Overview

ID MAG00607
Name CSH2_bin.19
Sample SMP0014
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order UBA10834
Family UBA10834
Genus COMBO-56-21
Species
Assembly information
Completeness (%) 86.17
Contamination (%) 1.22
GC content (%) 57.0
N50 (bp) 24,481
Genome size (bp) 1,691,469

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1486

Gene name Description KEGG GOs EC E-value Score Sequence
CSH2_k127_1085056_0 Multicopper oxidase K06324 - 1.16.3.3 1.305e-199 643.0
CSH2_k127_1085056_1 aldo keto reductase family K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 503.0
CSH2_k127_1085056_10 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000001753 217.0
CSH2_k127_1085056_11 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000001265 205.0
CSH2_k127_1085056_12 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000001206 198.0
CSH2_k127_1085056_13 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000006438 206.0
CSH2_k127_1085056_14 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000001161 197.0
CSH2_k127_1085056_15 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000003892 150.0
CSH2_k127_1085056_16 FMN binding K03809 - 1.6.5.2 0.00000000000000000000000000000000000009215 148.0
CSH2_k127_1085056_17 Putative TM nitroreductase - - - 0.000000000000000000000000000000001341 136.0
CSH2_k127_1085056_18 signal transduction histidine kinase - - - 0.00000000000000000000000000002499 133.0
CSH2_k127_1085056_19 Major Facilitator Superfamily - - - 0.000000000000000000002418 107.0
CSH2_k127_1085056_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 502.0
CSH2_k127_1085056_20 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000952 99.0
CSH2_k127_1085056_21 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000006526 97.0
CSH2_k127_1085056_22 Domain of unknown function (DUF4382) - - - 0.00000000002393 72.0
CSH2_k127_1085056_23 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000001513 70.0
CSH2_k127_1085056_24 SPFH domain-Band 7 family - - - 0.00001942 54.0
CSH2_k127_1085056_3 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 337.0
CSH2_k127_1085056_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009441 269.0
CSH2_k127_1085056_5 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000154 256.0
CSH2_k127_1085056_6 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.0000000000000000000000000000000000000000000000000000000000000000000003134 255.0
CSH2_k127_1085056_7 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000625 243.0
CSH2_k127_1085056_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000001798 232.0
CSH2_k127_1085056_9 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000006197 236.0
CSH2_k127_1123195_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 556.0
CSH2_k127_1123195_1 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 443.0
CSH2_k127_1123195_2 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000001008 127.0
CSH2_k127_1131000_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 328.0
CSH2_k127_1131000_1 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003092 263.0
CSH2_k127_1131000_2 SIS domain K08094 - 5.3.1.27 0.00000000000000000000000000000000000000000004858 166.0
CSH2_k127_1131000_3 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001356 164.0
CSH2_k127_1131000_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000001373 136.0
CSH2_k127_1131000_5 ThiF family - - - 0.0000000000000000000000000000000003642 141.0
CSH2_k127_1131000_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002076 130.0
CSH2_k127_1131000_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000003866 102.0
CSH2_k127_1131000_8 JAB/MPN domain K09613 GO:0000003,GO:0000338,GO:0000749,GO:0000754,GO:0000909,GO:0003006,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008180,GO:0008233,GO:0008234,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0010893,GO:0016787,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019538,GO:0019783,GO:0019784,GO:0019953,GO:0022414,GO:0023051,GO:0023058,GO:0030447,GO:0030448,GO:0030582,GO:0030584,GO:0031136,GO:0031137,GO:0031139,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032443,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0036211,GO:0040007,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045116,GO:0045834,GO:0045940,GO:0046889,GO:0046890,GO:0046999,GO:0048518,GO:0048522,GO:0048583,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050810,GO:0050896,GO:0051704,GO:0051716,GO:0061458,GO:0062012,GO:0062013,GO:0065007,GO:0070011,GO:0070452,GO:0070646,GO:0070647,GO:0070791,GO:0070887,GO:0071310,GO:0071444,GO:0071704,GO:0075259,GO:0080090,GO:0106118,GO:0106120,GO:0140096,GO:1901564,GO:1902930,GO:1902932,GO:2000241,GO:2000243 - 0.0000000000004664 78.0
CSH2_k127_1131000_9 Ubiquitin-conjugating enzyme E2, catalytic domain homologues K13960 GO:0000209,GO:0003674,GO:0003682,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006513,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0031625,GO:0031974,GO:0031981,GO:0032446,GO:0033554,GO:0034641,GO:0035519,GO:0036211,GO:0036297,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044314,GO:0044389,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0051865,GO:0061630,GO:0061631,GO:0061650,GO:0061659,GO:0070013,GO:0070534,GO:0070647,GO:0070936,GO:0070979,GO:0071704,GO:0085020,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.2.23 0.000000000002267 78.0
CSH2_k127_1250297_0 - - - - 0.00000000000000000000000000000000000000000000007624 186.0
CSH2_k127_1250297_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000003857 62.0
CSH2_k127_1250297_2 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0005938 46.0
CSH2_k127_1441100_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 377.0
CSH2_k127_1441100_1 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 293.0
CSH2_k127_1441100_2 - - - - 0.0000000000000000000000000000000000002518 151.0
CSH2_k127_1484429_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.1e-198 634.0
CSH2_k127_1484429_1 Nickel-dependent hydrogenase K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 334.0
CSH2_k127_1484429_2 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 302.0
CSH2_k127_1484429_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002504 277.0
CSH2_k127_1484429_4 hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000345 202.0
CSH2_k127_1484429_5 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.000000000000000000000000000000000000002685 170.0
CSH2_k127_1484429_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000002877 124.0
CSH2_k127_1484429_7 collagen metabolic process K17948 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0016853,GO:0016854,GO:0016857,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 5.1.3.24 0.00000000000000003277 96.0
CSH2_k127_1484429_8 photoreceptor activity - - - 0.0000000007847 73.0
CSH2_k127_1484429_9 Hydrogenase maturation protease K08315 - 3.4.23.51 0.000000007189 66.0
CSH2_k127_149630_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 443.0
CSH2_k127_149630_1 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000002224 158.0
CSH2_k127_149630_2 - - - - 0.00000000000000000000004543 100.0
CSH2_k127_149630_3 Acetyltransferase (GNAT) family - - - 0.0000000000000000000552 100.0
CSH2_k127_149630_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 - 2.1.1.63 0.000000000000003585 81.0
CSH2_k127_149630_5 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000001772 54.0
CSH2_k127_1514884_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 3.78e-316 982.0
CSH2_k127_1514884_1 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 305.0
CSH2_k127_1514884_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000002973 100.0
CSH2_k127_1514884_11 PFAM 4-vinyl reductase, 4VR K07013 - - 0.000000000000000000003545 99.0
CSH2_k127_1514884_2 Helix-turn-helix XRE-family like proteins K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 295.0
CSH2_k127_1514884_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000002082 181.0
CSH2_k127_1514884_4 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000006992 163.0
CSH2_k127_1514884_5 GvpD gas vesicle protein - - - 0.000000000000000000000000000000000000004753 155.0
CSH2_k127_1514884_6 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.00000000000000000000000000000000001285 150.0
CSH2_k127_1514884_7 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.00000000000000000000000011 113.0
CSH2_k127_1514884_8 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000000000000008071 110.0
CSH2_k127_1514884_9 - - - - 0.00000000000000000000001374 107.0
CSH2_k127_1559938_0 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 296.0
CSH2_k127_1559938_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001159 259.0
CSH2_k127_1559938_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000007217 164.0
CSH2_k127_1559938_3 - - - - 0.000000000000000000000000000000000003007 148.0
CSH2_k127_1559938_4 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000004698 97.0
CSH2_k127_1695995_0 Alanine-glyoxylate amino-transferase K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 449.0
CSH2_k127_1695995_1 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 359.0
CSH2_k127_1695995_2 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001239 251.0
CSH2_k127_1695995_3 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003651 244.0
CSH2_k127_1695995_4 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000002167 164.0
CSH2_k127_1695995_5 Nicotinamide-nucleotide adenylyltransferase K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.000000000000000015 85.0
CSH2_k127_1724305_0 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000009722 219.0
CSH2_k127_1724305_1 - - - - 0.00000000000009512 78.0
CSH2_k127_1724564_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1032.0
CSH2_k127_1724564_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.855e-277 872.0
CSH2_k127_1724564_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 347.0
CSH2_k127_1724564_11 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 351.0
CSH2_k127_1724564_12 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 330.0
CSH2_k127_1724564_13 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000016 284.0
CSH2_k127_1724564_14 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002699 287.0
CSH2_k127_1724564_15 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000000000000000000000000000000001062 268.0
CSH2_k127_1724564_16 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003024 270.0
CSH2_k127_1724564_17 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000636 272.0
CSH2_k127_1724564_18 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000006513 222.0
CSH2_k127_1724564_19 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000000000000000000000002045 214.0
CSH2_k127_1724564_2 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.111e-214 681.0
CSH2_k127_1724564_20 nitrogen compound transport K02033,K12369 - - 0.00000000000000000000000000000000000000000000000000000000008276 216.0
CSH2_k127_1724564_21 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000002041 209.0
CSH2_k127_1724564_22 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000002498 201.0
CSH2_k127_1724564_23 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000005733 196.0
CSH2_k127_1724564_24 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000000002634 170.0
CSH2_k127_1724564_25 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000001387 189.0
CSH2_k127_1724564_26 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000002316 172.0
CSH2_k127_1724564_27 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000005233 163.0
CSH2_k127_1724564_28 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000000000000001107 160.0
CSH2_k127_1724564_29 - - - - 0.00000000000000000000000000000000000000001383 158.0
CSH2_k127_1724564_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.234e-197 627.0
CSH2_k127_1724564_30 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000003166 153.0
CSH2_k127_1724564_31 Protein of unknown function (DUF357) K09728 - - 0.000000000000000000000000000000000001771 143.0
CSH2_k127_1724564_32 Transferase hexapeptide repeat - - - 0.000000000000000000000000000000000229 138.0
CSH2_k127_1724564_33 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.000000000000000000000000000001126 121.0
CSH2_k127_1724564_34 4Fe-4S ferredoxin, iron-sulfur binding K00196 - - 0.00000000000000000000000000001543 125.0
CSH2_k127_1724564_35 Thiamine-binding protein - - - 0.0000000000000000000000000003797 117.0
CSH2_k127_1724564_36 Major Facilitator Superfamily - - - 0.0000000000000000000000001726 120.0
CSH2_k127_1724564_37 Fcf1 K07158 - - 0.000000000000000000000001635 106.0
CSH2_k127_1724564_38 Rhodanese Homology Domain - - - 0.000000000000000000003413 98.0
CSH2_k127_1724564_39 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000001072 94.0
CSH2_k127_1724564_4 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 570.0
CSH2_k127_1724564_40 4Fe-4S dicluster domain - - - 0.00000000000000000008638 95.0
CSH2_k127_1724564_41 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000009155 94.0
CSH2_k127_1724564_42 EamA-like transporter family - - - 0.00000000000005969 82.0
CSH2_k127_1724564_43 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000004456 70.0
CSH2_k127_1724564_44 - - - - 0.0002006 48.0
CSH2_k127_1724564_5 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 551.0
CSH2_k127_1724564_6 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 556.0
CSH2_k127_1724564_7 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 533.0
CSH2_k127_1724564_8 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 489.0
CSH2_k127_1724564_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 393.0
CSH2_k127_1740719_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.995e-215 680.0
CSH2_k127_1740719_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 439.0
CSH2_k127_1740719_10 Phosphohydrolase K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001631 255.0
CSH2_k127_1740719_11 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000006168 243.0
CSH2_k127_1740719_12 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000003237 221.0
CSH2_k127_1740719_13 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000001554 229.0
CSH2_k127_1740719_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004977 210.0
CSH2_k127_1740719_15 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002564 199.0
CSH2_k127_1740719_16 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000005179 205.0
CSH2_k127_1740719_17 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.0000000000000000000000000000000000000000000000000000005041 200.0
CSH2_k127_1740719_18 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000000000003365 197.0
CSH2_k127_1740719_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000007468 191.0
CSH2_k127_1740719_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 407.0
CSH2_k127_1740719_20 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000001899 204.0
CSH2_k127_1740719_21 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000009973 186.0
CSH2_k127_1740719_22 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000175 203.0
CSH2_k127_1740719_23 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000006929 184.0
CSH2_k127_1740719_24 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000006934 173.0
CSH2_k127_1740719_25 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000006409 161.0
CSH2_k127_1740719_26 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000001631 159.0
CSH2_k127_1740719_27 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000004888 151.0
CSH2_k127_1740719_28 structural constituent of ribosome K02907 - - 0.00000000000000000000000000000000000002591 153.0
CSH2_k127_1740719_29 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002706 143.0
CSH2_k127_1740719_3 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 401.0
CSH2_k127_1740719_30 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000004209 141.0
CSH2_k127_1740719_31 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000006157 138.0
CSH2_k127_1740719_32 Integral membrane protein DUF106 - - - 0.00000000000000000000000000000003806 134.0
CSH2_k127_1740719_33 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001301 121.0
CSH2_k127_1740719_34 protein conserved in archaea - - - 0.00000000000000000000000000005547 123.0
CSH2_k127_1740719_35 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000009925 116.0
CSH2_k127_1740719_36 Tripartite tricarboxylate transporter TctA family K08971 - - 0.000000000000000000008561 106.0
CSH2_k127_1740719_37 ribosomal protein S14 K02954 - - 0.0000000000000000002196 91.0
CSH2_k127_1740719_38 Belongs to the UPF0248 family K09715 - - 0.0000000000000000002253 91.0
CSH2_k127_1740719_39 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.00000000000000003243 87.0
CSH2_k127_1740719_4 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 322.0
CSH2_k127_1740719_40 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000008192 88.0
CSH2_k127_1740719_41 Ribosomal L29 protein K02904 - - 0.00000000000001539 78.0
CSH2_k127_1740719_42 - - - - 0.0000000000000307 76.0
CSH2_k127_1740719_43 - - - - 0.00000000006575 68.0
CSH2_k127_1740719_5 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 311.0
CSH2_k127_1740719_6 ribosomal protein S3 K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 299.0
CSH2_k127_1740719_7 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000163 282.0
CSH2_k127_1740719_8 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005144 278.0
CSH2_k127_1740719_9 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001311 254.0
CSH2_k127_1782124_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 532.0
CSH2_k127_1782124_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 332.0
CSH2_k127_1782124_10 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000004165 162.0
CSH2_k127_1782124_11 Response regulator receiver domain K03413 - - 0.000000000000000000000003504 108.0
CSH2_k127_1782124_12 Matrixin K06974 - - 0.000000000000000000000004073 108.0
CSH2_k127_1782124_13 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000123 87.0
CSH2_k127_1782124_14 Acetyltransferase, gnat family - - - 0.00000000000004172 82.0
CSH2_k127_1782124_15 but it may be involved in stabilization of the trimeric complex - - - 0.000000002194 60.0
CSH2_k127_1782124_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 323.0
CSH2_k127_1782124_3 HisG, C-terminal domain K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003095 283.0
CSH2_k127_1782124_4 DNA polymerase alpha chain like domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000005436 226.0
CSH2_k127_1782124_5 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000009126 226.0
CSH2_k127_1782124_6 Histidine biosynthesis protein K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000002561 216.0
CSH2_k127_1782124_7 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000003094 213.0
CSH2_k127_1782124_8 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000001758 205.0
CSH2_k127_1782124_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000008536 204.0
CSH2_k127_1847971_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 515.0
CSH2_k127_1847971_1 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000000007974 190.0
CSH2_k127_1847971_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000216 117.0
CSH2_k127_1857370_0 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000002776 256.0
CSH2_k127_1857370_1 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000004328 85.0
CSH2_k127_1857370_2 - - - - 0.00000000006105 74.0
CSH2_k127_1857370_3 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000001183 53.0
CSH2_k127_1857370_4 Thioredoxin domain - - - 0.0002743 47.0
CSH2_k127_1867025_0 Required for chromosome condensation and partitioning K03529 - - 3.24e-256 832.0
CSH2_k127_1867025_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 429.0
CSH2_k127_1867025_10 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000000000000000001244 203.0
CSH2_k127_1867025_11 and related - - - 0.00000000000000000000000000000000000000000000000000000596 201.0
CSH2_k127_1867025_12 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000001825 176.0
CSH2_k127_1867025_13 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000009375 180.0
CSH2_k127_1867025_14 TIGRFAM segregation and condensation protein B K06024 - - 0.000000000000000000000000000001773 126.0
CSH2_k127_1867025_15 snRNP Sm proteins K04796 - - 0.0000000000000000000347 91.0
CSH2_k127_1867025_16 Clostripain family - - - 0.0006732 51.0
CSH2_k127_1867025_2 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 372.0
CSH2_k127_1867025_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 355.0
CSH2_k127_1867025_4 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 332.0
CSH2_k127_1867025_5 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 307.0
CSH2_k127_1867025_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001619 275.0
CSH2_k127_1867025_7 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009677 274.0
CSH2_k127_1867025_8 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000005027 226.0
CSH2_k127_1867025_9 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000007858 202.0
CSH2_k127_1872439_0 PFAM sodium calcium exchanger K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001677 283.0
CSH2_k127_1872439_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000003485 200.0
CSH2_k127_1872439_2 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.0000000000000000000000000000000000000000005497 177.0
CSH2_k127_1872439_3 Major Facilitator K08151,K08153 - - 0.0000000000000003495 92.0
CSH2_k127_1872439_4 Acetyltransferase (GNAT) domain - - - 0.000179 51.0
CSH2_k127_1876544_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 1.393e-212 670.0
CSH2_k127_1876544_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 392.0
CSH2_k127_1876544_2 - - - - 0.00000000000000000000000000000000000003826 154.0
CSH2_k127_1876544_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000008618 146.0
CSH2_k127_1876544_4 COG1522 Transcriptional regulators - - - 0.000000000000000000007002 100.0
CSH2_k127_1876544_5 YHS domain - - - 0.000000000000000008997 87.0
CSH2_k127_1895581_0 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000055 271.0
CSH2_k127_1895581_1 TatD related DNase K07049 - - 0.000000000000000000000000000000000000000002414 160.0
CSH2_k127_1895581_2 PFAM Peptidase C11, clostripain - - - 0.00000000000000000000000007926 119.0
CSH2_k127_19540_0 acetyl-CoA hydrolase transferase - - - 1.48e-219 698.0
CSH2_k127_19540_1 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 427.0
CSH2_k127_19540_10 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000336 164.0
CSH2_k127_19540_11 Citrate transporter K14445 - - 0.0000000000000000000001575 101.0
CSH2_k127_19540_12 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000004148 57.0
CSH2_k127_19540_13 Belongs to the peptidase S8 family K01361,K08652,K14647 GO:0005575,GO:0005576 3.4.21.110,3.4.21.96 0.00000004007 68.0
CSH2_k127_19540_14 Belongs to the peptidase S8 family K01361,K08652,K14647 GO:0005575,GO:0005576 3.4.21.110,3.4.21.96 0.000006057 61.0
CSH2_k127_19540_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 360.0
CSH2_k127_19540_3 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 391.0
CSH2_k127_19540_4 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 386.0
CSH2_k127_19540_5 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 305.0
CSH2_k127_19540_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 298.0
CSH2_k127_19540_7 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000005886 251.0
CSH2_k127_19540_8 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000001726 246.0
CSH2_k127_19540_9 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000001385 236.0
CSH2_k127_1959_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 7e-323 1036.0
CSH2_k127_1959_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 1.202e-239 761.0
CSH2_k127_1959_10 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 380.0
CSH2_k127_1959_11 ABC transporter K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 376.0
CSH2_k127_1959_12 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 371.0
CSH2_k127_1959_13 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 372.0
CSH2_k127_1959_14 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 368.0
CSH2_k127_1959_15 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 363.0
CSH2_k127_1959_16 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 352.0
CSH2_k127_1959_17 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 306.0
CSH2_k127_1959_18 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 308.0
CSH2_k127_1959_19 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000265 296.0
CSH2_k127_1959_2 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 563.0
CSH2_k127_1959_20 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000005135 255.0
CSH2_k127_1959_21 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000787 249.0
CSH2_k127_1959_22 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000007786 249.0
CSH2_k127_1959_23 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001188 237.0
CSH2_k127_1959_24 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000007313 229.0
CSH2_k127_1959_25 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.0000000000000000000000000000000000000000000000000000000000000001706 228.0
CSH2_k127_1959_26 PFAM Major Facilitator Superfamily K19576 - - 0.00000000000000000000000000000000000000000000000000000001542 212.0
CSH2_k127_1959_27 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000004794 198.0
CSH2_k127_1959_28 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000000004747 195.0
CSH2_k127_1959_29 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000000000000000000276 201.0
CSH2_k127_1959_3 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 559.0
CSH2_k127_1959_30 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000000000000000000000000000000000000000000000001871 199.0
CSH2_k127_1959_31 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000001011 193.0
CSH2_k127_1959_32 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000000000000001293 185.0
CSH2_k127_1959_33 KaiC - - - 0.000000000000000000000000000000000006684 149.0
CSH2_k127_1959_34 MFS_1 like family K08153 - - 0.0000000000000000000000000000001691 140.0
CSH2_k127_1959_35 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000000132 128.0
CSH2_k127_1959_36 DnaB-like helicase C terminal domain K08482 - - 0.0000000000000000000000000000388 127.0
CSH2_k127_1959_37 helix_turn_helix ASNC type K06154 - - 0.00000000000000000000000004121 113.0
CSH2_k127_1959_38 SnoaL-like domain - - - 0.0000000000000000000006507 101.0
CSH2_k127_1959_39 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000000007383 90.0
CSH2_k127_1959_4 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 518.0
CSH2_k127_1959_40 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000000000002505 86.0
CSH2_k127_1959_41 EamA-like transporter family - - - 0.00000000000003482 83.0
CSH2_k127_1959_42 transcriptional regulators - - - 0.000000000001378 73.0
CSH2_k127_1959_43 - - - - 0.000000000003697 68.0
CSH2_k127_1959_44 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.000000000006914 69.0
CSH2_k127_1959_45 Helix-turn-helix domain - - - 0.000000000007848 70.0
CSH2_k127_1959_46 Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family K10352,K18669 GO:0000003,GO:0000146,GO:0000166,GO:0000278,GO:0000281,GO:0000902,GO:0000904,GO:0000910,GO:0001568,GO:0001654,GO:0001655,GO:0001667,GO:0001700,GO:0001701,GO:0001725,GO:0001736,GO:0001738,GO:0001745,GO:0001764,GO:0001778,GO:0001894,GO:0001944,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0002791,GO:0002793,GO:0003002,GO:0003006,GO:0003008,GO:0003012,GO:0003205,GO:0003279,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003774,GO:0003779,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005826,GO:0005829,GO:0005844,GO:0005856,GO:0005886,GO:0005903,GO:0005911,GO:0005938,GO:0006810,GO:0006887,GO:0006928,GO:0006929,GO:0006930,GO:0006935,GO:0006936,GO:0006950,GO:0006996,GO:0007009,GO:0007010,GO:0007015,GO:0007049,GO:0007097,GO:0007155,GO:0007163,GO:0007164,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007386,GO:0007389,GO:0007391,GO:0007392,GO:0007395,GO:0007399,GO:0007405,GO:0007409,GO:0007411,GO:0007417,GO:0007420,GO:0007423,GO:0007424,GO:0007431,GO:0007435,GO:0007442,GO:0007443,GO:0007444,GO:0007455,GO:0007472,GO:0007476,GO:0007494,GO:0007496,GO:0007507,GO:0007512,GO:0007552,GO:0007560,GO:0008092,GO:0008104,GO:0008144,GO:0008150,GO:0008258,GO:0008283,GO:0008356,GO:0008360,GO:0008544,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009798,GO:0009886,GO:0009887,GO:0009888,GO:0009913,GO:0009952,GO:0009987,GO:0010256,GO:0010631,GO:0010830,GO:0010927,GO:0014706,GO:0015629,GO:0016020,GO:0016043,GO:0016192,GO:0016318,GO:0016331,GO:0016459,GO:0016460,GO:0016461,GO:0016462,GO:0016477,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017022,GO:0017076,GO:0017111,GO:0017145,GO:0019953,GO:0021537,GO:0021549,GO:0021591,GO:0021592,GO:0021670,GO:0021678,GO:0021680,GO:0021695,GO:0022008,GO:0022037,GO:0022402,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022610,GO:0022612,GO:0030010,GO:0030016,GO:0030017,GO:0030018,GO:0030027,GO:0030029,GO:0030030,GO:0030031,GO:0030036,GO:0030048,GO:0030054,GO:0030154,GO:0030182,GO:0030239,GO:0030424,GO:0030425,GO:0030426,GO:0030427,GO:0030496,GO:0030554,GO:0030707,GO:0030855,GO:0030863,GO:0030864,GO:0030898,GO:0030900,GO:0030902,GO:0031032,GO:0031033,GO:0031034,GO:0031036,GO:0031038,GO:0031175,GO:0031252,GO:0031674,GO:0032027,GO:0032153,GO:0032154,GO:0032155,GO:0032432,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032940,GO:0032982,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033267,GO:0034613,GO:0034622,GO:0035017,GO:0035026,GO:0035051,GO:0035107,GO:0035114,GO:0035120,GO:0035150,GO:0035151,GO:0035152,GO:0035159,GO:0035214,GO:0035220,GO:0035239,GO:0035272,GO:0035277,GO:0035295,GO:0035315,GO:0035316,GO:0035317,GO:0035613,GO:0035639,GO:0035904,GO:0036094,GO:0036445,GO:0036477,GO:0040011,GO:0042060,GO:0042067,GO:0042221,GO:0042330,GO:0042335,GO:0042592,GO:0042623,GO:0042641,GO:0042692,GO:0042802,GO:0042995,GO:0043005,GO:0043009,GO:0043010,GO:0043025,GO:0043167,GO:0043168,GO:0043197,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043531,GO:0043933,GO:0044085,GO:0044291,GO:0044297,GO:0044309,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044877,GO:0045165,GO:0045177,GO:0045179,GO:0045185,GO:0045196,GO:0045200,GO:0045202,GO:0045214,GO:0045595,GO:0046663,GO:0046664,GO:0046903,GO:0046907,GO:0048027,GO:0048103,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048546,GO:0048563,GO:0048565,GO:0048569,GO:0048592,GO:0048598,GO:0048609,GO:0048619,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048738,GO:0048749,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0048871,GO:0050708,GO:0050714,GO:0050789,GO:0050793,GO:0050794,GO:0050808,GO:0050877,GO:0050885,GO:0050896,GO:0050905,GO:0051015,GO:0051017,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051128,GO:0051146,GO:0051147,GO:0051153,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051235,GO:0051259,GO:0051301,GO:0051640,GO:0051641,GO:0051647,GO:0051649,GO:0051651,GO:0051656,GO:0051674,GO:0051704,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055012,GO:0055013,GO:0055015,GO:0055057,GO:0055059,GO:0055123,GO:0060041,GO:0060142,GO:0060249,GO:0060289,GO:0060322,GO:0060429,GO:0060537,GO:0060541,GO:0060562,GO:0060571,GO:0060840,GO:0060972,GO:0060976,GO:0061024,GO:0061061,GO:0061326,GO:0061333,GO:0061351,GO:0061525,GO:0061564,GO:0061572,GO:0061640,GO:0065003,GO:0065007,GO:0065008,GO:0070201,GO:0070650,GO:0070727,GO:0070925,GO:0070938,GO:0070986,GO:0071214,GO:0071260,GO:0071496,GO:0071840,GO:0071944,GO:0072001,GO:0072002,GO:0072089,GO:0072358,GO:0072359,GO:0090066,GO:0090087,GO:0090130,GO:0090132,GO:0090596,GO:0097159,GO:0097367,GO:0097435,GO:0097447,GO:0097458,GO:0097485,GO:0097513,GO:0097517,GO:0098590,GO:0098722,GO:0098794,GO:0098862,GO:0098885,GO:0099010,GO:0099080,GO:0099081,GO:0099512,GO:0099563,GO:0099568,GO:0099738,GO:0104004,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:1901265,GO:1901363,GO:1901739,GO:1903047,GO:1903530,GO:1903532,GO:1904951,GO:1990904 2.7.12.1 0.00000004494 68.0
CSH2_k127_1959_47 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.000004904 51.0
CSH2_k127_1959_48 - - - - 0.00001303 50.0
CSH2_k127_1959_49 EamA-like transporter family - - - 0.0004807 51.0
CSH2_k127_1959_5 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 518.0
CSH2_k127_1959_51 PFAM regulatory protein AsnC Lrp family - - - 0.0008684 44.0
CSH2_k127_1959_6 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 522.0
CSH2_k127_1959_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 515.0
CSH2_k127_1959_8 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 518.0
CSH2_k127_1959_9 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 439.0
CSH2_k127_2019779_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 307.0
CSH2_k127_2019779_1 Clostripain family - - - 0.000000000000000000000000000000000000000000000000000000000000000000006105 269.0
CSH2_k127_2019779_10 amine dehydrogenase activity - - - 0.000000003801 70.0
CSH2_k127_2019779_11 - - - - 0.00000002927 60.0
CSH2_k127_2019779_2 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000000000000002065 185.0
CSH2_k127_2019779_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000001378 196.0
CSH2_k127_2019779_4 - - - - 0.000000000000000000000000000000000000000000000554 177.0
CSH2_k127_2019779_5 PFAM PKD domain containing protein - - - 0.000000000000000000000000003958 131.0
CSH2_k127_2019779_6 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000003244 119.0
CSH2_k127_2019779_7 Tetratricopeptide repeat - - - 0.00000000000000000004592 106.0
CSH2_k127_2019779_8 - - - - 0.0000000000000008723 91.0
CSH2_k127_2138208_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 547.0
CSH2_k127_2138208_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 487.0
CSH2_k127_224416_0 Peptidase S8 and S53 subtilisin kexin sedolisin K01342,K14645 - 3.4.21.62 0.000000000000000000000000000000000000000000000000000000000000006349 242.0
CSH2_k127_224416_1 transcription regulator activity - - - 0.0000000000000000000000000000000002103 138.0
CSH2_k127_224416_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000004982 93.0
CSH2_k127_224416_3 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000001582 78.0
CSH2_k127_224416_4 Transmembrane secretion effector - - - 0.00000003304 66.0
CSH2_k127_2361533_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 507.0
CSH2_k127_2361533_1 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000001203 198.0
CSH2_k127_2361533_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000002637 130.0
CSH2_k127_2368066_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 532.0
CSH2_k127_2368066_1 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 513.0
CSH2_k127_2368066_10 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000444 136.0
CSH2_k127_2368066_11 - - - - 0.0000000000000000000000000000006589 130.0
CSH2_k127_2368066_12 OsmC-like protein - - - 0.00000000000000000000000000002563 123.0
CSH2_k127_2368066_13 Major Facilitator - - - 0.00000000000000000000000000005426 131.0
CSH2_k127_2368066_14 - - - - 0.00000000000000001164 89.0
CSH2_k127_2368066_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 446.0
CSH2_k127_2368066_3 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 422.0
CSH2_k127_2368066_4 glutamate synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 386.0
CSH2_k127_2368066_5 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 368.0
CSH2_k127_2368066_6 Citrate transporter K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008875 276.0
CSH2_k127_2368066_7 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004136 237.0
CSH2_k127_2368066_8 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000002342 213.0
CSH2_k127_2368066_9 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000001464 194.0
CSH2_k127_2374354_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 560.0
CSH2_k127_2374354_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 406.0
CSH2_k127_2374354_10 Lrp/AsnC ligand binding domain - - - 0.00000000000001139 77.0
CSH2_k127_2374354_11 Belongs to the UPF0235 family K09131 - - 0.000000000009369 70.0
CSH2_k127_2374354_12 protein conserved in archaea K09723 - - 0.00000001169 64.0
CSH2_k127_2374354_13 - K07725 - - 0.00004461 53.0
CSH2_k127_2374354_14 hydrolase of the HAD superfamily K07015 - - 0.00006573 53.0
CSH2_k127_2374354_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 316.0
CSH2_k127_2374354_3 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004313 263.0
CSH2_k127_2374354_4 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002812 265.0
CSH2_k127_2374354_5 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000002839 215.0
CSH2_k127_2374354_6 Metallo-beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000002426 185.0
CSH2_k127_2374354_7 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000003588 126.0
CSH2_k127_2374354_8 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.0000000000000000000000002493 108.0
CSH2_k127_2374354_9 metal ion binding - - - 0.0000000000000000008793 91.0
CSH2_k127_2556789_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1046.0
CSH2_k127_2556789_1 KH, type 1, domain K07041 - - 4.419e-267 835.0
CSH2_k127_2556789_10 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 481.0
CSH2_k127_2556789_11 Pfam:DUF650 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 471.0
CSH2_k127_2556789_12 DNA primase K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 433.0
CSH2_k127_2556789_13 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 420.0
CSH2_k127_2556789_14 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 405.0
CSH2_k127_2556789_15 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 398.0
CSH2_k127_2556789_16 CoA binding domain K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 398.0
CSH2_k127_2556789_17 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 382.0
CSH2_k127_2556789_18 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 409.0
CSH2_k127_2556789_19 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 377.0
CSH2_k127_2556789_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.031e-230 737.0
CSH2_k127_2556789_20 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 368.0
CSH2_k127_2556789_21 PFAM major facilitator superfamily MFS_1 K08217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 372.0
CSH2_k127_2556789_22 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 391.0
CSH2_k127_2556789_23 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 374.0
CSH2_k127_2556789_24 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 336.0
CSH2_k127_2556789_25 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 333.0
CSH2_k127_2556789_26 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 332.0
CSH2_k127_2556789_27 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 332.0
CSH2_k127_2556789_28 PP-loop family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 313.0
CSH2_k127_2556789_29 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 300.0
CSH2_k127_2556789_3 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 5.43e-224 706.0
CSH2_k127_2556789_30 PFAM AIR synthase related protein K07123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 295.0
CSH2_k127_2556789_31 Type II/IV secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 302.0
CSH2_k127_2556789_32 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000005094 269.0
CSH2_k127_2556789_33 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000004931 256.0
CSH2_k127_2556789_34 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000009393 254.0
CSH2_k127_2556789_35 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000003454 249.0
CSH2_k127_2556789_36 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000008223 244.0
CSH2_k127_2556789_37 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000008441 231.0
CSH2_k127_2556789_38 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000002146 233.0
CSH2_k127_2556789_39 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000003423 230.0
CSH2_k127_2556789_4 AAA domain K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 608.0
CSH2_k127_2556789_40 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000529 225.0
CSH2_k127_2556789_41 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000000000000003636 228.0
CSH2_k127_2556789_42 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000802 217.0
CSH2_k127_2556789_43 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000001432 208.0
CSH2_k127_2556789_44 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000001806 211.0
CSH2_k127_2556789_45 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.000000000000000000000000000000000000000000000000000004547 197.0
CSH2_k127_2556789_46 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000001331 184.0
CSH2_k127_2556789_47 Archaeal holliday junction resolvase (hjc) - - - 0.0000000000000000000000000000000000000000000000002803 182.0
CSH2_k127_2556789_48 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000004146 175.0
CSH2_k127_2556789_49 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000006232 179.0
CSH2_k127_2556789_5 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 574.0
CSH2_k127_2556789_50 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000004883 179.0
CSH2_k127_2556789_51 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000000000000000000000000000000000000004991 192.0
CSH2_k127_2556789_52 LysE type translocator - - - 0.0000000000000000000000000000000000000000000025 172.0
CSH2_k127_2556789_53 Oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000004623 169.0
CSH2_k127_2556789_54 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000000000000000000000000000006443 167.0
CSH2_k127_2556789_55 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000001194 160.0
CSH2_k127_2556789_56 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.0000000000000000000000000000000000000001103 154.0
CSH2_k127_2556789_57 - - - - 0.0000000000000000000000000000000000000004374 160.0
CSH2_k127_2556789_58 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000008873 156.0
CSH2_k127_2556789_59 - - - - 0.000000000000000000000000000000000209 139.0
CSH2_k127_2556789_6 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 505.0
CSH2_k127_2556789_60 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.0000000000000000000000000000000006399 139.0
CSH2_k127_2556789_61 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000000000002727 116.0
CSH2_k127_2556789_62 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.000000000000000000000000004089 119.0
CSH2_k127_2556789_63 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000002391 117.0
CSH2_k127_2556789_64 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00188 - 1.2.7.7 0.0000000000000000000000002378 108.0
CSH2_k127_2556789_65 - - - - 0.000000000000000000000002437 108.0
CSH2_k127_2556789_66 - - - - 0.000000000000000000000009303 117.0
CSH2_k127_2556789_67 Belongs to the PDCD5 family K06875 - - 0.0000000000000000000005639 98.0
CSH2_k127_2556789_68 EamA-like transporter family - - - 0.000000000000000000002026 105.0
CSH2_k127_2556789_69 cheY-homologous receiver domain - - - 0.00000000000000000001379 98.0
CSH2_k127_2556789_7 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 496.0
CSH2_k127_2556789_70 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0003674,GO:0003824,GO:0003882,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.8 0.00000000000000000006211 99.0
CSH2_k127_2556789_71 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000002238 87.0
CSH2_k127_2556789_72 Pfam:DUF59 - - - 0.000000000000000005415 87.0
CSH2_k127_2556789_73 cheY-homologous receiver domain K03413 - - 0.00000000000000001624 87.0
CSH2_k127_2556789_74 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000001643 81.0
CSH2_k127_2556789_75 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000000003467 78.0
CSH2_k127_2556789_76 exosome subunit K07581 - - 0.00000000000003989 79.0
CSH2_k127_2556789_77 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.000000000000149 72.0
CSH2_k127_2556789_78 COG1522 Transcriptional regulators - - - 0.0000000001503 72.0
CSH2_k127_2556789_79 cheY-homologous receiver domain - - - 0.000008758 59.0
CSH2_k127_2556789_8 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 492.0
CSH2_k127_2556789_80 transcriptional K03892 - - 0.0000303 56.0
CSH2_k127_2556789_81 - - - - 0.00009504 53.0
CSH2_k127_2556789_82 RnfH family Ubiquitin K09801 - - 0.0009325 46.0
CSH2_k127_2556789_9 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 481.0
CSH2_k127_2557117_0 CobW/HypB/UreG, nucleotide-binding domain - - - 5.126e-202 636.0
CSH2_k127_2557117_1 MGS-like domain K00602,K01492 - 2.1.2.2,2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 549.0
CSH2_k127_2557117_10 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000005305 53.0
CSH2_k127_2557117_2 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000000000000000000000001031 196.0
CSH2_k127_2557117_3 amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000004693 184.0
CSH2_k127_2557117_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890,K04566,K06878 - 6.1.1.10,6.1.1.20,6.1.1.6 0.00000000000000000000000000000000000000000001799 164.0
CSH2_k127_2557117_5 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000001215 179.0
CSH2_k127_2557117_6 Putative transposase DNA-binding domain - - - 0.0000000000000000000000000000000007418 144.0
CSH2_k127_2557117_7 - - - - 0.0000000000000000002709 92.0
CSH2_k127_2557117_8 transcriptional regulators - - - 0.000000000000000006558 88.0
CSH2_k127_2557117_9 KaiC - - - 0.0000009386 59.0
CSH2_k127_2568753_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.882e-272 853.0
CSH2_k127_2568753_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.686e-199 638.0
CSH2_k127_2568753_10 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000001013 162.0
CSH2_k127_2568753_11 SPFH domain-containing protein K07192 - - 0.0000000000000000000000000005139 129.0
CSH2_k127_2568753_12 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000354 117.0
CSH2_k127_2568753_13 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000003431 85.0
CSH2_k127_2568753_14 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000003448 83.0
CSH2_k127_2568753_15 EamA-like transporter family - - - 0.000007021 57.0
CSH2_k127_2568753_16 EamA-like transporter family - - - 0.0009086 50.0
CSH2_k127_2568753_2 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 611.0
CSH2_k127_2568753_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 433.0
CSH2_k127_2568753_4 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 409.0
CSH2_k127_2568753_5 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000003369 267.0
CSH2_k127_2568753_6 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002983 257.0
CSH2_k127_2568753_7 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000897 255.0
CSH2_k127_2568753_8 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000005342 192.0
CSH2_k127_2568753_9 InterPro IPR014922 - - - 0.000000000000000000000000000000000000000000000102 172.0
CSH2_k127_2575118_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 533.0
CSH2_k127_2575118_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 476.0
CSH2_k127_2575118_2 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000004732 238.0
CSH2_k127_2575118_3 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000004039 109.0
CSH2_k127_2575118_4 - - - - 0.0000000000003643 71.0
CSH2_k127_2577546_0 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 443.0
CSH2_k127_2577546_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 334.0
CSH2_k127_2577546_2 ABC-type tungstate transport system permease component-like protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000006128 228.0
CSH2_k127_2577546_3 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000001593 207.0
CSH2_k127_2577546_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000183 203.0
CSH2_k127_2577546_5 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000756 173.0
CSH2_k127_2577546_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000001138 153.0
CSH2_k127_2577546_7 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000003222 118.0
CSH2_k127_2577546_8 PKD domain - - - 0.00000000000000007206 95.0
CSH2_k127_2604274_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 520.0
CSH2_k127_2604274_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 454.0
CSH2_k127_2604274_10 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000001255 184.0
CSH2_k127_2604274_11 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000001618 124.0
CSH2_k127_2604274_12 domain protein K13735,K15125,K20276 - - 0.00000000000000000000000008128 126.0
CSH2_k127_2604274_13 ABC-type antimicrobial peptide transport system, permease component - - - 0.00000000000000004001 96.0
CSH2_k127_2604274_14 UbiE COQ5 methyltransferase K07755 - 2.1.1.137 0.00000000000000256 85.0
CSH2_k127_2604274_15 exo-alpha-(2->6)-sialidase activity - - - 0.00000005166 65.0
CSH2_k127_2604274_16 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000991 60.0
CSH2_k127_2604274_17 FtsX-like permease family K02004 - - 0.0004059 52.0
CSH2_k127_2604274_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 391.0
CSH2_k127_2604274_3 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 374.0
CSH2_k127_2604274_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 319.0
CSH2_k127_2604274_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 288.0
CSH2_k127_2604274_6 Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000009567 244.0
CSH2_k127_2604274_7 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000001069 220.0
CSH2_k127_2604274_8 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000004957 208.0
CSH2_k127_2604274_9 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000001203 205.0
CSH2_k127_2612799_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 460.0
CSH2_k127_2612799_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 336.0
CSH2_k127_2612799_10 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000005315 109.0
CSH2_k127_2612799_11 - - - - 0.0000000000000000000001067 103.0
CSH2_k127_2612799_12 PFAM Forkhead-associated protein - - - 0.000000000000000000001199 108.0
CSH2_k127_2612799_13 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000001911 110.0
CSH2_k127_2612799_14 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000001311 99.0
CSH2_k127_2612799_15 - - - - 0.000000000791 66.0
CSH2_k127_2612799_16 helix_turn_helix ASNC type - - - 0.00001054 57.0
CSH2_k127_2612799_17 domain, Protein - - - 0.00001565 57.0
CSH2_k127_2612799_2 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 314.0
CSH2_k127_2612799_3 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000003078 251.0
CSH2_k127_2612799_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000001844 237.0
CSH2_k127_2612799_5 Zn-dependent protease with chaperone function K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000001801 241.0
CSH2_k127_2612799_6 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000001273 205.0
CSH2_k127_2612799_7 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001536 174.0
CSH2_k127_2612799_8 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000000000000002159 150.0
CSH2_k127_2612799_9 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000009205 117.0
CSH2_k127_2645197_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000003157 269.0
CSH2_k127_2645197_1 Histidine kinase - - - 0.000001651 60.0
CSH2_k127_2691389_0 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 304.0
CSH2_k127_2691389_1 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000992 246.0
CSH2_k127_2691389_2 TrkA-C domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000714 225.0
CSH2_k127_2691389_3 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000007021 162.0
CSH2_k127_2691389_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000403 150.0
CSH2_k127_2701230_0 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 316.0
CSH2_k127_2701230_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000001223 238.0
CSH2_k127_2701230_2 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000000000000000188 181.0
CSH2_k127_2701230_3 Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000004454 97.0
CSH2_k127_2701230_4 Psort location CytoplasmicMembrane, score - - - 0.000000005381 66.0
CSH2_k127_2718048_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 484.0
CSH2_k127_2718048_1 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 449.0
CSH2_k127_2718048_10 Putative RNA methylase family UPF0020 K07446 - 2.1.1.213 0.00000000000000000000000000000000000000000000001689 183.0
CSH2_k127_2718048_11 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000003308 173.0
CSH2_k127_2718048_12 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000558 146.0
CSH2_k127_2718048_13 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000114 119.0
CSH2_k127_2718048_14 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.000000000006455 67.0
CSH2_k127_2718048_15 Major Facilitator Superfamily K08222 - - 0.000000003351 68.0
CSH2_k127_2718048_16 - - - - 0.00000004051 63.0
CSH2_k127_2718048_17 Acetyltransferase K03827 - - 0.000002014 57.0
CSH2_k127_2718048_2 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 440.0
CSH2_k127_2718048_3 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 437.0
CSH2_k127_2718048_4 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 347.0
CSH2_k127_2718048_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 316.0
CSH2_k127_2718048_6 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 299.0
CSH2_k127_2718048_7 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003854 272.0
CSH2_k127_2718048_8 Involved in the catabolism of quinolinic acid (QA) K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000001049 263.0
CSH2_k127_2718048_9 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000004331 214.0
CSH2_k127_2718507_0 Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000000000000000000000000000000006258 210.0
CSH2_k127_2718507_1 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000003645 200.0
CSH2_k127_2718507_2 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000002932 135.0
CSH2_k127_2718507_3 COG3209 Rhs family protein - - - 0.00000000004979 77.0
CSH2_k127_2718507_4 Carbohydrate binding module (family 6) - - - 0.00008569 56.0
CSH2_k127_2722102_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004623 271.0
CSH2_k127_2722102_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000005943 243.0
CSH2_k127_2722102_2 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000492 223.0
CSH2_k127_2722102_3 metallopeptidase activity K01126,K01181 - 3.1.4.46,3.2.1.8 0.000000000000003448 91.0
CSH2_k127_2722102_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000001037 89.0
CSH2_k127_2743287_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1744.0
CSH2_k127_2743287_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1279.0
CSH2_k127_2743287_10 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000008164 260.0
CSH2_k127_2743287_11 Participates in transcription termination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000005897 215.0
CSH2_k127_2743287_12 RNA-binding protein of the translin family K07477 - - 0.00000000000000000000000000000000000000000003144 169.0
CSH2_k127_2743287_13 archaeal Zn-finger protein - - - 0.00000000000000000000000000000000000000003216 159.0
CSH2_k127_2743287_14 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000003981 155.0
CSH2_k127_2743287_15 Methyltransferase domain K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.297 0.00000000000000000000000000000000002512 142.0
CSH2_k127_2743287_16 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000005849 142.0
CSH2_k127_2743287_17 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000005312 127.0
CSH2_k127_2743287_18 TraB family - - - 0.000000000000000000000000000002061 130.0
CSH2_k127_2743287_19 Domain of unknown function (DU1801) - - - 0.0000000000000000000008003 100.0
CSH2_k127_2743287_2 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 6.48e-256 865.0
CSH2_k127_2743287_20 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000000591 94.0
CSH2_k127_2743287_21 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000792 96.0
CSH2_k127_2743287_22 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.00000000000000000007515 91.0
CSH2_k127_2743287_23 Rhomboid family K19225 - 3.4.21.105 0.0000000000000004394 89.0
CSH2_k127_2743287_24 CARDB - - - 0.000005264 58.0
CSH2_k127_2743287_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 617.0
CSH2_k127_2743287_4 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 470.0
CSH2_k127_2743287_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 448.0
CSH2_k127_2743287_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 412.0
CSH2_k127_2743287_7 4Fe-4S single cluster domain K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 345.0
CSH2_k127_2743287_8 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003658 277.0
CSH2_k127_2743287_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000173 265.0
CSH2_k127_2767777_0 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 390.0
CSH2_k127_2767777_1 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 356.0
CSH2_k127_2767777_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005641 266.0
CSH2_k127_2767777_3 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000000004073 204.0
CSH2_k127_2767777_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000002987 106.0
CSH2_k127_2818500_0 ATP-grasp domain K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 359.0
CSH2_k127_2818500_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 341.0
CSH2_k127_2818500_2 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.0000000000000000000000000000000000005284 147.0
CSH2_k127_2818500_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000002578 123.0
CSH2_k127_2818500_4 COG1100 GTPase SAR1 and related small G - - - 0.000000000000000000000000003921 121.0
CSH2_k127_2818500_5 OmpA family - - - 0.00000000023 69.0
CSH2_k127_291292_0 DNA polymerase type-B family K02319 - 2.7.7.7 2.441e-254 807.0
CSH2_k127_291292_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 3.793e-228 726.0
CSH2_k127_291292_10 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 378.0
CSH2_k127_291292_11 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 378.0
CSH2_k127_291292_12 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 326.0
CSH2_k127_291292_13 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 324.0
CSH2_k127_291292_14 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 306.0
CSH2_k127_291292_15 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001357 281.0
CSH2_k127_291292_16 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001523 271.0
CSH2_k127_291292_17 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006765 270.0
CSH2_k127_291292_18 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001718 272.0
CSH2_k127_291292_19 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001555 254.0
CSH2_k127_291292_2 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 562.0
CSH2_k127_291292_20 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000455 250.0
CSH2_k127_291292_21 Helix-hairpin-helix motif K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000001989 234.0
CSH2_k127_291292_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003719 229.0
CSH2_k127_291292_23 TIGRFAM geranylgeranyl reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001915 235.0
CSH2_k127_291292_24 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000462 225.0
CSH2_k127_291292_25 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000001303 216.0
CSH2_k127_291292_26 K homology RNA-binding domain K06961 - - 0.000000000000000000000000000000000000000000000000002772 187.0
CSH2_k127_291292_27 - - - - 0.0000000000000000000000000000000000000000000000000342 198.0
CSH2_k127_291292_28 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.000000000000000000000000000000000000000000002038 176.0
CSH2_k127_291292_29 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000002291 173.0
CSH2_k127_291292_3 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 544.0
CSH2_k127_291292_30 Clostripain family - - - 0.00000000000000000000000000000000000000006106 168.0
CSH2_k127_291292_31 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000002991 154.0
CSH2_k127_291292_32 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000000003897 149.0
CSH2_k127_291292_33 PFAM response regulator receiver K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000008703 135.0
CSH2_k127_291292_34 RNA polymerase subunit 9 K03057 - - 0.00000000000000000000000000005823 118.0
CSH2_k127_291292_35 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.0000000000000000000000000001438 118.0
CSH2_k127_291292_36 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000000006267 100.0
CSH2_k127_291292_37 - - - - 0.0000000000000000007611 94.0
CSH2_k127_291292_38 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000000002877 88.0
CSH2_k127_291292_39 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000002948 96.0
CSH2_k127_291292_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 522.0
CSH2_k127_291292_40 Sulfite exporter TauE/SafE K07090 - - 0.000000000001211 78.0
CSH2_k127_291292_41 methylphosphotriester-DNA alkyltransferase (AraC XylS family) K13652 - - 0.00000000002002 70.0
CSH2_k127_291292_42 - - - - 0.000000281 63.0
CSH2_k127_291292_43 Protein of unknown function (DUF835) - - - 0.000003515 57.0
CSH2_k127_291292_45 PFAM Dinitrogenase iron-molybdenum cofactor - - - 0.00003431 51.0
CSH2_k127_291292_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 520.0
CSH2_k127_291292_6 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 486.0
CSH2_k127_291292_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 445.0
CSH2_k127_291292_8 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 435.0
CSH2_k127_291292_9 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 385.0
CSH2_k127_3030742_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 492.0
CSH2_k127_3030742_1 Double zinc ribbon - - - 0.000000000000000000000000000000000007641 160.0
CSH2_k127_3030742_2 DnaB-like helicase C terminal domain - - - 0.0000000000000000000001484 106.0
CSH2_k127_3030742_3 virion core protein, lumpy skin disease virus - - - 0.000149 53.0
CSH2_k127_3030842_0 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002416 257.0
CSH2_k127_3030842_1 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000000000000000193 220.0
CSH2_k127_3030842_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000003645 187.0
CSH2_k127_3030842_3 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000007186 122.0
CSH2_k127_3030842_4 Sugar (and other) transporter - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000001401 63.0
CSH2_k127_3136885_0 Citrate transporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 464.0
CSH2_k127_3136885_1 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 417.0
CSH2_k127_3136885_2 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 416.0
CSH2_k127_3136885_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 370.0
CSH2_k127_3136885_4 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000001034 179.0
CSH2_k127_3136885_5 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000009962 142.0
CSH2_k127_3219594_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002567 265.0
CSH2_k127_3219594_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000001539 259.0
CSH2_k127_3219594_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000002331 248.0
CSH2_k127_3219594_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000001329 239.0
CSH2_k127_3219594_4 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family - - - 0.000000000000000000000000000000000000000000000000000003922 200.0
CSH2_k127_3219594_5 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000002616 189.0
CSH2_k127_3219594_6 domain protein K13735,K15125,K20276 - - 0.0000000000000000000002787 115.0
CSH2_k127_3289169_0 Belongs to the arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 293.0
CSH2_k127_3289169_1 - - - - 0.00000000000000000000000000000000000000000003253 175.0
CSH2_k127_3289169_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000004305 152.0
CSH2_k127_3289169_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000006406 124.0
CSH2_k127_3289169_4 protein conserved in archaea - - - 0.0000000000000000000000001385 109.0
CSH2_k127_3325376_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 416.0
CSH2_k127_3325376_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 378.0
CSH2_k127_3325376_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000005378 227.0
CSH2_k127_3325376_11 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000002476 208.0
CSH2_k127_3325376_12 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000001415 201.0
CSH2_k127_3325376_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000106 183.0
CSH2_k127_3325376_14 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.00000000000000000000000000000000002956 146.0
CSH2_k127_3325376_15 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000006513 76.0
CSH2_k127_3325376_2 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 375.0
CSH2_k127_3325376_3 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 344.0
CSH2_k127_3325376_4 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 331.0
CSH2_k127_3325376_5 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 319.0
CSH2_k127_3325376_6 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000001991 251.0
CSH2_k127_3325376_7 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000002198 245.0
CSH2_k127_3325376_8 Mechanosensitive ion channel K03442,K05802,K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000007199 250.0
CSH2_k127_3325376_9 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000009216 242.0
CSH2_k127_3331989_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 582.0
CSH2_k127_3331989_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 558.0
CSH2_k127_3331989_10 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000000000000000006444 228.0
CSH2_k127_3331989_11 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000058 140.0
CSH2_k127_3331989_12 glucosylceramidase activity - - - 0.0000000000000000000000000000002362 126.0
CSH2_k127_3331989_13 4Fe-4S binding domain - - - 0.000000000000000000000000000001442 127.0
CSH2_k127_3331989_14 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000006714 99.0
CSH2_k127_3331989_15 PFAM 4-vinyl reductase, 4VR K07013 - - 0.000000000000000000006441 97.0
CSH2_k127_3331989_16 Roadblock LC7 family protein K07131 - - 0.0000000000000000002554 91.0
CSH2_k127_3331989_17 Ribosomal protein L37e K02922 - - 0.00000000000000003524 81.0
CSH2_k127_3331989_18 ABC-2 family transporter protein K01992 - - 0.0000000000000006276 87.0
CSH2_k127_3331989_19 - - - - 0.000000001697 61.0
CSH2_k127_3331989_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 455.0
CSH2_k127_3331989_21 2TM domain - - - 0.0000008746 52.0
CSH2_k127_3331989_22 - - - - 0.000003276 55.0
CSH2_k127_3331989_23 helix_turn_helix ASNC type K03718 - - 0.00003309 55.0
CSH2_k127_3331989_24 - - - - 0.0007209 48.0
CSH2_k127_3331989_3 Arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 383.0
CSH2_k127_3331989_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01464,K01465,K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.2,3.5.2.3,3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 349.0
CSH2_k127_3331989_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 296.0
CSH2_k127_3331989_6 ATPase activity K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000852 276.0
CSH2_k127_3331989_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002009 258.0
CSH2_k127_3331989_8 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001365 250.0
CSH2_k127_3331989_9 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000005691 241.0
CSH2_k127_3413279_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 426.0
CSH2_k127_3413279_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000002769 206.0
CSH2_k127_3413279_2 TIGRFAM methyltransferase FkbM - - - 0.00000000000000000000000000002247 127.0
CSH2_k127_3413279_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000001267 100.0
CSH2_k127_3413279_5 tRNA (uracil) methyltransferase activity K10770 GO:0000049,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008198,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016491,GO:0016604,GO:0016705,GO:0016706,GO:0016740,GO:0016741,GO:0030488,GO:0031974,GO:0031981,GO:0032259,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051213,GO:0051716,GO:0055114,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.229 0.00002536 53.0
CSH2_k127_3501617_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1485.0
CSH2_k127_3501617_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 9.145e-254 794.0
CSH2_k127_3501617_10 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 359.0
CSH2_k127_3501617_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 340.0
CSH2_k127_3501617_12 FAD binding domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 347.0
CSH2_k127_3501617_13 Rad51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 330.0
CSH2_k127_3501617_14 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 350.0
CSH2_k127_3501617_15 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 323.0
CSH2_k127_3501617_16 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 299.0
CSH2_k127_3501617_17 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 306.0
CSH2_k127_3501617_18 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 299.0
CSH2_k127_3501617_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005222 280.0
CSH2_k127_3501617_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 3.742e-240 750.0
CSH2_k127_3501617_20 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003597 257.0
CSH2_k127_3501617_21 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000479 254.0
CSH2_k127_3501617_22 ATP-binding protein K16786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000365 256.0
CSH2_k127_3501617_23 PFAM ABC transporter K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000005945 243.0
CSH2_k127_3501617_24 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000006471 225.0
CSH2_k127_3501617_25 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000000000000000000000000000002263 228.0
CSH2_k127_3501617_26 Radical SAM domain protein K09711 - - 0.000000000000000000000000000000000000000000000000000000463 203.0
CSH2_k127_3501617_27 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000000006061 184.0
CSH2_k127_3501617_28 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000341 176.0
CSH2_k127_3501617_29 Signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000000000000000000001839 174.0
CSH2_k127_3501617_3 MCM OB domain K10726 - - 1.175e-215 690.0
CSH2_k127_3501617_30 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000239 166.0
CSH2_k127_3501617_31 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000003649 160.0
CSH2_k127_3501617_32 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000001877 154.0
CSH2_k127_3501617_33 NMD3 family K07562 - - 0.0000000000000000000000000000000000000413 156.0
CSH2_k127_3501617_34 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000000002324 115.0
CSH2_k127_3501617_35 Protein of unknown function (DUF424) K09148 - - 0.0000000000000000000000006194 109.0
CSH2_k127_3501617_36 RNA binding K09736 - - 0.0000000000000000000000006239 108.0
CSH2_k127_3501617_37 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000001276 107.0
CSH2_k127_3501617_38 CAAX protease self-immunity - - - 0.000000000000000000000001452 119.0
CSH2_k127_3501617_39 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000005772 108.0
CSH2_k127_3501617_4 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 523.0
CSH2_k127_3501617_40 Belongs to the peptidase S8 family - - - 0.0000000000000000008276 101.0
CSH2_k127_3501617_41 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000004836 85.0
CSH2_k127_3501617_42 PFAM ATP synthase subunit C K02124 - - 0.00000000000006255 74.0
CSH2_k127_3501617_43 RDD family - - - 0.000000000001157 74.0
CSH2_k127_3501617_44 PFAM Ribosomal LX protein K02944 - - 0.000000000008008 68.0
CSH2_k127_3501617_45 membrane-associated protein domain - - - 0.000001376 57.0
CSH2_k127_3501617_46 - - - - 0.00009984 53.0
CSH2_k127_3501617_47 Pfam:DUF1628 - - - 0.0001 51.0
CSH2_k127_3501617_5 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 481.0
CSH2_k127_3501617_6 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 469.0
CSH2_k127_3501617_7 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 435.0
CSH2_k127_3501617_8 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 432.0
CSH2_k127_3501617_9 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 366.0
CSH2_k127_3544787_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 3.054e-254 811.0
CSH2_k127_3544787_1 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 580.0
CSH2_k127_3544787_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000004624 246.0
CSH2_k127_3544787_11 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000006342 197.0
CSH2_k127_3544787_12 - - - - 0.000000000000000000000000000000000000000000000000005793 189.0
CSH2_k127_3544787_13 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000001101 186.0
CSH2_k127_3544787_14 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000000000004997 146.0
CSH2_k127_3544787_15 - - - - 0.00000000000000000000000001816 123.0
CSH2_k127_3544787_16 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.000000000000000000000000021 113.0
CSH2_k127_3544787_17 cheY-homologous receiver domain - - - 0.0000000000000000000001366 109.0
CSH2_k127_3544787_18 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000005181 95.0
CSH2_k127_3544787_19 - - - - 0.000000000000003334 86.0
CSH2_k127_3544787_2 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 552.0
CSH2_k127_3544787_20 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000006197 90.0
CSH2_k127_3544787_21 Domain of unknown function (DUF749) - - - 0.000000007509 60.0
CSH2_k127_3544787_22 - - - - 0.00000004266 58.0
CSH2_k127_3544787_23 Transcriptional regulator - - - 0.000006619 58.0
CSH2_k127_3544787_24 Gnat family K03828 - - 0.0008344 51.0
CSH2_k127_3544787_3 COG0277 FAD FMN-containing dehydrogenases K00102,K00104,K06911 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 539.0
CSH2_k127_3544787_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 378.0
CSH2_k127_3544787_5 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 350.0
CSH2_k127_3544787_6 PFAM Peptidase family M20 M25 M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 326.0
CSH2_k127_3544787_7 SMART ATPase, AAA type, core K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000876 272.0
CSH2_k127_3544787_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005137 266.0
CSH2_k127_3544787_9 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004334 258.0
CSH2_k127_3549125_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 6.917e-275 866.0
CSH2_k127_3549125_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 365.0
CSH2_k127_3549125_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 336.0
CSH2_k127_3549125_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000001412 234.0
CSH2_k127_3549125_4 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000001339 215.0
CSH2_k127_3549125_5 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000002828 184.0
CSH2_k127_3549125_6 PRC-barrel domain - - - 0.0000000000000000000000000111 110.0
CSH2_k127_3549125_7 oxidoreductase subunit delta K00171 - 1.2.7.1 0.00000000000000000000011 109.0
CSH2_k127_3549125_8 PFAM Tetratricopeptide repeat - - - 0.000000000000000001461 100.0
CSH2_k127_3549125_9 PFAM Acetyltransferase (GNAT) family - - - 0.0001591 47.0
CSH2_k127_3674990_0 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 422.0
CSH2_k127_3674990_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 413.0
CSH2_k127_3674990_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003858 273.0
CSH2_k127_3674990_11 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 258.0
CSH2_k127_3674990_12 ICC-like phosphoesterases K06953 - - 0.000000000000000000000000000000000000000000000000000001939 200.0
CSH2_k127_3674990_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000009914 191.0
CSH2_k127_3674990_14 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000009722 177.0
CSH2_k127_3674990_15 Ribosomal protein S8e K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000000000004214 149.0
CSH2_k127_3674990_16 Uncharacterized ArCR, COG1888 K09732 - - 0.00000000000000000000000000000006509 126.0
CSH2_k127_3674990_17 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.000000000000000000000002649 107.0
CSH2_k127_3674990_18 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000002628 90.0
CSH2_k127_3674990_19 binds to the 23S rRNA K02921 - - 0.000000000000004533 79.0
CSH2_k127_3674990_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 407.0
CSH2_k127_3674990_20 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.000000000002034 72.0
CSH2_k127_3674990_21 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.000000000002801 68.0
CSH2_k127_3674990_22 Transcription factor Pcc1 K09741 - - 0.0000009226 53.0
CSH2_k127_3674990_23 deoxyhypusine monooxygenase activity - - - 0.00009557 54.0
CSH2_k127_3674990_24 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0001277 49.0
CSH2_k127_3674990_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 391.0
CSH2_k127_3674990_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 364.0
CSH2_k127_3674990_5 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 339.0
CSH2_k127_3674990_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 325.0
CSH2_k127_3674990_7 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 309.0
CSH2_k127_3674990_8 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 301.0
CSH2_k127_3674990_9 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 296.0
CSH2_k127_3787763_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 494.0
CSH2_k127_3787763_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 412.0
CSH2_k127_3787763_2 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000000003191 204.0
CSH2_k127_3789666_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 1.904e-219 694.0
CSH2_k127_3789666_1 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 2.65e-203 642.0
CSH2_k127_3789666_10 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 373.0
CSH2_k127_3789666_11 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 370.0
CSH2_k127_3789666_12 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 366.0
CSH2_k127_3789666_13 CoA binding domain K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 363.0
CSH2_k127_3789666_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 311.0
CSH2_k127_3789666_15 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 314.0
CSH2_k127_3789666_16 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 301.0
CSH2_k127_3789666_17 PFAM Metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 297.0
CSH2_k127_3789666_18 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003697 272.0
CSH2_k127_3789666_19 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004054 260.0
CSH2_k127_3789666_2 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 598.0
CSH2_k127_3789666_20 oxidoreductase activity K03924,K04748,K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000009965 256.0
CSH2_k127_3789666_21 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000002993 240.0
CSH2_k127_3789666_22 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000005459 228.0
CSH2_k127_3789666_23 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000001028 213.0
CSH2_k127_3789666_24 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.0000000000000000000000000000000000000000000000000000000001205 213.0
CSH2_k127_3789666_25 peptidase activity, acting on L-amino acid peptides K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000000000000000001307 224.0
CSH2_k127_3789666_26 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000258 208.0
CSH2_k127_3789666_27 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000006168 195.0
CSH2_k127_3789666_28 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000002418 181.0
CSH2_k127_3789666_29 PFAM amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000004934 182.0
CSH2_k127_3789666_3 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 424.0
CSH2_k127_3789666_30 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000123 188.0
CSH2_k127_3789666_31 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000003323 169.0
CSH2_k127_3789666_32 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000006246 176.0
CSH2_k127_3789666_33 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000001989 166.0
CSH2_k127_3789666_34 Uncharacterised protein family (UPF0179) K09730 - - 0.000000000000000000000000000000000000001192 151.0
CSH2_k127_3789666_35 PAC2 family K06869 - - 0.000000000000000000000000000000000000002292 156.0
CSH2_k127_3789666_36 Flavodoxin - - - 0.000000000000000000000000000000000000002807 151.0
CSH2_k127_3789666_37 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000003025 162.0
CSH2_k127_3789666_38 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000005161 164.0
CSH2_k127_3789666_39 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000001333 159.0
CSH2_k127_3789666_4 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 416.0
CSH2_k127_3789666_40 Calcineurin-like phosphoesterase superfamily domain K06953 - - 0.00000000000000000000000000000000000002072 154.0
CSH2_k127_3789666_41 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000002613 158.0
CSH2_k127_3789666_42 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000006336 143.0
CSH2_k127_3789666_43 Flavodoxin-like fold - - - 0.0000000000000000000000000000000003911 138.0
CSH2_k127_3789666_44 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.0000000000000000000000000000008682 142.0
CSH2_k127_3789666_45 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000007581 137.0
CSH2_k127_3789666_46 Cyclophilin-like K09143 - - 0.0000000000000000000000000001738 119.0
CSH2_k127_3789666_47 COG1100 GTPase SAR1 and related small G - - - 0.0000000000000000000000000002146 123.0
CSH2_k127_3789666_48 Pfam:DUF552 K09152 - - 0.00000000000000000000000001119 114.0
CSH2_k127_3789666_49 Response regulator receiver domain - - - 0.0000000000000000000000001643 109.0
CSH2_k127_3789666_5 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 412.0
CSH2_k127_3789666_50 SMART Excinuclease ABC C subunit domain protein - - - 0.0000000000000000000000004082 111.0
CSH2_k127_3789666_51 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.000000000000000000000004243 110.0
CSH2_k127_3789666_52 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000001091 100.0
CSH2_k127_3789666_53 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000009739 111.0
CSH2_k127_3789666_54 DNA-binding transcription factor activity K18297 - - 0.0000000000000000000009485 105.0
CSH2_k127_3789666_55 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000004795 104.0
CSH2_k127_3789666_56 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000006836 92.0
CSH2_k127_3789666_57 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000001012 93.0
CSH2_k127_3789666_58 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000001182 94.0
CSH2_k127_3789666_59 Protein of unknown function (DUF1614) - - - 0.000000000000000006397 93.0
CSH2_k127_3789666_6 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 391.0
CSH2_k127_3789666_60 histone H2A K63-linked ubiquitination - - - 0.000000000000000009192 96.0
CSH2_k127_3789666_61 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000009754 89.0
CSH2_k127_3789666_62 MoaE protein K21142 - 2.8.1.12 0.0000000000000002705 81.0
CSH2_k127_3789666_63 - - - - 0.0000000000000211 77.0
CSH2_k127_3789666_64 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000002355 78.0
CSH2_k127_3789666_65 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000359 81.0
CSH2_k127_3789666_66 Acetyltransferase (GNAT) domain - - - 0.0000000000003093 75.0
CSH2_k127_3789666_67 COG1522 Transcriptional regulators - - - 0.0000000000003541 81.0
CSH2_k127_3789666_68 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000001231 74.0
CSH2_k127_3789666_69 Acetyltransferase (GNAT) domain - - - 0.0000000003075 70.0
CSH2_k127_3789666_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 387.0
CSH2_k127_3789666_70 Acetyltransferase (GNAT) family - - - 0.0000000006081 67.0
CSH2_k127_3789666_71 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.000000004255 68.0
CSH2_k127_3789666_72 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000352 65.0
CSH2_k127_3789666_73 PFAM Rubrerythrin - - - 0.00000006912 61.0
CSH2_k127_3789666_74 Major Facilitator Superfamily - - - 0.000000103 64.0
CSH2_k127_3789666_75 Double zinc ribbon - - - 0.000001175 55.0
CSH2_k127_3789666_76 diguanylate cyclase - - - 0.000001884 61.0
CSH2_k127_3789666_77 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000009878 53.0
CSH2_k127_3789666_78 Isochorismatase family - - - 0.00003435 52.0
CSH2_k127_3789666_79 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00007105 46.0
CSH2_k127_3789666_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 378.0
CSH2_k127_3789666_80 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0002915 53.0
CSH2_k127_3789666_81 Double zinc ribbon - - - 0.0005457 50.0
CSH2_k127_3789666_9 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 364.0
CSH2_k127_393403_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.321e-273 869.0
CSH2_k127_393403_1 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 466.0
CSH2_k127_393403_10 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002838 197.0
CSH2_k127_393403_11 Peptidase family M28 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000001075 176.0
CSH2_k127_393403_12 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000001982 158.0
CSH2_k127_393403_13 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002716 113.0
CSH2_k127_393403_14 Protein of unknown function (DUF835) - - - 0.00000000000001025 81.0
CSH2_k127_393403_15 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.00000000000004352 74.0
CSH2_k127_393403_16 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 - - - 0.0000000000002133 76.0
CSH2_k127_393403_17 - - - - 0.0000000000007908 73.0
CSH2_k127_393403_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 447.0
CSH2_k127_393403_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 342.0
CSH2_k127_393403_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 329.0
CSH2_k127_393403_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 313.0
CSH2_k127_393403_6 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 296.0
CSH2_k127_393403_7 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 297.0
CSH2_k127_393403_8 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003687 275.0
CSH2_k127_393403_9 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000007246 211.0
CSH2_k127_4185129_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 438.0
CSH2_k127_4185129_1 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 356.0
CSH2_k127_4185129_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003104 286.0
CSH2_k127_4185129_3 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000003405 210.0
CSH2_k127_4185129_4 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000001468 188.0
CSH2_k127_4185129_5 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000002735 182.0
CSH2_k127_4185129_6 Transcriptional regulator K07730 - - 0.000000000000000000000002727 112.0
CSH2_k127_4185129_7 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000002762 79.0
CSH2_k127_4243341_0 aminopeptidase activity K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 321.0
CSH2_k127_4243341_1 Protein of unknown function (DUF454) K09790 - - 0.0000000000000000000000000000000003743 136.0
CSH2_k127_4243341_2 - K21429 - - 0.0000000000000000000000371 108.0
CSH2_k127_4243341_3 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000001598 69.0
CSH2_k127_4243341_4 Clostripain family - - - 0.000000003155 70.0
CSH2_k127_4243341_5 membrane-associated protein domain - - - 0.0000003951 59.0
CSH2_k127_4243341_6 regulation of response to stimulus K01387,K01771 - 3.4.24.3,4.6.1.13 0.0002451 52.0
CSH2_k127_4280589_0 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.0000000000000000000000001455 125.0
CSH2_k127_4280589_1 - - - - 0.0000000000000000003581 93.0
CSH2_k127_4335794_0 helicase superfamily c-terminal domain K03724 - - 4.556e-306 962.0
CSH2_k127_4335794_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 533.0
CSH2_k127_4335794_10 - - - - 0.0000000000000000000000000000000000001885 151.0
CSH2_k127_4335794_11 Probable zinc-ribbon domain - - - 0.000000000000005088 79.0
CSH2_k127_4335794_12 Arginase family - - - 0.00003872 46.0
CSH2_k127_4335794_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 475.0
CSH2_k127_4335794_3 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 469.0
CSH2_k127_4335794_4 Thioredoxin domain K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 346.0
CSH2_k127_4335794_5 PFAM Pyruvate carboxyltransferase K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 311.0
CSH2_k127_4335794_6 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001403 283.0
CSH2_k127_4335794_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000002323 215.0
CSH2_k127_4335794_8 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.00000000000000000000000000000000000000000000000004799 183.0
CSH2_k127_4335794_9 Sodium hydrogen exchanger K11105 - - 0.00000000000000000000000000000000000000000001065 179.0
CSH2_k127_4372726_0 Cobalamin B12-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 565.0
CSH2_k127_4372726_1 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 421.0
CSH2_k127_4372726_11 - - - - 0.000000001512 64.0
CSH2_k127_4372726_12 virion core protein, lumpy skin disease virus - - - 0.0002769 49.0
CSH2_k127_4372726_2 Cysteine-rich domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 370.0
CSH2_k127_4372726_3 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003186 297.0
CSH2_k127_4372726_4 Biotin-protein ligase, N terminal - - - 0.0000000000000000000000000000000000000000000004487 180.0
CSH2_k127_4372726_5 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000001436 126.0
CSH2_k127_4372726_6 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000007671 122.0
CSH2_k127_4372726_7 Belongs to the peptidase S8 family - - - 0.00000000000000000000005762 112.0
CSH2_k127_4372726_8 - - - - 0.00000000001796 74.0
CSH2_k127_4372726_9 denitrification pathway - - - 0.00000000004006 74.0
CSH2_k127_4510632_0 GXGXG motif - - - 8.388e-286 902.0
CSH2_k127_4510632_1 Glutamate synthase - - - 1.062e-194 619.0
CSH2_k127_4510632_10 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000000000002263 112.0
CSH2_k127_4510632_11 - - - - 0.00000000000000000000001475 107.0
CSH2_k127_4510632_12 Tetratricopeptide repeat - - - 0.0000000000000000001456 96.0
CSH2_k127_4510632_13 PFAM glutaredoxin - - - 0.000000000000001003 80.0
CSH2_k127_4510632_14 LGN motif, putative GEFs specific for G-alpha GTPases K15837,K15839 GO:0000132,GO:0000139,GO:0000226,GO:0000278,GO:0001709,GO:0001965,GO:0003674,GO:0005092,GO:0005096,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005794,GO:0005829,GO:0005886,GO:0005938,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007163,GO:0007275,GO:0007399,GO:0007400,GO:0007405,GO:0008047,GO:0008104,GO:0008150,GO:0008277,GO:0008283,GO:0008356,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009987,GO:0010506,GO:0010508,GO:0010646,GO:0012505,GO:0014016,GO:0014017,GO:0016020,GO:0016043,GO:0016239,GO:0016241,GO:0017145,GO:0019222,GO:0019904,GO:0022008,GO:0022402,GO:0023051,GO:0030010,GO:0030154,GO:0030234,GO:0030695,GO:0031090,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031974,GO:0031981,GO:0031984,GO:0032091,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0034260,GO:0036445,GO:0040001,GO:0042175,GO:0043085,GO:0043086,GO:0043087,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0043547,GO:0044092,GO:0044093,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0045165,GO:0045167,GO:0045175,GO:0045177,GO:0045179,GO:0045185,GO:0048103,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048699,GO:0048731,GO:0048856,GO:0048863,GO:0048865,GO:0048867,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050795,GO:0051098,GO:0051099,GO:0051100,GO:0051179,GO:0051234,GO:0051235,GO:0051293,GO:0051294,GO:0051301,GO:0051336,GO:0051345,GO:0051346,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0055057,GO:0055059,GO:0060259,GO:0060589,GO:0061351,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0071840,GO:0071944,GO:0072089,GO:0098588,GO:0098722,GO:0098772,GO:0098791,GO:0098827,GO:0099568,GO:0099738,GO:1902850,GO:1903047,GO:1904424,GO:1905097,GO:1905098 - 0.00000000000000663 87.0
CSH2_k127_4510632_15 PFAM 4Fe-4S - - - 0.000000000006455 67.0
CSH2_k127_4510632_16 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000005049 54.0
CSH2_k127_4510632_2 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 579.0
CSH2_k127_4510632_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 326.0
CSH2_k127_4510632_4 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000004991 214.0
CSH2_k127_4510632_5 PIN domain - - - 0.000000000000000000000000000000000000000000000000002128 199.0
CSH2_k127_4510632_6 GAF domain - - - 0.00000000000000000000000000000000000000000000001128 192.0
CSH2_k127_4510632_7 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000000000000000001074 140.0
CSH2_k127_4510632_9 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000008112 114.0
CSH2_k127_4531577_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 1.602e-203 657.0
CSH2_k127_4531577_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 7.574e-203 651.0
CSH2_k127_4531577_10 sequence-specific DNA binding - - - 0.00003019 56.0
CSH2_k127_4531577_11 benzodiazepine receptor binding K11771,K17591,K19922,K20478 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0005938,GO:0006996,GO:0007010,GO:0007154,GO:0007267,GO:0007268,GO:0007274,GO:0008150,GO:0009987,GO:0016043,GO:0023052,GO:0030863,GO:0030865,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044448,GO:0044456,GO:0044464,GO:0045202,GO:0048786,GO:0048788,GO:0048789,GO:0050808,GO:0071840,GO:0071944,GO:0097458,GO:0098793,GO:0098831,GO:0098916,GO:0099536,GO:0099537,GO:0099568,GO:0099569,GO:0099738,GO:1990709 - 0.0002246 55.0
CSH2_k127_4531577_2 DNA polymerase X family K02347,K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 552.0
CSH2_k127_4531577_3 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.00000000000000000000000000000000000000000000000000000000000000000000001579 261.0
CSH2_k127_4531577_4 B12 binding domain K14084 - - 0.00000000000000000000000000000000000000000000000000008013 195.0
CSH2_k127_4531577_5 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000001915 171.0
CSH2_k127_4531577_6 Beta-lactamase enzyme family K01467,K17836 - 3.5.2.6 0.0000000000000000000000000000000001843 146.0
CSH2_k127_4531577_7 serine threonine protein kinase - - - 0.000000000000000000003644 102.0
CSH2_k127_4531577_8 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091,K01838,K07025 - 3.1.3.18,5.4.2.6 0.0000000000000000001673 97.0
CSH2_k127_4531577_9 PAS domain K02488 - 2.7.7.65 0.000000000000001323 84.0
CSH2_k127_4632604_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1041.0
CSH2_k127_4632604_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 604.0
CSH2_k127_4632604_10 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.0000000000000000000000000000000000005576 142.0
CSH2_k127_4632604_11 EamA-like transporter family - - - 0.000000000000000000000000000000002982 139.0
CSH2_k127_4632604_12 Protein of unknown function (DUF1616) - - - 0.000000000000000000000000002866 118.0
CSH2_k127_4632604_13 TIGRFAM C_GCAxxG_C_C family protein - - - 0.0000000000000000009492 91.0
CSH2_k127_4632604_14 - - - - 0.00007002 48.0
CSH2_k127_4632604_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 555.0
CSH2_k127_4632604_3 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 315.0
CSH2_k127_4632604_4 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000002707 234.0
CSH2_k127_4632604_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000002322 237.0
CSH2_k127_4632604_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000002027 237.0
CSH2_k127_4632604_7 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000004394 228.0
CSH2_k127_4632604_8 nitroreductase - - - 0.000000000000000000000000000000000000000000000152 173.0
CSH2_k127_4632604_9 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000001693 161.0
CSH2_k127_4685791_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 596.0
CSH2_k127_4685791_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 430.0
CSH2_k127_4685791_10 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000005648 192.0
CSH2_k127_4685791_11 SMART MCP methyltransferase, CheR-type K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000008236 190.0
CSH2_k127_4685791_12 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000001759 190.0
CSH2_k127_4685791_13 thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000009791 162.0
CSH2_k127_4685791_14 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000004246 145.0
CSH2_k127_4685791_15 Chemotaxis protein cheY K03413 - - 0.000000000000000000000000000000325 132.0
CSH2_k127_4685791_16 Acetolactate synthase small K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000001096 118.0
CSH2_k127_4685791_17 PFAM CBS domain containing protein - - - 0.000000000000000000000000001159 118.0
CSH2_k127_4685791_18 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000001245 118.0
CSH2_k127_4685791_19 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.0000000000000000000002236 102.0
CSH2_k127_4685791_2 Chemotaxis protein CheA K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 424.0
CSH2_k127_4685791_20 chemotaxis protein K03410 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - 0.000000000000000000005859 101.0
CSH2_k127_4685791_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 401.0
CSH2_k127_4685791_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 349.0
CSH2_k127_4685791_5 PFAM isocitrate isopropylmalate dehydrogenase K10978 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 310.0
CSH2_k127_4685791_6 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 304.0
CSH2_k127_4685791_7 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000004339 273.0
CSH2_k127_4685791_8 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001318 245.0
CSH2_k127_4685791_9 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000001831 239.0
CSH2_k127_4698222_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 488.0
CSH2_k127_4698222_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 487.0
CSH2_k127_4698222_10 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 307.0
CSH2_k127_4698222_11 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 294.0
CSH2_k127_4698222_12 Oxidoreductase domain protein K18855 - 1.1.1.374 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 294.0
CSH2_k127_4698222_13 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 293.0
CSH2_k127_4698222_14 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001864 287.0
CSH2_k127_4698222_15 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001869 264.0
CSH2_k127_4698222_16 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000000000000124 221.0
CSH2_k127_4698222_17 PFAM DoxX family protein K16937 - 1.8.5.2 0.00000000000000000000000000000000000000000000000000000000002407 209.0
CSH2_k127_4698222_18 Iron permease FTR1 K07243 - - 0.000000000000000000000000000000000000000000000000000001254 202.0
CSH2_k127_4698222_19 - - - - 0.00000000000000000000000000000000000000000000000000001591 194.0
CSH2_k127_4698222_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 433.0
CSH2_k127_4698222_20 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.0000000000000000000000000000000000000000000000007737 184.0
CSH2_k127_4698222_21 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000009922 159.0
CSH2_k127_4698222_22 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000000000000000000000003511 147.0
CSH2_k127_4698222_23 EamA-like transporter family - - - 0.000000000000000000000000000004352 131.0
CSH2_k127_4698222_24 Methyltransferase type 12 - - - 0.00000000000000000000000007803 118.0
CSH2_k127_4698222_25 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000008187 116.0
CSH2_k127_4698222_26 EamA-like transporter family - - - 0.000000000000000000000002352 114.0
CSH2_k127_4698222_27 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000001056 117.0
CSH2_k127_4698222_28 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.0000000000000000000002158 100.0
CSH2_k127_4698222_29 saccharopine dehydrogenase activity - - - 0.00000000000000000003236 102.0
CSH2_k127_4698222_3 Aminotransferase class-III K00823,K03918,K20428 - 2.6.1.19,2.6.1.33,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 417.0
CSH2_k127_4698222_30 TIGRFAM iron-sulfur cluster binding protein K18979 - 1.17.99.6 0.0000000000000000003057 97.0
CSH2_k127_4698222_31 Belongs to the UPF0434 family - - - 0.0000000000000000123 87.0
CSH2_k127_4698222_32 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000003099 80.0
CSH2_k127_4698222_33 Predicted membrane protein (DUF2085) - - - 0.000000000000006341 83.0
CSH2_k127_4698222_34 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000001186 80.0
CSH2_k127_4698222_35 Circadian clock protein KaiC - - - 0.0000000002041 70.0
CSH2_k127_4698222_37 acetyltransferase K17840 - 2.3.1.59 0.00000001823 63.0
CSH2_k127_4698222_38 PFAM amino acid-binding ACT domain protein - - - 0.00000009795 59.0
CSH2_k127_4698222_39 Calcineurin-like phosphoesterase superfamily domain K03651 - 3.1.4.53 0.00008891 54.0
CSH2_k127_4698222_4 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 391.0
CSH2_k127_4698222_40 - - - - 0.0002171 48.0
CSH2_k127_4698222_41 membrane - - - 0.0002469 51.0
CSH2_k127_4698222_42 Protein of unknown function (DUF3667) - - - 0.0006055 49.0
CSH2_k127_4698222_5 PFAM elongation factor Tu domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 364.0
CSH2_k127_4698222_6 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 323.0
CSH2_k127_4698222_7 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 327.0
CSH2_k127_4698222_8 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 317.0
CSH2_k127_4698222_9 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 307.0
CSH2_k127_4775473_0 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 470.0
CSH2_k127_4775473_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 419.0
CSH2_k127_4775473_10 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000003723 186.0
CSH2_k127_4775473_11 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.000000000000000000000000000000000000000003759 178.0
CSH2_k127_4775473_12 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.000000000000000000000000000000000000000003959 163.0
CSH2_k127_4775473_13 - - - - 0.0000000966 61.0
CSH2_k127_4775473_14 Rubrerythrin - - - 0.0005907 48.0
CSH2_k127_4775473_2 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 422.0
CSH2_k127_4775473_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 344.0
CSH2_k127_4775473_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 338.0
CSH2_k127_4775473_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 324.0
CSH2_k127_4775473_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000139 282.0
CSH2_k127_4775473_7 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008076 282.0
CSH2_k127_4775473_8 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001974 251.0
CSH2_k127_4775473_9 isomerase activity K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000001242 238.0
CSH2_k127_4816358_0 Heat shock 70 kDa protein K04043 - - 2.966e-263 824.0
CSH2_k127_4816358_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 7.917e-232 729.0
CSH2_k127_4816358_10 protein conserved in archaea - - - 0.000000000000001026 85.0
CSH2_k127_4816358_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000000000396 81.0
CSH2_k127_4816358_12 - - - - 0.000000001022 61.0
CSH2_k127_4816358_13 Histidine biosynthesis protein K01814 - 5.3.1.16 0.00002658 55.0
CSH2_k127_4816358_2 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 531.0
CSH2_k127_4816358_3 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 398.0
CSH2_k127_4816358_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000005112 177.0
CSH2_k127_4816358_5 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000000000000000000001134 135.0
CSH2_k127_4816358_6 LemA family K03744 - - 0.00000000000000000000000000000007464 132.0
CSH2_k127_4816358_7 ERCC4 domain K10896 - - 0.000000000000000000000000000003697 131.0
CSH2_k127_4816358_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000000000000001094 119.0
CSH2_k127_4816358_9 Methanol dehydrogenase K06872 - - 0.0000000000000000000000001681 115.0
CSH2_k127_4845280_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1160.0
CSH2_k127_4845280_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 7.878e-248 780.0
CSH2_k127_4845280_10 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K02192,K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0022900,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0072592,GO:0097159,GO:1901265,GO:1901363 1.6.3.4,1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 299.0
CSH2_k127_4845280_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 296.0
CSH2_k127_4845280_12 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 297.0
CSH2_k127_4845280_13 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001894 283.0
CSH2_k127_4845280_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001691 272.0
CSH2_k127_4845280_15 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002119 265.0
CSH2_k127_4845280_16 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002975 268.0
CSH2_k127_4845280_17 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000006728 241.0
CSH2_k127_4845280_18 nitrogen compound transport K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000000000000000001032 243.0
CSH2_k127_4845280_19 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000004089 242.0
CSH2_k127_4845280_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.248e-243 781.0
CSH2_k127_4845280_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000006303 226.0
CSH2_k127_4845280_21 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001166 219.0
CSH2_k127_4845280_22 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000001489 228.0
CSH2_k127_4845280_23 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000008916 202.0
CSH2_k127_4845280_24 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000003517 170.0
CSH2_k127_4845280_25 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000001643 183.0
CSH2_k127_4845280_26 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000376 160.0
CSH2_k127_4845280_27 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.000000000000000000000000000000000000000009356 167.0
CSH2_k127_4845280_28 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000002814 144.0
CSH2_k127_4845280_29 - - - - 0.00000000000000000000000000000000000006728 148.0
CSH2_k127_4845280_3 O-acetylhomoserine K01740 - 2.5.1.49 3.794e-199 628.0
CSH2_k127_4845280_30 Flavodoxin - - - 0.000000000000000000000000000000000006431 143.0
CSH2_k127_4845280_31 VIT family - - - 0.00000000000000000000000000000000009846 140.0
CSH2_k127_4845280_32 - - - - 0.000000000000000000000000000000002376 134.0
CSH2_k127_4845280_33 - - - - 0.0000000000000000000000000000001333 132.0
CSH2_k127_4845280_34 Transcriptional regulator K07722 - - 0.0000000000000000000000000001825 120.0
CSH2_k127_4845280_35 Transcriptional regulator - - - 0.000000000000004525 83.0
CSH2_k127_4845280_36 PQ loop repeat K15383 - - 0.0000000000003052 73.0
CSH2_k127_4845280_37 cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000003404 76.0
CSH2_k127_4845280_38 PFAM Thioredoxin domain K03672 - 1.8.1.8 0.000000001403 64.0
CSH2_k127_4845280_39 Belongs to the WrbA family K03809 - 1.6.5.2 0.00002046 53.0
CSH2_k127_4845280_4 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 500.0
CSH2_k127_4845280_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 463.0
CSH2_k127_4845280_6 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 378.0
CSH2_k127_4845280_7 aminoglycoside K00662 - 2.3.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 310.0
CSH2_k127_4845280_8 PFAM Beta propeller domain K14475 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 321.0
CSH2_k127_4845280_9 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 291.0
CSH2_k127_5098099_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000003784 224.0
CSH2_k127_5098099_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000142 127.0
CSH2_k127_5098099_2 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.000000000000005027 85.0
CSH2_k127_5098099_3 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.0000003157 54.0
CSH2_k127_5098099_4 exo-alpha-(2->6)-sialidase activity - - - 0.000005739 60.0
CSH2_k127_5111440_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 2.538e-235 745.0
CSH2_k127_5111440_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 526.0
CSH2_k127_5111440_10 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000057 59.0
CSH2_k127_5111440_11 Membrane K03893 - - 0.00002533 48.0
CSH2_k127_5111440_2 C-terminal region of MMR_HSR1 domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 411.0
CSH2_k127_5111440_3 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 321.0
CSH2_k127_5111440_4 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000507 254.0
CSH2_k127_5111440_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006021 244.0
CSH2_k127_5111440_6 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000002442 243.0
CSH2_k127_5111440_7 archaeal coiled-coil protein - - - 0.0000000000000000000000000000436 132.0
CSH2_k127_5111440_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000001347 107.0
CSH2_k127_5111440_9 - - - - 0.0000000000000000876 83.0
CSH2_k127_5180586_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 308.0
CSH2_k127_5180586_1 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000001777 235.0
CSH2_k127_5227195_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.331e-199 637.0
CSH2_k127_5227195_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 466.0
CSH2_k127_5227195_10 Iron-sulphur cluster biosynthesis K15724 - - 0.0000000000000000008793 91.0
CSH2_k127_5227195_11 Helix-turn-helix XRE-family like proteins K07108 - - 0.0000000000000003712 83.0
CSH2_k127_5227195_12 - - - - 0.000004083 57.0
CSH2_k127_5227195_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 445.0
CSH2_k127_5227195_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 401.0
CSH2_k127_5227195_4 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 386.0
CSH2_k127_5227195_5 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002207 283.0
CSH2_k127_5227195_6 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004844 274.0
CSH2_k127_5227195_7 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000001377 237.0
CSH2_k127_5227195_8 DEAD DEAH box helicase domain protein K10896 - - 0.0000000000000000000000000000000000000000000000000000001403 199.0
CSH2_k127_5227195_9 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000003021 130.0
CSH2_k127_5755812_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 587.0
CSH2_k127_5755812_1 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 308.0
CSH2_k127_5755812_10 PRC-barrel domain - - - 0.00000000000000001368 86.0
CSH2_k127_5755812_11 response to oxidative stress K04063 - - 0.00000000000000003451 88.0
CSH2_k127_5755812_12 Glutamine amidotransferases class-II - - - 0.00000000000008787 81.0
CSH2_k127_5755812_13 - - - - 0.0000000000006961 72.0
CSH2_k127_5755812_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000002908 192.0
CSH2_k127_5755812_3 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000005852 186.0
CSH2_k127_5755812_4 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000003148 175.0
CSH2_k127_5755812_5 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000000003913 168.0
CSH2_k127_5755812_6 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000000759 165.0
CSH2_k127_5755812_7 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000002616 163.0
CSH2_k127_5755812_8 NMT1-like family K02051 - - 0.0000000000000000000000000000000000001674 155.0
CSH2_k127_5755812_9 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000002195 139.0
CSH2_k127_5850357_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1037.0
CSH2_k127_5850357_1 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 2.399e-201 642.0
CSH2_k127_5850357_10 Membrane - - - 0.00000000000000000000000000000000000000001507 162.0
CSH2_k127_5850357_11 Universal stress protein family - - - 0.00000000000000000000000000000000002534 139.0
CSH2_k127_5850357_12 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000004753 132.0
CSH2_k127_5850357_13 Methyltransferase domain - - - 0.00000000000000000000000000004375 124.0
CSH2_k127_5850357_14 - - - - 0.0000000000000000000000521 104.0
CSH2_k127_5850357_15 Pfam:DUF59 - - - 0.000000000000000000007484 94.0
CSH2_k127_5850357_16 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000001362 89.0
CSH2_k127_5850357_17 Phosphoesterase PA-phosphatase - - - 0.0000000000000004044 90.0
CSH2_k127_5850357_18 Mo-molybdopterin cofactor metabolic process K00366,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.7.7.1,2.7.7.80,2.8.1.11 0.000000000007233 68.0
CSH2_k127_5850357_19 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 K03768 - 5.2.1.8 0.000000002435 68.0
CSH2_k127_5850357_2 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 434.0
CSH2_k127_5850357_3 ATPase P K17686 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 337.0
CSH2_k127_5850357_4 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 336.0
CSH2_k127_5850357_5 lactate oxidation K00782,K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 319.0
CSH2_k127_5850357_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005478 275.0
CSH2_k127_5850357_7 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009289 259.0
CSH2_k127_5850357_8 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001966 252.0
CSH2_k127_5850357_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000008244 240.0
CSH2_k127_5966834_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 608.0
CSH2_k127_5966834_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 521.0
CSH2_k127_5966834_10 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0002689 56.0
CSH2_k127_5966834_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 407.0
CSH2_k127_5966834_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000001106 175.0
CSH2_k127_5966834_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000004647 148.0
CSH2_k127_5966834_5 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000953 115.0
CSH2_k127_5966834_6 dihydromethanopterin reductase activity - - - 0.00000000000000000001187 103.0
CSH2_k127_5966834_7 transporter permease K02033 - - 0.0000000000008517 79.0
CSH2_k127_5966834_8 COG1520 FOG WD40-like repeat K17713 - - 0.0000000001723 77.0
CSH2_k127_5966834_9 Acetyltransferase (GNAT) domain - - - 0.000004351 57.0
CSH2_k127_6009289_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 415.0
CSH2_k127_6009289_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000855 246.0
CSH2_k127_6009289_2 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000104 211.0
CSH2_k127_6009289_3 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000002002 133.0
CSH2_k127_6009289_4 - - - - 0.000000000000000000000000001245 124.0
CSH2_k127_6009289_5 Protein of unknown function DUF131 - - - 0.00000000005103 68.0
CSH2_k127_6009289_6 PAC2 family K06869 - - 0.000000387 56.0
CSH2_k127_6068777_0 4Fe-4S single cluster domain K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 573.0
CSH2_k127_6068777_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 574.0
CSH2_k127_6068777_10 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000002398 266.0
CSH2_k127_6068777_11 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005531 267.0
CSH2_k127_6068777_12 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000472 252.0
CSH2_k127_6068777_13 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000004645 231.0
CSH2_k127_6068777_14 Archaeal transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000000000001242 223.0
CSH2_k127_6068777_15 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.000000000000000000000000000000000000000000000000000003819 195.0
CSH2_k127_6068777_16 PFAM glycosyl transferase group 1 K13677 - 2.4.1.208 0.00000000000000000000000000000000000000000000000000004106 201.0
CSH2_k127_6068777_17 Lamin Tail Domain - - - 0.00000000000000000000000000000000000000000000000001003 209.0
CSH2_k127_6068777_18 methanogen marker protein 4 - - - 0.00000000000000000000000000000000000000000000005513 179.0
CSH2_k127_6068777_19 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000001173 177.0
CSH2_k127_6068777_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 497.0
CSH2_k127_6068777_20 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000007748 153.0
CSH2_k127_6068777_21 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000001477 140.0
CSH2_k127_6068777_23 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840 - 0.00000000000000000000000000000004645 128.0
CSH2_k127_6068777_24 PFAM polysaccharide biosynthesis protein - - - 0.000000000000000000000000000005223 136.0
CSH2_k127_6068777_25 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000000000001279 123.0
CSH2_k127_6068777_26 - - - - 0.0000000000000000000001508 104.0
CSH2_k127_6068777_27 Serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000001995 94.0
CSH2_k127_6068777_28 - K00390 - 1.8.4.10,1.8.4.8 0.0000000000000009257 81.0
CSH2_k127_6068777_29 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.000000000000001691 80.0
CSH2_k127_6068777_3 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 422.0
CSH2_k127_6068777_30 ACT domain protein - - - 0.000000000000007875 79.0
CSH2_k127_6068777_31 RNA-binding protein containing KH domain possibly ribosomal protein K07574 GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - 0.0000000001766 65.0
CSH2_k127_6068777_32 PKD domain - - - 0.000000003503 63.0
CSH2_k127_6068777_33 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000001215 57.0
CSH2_k127_6068777_34 4-amino-4-deoxy-L-arabinose transferase activity K00728 - 2.4.1.109 0.000004002 59.0
CSH2_k127_6068777_35 Psort location Cytoplasmic, score - - - 0.00002215 55.0
CSH2_k127_6068777_4 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 402.0
CSH2_k127_6068777_6 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 294.0
CSH2_k127_6068777_7 GtrA-like protein K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000177 292.0
CSH2_k127_6068777_8 glutathione-regulated potassium exporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004422 291.0
CSH2_k127_6068777_9 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000001895 270.0
CSH2_k127_6110513_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 325.0
CSH2_k127_6110513_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008187 267.0
CSH2_k127_6110513_2 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000000000000000000000000000000000001779 202.0
CSH2_k127_6110513_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.000000000000000000000000000000000000000000000000000003365 197.0
CSH2_k127_6110513_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000001579 195.0
CSH2_k127_6110513_5 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000000000000003982 163.0
CSH2_k127_6110513_6 Radical SAM - - - 0.000000000000000000000000001151 115.0
CSH2_k127_6110513_7 Ribbon-helix-helix protein, copG family K07722 - - 0.0000000000000000000009614 98.0
CSH2_k127_6123022_0 Type II/IV secretion system protein K07332 - - 1.77e-223 707.0
CSH2_k127_6123022_1 Type II/IV secretion system protein K07332 - - 3.042e-216 686.0
CSH2_k127_6123022_10 - - - - 0.000000000000000009738 89.0
CSH2_k127_6123022_11 PFAM PKD domain containing protein - - - 0.00000000000008884 83.0
CSH2_k127_6123022_2 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008666 628.0
CSH2_k127_6123022_3 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009851 405.0
CSH2_k127_6123022_4 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 395.0
CSH2_k127_6123022_5 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001327 286.0
CSH2_k127_6123022_6 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000002987 237.0
CSH2_k127_6123022_7 Protein of unknown function (DUF531) K09725 - - 0.00000000000000000000000000000000000000000000000000001651 194.0
CSH2_k127_6123022_8 Oxidoreductase K10678,K19286 - 1.5.1.39 0.0000000000000000000001124 108.0
CSH2_k127_6123022_9 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000001319 87.0
CSH2_k127_6132476_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 599.0
CSH2_k127_6132476_1 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 337.0
CSH2_k127_6132476_2 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000619 263.0
CSH2_k127_6132476_3 Dehydrogenase K00005 - 1.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000004508 262.0
CSH2_k127_6132476_4 Protein of unknown function TPD sequence-motif - - - 0.00000000000000000000000000000000000000000000000000000000006225 213.0
CSH2_k127_6132476_5 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000000000000000000000000000000000000000795 209.0
CSH2_k127_6132476_6 Cysteine-rich domain - - - 0.0000000000000000008594 89.0
CSH2_k127_6309496_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.429e-271 848.0
CSH2_k127_6309496_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.235e-210 668.0
CSH2_k127_6309496_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 491.0
CSH2_k127_6309496_3 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000001309 232.0
CSH2_k127_6309496_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000001348 219.0
CSH2_k127_6309496_5 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000002804 198.0
CSH2_k127_6309496_6 Double zinc ribbon - - - 0.0000008416 62.0
CSH2_k127_6309496_7 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000008247 51.0
CSH2_k127_6371109_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 569.0
CSH2_k127_6371109_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 580.0
CSH2_k127_6371109_10 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 312.0
CSH2_k127_6371109_11 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 312.0
CSH2_k127_6371109_12 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 327.0
CSH2_k127_6371109_13 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004701 284.0
CSH2_k127_6371109_14 Kef-type K transport K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002417 289.0
CSH2_k127_6371109_15 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000001546 271.0
CSH2_k127_6371109_16 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000875 274.0
CSH2_k127_6371109_17 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006 280.0
CSH2_k127_6371109_18 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005502 251.0
CSH2_k127_6371109_19 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000781 246.0
CSH2_k127_6371109_2 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 467.0
CSH2_k127_6371109_20 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000004656 201.0
CSH2_k127_6371109_21 shikimate kinase activity K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000001999 187.0
CSH2_k127_6371109_22 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000001429 186.0
CSH2_k127_6371109_23 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000007923 180.0
CSH2_k127_6371109_24 Belongs to the UPF0280 family K09740 - - 0.000000000000000000000000000000000000000000001596 176.0
CSH2_k127_6371109_25 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.00000000000000000000000000000000000000000001525 165.0
CSH2_k127_6371109_26 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000004347 171.0
CSH2_k127_6371109_27 Archaeal Type IV pilin, N-terminal - - - 0.000000000000000000000000000000000000000001325 183.0
CSH2_k127_6371109_28 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000001731 152.0
CSH2_k127_6371109_29 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000000000000000000000000000000000002256 151.0
CSH2_k127_6371109_3 COG0531 Amino acid transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 420.0
CSH2_k127_6371109_30 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000000000000000000000000000008347 146.0
CSH2_k127_6371109_31 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000000000000000000816 140.0
CSH2_k127_6371109_32 PFAM NIL domain - - - 0.0000000000000000000000000000001359 127.0
CSH2_k127_6371109_33 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.000000000000000000000000000001943 130.0
CSH2_k127_6371109_34 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000026 126.0
CSH2_k127_6371109_35 COG3291 FOG PKD repeat - - - 0.00000000000000000000000000003827 139.0
CSH2_k127_6371109_36 Peptidase family M28 - - - 0.00000000000000000000000000004496 130.0
CSH2_k127_6371109_37 nucleotide metabolic process - - - 0.0000000000000000000000004249 114.0
CSH2_k127_6371109_38 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000001285 124.0
CSH2_k127_6371109_39 - - - - 0.000000000000000000001166 108.0
CSH2_k127_6371109_4 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 402.0
CSH2_k127_6371109_40 FlgD Ig-like domain K15924 - 3.2.1.136 0.000000000000000000005638 109.0
CSH2_k127_6371109_41 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000005925 94.0
CSH2_k127_6371109_42 PFAM PKD domain containing protein - - - 0.0000000000000009812 91.0
CSH2_k127_6371109_43 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000002068 82.0
CSH2_k127_6371109_44 OmpA family - - - 0.000000000001722 82.0
CSH2_k127_6371109_45 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000001403 76.0
CSH2_k127_6371109_46 Zinc metalloprotease (Elastase) K01183 - 3.2.1.14 0.00000001534 70.0
CSH2_k127_6371109_5 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 382.0
CSH2_k127_6371109_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 372.0
CSH2_k127_6371109_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 350.0
CSH2_k127_6371109_8 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 323.0
CSH2_k127_6371109_9 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 323.0
CSH2_k127_6383390_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000002408 147.0
CSH2_k127_6383390_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000008487 59.0
CSH2_k127_6710156_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000000000000404 223.0
CSH2_k127_6710156_1 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000001504 205.0
CSH2_k127_6710156_2 Phenazine biosynthesis protein phzf family - - - 0.00000000000000000000000000000000000000000000000000009142 197.0
CSH2_k127_6710156_3 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.000000000000000000336 91.0
CSH2_k127_6710156_4 Bacterial periplasmic substrate-binding proteins - - - 0.00002835 52.0
CSH2_k127_7202_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 326.0
CSH2_k127_7202_1 alkyl hydroperoxide reductase activity - - - 0.0000000000000000000000000001502 120.0
CSH2_k127_7202_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000338 95.0
CSH2_k127_867277_0 lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 542.0
CSH2_k127_867277_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 327.0
CSH2_k127_867277_10 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000002254 211.0
CSH2_k127_867277_11 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000003985 200.0
CSH2_k127_867277_12 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000000002208 198.0
CSH2_k127_867277_13 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000009668 192.0
CSH2_k127_867277_14 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.0000000000000000000000000000000000000000002993 166.0
CSH2_k127_867277_15 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000001701 162.0
CSH2_k127_867277_16 Transcriptional regulator, ArsR family - - - 0.000000000000000000000000000000000000001498 153.0
CSH2_k127_867277_17 hydrolase (HAD superfamily) K07025 - - 0.000000000000000000000000000000000000006599 156.0
CSH2_k127_867277_18 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000003598 136.0
CSH2_k127_867277_19 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000002139 143.0
CSH2_k127_867277_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 288.0
CSH2_k127_867277_20 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000003234 126.0
CSH2_k127_867277_21 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000000000004441 119.0
CSH2_k127_867277_23 - K06039,K07092 - - 0.000000000000000000000001984 107.0
CSH2_k127_867277_24 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000003534 103.0
CSH2_k127_867277_25 PKD domain - - - 0.0000000000000000000003773 114.0
CSH2_k127_867277_26 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001568 89.0
CSH2_k127_867277_27 PFAM Peptidase C11, clostripain - - - 0.0000000000000002697 95.0
CSH2_k127_867277_28 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000000004601 78.0
CSH2_k127_867277_29 OmpA family K02557,K03286 - - 0.000000002999 72.0
CSH2_k127_867277_3 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 287.0
CSH2_k127_867277_30 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00001726 51.0
CSH2_k127_867277_31 Antifreeze protein type I - - - 0.0008956 50.0
CSH2_k127_867277_4 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001321 276.0
CSH2_k127_867277_5 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007004 262.0
CSH2_k127_867277_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000002219 259.0
CSH2_k127_867277_7 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000001834 245.0
CSH2_k127_867277_8 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016772,GO:0016776,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0102043,GO:1901576 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000003197 214.0
CSH2_k127_867277_9 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000008451 211.0
CSH2_k127_894238_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 5.05e-246 773.0
CSH2_k127_894238_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 4.022e-218 718.0
CSH2_k127_894238_10 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000001737 211.0
CSH2_k127_894238_11 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000001205 199.0
CSH2_k127_894238_12 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000002592 192.0
CSH2_k127_894238_13 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000000000000000000000001735 183.0
CSH2_k127_894238_14 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000181 185.0
CSH2_k127_894238_15 AAA domain - - - 0.000000000000000000000000000000000000000000000045 175.0
CSH2_k127_894238_16 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000003925 161.0
CSH2_k127_894238_17 DsrE/DsrF-like family K07235 - - 0.00000000000000000000000000000000000465 139.0
CSH2_k127_894238_18 Sodium Bile acid symporter family K03453 - - 0.000000000000000000000000000000004896 139.0
CSH2_k127_894238_19 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000000007842 113.0
CSH2_k127_894238_2 oligoendopeptidase F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006436 414.0
CSH2_k127_894238_20 redox protein regulator of disulfide bond formation - - - 0.00000000000000000000000002602 111.0
CSH2_k127_894238_21 ABC-2 family transporter protein K01992 - - 0.000000000000000000000003495 116.0
CSH2_k127_894238_22 Response regulator receiver domain - - - 0.000000000000000000009444 97.0
CSH2_k127_894238_23 4Fe-4S dicluster domain - - - 0.0000000000000000004134 90.0
CSH2_k127_894238_24 protein involved in the oxidation of intracellular sulfur K07236 - - 0.00000000000002189 78.0
CSH2_k127_894238_25 Roadblock/LC7 domain K07131 - - 0.000000003583 63.0
CSH2_k127_894238_26 - K21029 - 2.7.7.80 0.00001494 50.0
CSH2_k127_894238_27 PFAM Peptidase C11, clostripain - - - 0.00001587 56.0
CSH2_k127_894238_28 sulfur relay protein TusB DsrH K07237 - - 0.000146 48.0
CSH2_k127_894238_3 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 396.0
CSH2_k127_894238_4 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 323.0
CSH2_k127_894238_5 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 303.0
CSH2_k127_894238_6 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004425 298.0
CSH2_k127_894238_7 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002095 276.0
CSH2_k127_894238_8 ATPases associated with a variety of cellular activities K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003483 248.0
CSH2_k127_894238_9 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000002741 229.0
CSH2_k127_903995_0 Dehydratase family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000867 614.0
CSH2_k127_903995_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 531.0
CSH2_k127_903995_10 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000006778 247.0
CSH2_k127_903995_11 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000008476 237.0
CSH2_k127_903995_12 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000007265 204.0
CSH2_k127_903995_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000003076 188.0
CSH2_k127_903995_14 transcription regulator activity - - - 0.00000000000000000000000000000000000000000004495 164.0
CSH2_k127_903995_15 Protein of unknown function (DUF835) - - - 0.00000000000006252 84.0
CSH2_k127_903995_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 523.0
CSH2_k127_903995_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 460.0
CSH2_k127_903995_4 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 414.0
CSH2_k127_903995_5 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 412.0
CSH2_k127_903995_6 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 349.0
CSH2_k127_903995_7 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005892 284.0
CSH2_k127_903995_8 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001739 262.0
CSH2_k127_903995_9 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006789 267.0
CSH2_k127_936181_0 Proton-conducting membrane transporter K05565,K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 595.0
CSH2_k127_936181_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 496.0
CSH2_k127_936181_10 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 305.0
CSH2_k127_936181_11 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 294.0
CSH2_k127_936181_12 ABC-type dipeptide oligopeptide nickel transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006082 282.0
CSH2_k127_936181_13 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002033 272.0
CSH2_k127_936181_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001667 271.0
CSH2_k127_936181_15 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000001091 254.0
CSH2_k127_936181_16 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000007286 243.0
CSH2_k127_936181_17 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000001526 226.0
CSH2_k127_936181_18 Family 5 K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000237 229.0
CSH2_k127_936181_19 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000004195 214.0
CSH2_k127_936181_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 398.0
CSH2_k127_936181_20 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000000000000000000000000000000000006074 206.0
CSH2_k127_936181_21 Belongs to the FPP GGPP synthase family K00805,K21275 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 0.000000000000000000000000000000000000000000000000000000001476 213.0
CSH2_k127_936181_22 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.000000000000000000000000000000000000000000000003118 179.0
CSH2_k127_936181_23 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000003016 170.0
CSH2_k127_936181_24 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.0000000000000000000000000000000000000000000003309 182.0
CSH2_k127_936181_25 4Fe-4S dicluster domain K00338,K14121,K22164,K22176 - 1.1.98.4,1.5.98.3,1.6.5.3 0.0000000000000000000000000000000008415 144.0
CSH2_k127_936181_26 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000781 134.0
CSH2_k127_936181_27 PIN domain of ribonuclease K07060 - - 0.00000000000000000000000000000002607 131.0
CSH2_k127_936181_28 metal-dependent phosphoesterases (PHP family) - - - 0.00000000000000000000000000005172 124.0
CSH2_k127_936181_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000009044 123.0
CSH2_k127_936181_3 Belongs to the complex I 49 kDa subunit family K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 397.0
CSH2_k127_936181_30 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000005187 121.0
CSH2_k127_936181_31 NADH ubiquinone oxidoreductase subunit 11 or 4L (Chain K) K00340 - 1.6.5.3 0.0000000000000000000000001346 111.0
CSH2_k127_936181_32 NADH ubiquinone oxidoreductase subunit 3 (Chain a) K00330,K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3,1.6.5.3 0.00000000000000000000000244 107.0
CSH2_k127_936181_33 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000004398 93.0
CSH2_k127_936181_34 NADH ubiquinone oxidoreductase subunit 6 (chain J) K00339 - 1.6.5.3 0.000000001003 63.0
CSH2_k127_936181_4 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K00343,K22169 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 397.0
CSH2_k127_936181_5 Proton-conducting membrane transporter K22168 - 1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 387.0
CSH2_k127_936181_6 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 362.0
CSH2_k127_936181_7 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 352.0
CSH2_k127_936181_8 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 350.0
CSH2_k127_936181_9 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 324.0
CSH2_k127_960581_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1107.0
CSH2_k127_960581_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 596.0
CSH2_k127_960581_10 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.000000000000000000000000000000000000000000000000000000000004311 217.0
CSH2_k127_960581_11 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000002088 212.0
CSH2_k127_960581_12 - - - - 0.0000000000000000000000000000000000005025 150.0
CSH2_k127_960581_13 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000275 122.0
CSH2_k127_960581_14 spore germination K03605 - - 0.0000000000000000000000000002973 121.0
CSH2_k127_960581_15 - - - - 0.0000000000000000000187 101.0
CSH2_k127_960581_16 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000179 90.0
CSH2_k127_960581_17 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000001139 62.0
CSH2_k127_960581_2 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 499.0
CSH2_k127_960581_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 461.0
CSH2_k127_960581_4 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 414.0
CSH2_k127_960581_5 NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K17994,K18007 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 352.0
CSH2_k127_960581_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004397 245.0
CSH2_k127_960581_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000198 242.0
CSH2_k127_960581_8 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000002466 231.0
CSH2_k127_960581_9 Acetamidase formamidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000002824 238.0
CSH2_k127_962887_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 2.072e-223 706.0
CSH2_k127_962887_1 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 9.417e-216 685.0
CSH2_k127_962887_10 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 241.0
CSH2_k127_962887_11 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.00000000000000000000000000000000000000000000000000000000000000001577 235.0
CSH2_k127_962887_12 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000004136 216.0
CSH2_k127_962887_13 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000001102 194.0
CSH2_k127_962887_14 helix_turn_helix ASNC type K03718 - - 0.00000000000000000000000000000000000000000007278 165.0
CSH2_k127_962887_15 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000009314 130.0
CSH2_k127_962887_16 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000004696 117.0
CSH2_k127_962887_17 molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.000000000000000000000002876 111.0
CSH2_k127_962887_18 Protein of unknown function (DUF2797) - - - 0.000002083 59.0
CSH2_k127_962887_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 407.0
CSH2_k127_962887_3 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 385.0
CSH2_k127_962887_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 373.0
CSH2_k127_962887_5 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 355.0
CSH2_k127_962887_6 methanogenesis marker protein 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 355.0
CSH2_k127_962887_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007875 278.0
CSH2_k127_962887_8 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000802 274.0
CSH2_k127_962887_9 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003507 259.0