775 244.0
CSH1_k127_4872480_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000222 219.0
CSH1_k127_4876415_0 Universal stress protein family - - - 0.000000000000000000000006867 106.0
CSH1_k127_4876415_1 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000006792 48.0
CSH1_k127_4876415_2 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0001363 53.0
CSH1_k127_488361_0 PFAM ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 344.0
CSH1_k127_488361_1 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000005292 215.0
CSH1_k127_488361_2 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000008403 190.0
CSH1_k127_488361_3 PFAM SufBD protein K07033 - - 0.000000000000000000000000000005995 124.0
CSH1_k127_488361_4 parallel beta-helix repeat K03671 - - 0.0000526 55.0
CSH1_k127_4884799_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 9.607e-211 672.0
CSH1_k127_4884799_1 helicase superfamily c-terminal domain K10896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 438.0
CSH1_k127_4898865_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 442.0
CSH1_k127_4898865_1 PP-loop family - - - 0.000000000000000000000001901 106.0
CSH1_k127_4898865_2 Ribosomal_L40e K02927 - - 0.000000000000002187 78.0
CSH1_k127_492470_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000005247 180.0
CSH1_k127_492470_1 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000007335 119.0
CSH1_k127_492470_2 formylmethanofuran dehydrogenase, subunit E - - - 0.0000000000000000005673 92.0
CSH1_k127_4945357_0 COG0531 Amino acid transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 403.0
CSH1_k127_4945357_1 Methanogenesis marker protein 8 - - - 0.00000000000000000000000000000000000000000000000000004871 199.0
CSH1_k127_4945357_2 Iron-sulfur cluster assembly accessory protein K13628,K15724 - - 0.000000000000000000000000000000006079 130.0
CSH1_k127_4945357_3 DHHA1 domain K07463 - - 0.000000001991 69.0
CSH1_k127_4945357_4 DEAD DEAH box helicase domain protein K10896 - - 0.000002395 51.0
CSH1_k127_4945357_5 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0001086 51.0
CSH1_k127_495845_0 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K00343,K22169 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 411.0
CSH1_k127_495845_1 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342,K22168 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 401.0
CSH1_k127_495845_2 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000002161 253.0
CSH1_k127_495845_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000006014 222.0
CSH1_k127_49597_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 389.0
CSH1_k127_49597_1 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000000000000000000000008272 222.0
CSH1_k127_49597_2 sulfur carrier activity K07112 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000003809 92.0
CSH1_k127_49597_3 DegT/DnrJ/EryC1/StrS aminotransferase family K04487 - 2.8.1.7 0.0000000004463 62.0
CSH1_k127_4960251_0 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 378.0
CSH1_k127_4960251_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000003549 190.0
CSH1_k127_4960251_2 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000002476 177.0
CSH1_k127_4960451_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 341.0
CSH1_k127_4960451_1 PFAM NADH ubiquinone oxidoreductase, 20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 321.0
CSH1_k127_4960451_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000000000000000000002404 171.0
CSH1_k127_4960451_3 PFAM NADH Ubiquinone plastoquinone (complex I) K05559,K14086 - - 0.00000000000000000000000765 108.0
CSH1_k127_4971720_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 477.0
CSH1_k127_4971720_1 Rubrerythrin - - - 0.0000000000000000000000000002838 117.0
CSH1_k127_4986633_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 312.0
CSH1_k127_4986633_1 Acetolactate synthase small K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000236 120.0
CSH1_k127_4986633_2 ABC transporter, ATP-binding protein K16960 - - 0.0000002405 54.0
CSH1_k127_5010793_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 469.0
CSH1_k127_5010793_1 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000006799 212.0
CSH1_k127_5125501_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 591.0
CSH1_k127_5125501_1 Pyruvoyl-dependent arginine decarboxylase K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000005513 203.0
CSH1_k127_5125501_2 Insulinase (Peptidase family M16) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000001188 172.0
CSH1_k127_5125501_3 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000003918 171.0
CSH1_k127_5125501_4 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000001346 131.0
CSH1_k127_5125501_5 - - - - 0.0000000000000000000000003884 114.0
CSH1_k127_5125501_6 cheY-homologous receiver domain - - - 0.00000000000000004948 92.0
CSH1_k127_5125501_7 IPT TIG domain - - - 0.000009267 57.0
CSH1_k127_5131117_0 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003261 284.0
CSH1_k127_5131117_1 Ferrous iron transport B domain protein K04759 - - 0.0000000000000000000000000000000000000000000000000005165 196.0
CSH1_k127_5131117_2 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000002269 178.0
CSH1_k127_5131117_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000796 81.0
CSH1_k127_5131247_0 Protein of unknown function, DUF255 K06888 - - 2.728e-194 624.0
CSH1_k127_5131247_1 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 292.0
CSH1_k127_5131247_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000009101 229.0
CSH1_k127_5131247_3 Domain of unknown function (DUF4443) - - - 0.0000000000000000000000000000000000000000000004054 173.0
CSH1_k127_5131247_4 - - - - 0.00000000000000002177 88.0
CSH1_k127_5154409_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 617.0
CSH1_k127_5223662_0 Radical SAM domain protein K02585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 430.0
CSH1_k127_5223662_1 Protein of unknown function (DUF763) K09003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 405.0
CSH1_k127_5223662_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000005899 242.0
CSH1_k127_5223662_3 Belongs to the UPF0216 family K09737 - - 0.0000000000000006094 83.0
CSH1_k127_5223662_4 COG NOG14600 non supervised orthologous group - - - 0.0000001608 57.0
CSH1_k127_5227165_0 PFAM ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001387 270.0
CSH1_k127_5227165_1 Phosphoribosyl transferase domain K00769,K07101 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000201 262.0
CSH1_k127_5227165_2 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000003372 234.0
CSH1_k127_5227165_3 Protein of unknown function TPD sequence-motif - - - 0.000000000000000000000000000000000000000000000000000000000000000003901 234.0
CSH1_k127_5227165_4 May catalyze a purine salvage reaction, the substrate is K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000004243 207.0
CSH1_k127_5227165_5 Belongs to the UPF0248 family K09715 - - 0.000000000002419 70.0
CSH1_k127_5227165_6 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.0000009846 57.0
CSH1_k127_5227872_0 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.000000000000000000000000005781 115.0
CSH1_k127_5227872_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000002285 114.0
CSH1_k127_5227872_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000004375 112.0
CSH1_k127_5227872_3 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000003832 87.0
CSH1_k127_5249844_0 Methyltransferase domain K07579 - - 0.00000000000000000000000000000000000000000000000000000001705 203.0
CSH1_k127_5249844_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000006373 203.0
CSH1_k127_5249844_2 PFAM Glutamine amidotransferase, class-II - - - 0.0000000000000000000000000000000000000000000000000000003103 197.0
CSH1_k127_5249844_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000000000000001636 188.0
CSH1_k127_5249844_4 Glutamate synthase (NADPH) GltB1 subunit - - - 0.00000000000000000000000000000008798 131.0
CSH1_k127_5249844_5 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000003631 123.0
CSH1_k127_5249844_6 - - - - 0.00000000000000000000005397 101.0
CSH1_k127_5249844_7 - - - - 0.00000000000000003541 84.0
CSH1_k127_5280424_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 484.0
CSH1_k127_5280424_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000005698 216.0
CSH1_k127_5362261_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 551.0
CSH1_k127_5362261_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 325.0
CSH1_k127_5362261_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000001956 214.0
CSH1_k127_5362261_3 Major intrinsic protein - - - 0.00000000000000000000000000000000000000001291 162.0
CSH1_k127_5362261_4 Protein of unknown function (DUF357) K09728 - - 0.000683 47.0
CSH1_k127_536300_0 Domain of unknown function (DUF4445) - - - 5.647e-215 681.0
CSH1_k127_536300_1 Methanol-cobalamin methyltransferase B subunit K04480 - 2.1.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 576.0
CSH1_k127_536300_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000008747 166.0
CSH1_k127_536300_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.0000000000000000000000000000000000000000002907 164.0
CSH1_k127_536300_4 acetyl-CoA catabolic process K00197,K03616 - 2.1.1.245 0.0000000000000000000000000000000002012 139.0
CSH1_k127_536300_5 corrinoid protein K14081 - - 0.00000000005432 64.0
CSH1_k127_536591_0 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 315.0
CSH1_k127_5371698_0 PFAM Radical SAM K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 407.0
CSH1_k127_5371698_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000001135 201.0
CSH1_k127_5371698_2 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000009027 134.0
CSH1_k127_5371698_3 - - - - 0.00000000000000001635 85.0
CSH1_k127_5371698_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000001842 62.0
CSH1_k127_5381407_0 Uncharacterized protein family UPF0004 K15865 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 324.0
CSH1_k127_5381407_1 nitroreductase - - - 0.0000000000000000000000000000000000000000000000007298 179.0
CSH1_k127_5381407_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000001262 129.0
CSH1_k127_5385693_0 Carbamoyl-phosphate synthase L chain, ATP binding domain - - - 0.00000000000000000000000000000000000000000000000000001503 204.0
CSH1_k127_5385693_1 ATP-grasp domain - - - 0.000000000000000000001711 103.0
CSH1_k127_5392217_0 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000001577 150.0
CSH1_k127_5392217_1 Histidine kinase-like ATPases - - - 0.0000000000000000000003236 105.0
CSH1_k127_5392217_2 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000009103 85.0
CSH1_k127_5408136_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 529.0
CSH1_k127_5408136_1 DnaB-like helicase C terminal domain - - - 0.000000000000000000000000000000000004226 146.0
CSH1_k127_5408136_2 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000597 121.0
CSH1_k127_5408136_3 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000005761 87.0
CSH1_k127_5418604_0 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 389.0
CSH1_k127_5418604_1 PFAM Aminotransferase class I and II K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 302.0
CSH1_k127_5418604_2 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000004317 237.0
CSH1_k127_5418604_3 methyltransferase - - - 0.0000000000000000002457 97.0
CSH1_k127_5418604_4 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000001167 91.0
CSH1_k127_5440606_0 Leucine rich repeats (6 copies) - - - 0.000000000000000000000000000000000000000000000599 181.0
CSH1_k127_5440606_1 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000003147 167.0
CSH1_k127_5440606_2 PKD domain - - - 0.0000000003787 72.0
CSH1_k127_5465753_0 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 456.0
CSH1_k127_5465753_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008188 277.0
CSH1_k127_5465753_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000002906 223.0
CSH1_k127_5465753_3 DNA repair and recombination protein RadB K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000005688 203.0
CSH1_k127_5465753_4 PFAM DoxX family protein K16937 - 1.8.5.2 0.00000000000000000000000000000000000000000000000002828 184.0
CSH1_k127_5465753_5 Major facilitator superfamily - - - 0.0000000000000000000000000000000000357 150.0
CSH1_k127_5472349_0 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000001573 194.0
CSH1_k127_5472349_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000003132 165.0
CSH1_k127_5472349_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000007796 155.0
CSH1_k127_5512768_0 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 361.0
CSH1_k127_5550353_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 1.326e-195 625.0
CSH1_k127_5563117_0 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 370.0
CSH1_k127_5563117_1 - - - - 0.00000002055 60.0
CSH1_k127_5566010_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002616 279.0
CSH1_k127_5566010_1 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000018 171.0
CSH1_k127_5566010_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00005332 45.0
CSH1_k127_5589587_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1029.0
CSH1_k127_5589587_1 ATP-grasp enzyme - - - 0.000000000000000000000000001669 119.0
CSH1_k127_5592753_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 566.0
CSH1_k127_5592753_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 344.0
CSH1_k127_5596270_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 586.0
CSH1_k127_5596270_1 NADH-quinone oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001256 272.0
CSH1_k127_5596270_2 Molydopterin dinucleotide binding domain K00123,K00302,K10814 - 1.17.1.9,1.4.99.5,1.5.3.1 0.000000000000000009532 95.0
CSH1_k127_5601242_0 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000002875 133.0
CSH1_k127_5601242_1 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000002508 130.0
CSH1_k127_5601242_2 Major Facilitator Superfamily - - - 0.0001147 45.0
CSH1_k127_5607853_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 526.0
CSH1_k127_5607853_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 484.0
CSH1_k127_5607853_2 archaeal coiled-coil protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000005434 244.0
CSH1_k127_5607853_3 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.00000000000000000000000000000000000000000000000000000000000000000001315 240.0
CSH1_k127_5607853_4 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0000007764 55.0
CSH1_k127_5615878_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 407.0
CSH1_k127_5615878_1 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000279 271.0
CSH1_k127_5615878_2 PFAM TfuA domain protein, core - - - 0.00000000000000000000000000000000000000000000004979 177.0
CSH1_k127_5615878_3 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.00000000000000000000000000000001506 135.0
CSH1_k127_5615878_4 Transcriptional - - - 0.000000000001255 74.0
CSH1_k127_5638460_0 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 539.0
CSH1_k127_5638460_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 321.0
CSH1_k127_5638460_2 Peptidase dimerisation domain K01439 - 3.5.1.18 0.000000001622 61.0
CSH1_k127_5640194_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 332.0
CSH1_k127_5640194_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 286.0
CSH1_k127_5640194_2 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000003504 237.0
CSH1_k127_5640194_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000006411 199.0
CSH1_k127_5667469_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.0000000000000000000000000000000001395 137.0
CSH1_k127_5677707_0 Quinolinate phosphoribosyl transferase, C-terminal domain K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 426.0
CSH1_k127_5677707_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 330.0
CSH1_k127_5677707_2 OsmC-like protein - - - 0.000000000000000000000000000000000006218 141.0
CSH1_k127_5677707_3 Cytochrome b5-like Heme/Steroid binding domain - - - 0.00000000000000000000005661 99.0
CSH1_k127_5693356_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 363.0
CSH1_k127_5693356_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 344.0
CSH1_k127_5693356_2 - - - - 0.0000000000001316 74.0
CSH1_k127_5697128_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 290.0
CSH1_k127_5697128_1 PFAM band 7 protein - - - 0.000000009088 59.0
CSH1_k127_5697128_2 MacB-like periplasmic core domain K02004 - - 0.0008535 47.0
CSH1_k127_5711227_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 392.0
CSH1_k127_5711227_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000554 137.0
CSH1_k127_5711227_2 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000003617 132.0
CSH1_k127_572694_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 460.0
CSH1_k127_5728555_0 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 407.0
CSH1_k127_5728555_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001644 276.0
CSH1_k127_5728555_2 PFAM Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000000000009213 222.0
CSH1_k127_5728555_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0004649 49.0
CSH1_k127_5760268_0 Belongs to the glutamate synthase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 587.0
CSH1_k127_5760268_1 PFAM glutamate synthase alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000003963 214.0
CSH1_k127_5760268_2 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000005166 48.0
CSH1_k127_5760268_3 glutamine amidotransferase - - - 0.0008264 43.0
CSH1_k127_5774215_0 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 358.0
CSH1_k127_5774215_1 methanogenesis marker protein 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 347.0
CSH1_k127_5774215_2 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.0000000000000000000000000000000002688 145.0
CSH1_k127_5781139_0 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 291.0
CSH1_k127_5781139_1 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.0000000000000000000000000000000000001507 144.0
CSH1_k127_5781139_2 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016043,GO:0016272,GO:0022607,GO:0032991,GO:0034622,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051087,GO:0051131,GO:0065003,GO:0071840 - 0.0000000000000000000000000001628 118.0
CSH1_k127_5781139_3 binds to the 23S rRNA K02921 - - 0.0000000000000000000000000009858 114.0
CSH1_k127_5781139_4 Transcription factor Pcc1 K09741 - - 0.00000000008566 67.0
CSH1_k127_5781139_5 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.0000000001824 64.0
CSH1_k127_5820287_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000485 198.0
CSH1_k127_5820287_1 amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000001576 158.0
CSH1_k127_5840592_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000002277 241.0
CSH1_k127_5840592_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000001125 167.0
CSH1_k127_5871487_0 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 299.0
CSH1_k127_5871487_1 protein conserved in bacteria - - - 0.00000000000000000000000000009814 129.0
CSH1_k127_5871487_2 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000194 59.0
CSH1_k127_5916007_0 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006839 254.0
CSH1_k127_5916007_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006896 249.0
CSH1_k127_5916007_2 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000003602 199.0
CSH1_k127_5916007_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000397 84.0
CSH1_k127_5923793_0 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 304.0
CSH1_k127_5923793_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000001002 164.0
CSH1_k127_5923793_2 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000003327 142.0
CSH1_k127_627823_0 PFAM Major Facilitator Superfamily K19576 - - 0.000000000000000000000000000000000000000000000000000000000000001436 232.0
CSH1_k127_627823_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.0000000000000000000000000000000000000000000001337 171.0
CSH1_k127_627823_2 - - - - 0.0000006437 54.0
CSH1_k127_627885_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 481.0
CSH1_k127_681851_0 Abc transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000009513 213.0
CSH1_k127_681851_1 PFAM ABC-3 protein K09816 - - 0.00000000000000000000000000000000000000000000000000000006566 207.0
CSH1_k127_684446_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001977 237.0
CSH1_k127_684446_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 0.00000000000000000000000000002962 120.0
CSH1_k127_684446_2 ASNC family K03718 - - 0.0000002358 59.0
CSH1_k127_716629_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 470.0
CSH1_k127_724801_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 2.101e-222 702.0
CSH1_k127_724801_1 Archaeal Nre, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 532.0
CSH1_k127_724801_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000006173 222.0
CSH1_k127_763256_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 470.0
CSH1_k127_763256_1 COG0306 Phosphate sulphate permeases K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000001372 126.0
CSH1_k127_763256_2 glucosylceramidase activity - - - 0.000000000000000000000000000001239 124.0
CSH1_k127_763256_3 THUMP domain K06963 - - 0.000000008938 64.0
CSH1_k127_763256_4 - - - - 0.0000001696 61.0
CSH1_k127_763256_5 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000008183 49.0
CSH1_k127_765627_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 556.0
CSH1_k127_765627_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 442.0
CSH1_k127_777042_0 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 347.0
CSH1_k127_777042_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000002109 192.0
CSH1_k127_818694_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 325.0
CSH1_k127_818694_1 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000008537 214.0
CSH1_k127_818694_2 Methyltransferase MtaA CmuA family K01599 - 4.1.1.37 0.00000009226 61.0
CSH1_k127_829669_0 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000001738 218.0
CSH1_k127_829669_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000003875 214.0
CSH1_k127_829669_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000006149 124.0
CSH1_k127_85499_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000002052 237.0
CSH1_k127_85499_1 Uroporphyrinogen decarboxylase (URO-D) K14082 - 2.1.1.247 0.000000000000000000000000000000000000000000000000007431 194.0
CSH1_k127_85499_2 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000002226 148.0
CSH1_k127_866956_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 411.0
CSH1_k127_866956_1 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 402.0
CSH1_k127_866956_2 PFAM Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007163 278.0
CSH1_k127_866956_3 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000002458 134.0
CSH1_k127_866956_4 Predicted membrane protein (DUF2318) - - - 0.00000000000000209 87.0
CSH1_k127_866956_5 META domain - - - 0.00000000000009785 76.0
CSH1_k127_866956_6 - - - - 0.00000002055 60.0
CSH1_k127_866956_7 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.0000004463 52.0
CSH1_k127_868410_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 483.0
CSH1_k127_868410_1 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 387.0
CSH1_k127_868410_2 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000000000000000002859 239.0
CSH1_k127_868410_3 Ribosomal S13/S15 N-terminal domain K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000008656 187.0
CSH1_k127_868410_4 PFAM methyltransferase - - - 0.000000000000000001301 88.0
CSH1_k127_868410_5 NUDIX domain K03574 - 3.6.1.55 0.0000000000005054 79.0
CSH1_k127_868410_6 - - - - 0.000003151 52.0
CSH1_k127_881917_0 Transcriptional regulators - - - 0.0003874 48.0
CSH1_k127_887503_0 Type II/IV secretion system protein K07332 - - 3.243e-219 692.0
CSH1_k127_887503_1 Double zinc ribbon - - - 0.000000000000000000000000000000000004441 158.0
CSH1_k127_887503_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000000000000000001979 111.0
CSH1_k127_928108_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 552.0
CSH1_k127_928108_1 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000000000000000001752 149.0
CSH1_k127_928108_2 Amidohydrolase K07045 - - 0.0000000000000000000000000000009949 132.0
CSH1_k127_928108_3 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000002284 102.0
CSH1_k127_928108_4 Ribosomal protein L37e K02922 - - 0.0000000000000000008615 86.0
CSH1_k127_928108_5 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.00000000000000001655 86.0
CSH1_k127_940183_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 582.0
CSH1_k127_940183_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 573.0
CSH1_k127_940183_2 Uroporphyrinogen decarboxylase K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 414.0
CSH1_k127_940183_3 - - - - 0.000004933 49.0
CSH1_k127_941373_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 326.0
CSH1_k127_941373_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 288.0
CSH1_k127_941373_2 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000000002652 223.0
CSH1_k127_941373_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000002599 207.0
CSH1_k127_941373_4 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000001374 207.0
CSH1_k127_941373_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000003875 183.0
CSH1_k127_968742_0 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 334.0
CSH1_k127_968742_1 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000001044 129.0