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Overview

ID MAG00608
Name CSH2_bin.20
Sample SMP0014
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family Dissulfurispiraceae
Genus
Species
Assembly information
Completeness (%) 67.31
Contamination (%) 1.8
GC content (%) 58.0
N50 (bp) 2,856
Genome size (bp) 1,462,388

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1567

Gene name Description KEGG GOs EC E-value Score Sequence
CSH2_k127_1004880_0 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000000000000000000000000000000000000000000000002381 256.0
CSH2_k127_1004880_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000004738 176.0
CSH2_k127_1011286_0 Glycosyl hydrolases family 15 - - - 7.607e-248 783.0
CSH2_k127_1011286_1 Protein of unknown function (DUF2769) - - - 0.000002467 50.0
CSH2_k127_1011286_2 Glucose / Sorbosone dehydrogenase - - - 0.0001065 50.0
CSH2_k127_1011286_3 Cytochrome c K08738 - - 0.0001986 52.0
CSH2_k127_1016341_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 443.0
CSH2_k127_1016341_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000004922 208.0
CSH2_k127_1024015_0 lyase activity K01932 - - 0.00000000000000000000000000001883 122.0
CSH2_k127_1024015_1 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000001973 104.0
CSH2_k127_1034290_0 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 286.0
CSH2_k127_1034290_1 IMP dehydrogenase activity - - - 0.00000000000000000000000000000001775 130.0
CSH2_k127_1034290_2 IMP dehydrogenase activity - - - 0.000000000000000000000000001357 117.0
CSH2_k127_1057806_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000001045 195.0
CSH2_k127_1058277_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 428.0
CSH2_k127_1058277_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000009346 246.0
CSH2_k127_108277_0 PFAM metal-dependent phosphohydrolase HD sub - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 313.0
CSH2_k127_108277_1 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001469 254.0
CSH2_k127_108277_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000002657 52.0
CSH2_k127_1118330_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 363.0
CSH2_k127_1118330_1 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 343.0
CSH2_k127_1119356_0 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000531 229.0
CSH2_k127_1119356_1 PFAM Tetratricopeptide repeat - - - 0.00001962 50.0
CSH2_k127_1123126_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 334.0
CSH2_k127_1123126_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 316.0
CSH2_k127_1123126_2 Protein of unknown function (DUF433) - - - 0.0000000000000313 77.0
CSH2_k127_1123126_3 Binding-protein-dependent transport system inner membrane component K02031,K02034 - - 0.0000000000122 66.0
CSH2_k127_1129929_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000001156 231.0
CSH2_k127_1129929_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000001777 74.0
CSH2_k127_115924_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 406.0
CSH2_k127_115924_1 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 297.0
CSH2_k127_1160169_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 289.0
CSH2_k127_1160169_1 Outer membrane efflux protein - - - 0.000000000000000004328 91.0
CSH2_k127_1168957_0 AMP binding - - - 0.00000000000000000000000000000000000000000001123 173.0
CSH2_k127_1168957_1 Thiamine-binding protein - - - 0.000000000000000000000000000001192 123.0
CSH2_k127_1168957_2 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000002164 118.0
CSH2_k127_117287_0 3-beta hydroxysteroid dehydrogenase/isomerase family K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000001802 228.0
CSH2_k127_117287_1 C-methyltransferase C-terminal domain - - - 0.00000000000000000006228 100.0
CSH2_k127_1225914_0 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000004079 200.0
CSH2_k127_1225914_1 general secretion pathway protein K02456,K02457,K02458,K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000001096 61.0
CSH2_k127_1225914_2 Prokaryotic N-terminal methylation motif K02457 - - 0.000001418 56.0
CSH2_k127_1225914_3 Protein of unknown function (DUF1016) - - - 0.00002703 46.0
CSH2_k127_1246549_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 561.0
CSH2_k127_1246549_1 PFAM glycosyl transferase, family 9 K02849 - - 0.000000000000000000000001019 112.0
CSH2_k127_1246549_2 Aminotransferase class-III K01845 - 5.4.3.8 0.000000001476 61.0
CSH2_k127_1281217_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 4.038e-268 854.0
CSH2_k127_1281217_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000002152 145.0
CSH2_k127_1295044_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 323.0
CSH2_k127_1295044_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03408 - - 0.00000002394 56.0
CSH2_k127_1300730_0 pilus assembly protein PilW K02459,K02672 - - 0.000000001744 68.0
CSH2_k127_1300730_1 type IV pilus modification protein PilV K02458,K02671 - - 0.000007085 55.0
CSH2_k127_1326420_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.895e-199 629.0
CSH2_k127_1326420_1 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000000003177 183.0
CSH2_k127_1326420_2 cell redox homeostasis K02199 - - 0.000000000000000000000000000000002416 135.0
CSH2_k127_1341035_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 512.0
CSH2_k127_1341035_1 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 430.0
CSH2_k127_1341035_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 353.0
CSH2_k127_1345698_0 ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 372.0
CSH2_k127_1360974_0 4Fe-4S binding domain K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 327.0
CSH2_k127_1360974_1 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000000000000000000000000000002009 161.0
CSH2_k127_1360974_2 TIGRFAM MauM NapG family ferredoxin-type protein K02573 - - 0.00000000000000004671 82.0
CSH2_k127_1360974_3 negative regulation of establishment of protein localization K02570 GO:0003674,GO:0005048,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032879,GO:0032880,GO:0033218,GO:0042277,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0051049,GO:0051051,GO:0051223,GO:0051224,GO:0065007,GO:0070201,GO:0090087,GO:1904950 - 0.0000000000002922 72.0
CSH2_k127_1361318_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 402.0
CSH2_k127_1361318_1 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004083 258.0
CSH2_k127_1361318_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000002023 65.0
CSH2_k127_1361318_3 Glycosyl transferase family 2 - - - 0.0000002593 59.0
CSH2_k127_1376504_0 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 340.0
CSH2_k127_1376504_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007952 275.0
CSH2_k127_1376504_2 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000003163 192.0
CSH2_k127_1376504_3 protein methyltransferase activity K00595 - 2.1.1.132 0.00000001633 57.0
CSH2_k127_1384613_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 301.0
CSH2_k127_1384613_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000003512 241.0
CSH2_k127_1384613_2 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000003294 235.0
CSH2_k127_1386580_0 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002953 274.0
CSH2_k127_1428668_0 Sigma-54 interaction domain - - - 2.293e-209 659.0
CSH2_k127_1428668_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 395.0
CSH2_k127_1428668_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000002068 104.0
CSH2_k127_1433626_0 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000000000001789 188.0
CSH2_k127_1433626_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000001582 159.0
CSH2_k127_1433626_2 Glycosyltransferase like family 2 K20444 - - 0.0000006805 52.0
CSH2_k127_1438777_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 586.0
CSH2_k127_1438777_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 346.0
CSH2_k127_1449765_0 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 422.0
CSH2_k127_1449765_1 Universal stress protein family - - - 0.000000000000000000003545 99.0
CSH2_k127_1449765_2 - - - - 0.00005303 47.0
CSH2_k127_1449765_3 - - - - 0.00007672 54.0
CSH2_k127_1460516_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 1.209e-228 733.0
CSH2_k127_1460516_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 448.0
CSH2_k127_1460516_2 TIGRFAM molybdenum cofactor synthesis domain - - - 0.000000000000000000000000000000000000000000000000000000000000001557 221.0
CSH2_k127_1460516_3 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000112 210.0
CSH2_k127_1474782_0 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 526.0
CSH2_k127_1474782_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000004217 166.0
CSH2_k127_1474810_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 552.0
CSH2_k127_1474810_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588,K01945 - 5.4.99.18,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000001046 251.0
CSH2_k127_1488864_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 346.0
CSH2_k127_1488864_1 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003221 259.0
CSH2_k127_1488864_2 PilZ domain - - - 0.0005155 46.0
CSH2_k127_1489225_0 PFAM molybdopterin oxidoreductase K00123,K05299 - 1.17.1.10,1.17.1.9 3.682e-214 677.0
CSH2_k127_1489225_1 2Fe-2S iron-sulfur cluster binding domain K05299 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 452.0
CSH2_k127_1489225_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K15022 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000005058 230.0
CSH2_k127_1489225_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000004219 212.0
CSH2_k127_150408_0 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 380.0
CSH2_k127_150408_1 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 370.0
CSH2_k127_150408_2 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000001319 172.0
CSH2_k127_150408_3 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000003375 117.0
CSH2_k127_1506605_0 HDOD domain - - - 0.0000000000000000000000000000000000000000000000001477 186.0
CSH2_k127_1506605_1 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000008503 192.0
CSH2_k127_1506605_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000005573 94.0
CSH2_k127_1506605_3 CHASE2 - - - 0.0006148 46.0
CSH2_k127_1532251_0 CoA binding domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 498.0
CSH2_k127_1532251_1 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 458.0
CSH2_k127_1532251_2 heme-binding sites - - - 0.000000000000000000000000000000000000000000000000000000000002811 221.0
CSH2_k127_1532251_3 PFAM ATP-grasp domain - - - 0.00000000000000000000000000000000000001571 149.0
CSH2_k127_1541292_0 CO dehydrogenase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 301.0
CSH2_k127_1541292_1 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000007599 94.0
CSH2_k127_154283_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 339.0
CSH2_k127_154283_1 Cupin - - - 0.0000000000000000000000000000000000000000000000000003072 188.0
CSH2_k127_154283_2 ABC-2 type transporter K01992,K09694 - - 0.00000000000000000000000004247 108.0
CSH2_k127_1546230_0 UDP-N-acetylmuramyl pentapeptide K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 278.0
CSH2_k127_1546230_1 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.000000000003836 68.0
CSH2_k127_1547754_0 Large extracellular alpha-helical protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 344.0
CSH2_k127_1553064_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000006667 224.0
CSH2_k127_1553064_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K03294 - - 0.0000001379 59.0
CSH2_k127_1556379_0 GAF domain - - - 1.078e-230 744.0
CSH2_k127_1556379_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000002601 222.0
CSH2_k127_1556379_2 phosphorelay signal transduction system - - - 0.0000000000000005546 86.0
CSH2_k127_1569608_0 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003405 250.0
CSH2_k127_1569608_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000001598 69.0
CSH2_k127_1578919_0 Flavodoxin - - - 8.279e-201 633.0
CSH2_k127_1578919_1 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000002018 239.0
CSH2_k127_1578919_2 Psort location Cytoplasmic, score - - - 0.000000002187 64.0
CSH2_k127_1578919_3 superoxide reductase activity K05919 - 1.15.1.2 0.00000005923 55.0
CSH2_k127_1586061_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.531e-288 902.0
CSH2_k127_1586061_1 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 381.0
CSH2_k127_1617245_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1347.0
CSH2_k127_1617245_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000001712 53.0
CSH2_k127_1617245_2 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.0000122 48.0
CSH2_k127_1642990_0 Tetrapyrrole (Corrin/Porphyrin) Methylases K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000017 276.0
CSH2_k127_1642990_1 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000000000000000000002601 156.0
CSH2_k127_1644544_0 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 344.0
CSH2_k127_1649197_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 337.0
CSH2_k127_1649197_1 YbbR-like protein - - - 0.0000000000000000000000000000000000000000000001087 179.0
CSH2_k127_164966_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000001257 181.0
CSH2_k127_165323_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.512e-212 667.0
CSH2_k127_165323_1 TIGRFAM oligoendopeptidase, pepF M3 family K08602 - - 0.000000000000000000000000000000000000000000000000000000000001222 217.0
CSH2_k127_1658961_0 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 322.0
CSH2_k127_1658961_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000002255 181.0
CSH2_k127_1658961_2 nickel cation binding K04651,K19640 - - 0.00000000000000000000000001051 111.0
CSH2_k127_1658961_3 carbon dioxide binding K04653 - - 0.000000000000000000000009275 103.0
CSH2_k127_1659453_0 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 390.0
CSH2_k127_1659453_1 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.0000000000000000000000000000000000000000000000000000000000001186 220.0
CSH2_k127_1663129_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 454.0
CSH2_k127_1663129_1 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 343.0
CSH2_k127_1663129_2 NosL - - - 0.0000000000000000000000000000000000000000000000000000000003766 205.0
CSH2_k127_1663129_3 - - - - 0.000000000000000000000000002058 115.0
CSH2_k127_1681872_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 1.456e-301 949.0
CSH2_k127_1681872_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 5.148e-277 871.0
CSH2_k127_1681872_2 Transcriptional regulator, MerR family - - - 0.000000000000000000000000000000000006491 141.0
CSH2_k127_1682653_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 430.0
CSH2_k127_1682653_1 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 394.0
CSH2_k127_1682653_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 294.0
CSH2_k127_1682653_3 PFAM sigma-54 factor interaction domain-containing protein K06714 - - 0.000000000000000000000000000000000000001758 153.0
CSH2_k127_1682653_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000004846 151.0
CSH2_k127_1682653_5 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000003554 124.0
CSH2_k127_1683475_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 439.0
CSH2_k127_1683475_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 286.0
CSH2_k127_1683475_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000006323 236.0
CSH2_k127_1683475_3 Evidence 5 No homology to any previously reported sequences K03765 - - 0.00000000000006913 83.0
CSH2_k127_1683475_4 Peptidase family M50 K11749 - - 0.00000000004067 64.0
CSH2_k127_1698195_0 alpha-L-arabinofuranosidase - - - 0.0005826 50.0
CSH2_k127_1717083_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 602.0
CSH2_k127_1717083_1 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001568 254.0
CSH2_k127_1717622_0 protein secretion K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009929 295.0
CSH2_k127_1717622_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000000000005211 129.0
CSH2_k127_1732023_0 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 499.0
CSH2_k127_1732023_1 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 310.0
CSH2_k127_1732023_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000001907 101.0
CSH2_k127_1750141_0 Fructose-bisphosphate aldolase class-II - - - 2.719e-203 644.0
CSH2_k127_1750141_1 Phosphofructokinase K00895,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000006263 141.0
CSH2_k127_1756161_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 458.0
CSH2_k127_1756161_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 287.0
CSH2_k127_1756161_2 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000000000000006433 211.0
CSH2_k127_1756161_3 YGGT family K02221 - - 0.000000000000000000000000000000001551 131.0
CSH2_k127_1759231_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.968e-228 717.0
CSH2_k127_1759231_1 ACT domain K00928 - 2.7.2.4 1.677e-202 637.0
CSH2_k127_1759231_2 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000003638 92.0
CSH2_k127_1761613_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000473 261.0
CSH2_k127_1761613_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005451 252.0
CSH2_k127_1761613_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000003146 246.0
CSH2_k127_1761613_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001087 222.0
CSH2_k127_1768235_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 299.0
CSH2_k127_1768235_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001278 205.0
CSH2_k127_1768235_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001641 202.0
CSH2_k127_1768235_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000002858 161.0
CSH2_k127_1768235_4 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000002439 154.0
CSH2_k127_1768235_5 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000006288 111.0
CSH2_k127_1768235_6 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001444 101.0
CSH2_k127_1768235_7 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001699 81.0
CSH2_k127_179279_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 336.0
CSH2_k127_179279_1 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000001364 189.0
CSH2_k127_179279_2 Domain of unknown function (DUF4388) - - - 0.0000000000000003239 83.0
CSH2_k127_1798636_0 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 364.0
CSH2_k127_180976_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 432.0
CSH2_k127_1822850_0 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 478.0
CSH2_k127_1839279_0 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 577.0
CSH2_k127_1839279_1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000002358 58.0
CSH2_k127_1841629_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 3.32e-227 711.0
CSH2_k127_1841629_1 endonuclease containing a URI domain K07461 - - 0.0003328 44.0
CSH2_k127_1868704_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 480.0
CSH2_k127_1868704_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 356.0
CSH2_k127_1868704_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 304.0
CSH2_k127_1868704_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000756 108.0
CSH2_k127_188237_0 ATPase BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 488.0
CSH2_k127_1895239_0 Sigma-54 factor interaction domain-containing protein K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 528.0
CSH2_k127_1899985_0 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 533.0
CSH2_k127_1899985_1 FliG middle domain K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 461.0
CSH2_k127_1899985_2 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000000000000000000000000001824 203.0
CSH2_k127_1899985_3 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000000000000000001207 137.0
CSH2_k127_1899985_4 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000005165 98.0
CSH2_k127_191618_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.496e-196 621.0
CSH2_k127_191618_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 334.0
CSH2_k127_191618_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000002759 186.0
CSH2_k127_191618_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000001301 161.0
CSH2_k127_191618_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000001163 127.0
CSH2_k127_1917626_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 327.0
CSH2_k127_1917626_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000004921 60.0
CSH2_k127_1917626_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.0000004394 53.0
CSH2_k127_1927902_0 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 297.0
CSH2_k127_1927902_1 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000003681 240.0
CSH2_k127_1927902_2 PBP superfamily domain K05772 - - 0.000000004514 57.0
CSH2_k127_1940282_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002038 263.0
CSH2_k127_1940282_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000001104 228.0
CSH2_k127_1940282_2 Protein of unknown function (DUF2934) - - - 0.0000000408 59.0
CSH2_k127_1943370_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 402.0
CSH2_k127_1943370_1 glutamate synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003409 282.0
CSH2_k127_1943370_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.000007943 48.0
CSH2_k127_1955450_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 373.0
CSH2_k127_1955450_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004052 219.0
CSH2_k127_1955450_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000001801 135.0
CSH2_k127_1955450_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000839 93.0
CSH2_k127_1963399_0 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009559 386.0
CSH2_k127_1970846_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 286.0
CSH2_k127_1970846_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000002154 63.0
CSH2_k127_1990452_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 375.0
CSH2_k127_1990452_1 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000004233 132.0
CSH2_k127_1996477_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 297.0
CSH2_k127_1996853_0 Protein of unknown function (DUF445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 309.0
CSH2_k127_200439_0 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 398.0
CSH2_k127_200439_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 321.0
CSH2_k127_2016085_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 347.0
CSH2_k127_2033334_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 369.0
CSH2_k127_2033334_1 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000005548 223.0
CSH2_k127_2033334_2 Essential for recycling GMP and indirectly, cGMP K00942,K01591 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 0.00000000000000000000000000000000000000000000000000000000006306 211.0
CSH2_k127_2033334_3 DUF167 K09131 - - 0.00000000000000000000000000000000000000005588 155.0
CSH2_k127_2033334_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000001638 148.0
CSH2_k127_2033334_5 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000000000003544 123.0
CSH2_k127_2033334_6 Belongs to the UPF0235 family K09131 - - 0.000000000000006313 78.0
CSH2_k127_2046094_0 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 515.0
CSH2_k127_2046094_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 374.0
CSH2_k127_2046094_2 formate dehydrogenase, beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 364.0
CSH2_k127_2046094_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000008211 164.0
CSH2_k127_2054537_0 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 374.0
CSH2_k127_2054537_1 Thiamine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009644 277.0
CSH2_k127_2054537_2 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000001416 216.0
CSH2_k127_2054537_3 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000000000563 160.0
CSH2_k127_2054537_4 energy transducer activity K03646,K03832 - - 0.000000000000001172 87.0
CSH2_k127_2060334_0 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 372.0
CSH2_k127_2060334_1 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000000000000001035 190.0
CSH2_k127_2060334_2 Enzyme of the cupin superfamily K06995 - - 0.00000000000000000000000000001363 119.0
CSH2_k127_2060334_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000432 91.0
CSH2_k127_2060334_4 - - - - 0.0000000004082 66.0
CSH2_k127_2072819_0 PFAM Transketolase central region K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 432.0
CSH2_k127_2072819_1 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 372.0
CSH2_k127_2072819_2 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 313.0
CSH2_k127_2079979_0 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 447.0
CSH2_k127_2079979_1 protein trimerization K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000004754 213.0
CSH2_k127_2079979_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000008442 178.0
CSH2_k127_2079979_3 Tetratricopeptide repeat - - - 0.00004116 48.0
CSH2_k127_2085773_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 353.0
CSH2_k127_2085773_1 - - - - 0.0000000009018 70.0
CSH2_k127_2087029_0 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 421.0
CSH2_k127_2087029_1 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000001019 209.0
CSH2_k127_2087029_2 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.000000000000000000000000001689 113.0
CSH2_k127_2092635_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 607.0
CSH2_k127_2092635_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 329.0
CSH2_k127_2092635_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003218 271.0
CSH2_k127_2092635_3 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000002004 177.0
CSH2_k127_2092635_4 Regulatory protein, FmdB family - - - 0.00000000002306 65.0
CSH2_k127_2102218_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 477.0
CSH2_k127_2102218_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 308.0
CSH2_k127_2102218_2 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.000000000000000000000000000000000000000002576 156.0
CSH2_k127_210280_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000002042 121.0
CSH2_k127_210280_1 Methionine biosynthesis protein MetW - - - 0.000000000000000000000002424 110.0
CSH2_k127_210280_2 Kdo2-lipid A biosynthetic process - - - 0.00006846 54.0
CSH2_k127_2111261_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 424.0
CSH2_k127_2111261_1 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000004306 192.0
CSH2_k127_2111261_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000002047 163.0
CSH2_k127_2111261_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000015 148.0
CSH2_k127_2111261_4 cheY-homologous receiver domain - - - 0.000000000000000000000000000003238 132.0
CSH2_k127_2111261_5 Sulfurtransferase TusA - - - 0.00000000000000000000001094 102.0
CSH2_k127_2111261_6 Diguanylate cyclase - - - 0.000000004419 62.0
CSH2_k127_2116240_0 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000001245 202.0
CSH2_k127_2116240_1 Protein of unknown function (DUF2878) - - - 0.0000000000008094 77.0
CSH2_k127_2118196_0 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 407.0
CSH2_k127_2118196_1 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 308.0
CSH2_k127_2118196_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000009231 222.0
CSH2_k127_2141958_0 Conserved region in glutamate synthase - - - 4.875e-281 870.0
CSH2_k127_2141958_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 416.0
CSH2_k127_2155486_0 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 490.0
CSH2_k127_2155486_1 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000002851 232.0
CSH2_k127_2155486_2 spore germination - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000001099 168.0
CSH2_k127_2155486_3 Transcriptional - - - 0.0000000000000000000000000000000000187 137.0
CSH2_k127_2155486_4 Type II secretion system protein B K02451 - - 0.000000000000000000000000002339 120.0
CSH2_k127_2160493_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 2.094e-256 802.0
CSH2_k127_2160493_1 FAD binding domain K05712 - 1.14.13.127 7.825e-211 672.0
CSH2_k127_2160493_2 von Willebrand factor (vWF) type A domain K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 368.0
CSH2_k127_2160493_3 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000003594 187.0
CSH2_k127_2160493_4 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000001576 144.0
CSH2_k127_2160493_5 Protein of unknown function (DUF2783) - - - 0.0000000000000000002331 90.0
CSH2_k127_2168003_0 Heat shock 70 kDa protein K04043 - - 4.307e-221 692.0
CSH2_k127_2168003_1 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 409.0
CSH2_k127_2168003_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000009245 130.0
CSH2_k127_2168424_0 response regulator K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 441.0
CSH2_k127_2168424_1 COGs COG4446 conserved - - - 0.00000000000000000000000000000003612 131.0
CSH2_k127_2168424_2 -acetyltransferase - - - 0.00000000000000000000003717 107.0
CSH2_k127_2168424_3 - - - - 0.000000001273 65.0
CSH2_k127_2173468_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 443.0
CSH2_k127_2173468_1 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.000000000000000000000000000000000000000000000000000000000000000000001869 243.0
CSH2_k127_2173468_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000001812 102.0
CSH2_k127_2173468_3 - - - - 0.000000000000006787 77.0
CSH2_k127_2181466_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1116.0
CSH2_k127_2186283_0 response regulator receiver K02481,K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 395.0
CSH2_k127_2186283_1 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000753 278.0
CSH2_k127_2186283_2 response regulator, receiver - - - 0.000000002209 62.0
CSH2_k127_2204041_0 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 381.0
CSH2_k127_2204041_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003262 280.0
CSH2_k127_2204041_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000001663 106.0
CSH2_k127_2213515_0 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 490.0
CSH2_k127_2213515_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000005898 139.0
CSH2_k127_2213515_2 Universal stress protein family - - - 0.0000000000000000002008 97.0
CSH2_k127_2234012_0 PFAM Radical SAM domain protein K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 415.0
CSH2_k127_2234012_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000007142 122.0
CSH2_k127_2234012_2 Major Facilitator Superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000006477 98.0
CSH2_k127_2257091_0 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004466 285.0
CSH2_k127_2257091_1 - - - - 0.00000000000000000000000000000000000000000000000001335 190.0
CSH2_k127_226903_0 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 451.0
CSH2_k127_226903_1 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000002671 161.0
CSH2_k127_2277127_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 544.0
CSH2_k127_2277127_1 Von Willebrand factor - - - 0.0000000000000000000000000000000000000000004463 176.0
CSH2_k127_2277127_2 cellulase activity K12287 - - 0.000000000000000000000001164 111.0
CSH2_k127_2285104_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 317.0
CSH2_k127_2285104_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000005135 164.0
CSH2_k127_2292618_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 8.063e-217 681.0
CSH2_k127_2292618_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000006448 154.0
CSH2_k127_2314844_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 557.0
CSH2_k127_2314844_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 329.0
CSH2_k127_2314844_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000002426 174.0
CSH2_k127_2333600_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.207e-238 747.0
CSH2_k127_2333600_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000003326 238.0
CSH2_k127_2333600_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000001651 145.0
CSH2_k127_2333600_3 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000191 130.0
CSH2_k127_2336658_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 552.0
CSH2_k127_2336658_1 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 336.0
CSH2_k127_2336658_2 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001078 270.0
CSH2_k127_2336658_3 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000000002 198.0
CSH2_k127_2336658_4 Protein of unknown function (DUF2892) - - - 0.000000000000000000003311 95.0
CSH2_k127_2338923_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 454.0
CSH2_k127_2338923_1 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000005922 185.0
CSH2_k127_2339223_0 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000000001278 228.0
CSH2_k127_2339223_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000002046 222.0
CSH2_k127_2339223_2 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000000000000000000006466 208.0
CSH2_k127_2357969_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 361.0
CSH2_k127_2357969_1 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000002114 79.0
CSH2_k127_2381892_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 2.5e-323 997.0
CSH2_k127_2390913_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 419.0
CSH2_k127_2390913_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000181 229.0
CSH2_k127_2390913_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000004043 94.0
CSH2_k127_2390913_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000001867 51.0
CSH2_k127_2395423_0 carbon starvation protein CstA K06200 - - 1.09e-313 970.0
CSH2_k127_2395423_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 530.0
CSH2_k127_2395423_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000001549 186.0
CSH2_k127_2395423_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000002323 161.0
CSH2_k127_2395423_4 nucleotide metabolic process - - - 0.00000000000000000000000000000001406 135.0
CSH2_k127_2405566_0 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005876 279.0
CSH2_k127_2405566_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000007886 139.0
CSH2_k127_2411150_0 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 339.0
CSH2_k127_2411150_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000006569 156.0
CSH2_k127_2411150_2 bacterial-type flagellum organization K02398 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009892,GO:0010556,GO:0010605,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031324,GO:0031326,GO:0032268,GO:0032269,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.000000000000000004754 88.0
CSH2_k127_241139_0 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 487.0
CSH2_k127_241139_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 403.0
CSH2_k127_241139_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 378.0
CSH2_k127_2421794_0 PFAM Class II aldolase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000009105 255.0
CSH2_k127_2421794_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000001234 78.0
CSH2_k127_242338_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1107.0
CSH2_k127_242338_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 445.0
CSH2_k127_242338_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 388.0
CSH2_k127_2432370_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 356.0
CSH2_k127_2432370_1 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000009116 117.0
CSH2_k127_2432370_2 ABC transporter K06158 - - 0.000000000000000000000000004667 113.0
CSH2_k127_243963_0 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 604.0
CSH2_k127_2445094_0 HAMP domain - - - 0.0000000000000000000000000000006112 137.0
CSH2_k127_2445094_1 Histidine kinase - - - 0.0000000000000000000006124 109.0
CSH2_k127_2445094_2 Histidine kinase - - - 0.0000000000001123 74.0
CSH2_k127_2465001_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1261.0
CSH2_k127_2465001_1 glyoxalase III activity - - - 0.00000000000000000000000000000000000000001714 157.0
CSH2_k127_2465001_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000009318 145.0
CSH2_k127_2478425_0 Ribonuclease E/G family K08301 - - 9.674e-210 661.0
CSH2_k127_2478425_1 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006915 251.0
CSH2_k127_2478425_2 lactate metabolic process K11473,K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000002928 248.0
CSH2_k127_2495372_0 Cellulose biosynthesis protein BcsQ K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008607 259.0
CSH2_k127_2495372_1 SRP54-type protein, GTPase domain K02404 - - 0.0000000000000000000000000000000000000000000000004514 187.0
CSH2_k127_2500141_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 376.0
CSH2_k127_2500141_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 349.0
CSH2_k127_2500141_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000245 280.0
CSH2_k127_2500141_3 PFAM TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000118 198.0
CSH2_k127_2500141_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000002358 143.0
CSH2_k127_2501607_0 COG1335 Amidases related to nicotinamidase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000006127 206.0
CSH2_k127_2501607_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000001946 199.0
CSH2_k127_2501607_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000007619 179.0
CSH2_k127_2501607_3 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000006109 124.0
CSH2_k127_2512918_0 Radical SAM superfamily K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 460.0
CSH2_k127_2512918_1 Aldehyde oxidase and xanthine dehydrogenase K00256 - 1.3.99.16 0.000000000000000000000000000000000000000000000000005717 185.0
CSH2_k127_2516865_0 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 550.0
CSH2_k127_2516865_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 354.0
CSH2_k127_2516865_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000001681 235.0
CSH2_k127_2516865_3 Drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000002442 101.0
CSH2_k127_2518007_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 322.0
CSH2_k127_2518007_1 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000356 165.0
CSH2_k127_2518476_0 phosphorelay signal transduction system K02584,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 415.0
CSH2_k127_2520944_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 3.786e-292 908.0
CSH2_k127_2520944_1 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000002599 63.0
CSH2_k127_2540145_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000001107 203.0
CSH2_k127_2540145_1 response regulator K07712 - - 0.00000000000000000000005162 101.0
CSH2_k127_2550702_0 lyase activity - - - 0.0000000000000000000000000000005647 137.0
CSH2_k127_2550849_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 411.0
CSH2_k127_2550849_1 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 305.0
CSH2_k127_2550849_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000001191 177.0
CSH2_k127_2550849_3 phosphorelay signal transduction system - - - 0.0000000000000000000000002566 109.0
CSH2_k127_2560845_0 ATP synthase alpha/beta family, beta-barrel domain K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 397.0
CSH2_k127_2560845_1 Flagellar assembly protein FliH K02411 - - 0.00000000000000005664 88.0
CSH2_k127_2563161_0 transmembrane signaling receptor activity K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 574.0
CSH2_k127_2563161_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 339.0
CSH2_k127_2577322_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000004986 227.0
CSH2_k127_2577322_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000005555 159.0
CSH2_k127_2577322_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000003396 95.0
CSH2_k127_2580111_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 469.0
CSH2_k127_2580111_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000004178 230.0
CSH2_k127_2594086_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 361.0
CSH2_k127_2601942_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 3.619e-198 640.0
CSH2_k127_2613631_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.637e-246 779.0
CSH2_k127_2613631_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 305.0
CSH2_k127_2613631_2 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002882 271.0
CSH2_k127_2613631_3 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000001009 232.0
CSH2_k127_2613631_4 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000147 241.0
CSH2_k127_2613631_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000004291 202.0
CSH2_k127_2613631_6 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000004873 79.0
CSH2_k127_2613631_8 Protein of unknown function (DUF1460) - - - 0.000203 53.0
CSH2_k127_2624436_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 503.0
CSH2_k127_2624436_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 291.0
CSH2_k127_2624436_2 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000004006 91.0
CSH2_k127_2624436_3 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000003363 50.0
CSH2_k127_2644664_0 Von Willebrand factor type A K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 461.0
CSH2_k127_2644664_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 288.0
CSH2_k127_2647792_0 - - - - 0.0000000000000000003872 98.0
CSH2_k127_2647792_2 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000108 87.0
CSH2_k127_2647792_4 PFAM ATP adenylyltransferase K00988 - 2.7.7.53 0.0000002247 53.0
CSH2_k127_2659759_0 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000002238 195.0
CSH2_k127_2659759_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000229 68.0
CSH2_k127_2663622_0 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 459.0
CSH2_k127_2663622_1 PFAM CBS domain containing protein K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007209 278.0
CSH2_k127_2663622_2 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000009466 166.0
CSH2_k127_2668976_0 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000008376 190.0
CSH2_k127_2668976_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000001887 156.0
CSH2_k127_267035_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 501.0
CSH2_k127_2671543_0 ferrous iron transmembrane transporter activity K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 599.0
CSH2_k127_2682741_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000001908 168.0
CSH2_k127_2689296_0 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 558.0
CSH2_k127_2701863_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 2.709e-200 642.0
CSH2_k127_2701863_1 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 410.0
CSH2_k127_2701863_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 382.0
CSH2_k127_2701863_3 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000002008 236.0
CSH2_k127_2701863_4 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000006182 162.0
CSH2_k127_2701863_5 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000000002129 139.0
CSH2_k127_2706028_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 366.0
CSH2_k127_2706028_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 344.0
CSH2_k127_273341_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 495.0
CSH2_k127_2775889_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 319.0
CSH2_k127_2775889_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002891 273.0
CSH2_k127_2775889_2 Ferredoxin K05337 - - 0.0000000000006623 70.0
CSH2_k127_2775889_3 Glycine zipper 2TM domain - - - 0.0005852 48.0
CSH2_k127_2784289_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.262e-221 690.0
CSH2_k127_2784289_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000001907 162.0
CSH2_k127_2789377_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 311.0
CSH2_k127_2789377_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000000003183 179.0
CSH2_k127_2793900_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000001933 220.0
CSH2_k127_2793900_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.0000000000000000000000000000000005312 134.0
CSH2_k127_2814278_0 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 572.0
CSH2_k127_2814278_1 Conserved carboxylase domain K01958 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 509.0
CSH2_k127_2814278_2 HD domain K07814 - - 0.0000000000000000000000000000000000000000003646 173.0
CSH2_k127_2814278_3 His Kinase A (phosphoacceptor) domain K13533 - 2.7.13.3 0.0000000000000000000002411 110.0
CSH2_k127_2826014_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 443.0
CSH2_k127_2826014_1 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000001509 256.0
CSH2_k127_2826014_2 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000001094 239.0
CSH2_k127_2826014_3 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.00000000000000000000000000000000000000000000002271 182.0
CSH2_k127_2826014_4 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0000000000000000000000000000283 118.0
CSH2_k127_2842444_0 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 478.0
CSH2_k127_2842444_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008647 350.0
CSH2_k127_2848526_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 430.0
CSH2_k127_2848526_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 307.0
CSH2_k127_2848526_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000003778 263.0
CSH2_k127_2855341_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 434.0
CSH2_k127_2861100_0 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 416.0
CSH2_k127_2861100_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.00000000000000000000005593 100.0
CSH2_k127_2882449_0 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 624.0
CSH2_k127_2882449_1 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000003266 162.0
CSH2_k127_2882449_2 CAAX protease self-immunity K07052 - - 0.00000001284 63.0
CSH2_k127_2896110_0 CHASE2 K01768 - 4.6.1.1 4.225e-202 644.0
CSH2_k127_29018_0 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 569.0
CSH2_k127_29018_1 shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000001248 184.0
CSH2_k127_29018_2 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000002374 162.0
CSH2_k127_2911798_0 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000002942 126.0
CSH2_k127_2911798_1 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.00000000000000000000000001524 110.0
CSH2_k127_2911798_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000271 91.0
CSH2_k127_2915809_0 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000003968 231.0
CSH2_k127_2915809_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000007227 152.0
CSH2_k127_2920525_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 486.0
CSH2_k127_2925221_0 TIGRFAM MauM NapG family ferredoxin-type protein K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 308.0
CSH2_k127_2925221_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 299.0
CSH2_k127_2925221_2 negative regulation of establishment of protein localization K02570 GO:0003674,GO:0005048,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032879,GO:0032880,GO:0033218,GO:0042277,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0051049,GO:0051051,GO:0051223,GO:0051224,GO:0065007,GO:0070201,GO:0090087,GO:1904950 - 0.000000000001365 70.0
CSH2_k127_2925264_0 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 1.883e-200 636.0
CSH2_k127_2925264_1 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000004278 169.0
CSH2_k127_2925264_2 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000003755 85.0
CSH2_k127_2937231_0 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009529 278.0
CSH2_k127_2937231_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005772 265.0
CSH2_k127_2937231_2 elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000007944 223.0
CSH2_k127_2948466_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002272 283.0
CSH2_k127_2948466_1 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step K05985,K07476 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 0.00000000000000000000000000000000000000000004474 166.0
CSH2_k127_2948466_2 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000003705 114.0
CSH2_k127_2948466_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000001772 72.0
CSH2_k127_294980_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 296.0
CSH2_k127_294980_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000001906 193.0
CSH2_k127_294980_2 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000001265 128.0
CSH2_k127_294980_3 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000001022 111.0
CSH2_k127_2965267_0 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003724 243.0
CSH2_k127_2965267_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000002764 216.0
CSH2_k127_2965401_0 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 343.0
CSH2_k127_2965401_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 352.0
CSH2_k127_2965401_2 CheY-like receiver, AAA-type ATPase and DNA-binding domain-containing response regulator - - - 0.000000000000000003495 89.0
CSH2_k127_2965401_3 - - - - 0.00000001738 62.0
CSH2_k127_297260_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.862e-266 854.0
CSH2_k127_297260_1 TPR repeat - - - 0.00000000000000000000006807 105.0
CSH2_k127_2972879_0 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000000003417 158.0
CSH2_k127_2984866_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 605.0
CSH2_k127_2987305_0 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 262.0
CSH2_k127_2987305_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.00000000000000000000000000000000000000000000000007862 181.0
CSH2_k127_3005429_0 Response regulator receiver - - - 2.391e-236 768.0
CSH2_k127_3014254_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 335.0
CSH2_k127_3022767_0 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001192 293.0
CSH2_k127_3022767_1 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000169 206.0
CSH2_k127_3022767_2 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000168 197.0
CSH2_k127_3033392_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 369.0
CSH2_k127_303767_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005585 247.0
CSH2_k127_303767_1 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000001031 204.0
CSH2_k127_3044840_0 helicase K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 325.0
CSH2_k127_3044840_1 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000002718 196.0
CSH2_k127_3052093_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 510.0
CSH2_k127_3052093_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 383.0
CSH2_k127_3052093_2 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000007547 214.0
CSH2_k127_3052093_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000001398 106.0
CSH2_k127_3052093_4 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000003312 67.0
CSH2_k127_3061900_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003105 272.0
CSH2_k127_3061900_1 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000281 190.0
CSH2_k127_3061900_2 - - - - 0.000000000000000000000000000001436 124.0
CSH2_k127_3061900_3 regulatory protein GntR HTH K03710 - - 0.00007574 48.0
CSH2_k127_3078202_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 7.022e-196 617.0
CSH2_k127_3078202_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 337.0
CSH2_k127_3078202_2 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003556 254.0
CSH2_k127_3085531_0 His Kinase A (phospho-acceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 445.0
CSH2_k127_3085531_1 Transcriptional regulatory protein, C terminal - - - 0.0000000003452 63.0
CSH2_k127_3094928_0 domain protein - - - 0.00000000000000009011 94.0
CSH2_k127_3126037_0 cysteine-tRNA ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001584 277.0
CSH2_k127_3126037_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000003288 159.0
CSH2_k127_3142977_0 Protein conserved in bacteria - - - 2.729e-236 757.0
CSH2_k127_3142977_1 Ribonuclease E/G family K08301 - - 0.00000136 50.0
CSH2_k127_3144022_0 SCO1/SenC - - - 0.00000000000000000000000000000000000000000000003233 177.0
CSH2_k127_3144022_1 FtsX-like permease family - - - 0.00000000000000000000000000000000000001158 151.0
CSH2_k127_3144022_2 PIN domain - - - 0.0000000000008283 71.0
CSH2_k127_314815_0 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 383.0
CSH2_k127_3151075_0 Multi-sensor signal transduction multi-kinase - - - 0.00000000000000000000000000000000000000000000000000104 204.0
CSH2_k127_3151075_1 - - - - 0.00000000000000000000000000000000000002247 146.0
CSH2_k127_3151075_2 Putative diguanylate phosphodiesterase - - - 0.0000001312 64.0
CSH2_k127_3170007_0 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 526.0
CSH2_k127_3170007_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000003188 244.0
CSH2_k127_3170007_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000007513 147.0
CSH2_k127_3170853_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 2.339e-196 620.0
CSH2_k127_3170853_1 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000003039 213.0
CSH2_k127_3170853_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000003246 187.0
CSH2_k127_3170853_3 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000006856 123.0
CSH2_k127_3177429_0 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 286.0
CSH2_k127_3177429_1 Cache domain - - - 0.000000000000000000000000000002981 132.0
CSH2_k127_3177429_2 - - - - 0.0000001587 55.0
CSH2_k127_3189521_0 coenzyme F390 synthetase K01912 - 6.2.1.30 2.434e-208 654.0
CSH2_k127_3189521_1 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 482.0
CSH2_k127_3189521_2 ACT domain - - - 0.000000000000000000000000000000000000000000000000000007623 193.0
CSH2_k127_3189521_3 - - - - 0.00000000000000000000000000000000000000234 151.0
CSH2_k127_3205542_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.252e-201 643.0
CSH2_k127_3205542_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000005236 159.0
CSH2_k127_3205542_3 Rubrerythrin - - - 0.000000000007628 72.0
CSH2_k127_3207196_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 388.0
CSH2_k127_3207196_1 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000000000000000000001095 124.0
CSH2_k127_321807_0 PINc domain ribonuclease K09006 - - 0.00000000000000000000000000000000000000000000000000000000000003862 222.0
CSH2_k127_321807_1 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000002562 138.0
CSH2_k127_321807_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000004291 132.0
CSH2_k127_321807_3 ACT domain protein - - - 0.000488 48.0
CSH2_k127_3223656_0 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000002515 236.0
CSH2_k127_3223656_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000003407 165.0
CSH2_k127_3223656_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000007288 105.0
CSH2_k127_3231956_0 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000000000000006415 165.0
CSH2_k127_3231956_1 endonuclease III - - - 0.000000000000000000000000000000000000001255 151.0
CSH2_k127_3237015_0 PFAM HhH-GPD superfamily base excision DNA repair protein K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000001228 226.0
CSH2_k127_3237015_1 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000003173 153.0
CSH2_k127_324984_0 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 281.0
CSH2_k127_324984_1 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000001344 228.0
CSH2_k127_3252960_0 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 318.0
CSH2_k127_3252960_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009707 271.0
CSH2_k127_3252960_2 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001374 269.0
CSH2_k127_3252960_3 - K02009 - - 0.0000000000000000000000508 104.0
CSH2_k127_3277635_0 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000004863 217.0
CSH2_k127_3277635_1 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.00000000000000000000000000000000000000000001002 172.0
CSH2_k127_3277635_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000004813 163.0
CSH2_k127_3277635_3 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000001383 149.0
CSH2_k127_3277635_4 Participates in both transcription termination and antitermination K02600 - - 0.0000001382 55.0
CSH2_k127_3289678_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 391.0
CSH2_k127_3289678_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 346.0
CSH2_k127_3289678_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000000006919 200.0
CSH2_k127_3289678_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000007483 144.0
CSH2_k127_3301198_0 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 424.0
CSH2_k127_3301198_1 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 412.0
CSH2_k127_3301198_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 353.0
CSH2_k127_3312797_0 - - - - 0.000000000000000000000000000000000000002837 154.0
CSH2_k127_3312797_1 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000004427 108.0
CSH2_k127_3312797_2 ThiS family - - - 0.000000000000000003003 88.0
CSH2_k127_3312797_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000008131 77.0
CSH2_k127_33210_0 C-terminal, D2-small domain, of ClpB protein K03694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 314.0
CSH2_k127_33210_1 translation initiation factor activity K03699 - - 0.0000000000000000000000000000000000000000000000000000004932 201.0
CSH2_k127_33210_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000001558 130.0
CSH2_k127_33210_3 Cysteine-rich secretory protein family - - - 0.0000000000000000000000006241 112.0
CSH2_k127_3338764_0 ATP synthase alpha/beta family, beta-barrel domain K02412 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 359.0
CSH2_k127_3338764_1 MgtE intracellular N domain - - - 0.0000003791 59.0
CSH2_k127_3338764_2 Flagellar export protein flij K02413 - - 0.0002323 49.0
CSH2_k127_3345039_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 254.0
CSH2_k127_3345039_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000001178 173.0
CSH2_k127_3347793_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.283e-208 664.0
CSH2_k127_3347793_1 PFAM Colicin V production protein K03558 - - 0.000000000000000102 87.0
CSH2_k127_3348492_0 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 1.65e-232 733.0
CSH2_k127_3366481_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 467.0
CSH2_k127_3366481_1 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 350.0
CSH2_k127_3366481_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437 - 2.1.1.185 0.0000000000000000000000000004979 120.0
CSH2_k127_3366481_3 Molecular chaperone. Has ATPase activity K04079 - - 0.000000005574 58.0
CSH2_k127_3368870_0 transferase activity, transferring glycosyl groups K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 297.0
CSH2_k127_3375015_0 Hydantoinase B/oxoprolinase K01469,K01474 - 3.5.2.14,3.5.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 499.0
CSH2_k127_3375015_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 332.0
CSH2_k127_3375015_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000004274 235.0
CSH2_k127_3375015_3 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000004853 121.0
CSH2_k127_3375141_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 1.908e-208 662.0
CSH2_k127_3375141_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 460.0
CSH2_k127_3375141_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000009944 49.0
CSH2_k127_3381415_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000007817 219.0
CSH2_k127_3381415_1 TPM domain - - - 0.000000000000000000000000000000000000000000001104 176.0
CSH2_k127_3381415_2 nucleotidyltransferase activity - - - 0.00000000000000004957 86.0
CSH2_k127_3409649_0 Surface antigen K07277 - - 8.071e-282 887.0
CSH2_k127_3409649_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 387.0
CSH2_k127_3409649_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 374.0
CSH2_k127_3409649_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000003165 216.0
CSH2_k127_3409649_4 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000006697 199.0
CSH2_k127_3409649_5 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.00000000000000000000002653 107.0
CSH2_k127_3422770_0 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 516.0
CSH2_k127_3422770_1 methyltransferase K03774,K03775 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 413.0
CSH2_k127_3422770_2 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000007654 165.0
CSH2_k127_3425852_0 Transcriptional regulator K11921,K19338 - - 0.0000000000000000000000000000000000000000000003926 175.0
CSH2_k127_3429203_0 Aminotransferase class I and II K14261 - - 2.186e-222 693.0
CSH2_k127_3429203_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 578.0
CSH2_k127_3429203_2 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000009439 218.0
CSH2_k127_3429203_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000001102 151.0
CSH2_k127_3429203_4 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000007743 94.0
CSH2_k127_3433237_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 331.0
CSH2_k127_3433237_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000005769 215.0
CSH2_k127_3433237_2 histidine kinase A domain protein - - - 0.00000000000000000000003929 113.0
CSH2_k127_3434528_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 545.0
CSH2_k127_3434528_1 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 342.0
CSH2_k127_3434528_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 302.0
CSH2_k127_3434528_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000004318 235.0
CSH2_k127_3434528_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000005904 196.0
CSH2_k127_3434528_5 PFAM Archaeal ATPase K06921 - - 0.000000000000000000000000000000000000000000000000005315 188.0
CSH2_k127_3465171_0 cobalt ion transport K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000007295 222.0
CSH2_k127_3465171_1 PFAM Nickel uptake substrate-specific transmembrane region K10094 - - 0.00000000000000000000000000000000013 149.0
CSH2_k127_3475454_0 UPF0210 protein K09157 - - 1.804e-224 702.0
CSH2_k127_3475454_1 PFAM amino acid-binding ACT domain protein K03567 - - 0.000000000000000000000000000000000000000000000000000000000000000011 228.0
CSH2_k127_3485886_0 Sigma-54 interaction domain - - - 1.756e-204 651.0
CSH2_k127_3485886_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001283 223.0
CSH2_k127_3487293_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 349.0
CSH2_k127_3487293_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000006681 105.0
CSH2_k127_3490999_0 ABC transporter transmembrane region K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 531.0
CSH2_k127_3490999_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001802 272.0
CSH2_k127_34918_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000004621 254.0
CSH2_k127_34918_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000006599 153.0
CSH2_k127_34918_2 thelarche K17081 - - 0.000000001097 59.0
CSH2_k127_3493935_0 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 372.0
CSH2_k127_3493935_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000004963 89.0
CSH2_k127_3510516_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 5.416e-263 827.0
CSH2_k127_3517186_0 Tetratricopeptide repeat K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003635 269.0
CSH2_k127_3517186_1 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003715 254.0
CSH2_k127_3517186_2 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000009934 169.0
CSH2_k127_3536085_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1251.0
CSH2_k127_3536085_1 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000001896 171.0
CSH2_k127_3538399_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 573.0
CSH2_k127_3546083_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 327.0
CSH2_k127_3546083_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000001177 171.0
CSH2_k127_3549397_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 587.0
CSH2_k127_3549397_1 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000000000000000003025 154.0
CSH2_k127_3549397_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000004388 106.0
CSH2_k127_3553529_0 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 365.0
CSH2_k127_3553529_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 343.0
CSH2_k127_3553529_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000005529 105.0
CSH2_k127_3553529_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00001017 47.0
CSH2_k127_3570194_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 365.0
CSH2_k127_3570194_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 353.0
CSH2_k127_3570194_2 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000101 203.0
CSH2_k127_3570194_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000004509 196.0
CSH2_k127_3573679_0 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 509.0
CSH2_k127_3573679_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 474.0
CSH2_k127_3573679_2 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 370.0
CSH2_k127_3573679_3 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 331.0
CSH2_k127_3573679_4 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003033 242.0
CSH2_k127_3573679_5 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000003158 231.0
CSH2_k127_3573679_6 Lysin motif K08307 - - 0.0000000000000000000000000000000000002183 151.0
CSH2_k127_3573679_7 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000001607 113.0
CSH2_k127_3582896_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 520.0
CSH2_k127_3582896_1 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000001181 196.0
CSH2_k127_3591480_0 Ftsk_gamma K03466 - - 1.353e-195 618.0
CSH2_k127_3591480_1 Ftsk_gamma K03466 - - 0.0000000000006172 78.0
CSH2_k127_3606033_0 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005805 281.0
CSH2_k127_3606033_1 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000001623 139.0
CSH2_k127_3612940_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 357.0
CSH2_k127_3664095_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 380.0
CSH2_k127_3664095_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 376.0
CSH2_k127_3664095_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 331.0
CSH2_k127_3676037_0 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 326.0
CSH2_k127_3676037_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 327.0
CSH2_k127_3681376_0 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 330.0
CSH2_k127_3681376_1 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.000000000000000000000000000000000008748 139.0
CSH2_k127_3706434_0 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 591.0
CSH2_k127_3716628_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 516.0
CSH2_k127_3716628_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 428.0
CSH2_k127_3716628_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 374.0
CSH2_k127_3716628_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009444 282.0
CSH2_k127_3716628_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000248 61.0
CSH2_k127_3724693_0 TonB dependent receptor K16092 - - 0.000000000000000000000000000000000000001892 155.0
CSH2_k127_3724693_1 ABC transporter (Permease) K02033 - - 0.000000000001954 72.0
CSH2_k127_3726311_0 type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000971 554.0
CSH2_k127_3738196_0 PFAM Dual specificity protein phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 322.0
CSH2_k127_3738196_1 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 0.0000000000000000000000000000000000000004264 151.0
CSH2_k127_3768197_0 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 514.0
CSH2_k127_3768197_1 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000004954 175.0
CSH2_k127_3788389_0 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 411.0
CSH2_k127_3788389_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000745 221.0
CSH2_k127_3788389_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000225 125.0
CSH2_k127_3803984_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 347.0
CSH2_k127_3811328_0 PFAM sigma-54 factor interaction domain-containing protein K06714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002407 281.0
CSH2_k127_3811328_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000001313 163.0
CSH2_k127_382218_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 576.0
CSH2_k127_3825678_0 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 432.0
CSH2_k127_3825678_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000007245 220.0
CSH2_k127_3825678_2 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000001043 105.0
CSH2_k127_3825678_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000006561 56.0
CSH2_k127_3826929_0 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000002384 229.0
CSH2_k127_3826929_1 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000001021 169.0
CSH2_k127_3827023_0 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 481.0
CSH2_k127_3827023_1 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 445.0
CSH2_k127_3827023_2 PFAM MgtC SapB transporter K07507 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005308 273.0
CSH2_k127_3827023_3 Rhodanese Homology Domain - - - 0.000006783 49.0
CSH2_k127_3846694_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 564.0
CSH2_k127_3846694_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 520.0
CSH2_k127_3846694_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000002926 229.0
CSH2_k127_3846694_3 - - - - 0.0000000000000000007453 89.0
CSH2_k127_3847940_0 Beta-Casp domain K07576 - - 2.943e-197 625.0
CSH2_k127_3847940_1 heme-binding sites - - - 0.0000000000000000000000000000000000000000000000002372 182.0
CSH2_k127_3847940_2 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000001822 136.0
CSH2_k127_3847940_3 - - - - 0.0000000006285 70.0
CSH2_k127_3849707_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005504 244.0
CSH2_k127_3849707_1 diguanylate cyclase - - - 0.000000000000000000001257 107.0
CSH2_k127_3849707_2 PhoQ Sensor - - - 0.0000000000000002073 88.0
CSH2_k127_3865992_0 glycolate transport K14393 - - 7.984e-217 683.0
CSH2_k127_3865992_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 485.0
CSH2_k127_3865992_2 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 441.0
CSH2_k127_3865992_3 Protein of unknown function, DUF485 - - - 0.00000000000000000000007406 101.0
CSH2_k127_3909507_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.423e-297 919.0
CSH2_k127_3909507_1 Peptidase S24-like K03100 - 3.4.21.89 0.00000000000136 70.0
CSH2_k127_391366_0 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006834 265.0
CSH2_k127_391366_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000003885 199.0
CSH2_k127_391366_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000271 136.0
CSH2_k127_391366_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000004894 94.0
CSH2_k127_3914182_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 329.0
CSH2_k127_3931556_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 403.0
CSH2_k127_3931556_1 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.00000000000000000000000000000000000000000000000000003235 193.0
CSH2_k127_3931556_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000006776 149.0
CSH2_k127_3931556_3 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000000004556 127.0
CSH2_k127_3957605_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000004216 199.0
CSH2_k127_3957605_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000001618 183.0
CSH2_k127_3959028_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 382.0
CSH2_k127_3959028_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 344.0
CSH2_k127_3972945_0 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 531.0
CSH2_k127_3972945_1 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000006692 115.0
CSH2_k127_3983213_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 531.0
CSH2_k127_3983213_1 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 312.0
CSH2_k127_3983213_2 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 306.0
CSH2_k127_3983213_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000003482 215.0
CSH2_k127_3983213_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000001379 196.0
CSH2_k127_3983213_5 Transcriptional regulatory protein, C terminal K07662 - - 0.0000000000007326 72.0
CSH2_k127_398937_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005782 284.0
CSH2_k127_398937_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000001994 105.0
CSH2_k127_398937_2 PFAM response regulator receiver - - - 0.00000000000001396 79.0
CSH2_k127_3992785_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 532.0
CSH2_k127_3992785_1 Phosphomethylpyrimidine kinase K00868,K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17 0.00000000000000000000000000000000000000000000000000006361 195.0
CSH2_k127_3997898_0 Caspase domain - - - 0.00000000001569 76.0
CSH2_k127_3997898_1 SH3, type 3 domain protein K01447 - 3.5.1.28 0.0001779 53.0
CSH2_k127_4006054_0 AsmA-like C-terminal region - - - 0.000000000000000000000000000528 132.0
CSH2_k127_4016257_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 411.0
CSH2_k127_4016257_1 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 300.0
CSH2_k127_4031096_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.000000000000000000000000000000002613 136.0
CSH2_k127_4031096_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000007601 66.0
CSH2_k127_4036000_0 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 402.0
CSH2_k127_4036000_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003453 258.0
CSH2_k127_4036000_2 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000000000002358 192.0
CSH2_k127_4036000_3 RNase H K03469 - 3.1.26.4 0.000000000000000000000000000000000001481 142.0
CSH2_k127_4036000_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000001197 120.0
CSH2_k127_4036594_0 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000004221 139.0
CSH2_k127_4036594_1 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000000001236 144.0
CSH2_k127_4068045_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 7.789e-213 665.0
CSH2_k127_4068045_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000339 143.0
CSH2_k127_4068045_2 thiolester hydrolase activity K03186 - 2.5.1.129 0.000000000000000000000001509 107.0
CSH2_k127_4068308_0 PFAM Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 401.0
CSH2_k127_4068308_1 PFAM PilT protein domain protein - - - 0.000001858 51.0
CSH2_k127_407613_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 479.0
CSH2_k127_407613_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000006947 131.0
CSH2_k127_4105932_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 310.0
CSH2_k127_4134203_0 Aconitase C-terminal domain K01681 - 4.2.1.3 7.559e-209 656.0
CSH2_k127_4134203_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 366.0
CSH2_k127_4143559_0 membrane K09133 - - 0.0000000000000000000000000000000000000000000000000001194 194.0
CSH2_k127_4143559_1 Domain of unknown function (DUF3842) - - - 0.000000000000000000000000000000000000000000000000003186 184.0
CSH2_k127_4143559_2 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000000000000002721 174.0
CSH2_k127_4143559_3 Psort location Cytoplasmic, score 8.96 K09949 - - 0.0000000000000000000000000000000003709 134.0
CSH2_k127_4152646_0 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000004496 221.0
CSH2_k127_4152646_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000865 63.0
CSH2_k127_4161850_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 591.0
CSH2_k127_416281_0 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 310.0
CSH2_k127_416281_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000238 94.0
CSH2_k127_4165887_0 Proposed homoserine kinase K15635 - 5.4.2.12 0.000000000000000000000000000000000001543 140.0
CSH2_k127_4165887_1 ThiS family K03636 - - 0.000000000000000000000000000000002361 132.0
CSH2_k127_4165887_2 JAB/MPN domain K21140 - 3.13.1.6 0.00000000000000000000000000000001123 131.0
CSH2_k127_4165887_3 NIL - - - 0.0000000000000000000000000356 110.0
CSH2_k127_4169971_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001212 278.0
CSH2_k127_4169971_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000004782 63.0
CSH2_k127_4174983_0 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 572.0
CSH2_k127_4174983_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 364.0
CSH2_k127_4174983_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000004005 51.0
CSH2_k127_4179964_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.916e-293 906.0
CSH2_k127_4179964_1 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002208 263.0
CSH2_k127_4179964_2 (Rhomboid) family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000000552 228.0
CSH2_k127_4179964_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000004834 142.0
CSH2_k127_4181536_0 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000002497 264.0
CSH2_k127_4181536_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000004458 200.0
CSH2_k127_4181536_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000003754 145.0
CSH2_k127_4181536_3 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000001594 111.0
CSH2_k127_4181536_4 PFAM methyltransferase K07755 - 2.1.1.137 0.0000008322 52.0
CSH2_k127_4181957_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 2.631e-240 754.0
CSH2_k127_4181957_1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 331.0
CSH2_k127_4181957_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000006958 225.0
CSH2_k127_4184145_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 379.0
CSH2_k127_4184145_1 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000001157 191.0
CSH2_k127_4184145_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000001591 162.0
CSH2_k127_4184145_3 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.0000000000005755 71.0
CSH2_k127_4196777_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 599.0
CSH2_k127_4196777_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008235 352.0
CSH2_k127_4196777_2 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001355 256.0
CSH2_k127_4196777_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000007452 143.0
CSH2_k127_4196777_4 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000000009421 141.0
CSH2_k127_4211735_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 306.0
CSH2_k127_4211735_1 Mo-molybdopterin cofactor metabolic process K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003024 249.0
CSH2_k127_4211735_2 PFAM histidine kinase, HAMP region domain protein - - - 0.0000002439 63.0
CSH2_k127_4215584_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 492.0
CSH2_k127_4215584_1 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004939 282.0
CSH2_k127_4215584_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000008679 212.0
CSH2_k127_4215584_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000001713 174.0
CSH2_k127_4215584_4 Protein of unknown function (DUF2905) - - - 0.000000000000000000004092 100.0
CSH2_k127_4215584_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000007389 48.0
CSH2_k127_4218164_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.692e-290 902.0
CSH2_k127_4242486_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 555.0
CSH2_k127_4242486_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 292.0
CSH2_k127_4242486_2 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000000002188 177.0
CSH2_k127_4242486_3 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000000000129 141.0
CSH2_k127_4242733_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004719 242.0
CSH2_k127_4242733_1 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000002809 221.0
CSH2_k127_4242733_2 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000437 215.0
CSH2_k127_4242733_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000001889 189.0
CSH2_k127_4262203_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 436.0
CSH2_k127_4262203_1 Peptidase family M23 - - - 0.000000000000000000001309 103.0
CSH2_k127_431181_0 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 353.0
CSH2_k127_431181_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000003043 171.0
CSH2_k127_431181_2 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000006346 137.0
CSH2_k127_431181_3 heat shock protein binding - - - 0.0000000000000000000000164 107.0
CSH2_k127_4341492_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 581.0
CSH2_k127_4341492_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 392.0
CSH2_k127_4342190_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007284 280.0
CSH2_k127_4342190_1 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000002691 72.0
CSH2_k127_4350646_0 Protein export membrane protein K03296,K18138 - - 0.0 1269.0
CSH2_k127_4378687_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000002375 222.0
CSH2_k127_4378687_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000002484 138.0
CSH2_k127_438176_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 456.0
CSH2_k127_438176_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 335.0
CSH2_k127_4390954_0 Pfam:Cache_2 K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 451.0
CSH2_k127_4390954_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 452.0
CSH2_k127_4390954_2 amino acid-binding ACT domain protein K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 292.0
CSH2_k127_4390954_3 TPR repeat - - - 0.00000000344 65.0
CSH2_k127_439647_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000001607 176.0
CSH2_k127_439647_1 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000000000001149 148.0
CSH2_k127_4399063_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 496.0
CSH2_k127_4399063_1 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000002059 154.0
CSH2_k127_4413526_0 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 314.0
CSH2_k127_4413526_1 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 298.0
CSH2_k127_4413526_2 PFAM ATP-grasp domain - - - 0.0000000000000000000005913 97.0
CSH2_k127_4413526_3 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000007774 56.0
CSH2_k127_4416479_0 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 396.0
CSH2_k127_4416479_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 358.0
CSH2_k127_4416479_2 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 350.0
CSH2_k127_4416479_3 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 319.0
CSH2_k127_4416479_4 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000001803 176.0
CSH2_k127_4416479_5 Putative regulatory protein - - - 0.00000000000000000000594 95.0
CSH2_k127_4424490_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 461.0
CSH2_k127_4424490_1 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 315.0
CSH2_k127_4424490_2 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000000003048 88.0
CSH2_k127_4424490_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000002913 61.0
CSH2_k127_4435377_0 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000001329 270.0
CSH2_k127_4435377_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000003195 132.0
CSH2_k127_4446958_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 438.0
CSH2_k127_4446958_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 368.0
CSH2_k127_4446958_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000007158 200.0
CSH2_k127_4483408_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009947 440.0
CSH2_k127_4483408_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000001598 145.0
CSH2_k127_4483408_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000001982 95.0
CSH2_k127_4493651_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.478e-195 618.0
CSH2_k127_4508369_0 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 347.0
CSH2_k127_4508369_1 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 323.0
CSH2_k127_4508369_2 - - - - 0.00000000000000000002201 93.0
CSH2_k127_4508369_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00001088 51.0
CSH2_k127_4525450_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.72e-216 681.0
CSH2_k127_4525450_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000008015 209.0
CSH2_k127_4525961_0 PFAM PHP domain - - - 0.000000000000000000000000000000000002503 146.0
CSH2_k127_4525961_1 Protein of unknown function (DUF3187) - - - 0.00000000000000000000237 107.0
CSH2_k127_4525961_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 0.00000000002165 66.0
CSH2_k127_4530733_0 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 530.0
CSH2_k127_4530733_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 316.0
CSH2_k127_4530733_2 nucleotidyltransferase activity K07075 - - 0.00000000000000001129 88.0
CSH2_k127_4530733_3 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000939 73.0
CSH2_k127_4531207_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 563.0
CSH2_k127_4531207_2 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000008026 84.0
CSH2_k127_4547282_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009223 384.0
CSH2_k127_4547282_1 PFAM glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000005626 263.0
CSH2_k127_4551636_0 Domain of unknown function (DUF4214) - - - 0.0000001059 65.0
CSH2_k127_4554001_0 Telomere recombination K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 336.0
CSH2_k127_4554001_1 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 288.0
CSH2_k127_4554001_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000001377 201.0
CSH2_k127_4554001_3 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000001528 199.0
CSH2_k127_4554001_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000004687 160.0
CSH2_k127_4554001_5 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000001134 130.0
CSH2_k127_4556591_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.142e-221 696.0
CSH2_k127_4556591_1 Nitroreductase - - - 8.972e-202 642.0
CSH2_k127_4556591_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 327.0
CSH2_k127_4556591_3 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000001026 177.0
CSH2_k127_4556591_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000002521 143.0
CSH2_k127_459127_0 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 7.763e-198 624.0
CSH2_k127_459127_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 328.0
CSH2_k127_459127_2 Nitrite and sulphite reductase 4Fe-4S K11180,K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000002156 226.0
CSH2_k127_4593124_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 485.0
CSH2_k127_4593124_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 451.0
CSH2_k127_4593124_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000112 71.0
CSH2_k127_4628304_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 342.0
CSH2_k127_4629716_0 NAD(P)H-binding K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 460.0
CSH2_k127_4629716_1 LysM domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 294.0
CSH2_k127_4629716_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000005013 246.0
CSH2_k127_4639594_0 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 582.0
CSH2_k127_4639594_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 532.0
CSH2_k127_4639594_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000003096 210.0
CSH2_k127_4639594_3 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000005829 68.0
CSH2_k127_4649188_0 Protein conserved in bacteria K06320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 314.0
CSH2_k127_465299_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 518.0
CSH2_k127_465299_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000008455 225.0
CSH2_k127_4665781_0 citrate synthase K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 379.0
CSH2_k127_4665781_1 - - - - 0.000000000000000000000000000000000000000002003 161.0
CSH2_k127_4665781_2 - - - - 0.0000000000000000000006028 96.0
CSH2_k127_4689769_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 431.0
CSH2_k127_4689769_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000002225 201.0
CSH2_k127_4707128_0 ABC transporter K06158 - - 1.737e-225 714.0
CSH2_k127_4707128_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000001951 122.0
CSH2_k127_4711186_0 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 484.0
CSH2_k127_4711186_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009548 261.0
CSH2_k127_4711186_2 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000005029 182.0
CSH2_k127_4722740_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.888e-205 655.0
CSH2_k127_4722740_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000001899 94.0
CSH2_k127_4728049_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 438.0
CSH2_k127_4728049_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 423.0
CSH2_k127_4728049_2 Protein of unknown function (DUF3124) - - - 0.000000000000000000000000000000000000000001138 162.0
CSH2_k127_4728049_3 Sodium hydrogen exchanger K03455 - - 0.0000000000000000000000000007214 121.0
CSH2_k127_4735168_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 391.0
CSH2_k127_4735168_1 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000001547 203.0
CSH2_k127_4735168_2 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000001535 166.0
CSH2_k127_4735168_3 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.0000000000000000000000000000002862 128.0
CSH2_k127_4735168_4 PFAM Thioredoxin K03671 - - 0.000000000000000000000003729 106.0
CSH2_k127_4735168_5 ABC transporter K09013 - - 0.00000000000009416 76.0
CSH2_k127_4762362_0 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000001063 213.0
CSH2_k127_4765099_0 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 321.0
CSH2_k127_4765099_1 nucleotidyltransferase activity - - - 0.00000000005278 66.0
CSH2_k127_4793020_0 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 554.0
CSH2_k127_4793020_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 294.0
CSH2_k127_4793020_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002659 291.0
CSH2_k127_4793020_3 PBS lyase HEAT-like repeat - - - 0.0001641 52.0
CSH2_k127_4802635_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000007179 192.0
CSH2_k127_4802635_1 COG1796 DNA polymerase IV (family X) K02347 - - 0.0002839 44.0
CSH2_k127_4808072_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000002164 224.0
CSH2_k127_4812476_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 5.217e-223 699.0
CSH2_k127_4812476_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 336.0
CSH2_k127_4812476_2 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000002048 241.0
CSH2_k127_4812476_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001333 196.0
CSH2_k127_4812476_4 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000297 197.0
CSH2_k127_4812476_5 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000003532 157.0
CSH2_k127_4812476_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000005592 128.0
CSH2_k127_4812476_7 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000002438 97.0
CSH2_k127_4812476_8 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000003753 70.0
CSH2_k127_4813840_0 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 369.0
CSH2_k127_4813840_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.000000000000000000000000000000000000000001246 167.0
CSH2_k127_4813840_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000001842 101.0
CSH2_k127_4813877_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 320.0
CSH2_k127_4818899_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.239e-294 911.0
CSH2_k127_4818899_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 353.0
CSH2_k127_4818899_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 337.0
CSH2_k127_4818899_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 306.0
CSH2_k127_4818899_4 ATP synthase subunit J K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000002131 239.0
CSH2_k127_4818899_5 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.00000000000000002447 89.0
CSH2_k127_4827770_0 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 310.0
CSH2_k127_487985_0 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 458.0
CSH2_k127_4891501_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 517.0
CSH2_k127_4891501_1 YbbR-like protein - - - 0.00000000000000000000000000000000000000000000000000000397 197.0
CSH2_k127_4891501_2 Competence protein K02238 - - 0.0000000000000000000000000009168 124.0
CSH2_k127_489260_0 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 320.0
CSH2_k127_4914878_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001278 283.0
CSH2_k127_4914878_2 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000007844 62.0
CSH2_k127_4917219_0 Uncharacterized protein family (UPF0051) K07033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 334.0
CSH2_k127_4917219_1 PFAM ABC transporter related K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002532 251.0
CSH2_k127_4917219_2 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000776 128.0
CSH2_k127_4917219_3 DsrC like protein - - - 0.0006911 42.0
CSH2_k127_492811_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 304.0
CSH2_k127_492811_1 - - - - 0.000000000000000000001563 99.0
CSH2_k127_4943794_0 Wzt C-terminal domain K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 374.0
CSH2_k127_4943794_1 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.00000000000000000000000000008307 117.0
CSH2_k127_4943794_2 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000004046 63.0
CSH2_k127_4945070_0 ligase activity K01469,K01473,K01474,K10701,K10855 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016885,GO:0017144,GO:0018710,GO:0042180,GO:0043443,GO:0044237,GO:0044281,GO:0071704,GO:1901568,GO:1902224 3.5.2.14,3.5.2.9,6.4.1.6,6.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 321.0
CSH2_k127_4957643_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 8.339e-197 616.0
CSH2_k127_4957643_1 L-phenylalanine transmembrane transporter activity K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 487.0
CSH2_k127_4957643_2 leucine import across plasma membrane K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 455.0
CSH2_k127_4957643_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 332.0
CSH2_k127_4957643_4 branched-chain amino acid transmembrane transporter activity K01996 - - 0.0000000000000000000000000000000000000000000000000001088 189.0
CSH2_k127_4965503_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000003016 162.0
CSH2_k127_4965503_1 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000001222 72.0
CSH2_k127_4965503_2 - - - - 0.000000000002549 72.0
CSH2_k127_4965503_3 - - - - 0.00000000001258 67.0
CSH2_k127_4965503_4 PFAM pentapeptide repeat protein - - - 0.00007233 49.0
CSH2_k127_4996054_0 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 550.0
CSH2_k127_4996054_1 MazG-like family - - - 0.000000000000000000000000000000000001431 142.0
CSH2_k127_4996054_2 Dodecin K09165 - - 0.0000000000000000001575 89.0
CSH2_k127_4998250_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 517.0
CSH2_k127_5002608_0 B3/4 domain K01890 - 6.1.1.20 6.913e-194 625.0
CSH2_k127_5028204_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002725 272.0
CSH2_k127_5028204_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000002358 143.0
CSH2_k127_5030493_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 606.0
CSH2_k127_5030493_1 - - - - 0.00000000000004053 77.0
CSH2_k127_503390_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000003869 226.0
CSH2_k127_503390_1 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000009248 160.0
CSH2_k127_503390_2 Smr domain - - - 0.00000000000000002521 89.0
CSH2_k127_5038368_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 391.0
CSH2_k127_5038368_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000004342 219.0
CSH2_k127_5038368_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 0.00000000000000000000003942 101.0
CSH2_k127_5038368_3 - - - - 0.0000009881 50.0
CSH2_k127_5044196_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 9.184e-254 796.0
CSH2_k127_5044196_1 membrane K00389 - - 0.0000000000000000000000000000000000000009155 151.0
CSH2_k127_5045134_0 Protein involved in outer membrane biogenesis - - - 5.852e-256 830.0
CSH2_k127_5046046_0 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000003635 145.0
CSH2_k127_5046046_1 B3/4 domain K01890 - 6.1.1.20 0.000000000000000000000001047 107.0
CSH2_k127_5057135_0 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000007206 216.0
CSH2_k127_5057135_1 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000006453 144.0
CSH2_k127_5057135_4 PFAM YeeE YedE family (DUF395) K07112 - - 0.0000006864 51.0
CSH2_k127_507922_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 359.0
CSH2_k127_507922_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 312.0
CSH2_k127_507922_2 DNA polymerase A domain K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 296.0
CSH2_k127_507922_3 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001075 291.0
CSH2_k127_507922_4 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000009118 248.0
CSH2_k127_507922_5 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000003183 179.0
CSH2_k127_507922_6 energy transducer activity K03832 - - 0.00000000000000000000000000000000000000000001436 172.0
CSH2_k127_507922_7 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000001161 164.0
CSH2_k127_5091548_0 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000003053 240.0
CSH2_k127_5091548_1 Ammonium Transporter Family K03320 - - 0.00000000000000000000000005362 110.0
CSH2_k127_5100641_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 419.0
CSH2_k127_5121220_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 597.0
CSH2_k127_5121220_1 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 321.0
CSH2_k127_5125346_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 516.0
CSH2_k127_5136561_0 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 429.0
CSH2_k127_5136561_1 pseudouridine synthase activity K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000002944 269.0
CSH2_k127_5136561_2 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000002413 171.0
CSH2_k127_5143475_0 DHHA2 domain K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 449.0
CSH2_k127_5143475_1 Protein of unknown function (DUF3373) - - - 0.000000000000000000000000000000000000000000000000000000000003292 217.0
CSH2_k127_5152236_0 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000004623 256.0
CSH2_k127_5152236_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000007737 214.0
CSH2_k127_5152236_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000002587 171.0
CSH2_k127_5152236_3 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000005407 166.0
CSH2_k127_5152236_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000007883 152.0
CSH2_k127_5152236_5 HNH nucleases - - - 0.000000000000000000000000000000000134 138.0
CSH2_k127_5152236_6 Protein of unknown function (DUF507) - - - 0.000000000000000000000000002701 113.0
CSH2_k127_5152236_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000007345 72.0
CSH2_k127_5163303_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.466e-207 658.0
CSH2_k127_5163303_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 545.0
CSH2_k127_5163303_2 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 447.0
CSH2_k127_5163303_3 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 359.0
CSH2_k127_5163303_4 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000004252 196.0
CSH2_k127_5168175_0 Permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 369.0
CSH2_k127_5168175_1 Cupin domain - - - 0.0000000000000000000000000000000000000000001452 162.0
CSH2_k127_5168175_2 Psort location Cytoplasmic, score - - - 0.0000000000000004251 85.0
CSH2_k127_5194022_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 442.0
CSH2_k127_5194022_1 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 336.0
CSH2_k127_5213944_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 527.0
CSH2_k127_5213944_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000005412 108.0
CSH2_k127_5216310_0 Telomere recombination K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 436.0
CSH2_k127_5216310_1 C-terminus of AA_permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 356.0
CSH2_k127_5216310_3 transferase activity, transferring glycosyl groups - - - 0.000000000005518 72.0
CSH2_k127_52205_0 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 434.0
CSH2_k127_52205_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 402.0
CSH2_k127_52205_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000001449 156.0
CSH2_k127_52205_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000002119 136.0
CSH2_k127_5221606_0 Bacterial regulatory protein, Fis family K07715 - - 3.179e-209 658.0
CSH2_k127_5221606_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000005946 218.0
CSH2_k127_5237723_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000436 209.0
CSH2_k127_5237723_1 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000007049 106.0
CSH2_k127_5249095_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 357.0
CSH2_k127_5249095_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000001172 211.0
CSH2_k127_5249095_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000000001681 173.0
CSH2_k127_5249191_0 Molecular chaperone. Has ATPase activity K04079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 364.0
CSH2_k127_5270944_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 536.0
CSH2_k127_5270944_1 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000001101 186.0
CSH2_k127_5270944_2 - - - - 0.000008166 53.0
CSH2_k127_5273773_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000007531 183.0
CSH2_k127_5273773_1 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000002283 167.0
CSH2_k127_5273773_2 Tetratricopeptide repeat - - - 0.00002387 48.0
CSH2_k127_5293931_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 308.0
CSH2_k127_5293931_1 ABC-type multidrug transport system ATPase K01990,K11050 - - 0.000000000000000000000000000000000000000000000000000000000000000001106 231.0
CSH2_k127_5324603_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.462e-216 677.0
CSH2_k127_5324603_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 354.0
CSH2_k127_5324603_2 Planctomycete cytochrome C - - - 0.0000000715 55.0
CSH2_k127_5333199_0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000002898 226.0
CSH2_k127_5333199_1 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000001607 182.0
CSH2_k127_5333199_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000000000000006814 189.0
CSH2_k127_5362338_0 PFAM Mannosyl oligosaccharide glucosidase - - - 0.000000000000000000000000000000000000000000000000000000000003535 210.0
CSH2_k127_5366623_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 496.0
CSH2_k127_5366623_1 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000001237 126.0
CSH2_k127_536784_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 351.0
CSH2_k127_536784_1 PFAM periplasmic solute binding protein K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001707 252.0
CSH2_k127_536784_2 Glycoprotease family K14742 - - 0.00000000000000000000000000000000000000000000000000000003233 203.0
CSH2_k127_536784_3 PFAM ABC transporter related K11710 - - 0.000000000000000000000000157 111.0
CSH2_k127_536784_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000002439 60.0
CSH2_k127_5373844_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 416.0
CSH2_k127_5373844_1 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 364.0
CSH2_k127_5373844_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000003318 215.0
CSH2_k127_5373844_3 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.000000000000000000004283 96.0
CSH2_k127_5380619_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 579.0
CSH2_k127_5438320_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001079 284.0
CSH2_k127_5438320_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000001176 244.0
CSH2_k127_5438320_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000003974 175.0
CSH2_k127_5440869_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 402.0
CSH2_k127_5440869_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000001173 158.0
CSH2_k127_5440869_2 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000007177 144.0
CSH2_k127_5443087_0 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 443.0
CSH2_k127_5443087_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000009947 58.0
CSH2_k127_5449598_0 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 377.0
CSH2_k127_5449598_1 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 317.0
CSH2_k127_5449598_2 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000008381 216.0
CSH2_k127_5449598_3 PilZ domain - - - 0.000000000000000000000000000000000000000000393 164.0
CSH2_k127_5449598_4 MotA/TolQ/ExbB proton channel family K02556 - - 0.00000000000000302 76.0
CSH2_k127_5455046_0 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 436.0
CSH2_k127_5455046_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000002179 91.0
CSH2_k127_5461186_0 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 308.0
CSH2_k127_5497193_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 385.0
CSH2_k127_5497193_1 Bacterial regulatory protein, Fis family K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004365 274.0
CSH2_k127_5497193_2 beta-lactamase activity K07126 - - 0.000000000000004123 78.0
CSH2_k127_5504024_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003231 282.0
CSH2_k127_5504024_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000004593 205.0
CSH2_k127_5504024_2 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000006018 182.0
CSH2_k127_5504024_3 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.00000000001008 75.0
CSH2_k127_5506907_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 327.0
CSH2_k127_5506907_1 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000004745 62.0
CSH2_k127_5547044_0 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 447.0
CSH2_k127_5547044_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 355.0
CSH2_k127_5547044_2 Universal stress protein family K07090 - - 0.000000000000000000000000000000000000000000000001548 190.0
CSH2_k127_5547044_3 - - - - 0.0000000000000000000000000000000000000000007314 161.0
CSH2_k127_5547044_4 response regulator - - - 0.0000000000000000000000000000000005713 136.0
CSH2_k127_5547044_5 phosphorelay signal transduction system - - - 0.0000000000000000000000000000001024 134.0
CSH2_k127_5547044_6 PFAM response regulator receiver - - - 0.0000000000000000000000001919 113.0
CSH2_k127_5547044_7 Histidine kinase - - - 0.00000000000000000000009262 107.0
CSH2_k127_5547044_8 Universal stress protein family K07090 - - 0.0000000000000000001878 93.0
CSH2_k127_5564095_0 Heavy metal transport detoxification protein K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 567.0
CSH2_k127_5564095_1 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 295.0
CSH2_k127_5564095_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003309 256.0
CSH2_k127_5577110_0 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 329.0
CSH2_k127_5577110_1 PFAM histone deacetylase superfamily K04768 - - 0.0000000000000000000000000000000000000000101 156.0
CSH2_k127_5577110_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000001375 141.0
CSH2_k127_5580951_0 Metallopeptidase family M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002555 288.0
CSH2_k127_5580951_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007329 280.0
CSH2_k127_5580951_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000001716 123.0
CSH2_k127_5580951_3 Tetratricopeptide repeat - - - 0.00002712 53.0
CSH2_k127_5608284_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.392e-309 955.0
CSH2_k127_5608284_1 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 520.0
CSH2_k127_5608284_2 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001386 265.0
CSH2_k127_5608284_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000005929 133.0
CSH2_k127_5608284_4 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.0000000000000000000001169 98.0
CSH2_k127_5608284_5 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000006605 99.0
CSH2_k127_5608284_6 Universal stress protein family - - - 0.00000000000000000001305 96.0
CSH2_k127_5608284_7 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000007507 72.0
CSH2_k127_5629000_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1142.0
CSH2_k127_5629000_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 493.0
CSH2_k127_5654829_0 Bacterial regulatory proteins, crp family - - - 0.0000000000000000000000000000000000007225 143.0
CSH2_k127_5654829_1 - - - - 0.0000004745 62.0
CSH2_k127_5664189_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 597.0
CSH2_k127_5673090_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 490.0
CSH2_k127_5673090_1 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000000005561 127.0
CSH2_k127_5673090_2 Predicted permease YjgP/YjgQ family K07091 - - 0.0000003022 54.0
CSH2_k127_5677363_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 379.0
CSH2_k127_5677363_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004744 262.0
CSH2_k127_5677363_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000001303 140.0
CSH2_k127_5714105_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 528.0
CSH2_k127_5714105_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 366.0
CSH2_k127_5714105_2 metal-dependent enzyme K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 309.0
CSH2_k127_5714105_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000004855 228.0
CSH2_k127_5714105_4 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000006933 116.0
CSH2_k127_5714105_5 YHYH protein - - - 0.00000000000000000000006446 115.0
CSH2_k127_571596_0 Domain of unknown function (DUF4139) - - - 3.233e-194 617.0
CSH2_k127_571596_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000046 187.0
CSH2_k127_571596_2 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 0.00000000000000000000000000000000000000001023 155.0
CSH2_k127_5718069_0 CbbQ/NirQ/NorQ C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 396.0
CSH2_k127_5718069_1 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000002746 194.0
CSH2_k127_5718069_2 PFAM von Willebrand factor type A domain K02448 - - 0.00000000000000000000009343 111.0
CSH2_k127_5719448_0 Mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 413.0
CSH2_k127_5722929_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 4.833e-209 655.0
CSH2_k127_5722929_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 445.0
CSH2_k127_5722929_2 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000007097 201.0
CSH2_k127_5722929_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000000002589 182.0
CSH2_k127_57399_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.733e-309 966.0
CSH2_k127_57399_1 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000008764 250.0
CSH2_k127_57399_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000006141 157.0
CSH2_k127_57399_3 - - - - 0.000000000000000001961 92.0
CSH2_k127_57399_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000001143 85.0
CSH2_k127_57399_6 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000007405 59.0
CSH2_k127_57418_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 424.0
CSH2_k127_5742617_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 515.0
CSH2_k127_5742617_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 471.0
CSH2_k127_5748147_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 288.0
CSH2_k127_5748147_1 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003106 259.0
CSH2_k127_5748147_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000003951 170.0
CSH2_k127_5752906_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 326.0
CSH2_k127_5752906_1 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000001965 226.0
CSH2_k127_5753724_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1586.0
CSH2_k127_5753724_1 PFAM phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 522.0
CSH2_k127_5753724_2 Hydrogenase (NiFe) small subunit HydA K00534,K06282,K18008 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.12.2.1,1.12.7.2,1.12.99.6 0.0000000000000000000000000000000993 134.0
CSH2_k127_5759042_0 Protein of unknown function DUF262 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 496.0
CSH2_k127_5759042_1 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002979 252.0
CSH2_k127_5759042_2 - - - - 0.000000000000000000000000001699 126.0
CSH2_k127_5759946_0 response to heat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 570.0
CSH2_k127_5759946_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 517.0
CSH2_k127_5776770_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 7.636e-216 685.0
CSH2_k127_5776770_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000002969 227.0
CSH2_k127_5776770_2 response to heat - - - 0.000000000000000000000000000000000000000001834 156.0
CSH2_k127_5778307_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000613 166.0
CSH2_k127_5778307_1 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000003292 131.0
CSH2_k127_5829580_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.796e-227 729.0
CSH2_k127_5829580_1 gas vesicle protein - - - 0.000000000000000002977 89.0
CSH2_k127_5834160_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.527e-202 635.0
CSH2_k127_5834160_1 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000002446 87.0
CSH2_k127_5834160_2 DNA protecting protein DprA K04096 - - 0.000000001683 65.0
CSH2_k127_5848807_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 514.0
CSH2_k127_5848807_1 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 452.0
CSH2_k127_5848807_2 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000002305 89.0
CSH2_k127_5854563_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 341.0
CSH2_k127_5854563_1 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000001504 135.0
CSH2_k127_5861969_0 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 327.0
CSH2_k127_5861969_1 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.000000000000000000001168 97.0
CSH2_k127_5892635_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.26e-265 829.0
CSH2_k127_5892635_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000002223 220.0
CSH2_k127_5893419_0 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 437.0
CSH2_k127_5893419_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 400.0
CSH2_k127_5893419_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000003134 259.0
CSH2_k127_5915363_0 sigma factor activity K02405,K03093 - - 0.0000000000000000000000000000000000000000000000000000000007015 209.0
CSH2_k127_5915363_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000004421 196.0
CSH2_k127_5915363_2 Cellulose biosynthesis protein BcsQ K04562 - - 0.0000000000000000000000000000000000000000007055 160.0
CSH2_k127_5923726_0 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 395.0
CSH2_k127_5929662_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 445.0
CSH2_k127_5929662_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000246 145.0
CSH2_k127_593701_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001266 278.0
CSH2_k127_593701_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000001912 240.0
CSH2_k127_5939255_0 GTP-binding protein TypA K06207 - - 3.599e-258 808.0
CSH2_k127_5939255_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 7.166e-237 753.0
CSH2_k127_5939255_2 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 285.0
CSH2_k127_5939255_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000002523 267.0
CSH2_k127_5943383_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004325 280.0
CSH2_k127_5943383_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000002057 250.0
CSH2_k127_5943383_2 response regulator - - - 0.0000000000000000009062 86.0
CSH2_k127_5948763_0 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.00000000000000000000000000000000000000004432 160.0
CSH2_k127_5948763_1 PFAM NAD dependent epimerase dehydratase family - - - 0.000000000000000000000000000000000000004753 155.0
CSH2_k127_5948763_2 - - - - 0.00000000002027 72.0
CSH2_k127_5992482_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 480.0
CSH2_k127_5992482_1 Protein of unknown function (DUF3373) - - - 0.000000000000000000000000000000000000000000000000000000000000000665 229.0
CSH2_k127_5992482_2 Protein of unknown function (DUF3373) - - - 0.000000000000000000000003655 108.0
CSH2_k127_6034135_0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 360.0
CSH2_k127_6034135_1 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006157 265.0
CSH2_k127_6034135_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000728 66.0
CSH2_k127_6034135_3 Regulatory protein, FmdB family - - - 0.0000000006251 62.0
CSH2_k127_6035072_0 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000582 248.0
CSH2_k127_6035072_1 Flagellar motor switch protein FliM K02416 - - 0.000000000000000000000000000000000000000000000000000000002087 203.0
CSH2_k127_6035072_2 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000000000000000000000000000000004447 140.0
CSH2_k127_6073047_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 444.0
CSH2_k127_6073047_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 338.0
CSH2_k127_6079330_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 451.0
CSH2_k127_6079330_1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 368.0
CSH2_k127_6079330_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000002114 177.0
CSH2_k127_6079330_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000003917 160.0
CSH2_k127_6079330_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000003847 151.0
CSH2_k127_6079330_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000009549 117.0
CSH2_k127_6104282_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 603.0
CSH2_k127_6119082_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 564.0
CSH2_k127_6119082_1 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 475.0
CSH2_k127_6119082_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000001943 49.0
CSH2_k127_6119082_3 - - - - 0.0005921 45.0
CSH2_k127_6126310_0 protein secretion K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001841 287.0
CSH2_k127_6126310_1 Surface antigen K07277 - - 0.00000000000000000000000000000001068 132.0
CSH2_k127_6126310_2 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000008514 102.0
CSH2_k127_6136318_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.211e-221 691.0
CSH2_k127_6136318_1 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 298.0
CSH2_k127_6136318_2 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000005194 176.0
CSH2_k127_6138547_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1006.0
CSH2_k127_6138547_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.078e-231 724.0
CSH2_k127_6152571_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 334.0
CSH2_k127_6152571_1 - - - - 0.00000000000000000000002397 102.0
CSH2_k127_6152571_2 HDOD domain - - - 0.0000000000000000000003952 98.0
CSH2_k127_6152571_3 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.0000000000000000000006176 103.0
CSH2_k127_6163683_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 518.0
CSH2_k127_6163683_1 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002108 269.0
CSH2_k127_6175739_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000004051 244.0
CSH2_k127_6184270_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 1.622e-211 666.0
CSH2_k127_6184270_1 lactate/malate dehydrogenase, alpha/beta C-terminal domain K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 383.0
CSH2_k127_6198214_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 561.0
CSH2_k127_6198214_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 301.0
CSH2_k127_6198214_2 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 296.0
CSH2_k127_6198214_3 Cytochrome b/b6/petB K03887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006303 273.0
CSH2_k127_6198214_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000004025 162.0
CSH2_k127_6198214_5 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000000001349 119.0
CSH2_k127_6198214_6 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000004625 123.0
CSH2_k127_6198214_8 protein histidine kinase activity - - - 0.000000009086 68.0
CSH2_k127_6205324_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 6.809e-209 657.0
CSH2_k127_6205324_1 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001126 229.0
CSH2_k127_6205324_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000437 184.0
CSH2_k127_6205324_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000271 143.0
CSH2_k127_6205324_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000006675 139.0
CSH2_k127_6210378_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 605.0
CSH2_k127_6210378_1 PFAM PfkB K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 397.0
CSH2_k127_6210378_2 Mn2 dependent serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001872 246.0
CSH2_k127_6210378_3 Thioesterase K18700 - 3.1.2.29 0.0003561 48.0
CSH2_k127_622161_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 589.0
CSH2_k127_6224603_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 514.0
CSH2_k127_6224603_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 404.0
CSH2_k127_6224603_10 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000003079 51.0
CSH2_k127_6224603_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 337.0
CSH2_k127_6224603_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 311.0
CSH2_k127_6224603_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000436 239.0
CSH2_k127_6224603_5 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000003915 239.0
CSH2_k127_6224603_6 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000003603 170.0
CSH2_k127_6224603_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000003921 153.0
CSH2_k127_6224603_8 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000223 151.0
CSH2_k127_6224603_9 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002596 114.0
CSH2_k127_6244567_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.634e-259 813.0
CSH2_k127_6244567_1 - - - - 0.0000000004153 63.0
CSH2_k127_6247494_0 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002992 275.0
CSH2_k127_6247494_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000002484 247.0
CSH2_k127_6247494_2 photoreceptor activity - - - 0.0000000000000000000000000000000000000000000364 184.0
CSH2_k127_6256370_0 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 310.0
CSH2_k127_6256370_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000008073 160.0
CSH2_k127_6270830_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 481.0
CSH2_k127_6280928_0 Aminotransferase class-III K01845 - 5.4.3.8 3.306e-202 636.0
CSH2_k127_6280928_1 protein complex oligomerization - - - 0.00000000000000009452 85.0
CSH2_k127_6313687_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 6.536e-251 781.0
CSH2_k127_6313687_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 306.0
CSH2_k127_6313687_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000003583 164.0
CSH2_k127_6313687_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000004239 90.0
CSH2_k127_6323685_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 477.0
CSH2_k127_6323685_1 Translation initiation factor IF-3, C-terminal domain K02520 - - 0.00000000000000000000000000000000000000000000000000001768 193.0
CSH2_k127_6323685_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000007632 168.0
CSH2_k127_6323685_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000004053 119.0
CSH2_k127_6323685_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000009283 93.0
CSH2_k127_6330452_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 353.0
CSH2_k127_6342214_0 KR domain - - - 0.00000000000000000000000000000000000000000007433 171.0
CSH2_k127_6342214_1 Phosphopantetheine attachment site - - - 0.0000000000000000001896 93.0
CSH2_k127_6350819_0 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 560.0
CSH2_k127_6350819_1 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000129 301.0
CSH2_k127_6358411_0 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 311.0
CSH2_k127_6358411_1 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.0000000000000001943 79.0
CSH2_k127_637640_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 1.132e-309 973.0
CSH2_k127_637640_1 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 312.0
CSH2_k127_6403336_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 4.463e-257 810.0
CSH2_k127_6403336_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 7.134e-223 710.0
CSH2_k127_6403336_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 473.0
CSH2_k127_6403336_3 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 391.0
CSH2_k127_6403336_4 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003588 235.0
CSH2_k127_6403336_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000002175 156.0
CSH2_k127_6403336_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000001875 118.0
CSH2_k127_6429678_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 571.0
CSH2_k127_6429678_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 323.0
CSH2_k127_6429678_2 - - - - 0.0000000001875 64.0
CSH2_k127_6438172_0 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005783 273.0
CSH2_k127_6438172_1 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001537 239.0
CSH2_k127_6438172_2 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000147 169.0
CSH2_k127_6438172_3 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000006674 162.0
CSH2_k127_6440089_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 1e-223 705.0
CSH2_k127_6440089_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000007375 242.0
CSH2_k127_6440089_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000004935 183.0
CSH2_k127_6440089_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000001563 109.0
CSH2_k127_6453972_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 423.0
CSH2_k127_6453972_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 405.0
CSH2_k127_6453972_2 methyltransferase K04786 - - 0.000000000000000000000000000000000000633 144.0
CSH2_k127_6470310_0 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 304.0
CSH2_k127_6470310_1 PFAM response regulator receiver K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007146 261.0
CSH2_k127_6470310_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000001421 115.0
CSH2_k127_6470443_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002948 234.0
CSH2_k127_6470443_1 Phosphoesterase K07095 - - 0.00000000000000000000000000000000000000000000000000001433 192.0
CSH2_k127_6470443_2 PBP superfamily domain K02040 - - 0.00000004046 63.0
CSH2_k127_6492242_0 archaeal or bacterial-type flagellum-dependent cell motility K03408,K03414 GO:0001539,GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032991,GO:0036211,GO:0040011,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0097588,GO:0098561,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 387.0
CSH2_k127_6492242_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005717 241.0
CSH2_k127_6499561_0 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000001059 267.0
CSH2_k127_6523774_0 COGs COG1639 signal transduction protein - - - 0.00000000000000000000000000000000000000000000000000000000001515 221.0
CSH2_k127_6523774_1 NosL - - - 0.000000000000000000000000000000000000000000000001012 179.0
CSH2_k127_6523774_3 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000009633 151.0
CSH2_k127_6543703_0 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000005778 211.0
CSH2_k127_6543703_1 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000001215 206.0
CSH2_k127_6543703_2 membrane K09133 - - 0.00000000000000000000000000000000000000001271 158.0
CSH2_k127_6547108_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 389.0
CSH2_k127_6552830_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 365.0
CSH2_k127_6552830_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000001705 250.0
CSH2_k127_6552830_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000008834 217.0
CSH2_k127_6552830_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000009297 146.0
CSH2_k127_6554778_0 ABC-2 family transporter protein K01992,K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 419.0
CSH2_k127_6554778_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009423 282.0
CSH2_k127_6554778_2 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000001168 211.0
CSH2_k127_6569806_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 430.0
CSH2_k127_6569806_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000005672 90.0
CSH2_k127_6584412_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 351.0
CSH2_k127_6584412_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000004919 218.0
CSH2_k127_6604564_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 2.569e-230 724.0
CSH2_k127_6626865_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 526.0
CSH2_k127_6626865_1 Ecdysteroid kinase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 314.0
CSH2_k127_662765_0 sugar transferase K00996 - 2.7.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 391.0
CSH2_k127_662765_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 364.0
CSH2_k127_662765_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000002135 220.0
CSH2_k127_662765_3 Outer membrane lipoprotein - - - 0.00003359 47.0
CSH2_k127_6629223_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01665 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 417.0
CSH2_k127_6629223_1 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 316.0
CSH2_k127_6629223_2 carbon dioxide binding K04653 - - 0.000000000000000000000001654 105.0
CSH2_k127_6673839_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 283.0
CSH2_k127_6673839_1 DisA bacterial checkpoint controller nucleotide-binding - - - 0.000000000000000000000000000000000000000000004725 174.0
CSH2_k127_6675768_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 603.0
CSH2_k127_6675768_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 568.0
CSH2_k127_6675768_2 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000008892 177.0
CSH2_k127_6675768_3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000000001013 175.0
CSH2_k127_6675768_4 - - - - 0.00000000000000003141 89.0
CSH2_k127_6678997_0 Domain of unknown function (DUF4347) - - - 0.00000000000000000000000000000000000000000000000000000000000002678 233.0
CSH2_k127_6684831_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 3.887e-216 679.0
CSH2_k127_6684831_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 326.0
CSH2_k127_6700047_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 347.0
CSH2_k127_6700047_1 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0002309 48.0
CSH2_k127_6723918_0 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 531.0
CSH2_k127_6723918_1 Cobalamin synthesis G N-terminal K13541 - 2.1.1.131,3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 497.0
CSH2_k127_6723918_2 Biotin-protein ligase, N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000005344 237.0
CSH2_k127_6733441_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 412.0
CSH2_k127_6744104_0 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 359.0
CSH2_k127_6744104_1 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 323.0
CSH2_k127_6746870_0 phosphorelay signal transduction system K02584,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 421.0
CSH2_k127_6748417_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 426.0
CSH2_k127_6748417_1 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 355.0
CSH2_k127_6748417_2 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 291.0
CSH2_k127_6748417_3 PFAM Pilus assembly protein PilO K02664 - - 0.00000000000000133 85.0
CSH2_k127_6748417_4 Pilus assembly protein, PilP K02665 - - 0.00000000000147 75.0
CSH2_k127_6748417_5 PFAM Fimbrial assembly family protein K02663 - - 0.00000001309 63.0
CSH2_k127_6762_0 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 473.0
CSH2_k127_6762_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 296.0
CSH2_k127_6762_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000001745 255.0
CSH2_k127_6762_3 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000001549 146.0
CSH2_k127_685483_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003397 287.0
CSH2_k127_693185_0 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 296.0
CSH2_k127_693185_1 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001465 247.0
CSH2_k127_721199_0 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 310.0
CSH2_k127_747363_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 9.647e-242 767.0
CSH2_k127_747363_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000006869 243.0
CSH2_k127_769057_0 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 348.0
CSH2_k127_769057_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000006088 91.0
CSH2_k127_770327_0 Bacterial export proteins, family 1 K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000004379 227.0
CSH2_k127_770327_1 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000003647 185.0
CSH2_k127_770327_2 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000001373 180.0
CSH2_k127_770327_3 Role in flagellar biosynthesis K02420 - - 0.000000000000000000000000000000001141 132.0
CSH2_k127_797560_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 400.0
CSH2_k127_799931_0 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000002993 91.0
CSH2_k127_799931_1 Protein of unknown function (DUF3617) - - - 0.0000000000000000004925 93.0
CSH2_k127_799931_2 - - - - 0.00000000009534 65.0
CSH2_k127_804646_0 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 497.0
CSH2_k127_804646_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000002156 126.0
CSH2_k127_804646_2 phosphorelay sensor kinase activity K07708 - 2.7.13.3 0.0000002118 59.0
CSH2_k127_822270_0 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 338.0
CSH2_k127_822270_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 329.0
CSH2_k127_822270_2 pfam abc K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006037 275.0
CSH2_k127_822270_3 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000454 266.0
CSH2_k127_845185_0 Domain of unknown function (DUF4881) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009453 250.0
CSH2_k127_845185_1 - - - - 0.00000000000000000000000000000000000000004118 162.0
CSH2_k127_876353_0 PFAM Fimbrial assembly K02461 - - 0.00000000791 68.0
CSH2_k127_878551_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 402.0
CSH2_k127_878551_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 391.0
CSH2_k127_878551_2 PFAM glycosyl transferase, family 9 K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003046 276.0
CSH2_k127_878551_3 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000005958 195.0
CSH2_k127_878551_4 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000007699 191.0
CSH2_k127_898593_0 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000007382 213.0
CSH2_k127_898593_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000005953 66.0
CSH2_k127_916388_0 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000175 283.0
CSH2_k127_916388_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000001967 188.0
CSH2_k127_924162_0 GYD domain - - - 0.000000000000000000000000000000000000008487 146.0
CSH2_k127_924162_2 GYD domain - - - 0.0000000000000000000000000001387 119.0
CSH2_k127_924162_3 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000006001 75.0
CSH2_k127_924162_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000007658 61.0
CSH2_k127_924162_5 Cation efflux family K16264 - - 0.0000003975 53.0
CSH2_k127_942771_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 518.0
CSH2_k127_942771_1 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000003678 246.0
CSH2_k127_942771_2 response regulator, receiver - - - 0.000000000000000000000003199 109.0
CSH2_k127_950750_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.632e-250 786.0
CSH2_k127_950750_1 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 4.75e-234 735.0
CSH2_k127_950750_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 342.0
CSH2_k127_950750_3 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 323.0
CSH2_k127_950750_4 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001496 276.0
CSH2_k127_952573_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000001214 235.0
CSH2_k127_952573_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000001244 201.0
CSH2_k127_955197_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 388.0
CSH2_k127_955197_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001942 252.0
CSH2_k127_975014_0 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000000000008573 188.0
CSH2_k127_975014_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000001204 59.0
CSH2_k127_986837_0 Purine nucleoside phosphorylase involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 315.0
CSH2_k127_986837_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 292.0
CSH2_k127_986837_2 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000002458 157.0
CSH2_k127_996296_0 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 361.0
CSH2_k127_996296_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000009965 222.0
CSH2_k127_996296_2 Formyl transferase, C-terminal domain K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000008034 162.0