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Overview

ID MAG00602
Name CSH2_bin.1
Sample SMP0014
Taxonomy
Kingdom Bacteria
Phylum Spirochaetota
Class UBA4802
Order UBA4802
Family JAFGDQ01
Genus JAFGSG01
Species
Assembly information
Completeness (%) 80.88
Contamination (%) 2.17
GC content (%) 37.0
N50 (bp) 4,016
Genome size (bp) 2,385,774

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2114

Gene name Description KEGG GOs EC E-value Score Sequence
CSH2_k127_1000255_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 526.0
CSH2_k127_1000255_1 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 505.0
CSH2_k127_1000255_2 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000003465 235.0
CSH2_k127_1000255_3 - - - - 0.00000000000000000000000000000000000000000000000003645 187.0
CSH2_k127_1000255_4 transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000004317 172.0
CSH2_k127_1000255_5 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000227 170.0
CSH2_k127_1000255_6 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000003745 110.0
CSH2_k127_1000255_7 FecR protein - - - 0.00000008877 64.0
CSH2_k127_100178_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 579.0
CSH2_k127_100178_1 CheR methyltransferase, SAM binding domain K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000009445 260.0
CSH2_k127_100178_2 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000746 142.0
CSH2_k127_100178_3 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000005322 141.0
CSH2_k127_100178_4 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000001475 130.0
CSH2_k127_1029340_0 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000002672 198.0
CSH2_k127_1029340_1 Uncharacterised protein family (UPF0093) - - - 0.0000000000000000000001958 98.0
CSH2_k127_1029340_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000002126 73.0
CSH2_k127_1029340_3 Iron-sulfur cluster-binding domain - - - 0.000000002205 69.0
CSH2_k127_1029340_4 FecR protein - - - 0.00004505 55.0
CSH2_k127_1029508_0 Aerotolerance regulator N-terminal - - - 0.000004876 59.0
CSH2_k127_1059265_0 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 565.0
CSH2_k127_1059265_1 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 343.0
CSH2_k127_1059265_2 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000003593 231.0
CSH2_k127_1059265_3 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000004757 179.0
CSH2_k127_1059265_4 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000000006912 102.0
CSH2_k127_1059265_6 positive regulation of type IV pilus biogenesis K07343 - - 0.000000000002446 67.0
CSH2_k127_1059265_7 FecR protein - - - 0.000000000595 68.0
CSH2_k127_1072683_0 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 267.0
CSH2_k127_1072683_1 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000004396 159.0
CSH2_k127_1072683_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000005553 152.0
CSH2_k127_1072683_3 iron-sulfur transferase activity K07126,K13819 - - 0.000000000002582 71.0
CSH2_k127_1078537_0 PolyA polymerase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 467.0
CSH2_k127_110804_0 protein histidine kinase activity K07679,K10439 - 2.7.13.3 0.0000000000000000000000000000000000002418 155.0
CSH2_k127_110804_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000003021 59.0
CSH2_k127_1126277_0 PFAM aminotransferase, class I K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 492.0
CSH2_k127_1126277_1 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 372.0
CSH2_k127_1126277_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 299.0
CSH2_k127_1126277_3 Diguanylate cyclase K20971 - - 0.00000000000000000000000000000000000000000000000000000000000465 228.0
CSH2_k127_1126277_4 methyltransferase activity - - - 0.000000000000000000000000004404 118.0
CSH2_k127_1126277_5 PFAM Methyltransferase type - - - 0.0000000000000000000001694 108.0
CSH2_k127_1144272_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 362.0
CSH2_k127_1144272_1 SMART Metal-dependent phosphohydrolase, HD region K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 353.0
CSH2_k127_1144272_2 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 312.0
CSH2_k127_1144272_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000002482 55.0
CSH2_k127_115218_0 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 291.0
CSH2_k127_115218_1 Putative Fe-S cluster - - - 0.0000000003651 68.0
CSH2_k127_115218_2 Protein of unknown function (DUF1573) - - - 0.00001734 49.0
CSH2_k127_115218_3 Protein of unknown function (DUF1573) - - - 0.0003521 45.0
CSH2_k127_1161578_0 PFAM Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 2.72e-303 941.0
CSH2_k127_1161578_1 TIGRFAM glutamate synthases, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.000002897 49.0
CSH2_k127_1173269_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 281.0
CSH2_k127_1173269_1 Heptosyltransferase II K02843 - - 0.000000005438 59.0
CSH2_k127_1177594_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 344.0
CSH2_k127_1177594_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000005563 166.0
CSH2_k127_1177594_2 DNA polymerase Ligase (LigD) - - - 0.00000000000001733 78.0
CSH2_k127_1178546_0 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003862 282.0
CSH2_k127_1178546_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000001633 134.0
CSH2_k127_1178546_2 cAMP biosynthetic process - - - 0.000003367 58.0
CSH2_k127_1180073_0 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000001437 199.0
CSH2_k127_1180073_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000281 190.0
CSH2_k127_1180073_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000001604 162.0
CSH2_k127_1180073_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000001449 141.0
CSH2_k127_1180073_4 ThiS family K03154 - - 0.000000001551 61.0
CSH2_k127_1180073_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000001474 61.0
CSH2_k127_118825_0 Alpha-2-Macroglobulin K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 339.0
CSH2_k127_1190038_0 ABC transporter K02003,K05685 - - 5.811e-218 694.0
CSH2_k127_1190038_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 351.0
CSH2_k127_1190038_2 TIGRFAM efflux transporter, RND family, MFP subunit K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003667 285.0
CSH2_k127_1190038_3 PFAM outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003844 259.0
CSH2_k127_1207463_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 529.0
CSH2_k127_1207463_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 376.0
CSH2_k127_1207463_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 328.0
CSH2_k127_1207463_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000003036 215.0
CSH2_k127_1207463_4 PFAM Ribose galactose isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000003482 179.0
CSH2_k127_1211491_0 - - - - 0.0000000000000000000000000000000000007985 146.0
CSH2_k127_1211491_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000001316 95.0
CSH2_k127_1211491_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000003825 90.0
CSH2_k127_1211491_3 ThiS family - - - 0.0000000000000002225 80.0
CSH2_k127_1229301_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 321.0
CSH2_k127_1251779_0 Mur ligase middle domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000001624 258.0
CSH2_k127_1251779_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000002437 238.0
CSH2_k127_1251779_2 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000003594 181.0
CSH2_k127_1251779_3 ADP-ribosylglycohydrolase - - - 0.0000000000000001813 92.0
CSH2_k127_1257257_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 331.0
CSH2_k127_1257257_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000002034 196.0
CSH2_k127_1257257_2 Belongs to the SEDS family K03588 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000009795 136.0
CSH2_k127_1258726_0 ATP cone domain K21636 - 1.1.98.6 5.526e-299 930.0
CSH2_k127_1258726_1 BadF BadG BcrA BcrD - - - 3.697e-297 959.0
CSH2_k127_1258726_2 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro K02566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001453 286.0
CSH2_k127_1258726_3 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000006313 203.0
CSH2_k127_1258726_4 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000000000000000000000000006144 147.0
CSH2_k127_1258726_5 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000000001388 79.0
CSH2_k127_1258726_6 Anaerobic ribonucleoside-triphosphate reductase - - - 0.0000000000209 65.0
CSH2_k127_1258846_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.784e-195 617.0
CSH2_k127_1258846_1 overlaps another CDS with the same product name - - - 0.0000000000000000001167 98.0
CSH2_k127_1258846_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000002341 59.0
CSH2_k127_1259067_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 345.0
CSH2_k127_1259067_1 PFAM Borrelia P83 100 protein - - - 0.0000000000000000000000000000000000000000000000000001075 207.0
CSH2_k127_1259067_2 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000006254 94.0
CSH2_k127_1259067_3 Nucleotidyl transferase - - - 0.0000000000000004874 87.0
CSH2_k127_1259067_4 Smr domain - - - 0.000000001364 62.0
CSH2_k127_1268099_0 Belongs to the sigma-70 factor family K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 342.0
CSH2_k127_1268099_1 COGs COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain K09749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 339.0
CSH2_k127_1268099_2 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 299.0
CSH2_k127_1268099_3 flagellar biosynthesis protein FlhF K02404 - - 0.000000000000000000000000000000000000000000000001763 185.0
CSH2_k127_1271669_0 Cache domain - - - 8.864e-225 711.0
CSH2_k127_1271669_1 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 601.0
CSH2_k127_1271669_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 349.0
CSH2_k127_1271669_3 response regulator, receiver K07814 - - 0.0000000000000000000001517 99.0
CSH2_k127_1286950_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.694e-198 631.0
CSH2_k127_1286950_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 415.0
CSH2_k127_1309870_0 von Willebrand factor, type A K07114 - - 2.03e-225 721.0
CSH2_k127_1309870_1 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 376.0
CSH2_k127_1309870_2 COG2755 Lysophospholipase L1 and related K10804 - 3.1.1.5 0.0000000000000009171 85.0
CSH2_k127_1311511_0 PFAM FecR protein K01387 - 3.4.24.3 0.000000006444 66.0
CSH2_k127_1311511_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000121 64.0
CSH2_k127_1313285_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 1.369e-238 767.0
CSH2_k127_1314596_0 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 1.373e-240 754.0
CSH2_k127_1314596_1 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000005533 64.0
CSH2_k127_1327203_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00002432 57.0
CSH2_k127_1329475_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 581.0
CSH2_k127_1330592_0 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000006647 229.0
CSH2_k127_1330592_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000003047 147.0
CSH2_k127_1330592_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000003646 135.0
CSH2_k127_1333825_0 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000003422 175.0
CSH2_k127_1333825_1 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000004814 85.0
CSH2_k127_1333825_2 Preprotein translocase SecG subunit K03075 - - 0.0000005674 56.0
CSH2_k127_1333825_3 TonB-dependent Receptor Plug Domain K16092 - - 0.0001385 54.0
CSH2_k127_1340444_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.758e-289 902.0
CSH2_k127_1340524_0 Belongs to the bacterial solute-binding protein 9 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 375.0
CSH2_k127_1340524_1 Large extracellular alpha-helical protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 387.0
CSH2_k127_1341578_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 344.0
CSH2_k127_1341578_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000006871 195.0
CSH2_k127_1346252_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002963 253.0
CSH2_k127_1346252_1 - - - - 0.00000000000000000000000000000003737 141.0
CSH2_k127_1346252_2 - - - - 0.00000000000005462 73.0
CSH2_k127_1346252_3 PFAM SMP-30 Gluconolaconase - - - 0.000001311 61.0
CSH2_k127_134691_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.373e-214 672.0
CSH2_k127_134691_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 526.0
CSH2_k127_1347108_0 flagellar motor switch protein K02417 - - 0.00000000000000000000000000000000000000000000000000000000000000000009567 244.0
CSH2_k127_1347108_1 protein, possibly involved in motility K02385 - - 0.0000000000007571 71.0
CSH2_k127_1347108_2 Protein of unknown function DUF115 - - - 0.00000000006969 72.0
CSH2_k127_1347108_3 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.0001912 50.0
CSH2_k127_1350670_0 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001788 271.0
CSH2_k127_1350670_1 Belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000000000000000000008008 154.0
CSH2_k127_1350670_2 - - - - 0.00000000001651 66.0
CSH2_k127_135127_0 PFAM response regulator receiver K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000954 246.0
CSH2_k127_135127_1 Domain of unknown function (DUF4405) - - - 0.0001283 47.0
CSH2_k127_135127_2 histidine kinase HAMP region domain protein K07640 - 2.7.13.3 0.0002045 50.0
CSH2_k127_1352638_0 amino acid transport K02030 - - 0.000000000000000000000000000000000000000000000004323 181.0
CSH2_k127_1352638_1 amino acid transport K02030 - - 0.00000000000000000000000000000000000000000002768 170.0
CSH2_k127_1352638_2 ATP-binding region ATPase domain protein, response regulator receiver, histidine kinase A domain protein - - - 0.0002749 50.0
CSH2_k127_1354276_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 529.0
CSH2_k127_1354708_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 7.406e-289 907.0
CSH2_k127_1354708_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 515.0
CSH2_k127_1354708_2 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 322.0
CSH2_k127_1354708_3 PFAM Capsule synthesis protein, CapA K07282 - - 0.00000000000000000000000000000000000000000000000000000000002662 218.0
CSH2_k127_1354708_4 TIGRFAM tRNA 2-selenouridine synthase K06917 - - 0.00000000000000000000000000000000000000000001126 177.0
CSH2_k127_1354708_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000003225 67.0
CSH2_k127_1367220_0 all-trans-retinol 13,14-reductase activity K01854,K09845,K10027 - 1.3.99.26,1.3.99.27,1.3.99.28,1.3.99.29,1.3.99.31,5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 311.0
CSH2_k127_1367220_1 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 307.0
CSH2_k127_1367220_2 Belongs to the FPP GGPP synthase family K00805,K02523,K13787,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000001392 245.0
CSH2_k127_1367220_3 Flavin containing amine oxidoreductase K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.0000000000000000000000000000000000000000467 154.0
CSH2_k127_1376591_0 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 411.0
CSH2_k127_1376591_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 321.0
CSH2_k127_1376591_2 RNA recognition motif - - - 0.0000000000000000000000000000001199 127.0
CSH2_k127_1376591_4 Protein of unknown function (DUF2892) - - - 0.00000000000000001105 84.0
CSH2_k127_1376591_5 oxidoreductase activity - - - 0.0000000007141 68.0
CSH2_k127_1376591_6 Domain of unknown function (DUF4340) - - - 0.000000003463 68.0
CSH2_k127_1390504_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 356.0
CSH2_k127_1390504_1 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000009839 127.0
CSH2_k127_142749_0 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 348.0
CSH2_k127_142749_1 PFAM Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000008478 102.0
CSH2_k127_1429657_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 554.0
CSH2_k127_1429657_1 protein methyltransferase activity K11434,K15984,K20421 - 2.1.1.242,2.1.1.303,2.1.1.319 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 289.0
CSH2_k127_1429686_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000001275 241.0
CSH2_k127_1429686_1 - - - - 0.000000000000000000000000001232 117.0
CSH2_k127_1429686_2 Protein of unknown function (DUF2905) - - - 0.000000000000000556 81.0
CSH2_k127_1444855_0 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003022 241.0
CSH2_k127_1444855_1 Peptidase, M23 - - - 0.0000000000000000000000000000000000000000000002199 180.0
CSH2_k127_1471403_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 3.692e-206 654.0
CSH2_k127_1471403_1 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 391.0
CSH2_k127_1471403_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000002169 254.0
CSH2_k127_147733_0 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002853 281.0
CSH2_k127_147733_1 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000008052 136.0
CSH2_k127_147733_2 Flagellar biosynthetic protein FliQ K02420 - - 0.000000000000000000002766 96.0
CSH2_k127_1504260_0 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004756 285.0
CSH2_k127_1504260_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001971 255.0
CSH2_k127_1504260_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000005853 197.0
CSH2_k127_1504260_3 HAD-hyrolase-like K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.00000000000000000000000000000000000000001202 161.0
CSH2_k127_1504260_4 - - - - 0.0000000005207 62.0
CSH2_k127_1504260_5 PFAM Tetratricopeptide repeat - - - 0.000001531 59.0
CSH2_k127_1521839_0 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 499.0
CSH2_k127_1521839_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347,K03614 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 374.0
CSH2_k127_1521839_2 Fe-S cluster K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 329.0
CSH2_k127_1521839_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 320.0
CSH2_k127_1521839_4 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 288.0
CSH2_k127_1521839_5 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 284.0
CSH2_k127_1521839_6 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000000111 223.0
CSH2_k127_1521839_7 TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000001671 168.0
CSH2_k127_1521839_8 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000002951 79.0
CSH2_k127_1522708_0 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 485.0
CSH2_k127_1522708_1 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain K02030 - - 0.0000000000000000000000000004134 123.0
CSH2_k127_152808_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K18331 - 1.12.1.3 3.585e-319 1009.0
CSH2_k127_152808_1 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000924 276.0
CSH2_k127_152808_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000001776 186.0
CSH2_k127_152808_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K17999 - 1.12.1.4,1.6.5.3 0.00000000000000000000000000000000000000000000000414 176.0
CSH2_k127_152808_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000006439 170.0
CSH2_k127_152808_5 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000002435 159.0
CSH2_k127_152808_6 Tetratricopeptide repeat - - - 0.0007996 51.0
CSH2_k127_1530011_0 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000003073 222.0
CSH2_k127_1530011_1 PFAM PHP domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.00000000000000000000000000000000000000000003564 166.0
CSH2_k127_1530011_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000002722 62.0
CSH2_k127_1537266_0 chelatase, subunit chli K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 509.0
CSH2_k127_154395_0 Belongs to the 5'-nucleotidase family K08693,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000003348 60.0
CSH2_k127_1554487_0 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 434.0
CSH2_k127_1554487_1 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 313.0
CSH2_k127_1554487_2 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005227 256.0
CSH2_k127_1554487_3 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000004888 151.0
CSH2_k127_1554487_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000001343 119.0
CSH2_k127_1554487_5 TIGRFAM phosphodiesterase, MJ0936 family K07095 - - 0.0000000000000000000006507 101.0
CSH2_k127_1554487_6 S-layer homology domain - - - 0.0000000002131 72.0
CSH2_k127_1563106_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 368.0
CSH2_k127_1563106_1 SCO1/SenC - - - 0.00000000000000000000000000000000000000000000002757 173.0
CSH2_k127_1587958_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 5.749e-242 767.0
CSH2_k127_1587958_1 - - - - 0.0000000000000000000000000000000000000000000000000209 186.0
CSH2_k127_1639465_0 Ketoacyl-synthetase C-terminal extension - - - 7.491e-293 939.0
CSH2_k127_1640498_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 506.0
CSH2_k127_1640498_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000006172 194.0
CSH2_k127_1655470_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K12142,K15830 GO:0003674,GO:0005488,GO:0016151,GO:0043167,GO:0043169,GO:0046872,GO:0046914 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 478.0
CSH2_k127_1655470_1 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 346.0
CSH2_k127_1709380_0 C-terminal, D2-small domain, of ClpB protein K03694 - - 1.13e-229 720.0
CSH2_k127_1709380_1 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000001045 181.0
CSH2_k127_1712021_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 413.0
CSH2_k127_1712021_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 310.0
CSH2_k127_1733956_0 Pfam:UPF0118 - - - 0.0000000000000000000001999 109.0
CSH2_k127_1733956_1 cellulase activity K20276 - - 0.00003581 56.0
CSH2_k127_1738632_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 354.0
CSH2_k127_1738632_1 translation elongation factor K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 345.0
CSH2_k127_1738632_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000002683 179.0
CSH2_k127_1738632_3 SMART Metal-dependent phosphohydrolase, HD region - - - 0.00000000000000000000000000000000000006762 154.0
CSH2_k127_1769043_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 498.0
CSH2_k127_1769043_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 315.0
CSH2_k127_1769043_2 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003941 251.0
CSH2_k127_1769043_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000354 204.0
CSH2_k127_1785109_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000001066 75.0
CSH2_k127_181085_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.522e-231 722.0
CSH2_k127_181085_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 443.0
CSH2_k127_181085_2 trp operon repressor K03720 - - 0.00000000000000000002365 94.0
CSH2_k127_1852578_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 5.979e-252 798.0
CSH2_k127_1852578_1 Aminotransferase class-III K01845,K07257,K21585 - 2.6.1.111,5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 424.0
CSH2_k127_1852578_2 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000001228 188.0
CSH2_k127_186313_0 GGDEF domain - - - 0.0000000000000000000000000000000000000000009414 164.0
CSH2_k127_1866218_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 413.0
CSH2_k127_1866218_1 Peptidase, M23 family - - - 0.00000000000000000000000000000000000000002414 165.0
CSH2_k127_1866218_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000001096 136.0
CSH2_k127_1866218_3 Mammalian cell entry related domain protein K02067 - - 0.000000000000000000008449 103.0
CSH2_k127_1868064_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 432.0
CSH2_k127_1868064_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 311.0
CSH2_k127_1868064_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000008185 225.0
CSH2_k127_1868064_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000006665 143.0
CSH2_k127_1881304_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000005328 117.0
CSH2_k127_1881304_1 PFAM Type II secretion system protein E K02652 - - 0.00002366 50.0
CSH2_k127_190364_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 321.0
CSH2_k127_190364_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000007684 194.0
CSH2_k127_190364_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000001156 161.0
CSH2_k127_190364_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000003452 160.0
CSH2_k127_190364_4 Response regulator receiver K03413 - - 0.000000000000000000000000000000000000002665 151.0
CSH2_k127_1919826_0 transferase activity, transferring glycosyl groups K13693,K21349 - 2.4.1.266,2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 481.0
CSH2_k127_1919826_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009808 258.0
CSH2_k127_1919826_2 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0000000000000000000000000000000000000000000000000004171 186.0
CSH2_k127_1919826_3 PFAM Curli production assembly transport component CsgG - - - 0.000000003733 67.0
CSH2_k127_1919826_4 - - - - 0.000009879 56.0
CSH2_k127_1938361_0 Nucleoside recognition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005692 254.0
CSH2_k127_1938361_1 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000002151 86.0
CSH2_k127_1949923_0 TIGRFAM NRAMP (natural resistance-associated macrophage protein) metal ion transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 589.0
CSH2_k127_1949923_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 566.0
CSH2_k127_1949923_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 511.0
CSH2_k127_1949923_3 MgtE intracellular N domain K02000,K05847 - 3.6.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000005252 271.0
CSH2_k127_1949923_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002375 258.0
CSH2_k127_1949923_5 - - - - 0.00000000000000000000000000000000000000000004966 162.0
CSH2_k127_1949923_6 carbon starvation protein CstA K06200 - - 0.00000002203 57.0
CSH2_k127_197226_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 585.0
CSH2_k127_197226_1 PFAM Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 426.0
CSH2_k127_197226_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 367.0
CSH2_k127_1992516_0 Peptidase family U32 C-terminal domain K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 295.0
CSH2_k127_1992516_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001443 263.0
CSH2_k127_1992516_2 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000565 205.0
CSH2_k127_1999379_0 Bacterial protein of unknown function (DUF898) - - - 0.0000000000000000000000000000000000000000000000000000000000005224 222.0
CSH2_k127_1999379_1 chaperone-mediated protein folding - - - 0.00000000000000000000000000000003002 139.0
CSH2_k127_2009440_0 CHASE - - - 0.000000000000000000000000000000000000000000000000000000002021 219.0
CSH2_k127_2009440_1 Cache_2 - - - 0.0000000000000000000000000000000000000000005866 175.0
CSH2_k127_2009440_2 Rubrerythrin - - - 0.000000000000000000000000000000000000004344 153.0
CSH2_k127_2009440_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000616 68.0
CSH2_k127_2014493_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 298.0
CSH2_k127_2014493_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000003962 203.0
CSH2_k127_2014493_2 HNH endonuclease - - - 0.000000000000000000000000000006561 126.0
CSH2_k127_2014493_3 Domain of unknown function (DUF4398) - - - 0.000000003122 69.0
CSH2_k127_2018239_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 5.898e-286 891.0
CSH2_k127_2018239_1 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000009489 189.0
CSH2_k127_203687_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000002667 260.0
CSH2_k127_203687_1 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000003297 231.0
CSH2_k127_203687_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K03624,K06140 - - 0.000000000000000008566 88.0
CSH2_k127_203687_3 PFAM OmpA MotB domain protein K02557 - - 0.00001248 47.0
CSH2_k127_204801_0 phosphoglucosamine mutase activity K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 314.0
CSH2_k127_204801_1 Short C-terminal domain K08982 - - 0.00000001996 60.0
CSH2_k127_2063934_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 392.0
CSH2_k127_2063934_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000005058 230.0
CSH2_k127_2063934_2 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000357 162.0
CSH2_k127_2063934_3 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - 0.0000000000000000000001162 103.0
CSH2_k127_2063934_4 Belongs to the UPF0235 family K09131 - - 0.00000000005126 66.0
CSH2_k127_2063934_5 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) K04749 - - 0.00000509 53.0
CSH2_k127_2076969_0 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 1.926e-203 646.0
CSH2_k127_2076969_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000009388 263.0
CSH2_k127_2076969_2 Carboxypeptidase K21464 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001417 267.0
CSH2_k127_2133849_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 477.0
CSH2_k127_2133849_1 PFAM Radical SAM K22226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 454.0
CSH2_k127_2133849_2 CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 378.0
CSH2_k127_2133849_3 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000003092 159.0
CSH2_k127_2133849_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000001972 108.0
CSH2_k127_2140098_0 Outer membrane protein beta-barrel family K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001831 285.0
CSH2_k127_2140098_1 Outer membrane protein beta-barrel family K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000227 286.0
CSH2_k127_2150578_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 466.0
CSH2_k127_2150578_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000005607 154.0
CSH2_k127_2150578_2 superoxide reductase activity K05919 - 1.15.1.2 0.00000000000000000000009731 102.0
CSH2_k127_2150578_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000003488 55.0
CSH2_k127_2159114_0 Radical_SAM C-terminal domain K07139 - - 0.000000000000000000000000000000000000000002137 161.0
CSH2_k127_2170716_0 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000001195 91.0
CSH2_k127_2182309_0 PFAM Pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 582.0
CSH2_k127_2183762_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.068e-248 784.0
CSH2_k127_2183762_1 quinolinate catabolic process K00278,K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003669 278.0
CSH2_k127_2183762_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000168 153.0
CSH2_k127_2183762_3 Universal bacterial protein YeaZ K01409,K14742 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000006394 100.0
CSH2_k127_2183868_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 335.0
CSH2_k127_2183868_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000001328 208.0
CSH2_k127_2183868_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000006933 77.0
CSH2_k127_2203539_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.00000000000000000000000000000000000000000000000000000003903 199.0
CSH2_k127_2203539_1 - - - - 0.00000000000000000000008184 103.0
CSH2_k127_2237529_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000007038 110.0
CSH2_k127_2237529_1 ParB domain protein nuclease K03497 - - 0.0004487 49.0
CSH2_k127_2240717_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.487e-237 740.0
CSH2_k127_2240717_1 PFAM Acetyl-CoA hydrolase transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 348.0
CSH2_k127_2240717_2 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000299 286.0
CSH2_k127_2240717_3 regulation of ryanodine-sensitive calcium-release channel activity K07273 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001825 268.0
CSH2_k127_2240717_4 Protein of unknown function DUF115 - - - 0.0000000000000000000000000000000000000000000000000000001396 215.0
CSH2_k127_2240717_5 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000005048 143.0
CSH2_k127_2240717_6 - - - - 0.000000000008642 75.0
CSH2_k127_2266772_0 Phosphate-selective porin O and P - - - 0.0000000000000000000000000005086 124.0
CSH2_k127_2266772_1 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.0000000000002052 84.0
CSH2_k127_2270049_0 BFD-like [2Fe-2S] binding domain K00111 - 1.1.5.3 4.527e-216 683.0
CSH2_k127_2270049_1 response to heat K07090 - - 0.0000000000000000000000002068 115.0
CSH2_k127_2270049_2 Thioredoxin - - - 0.000000000004805 78.0
CSH2_k127_2270049_3 phosphorelay sensor kinase activity K03406 - - 0.0000000129 65.0
CSH2_k127_2270049_4 Anaerobic glycerol-3-phosphate dehydrogenase, subunit K00112 - 1.1.5.3 0.000009069 47.0
CSH2_k127_2276781_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.982e-205 652.0
CSH2_k127_2276781_1 regulation of ryanodine-sensitive calcium-release channel activity - - - 0.00000000000000000000000000000000000000000000000004552 188.0
CSH2_k127_2281638_0 Bacterial DNA polymerase III alpha subunit K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 2.429e-202 654.0
CSH2_k127_2281638_1 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 451.0
CSH2_k127_2281638_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 349.0
CSH2_k127_2281638_3 Belongs to the UPF0336 family - - - 0.000006082 55.0
CSH2_k127_2283031_0 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 437.0
CSH2_k127_2283031_1 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 359.0
CSH2_k127_2283031_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000774 148.0
CSH2_k127_2283031_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000006466 117.0
CSH2_k127_2283031_4 Astacin (Peptidase family M12A) K08076 GO:0007275,GO:0007610,GO:0007631,GO:0008150,GO:0032501,GO:0032502,GO:0035295,GO:0042755,GO:0043050,GO:0048565,GO:0048731,GO:0048856,GO:0055123,GO:0060465 3.4.24.21 0.000000000000000000000004043 109.0
CSH2_k127_2283031_5 Histidine kinase - - - 0.00000000001493 72.0
CSH2_k127_2283031_6 Cytochrome c554 and c-prime - - - 0.00000001875 61.0
CSH2_k127_2283031_7 - - - - 0.000001232 50.0
CSH2_k127_2287411_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000001375 221.0
CSH2_k127_2287490_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 513.0
CSH2_k127_2287490_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 444.0
CSH2_k127_2287490_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 321.0
CSH2_k127_2287490_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503,K19710,K21220 - 2.5.1.3,2.7.7.53 0.00000000000000000000002516 104.0
CSH2_k127_2298099_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000006426 97.0
CSH2_k127_230021_0 - - - - 0.000000000000000000000000000000000000000000000001241 198.0
CSH2_k127_2301599_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 494.0
CSH2_k127_2301599_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 286.0
CSH2_k127_2345578_0 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 422.0
CSH2_k127_2345578_1 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 363.0
CSH2_k127_2345578_2 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001346 242.0
CSH2_k127_2345578_3 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 - 0.00003017 46.0
CSH2_k127_2355641_0 Protein tyrosine phosphatase, receptor type Q K05694,K16910 GO:0008150,GO:0045595,GO:0045598,GO:0050789,GO:0050793,GO:0050794,GO:0065007 3.1.3.48 0.0000000004822 69.0
CSH2_k127_2355641_1 FecR protein - - - 0.0000001342 63.0
CSH2_k127_2373507_0 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000003257 200.0
CSH2_k127_2373507_1 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.0000000000000000000000000000000000000002896 158.0
CSH2_k127_2373507_2 ATPase activity K01990,K02193 - 3.6.3.41 0.00000000000000000000000000000000002521 143.0
CSH2_k127_2373507_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0004623 46.0
CSH2_k127_2375526_0 DNA photolyase activity K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000000000000000004484 242.0
CSH2_k127_2375526_1 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0000000000000000000000000000000000000000000000000000000005816 210.0
CSH2_k127_2375526_2 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000002542 62.0
CSH2_k127_2383641_0 PFAM VanW family protein K18346 - - 0.000000000000000000000000000000002942 135.0
CSH2_k127_2383641_1 cell wall anchor domain - - - 0.000000002546 70.0
CSH2_k127_2383641_2 AMMECR1 K06990,K09141 - - 0.00000007907 61.0
CSH2_k127_2384584_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000001963 197.0
CSH2_k127_2384584_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000001057 66.0
CSH2_k127_2384584_3 NLI interacting factor-like phosphatase family protein K15731 - 3.1.3.16 0.000001176 56.0
CSH2_k127_2394020_0 glycerone kinase activity K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 464.0
CSH2_k127_2394020_1 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 358.0
CSH2_k127_2394020_2 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000001049 157.0
CSH2_k127_2422920_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 443.0
CSH2_k127_2422920_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000001174 220.0
CSH2_k127_2422920_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000008197 124.0
CSH2_k127_2422920_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000005761 87.0
CSH2_k127_2422920_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000001488 56.0
CSH2_k127_2441739_0 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 562.0
CSH2_k127_2441739_1 metal-dependent phosphohydrolase HD region K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 428.0
CSH2_k127_2441739_2 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000002229 218.0
CSH2_k127_2443272_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6.035e-200 630.0
CSH2_k127_2443272_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 575.0
CSH2_k127_2443272_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 446.0
CSH2_k127_2443272_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 348.0
CSH2_k127_2443272_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000003497 139.0
CSH2_k127_2443272_5 Competence protein K02238 - - 0.000000000000000000000000000003263 138.0
CSH2_k127_2443272_6 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000172 60.0
CSH2_k127_2443272_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0032940,GO:0033036,GO:0034613,GO:0042597,GO:0042886,GO:0042953,GO:0042954,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051641,GO:0070727,GO:0071702,GO:0071705,GO:0072321,GO:0072322,GO:0072323,GO:0072657 - 0.00004157 53.0
CSH2_k127_2451924_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 310.0
CSH2_k127_2451924_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005545 289.0
CSH2_k127_2460260_0 Heat shock 70 kDa protein K04043 - - 2.882e-277 865.0
CSH2_k127_2460260_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 378.0
CSH2_k127_2460260_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000098 53.0
CSH2_k127_2460260_3 PFAM Uncharacterised conserved protein UCP016719 - - - 0.0009181 45.0
CSH2_k127_2462543_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 3.848e-235 742.0
CSH2_k127_2462543_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000305 236.0
CSH2_k127_2472902_0 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000008649 244.0
CSH2_k127_2472902_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000002831 101.0
CSH2_k127_2472902_2 - - - - 0.0000001789 52.0
CSH2_k127_2508176_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 295.0
CSH2_k127_251689_0 cephalosporin-C deacetylase activity K01060 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005975,GO:0005976,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009308,GO:0009987,GO:0010383,GO:0010410,GO:0016787,GO:0016788,GO:0016999,GO:0017144,GO:0019213,GO:0019752,GO:0030653,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043645,GO:0044036,GO:0044106,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0045491,GO:0046483,GO:0046555,GO:0046872,GO:0047739,GO:0052689,GO:0071554,GO:0071704,GO:0072338,GO:1901266,GO:1901360,GO:1901564 3.1.1.41 0.00000000000000000000000000000008879 136.0
CSH2_k127_2538415_0 conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 365.0
CSH2_k127_2538415_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004391 278.0
CSH2_k127_2538415_3 esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.0009632 52.0
CSH2_k127_2559929_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000001779 149.0
CSH2_k127_2559929_1 - - - - 0.0001711 53.0
CSH2_k127_2568377_0 MMPL family K07003 - - 1.196e-220 716.0
CSH2_k127_2587742_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 466.0
CSH2_k127_2587742_1 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003612 265.0
CSH2_k127_2587742_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0000000000000000000000007518 105.0
CSH2_k127_2587742_3 rRNA methyltransferase activity K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000009824 113.0
CSH2_k127_2594256_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.731e-231 727.0
CSH2_k127_2594256_1 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 464.0
CSH2_k127_2594256_2 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 451.0
CSH2_k127_2594256_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 376.0
CSH2_k127_2594256_4 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 371.0
CSH2_k127_2594256_5 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 355.0
CSH2_k127_2594256_6 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 349.0
CSH2_k127_2594256_7 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000006612 187.0
CSH2_k127_2594256_8 ompA family - - - 0.000000000000000000000000000000000000000004022 174.0
CSH2_k127_2594421_0 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000001498 103.0
CSH2_k127_2607821_0 DNA helicase K03657 - 3.6.4.12 2.712e-280 895.0
CSH2_k127_2608452_0 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 509.0
CSH2_k127_2608452_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 517.0
CSH2_k127_2608452_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 326.0
CSH2_k127_2611383_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 398.0
CSH2_k127_2611383_1 Adenylate guanylate cyclase catalytic domain protein K01768 - 4.6.1.1 0.00000000000345 75.0
CSH2_k127_2619243_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 2.597e-243 788.0
CSH2_k127_2619243_1 Outer membrane efflux protein - - - 0.0003316 52.0
CSH2_k127_2620110_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 306.0
CSH2_k127_2620110_1 Uncharacterized ACR, COG1430 - - - 0.0000000000000000000002115 103.0
CSH2_k127_2620110_2 - - - - 0.0003582 51.0
CSH2_k127_2621257_0 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 549.0
CSH2_k127_2621257_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 537.0
CSH2_k127_2621257_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004381 267.0
CSH2_k127_2621257_3 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 0.0000000000000000000008007 100.0
CSH2_k127_2626991_0 AMP-binding enzyme C-terminal domain - - - 3.756e-292 901.0
CSH2_k127_2626991_1 FdhD/NarQ family K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 392.0
CSH2_k127_2626991_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 341.0
CSH2_k127_2626991_3 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000259 114.0
CSH2_k127_2629165_0 Elongator protein 3, MiaB family, Radical SAM - - - 1.144e-209 658.0
CSH2_k127_2629165_2 - - - - 0.000000003088 64.0
CSH2_k127_2629165_3 lipid A biosynthesis acyltransferase - - - 0.00000002364 56.0
CSH2_k127_2639590_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.584e-236 742.0
CSH2_k127_2639590_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 335.0
CSH2_k127_2639590_2 Chaperonin 10 Kd subunit K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000004973 132.0
CSH2_k127_2639590_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000002212 130.0
CSH2_k127_2642966_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 475.0
CSH2_k127_2642966_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 294.0
CSH2_k127_2642966_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000001518 121.0
CSH2_k127_2642966_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000001045 121.0
CSH2_k127_2642966_12 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001832 100.0
CSH2_k127_2642966_13 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000003488 68.0
CSH2_k127_2642966_14 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000001826 65.0
CSH2_k127_2642966_2 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000006279 203.0
CSH2_k127_2642966_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000001705 192.0
CSH2_k127_2642966_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000007339 188.0
CSH2_k127_2642966_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000002005 184.0
CSH2_k127_2642966_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000004291 169.0
CSH2_k127_2642966_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000005169 166.0
CSH2_k127_2642966_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000004568 156.0
CSH2_k127_2642966_9 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001698 128.0
CSH2_k127_2656747_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 398.0
CSH2_k127_2656747_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 303.0
CSH2_k127_2656747_2 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000002 213.0
CSH2_k127_2656747_3 - - - - 0.0000000000000000000000000000000000000000000000000000003001 200.0
CSH2_k127_2682932_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000004882 147.0
CSH2_k127_2689776_0 GAF domain K21009 - - 0.00000000007318 72.0
CSH2_k127_2689776_1 S-layer homology domain - - - 0.0005841 51.0
CSH2_k127_2692304_0 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001943 266.0
CSH2_k127_2692304_1 Iron-containing alcohol dehydrogenase K19954 - - 0.00000000000000000000000000000002086 140.0
CSH2_k127_2692304_2 rRNA processing K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.00000000000000000000000001055 113.0
CSH2_k127_2692304_3 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000003806 91.0
CSH2_k127_2692304_4 factor, FlgM K02398 - - 0.0000478 49.0
CSH2_k127_2696683_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009409 260.0
CSH2_k127_2696683_1 Adenylate guanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000001664 209.0
CSH2_k127_2696683_2 - - - - 0.00000000000004017 83.0
CSH2_k127_2700509_0 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 443.0
CSH2_k127_2700509_1 FlgN protein - - - 0.00003064 52.0
CSH2_k127_2700533_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 475.0
CSH2_k127_2700533_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 465.0
CSH2_k127_2700533_2 Protein of unknown function (DUF3617) - - - 0.0000000000000000001011 94.0
CSH2_k127_2700806_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1036.0
CSH2_k127_2700806_1 flagellar basal-body rod protein FlgG K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 385.0
CSH2_k127_2700806_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 315.0
CSH2_k127_2700806_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000003781 246.0
CSH2_k127_2700806_4 PFAM MORN repeat variant - - - 0.00000000000000000000000002008 123.0
CSH2_k127_2700806_5 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0009135 49.0
CSH2_k127_2704862_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000743 233.0
CSH2_k127_2704862_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000002714 63.0
CSH2_k127_2704862_2 Diguanylate cyclase with PAS PAC and GAF - - - 0.0002896 45.0
CSH2_k127_2710129_0 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 403.0
CSH2_k127_2710129_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 392.0
CSH2_k127_2710129_2 ABC transporter (Permease) K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000008784 228.0
CSH2_k127_2710474_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007633 484.0
CSH2_k127_2710474_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 422.0
CSH2_k127_2710474_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000004744 254.0
CSH2_k127_2710474_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000007601 104.0
CSH2_k127_2710474_4 Treponemal membrane protein - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000004139 72.0
CSH2_k127_2721086_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 556.0
CSH2_k127_2721086_1 Adenylate cyclase K05851 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000304 274.0
CSH2_k127_2721086_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000313 225.0
CSH2_k127_2721086_3 COGs COG0680 Ni Fe-hydrogenase maturation factor K03605 - - 0.00000000000000000000000000000000000000007908 156.0
CSH2_k127_2721086_4 Endonuclease containing a URI domain K07461 - - 0.000000000000000002635 89.0
CSH2_k127_2721086_5 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000004655 57.0
CSH2_k127_2721086_6 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00005964 49.0
CSH2_k127_2722007_0 probably responsible for the translocation of the substrate across the membrane K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 342.0
CSH2_k127_2722007_1 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 304.0
CSH2_k127_2722007_2 PFAM extracellular solute-binding protein family 1 K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000002893 237.0
CSH2_k127_2722007_3 PFAM extracellular solute-binding protein family 1 K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000003622 235.0
CSH2_k127_2723953_0 DNA or RNA helicase of superfamily II K10843 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 557.0
CSH2_k127_2723953_1 HD domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 412.0
CSH2_k127_2723953_2 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007465 258.0
CSH2_k127_2740430_0 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000003678 183.0
CSH2_k127_2740430_1 RES - - - 0.0000000000000000000000000000000000002909 145.0
CSH2_k127_2740430_2 Protein of unknown function (DUF2384) - - - 0.0000000000000000000001476 102.0
CSH2_k127_2772932_0 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000002151 250.0
CSH2_k127_2772932_1 Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.00000000000000000000000000000000000000000000001324 184.0
CSH2_k127_2772932_2 Protein of unknown function (DUF4254) - - - 0.00000000000000000000000000000000001907 142.0
CSH2_k127_2772932_3 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 0.00000000000000000000000000005979 117.0
CSH2_k127_2772932_4 FecR protein - - - 0.000000000001683 76.0
CSH2_k127_2772932_5 DNA-binding transcription factor activity K21903 - - 0.000000002387 62.0
CSH2_k127_278827_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1517.0
CSH2_k127_278827_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.0 1163.0
CSH2_k127_278827_2 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 399.0
CSH2_k127_278827_3 4fe-4S ferredoxin, iron-sulfur binding domain protein K19516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 299.0
CSH2_k127_278827_4 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000958 209.0
CSH2_k127_278827_5 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000369 128.0
CSH2_k127_278827_6 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000008884 59.0
CSH2_k127_2792371_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 4.388e-220 691.0
CSH2_k127_2792371_1 Cys Met metabolism pyridoxal-phosphate-dependent protein K01739,K01760 - 2.5.1.48,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 457.0
CSH2_k127_2792371_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 342.0
CSH2_k127_2792371_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 329.0
CSH2_k127_2792371_4 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000002208 144.0
CSH2_k127_2792371_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000006258 92.0
CSH2_k127_2792371_6 Cysteine protease Prp K07584 - - 0.00000000001112 69.0
CSH2_k127_2792371_7 ABC transporter (Permease K15771 - - 0.0005002 48.0
CSH2_k127_279998_0 7TM diverse intracellular signalling - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 424.0
CSH2_k127_2803113_0 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 328.0
CSH2_k127_2803113_1 Enoyl-CoA hydratase/isomerase K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000002006 238.0
CSH2_k127_2803113_2 Belongs to the thiolase family - - - 0.00000000000000000000000000001539 118.0
CSH2_k127_282574_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.964e-234 735.0
CSH2_k127_282574_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000006669 162.0
CSH2_k127_282574_2 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000001937 55.0
CSH2_k127_2830554_0 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 396.0
CSH2_k127_2830554_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000006402 233.0
CSH2_k127_2830554_2 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000002753 211.0
CSH2_k127_2830554_3 N-acetylneuraminate synthase K01654,K18430 - 2.5.1.101,2.5.1.56 0.000000000006395 70.0
CSH2_k127_2830554_4 Type II IV secretion system protein K02454,K02652 - - 0.0000000003749 62.0
CSH2_k127_283556_0 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000405 123.0
CSH2_k127_283556_1 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000002489 71.0
CSH2_k127_2840906_0 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000003971 127.0
CSH2_k127_2840906_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000001328 112.0
CSH2_k127_2840906_2 COG0848 Biopolymer transport protein K03559 - - 0.0000000005228 66.0
CSH2_k127_2840906_3 Outer membrane efflux protein K12538 - - 0.0000009704 61.0
CSH2_k127_2849982_0 Valyl tRNA synthetase tRNA binding arm K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 308.0
CSH2_k127_2853714_0 transglycosylase K08309 - - 0.0000000000000000000000002799 109.0
CSH2_k127_2853714_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000006658 96.0
CSH2_k127_2868961_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 408.0
CSH2_k127_2868961_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 296.0
CSH2_k127_2868961_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000002438 216.0
CSH2_k127_2868961_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000002408 102.0
CSH2_k127_2868961_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000009707 66.0
CSH2_k127_2882593_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 444.0
CSH2_k127_2882593_1 flagellar basal-body rod protein K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 326.0
CSH2_k127_2882593_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000001937 64.0
CSH2_k127_2882799_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000007435 224.0
CSH2_k127_2884650_0 radical SAM domain protein K07739 - 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000409 248.0
CSH2_k127_2884650_1 - - - - 0.000000000000000000000000000000000018 143.0
CSH2_k127_2884650_2 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000004165 109.0
CSH2_k127_2889055_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004025 261.0
CSH2_k127_2889055_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000005967 132.0
CSH2_k127_2889055_2 Belongs to the P-Pant transferase superfamily - - - 0.0001136 52.0
CSH2_k127_2893869_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 380.0
CSH2_k127_2893869_1 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000001095 185.0
CSH2_k127_2922523_0 Proposed homoserine kinase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000001336 187.0
CSH2_k127_2922523_2 flagellar filament outer layer protein - - - 0.000000001717 67.0
CSH2_k127_2923509_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 464.0
CSH2_k127_2923509_1 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 399.0
CSH2_k127_2923509_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001286 242.0
CSH2_k127_292402_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 504.0
CSH2_k127_292402_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000002304 145.0
CSH2_k127_292583_0 OmpA family K03286,K03640 - - 0.000000000000000000000000000000008691 143.0
CSH2_k127_2927998_0 CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 618.0
CSH2_k127_2930826_0 flavin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007827 264.0
CSH2_k127_2930826_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000009131 192.0
CSH2_k127_2930826_2 Metallo-beta-lactamase domain protein - - - 0.0000000000000000000001183 110.0
CSH2_k127_2934093_0 Histone deacetylase - - - 0.0000000000000000000000000000000000000000002402 163.0
CSH2_k127_2934093_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K06976 - - 0.000000000000000000000003213 108.0
CSH2_k127_2934093_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000003073 81.0
CSH2_k127_2968642_0 gas vesicle protein - - - 0.000000000000000000000000005716 115.0
CSH2_k127_2982270_0 Anaerobic glycerol-3-phosphate dehydrogenase, subunit K00112 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 336.0
CSH2_k127_2982270_1 glycerol3P_GlpC glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113,K11473 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 287.0
CSH2_k127_3010955_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 415.0
CSH2_k127_3010955_1 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000001212 222.0
CSH2_k127_3010955_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000001263 199.0
CSH2_k127_3010955_3 cyclic nucleotide-binding - - - 0.0000000000000003777 85.0
CSH2_k127_3010955_4 - - - - 0.0000009633 60.0
CSH2_k127_3015792_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 559.0
CSH2_k127_3015792_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 483.0
CSH2_k127_3015792_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 303.0
CSH2_k127_3026068_0 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 402.0
CSH2_k127_3026068_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000002665 160.0
CSH2_k127_3031855_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 315.0
CSH2_k127_3031855_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000019 184.0
CSH2_k127_3031855_2 Peptidyl-tRNA hydrolase K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000001825 176.0
CSH2_k127_3031855_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000001248 141.0
CSH2_k127_3031855_4 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000004234 124.0
CSH2_k127_3050525_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 483.0
CSH2_k127_3050525_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 381.0
CSH2_k127_306383_0 PFAM ATP phosphoribosyltransferase, catalytic region K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000002062 251.0
CSH2_k127_306383_1 PFAM metal-dependent phosphohydrolase HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000001062 229.0
CSH2_k127_306383_2 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000001046 175.0
CSH2_k127_3075944_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000009398 230.0
CSH2_k127_3075944_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000002287 174.0
CSH2_k127_3077504_0 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000831 280.0
CSH2_k127_3077504_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000002288 167.0
CSH2_k127_3077504_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000006023 67.0
CSH2_k127_3095654_0 Thermophilic metalloprotease (M29) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 587.0
CSH2_k127_3095654_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000002489 74.0
CSH2_k127_3110578_0 Flagellar hook-associated protein, FlgK K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 462.0
CSH2_k127_3110578_1 Flagellar hook-associated protein 3 K02397 - - 0.0000000000000000000000000000000000000000000000000000006075 204.0
CSH2_k127_311156_0 symporter activity K03307 - - 1.067e-216 687.0
CSH2_k127_311156_1 FecR protein - - - 0.000000001174 69.0
CSH2_k127_3119957_0 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 373.0
CSH2_k127_3119957_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 363.0
CSH2_k127_312214_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.25e-207 653.0
CSH2_k127_312214_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000109 189.0
CSH2_k127_312214_2 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000007028 154.0
CSH2_k127_312214_3 PFAM diacylglycerol kinase catalytic region - - - 0.0000000000000000000000000000000000003403 152.0
CSH2_k127_312214_4 Regulatory protein RecX K03565 - - 0.0000000000000000001761 96.0
CSH2_k127_312214_5 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.0002799 46.0
CSH2_k127_3139692_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 600.0
CSH2_k127_3139692_1 Ribosomal protein S1 K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 335.0
CSH2_k127_3139692_2 - - - - 0.0000000000000000008849 89.0
CSH2_k127_3154205_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 514.0
CSH2_k127_3154205_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 298.0
CSH2_k127_3155754_0 quinolinate synthetase A activity K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 430.0
CSH2_k127_3155754_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000006262 66.0
CSH2_k127_3214054_0 Pterin binding enzyme K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 301.0
CSH2_k127_3214054_1 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000007568 223.0
CSH2_k127_3214054_2 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000002254 219.0
CSH2_k127_3214965_0 methyltransferase K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 520.0
CSH2_k127_3214965_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 458.0
CSH2_k127_3214965_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000002742 151.0
CSH2_k127_3214965_3 TIGRFAM thiamine biosynthesis protein ThiS K03154 - - 0.0007619 44.0
CSH2_k127_3227046_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 357.0
CSH2_k127_3227046_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000003003 119.0
CSH2_k127_3237700_0 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 529.0
CSH2_k127_3237700_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 396.0
CSH2_k127_3237700_2 Adenine deaminase C-terminal domain K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 402.0
CSH2_k127_3255634_0 Adenylate guanylate cyclase catalytic domain protein K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 455.0
CSH2_k127_3255634_1 DHH family - - - 0.0000000000000000000000000000000000000000000000000000005873 202.0
CSH2_k127_3255634_2 Arginyl tRNA synthetase N terminal domain K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000001591 194.0
CSH2_k127_330733_0 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000002542 197.0
CSH2_k127_330733_1 homoserine transmembrane transporter activity K06895 - - 0.000000000000000000000000000335 122.0
CSH2_k127_33327_0 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000007861 137.0
CSH2_k127_33327_1 Belongs to the PdxA family K22024 - 1.1.1.408,1.1.1.409 0.00000000000000000004888 95.0
CSH2_k127_3354493_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 532.0
CSH2_k127_33587_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008597 265.0
CSH2_k127_33587_1 stage V sporulation protein D K03587,K08384 - 3.4.16.4 0.000008747 56.0
CSH2_k127_3363714_0 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 528.0
CSH2_k127_3380996_0 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 495.0
CSH2_k127_3380996_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 296.0
CSH2_k127_3380996_2 PFAM secretion protein HlyD family protein K01993 - - 0.0000000000000000000000000000000000000000000000003572 185.0
CSH2_k127_3380996_3 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.00000000000000000000000000000000000000000006454 163.0
CSH2_k127_3380996_4 outer membrane efflux protein - - - 0.0000000000000000000000001083 122.0
CSH2_k127_3380996_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000002585 86.0
CSH2_k127_3380996_6 ABC-2 family transporter protein - - - 0.0000000000003315 72.0
CSH2_k127_3401976_0 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000004941 210.0
CSH2_k127_3401976_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000005771 135.0
CSH2_k127_3412881_0 Glutathionylspermidine synthase preATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 444.0
CSH2_k127_3412881_1 Ion transport 2 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000626 232.0
CSH2_k127_3412881_2 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.00000000000000000000000000000000000000000000000002721 191.0
CSH2_k127_3412881_3 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000001893 150.0
CSH2_k127_3412881_4 Domain of Unknown Function (DUF350) K08989 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000007546 141.0
CSH2_k127_3412881_5 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.000000000000000000000000000001687 132.0
CSH2_k127_3412881_6 phospholipase K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000002253 100.0
CSH2_k127_3412881_7 - - - - 0.0000003791 59.0
CSH2_k127_3412881_8 Staphylococcal nuclease homologue - - - 0.0000009226 53.0
CSH2_k127_3412881_9 - - - - 0.00003737 50.0
CSH2_k127_341558_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000272 251.0
CSH2_k127_341558_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000006272 145.0
CSH2_k127_341558_2 Sporulation related domain - - - 0.0000004668 61.0
CSH2_k127_3428803_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 353.0
CSH2_k127_3428803_1 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000006907 135.0
CSH2_k127_3428803_2 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000006683 96.0
CSH2_k127_3432570_0 ABC transporter, permease protein K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 348.0
CSH2_k127_3432570_1 extracellular solute-binding protein, family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 323.0
CSH2_k127_3432570_2 Binding-protein-dependent transport system inner membrane component K15582 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000001483 127.0
CSH2_k127_3439337_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 410.0
CSH2_k127_3440532_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 336.0
CSH2_k127_3440532_1 PFAM Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000003681 237.0
CSH2_k127_3440532_2 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000615 64.0
CSH2_k127_3443818_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008919 512.0
CSH2_k127_3443818_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000006366 253.0
CSH2_k127_3449742_0 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002461 255.0
CSH2_k127_3449742_1 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005101 254.0
CSH2_k127_3459845_0 CoA carboxylase activity K01966,K01969 - 2.1.3.15,6.4.1.3,6.4.1.4 1.567e-224 706.0
CSH2_k127_3511516_0 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000005829 177.0
CSH2_k127_3511516_1 PFAM Stage II sporulation E family protein K07315 - 3.1.3.3 0.00000000000000000000000000000000007922 154.0
CSH2_k127_3511516_2 Sulfatase-modifying factor enzyme 1 K20333 - - 0.0000000000000000000000000000002178 138.0
CSH2_k127_3511516_3 DHH family - - - 0.0000000000000000000005025 99.0
CSH2_k127_3511881_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.7.99.1 5.128e-249 779.0
CSH2_k127_3511881_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 383.0
CSH2_k127_3511881_10 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000001268 103.0
CSH2_k127_3511881_11 Cyclic nucleotide-monophosphate binding domain K01420,K21563 - - 0.000000000000000000001255 101.0
CSH2_k127_3511881_12 Nuclease-related domain K07460 - - 0.00000000000000000002348 95.0
CSH2_k127_3511881_13 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000003016 79.0
CSH2_k127_3511881_14 FlhB HrpN YscU SpaS Family K04061 - - 0.00000000000005173 75.0
CSH2_k127_3511881_15 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0001682 46.0
CSH2_k127_3511881_2 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 311.0
CSH2_k127_3511881_3 Belongs to the RNA methyltransferase TrmD family K00554,K01770 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000001154 243.0
CSH2_k127_3511881_4 HD domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001343 236.0
CSH2_k127_3511881_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000005321 179.0
CSH2_k127_3511881_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000005048 153.0
CSH2_k127_3511881_7 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000003203 149.0
CSH2_k127_3511881_8 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000001166 132.0
CSH2_k127_3511881_9 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000009796 111.0
CSH2_k127_3528849_0 Queuosine biosynthesis protein QueC K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000002232 254.0
CSH2_k127_3528849_1 Competence protein - GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000002386 92.0
CSH2_k127_3531454_0 Protein of unknown function DUF111 K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000002966 224.0
CSH2_k127_3531454_1 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000006803 145.0
CSH2_k127_3536606_0 L-glutamate biosynthetic process K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 2.155e-294 926.0
CSH2_k127_3536606_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 1.345e-236 737.0
CSH2_k127_3588504_0 Carboxyl transferase domain K01615 - 4.1.1.70 2.103e-292 906.0
CSH2_k127_3588504_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 374.0
CSH2_k127_3588504_2 acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 299.0
CSH2_k127_3588504_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000003202 162.0
CSH2_k127_3588504_4 Biotin-requiring enzyme - - - 0.00000000000000000001075 93.0
CSH2_k127_3601283_0 secondary active sulfate transmembrane transporter activity K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 359.0
CSH2_k127_3601283_1 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 289.0
CSH2_k127_3601283_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000003285 181.0
CSH2_k127_3612369_0 nUDIX hydrolase K03574,K08320 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55,3.6.1.65 0.00000000000000000000000000000000000000001581 156.0
CSH2_k127_3612369_1 SMI1 / KNR4 family - - - 0.0009869 49.0
CSH2_k127_3612657_0 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008064 244.0
CSH2_k127_3622297_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 434.0
CSH2_k127_3622297_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 334.0
CSH2_k127_3622297_2 Nicotinamidase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000001312 238.0
CSH2_k127_3626380_0 HNH nucleases - - - 0.0000000000000000000000000000000000554 137.0
CSH2_k127_3626380_1 Tetratricopeptide repeat - - - 0.000000000000135 73.0
CSH2_k127_3629554_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000001051 239.0
CSH2_k127_3629554_1 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000007406 184.0
CSH2_k127_3629554_2 cytidylyl-transferase K07257 - - 0.000000000000000000000000000000000000000000001629 174.0
CSH2_k127_3629554_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000006393 126.0
CSH2_k127_3629554_4 spore coat polysaccharide biosynthesis protein K07257 - - 0.0000000002435 71.0
CSH2_k127_3629554_5 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.0000002133 62.0
CSH2_k127_3629611_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 389.0
CSH2_k127_3629611_1 transcriptional regulator K22294 - - 0.0000000000001631 79.0
CSH2_k127_3629611_2 efflux transmembrane transporter activity K12340 - - 0.00000322 57.0
CSH2_k127_3634596_0 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 315.0
CSH2_k127_3634596_1 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000003586 229.0
CSH2_k127_3635721_0 PAS fold - - - 0.000000000000000000000000000000002115 146.0
CSH2_k127_3640073_0 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000003764 168.0
CSH2_k127_3640073_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000001459 99.0
CSH2_k127_3640073_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000001699 74.0
CSH2_k127_3641291_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 317.0
CSH2_k127_3641291_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000006832 264.0
CSH2_k127_3641291_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002447 172.0
CSH2_k127_3641291_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.00000000000000000000000000000000000006317 146.0
CSH2_k127_3641291_4 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000000000000122 92.0
CSH2_k127_3644226_0 Ion transport 2 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 342.0
CSH2_k127_3644226_1 Component of the core of the flagella K02406 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002675 276.0
CSH2_k127_3646136_0 Belongs to the RtcB family K14415 - 6.5.1.3 2.071e-201 637.0
CSH2_k127_3646136_1 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000125 179.0
CSH2_k127_3652519_0 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 316.0
CSH2_k127_3652519_1 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000001211 231.0
CSH2_k127_3652519_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000003777 118.0
CSH2_k127_3654074_0 radical SAM domain protein K07739 - 2.3.1.48 0.000000000000000000000000008232 111.0
CSH2_k127_3654244_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 518.0
CSH2_k127_3654244_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000001291 139.0
CSH2_k127_3654244_2 Amidohydrolase - - - 0.00000000007717 63.0
CSH2_k127_3659734_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 321.0
CSH2_k127_3659734_1 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000037 229.0
CSH2_k127_3667461_0 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000005125 249.0
CSH2_k127_3667461_1 regulation of translation K05788 - - 0.00000000000000000000000000000005439 129.0
CSH2_k127_3670722_0 Glycosyltransferase K16703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 357.0
CSH2_k127_3670722_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000311 134.0
CSH2_k127_3670722_2 4Fe-4S binding domain - - - 0.000000000000000000003064 104.0
CSH2_k127_3670722_3 DEAD DEAH box helicase K05592 - 3.6.4.13 0.000000000000000006679 89.0
CSH2_k127_3671057_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 590.0
CSH2_k127_3671626_0 TIGRFAM N-acetyl sugar amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000156 238.0
CSH2_k127_3671626_1 acyl carrier protein - - - 0.000000000000000000002627 95.0
CSH2_k127_3671626_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000007613 93.0
CSH2_k127_3671626_3 TIGRFAM N-acetyl sugar amidotransferase - - - 0.0000000000000000116 84.0
CSH2_k127_3675491_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000001871 128.0
CSH2_k127_3675491_1 LysM domain protein - - - 0.000000001112 67.0
CSH2_k127_3684245_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 313.0
CSH2_k127_3684245_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004958 264.0
CSH2_k127_3684245_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000004962 246.0
CSH2_k127_3684245_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000007905 239.0
CSH2_k127_3684245_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001567 216.0
CSH2_k127_3684245_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000001959 214.0
CSH2_k127_3684245_6 phosphatidate cytidylyltransferase activity K00981 - 2.7.7.41 0.0000000000000000000000000000000005425 142.0
CSH2_k127_3684245_7 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000007819 62.0
CSH2_k127_3685136_0 Molecular chaperone. Has ATPase activity K04079 - - 7.508e-262 821.0
CSH2_k127_3685136_1 - - - - 0.00007344 45.0
CSH2_k127_3685136_2 dihydromethanopterin reductase activity - - - 0.0005311 42.0
CSH2_k127_3685722_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.55e-208 661.0
CSH2_k127_3685722_1 Amino acid permease - - - 5.65e-199 631.0
CSH2_k127_3685722_2 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000001332 237.0
CSH2_k127_3685722_3 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000003561 76.0
CSH2_k127_3691311_0 radical SAM domain protein K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 619.0
CSH2_k127_3691311_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002497 273.0
CSH2_k127_3691311_2 Alpha-2-Macroglobulin K06894 - - 0.000000001204 62.0
CSH2_k127_3694960_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 409.0
CSH2_k127_3694960_1 Fha domain - - - 0.0001077 53.0
CSH2_k127_3696731_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 474.0
CSH2_k127_3696731_1 Transcription factor zinc-finger K09981 - - 0.00000000000000000000006988 100.0
CSH2_k127_3696731_2 Cro/C1-type HTH DNA-binding domain - - - 0.000000000001892 74.0
CSH2_k127_3707127_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 7.904e-270 841.0
CSH2_k127_3707127_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 297.0
CSH2_k127_3707127_2 subunit (C K02119 - - 0.00000000000000000000000000000000000000000000006042 180.0
CSH2_k127_3707127_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000000000000000002974 159.0
CSH2_k127_3708032_0 Pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 455.0
CSH2_k127_3708032_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 308.0
CSH2_k127_3708032_2 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000361 215.0
CSH2_k127_3708032_3 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000004592 150.0
CSH2_k127_3717990_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 312.0
CSH2_k127_3717990_1 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 304.0
CSH2_k127_3717990_2 ABC transporter, ATP-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001289 269.0
CSH2_k127_3717990_3 Acetyl-CoA dehydrogenase C-terminal like K09456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004512 254.0
CSH2_k127_3717990_4 recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005227 256.0
CSH2_k127_3717990_5 SpoIID LytB domain protein K06381 - - 0.0000000000000000000000000000000000000000000000000003275 200.0
CSH2_k127_3717990_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000007501 186.0
CSH2_k127_3717990_7 outer membrane efflux protein - - - 0.00000000000000000002495 105.0
CSH2_k127_3741987_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000005319 226.0
CSH2_k127_3741987_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000002732 197.0
CSH2_k127_3741987_2 PFAM Sporulation and spore germination - - - 0.000000000000000569 88.0
CSH2_k127_3744547_0 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 413.0
CSH2_k127_3744547_1 PFAM FecR protein - - - 0.0000000000000000000000000000000000000000005798 179.0
CSH2_k127_3768093_0 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 386.0
CSH2_k127_3768093_1 redox protein regulator of disulfide bond formation K06889,K07397 - - 0.00000000000000004842 90.0
CSH2_k127_3774489_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 375.0
CSH2_k127_3774489_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000001314 115.0
CSH2_k127_3774489_2 Response regulator receiver domain K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000001074 114.0
CSH2_k127_380253_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000004899 163.0
CSH2_k127_381701_0 Firmicute fructose-1,6-bisphosphatase K04041 - 3.1.3.11 0.000000000000000000000000000000000000000000000000008557 184.0
CSH2_k127_3837768_0 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000002943 238.0
CSH2_k127_3837768_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000004873 132.0
CSH2_k127_3837768_2 TPR repeat - - - 0.000058 55.0
CSH2_k127_3848759_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 602.0
CSH2_k127_38501_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1071.0
CSH2_k127_38501_1 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 389.0
CSH2_k127_38501_2 Addiction module toxin RelE StbE family - - - 0.0000000000000000000000000000000009662 131.0
CSH2_k127_38501_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000001366 102.0
CSH2_k127_38501_4 Pfam:Pyridox_oxidase - - - 0.00000000000000000207 90.0
CSH2_k127_38501_5 Trm112p-like protein K09791 - - 0.000000000000000648 78.0
CSH2_k127_38501_6 peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 0.0001275 48.0
CSH2_k127_3852819_0 o-acetylhomoserine K01740 - 2.5.1.49 2.697e-214 671.0
CSH2_k127_3852819_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000002469 134.0
CSH2_k127_3852819_2 cysteine synthase K01738 - 2.5.1.47 0.0000000000008017 68.0
CSH2_k127_3854133_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 7.519e-239 747.0
CSH2_k127_3854133_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000003141 78.0
CSH2_k127_3858080_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 559.0
CSH2_k127_3858080_1 - - - - 0.00000000000000000000000000000004857 128.0
CSH2_k127_3866523_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 580.0
CSH2_k127_3866523_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000002361 204.0
CSH2_k127_3866523_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000498 200.0
CSH2_k127_3866523_3 - - - - 0.0000000000000000000002606 96.0
CSH2_k127_3866523_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000004031 88.0
CSH2_k127_3873583_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 297.0
CSH2_k127_3873583_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000002167 223.0
CSH2_k127_3873583_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.000001185 54.0
CSH2_k127_387712_0 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 322.0
CSH2_k127_387712_1 TIGRFAM flagellar biosynthetic protein FliS K02422 - - 0.00000000000000000000000000001518 123.0
CSH2_k127_38920_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000008502 242.0
CSH2_k127_38920_1 R3H domain protein K06346 - - 0.00000000000000000000000000000000000002748 150.0
CSH2_k127_39019_0 Sodium:solute symporter family K03307 - - 9.153e-203 640.0
CSH2_k127_39019_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 503.0
CSH2_k127_39019_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 417.0
CSH2_k127_39019_3 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 354.0
CSH2_k127_39019_4 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 302.0
CSH2_k127_39019_5 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 293.0
CSH2_k127_39019_6 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000193 265.0
CSH2_k127_3926585_0 PFAM WD40 domain protein beta Propeller - - - 0.0000000000000000000000000000000000004047 156.0
CSH2_k127_3926585_1 domain protein - - - 0.0000000000000000000000000000000005695 140.0
CSH2_k127_3927778_0 Male sterility protein K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 362.0
CSH2_k127_3927778_1 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000195 269.0
CSH2_k127_3927778_2 Elongator protein 3, MiaB family, Radical SAM K22318 - - 0.000000000000000000000000000000000000000000000000000000000001362 220.0
CSH2_k127_3928798_0 carbon starvation protein CstA K06200 - - 3.13e-277 859.0
CSH2_k127_3929976_0 zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000003945 232.0
CSH2_k127_3929976_2 Tetratricopeptide repeat - - - 0.000000000000000002655 99.0
CSH2_k127_3934343_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 1.415e-197 638.0
CSH2_k127_3934343_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000002095 192.0
CSH2_k127_3934343_2 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000001051 150.0
CSH2_k127_3934343_3 PFAM CheW domain protein K03408 - - 0.000000000000000000000000001128 125.0
CSH2_k127_3934665_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 514.0
CSH2_k127_3934665_1 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 474.0
CSH2_k127_3934665_2 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000001035 143.0
CSH2_k127_3934665_3 Phosphopantetheine attachment site - - - 0.00000000000000000000000000000002856 127.0
CSH2_k127_3934665_4 FabA-like domain - - - 0.000000000000000000001853 98.0
CSH2_k127_3934665_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000001168 76.0
CSH2_k127_3934891_0 COGs COG0673 dehydrogenase and related protein K16043 - 1.1.1.370 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 316.0
CSH2_k127_3934891_1 3-dehydroquinate synthase activity K01735,K13829 GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000001399 227.0
CSH2_k127_3947200_0 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 576.0
CSH2_k127_3947200_1 Aminotransferase K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 339.0
CSH2_k127_3947200_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003964 265.0
CSH2_k127_3947200_3 RNA-binding protein K06962 - - 0.0001866 50.0
CSH2_k127_3949780_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 292.0
CSH2_k127_3949780_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000003199 220.0
CSH2_k127_3949780_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000001829 214.0
CSH2_k127_3949780_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000001544 205.0
CSH2_k127_3949780_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000001424 155.0
CSH2_k127_3949780_5 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000313 135.0
CSH2_k127_3949780_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000001403 74.0
CSH2_k127_3950794_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 464.0
CSH2_k127_3953747_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000004481 209.0
CSH2_k127_3953747_1 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000001882 176.0
CSH2_k127_3955979_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002718 273.0
CSH2_k127_3966805_0 lycopene cyclase - - - 0.0000000000000000000000000000000000000000000000000002067 193.0
CSH2_k127_3966805_1 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000004221 140.0
CSH2_k127_3966805_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000002143 58.0
CSH2_k127_3971689_0 translation elongation factor K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 582.0
CSH2_k127_3972891_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 412.0
CSH2_k127_3972891_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000003107 197.0
CSH2_k127_3972891_2 NlpC/P60 family K13695 - - 0.0000000000000006069 91.0
CSH2_k127_3983006_0 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 398.0
CSH2_k127_3983006_1 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000002088 240.0
CSH2_k127_3986144_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000001793 112.0
CSH2_k127_3986144_1 ExbD TolR K03559 - - 0.00000000000000000002445 95.0
CSH2_k127_3986144_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000008084 59.0
CSH2_k127_3986144_3 - - - - 0.00009202 45.0
CSH2_k127_3986740_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000005985 200.0
CSH2_k127_3986740_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000021 157.0
CSH2_k127_399066_0 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 507.0
CSH2_k127_399066_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001854 276.0
CSH2_k127_399066_2 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000003021 209.0
CSH2_k127_399066_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000001298 202.0
CSH2_k127_3996048_0 TIGRFAM DNA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 287.0
CSH2_k127_3997302_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000002666 172.0
CSH2_k127_3997302_1 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000001881 153.0
CSH2_k127_3997302_2 - - - - 0.000000000000000002835 98.0
CSH2_k127_3999451_0 His Kinase A (phosphoacceptor) domain - - - 8.002e-214 696.0
CSH2_k127_3999451_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 456.0
CSH2_k127_3999451_2 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 431.0
CSH2_k127_3999451_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 353.0
CSH2_k127_3999451_4 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000001662 234.0
CSH2_k127_3999451_5 superoxide reductase activity K05919 - 1.15.1.2 0.000000000000000000000000000000000000000000000000000001883 195.0
CSH2_k127_3999713_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 4.65e-282 876.0
CSH2_k127_3999713_1 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 550.0
CSH2_k127_3999713_2 Curli production assembly/transport component CsgG - - - 0.000003606 58.0
CSH2_k127_3999713_3 PFAM response regulator receiver K07705 - - 0.00007501 53.0
CSH2_k127_4000114_0 - - - - 0.000000000000000000000006497 109.0
CSH2_k127_4000114_1 Curli production assembly/transport component CsgG - - - 0.0000000001931 74.0
CSH2_k127_4003081_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 521.0
CSH2_k127_4003081_1 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000006025 149.0
CSH2_k127_4003081_2 SMART CheW domain protein K03408 - - 0.000000000000000000000000000000000004008 143.0
CSH2_k127_4003081_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000002378 108.0
CSH2_k127_4003081_4 transporter antisigma-factor antagonist STAS - - - 0.0003037 48.0
CSH2_k127_4012201_0 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 437.0
CSH2_k127_4012201_1 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 401.0
CSH2_k127_402168_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 449.0
CSH2_k127_402168_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000004898 117.0
CSH2_k127_4040504_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000001158 122.0
CSH2_k127_4040504_1 COG0457 FOG TPR repeat - - - 0.00000116 59.0
CSH2_k127_404314_0 benzoate-CoA ligase K04110 - 6.2.1.25 5.923e-223 702.0
CSH2_k127_404314_1 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000006076 224.0
CSH2_k127_404314_2 - - - - 0.0000000000000000000000000002755 124.0
CSH2_k127_404314_3 Peptidase family M28 - - - 0.00000000173 71.0
CSH2_k127_4051179_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 2.933e-265 838.0
CSH2_k127_4051179_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 389.0
CSH2_k127_4051179_2 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001249 272.0
CSH2_k127_4051179_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000004392 191.0
CSH2_k127_4051179_4 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.000000000000000000000000000000000001661 143.0
CSH2_k127_4056449_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.924e-282 878.0
CSH2_k127_406476_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.049e-227 723.0
CSH2_k127_406476_1 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 376.0
CSH2_k127_406476_2 PFAM flavin reductase domain protein FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004047 273.0
CSH2_k127_406476_3 Fumarate K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000005306 250.0
CSH2_k127_406476_4 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000001029 222.0
CSH2_k127_406476_5 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000003132 178.0
CSH2_k127_406476_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000001463 132.0
CSH2_k127_4070350_0 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 454.0
CSH2_k127_4070350_1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000001579 81.0
CSH2_k127_4071604_0 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 378.0
CSH2_k127_4071604_1 N-6 DNA Methylase - - - 0.000000000001252 69.0
CSH2_k127_4071604_2 PFAM HI0933 family protein K07007 - - 0.00000000019 62.0
CSH2_k127_4081344_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 482.0
CSH2_k127_408919_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 361.0
CSH2_k127_408919_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 314.0
CSH2_k127_408919_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 293.0
CSH2_k127_408919_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000537 227.0
CSH2_k127_408919_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000001838 209.0
CSH2_k127_408919_5 YoaP-like - - - 0.0000003744 57.0
CSH2_k127_4090009_0 PFAM aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 303.0
CSH2_k127_4090009_1 PFAM Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000004971 165.0
CSH2_k127_4092446_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000002327 253.0
CSH2_k127_4092446_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000004024 243.0
CSH2_k127_4092446_2 Preprotein translocase subunit YajC K03210 - - 0.0000000000000000003577 91.0
CSH2_k127_4092446_3 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000002049 61.0
CSH2_k127_4102733_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000004659 218.0
CSH2_k127_4102733_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000298 155.0
CSH2_k127_4102733_2 Mammalian cell entry related domain protein K02067 - - 0.00000002884 63.0
CSH2_k127_4106729_0 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 462.0
CSH2_k127_4106729_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000001438 50.0
CSH2_k127_4106887_0 1-phosphatidylinositol-4-phosphate 5-kinase activity K14972 - - 0.0000000000000000000000000003617 122.0
CSH2_k127_4106887_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 0.0000003167 64.0
CSH2_k127_4128332_0 TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 556.0
CSH2_k127_4128332_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 485.0
CSH2_k127_4128332_2 TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 357.0
CSH2_k127_4128332_4 PAS fold - - - 0.000000000000000002678 100.0
CSH2_k127_4128442_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 447.0
CSH2_k127_4128442_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 357.0
CSH2_k127_4128442_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000003924 181.0
CSH2_k127_4128938_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 9.799e-257 803.0
CSH2_k127_4128938_1 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 301.0
CSH2_k127_4128938_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000246 274.0
CSH2_k127_4128938_3 manually curated - - - 0.0000002512 58.0
CSH2_k127_412918_0 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 420.0
CSH2_k127_412918_1 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000001536 124.0
CSH2_k127_412918_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000002899 87.0
CSH2_k127_412918_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000002323 62.0
CSH2_k127_4167327_0 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 365.0
CSH2_k127_4167327_1 Utp--glucose-1-phosphate uridylyltransferase K00972,K11442 - 2.7.7.23,2.7.7.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 321.0
CSH2_k127_4177182_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000006157 216.0
CSH2_k127_4177182_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000009892 164.0
CSH2_k127_4185303_0 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000021 107.0
CSH2_k127_4195558_0 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000004352 230.0
CSH2_k127_4195558_1 3-dehydroquinate synthase activity K01735,K13829 GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000402 162.0
CSH2_k127_4195558_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000003337 112.0
CSH2_k127_4195558_3 Hydrolase, NUDIX family - - - 0.000000000000000000000000005333 116.0
CSH2_k127_4197936_0 Pyruvate:ferredoxin oxidoreductase core domain II K03737 - 1.2.7.1 0.0 1334.0
CSH2_k127_420073_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001528 287.0
CSH2_k127_420073_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000002093 206.0
CSH2_k127_420073_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000377 194.0
CSH2_k127_420073_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000003666 137.0
CSH2_k127_420073_4 Ribosomal protein L33 K02913 - - 0.0000000000000003292 78.0
CSH2_k127_420073_5 cell redox homeostasis K02199 - - 0.0000000000001164 79.0
CSH2_k127_420073_6 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000004321 62.0
CSH2_k127_422453_0 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000009714 153.0
CSH2_k127_422453_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000004632 152.0
CSH2_k127_422453_2 aminoacyl-tRNA hydrolase activity K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000001577 142.0
CSH2_k127_4224612_0 cellulose binding - - - 0.000000000000000003013 100.0
CSH2_k127_4224612_1 UPF0761 membrane protein K07058 - - 0.0000000000000853 85.0
CSH2_k127_4224612_2 Virulence factor BrkB K07058 - - 0.000000004138 70.0
CSH2_k127_4224612_3 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0008902 49.0
CSH2_k127_4225798_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004496 265.0
CSH2_k127_4225798_1 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000002309 173.0
CSH2_k127_422788_0 COG3279 Response regulator of the LytR AlgR family - - - 0.000000000000007521 79.0
CSH2_k127_422788_1 photosystem II stabilization K02237 - - 0.000000001521 70.0
CSH2_k127_422788_2 antisigma factor binding K04749 - - 0.0000009684 56.0
CSH2_k127_4228872_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 9.75e-315 970.0
CSH2_k127_4228872_1 secondary active sulfate transmembrane transporter activity K06901 - - 0.0000000000000000000000000000000000000000000000000008656 187.0
CSH2_k127_4234238_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1253.0
CSH2_k127_4234238_1 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 293.0
CSH2_k127_4234238_2 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000000000000000000000003234 204.0
CSH2_k127_4234761_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 493.0
CSH2_k127_4234761_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000188 289.0
CSH2_k127_4234761_2 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001303 270.0
CSH2_k127_4234761_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.00000000000000000000000000000000000000000000004338 179.0
CSH2_k127_4235442_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 476.0
CSH2_k127_4235442_1 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 417.0
CSH2_k127_4235442_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000005783 225.0
CSH2_k127_4235442_3 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000002928 208.0
CSH2_k127_4235442_4 response regulator K13599 - - 0.0000000000000000000000000000000000000000000001259 173.0
CSH2_k127_4235442_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000001059 131.0
CSH2_k127_4235442_6 Protein conserved in bacteria K09986 - - 0.0000000000000002554 85.0
CSH2_k127_4235442_7 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000009022 79.0
CSH2_k127_4235442_8 - - - - 0.0001261 49.0
CSH2_k127_4243555_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 312.0
CSH2_k127_4243555_1 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000001312 178.0
CSH2_k127_4243555_2 DUF218 domain - - - 0.0000000000000000000000000000000000000117 154.0
CSH2_k127_4245009_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.00000000000000000000000000000000000000000000000000002214 199.0
CSH2_k127_4245341_0 Belongs to the peptidase S1C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 325.0
CSH2_k127_4245341_1 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000001071 73.0
CSH2_k127_4248291_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 463.0
CSH2_k127_4248291_1 Ferredoxin - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.00000000000000000000002553 99.0
CSH2_k127_4248291_2 Protein of unknown function (DUF3467) - - - 0.0000000000000000004368 90.0
CSH2_k127_4250430_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 435.0
CSH2_k127_4250430_1 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003434 263.0
CSH2_k127_425189_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 447.0
CSH2_k127_425189_1 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 383.0
CSH2_k127_4252127_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 305.0
CSH2_k127_4252127_1 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000001254 146.0
CSH2_k127_4252127_2 Lecithin:cholesterol acyltransferase - - - 0.000002364 59.0
CSH2_k127_4253886_0 Transferase K02527,K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000008275 238.0
CSH2_k127_4253886_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000002023 182.0
CSH2_k127_4253886_2 Glycosyl transferase, family 9 K02843 - - 0.00000000000000000000000000000000000000000000004105 184.0
CSH2_k127_4253886_3 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 - 5.4.99.5 0.00000000000000000000000000000000002158 138.0
CSH2_k127_4254805_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 306.0
CSH2_k127_4254805_1 PFAM YbbR family protein - - - 0.0000000977 63.0
CSH2_k127_4254805_2 Type II secretion system (T2SS), protein M K02462 - - 0.000001545 57.0
CSH2_k127_4262924_0 Domain of unknown function (DUF4332) - - - 0.000000000000000000000000000000000000000002166 159.0
CSH2_k127_4262924_1 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000005671 153.0
CSH2_k127_4262924_2 HAD-hyrolase-like K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.00000000000000000008609 94.0
CSH2_k127_4262924_3 - - - - 0.000000000000005747 79.0
CSH2_k127_4262924_4 - - - - 0.00000000171 64.0
CSH2_k127_4262924_5 HAD-hyrolase-like K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.0000003463 54.0
CSH2_k127_4268953_0 BadF BadG BcrA BcrD - - - 0.0 1353.0
CSH2_k127_4273586_0 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 604.0
CSH2_k127_4273586_1 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 445.0
CSH2_k127_4273586_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 436.0
CSH2_k127_4273586_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 426.0
CSH2_k127_4273586_4 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 357.0
CSH2_k127_4273586_5 Belongs to the UPF0311 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002229 245.0
CSH2_k127_4273586_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000003362 112.0
CSH2_k127_4285439_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 1.583e-312 979.0
CSH2_k127_4285439_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 352.0
CSH2_k127_428907_0 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 571.0
CSH2_k127_428907_1 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 305.0
CSH2_k127_428907_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02017,K02045,K15497 - 3.6.3.25,3.6.3.29,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 300.0
CSH2_k127_428907_3 Binding-protein-dependent transport system inner membrane component K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000003664 220.0
CSH2_k127_428907_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000004603 178.0
CSH2_k127_428907_5 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000003222 91.0
CSH2_k127_428907_6 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP-binding K00158 - 1.2.3.3 0.000000000001133 69.0
CSH2_k127_4290255_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 422.0
CSH2_k127_4290255_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 412.0
CSH2_k127_4290255_2 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 392.0
CSH2_k127_4290255_3 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000001247 131.0
CSH2_k127_4290802_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002519 261.0
CSH2_k127_4290802_1 Metallo-beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 256.0
CSH2_k127_4294040_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 334.0
CSH2_k127_4294040_1 rRNA (uridine-N3-)-methyltransferase activity K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000001487 269.0
CSH2_k127_4296584_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 413.0
CSH2_k127_4296584_1 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000007909 221.0
CSH2_k127_4296584_2 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000001205 160.0
CSH2_k127_4296584_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000002094 116.0
CSH2_k127_4296584_4 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000002673 85.0
CSH2_k127_4296584_5 PFAM Tetratricopeptide repeat - - - 0.00003546 55.0
CSH2_k127_429731_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000009595 193.0
CSH2_k127_429731_1 Cupin domain - - - 0.000000000000000000000000000000000000000000008079 165.0
CSH2_k127_429731_2 Aldolase/RraA - - - 0.00000000000000000000000000000000003686 136.0
CSH2_k127_4303115_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 583.0
CSH2_k127_4303115_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 531.0
CSH2_k127_4303115_2 FAD dependent oxidoreductase K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 422.0
CSH2_k127_4303115_3 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009798 282.0
CSH2_k127_4303115_4 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000006124 236.0
CSH2_k127_4303115_5 GTPase activity K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000004075 237.0
CSH2_k127_4303115_6 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.0000000000000000000000000000002466 125.0
CSH2_k127_4303115_7 Transcriptional regulator, GntR family - - - 0.00000000000000138 78.0
CSH2_k127_4304533_0 4Fe-4S dicluster domain - - - 3.004e-273 848.0
CSH2_k127_4304533_1 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 338.0
CSH2_k127_4304533_2 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000006305 98.0
CSH2_k127_4304533_3 - - - - 0.000000000009154 69.0
CSH2_k127_4311022_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 508.0
CSH2_k127_4311022_1 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 410.0
CSH2_k127_4311022_2 - - - - 0.00000000000001123 78.0
CSH2_k127_4311022_3 Peptidase M16 inactive domain K07263 - - 0.000000002371 66.0
CSH2_k127_4312887_0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 302.0
CSH2_k127_4312887_1 Domain of unknown function (DUF4954) - - - 0.000000000000000000000000009334 120.0
CSH2_k127_43159_0 Phosphate acyltransferases K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 426.0
CSH2_k127_4322131_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004464 245.0
CSH2_k127_4322131_1 cobalt ion transport K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000004249 146.0
CSH2_k127_4322131_2 cobalt ion transport K02009 - - 0.0000000000000000000004486 99.0
CSH2_k127_4322131_3 Predicted periplasmic lipoprotein (DUF2279) - - - 0.000000000000000000001924 106.0
CSH2_k127_4322623_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 556.0
CSH2_k127_4326820_0 protein conserved in bacteria K09859 - - 0.00000000000000000003577 101.0
CSH2_k127_4326820_1 Collagen-binding surface adhesin SpaP (Antigen I II family) K07337 - - 0.00000000000000005181 88.0
CSH2_k127_4326820_2 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000109 92.0
CSH2_k127_4329986_0 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 462.0
CSH2_k127_4329986_1 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000002614 130.0
CSH2_k127_4329986_2 Cupin domain - - - 0.00000000000000000009325 89.0
CSH2_k127_433086_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 498.0
CSH2_k127_433296_0 AMP-binding enzyme C-terminal domain K02363,K04116 - 2.7.7.58,6.3.2.14 2.116e-262 818.0
CSH2_k127_433296_1 Uncharacterised protein family (UPF0261) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 454.0
CSH2_k127_433296_2 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 433.0
CSH2_k127_433296_3 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.000000000000001567 79.0
CSH2_k127_4340081_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 307.0
CSH2_k127_4340081_1 AAA domain K03582 - 3.1.11.5 0.00000000000000000000000000000000872 130.0
CSH2_k127_4341797_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 485.0
CSH2_k127_4341797_1 chemotaxis protein K03407 - 2.7.13.3 0.0000000000000000000000000000003845 130.0
CSH2_k127_4341797_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000003324 72.0
CSH2_k127_4346524_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.579e-267 831.0
CSH2_k127_4346524_1 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 7.838e-249 777.0
CSH2_k127_4346524_2 GntR family - - - 0.00000000000000000000000000000000000000000000000000007684 194.0
CSH2_k127_4346524_3 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000001479 180.0
CSH2_k127_4356219_0 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 390.0
CSH2_k127_4356219_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.000000000000000000000000000000182 124.0
CSH2_k127_4365117_0 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 307.0
CSH2_k127_4365117_1 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000001425 146.0
CSH2_k127_4375552_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 2.887e-241 750.0
CSH2_k127_4375552_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 581.0
CSH2_k127_4375552_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 410.0
CSH2_k127_4375552_3 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 378.0
CSH2_k127_4375552_4 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 327.0
CSH2_k127_4375552_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000001778 104.0
CSH2_k127_4400979_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 351.0
CSH2_k127_4400979_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008188 277.0
CSH2_k127_4401243_0 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000006833 207.0
CSH2_k127_4401243_1 GAF domain - - - 0.0000000000001629 81.0
CSH2_k127_4406432_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 420.0
CSH2_k127_4406432_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009853 284.0
CSH2_k127_4406432_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000002952 250.0
CSH2_k127_4413064_0 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 329.0
CSH2_k127_4413064_1 ABC 3 transport family protein K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 321.0
CSH2_k127_4413064_2 K06861 lipopolysaccharide export system ATP-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 308.0
CSH2_k127_4413064_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 293.0
CSH2_k127_4413064_4 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 300.0
CSH2_k127_4413064_5 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000003288 239.0
CSH2_k127_4413064_6 TIGRFAM Phosphotransferase System HPr (HPr) Family K11189 - - 0.0000000000000000002669 90.0
CSH2_k127_4413064_7 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000009066 93.0
CSH2_k127_4413064_8 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.0000000003247 72.0
CSH2_k127_4413064_9 Lipopolysaccharide-assembly, LptC-related K09774,K11719 - - 0.00000000491 64.0
CSH2_k127_4431623_0 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 498.0
CSH2_k127_4431623_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000002529 212.0
CSH2_k127_4440264_0 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000462 285.0
CSH2_k127_4440264_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001104 149.0
CSH2_k127_4449144_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 536.0
CSH2_k127_4449144_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000004795 206.0
CSH2_k127_4470828_0 peptidase M23 - - - 0.000000000000000000000000000000009289 143.0
CSH2_k127_4470828_1 ECF sigma factor K03088 - - 0.0000000001426 68.0
CSH2_k127_4470828_2 ATP-independent chaperone mediated protein folding K02005 - - 0.0000466 52.0
CSH2_k127_4476008_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 530.0
CSH2_k127_4479061_0 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000002073 213.0
CSH2_k127_4479061_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000002984 191.0
CSH2_k127_4479061_2 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000002046 136.0
CSH2_k127_448199_0 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006 287.0
CSH2_k127_448199_1 FecR protein - - - 0.0004664 51.0
CSH2_k127_4488076_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.674e-265 839.0
CSH2_k127_4488076_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 593.0
CSH2_k127_4488076_2 CO dehydrogenase flavoprotein C-terminal domain K03519,K13479 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000008188 231.0
CSH2_k127_4488076_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000003292 213.0
CSH2_k127_4488076_4 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000004123 209.0
CSH2_k127_4488076_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000002392 168.0
CSH2_k127_4488076_6 PFAM Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000006349 165.0
CSH2_k127_4495909_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.814e-249 781.0
CSH2_k127_4495909_1 Diguanylate cyclase - - - 0.000000000000000000000004443 107.0
CSH2_k127_4495909_2 PFAM Acetyl-CoA hydrolase transferase - - - 0.00000000000000000004781 94.0
CSH2_k127_4513207_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1320.0
CSH2_k127_4513207_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 6.149e-270 840.0
CSH2_k127_4513207_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003725 245.0
CSH2_k127_4513207_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000006779 213.0
CSH2_k127_4513207_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000004446 143.0
CSH2_k127_4513207_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000001502 121.0
CSH2_k127_4526146_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 602.0
CSH2_k127_4526146_1 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 299.0
CSH2_k127_4526146_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003127 292.0
CSH2_k127_4526146_3 CHASE3 domain - - - 0.0000000000000000000000000000000000000000000000000001528 198.0
CSH2_k127_4526146_4 TfoX N-terminal domain - - - 0.0000000000000000000000000000000000000006546 150.0
CSH2_k127_4536086_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 331.0
CSH2_k127_4536086_1 epimerase dehydratase family K01784,K08679 - 5.1.3.2,5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 259.0
CSH2_k127_4536086_2 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001835 247.0
CSH2_k127_4536086_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000001142 176.0
CSH2_k127_4536086_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000001942 140.0
CSH2_k127_4536086_5 Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)- L-lysine intermediate to form hypusine, an essential post- translational modification only found in mature eIF-5A factor K06072 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016491,GO:0016705,GO:0018193,GO:0018205,GO:0019135,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0055114,GO:0071704,GO:1901564 1.14.99.29 0.000004502 56.0
CSH2_k127_4545372_0 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000006569 196.0
CSH2_k127_4545372_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000001986 178.0
CSH2_k127_4562014_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 2.437e-255 802.0
CSH2_k127_4572694_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.413e-241 758.0
CSH2_k127_4572694_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000002658 225.0
CSH2_k127_4572694_2 LexA-binding, inner membrane-associated putative hydrolase - - - 0.000128 53.0
CSH2_k127_458693_0 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 587.0
CSH2_k127_458693_1 LUD domain - - - 0.000000000000000000000000000000000000000000000000000000000000008474 223.0
CSH2_k127_458693_2 (FHA) domain - - - 0.00002443 47.0
CSH2_k127_4587478_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 361.0
CSH2_k127_4587478_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007161 258.0
CSH2_k127_4587478_2 rRNA binding K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.0000000000000000000000000000000000000000000000000000000000000046 222.0
CSH2_k127_4587478_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000001331 184.0
CSH2_k127_4587478_4 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000329 183.0
CSH2_k127_4587478_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000008005 143.0
CSH2_k127_4587478_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000001056 109.0
CSH2_k127_4587478_7 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000005678 98.0
CSH2_k127_4588581_0 Aldehyde dehydrogenase family K00128,K00129 - 1.2.1.3,1.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 455.0
CSH2_k127_4588581_1 dehydratase - - - 0.0000000000000000227 85.0
CSH2_k127_4591199_0 - - - - 0.000000000000000000000000000000000000000000001014 169.0
CSH2_k127_4591199_1 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000005205 91.0
CSH2_k127_4591199_2 - - - - 0.000000000000004878 79.0
CSH2_k127_4591199_3 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY - GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0007154,GO:0007165,GO:0008150,GO:0008194,GO:0008375,GO:0009719,GO:0009725,GO:0009735,GO:0009736,GO:0009739,GO:0009740,GO:0009755,GO:0009937,GO:0009938,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010476,GO:0010646,GO:0010648,GO:0016262,GO:0016740,GO:0016757,GO:0016758,GO:0019222,GO:0023051,GO:0023052,GO:0023057,GO:0031323,GO:0032870,GO:0033993,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071310,GO:0071368,GO:0071370,GO:0071396,GO:0071495,GO:0140096,GO:1901700,GO:1901701,GO:2000377 - 0.00002389 53.0
CSH2_k127_4591199_4 PFAM Uncharacterised protein family UPF0150 - - - 0.0001545 47.0
CSH2_k127_4612118_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 594.0
CSH2_k127_4620626_0 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 344.0
CSH2_k127_4620626_1 Flagellar hook-associated protein 3 K02397 - - 0.000000000000000000000000000000000000000000000000000002977 201.0
CSH2_k127_4620626_2 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000008478 185.0
CSH2_k127_4637813_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 426.0
CSH2_k127_4637813_1 Organic solvent tolerance protein OstA K04744 - - 0.00000000000000000006564 106.0
CSH2_k127_4637813_2 Sel1 domain protein repeat-containing protein K07126 - - 0.000000005999 66.0
CSH2_k127_4686996_0 Domain of unknown function (DUF3492) K21011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 344.0
CSH2_k127_4686996_1 Putative exopolysaccharide Exporter (EPS-E) K21012 - - 0.0000000000000000000000000000001056 134.0
CSH2_k127_4689394_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.681e-231 733.0
CSH2_k127_4689394_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 379.0
CSH2_k127_4689394_2 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 376.0
CSH2_k127_4689394_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000001088 203.0
CSH2_k127_4689394_4 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000001252 138.0
CSH2_k127_4689394_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000001337 128.0
CSH2_k127_4689394_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000006567 94.0
CSH2_k127_4695001_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 436.0
CSH2_k127_4695001_1 - - - - 0.000000000000001029 89.0
CSH2_k127_4696656_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 529.0
CSH2_k127_4696656_1 Peptidase, M23 - - - 0.00000000000000000000000000000000000000000000000000968 190.0
CSH2_k127_4696656_2 Tetratricopeptide repeat - - - 0.0001022 54.0
CSH2_k127_4706928_0 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 526.0
CSH2_k127_4706928_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000001153 192.0
CSH2_k127_4706928_2 PFAM VanW family protein - - - 0.000000000000000000000000001198 117.0
CSH2_k127_4706928_3 Phosphopantetheine attachment site - - - 0.000000000000006868 78.0
CSH2_k127_4737047_0 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 492.0
CSH2_k127_4737047_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 474.0
CSH2_k127_4737047_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 443.0
CSH2_k127_4737047_3 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000009101 121.0
CSH2_k127_4737047_4 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000001035 128.0
CSH2_k127_4737047_5 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000005668 110.0
CSH2_k127_4741264_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 465.0
CSH2_k127_4741264_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 364.0
CSH2_k127_4741264_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 297.0
CSH2_k127_4741264_3 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000002662 86.0
CSH2_k127_4741264_4 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00003428 49.0
CSH2_k127_47473_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.075e-224 714.0
CSH2_k127_47473_1 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000009698 216.0
CSH2_k127_47473_2 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000000005289 203.0
CSH2_k127_47473_3 STAS domain K04749,K06378 - - 0.00000000004313 68.0
CSH2_k127_4760022_1 von Willebrand factor, type A - - - 0.0000003655 63.0
CSH2_k127_4791952_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 357.0
CSH2_k127_4791952_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 294.0
CSH2_k127_4791952_2 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000005999 201.0
CSH2_k127_4792144_0 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000000000000000000000000000000000001627 166.0
CSH2_k127_4792144_1 General secretion pathway protein F K02455,K02653 - - 0.00000000000404 71.0
CSH2_k127_4792144_2 Type II secretion system (T2SS), protein J K02459 - - 0.0000000001454 70.0
CSH2_k127_4792144_3 Type II secretion system (T2SS), protein K - - - 0.000000000709 68.0
CSH2_k127_4798377_0 FMN binding - - - 1.102e-253 803.0
CSH2_k127_4798377_1 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 444.0
CSH2_k127_4798377_2 N-4 methylation of cytosine K00571,K03497 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 385.0
CSH2_k127_4808721_0 PFAM Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000001141 126.0
CSH2_k127_4808721_1 Tetratricopeptide repeat - - - 0.0000000001087 71.0
CSH2_k127_4808721_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - 0.00000003187 66.0
CSH2_k127_4820147_0 Peptidase family M3 K01392 - 3.4.24.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 565.0
CSH2_k127_4820147_1 Family 5 K15580 - - 0.00000000000000000000000000000000000000000000000001641 184.0
CSH2_k127_4829769_0 PFAM Glycoside hydrolase 15-related - - - 0.000000000288 72.0
CSH2_k127_4829769_1 STAS domain K04749 - - 0.000000001221 63.0
CSH2_k127_4837173_0 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 473.0
CSH2_k127_4837173_1 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000008675 251.0
CSH2_k127_4837173_2 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001755 240.0
CSH2_k127_4838347_0 heme-copper terminal oxidase activity K02274 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 1.457e-212 668.0
CSH2_k127_4838347_1 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000004987 186.0
CSH2_k127_4838347_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000009384 160.0
CSH2_k127_4838347_3 heme-copper terminal oxidase activity K02274 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.0000000000000000756 82.0
CSH2_k127_4838347_4 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000003672 62.0
CSH2_k127_4841008_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 3.528e-209 656.0
CSH2_k127_4841008_1 aminotransferase, class I and II K11358 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 433.0
CSH2_k127_4841008_2 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000006241 218.0
CSH2_k127_4841008_3 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000005628 163.0
CSH2_k127_4841008_4 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000509 147.0
CSH2_k127_4841008_5 - - - - 0.000006736 51.0
CSH2_k127_484306_0 cell shape determining protein, MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 466.0
CSH2_k127_484306_1 Penicillin-binding Protein K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 392.0
CSH2_k127_484306_2 Belongs to the SEDS family. MrdB RodA subfamily K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 319.0
CSH2_k127_484306_3 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000002286 181.0
CSH2_k127_484306_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000007762 173.0
CSH2_k127_484306_5 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000009126 161.0
CSH2_k127_484306_6 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000001042 104.0
CSH2_k127_484306_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K11210 - - 0.000000000005434 70.0
CSH2_k127_484306_8 rod shape-determining protein MreD K03571 - - 0.000000001786 65.0
CSH2_k127_4847040_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 472.0
CSH2_k127_4847040_1 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001763 282.0
CSH2_k127_4861513_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 342.0
CSH2_k127_4861513_1 Pseudouridine synthase K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 292.0
CSH2_k127_4861513_2 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000001513 106.0
CSH2_k127_4863575_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 601.0
CSH2_k127_4884887_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 500.0
CSH2_k127_4884887_1 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000005013 179.0
CSH2_k127_4884887_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000121 169.0
CSH2_k127_4884887_3 Sigma factor PP2C-like phosphatases - - - 0.0000000000000006871 86.0
CSH2_k127_4888450_0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 327.0
CSH2_k127_4904533_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 304.0
CSH2_k127_4904533_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000007452 193.0
CSH2_k127_4927809_0 type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001864 285.0
CSH2_k127_4927809_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000479 245.0
CSH2_k127_4927809_2 SMART PDZ DHR GLGF domain protein K02452 - - 0.0000000000000000001273 97.0
CSH2_k127_4934798_0 lysine 2,3-aminomutase activity K01843,K19810 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 537.0
CSH2_k127_4934798_1 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 399.0
CSH2_k127_4934798_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000002889 286.0
CSH2_k127_4936196_0 Belongs to the ClpA ClpB family K03696 - - 1.604e-266 844.0
CSH2_k127_4936196_1 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity K19405 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.00000000000000000000001833 105.0
CSH2_k127_4938564_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 402.0
CSH2_k127_4939897_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 414.0
CSH2_k127_4939897_1 TPM domain K06872 - - 0.0000000000000000000000000000002338 125.0
CSH2_k127_4939897_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.00005266 52.0
CSH2_k127_4949066_0 TIGRFAM cysteine desulfurase family protein K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 359.0
CSH2_k127_4949066_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001173 268.0
CSH2_k127_4949066_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087,K20447 - 1.17.1.4,1.17.1.5 0.00000000000000000000000000000000000000000000000000000003119 200.0
CSH2_k127_4949066_3 - - - - 0.00000000000000000000000000000000392 136.0
CSH2_k127_4959528_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003066 271.0
CSH2_k127_4959528_1 Cysteine-rich secretory protein family - - - 0.00000000003355 74.0
CSH2_k127_4966352_0 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 313.0
CSH2_k127_4966352_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000002847 174.0
CSH2_k127_4966352_2 Fibronectin type III domain protein - - - 0.000000000000000000000000000002521 136.0
CSH2_k127_4966352_3 AntiSigma factor - - - 0.00000000000000000000000000002749 127.0
CSH2_k127_4970168_0 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 348.0
CSH2_k127_4970168_1 PFAM ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 290.0
CSH2_k127_4970168_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006891 256.0
CSH2_k127_4980823_0 Universal stress protein family - - - 0.00000000000000000000000000000000000000003559 157.0
CSH2_k127_4980823_1 Histidine kinase - - - 0.0000000000000000000000000000001469 137.0
CSH2_k127_4980823_2 FMN binding - - - 0.0000000000000000000000000004164 119.0
CSH2_k127_4980823_3 AAA domain (dynein-related subfamily) K03924 - - 0.00000000000000000007153 104.0
CSH2_k127_4980823_4 PFAM Late competence development protein ComFB K02241 - - 0.000000000000004005 82.0
CSH2_k127_4983969_0 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 360.0
CSH2_k127_4983969_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002564 246.0
CSH2_k127_4986932_1 Metallo-beta-lactamase superfamily - - - 0.00000000000002309 81.0
CSH2_k127_4994388_0 TonB-dependent receptor plug - - - 0.000000000000003257 89.0
CSH2_k127_5011688_0 RNA polymerase sigma-70 factor K03088 - - 0.00000003423 62.0
CSH2_k127_5011688_1 FecR protein - - - 0.000001016 60.0
CSH2_k127_5019578_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 291.0
CSH2_k127_5019857_0 - K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 550.0
CSH2_k127_5019857_1 sulfur carrier activity - - - 0.0000000000000000000000025 105.0
CSH2_k127_5019857_2 iron-sulfur transferase activity K13819 - - 0.000000000000000807 79.0
CSH2_k127_5019937_0 4Fe-4S binding domain K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 332.0
CSH2_k127_5019937_1 - - - - 0.0000000000000000000000000000000187 131.0
CSH2_k127_502533_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000009887 210.0
CSH2_k127_502533_1 glycyl-radical enzyme activating activity K04069 - 1.97.1.4 0.000000000000000000000000000000000000002986 147.0
CSH2_k127_502533_2 Polymer-forming cytoskeletal - - - 0.00000000000000000000000001179 115.0
CSH2_k127_502533_3 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000002533 86.0
CSH2_k127_502533_4 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K04749 - - 0.0000009179 55.0
CSH2_k127_5071605_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 389.0
CSH2_k127_5071605_1 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 - 0.000000000000000001109 95.0
CSH2_k127_5071605_2 - - - - 0.0006342 51.0
CSH2_k127_5082370_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 473.0
CSH2_k127_5082370_1 Menaquinone biosynthesis K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 346.0
CSH2_k127_5082370_2 glycolate biosynthetic process K01091,K18979 - 1.17.99.6,3.1.3.18 0.0000000000000000000000000000000000000000000000000000008027 199.0
CSH2_k127_5082370_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000001779 179.0
CSH2_k127_5082370_4 Histidine kinase - - - 0.000000000000000008865 93.0
CSH2_k127_5084220_0 Component of the core of the flagella K02406 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 350.0
CSH2_k127_5084220_1 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000002361 241.0
CSH2_k127_5084220_2 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000002657 179.0
CSH2_k127_5088214_0 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 429.0
CSH2_k127_5088214_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 295.0
CSH2_k127_5088214_2 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009893 271.0
CSH2_k127_5088214_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000003002 171.0
CSH2_k127_5088214_4 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000002241 126.0
CSH2_k127_5093366_0 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000003269 129.0
CSH2_k127_5093366_1 peptidylprolyl isomerase K03769,K07533 - 5.2.1.8 0.000000000000000000000000000009418 131.0
CSH2_k127_5095104_0 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000662 134.0
CSH2_k127_5095104_1 ABC transporter K02065 - - 0.00000000000000000000000005905 117.0
CSH2_k127_5100188_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000001638 229.0
CSH2_k127_5100188_1 Eukaryotic integral membrane protein (DUF1751) K09650 - 3.4.21.105 0.0000000000000000000000000000000002519 144.0
CSH2_k127_5101139_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001121 280.0
CSH2_k127_5101139_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000007271 225.0
CSH2_k127_5101139_2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000002899 102.0
CSH2_k127_5101139_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000001176 59.0
CSH2_k127_510137_0 hydrolase of the alpha beta-hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001558 278.0
CSH2_k127_510137_1 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002591 256.0
CSH2_k127_510137_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005785 249.0
CSH2_k127_510137_3 Histidine kinase K07646 - 2.7.13.3 0.00000000000000006481 90.0
CSH2_k127_510137_4 HEAT repeats - - - 0.0000000000000006187 89.0
CSH2_k127_510137_5 Protein of unknown function (DUF1232) - - - 0.000000000009369 70.0
CSH2_k127_5105539_0 VWA containing CoxE family protein K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 582.0
CSH2_k127_5105539_1 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 454.0
CSH2_k127_5105539_2 Predicted periplasmic lipoprotein (DUF2279) - - - 0.000000000000000000002855 105.0
CSH2_k127_5144913_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 284.0
CSH2_k127_5144913_1 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000000006005 207.0
CSH2_k127_5144913_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000001434 85.0
CSH2_k127_5146603_0 Protein of unknown function DUF115 - - - 0.00000000000000000000000000000000000000000000000000000000000000004584 240.0
CSH2_k127_5147792_0 GTP-binding protein TypA K06207 - - 3.085e-222 698.0
CSH2_k127_515064_0 PFAM import inner membrane translocase, subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 304.0
CSH2_k127_515064_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000266 273.0
CSH2_k127_515064_2 Alpha/beta hydrolase of unknown function (DUF915) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003844 259.0
CSH2_k127_515064_3 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000001111 234.0
CSH2_k127_5152500_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003079 269.0
CSH2_k127_5152500_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004509 261.0
CSH2_k127_5152500_2 - - - - 0.0001334 53.0
CSH2_k127_5152500_3 PilZ domain - - - 0.0002462 50.0
CSH2_k127_5152500_4 MlaD protein K02067 - - 0.0003508 50.0
CSH2_k127_5163305_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000009516 226.0
CSH2_k127_5163305_1 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000001983 153.0
CSH2_k127_5163305_2 Tetratricopeptide repeat domain protein - - - 0.00001718 57.0
CSH2_k127_5167446_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 267.0
CSH2_k127_5167446_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000001662 162.0
CSH2_k127_5167446_2 Tetratricopeptide repeat - - - 0.00000000000000000001955 100.0
CSH2_k127_5171637_0 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000007957 248.0
CSH2_k127_5171637_1 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000008967 214.0
CSH2_k127_5173437_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K12142,K15830 GO:0003674,GO:0005488,GO:0016151,GO:0043167,GO:0043169,GO:0046872,GO:0046914 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 289.0
CSH2_k127_5173437_1 Belongs to the complex I 20 kDa subunit family - - - 0.00000000000000000000000000000000000000000000000000000000000000000007068 235.0
CSH2_k127_5173437_2 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14087 - - 0.000000000000000000000000000000000000000000000000000000000001356 220.0
CSH2_k127_5173437_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000911 120.0
CSH2_k127_5173437_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.000000000000000000001061 98.0
CSH2_k127_5173437_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.000000000000000002814 85.0
CSH2_k127_5175580_0 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000002956 194.0
CSH2_k127_5175580_1 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000001199 146.0
CSH2_k127_5182495_0 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 381.0
CSH2_k127_5182495_1 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001733 271.0
CSH2_k127_5182495_2 - - - - 0.000000000000000000000001437 105.0
CSH2_k127_5182495_3 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000008387 109.0
CSH2_k127_5185781_0 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 350.0
CSH2_k127_5185781_1 COGs COG4905 membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002055 236.0
CSH2_k127_5185781_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000004476 213.0
CSH2_k127_5210731_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 431.0
CSH2_k127_5210731_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 317.0
CSH2_k127_5210731_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000803 220.0
CSH2_k127_5210731_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000008662 153.0
CSH2_k127_5210731_4 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000005171 85.0
CSH2_k127_5222155_0 TIGRFAM ATP-dependent helicase HrpA K03578,K03579 - 3.6.4.13 0.0 1155.0
CSH2_k127_5222155_1 ATP-grasp domain K01903 - 6.2.1.5 3.172e-206 644.0
CSH2_k127_5222155_2 CoA-ligase K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 502.0
CSH2_k127_523213_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 302.0
CSH2_k127_523213_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000235 156.0
CSH2_k127_5256847_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000436 250.0
CSH2_k127_5256847_1 regulation of response to stimulus K20276 - - 0.00000000000000000000000000000000000005352 149.0
CSH2_k127_5256847_2 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000001394 96.0
CSH2_k127_5262241_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 461.0
CSH2_k127_5262241_1 cheY-homologous receiver domain - - - 0.00000000000000000000000000000197 123.0
CSH2_k127_5262241_2 Histidine kinase - - - 0.0000000000000000000608 91.0
CSH2_k127_5291989_0 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 455.0
CSH2_k127_5291989_1 response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000001143 214.0
CSH2_k127_5291989_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000001622 106.0
CSH2_k127_5296053_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 293.0
CSH2_k127_5296053_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000002049 246.0
CSH2_k127_5296053_2 - - - - 0.0000000000000000000000433 107.0
CSH2_k127_5296053_3 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.00000000000002426 82.0
CSH2_k127_5296053_4 - - - - 0.0000000001983 65.0
CSH2_k127_5296936_0 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000000000000000000000000000007426 210.0
CSH2_k127_5296936_1 TIGRFAM competence damage-inducible protein CinA K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000000000000000000000000000000000001205 150.0
CSH2_k127_5296936_2 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000000000001939 119.0
CSH2_k127_5304967_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 527.0
CSH2_k127_5304967_1 Acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000002091 143.0
CSH2_k127_5318908_0 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 518.0
CSH2_k127_5318908_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K04108 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000004461 263.0
CSH2_k127_5318908_2 - - - - 0.000003138 50.0
CSH2_k127_5325988_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.597e-226 709.0
CSH2_k127_5325988_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.072e-216 682.0
CSH2_k127_5325988_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000009644 188.0
CSH2_k127_5325988_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000009257 115.0
CSH2_k127_5325988_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000006067 91.0
CSH2_k127_5325988_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000001004 63.0
CSH2_k127_5325988_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000006057 49.0
CSH2_k127_5335306_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002502 233.0
CSH2_k127_5335306_1 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000003064 218.0
CSH2_k127_5340429_0 PFAM Ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 8.277e-204 640.0
CSH2_k127_5340429_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 398.0
CSH2_k127_5340429_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000001475 84.0
CSH2_k127_5340429_3 ATP:ADP antiporter activity - - - 0.00000000004931 74.0
CSH2_k127_5342775_0 Tfp pilus assembly protein FimV - - - 0.00000000000000000000003714 115.0
CSH2_k127_5356103_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 393.0
CSH2_k127_5356103_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000654 210.0
CSH2_k127_5370718_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 619.0
CSH2_k127_5370718_1 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 372.0
CSH2_k127_5370718_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 299.0
CSH2_k127_5372423_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1773.0
CSH2_k127_5372423_2 N-4 methylation of cytosine K00571,K03497 - 2.1.1.72 0.00000001528 55.0
CSH2_k127_5373652_0 - - - - 0.000000000000000000000000000000000000054 144.0
CSH2_k127_5373652_1 PFAM peptidase M55 D-aminopeptidase K16203 - - 0.0000000000004723 79.0
CSH2_k127_5373652_2 Sir2 family K12410 - - 0.00008775 46.0
CSH2_k127_5386684_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000009869 150.0
CSH2_k127_5386684_1 - - - - 0.00000000000000000001267 93.0
CSH2_k127_5386684_2 DNA repair exonuclease K03547 - - 0.0000000000007893 80.0
CSH2_k127_5386684_3 AAA domain - - - 0.000001253 62.0
CSH2_k127_5386684_4 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000007515 57.0
CSH2_k127_5389228_0 UPF0210 protein K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 375.0
CSH2_k127_5389228_1 Omptin family - - - 0.000001676 54.0
CSH2_k127_5394885_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07711,K19694 - 2.7.13.3 0.000000000000000000000000000000000000000000000000009674 196.0
CSH2_k127_5394885_1 Kelch motif - - - 0.0000002203 57.0
CSH2_k127_542702_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 402.0
CSH2_k127_542702_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000003314 181.0
CSH2_k127_5434559_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 605.0
CSH2_k127_5434559_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001323 262.0
CSH2_k127_5434559_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000005326 184.0
CSH2_k127_5434559_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000683 178.0
CSH2_k127_5434559_4 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000001782 105.0
CSH2_k127_5434559_5 Peptidase family S51 - - - 0.00000000000000002669 91.0
CSH2_k127_5434559_6 Cell wall hydrolase autolysin - - - 0.00000000000000003513 88.0
CSH2_k127_5434559_7 PBS lyase HEAT domain protein repeat-containing protein K22221 - - 0.0000000000001339 83.0
CSH2_k127_5434559_8 Bacterial regulatory proteins, tetR family - - - 0.00000000008465 70.0
CSH2_k127_5434559_9 HD domain protein - - - 0.0000000007944 60.0
CSH2_k127_5443714_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1011.0
CSH2_k127_5443714_1 AMP-binding enzyme C-terminal domain - - - 2.202e-278 861.0
CSH2_k127_5443714_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 349.0
CSH2_k127_5443714_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 318.0
CSH2_k127_5443714_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000003475 239.0
CSH2_k127_5443714_5 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000001426 216.0
CSH2_k127_5443714_6 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000001835 205.0
CSH2_k127_5444457_0 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001145 252.0
CSH2_k127_5444457_1 cell redox homeostasis K02199,K03671 - - 0.0000000000000000000000000000000000007085 145.0
CSH2_k127_5444457_2 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000002723 100.0
CSH2_k127_5494642_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 346.0
CSH2_k127_5494642_1 tetratricopeptide repeat - - - 0.000000000000181 83.0
CSH2_k127_5511239_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 1.871e-223 706.0
CSH2_k127_5511239_1 PFAM HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009945 282.0
CSH2_k127_5511239_2 PFAM Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000004808 164.0
CSH2_k127_5543304_0 ompA family - - - 0.000000000000000000000000000000002311 143.0
CSH2_k127_5543304_1 Belongs to the ompA family - - - 0.0000000000000000000001025 111.0
CSH2_k127_5565399_0 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 578.0
CSH2_k127_5565399_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 314.0
CSH2_k127_5565399_2 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001939 276.0
CSH2_k127_5565399_3 PFAM ATP-binding region, ATPase domain protein K17752 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000002753 248.0
CSH2_k127_5565399_4 Hypothetical methyltransferase - - - 0.000000002518 67.0
CSH2_k127_5569822_0 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000003033 231.0
CSH2_k127_5569822_1 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000003675 154.0
CSH2_k127_5571584_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 497.0
CSH2_k127_5584250_0 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 423.0
CSH2_k127_5584250_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 296.0
CSH2_k127_5584250_2 - - - - 0.000000000000000000000000000000000000000000000000000000000006739 222.0
CSH2_k127_5584250_3 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000006573 159.0
CSH2_k127_5586468_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 477.0
CSH2_k127_5586468_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001834 243.0
CSH2_k127_5600301_0 regulation of response to stimulus K01126,K21449 - 3.1.4.46 0.000001181 53.0
CSH2_k127_5600301_1 RNA polymerase sigma-70 factor K03088 - - 0.0002559 46.0
CSH2_k127_5603542_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 533.0
CSH2_k127_5603542_1 PFAM pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000005722 183.0
CSH2_k127_5603542_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000001343 174.0
CSH2_k127_5603542_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000002204 145.0
CSH2_k127_5603542_4 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00002133 50.0
CSH2_k127_5614826_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 331.0
CSH2_k127_5614826_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003261 276.0
CSH2_k127_5614826_2 negative regulation of transcription, DNA-templated - - - 0.00000000004596 69.0
CSH2_k127_5614826_3 Alpha/beta hydrolase family K06889 - - 0.00002068 48.0
CSH2_k127_5637618_0 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 351.0
CSH2_k127_5637618_1 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000006052 185.0
CSH2_k127_5637618_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000003608 117.0
CSH2_k127_5658779_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.456e-255 799.0
CSH2_k127_5658779_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 524.0
CSH2_k127_5658779_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 318.0
CSH2_k127_5658779_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000007116 238.0
CSH2_k127_5658779_4 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000002876 203.0
CSH2_k127_5658779_5 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000001513 158.0
CSH2_k127_5658859_0 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 507.0
CSH2_k127_5658859_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.0000000000000000002157 97.0
CSH2_k127_56720_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 499.0
CSH2_k127_56720_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 365.0
CSH2_k127_56720_2 PFAM Methyltransferase type K15256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002704 251.0
CSH2_k127_5675280_0 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 587.0
CSH2_k127_5675280_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 482.0
CSH2_k127_5675280_2 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 289.0
CSH2_k127_5675280_3 PilZ domain - - - 0.00000000148 63.0
CSH2_k127_5675280_4 unfolded protein binding. It is involved in the biological process described with protein folding K09507,K09510,K09511 GO:0000122,GO:0001671,GO:0002682,GO:0002684,GO:0003674,GO:0003712,GO:0003714,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006357,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008047,GO:0008134,GO:0008150,GO:0008593,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0014069,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0023051,GO:0023057,GO:0030234,GO:0030425,GO:0030544,GO:0031072,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031647,GO:0031974,GO:0031981,GO:0032279,GO:0032781,GO:0033554,GO:0035966,GO:0036477,GO:0042221,GO:0042689,GO:0042691,GO:0042995,GO:0043005,GO:0043025,GO:0043085,GO:0043197,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043462,GO:0043618,GO:0043620,GO:0044087,GO:0044093,GO:0044297,GO:0044309,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0045595,GO:0045597,GO:0045610,GO:0045612,GO:0045746,GO:0045892,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050821,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051094,GO:0051117,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051239,GO:0051252,GO:0051253,GO:0051336,GO:0051345,GO:0051716,GO:0060255,GO:0060589,GO:0060590,GO:0061077,GO:0061827,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0090083,GO:0090084,GO:0097201,GO:0097223,GO:0097447,GO:0097458,GO:0098772,GO:0098794,GO:0098984,GO:0099522,GO:0099524,GO:0099572,GO:0120025,GO:0120038,GO:0140110,GO:1900034,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000101 54.0
CSH2_k127_5687698_0 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004657 270.0
CSH2_k127_5687698_1 histidine kinase A domain protein - - - 0.00000006352 66.0
CSH2_k127_5693520_0 epimerase dehydratase family K01784,K08679 - 5.1.3.2,5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 520.0
CSH2_k127_5693520_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 486.0
CSH2_k127_5695105_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.894e-285 896.0
CSH2_k127_5695105_1 PFAM Late competence development protein ComFB K02241 - - 0.000000000000000000001431 103.0
CSH2_k127_5720399_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 393.0
CSH2_k127_5720399_1 Peptidase, M23 - - - 0.0000000000000000000000000000000000000000000000000006114 196.0
CSH2_k127_5729473_0 SprA protein - - - 0.00000000004412 76.0
CSH2_k127_5729568_0 Belongs to the GPI family K01810 - 5.3.1.9 2.615e-273 849.0
CSH2_k127_5729568_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000008006 219.0
CSH2_k127_5729568_2 PFAM thioesterase superfamily K02614 - - 0.00000000000000000000003038 104.0
CSH2_k127_5729568_3 - - - - 0.0000000000004897 76.0
CSH2_k127_5733214_0 TrkA-N domain K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 319.0
CSH2_k127_5733214_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000001736 159.0
CSH2_k127_5733356_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 8.39e-222 696.0
CSH2_k127_5733356_1 regulation of circadian rhythm K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007146 261.0
CSH2_k127_5734177_0 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000003879 183.0
CSH2_k127_5734177_1 Permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000001437 167.0
CSH2_k127_5747601_0 AAA ATPase domain - - - 0.0 1190.0
CSH2_k127_5747601_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 498.0
CSH2_k127_5747601_2 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000005297 157.0
CSH2_k127_5753624_0 translation elongation factor activity K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000003724 196.0
CSH2_k127_5753624_1 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.0000000000000000000000000000000005625 136.0
CSH2_k127_5753624_2 PFAM Sporulation and spore germination - - - 0.00000000002173 66.0
CSH2_k127_5756743_0 HIT domain - - - 0.0000000000000000000000000000000000000000005575 162.0
CSH2_k127_5756743_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000006171 118.0
CSH2_k127_5756743_2 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000009235 109.0
CSH2_k127_5756743_3 Domain of unknown function (DUF4115) - - - 0.00007244 48.0
CSH2_k127_5764613_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000007691 256.0
CSH2_k127_5764613_1 - - - - 0.00000001042 58.0
CSH2_k127_5767256_0 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001021 276.0
CSH2_k127_5767256_1 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - 0.0000000000000000000000000000000000000000000000000000000000000003361 227.0
CSH2_k127_5767256_2 AAA domain K03546 - - 0.000000000000000000000000000000000000000000000000000000002161 207.0
CSH2_k127_5767256_3 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000004357 207.0
CSH2_k127_5767256_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000001249 85.0
CSH2_k127_5767256_5 PFAM Methyltransferase type 11 - - - 0.0008446 50.0
CSH2_k127_577899_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000003999 90.0
CSH2_k127_5788470_0 Belongs to the ClpX chaperone family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 466.0
CSH2_k127_5788470_1 Thioesterase superfamily - - - 0.000000000000000000001012 99.0
CSH2_k127_5788470_2 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000004353 59.0
CSH2_k127_5788470_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000001262 56.0
CSH2_k127_5806416_0 metallo-beta-lactamase K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 518.0
CSH2_k127_5806416_1 PFAM Methyltransferase type 11 K03892 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006371 250.0
CSH2_k127_5809881_0 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000001693 150.0
CSH2_k127_5809881_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000006367 146.0
CSH2_k127_5809881_2 acid phosphatase activity - - - 0.00004244 52.0
CSH2_k127_5816383_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 9.548e-219 688.0
CSH2_k127_581723_0 GHKL domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000007407 283.0
CSH2_k127_5825400_0 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000008399 218.0
CSH2_k127_5825400_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000001719 155.0
CSH2_k127_5825400_2 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000009414 53.0
CSH2_k127_5828237_0 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 298.0
CSH2_k127_5828237_1 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000003244 174.0
CSH2_k127_5828237_2 PFAM CheC domain protein K03409 - - 0.0000000000000000000006756 101.0
CSH2_k127_584788_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000005803 183.0
CSH2_k127_5850971_0 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 303.0
CSH2_k127_5850971_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000002356 125.0
CSH2_k127_5854972_0 Penicillin-binding protein 1A K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000001868 160.0
CSH2_k127_5854972_1 heme binding K08642 - - 0.00000000000000000000000000002619 128.0
CSH2_k127_5855253_0 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000005402 207.0
CSH2_k127_5856348_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000005251 147.0
CSH2_k127_5856348_1 MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000009808 147.0
CSH2_k127_5856348_2 DNA topoisomerase (ATP-hydrolyzing) inhibitor activity K13652 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000006245 88.0
CSH2_k127_5856630_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 471.0
CSH2_k127_5856630_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 382.0
CSH2_k127_5856630_2 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 301.0
CSH2_k127_5856630_3 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000004062 80.0
CSH2_k127_5860087_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.457e-204 645.0
CSH2_k127_5860087_1 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 481.0
CSH2_k127_5860087_2 - - - - 0.000000000000000000000000000000000000000000000000002032 192.0
CSH2_k127_5860087_3 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000003251 149.0
CSH2_k127_5860087_4 Binds the 23S rRNA K02909 - - 0.0000000000000000000000003917 107.0
CSH2_k127_5860087_5 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.00000000000000005834 92.0
CSH2_k127_5860087_6 lipid-A-disaccharide synthase activity K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000003018 65.0
CSH2_k127_5866695_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 334.0
CSH2_k127_5866695_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000168 202.0
CSH2_k127_5866695_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000001099 145.0
CSH2_k127_5866695_3 protein trimerization K01999,K08309 - - 0.000000000001144 78.0
CSH2_k127_5869841_0 Radical SAM K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 318.0
CSH2_k127_5869841_1 Histidine kinase - - - 0.00000000000000000000000000003902 129.0
CSH2_k127_5887768_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 514.0
CSH2_k127_5887768_1 methyltransferase - - - 0.000000000000000000000000000000000000000000003402 168.0
CSH2_k127_5894723_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 2.533e-196 635.0
CSH2_k127_5894723_1 Flagellar hook protein flgE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 460.0
CSH2_k127_5894723_2 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000001141 126.0
CSH2_k127_5894723_3 Flagellar hook capping protein - N-terminal region K02389 - - 0.000000000000000000003672 100.0
CSH2_k127_5894723_4 Flagellar hook-length control protein FliK K02414 - - 0.00013 54.0
CSH2_k127_5899884_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 297.0
CSH2_k127_5899884_1 Protein of unknown function DUF115 - - - 0.000000000000003199 82.0
CSH2_k127_5907981_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 556.0
CSH2_k127_5907981_1 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000000008388 172.0
CSH2_k127_5907981_2 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.0000000147 63.0
CSH2_k127_5909229_0 AMP-binding enzyme C-terminal domain - - - 7.308e-281 869.0
CSH2_k127_5909229_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 8.437e-269 839.0
CSH2_k127_5909229_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005972 272.0
CSH2_k127_5912396_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.646e-242 772.0
CSH2_k127_5912396_1 Outer membrane efflux protein - - - 0.000000000001875 77.0
CSH2_k127_591648_0 PFAM ABC transporter K06158 - - 1.63e-242 764.0
CSH2_k127_591648_1 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 415.0
CSH2_k127_591648_2 Peptidase M16C associated K06972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 406.0
CSH2_k127_591869_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 394.0
CSH2_k127_591869_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000008283 236.0
CSH2_k127_591869_2 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.0000000000000000000000000000000000000000000000002475 199.0
CSH2_k127_591869_4 PFAM response regulator receiver - - - 0.000000001887 71.0
CSH2_k127_591869_5 PAS domain containing protein - - - 0.0000007776 63.0
CSH2_k127_5928767_0 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000001301 126.0
CSH2_k127_5928767_1 tetratricopeptide repeat - - - 0.000002671 59.0
CSH2_k127_5930629_0 Riboflavin synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000001701 198.0
CSH2_k127_5930629_1 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000002583 177.0
CSH2_k127_5930629_2 Ankyrin repeats (3 copies) K21440 - - 0.000000000000000000000000000000001473 141.0
CSH2_k127_5930629_3 Ankyrin repeat K21440 - - 0.0000000000003316 71.0
CSH2_k127_5930629_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000002227 70.0
CSH2_k127_5931690_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001047 275.0
CSH2_k127_5931690_1 ThiS family K03154 - - 0.000000002929 60.0
CSH2_k127_5931690_2 Staphylococcal nuclease homologues K00590,K01174 - 2.1.1.113,3.1.31.1 0.00000161 56.0
CSH2_k127_5933130_0 AAA domain K03546 - - 0.0000000000000000000000000000000000000000000000000001641 200.0
CSH2_k127_5933130_1 DNA repair exonuclease K03547 - - 0.000000000008741 69.0
CSH2_k127_594074_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 3.918e-291 901.0
CSH2_k127_594074_1 Radical SAM N-terminal - - - 6.397e-228 717.0
CSH2_k127_594074_2 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 520.0
CSH2_k127_594074_3 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 479.0
CSH2_k127_594074_4 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 307.0
CSH2_k127_594074_5 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties - - - 0.00007088 48.0
CSH2_k127_5943340_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006456 276.0
CSH2_k127_5943340_1 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000324 117.0
CSH2_k127_5943340_2 Outer membrane protein beta-barrel domain K07275 - - 0.0000000674 61.0
CSH2_k127_5951546_0 CoA-substrate-specific enzyme activase - - - 0.0 1894.0
CSH2_k127_5951546_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.117e-216 679.0
CSH2_k127_5951546_2 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000003265 210.0
CSH2_k127_5951546_3 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000008939 162.0
CSH2_k127_596853_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 4.885e-201 641.0
CSH2_k127_5973955_0 - - - - 0.0000000000000000000000000000000000000001634 164.0
CSH2_k127_5973955_1 Cyclic nucleotide binding domain protein - - - 0.0000000000000000000000000000000002202 138.0
CSH2_k127_5973955_2 TrkA-N domain K10716 - - 0.0000000000000000004806 89.0
CSH2_k127_5973955_3 Nudix N-terminal - - - 0.000000000005649 73.0
CSH2_k127_598664_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 574.0
CSH2_k127_598664_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 320.0
CSH2_k127_5991018_0 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000004277 218.0
CSH2_k127_5991018_1 lipoprotein localization to outer membrane K02004,K09808 - - 0.000000000000000000000000000000000000000000000000000000009162 211.0
CSH2_k127_5991018_2 PFAM Xanthine uracil vitamin C permease K06901 - - 0.00000000000000000000000000003715 119.0
CSH2_k127_5991887_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000001917 207.0
CSH2_k127_5991887_1 PFAM histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000004425 134.0
CSH2_k127_5991887_2 Permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000001842 128.0
CSH2_k127_5991887_3 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.000000000000000000006024 96.0
CSH2_k127_5992871_0 TPR Domain containing protein K12600 - - 0.00000000000000000000000000000000000000000000001044 186.0
CSH2_k127_5992871_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000000000000000000000000003053 144.0
CSH2_k127_6000141_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 339.0
CSH2_k127_6000141_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000002616 189.0
CSH2_k127_6002239_0 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 375.0
CSH2_k127_6002239_1 PFAM Transglycosylase-associated protein - - - 0.000000000000000000000002608 104.0
CSH2_k127_6002239_2 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000001188 67.0
CSH2_k127_6005943_0 Adenylate guanylate cyclase catalytic domain protein K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 342.0
CSH2_k127_6006228_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002235 233.0
CSH2_k127_6006228_1 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000002522 203.0
CSH2_k127_6006228_2 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.000000000000000000000000000000000000000000006421 173.0
CSH2_k127_6014123_0 Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 372.0
CSH2_k127_6014123_1 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000005847 170.0
CSH2_k127_6014123_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07713,K07714,K10943 - - 0.0000000000000003032 91.0
CSH2_k127_6014123_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000002549 78.0
CSH2_k127_6017914_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 1.276e-235 735.0
CSH2_k127_6017914_1 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 366.0
CSH2_k127_6018687_0 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 508.0
CSH2_k127_6018687_1 SMART Elongator protein 3 MiaB NifB K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001 287.0
CSH2_k127_6018687_2 PFAM MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006243 248.0
CSH2_k127_6018687_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009566 238.0
CSH2_k127_6018687_4 Flagellar motor protein K02557 - - 0.00000000000000000000000000000000000000000001759 171.0
CSH2_k127_6018687_5 GtrA-like protein K00995 - 2.7.8.5 0.0000000000000000000000000002926 124.0
CSH2_k127_6018687_6 DUF218 domain - - - 0.000000000000000000000000001452 117.0
CSH2_k127_6018687_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0003243 52.0
CSH2_k127_6026512_0 Single Cache domain 2 K02480 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000005407 218.0
CSH2_k127_6074993_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005253 265.0
CSH2_k127_6074993_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000001839 70.0
CSH2_k127_6074993_2 peptidyl-tyrosine sulfation - - - 0.00008852 54.0
CSH2_k127_6076677_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 377.0
CSH2_k127_6076677_1 His Kinase A (phosphoacceptor) domain - - - 0.000001149 50.0
CSH2_k127_6084227_2 - - - - 0.000007103 54.0
CSH2_k127_6089283_0 ATP hydrolysis coupled proton transport K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 355.0
CSH2_k127_6091752_0 Domain of unknown function (DUF4389) - - - 0.000008508 59.0
CSH2_k127_6094763_0 - - - - 0.0000000000000000000000000000000000000000000000000000000006048 210.0
CSH2_k127_6094763_1 GGDEF domain - - - 0.0000878 55.0
CSH2_k127_6120522_0 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 321.0
CSH2_k127_6120522_1 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000004078 172.0
CSH2_k127_6126320_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000005517 248.0
CSH2_k127_6126320_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000004206 238.0
CSH2_k127_6140816_0 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000006871 195.0
CSH2_k127_6140816_2 Putative zinc-finger - - - 0.00000003749 63.0
CSH2_k127_6142876_0 glycosyl transferase group 1 K21011 - - 0.00000000000003585 74.0
CSH2_k127_6142876_1 GAF domain K21009 - - 0.0000000052 65.0
CSH2_k127_6142876_2 chaperone-mediated protein folding K09809,K21010 - 2.7.8.12 0.000003952 58.0
CSH2_k127_6143436_0 Respiratory-chain NADH dehydrogenase 51 Kd subunit K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 4.322e-238 750.0
CSH2_k127_6143436_1 Molybdopterin oxidoreductase Fe4S4 domain K00123,K05299 - 1.17.1.10,1.17.1.9 2.61e-224 706.0
CSH2_k127_6143436_2 Molybdopterin oxidoreductase Fe4S4 domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 519.0
CSH2_k127_6143436_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000005476 180.0
CSH2_k127_6143436_4 Peptidoglycan-synthase activator LpoB - - - 0.00000000000000001201 93.0
CSH2_k127_6143436_5 Major facilitator superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000007604 68.0
CSH2_k127_6145165_0 tetratricopeptide repeat - - - 0.00006975 56.0
CSH2_k127_6147989_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002487 284.0
CSH2_k127_6147989_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000001951 229.0
CSH2_k127_6147989_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000002646 80.0
CSH2_k127_6148126_0 Biotin and Thiamin Synthesis associated K03150 - 4.1.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 439.0
CSH2_k127_6151841_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 608.0
CSH2_k127_6151841_1 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000005792 197.0
CSH2_k127_6152491_0 CoA-substrate-specific enzyme activase - - - 5.851e-265 843.0
CSH2_k127_6156962_0 Methyltransferase domain - - - 0.00000000000000000000000000000000006281 142.0
CSH2_k127_6156962_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000002154 98.0
CSH2_k127_6156962_2 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000003887 72.0
CSH2_k127_6156962_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00001016 52.0
CSH2_k127_6158176_0 aldolase class II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 559.0
CSH2_k127_6158176_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000002461 122.0
CSH2_k127_6158176_2 - - - - 0.00000000000000000000133 96.0
CSH2_k127_6158176_5 - - - - 0.0000001618 57.0
CSH2_k127_6161174_0 A-macroglobulin complement component - - - 0.000000000000000000000000000000000000000000000000000009445 216.0
CSH2_k127_6165712_0 Domain of unknown function (DUF3492) K21011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001178 273.0
CSH2_k127_6165712_1 Putative exopolysaccharide Exporter (EPS-E) K21012 - - 0.00000000000000000000000000008481 126.0
CSH2_k127_6174796_0 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 524.0
CSH2_k127_6174796_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000001429 192.0
CSH2_k127_6174796_2 adenosylhomocysteine nucleosidase activity K01243 - 3.2.2.9 0.000000000000000000000000000000000000000002611 162.0
CSH2_k127_6174796_3 HD domain - - - 0.0000000000000000000000000000000000001737 156.0
CSH2_k127_6174796_4 - - - - 0.00000000000009308 76.0
CSH2_k127_6174969_0 aerobic electron transport chain K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 431.0
CSH2_k127_6174969_1 Belongs to the aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000001393 268.0
CSH2_k127_6174969_2 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000005185 272.0
CSH2_k127_6174969_3 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000004456 146.0
CSH2_k127_6174969_4 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000006361 48.0
CSH2_k127_6176008_0 PFAM transferase hexapeptide repeat containing protein K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 403.0
CSH2_k127_6176008_1 regulation of ryanodine-sensitive calcium-release channel activity - - - 0.00000000000000000000000000000000000000000197 162.0
CSH2_k127_6176008_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000001926 80.0
CSH2_k127_6176008_3 oxidoreductase activity K00505 - 1.14.18.1 0.0000000004163 70.0
CSH2_k127_6187445_0 Paraquat-inducible protein A - - - 0.00000000000000000000000000000000000000000002329 172.0
CSH2_k127_6187445_1 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000002837 157.0
CSH2_k127_6187805_0 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 571.0
CSH2_k127_6187805_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001722 247.0
CSH2_k127_6187805_2 - - - - 0.00000000000000000000000000000000000000000000000001895 181.0
CSH2_k127_6194547_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 331.0
CSH2_k127_6194547_1 helix_turn_helix, Arsenical Resistance Operon Repressor K03655,K03892 - 3.6.4.12 0.00000000000000000000000000000000005546 136.0
CSH2_k127_6194547_2 helix_turn_helix gluconate operon transcriptional repressor - - - 0.0000000005243 66.0
CSH2_k127_6212270_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 477.0
CSH2_k127_6212270_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000001052 183.0
CSH2_k127_6212270_2 Membrane-associated sensor domain - - - 0.0000000000000000000000000000000009042 151.0
CSH2_k127_6214607_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 411.0
CSH2_k127_6214607_1 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.000000124 59.0
CSH2_k127_6214617_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 388.0
CSH2_k127_6214617_1 pyruvate phosphate dikinase, PEP K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 295.0
CSH2_k127_6214617_2 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000004631 228.0
CSH2_k127_6236665_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 589.0
CSH2_k127_6236665_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 504.0
CSH2_k127_6236665_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 387.0
CSH2_k127_6249019_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 617.0
CSH2_k127_6249019_1 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000003019 67.0
CSH2_k127_6288810_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000874 220.0
CSH2_k127_6288810_1 Protein of unknown function (DUF501) K09009 - - 0.00000000000000000000005338 105.0
CSH2_k127_6291928_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000001083 248.0
CSH2_k127_6291928_1 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000001971 224.0
CSH2_k127_6291928_2 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain K02030 - - 0.00000000000000000000000000000006228 135.0
CSH2_k127_6291928_3 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain K02030 - - 0.00000000000000000000000000001985 127.0
CSH2_k127_6304009_0 ABC-type amino acid transport signal transduction systems, periplasmic component domain K02030 - - 0.00000000000000000000000000000000001749 144.0
CSH2_k127_6304009_1 Exodeoxyribonuclease V, gamma subunit K03583 - 3.1.11.5 0.000000000000000000000000000003195 126.0
CSH2_k127_6304152_0 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 407.0
CSH2_k127_6304152_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000009293 120.0
CSH2_k127_6333397_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 571.0
CSH2_k127_6333397_1 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000003521 247.0
CSH2_k127_6333397_2 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000002771 145.0
CSH2_k127_6333961_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 326.0
CSH2_k127_6333961_1 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000002056 167.0
CSH2_k127_6333961_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000001516 139.0
CSH2_k127_6341851_0 photoreceptor activity K02007,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 320.0
CSH2_k127_6341851_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000005813 199.0
CSH2_k127_6341929_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000004458 200.0
CSH2_k127_6341929_1 Calcineurin-like phosphoesterase - - - 0.0000000001515 72.0
CSH2_k127_634376_0 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000004656 118.0
CSH2_k127_634376_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000736 88.0
CSH2_k127_634376_2 Hsp20/alpha crystallin family K13993 - - 0.0000000000000001057 85.0
CSH2_k127_634376_3 Cyclic-nucleotide-gated cation channel K04949,K04950 GO:0003674,GO:0005215,GO:0005216,GO:0005217,GO:0005221,GO:0005244,GO:0005249,GO:0005261,GO:0005267,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0007154,GO:0007165,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015276,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0017071,GO:0019932,GO:0019935,GO:0022803,GO:0022832,GO:0022834,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0023052,GO:0030001,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034702,GO:0034703,GO:0035556,GO:0042391,GO:0043855,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099094,GO:1902495,GO:1990351 - 0.00000218 58.0
CSH2_k127_6367821_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 440.0
CSH2_k127_6367821_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000001649 190.0
CSH2_k127_6367821_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000006891 99.0
CSH2_k127_6367821_3 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000002205 69.0
CSH2_k127_6367821_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000001226 54.0
CSH2_k127_6369926_0 Parallel beta-helix repeats - - - 0.00000000006573 68.0
CSH2_k127_6369926_1 sidekick-2 K16353 GO:0001654,GO:0001745,GO:0001754,GO:0003407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007155,GO:0007156,GO:0007275,GO:0007399,GO:0007416,GO:0007423,GO:0008150,GO:0009653,GO:0009887,GO:0009987,GO:0010721,GO:0010842,GO:0016020,GO:0016021,GO:0016043,GO:0022008,GO:0022607,GO:0022610,GO:0030154,GO:0030182,GO:0031224,GO:0031226,GO:0032501,GO:0032502,GO:0034330,GO:0042675,GO:0042802,GO:0043010,GO:0043473,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045202,GO:0045216,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0046530,GO:0046532,GO:0046533,GO:0048066,GO:0048513,GO:0048519,GO:0048523,GO:0048592,GO:0048593,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0050808,GO:0050931,GO:0051093,GO:0051239,GO:0051241,GO:0051960,GO:0051961,GO:0060041,GO:0060042,GO:0060219,GO:0060284,GO:0065007,GO:0071840,GO:0071944,GO:0090596,GO:0098609,GO:0098742,GO:2000026 - 0.0009462 51.0
CSH2_k127_6380361_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.465e-271 858.0
CSH2_k127_6380361_1 Stage II sporulation protein E (SpoIIE) - - - 0.000000000000000000000000000000216 131.0
CSH2_k127_6388019_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003799 256.0
CSH2_k127_6388019_1 protein histidine kinase activity K21022 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000227 228.0
CSH2_k127_6388019_2 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000399 185.0
CSH2_k127_6388019_3 PFAM Signal transduction response regulator, receiver domain - - - 0.00000000000000000000000000000000000000000000000008229 181.0
CSH2_k127_6388019_4 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000004084 160.0
CSH2_k127_6388019_5 membrane - - - 0.00002742 54.0
CSH2_k127_639934_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 407.0
CSH2_k127_639934_1 UPF0210 protein K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 396.0
CSH2_k127_639934_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 314.0
CSH2_k127_639934_3 Belongs to the UPF0237 family K07166 - - 0.000000000000000000003122 96.0
CSH2_k127_639934_4 PFAM ABC transporter K01990 - - 0.00000005049 54.0
CSH2_k127_6399953_0 protein secretion by the type III secretion system K02412,K03224 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 384.0
CSH2_k127_6399953_1 Transglycosylase SLT domain - - - 0.0000000000000000000000000000002653 130.0
CSH2_k127_6399953_2 flagellar export protein FliJ K02413 - - 0.0003282 49.0
CSH2_k127_6412081_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 7.526e-293 901.0
CSH2_k127_6412081_1 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 468.0
CSH2_k127_6412081_2 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 386.0
CSH2_k127_6412081_3 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000000006821 119.0
CSH2_k127_6412081_4 Encoded by K17560 - - 0.0000000006307 72.0
CSH2_k127_6412081_5 - - - - 0.0000000696 59.0
CSH2_k127_6412081_6 type IV pilus assembly PilZ - - - 0.0002146 48.0
CSH2_k127_6430304_0 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004828 256.0
CSH2_k127_6430304_1 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000000000000000000000000000000000000002028 223.0
CSH2_k127_6430304_2 binding domain protein - - - 0.00000000000000000000000000001812 129.0
CSH2_k127_6432415_0 Uncharacterised MFS-type transporter YbfB - - - 3.759e-221 691.0
CSH2_k127_6432415_1 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.00000000000000000000000000000000000005158 151.0
CSH2_k127_6432415_2 methyltransferase activity K21377 - 2.1.1.302 0.0000000000001134 74.0
CSH2_k127_6458393_0 acyl-coa dehydrogenase K09456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 356.0
CSH2_k127_6458393_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000001402 243.0
CSH2_k127_6458393_2 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000004536 177.0
CSH2_k127_6458393_3 chemotaxis protein K03406 - - 0.000000000000000000000001052 120.0
CSH2_k127_6458461_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 467.0
CSH2_k127_6458461_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 355.0
CSH2_k127_6458461_2 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000004557 152.0
CSH2_k127_6499374_0 - - - - 0.0000000000000000000000000000000000000000000000000000000005812 208.0
CSH2_k127_6499374_1 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000001339 213.0
CSH2_k127_6541228_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 432.0
CSH2_k127_6541228_1 CarD-like/TRCF domain K07736 - - 0.0000000000000000007902 87.0
CSH2_k127_6557904_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.049e-271 850.0
CSH2_k127_6557904_1 Acyl-CoA dehydrogenase, middle domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 302.0
CSH2_k127_6557904_2 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000005162 168.0
CSH2_k127_6557904_3 TIGRFAM Protein of - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000103 113.0
CSH2_k127_6557904_4 Repeated motif present between transmembrane helices in cystinosin, yeast ERS1p, mannose-P-dolichol utilization defect 1, and other hypothetical proteins. K15383 - - 0.00001427 48.0
CSH2_k127_6562947_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 2.381e-265 830.0
CSH2_k127_6562947_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.868e-221 699.0
CSH2_k127_6562947_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 9.956e-199 636.0
CSH2_k127_6562947_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000001197 217.0
CSH2_k127_6562947_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000001659 185.0
CSH2_k127_6562947_5 Psort location Cytoplasmic, score 8.96 - - - 0.00001182 53.0
CSH2_k127_6570708_0 3'-5' exonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004161 270.0
CSH2_k127_6570708_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000002287 66.0
CSH2_k127_6581574_0 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 314.0
CSH2_k127_6581574_1 Mo-molybdopterin cofactor metabolic process K03636,K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002878 251.0
CSH2_k127_6581574_2 flagellar motor switch protein K02410 - - 0.00000000000000000000000000000000000000000000000000000003439 209.0
CSH2_k127_6581574_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000364 187.0
CSH2_k127_6581574_4 Transglycosylase SLT domain - - - 0.000000000000000000000000000002049 128.0
CSH2_k127_6581574_5 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000008026 84.0
CSH2_k127_6581574_6 domain protein - - - 0.0000000005123 68.0
CSH2_k127_6581574_7 transmembrane transport - - - 0.0000000007539 64.0
CSH2_k127_6581574_8 Zinc ribbon domain K07164 - - 0.0000001289 62.0
CSH2_k127_6597095_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000003602 237.0
CSH2_k127_6597095_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.0000000000001245 70.0
CSH2_k127_6597095_2 PFAM Family of K09800 - - 0.000001092 62.0
CSH2_k127_6605558_0 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 462.0
CSH2_k127_6605558_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 301.0
CSH2_k127_6605558_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003406 297.0
CSH2_k127_6605558_3 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000001383 234.0
CSH2_k127_6645471_0 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate K00991,K21030 - 2.7.7.40,2.7.7.60 0.0000000000000000000000000000000000000000000000000004023 192.0
CSH2_k127_6645471_1 Sugar (and other) transporter K08196 - - 0.0000000000000000000000008273 117.0
CSH2_k127_6668842_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000008903 222.0
CSH2_k127_6668842_1 tigr00255 - - - 0.00000000000000000000000000000000000000000003057 172.0
CSH2_k127_6668842_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000001475 154.0
CSH2_k127_6668842_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000005046 123.0
CSH2_k127_6668842_4 Belongs to the UPF0296 family K09777 - - 0.00000000000000000000000009439 108.0
CSH2_k127_6671406_0 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000004354 134.0
CSH2_k127_6671406_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0002279 49.0
CSH2_k127_66901_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 6.044e-212 672.0
CSH2_k127_66901_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 402.0
CSH2_k127_66901_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 363.0
CSH2_k127_66901_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000005309 89.0
CSH2_k127_6693098_0 Domain of unknown function (DUF3943) - - - 0.00000000000003539 84.0
CSH2_k127_6707672_0 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 486.0
CSH2_k127_6707672_1 peptidase - - - 0.000000000000000000000000000007115 132.0
CSH2_k127_6707672_3 Bacterial transferase hexapeptide (six repeats) - - - 0.0007844 42.0
CSH2_k127_6713322_0 aconitate hydratase K01681 - 4.2.1.3 1.212e-259 814.0
CSH2_k127_6713322_1 C-terminal, D2-small domain, of ClpB protein K03694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 426.0
CSH2_k127_6713322_2 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 331.0
CSH2_k127_6713322_3 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000002169 190.0
CSH2_k127_6713322_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000002352 144.0
CSH2_k127_6713322_5 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000004901 114.0
CSH2_k127_6713322_6 histone H2A K63-linked ubiquitination K01768,K21397 - 4.6.1.1 0.000000002886 62.0
CSH2_k127_6713322_7 COG0840 Methyl-accepting chemotaxis protein - - - 0.00002276 57.0
CSH2_k127_6724348_0 PFAM Cyclic nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000001024 195.0
CSH2_k127_6724348_1 Methyltransferase type 11 - - - 0.0000000000000000000000000000000001024 141.0
CSH2_k127_6724348_2 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.0000000000000000000000000000006774 129.0
CSH2_k127_6724348_3 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000000000000000000000103 113.0
CSH2_k127_6733642_0 phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000006385 196.0
CSH2_k127_6733642_1 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000007801 132.0
CSH2_k127_6733642_2 SMART Cold shock protein K03704 - - 0.00000000000000000001124 94.0
CSH2_k127_6733642_3 Psort location CytoplasmicMembrane, score K19302 - 3.6.1.27 0.000000000003508 74.0
CSH2_k127_6734326_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 8.056e-269 844.0
CSH2_k127_6734326_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 1.23e-268 850.0
CSH2_k127_6734326_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 603.0
CSH2_k127_6734326_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000002317 221.0
CSH2_k127_6734326_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000003037 214.0
CSH2_k127_6734326_5 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000568 150.0
CSH2_k127_6737630_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 6.497e-203 643.0
CSH2_k127_6737630_1 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.000000000000000000000000000000001289 139.0
CSH2_k127_6744740_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 329.0
CSH2_k127_6744740_1 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000792 261.0
CSH2_k127_6744740_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000004554 182.0
CSH2_k127_6747140_0 phosphoesterase RecJ domain protein - - - 0.0000000000000000000000000001516 128.0
CSH2_k127_6747140_1 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000002432 68.0
CSH2_k127_6758482_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000002113 222.0
CSH2_k127_6759398_0 regulation of translation K03530 - - 0.000000000000000000000000000000000000000000000000000000000000000001459 237.0
CSH2_k127_6759398_1 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000009199 229.0
CSH2_k127_6759398_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.00000000000000000000001755 101.0
CSH2_k127_6760413_0 PFAM Uncharacterised protein family (UPF0182) K09118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 559.0
CSH2_k127_6760413_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 453.0
CSH2_k127_6760413_10 Tetratricopeptide repeat - - - 0.000004031 60.0
CSH2_k127_6760413_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 350.0
CSH2_k127_6760413_3 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002539 256.0
CSH2_k127_6760413_4 PFAM Uncharacterised protein family UPF0182 K09118 - - 0.00000000000000000000000000000000000000000000000000000000000002417 220.0
CSH2_k127_6760413_5 Sigma factor PP2C-like phosphatases K04757,K07315 - 2.7.11.1,3.1.3.3 0.0000000000000000000000000000000000000000000001587 187.0
CSH2_k127_6760413_6 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000004519 172.0
CSH2_k127_6760413_7 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000003196 106.0
CSH2_k127_6760413_8 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000001945 82.0
CSH2_k127_6760413_9 DNA helicase K03656,K03657 - 3.6.4.12 0.00000000000002995 76.0
CSH2_k127_6761270_0 abc transporter (atp-binding protein) K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 400.0
CSH2_k127_6764458_0 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 473.0
CSH2_k127_6764458_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000004156 176.0
CSH2_k127_695656_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 301.0
CSH2_k127_695656_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 299.0
CSH2_k127_702204_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 370.0
CSH2_k127_702204_1 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004776 250.0
CSH2_k127_707914_0 PFAM CoA-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007946 352.0
CSH2_k127_707914_1 synthase K01654,K18430 - 2.5.1.101,2.5.1.56 0.0000000000000000000000000000000000000000000000000000000001155 211.0
CSH2_k127_759323_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000003201 247.0
CSH2_k127_765181_0 Mediates zinc uptake. May also transport other divalent cations K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 384.0
CSH2_k127_765181_1 COG NOG16854 non supervised orthologous group - - - 0.000000000000000002221 88.0
CSH2_k127_765181_2 Protein of unknown function (DUF454) K09790 - - 0.000000000004607 66.0
CSH2_k127_784819_0 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000009232 188.0
CSH2_k127_784819_1 Secondary thiamine-phosphate synthase enzyme - - - 0.000000000003005 66.0
CSH2_k127_784819_2 Peptidase_C39 like family - - - 0.000000002003 66.0
CSH2_k127_803187_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 453.0
CSH2_k127_803187_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 294.0
CSH2_k127_803187_2 PFAM ATP-binding region ATPase domain protein - - - 0.0000003738 56.0
CSH2_k127_804389_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000005796 168.0
CSH2_k127_804389_1 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000003165 57.0
CSH2_k127_824516_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 7.856e-199 637.0
CSH2_k127_824516_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 553.0
CSH2_k127_824516_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000002436 90.0
CSH2_k127_824516_2 Methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000147 236.0
CSH2_k127_824516_3 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K13613 - - 0.00000000000000000000000000000000000000000000000000001258 194.0
CSH2_k127_824516_4 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000003886 190.0
CSH2_k127_824516_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000004141 179.0
CSH2_k127_824516_6 Belongs to the phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000267 165.0
CSH2_k127_824516_7 Adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000006985 139.0
CSH2_k127_824516_8 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.000000000000000000000000000000000158 138.0
CSH2_k127_824516_9 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000002799 129.0
CSH2_k127_824917_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000001748 144.0
CSH2_k127_824917_1 Putative transposon-encoded protein (DUF2080) - - - 0.0000000000000000003866 87.0
CSH2_k127_824917_2 helix_turn_helix, Lux Regulon - - - 0.000000000000001192 84.0
CSH2_k127_83182_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000271 272.0
CSH2_k127_83182_1 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000009083 101.0
CSH2_k127_83182_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000003861 64.0
CSH2_k127_83182_3 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000002906 61.0
CSH2_k127_83182_4 Predicted membrane protein (DUF2232) - - - 0.00007066 54.0
CSH2_k127_832421_0 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 525.0
CSH2_k127_832421_1 Flagellar M-ring protein K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 343.0
CSH2_k127_832421_2 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000004077 78.0
CSH2_k127_832421_3 PFAM flagellar hook-basal body complex protein FliE K02408 - - 0.0000000001566 66.0
CSH2_k127_844722_0 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000007856 113.0
CSH2_k127_844722_1 PFAM General secretion pathway protein K K02460 - - 0.000000004475 63.0
CSH2_k127_851003_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 504.0
CSH2_k127_851003_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 285.0
CSH2_k127_851003_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000007076 168.0
CSH2_k127_851003_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000003141 124.0
CSH2_k127_851003_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000759 122.0
CSH2_k127_853253_0 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000002969 136.0
CSH2_k127_858863_0 PFAM Acetyl-CoA dehydrogenase-like C-terminal domain, Acyl-CoA dehydrogenase domain-containing protein, acyl-CoA dehydrogenase domain-containing protein K09456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 572.0
CSH2_k127_858863_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000001511 208.0
CSH2_k127_858863_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000002221 94.0
CSH2_k127_858863_3 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000001099 89.0
CSH2_k127_858863_5 TolA binding protein trimerisation - GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - 0.00002338 53.0
CSH2_k127_866337_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 4.202e-228 711.0
CSH2_k127_866337_1 PFAM Methyltransferase type 11 K03892 - - 0.000001657 51.0
CSH2_k127_9014_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000004936 138.0
CSH2_k127_910054_0 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 554.0
CSH2_k127_910054_1 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 298.0
CSH2_k127_910054_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001893 267.0
CSH2_k127_911845_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 533.0
CSH2_k127_911845_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000002306 63.0
CSH2_k127_911845_2 STAS domain - - - 0.00007765 49.0