Overview

ID MAG00610
Name CSH2_bin.27
Sample SMP0014
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class EX4484-6
Order EX4484-6
Family EX4484-6
Genus JALOTP01
Species
Assembly information
Completeness (%) 68.61
Contamination (%) 1.02
GC content (%) 56.0
N50 (bp) 3,192
Genome size (bp) 1,691,399

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1343

Gene name Description KEGG GOs EC E-value Score Sequence
CSH2_k127_1041881_0 Protein of unknown function (DUF531) K09725 - - 0.0000000000000000000000002718 116.0
CSH2_k127_1041881_1 Kelch motif - - - 0.00000000000003591 80.0
CSH2_k127_1042109_0 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000001704 211.0
CSH2_k127_1042109_1 Belongs to the pirin family K06911 - - 0.000000000002879 74.0
CSH2_k127_1042109_2 Fe-S protein K18979 - 1.17.99.6 0.0009609 51.0
CSH2_k127_1062464_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000003068 68.0
CSH2_k127_109008_0 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 508.0
CSH2_k127_109008_1 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.000000000000000000000000000000000000005059 156.0
CSH2_k127_109008_2 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000002097 75.0
CSH2_k127_109008_3 - K02450 - - 0.000000000000451 79.0
CSH2_k127_109008_4 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.0003054 51.0
CSH2_k127_1106399_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000002265 236.0
CSH2_k127_1106399_1 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000001801 152.0
CSH2_k127_1106399_2 archaeal coiled-coil protein - - - 0.00007121 54.0
CSH2_k127_1115375_0 - - - - 0.000000000000000000000000000000000001253 142.0
CSH2_k127_1127363_0 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.00000006964 54.0
CSH2_k127_1127770_0 Subtilase family K17734 - - 0.000000000000000000000000189 117.0
CSH2_k127_1127770_1 - K00960 - 2.7.7.6 0.000000000000003805 79.0
CSH2_k127_1133358_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000007292 106.0
CSH2_k127_1169383_0 Heat shock 70 kDa protein K04043 - - 8.147e-235 736.0
CSH2_k127_1205059_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 415.0
CSH2_k127_1205059_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000001762 213.0
CSH2_k127_1239352_0 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000003509 87.0
CSH2_k127_1282225_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000001399 178.0
CSH2_k127_1282225_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000001548 181.0
CSH2_k127_1282225_2 protein conserved in archaea K09746 - - 0.0000000000000000000003217 107.0
CSH2_k127_1282225_3 - - - - 0.00000000001721 68.0
CSH2_k127_1282225_4 PFAM TPR repeat-containing protein - - - 0.00000000005731 75.0
CSH2_k127_1282225_5 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000539 43.0
CSH2_k127_1301918_0 TIGRFAM conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 313.0
CSH2_k127_1301918_1 myosin light chain kinase activity K12567 - 2.7.11.1 0.00000000000000000006297 106.0
CSH2_k127_1317420_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000001072 191.0
CSH2_k127_1317420_1 Phosphopantetheine adenylyltransferase K02201 - 2.7.7.3 0.000000000000000000000000001859 117.0
CSH2_k127_1317420_2 Beta-lactamase superfamily domain - - - 0.0000000000000000002503 92.0
CSH2_k127_1317420_3 PFAM Rhomboid family - - - 0.0000000000000002181 90.0
CSH2_k127_1317420_4 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.00000000000000881 77.0
CSH2_k127_1317420_5 Protein conserved in bacteria - - - 0.0000001243 65.0
CSH2_k127_1333472_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007857 224.0
CSH2_k127_1333472_1 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000003212 159.0
CSH2_k127_1333472_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000001019 160.0
CSH2_k127_1333472_3 PFAM DNA alkylation repair enzyme - - - 0.0000000003303 64.0
CSH2_k127_1364946_0 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.0003126 54.0
CSH2_k127_136749_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 364.0
CSH2_k127_136749_1 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001711 250.0
CSH2_k127_1371016_0 transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001603 290.0
CSH2_k127_1374261_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000001177 208.0
CSH2_k127_1374261_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000006775 197.0
CSH2_k127_1374261_2 endo-1,4-beta-xylanase activity K21636 - 1.1.98.6 0.00000188 61.0
CSH2_k127_1380348_0 Beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 400.0
CSH2_k127_1380348_1 PFAM Thiamin pyrophosphokinase catalytic K00949 - 2.7.6.2 0.000000000000000000000000000006907 126.0
CSH2_k127_1380348_2 chlorophyll binding - - - 0.0000000000001269 87.0
CSH2_k127_1380348_3 Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family K10352,K17751,K18669 GO:0000003,GO:0000146,GO:0000166,GO:0000278,GO:0000281,GO:0000902,GO:0000904,GO:0000910,GO:0001568,GO:0001654,GO:0001655,GO:0001667,GO:0001700,GO:0001701,GO:0001725,GO:0001736,GO:0001738,GO:0001745,GO:0001764,GO:0001778,GO:0001894,GO:0001944,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0002791,GO:0002793,GO:0003002,GO:0003006,GO:0003008,GO:0003012,GO:0003205,GO:0003279,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003774,GO:0003779,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005826,GO:0005829,GO:0005844,GO:0005856,GO:0005886,GO:0005903,GO:0005911,GO:0005938,GO:0006810,GO:0006887,GO:0006928,GO:0006929,GO:0006930,GO:0006935,GO:0006936,GO:0006950,GO:0006996,GO:0007009,GO:0007010,GO:0007015,GO:0007049,GO:0007097,GO:0007155,GO:0007163,GO:0007164,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007386,GO:0007389,GO:0007391,GO:0007392,GO:0007395,GO:0007399,GO:0007405,GO:0007409,GO:0007411,GO:0007417,GO:0007420,GO:0007423,GO:0007424,GO:0007431,GO:0007435,GO:0007442,GO:0007443,GO:0007444,GO:0007455,GO:0007472,GO:0007476,GO:0007494,GO:0007496,GO:0007507,GO:0007512,GO:0007552,GO:0007560,GO:0008092,GO:0008104,GO:0008144,GO:0008150,GO:0008258,GO:0008283,GO:0008356,GO:0008360,GO:0008544,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009798,GO:0009886,GO:0009887,GO:0009888,GO:0009913,GO:0009952,GO:0009987,GO:0010256,GO:0010631,GO:0010830,GO:0010927,GO:0014706,GO:0015629,GO:0016020,GO:0016043,GO:0016192,GO:0016318,GO:0016331,GO:0016459,GO:0016460,GO:0016461,GO:0016462,GO:0016477,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017022,GO:0017076,GO:0017111,GO:0017145,GO:0019953,GO:0021537,GO:0021549,GO:0021591,GO:0021592,GO:0021670,GO:0021678,GO:0021680,GO:0021695,GO:0022008,GO:0022037,GO:0022402,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022610,GO:0022612,GO:0030010,GO:0030016,GO:0030017,GO:0030018,GO:0030027,GO:0030029,GO:0030030,GO:0030031,GO:0030036,GO:0030048,GO:0030054,GO:0030154,GO:0030182,GO:0030239,GO:0030424,GO:0030425,GO:0030426,GO:0030427,GO:0030496,GO:0030554,GO:0030707,GO:0030855,GO:0030863,GO:0030864,GO:0030898,GO:0030900,GO:0030902,GO:0031032,GO:0031033,GO:0031034,GO:0031036,GO:0031038,GO:0031175,GO:0031252,GO:0031674,GO:0032027,GO:0032153,GO:0032154,GO:0032155,GO:0032432,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032940,GO:0032982,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033267,GO:0034613,GO:0034622,GO:0035017,GO:0035026,GO:0035051,GO:0035107,GO:0035114,GO:0035120,GO:0035150,GO:0035151,GO:0035152,GO:0035159,GO:0035214,GO:0035220,GO:0035239,GO:0035272,GO:0035277,GO:0035295,GO:0035315,GO:0035316,GO:0035317,GO:0035613,GO:0035639,GO:0035904,GO:0036094,GO:0036445,GO:0036477,GO:0040011,GO:0042060,GO:0042067,GO:0042221,GO:0042330,GO:0042335,GO:0042592,GO:0042623,GO:0042641,GO:0042692,GO:0042802,GO:0042995,GO:0043005,GO:0043009,GO:0043010,GO:0043025,GO:0043167,GO:0043168,GO:0043197,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043531,GO:0043933,GO:0044085,GO:0044291,GO:0044297,GO:0044309,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044877,GO:0045165,GO:0045177,GO:0045179,GO:0045185,GO:0045196,GO:0045200,GO:0045202,GO:0045214,GO:0045595,GO:0046663,GO:0046664,GO:0046903,GO:0046907,GO:0048027,GO:0048103,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048546,GO:0048563,GO:0048565,GO:0048569,GO:0048592,GO:0048598,GO:0048609,GO:0048619,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048738,GO:0048749,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0048871,GO:0050708,GO:0050714,GO:0050789,GO:0050793,GO:0050794,GO:0050808,GO:0050877,GO:0050885,GO:0050896,GO:0050905,GO:0051015,GO:0051017,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051128,GO:0051146,GO:0051147,GO:0051153,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051235,GO:0051259,GO:0051301,GO:0051640,GO:0051641,GO:0051647,GO:0051649,GO:0051651,GO:0051656,GO:0051674,GO:0051704,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055012,GO:0055013,GO:0055015,GO:0055057,GO:0055059,GO:0055123,GO:0060041,GO:0060142,GO:0060249,GO:0060289,GO:0060322,GO:0060429,GO:0060537,GO:0060541,GO:0060562,GO:0060571,GO:0060840,GO:0060972,GO:0060976,GO:0061024,GO:0061061,GO:0061326,GO:0061333,GO:0061351,GO:0061525,GO:0061564,GO:0061572,GO:0061640,GO:0065003,GO:0065007,GO:0065008,GO:0070201,GO:0070650,GO:0070727,GO:0070925,GO:0070938,GO:0070986,GO:0071214,GO:0071260,GO:0071496,GO:0071840,GO:0071944,GO:0072001,GO:0072002,GO:0072089,GO:0072358,GO:0072359,GO:0090066,GO:0090087,GO:0090130,GO:0090132,GO:0090596,GO:0097159,GO:0097367,GO:0097435,GO:0097447,GO:0097458,GO:0097485,GO:0097513,GO:0097517,GO:0098590,GO:0098722,GO:0098794,GO:0098862,GO:0098885,GO:0099010,GO:0099080,GO:0099081,GO:0099512,GO:0099563,GO:0099568,GO:0099738,GO:0104004,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:1901265,GO:1901363,GO:1901739,GO:1903047,GO:1903530,GO:1903532,GO:1904951,GO:1990904 2.7.12.1 0.000002447 60.0
CSH2_k127_1380348_4 PFAM F5 8 type C domain K01183 - 3.2.1.14 0.0005762 55.0
CSH2_k127_138235_0 amine dehydrogenase activity K20276 - - 0.00000000000000000000000000000000000000009704 161.0
CSH2_k127_138235_1 exo-alpha-(2->6)-sialidase activity K20276 - - 0.000000000000000000000186 105.0
CSH2_k127_1385943_0 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008307 373.0
CSH2_k127_1385943_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 326.0
CSH2_k127_1385943_2 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000003136 145.0
CSH2_k127_1389259_0 DNA polymerase type-B family K02319 - 2.7.7.7 1.167e-198 640.0
CSH2_k127_1426308_0 PFAM Peptidase M18, aminopeptidase I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 396.0
CSH2_k127_1426308_1 Has ATPase and non-specific DNA-binding activities K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003228 285.0
CSH2_k127_1426308_2 KaiC K08482 - - 0.0000004459 59.0
CSH2_k127_1434736_0 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 383.0
CSH2_k127_1434736_1 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.0000000000000000000000000000000000000000000000001588 186.0
CSH2_k127_1434736_2 dehydrogenase complex catalyzes the overall conversion of - - - 0.000000000000000000000000000000000000000009214 164.0
CSH2_k127_1434736_3 TIGRFAM segregation and condensation protein B K06024 - - 0.0000000000000000000000000003405 123.0
CSH2_k127_1434736_4 membrane transporter protein K07090 - - 0.000000000000000009479 93.0
CSH2_k127_1434736_5 Histidine kinase-like ATPases - - - 0.0000000000003557 78.0
CSH2_k127_1434736_6 chromosome segregation and condensation protein ScpA K05896 - - 0.00000007842 62.0
CSH2_k127_1442884_0 PFAM SMP-30 Gluconolaconase K20952 - - 0.0003357 53.0
CSH2_k127_1453942_0 Peptidase family M50 - - - 0.0000000000000000000000000003749 123.0
CSH2_k127_1453942_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000001281 66.0
CSH2_k127_1453942_2 Tetratricopeptide repeat - - - 0.00000000657 64.0
CSH2_k127_1453942_3 - - - - 0.0001799 49.0
CSH2_k127_1462152_0 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000000000002407 177.0
CSH2_k127_1462152_1 FG-GAP repeat - - - 0.000000001076 72.0
CSH2_k127_1487023_0 COG NOG14118 non supervised orthologous group - - - 0.00003087 48.0
CSH2_k127_1487023_1 DNA polymerase III K02342 - 2.7.7.7 0.0004649 49.0
CSH2_k127_1490322_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 312.0
CSH2_k127_1490322_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 299.0
CSH2_k127_1490322_2 Antibiotic biosynthesis monooxygenase - - - 0.00000003371 59.0
CSH2_k127_1490396_0 Bacterial pre-peptidase C-terminal domain - - - 0.00009971 50.0
CSH2_k127_1502983_0 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001051 250.0
CSH2_k127_1513910_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000001045 105.0
CSH2_k127_1572045_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000005991 84.0
CSH2_k127_1572045_2 Dystroglycan-type cadherin-like domains. - - - 0.000000000007575 79.0
CSH2_k127_1572045_3 PFAM HAD-superfamily hydrolase subfamily IB - - - 0.0009458 48.0
CSH2_k127_1576220_0 - - - - 0.0000000000000000000000000000000717 133.0
CSH2_k127_1576220_1 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.0000000000000000006484 95.0
CSH2_k127_1576220_2 Protein tyrosine kinase - - - 0.000001009 60.0
CSH2_k127_1579289_0 - - - - 0.00000000000000000000002107 115.0
CSH2_k127_1579595_0 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000001191 243.0
CSH2_k127_1579595_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001718 158.0
CSH2_k127_1585728_0 Succinyl-CoA ligase like flavodoxin domain K18593 - - 0.00000000000000000000000000000000000000000000000002064 184.0
CSH2_k127_1585728_1 DRTGG domain protein K06873 - - 0.0000000000000000000000000002924 126.0
CSH2_k127_1585728_2 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000004305 94.0
CSH2_k127_1590119_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000002684 192.0
CSH2_k127_1590119_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000009378 161.0
CSH2_k127_1590119_2 Diacylglycerol kinase catalytic domain K07029 GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 0.00000000000000000000000004217 119.0
CSH2_k127_1619714_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000004292 75.0
CSH2_k127_1619714_1 biotin apo-protein ligase K01942 GO:0003674,GO:0003824,GO:0004077,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009305,GO:0009987,GO:0010467,GO:0016874,GO:0016879,GO:0018271,GO:0019538,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:0071734,GO:0140096,GO:1901564 6.3.4.10,6.3.4.11,6.3.4.15,6.3.4.9 0.000541 51.0
CSH2_k127_1621966_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000001869 96.0
CSH2_k127_1650511_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 329.0
CSH2_k127_1657523_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000001092 120.0
CSH2_k127_1701773_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 482.0
CSH2_k127_1701773_1 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000006098 171.0
CSH2_k127_1712745_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003507 249.0
CSH2_k127_1712745_1 Peptidyl-prolyl cis-trans K01802,K03775 - 5.2.1.8 0.00000000000000000000000000000000000000384 157.0
CSH2_k127_1721297_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 434.0
CSH2_k127_1721297_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 305.0
CSH2_k127_1728605_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 294.0
CSH2_k127_1728605_1 PFAM polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000006487 201.0
CSH2_k127_1728605_2 Glycosyltransferase Family 4 K14949 - 2.7.11.1 0.0000000000000000000000000000005088 136.0
CSH2_k127_1728605_3 Glycosyl transferases group 1 - - - 0.00000000000000000006549 97.0
CSH2_k127_1735109_0 DnaJ domain protein K05516 - - 0.00000004592 62.0
CSH2_k127_1736958_0 MGS-like domain K00602,K01492 - 2.1.2.2,2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 377.0
CSH2_k127_1740776_0 PFAM short-chain dehydrogenase reductase SDR K15314 - - 1.086e-250 820.0
CSH2_k127_1748773_0 Belongs to the ompA family K20276 - - 0.00000004396 66.0
CSH2_k127_1755262_0 Pfam:KaiC - - - 0.000000000000000000000000000000003154 138.0
CSH2_k127_1755262_1 membrane - - - 0.000000000007734 75.0
CSH2_k127_1755262_2 Muskelin N-terminus - GO:0000003,GO:0001556,GO:0001726,GO:0001952,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005938,GO:0006996,GO:0007010,GO:0007154,GO:0007155,GO:0007160,GO:0007165,GO:0007276,GO:0007281,GO:0007292,GO:0008150,GO:0008360,GO:0009987,GO:0009994,GO:0010810,GO:0016043,GO:0019953,GO:0021700,GO:0022412,GO:0022414,GO:0022603,GO:0022604,GO:0022610,GO:0023052,GO:0030029,GO:0030036,GO:0030154,GO:0030155,GO:0031252,GO:0031532,GO:0031589,GO:0032501,GO:0032502,GO:0032504,GO:0042802,GO:0042995,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0048468,GO:0048469,GO:0048477,GO:0048599,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051704,GO:0051716,GO:0065007,GO:0065008,GO:0071695,GO:0071840,GO:0071944,GO:0099568,GO:0120025 - 0.0000001056 66.0
CSH2_k127_1766659_0 PFAM amidohydrolase K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 329.0
CSH2_k127_1766659_1 ATP binding protein K06927 - 6.3.1.14 0.00000009584 54.0
CSH2_k127_1767879_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001424 257.0
CSH2_k127_1767879_1 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001639 205.0
CSH2_k127_1767879_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000257 195.0
CSH2_k127_1767879_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000104 158.0
CSH2_k127_1768352_0 KH domain K07041 - - 1.151e-235 741.0
CSH2_k127_1768352_1 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000002225 158.0
CSH2_k127_1776008_0 SMART Tetratricopeptide - - - 0.0000002715 60.0
CSH2_k127_1776008_1 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00005974 55.0
CSH2_k127_1783214_0 Protein of unknown function, DUF255 K06888 - - 3.629e-198 638.0
CSH2_k127_1783214_1 Glycosyl transferase family group 2 - - - 0.0005016 42.0
CSH2_k127_178348_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 420.0
CSH2_k127_178348_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001438 276.0
CSH2_k127_178348_2 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000003339 209.0
CSH2_k127_178348_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000322 69.0
CSH2_k127_178348_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000008131 66.0
CSH2_k127_178348_5 archaeal Zn-finger protein - - - 0.00002591 50.0
CSH2_k127_1786051_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000157 265.0
CSH2_k127_1786051_1 transcriptional regulator - - - 0.00000000000000000000000000000000007622 149.0
CSH2_k127_179381_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 342.0
CSH2_k127_179381_1 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.0000000000000000000000000000000000000000000609 171.0
CSH2_k127_1828803_0 Belongs to the V-ATPase 116 kDa subunit family K02123 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000009022 123.0
CSH2_k127_1831465_0 FtsX-like permease family K02004 - - 0.000000000000000002065 100.0
CSH2_k127_1831465_1 gluconolactonase activity K01053,K01179,K07214,K12287 - 3.1.1.17,3.2.1.4 0.0000001478 62.0
CSH2_k127_1848557_0 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000676 246.0
CSH2_k127_188219_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K18016 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 308.0
CSH2_k127_188219_1 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001411 275.0
CSH2_k127_1891777_0 3-Beta hydroxysteroid dehydrogenase isomerase K21271,K22320 - 1.1.1.394,1.1.1.412 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 363.0
CSH2_k127_1891777_1 Major facilitator superfamily - - - 0.0000000000000000000000000000109 123.0
CSH2_k127_1891777_2 PFAM AMP-dependent synthetase and ligase K22319 - 6.1.3.1 0.0000000000000000006259 88.0
CSH2_k127_1891939_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 511.0
CSH2_k127_1891939_1 Protein of unknown function (DUF357) K09728 - - 0.00000000000000003181 81.0
CSH2_k127_1915467_0 Pyruvate phosphate dikinase, PEP pyruvate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000921 299.0
CSH2_k127_1915467_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000004264 234.0
CSH2_k127_2017634_0 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000001479 104.0
CSH2_k127_2018284_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000001277 211.0
CSH2_k127_2024756_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001468 275.0
CSH2_k127_2028776_0 domain, Protein - - - 0.00000000000000000000000000001795 136.0
CSH2_k127_2067450_0 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000005021 142.0
CSH2_k127_2067450_1 Peptidase family C25 - - - 0.000000000000000002562 99.0
CSH2_k127_2067450_2 4-amino-4-deoxy-L-arabinose transferase activity K00728 - 2.4.1.109 0.0000001697 64.0
CSH2_k127_2087058_0 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000002761 146.0
CSH2_k127_2087058_1 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000001516 108.0
CSH2_k127_2087058_2 - - - - 0.0000000000000000000000006123 110.0
CSH2_k127_2099824_0 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 336.0
CSH2_k127_2099824_1 PAS fold - - - 0.00000000000000000000000000000000000000000001553 177.0
CSH2_k127_2099824_2 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000001856 61.0
CSH2_k127_2107086_0 DEAD_2 K07464,K10844 - 3.1.12.1,3.6.4.12 0.0000000000009006 81.0
CSH2_k127_2165840_0 hmm pf01734 K07001 - - 0.00000000000000000000000000000000000000004071 163.0
CSH2_k127_2175030_0 COG0191 Fructose tagatose bisphosphate aldolase K01624,K08302 - 4.1.2.13,4.1.2.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 415.0
CSH2_k127_2175030_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003141 280.0
CSH2_k127_2175030_2 PFAM B3 4 domain - - - 0.000000000000000000000000000000000000000000000001292 181.0
CSH2_k127_2175030_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000001039 87.0
CSH2_k127_2175030_4 protein contain chitin-binding domain type 3 - - - 0.000000648 58.0
CSH2_k127_2204873_0 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 372.0
CSH2_k127_2204873_1 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000004621 172.0
CSH2_k127_2204873_2 fibrinogen binding K06476,K06487,K06584 GO:0001775,GO:0002576,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005912,GO:0005924,GO:0005925,GO:0006810,GO:0006887,GO:0006950,GO:0007155,GO:0007160,GO:0007596,GO:0007599,GO:0008150,GO:0009611,GO:0009897,GO:0009986,GO:0009987,GO:0012505,GO:0012506,GO:0016020,GO:0016043,GO:0016192,GO:0022610,GO:0030054,GO:0030055,GO:0030141,GO:0030168,GO:0030198,GO:0030334,GO:0030335,GO:0030659,GO:0030667,GO:0031090,GO:0031091,GO:0031092,GO:0031410,GO:0031589,GO:0031982,GO:0032501,GO:0032879,GO:0032940,GO:0034109,GO:0040012,GO:0040017,GO:0042060,GO:0042802,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045595,GO:0045637,GO:0045652,GO:0046903,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0050817,GO:0050840,GO:0050878,GO:0050896,GO:0051179,GO:0051234,GO:0051239,GO:0051270,GO:0051272,GO:0065007,GO:0065008,GO:0070051,GO:0070062,GO:0070161,GO:0070527,GO:0071840,GO:0071944,GO:0097708,GO:0098552,GO:0098588,GO:0098609,GO:0098805,GO:0099503,GO:1903561,GO:1903706,GO:2000026,GO:2000145,GO:2000147 - 0.00000000001595 78.0
CSH2_k127_2223322_0 COG1522 Transcriptional regulators - - - 0.000000000000000005764 85.0
CSH2_k127_2223322_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000002012 89.0
CSH2_k127_2223322_2 Histidine kinase - - - 0.000000000000004151 85.0
CSH2_k127_2233969_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008112 458.0
CSH2_k127_2233969_1 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.00000000001954 67.0
CSH2_k127_2233969_2 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000003026 61.0
CSH2_k127_2245351_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 619.0
CSH2_k127_2245351_1 ribosomal protein L15 K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001482 91.0
CSH2_k127_2248890_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000006398 223.0
CSH2_k127_2248890_1 Winged helix-turn-helix DNA-binding - - - 0.00006841 50.0
CSH2_k127_2273233_0 PFAM Desulfoferrodoxin, ferrous iron-binding region K05919 - 1.15.1.2 0.00000000000000000000000000000000004492 138.0
CSH2_k127_2273233_1 PFAM peptidase M28 - - - 0.000000000000000002885 98.0
CSH2_k127_2274631_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 556.0
CSH2_k127_2274631_1 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000000000000002802 240.0
CSH2_k127_2274631_2 Helix-turn-helix diphteria tox regulatory element - - - 0.000000000000000000000000000000771 126.0
CSH2_k127_2274631_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone - - - 0.0000000000000000005084 91.0
CSH2_k127_2274631_4 antibiotic catabolic process K01174,K02238,K08651,K13277,K20276,K20486 - 3.1.31.1,3.4.21.66 0.00000001241 69.0
CSH2_k127_2297819_0 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000001434 214.0
CSH2_k127_2297819_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000009356 206.0
CSH2_k127_2299241_0 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000001358 195.0
CSH2_k127_2299241_1 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.00000000000000000000000000000001292 134.0
CSH2_k127_2299241_2 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.000000000000001038 89.0
CSH2_k127_2303895_0 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 331.0
CSH2_k127_2303895_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000007719 95.0
CSH2_k127_232271_0 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 452.0
CSH2_k127_232271_1 phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000002725 179.0
CSH2_k127_232271_2 Methyltransferase - - - 0.000000000000000000000000006502 119.0
CSH2_k127_232271_3 Sulfite exporter TauE/SafE K07090 - - 0.000000001183 64.0
CSH2_k127_232271_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000003517 60.0
CSH2_k127_232271_5 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase - - - 0.0002987 53.0
CSH2_k127_2343340_0 TIGRFAM RHS repeat-associated core domain - - - 0.000000000000001236 91.0
CSH2_k127_2343340_1 Predicted membrane protein (DUF2085) - - - 0.000000003583 63.0
CSH2_k127_2357327_0 hyaluronan metabolic process - GO:0002526,GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0008150,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034097,GO:0034774,GO:0042221,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.00000000000000000000000000000000000000000000000000000001129 218.0
CSH2_k127_2386877_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain - - - 1.814e-216 679.0
CSH2_k127_2390471_0 tetratricopeptide repeat - - - 0.0000000000000002246 82.0
CSH2_k127_2398867_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 380.0
CSH2_k127_2403691_0 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.00000000000000964 88.0
CSH2_k127_2403743_0 DnaJ molecular chaperone homology domain - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0008150,GO:0009314,GO:0009416,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009628,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050896 - 0.0008308 50.0
CSH2_k127_2413119_0 TIGRFAM MIP family channel K02440,K06188 - - 0.00000000000000000000000001655 111.0
CSH2_k127_2413119_1 repeat protein - - - 0.000005128 59.0
CSH2_k127_2418035_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000003655 141.0
CSH2_k127_2418035_1 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000001923 137.0
CSH2_k127_2418208_0 - - - - 0.00002735 57.0
CSH2_k127_2448956_0 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000001658 192.0
CSH2_k127_2448956_1 amine dehydrogenase activity - - - 0.0000002301 61.0
CSH2_k127_245654_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000001267 237.0
CSH2_k127_245654_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000009929 197.0
CSH2_k127_245654_2 HELICc2 K07464,K10844 - 3.1.12.1,3.6.4.12 0.0000000000000000001671 92.0
CSH2_k127_2479867_0 Belongs to the peptidase S8 family - - - 0.00000000000005696 87.0
CSH2_k127_2479867_1 Domain of unknown function DUF302 - - - 0.00000000000007144 72.0
CSH2_k127_2479867_2 metallopeptidase activity K01126,K01181 - 3.1.4.46,3.2.1.8 0.00000000001073 79.0
CSH2_k127_2481964_0 Psort location Cytoplasmic, score K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 325.0
CSH2_k127_2481964_1 Phospholipase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000007049 254.0
CSH2_k127_2481964_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.000000000000000002139 87.0
CSH2_k127_2481964_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000133 72.0
CSH2_k127_2487021_0 PFAM Ferritin, Dps family protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000002796 244.0
CSH2_k127_2487021_1 ABC transporter K06158 - - 0.0001351 46.0
CSH2_k127_2493674_0 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000002812 229.0
CSH2_k127_2493674_1 Protein of unknown function (DUF402) K07586 - - 0.000000000000000000000003256 107.0
CSH2_k127_2501274_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 316.0
CSH2_k127_2501274_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000004252 68.0
CSH2_k127_2501274_2 Protein of unknown function (DUF1294) - - - 0.00000004229 63.0
CSH2_k127_2501951_0 solute binding protein K02035 - - 0.000004637 60.0
CSH2_k127_2519620_0 - - - - 0.0000000000001136 82.0
CSH2_k127_2519620_1 HAD-hyrolase-like K07025 - - 0.0000000000003732 79.0
CSH2_k127_2519620_2 Pfam TM2 domain - - - 0.0000000000004666 72.0
CSH2_k127_2521166_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000006871 267.0
CSH2_k127_2521166_1 PAP2 superfamily - - - 0.00000000000000000000000000000002077 138.0
CSH2_k127_2523409_0 CARDB - - - 0.000004002 59.0
CSH2_k127_2534743_0 ATPase activity K01990,K19340 - - 0.0000000000000000000000000001302 119.0
CSH2_k127_2534743_1 ABC-2 family transporter protein K01992 - - 0.0000000000004767 79.0
CSH2_k127_2534743_2 COG2002 Regulators of stationary sporulation gene expression - - - 0.000000146 55.0
CSH2_k127_2540354_0 Fibronectin type III domain - - - 0.00000000000000000000000000000000000000000000000000001945 212.0
CSH2_k127_2546485_0 N-6 DNA Methylase K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.000000000000000000000000003023 123.0
CSH2_k127_2550803_0 Putative diphthamide synthesis protein K07561 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016765,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0048037,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0051536,GO:0051539,GO:0051540,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.5.1.108 0.00000000000000000000000000000000000000000000000000007391 200.0
CSH2_k127_2550803_1 FMN binding - - - 0.0000000000000000009169 92.0
CSH2_k127_2550803_2 - - - - 0.000000000003714 67.0
CSH2_k127_2550803_3 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00009981 49.0
CSH2_k127_2554413_0 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 303.0
CSH2_k127_2554413_1 Helix-turn-helix XRE-family like proteins K07728 - - 0.000000000000000000000000000000000000000000000002087 185.0
CSH2_k127_2580524_0 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 406.0
CSH2_k127_2580524_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000003631 173.0
CSH2_k127_2580524_2 PFAM CBS domain containing protein - - - 0.000005803 58.0
CSH2_k127_2593931_0 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000001055 100.0
CSH2_k127_2593931_1 binds to the 23S rRNA K02922 - - 0.00000000000000162 76.0
CSH2_k127_2593931_2 Cadherin repeats. - - - 0.000001253 62.0
CSH2_k127_2593931_3 Peptidase family C25 - - - 0.000003789 60.0
CSH2_k127_2608631_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000001302 81.0
CSH2_k127_2620886_0 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000154 247.0
CSH2_k127_2620886_1 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.0000000000001418 72.0
CSH2_k127_2627397_0 Peptidase S8 S53, subtilisin kexin sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 339.0
CSH2_k127_26287_0 Tetratricopeptide repeats - - - 0.000000000000000000021 106.0
CSH2_k127_26287_1 Protein of unknown function (DUF835) - - - 0.0002447 49.0
CSH2_k127_2629425_0 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000007724 215.0
CSH2_k127_2629425_1 PFAM Silent information regulator protein Sir2 K12410 - - 0.00000000000000000000000000000000000000000000000000000000005756 213.0
CSH2_k127_2629425_2 PFAM GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000002792 179.0
CSH2_k127_2629425_3 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000002069 147.0
CSH2_k127_2629425_4 Flavin reductase like domain - - - 0.00000000000000000000000006113 109.0
CSH2_k127_2629425_5 Belongs to the UPF0145 family - - - 0.000000000000002537 82.0
CSH2_k127_2629425_6 COG1404 Subtilisin-like serine proteases K13276 - - 0.000000122 59.0
CSH2_k127_2630874_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000002109 123.0
CSH2_k127_2638859_0 Archaeal Type IV pilin, N-terminal - - - 0.00000000000000000006677 103.0
CSH2_k127_2638859_1 ASPIC and UnbV - - - 0.0000000009068 67.0
CSH2_k127_2640510_0 Pro-kumamolisin, activation domain - - - 0.00000000005696 76.0
CSH2_k127_2641967_0 Pheromone shutdown protein - - - 0.00000000000000000000005466 108.0
CSH2_k127_2641967_1 DnaJ C terminal domain K05516 - - 0.0000006716 54.0
CSH2_k127_265035_0 Radical SAM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 298.0
CSH2_k127_265035_1 Major facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000001614 185.0
CSH2_k127_2653142_0 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.0000000000000000000000000000000000000000000000000000000001151 213.0
CSH2_k127_2657976_0 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000002984 149.0
CSH2_k127_2657976_1 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.000002617 53.0
CSH2_k127_2672678_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000005686 261.0
CSH2_k127_2672678_1 cluster protein-associated redox disulfide domain protein - - - 0.000000000000000000002412 96.0
CSH2_k127_2702955_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.642e-262 826.0
CSH2_k127_2702955_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000001863 92.0
CSH2_k127_2732251_0 Phosphate uptake regulator, PhoU - - - 0.00000000000000000000000000000000000000000000000000003468 201.0
CSH2_k127_2732251_1 Transglutaminase-like superfamily - - - 0.00000000001301 76.0
CSH2_k127_2732251_2 Oxidoreductase - - - 0.000001513 55.0
CSH2_k127_2737188_0 chitin catabolic process K01183 - 3.2.1.14 0.00000156 61.0
CSH2_k127_2746262_0 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000001395 78.0
CSH2_k127_2746262_1 PKD domain K09607,K19668 - 3.2.1.91 0.0000000008555 69.0
CSH2_k127_2778351_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000803 117.0
CSH2_k127_279713_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 318.0
CSH2_k127_279713_1 Lamin Tail Domain - - - 0.000006779 59.0
CSH2_k127_2801883_0 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.0000000000000000000000000000000000000003046 165.0
CSH2_k127_2801883_1 Belongs to the UPF0292 family - - - 0.00000000002873 72.0
CSH2_k127_2801883_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0004353 44.0
CSH2_k127_2801883_3 Pfam:KaiC K08482 - - 0.0006898 50.0
CSH2_k127_2813662_0 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.000000000000004326 83.0
CSH2_k127_2813662_1 - K16925 - - 0.00000000000003628 81.0
CSH2_k127_2813671_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 312.0
CSH2_k127_2813671_1 PFAM malic K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000001015 173.0
CSH2_k127_2820720_0 phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000005684 151.0
CSH2_k127_2858647_0 von Willebrand factor (vWF) type A domain - - - 0.000001093 61.0
CSH2_k127_2875831_0 Uncharacterised ACR (DUF711) K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 297.0
CSH2_k127_2875831_1 Thioredoxin-like K03671 - - 0.0000000000000000000009341 99.0
CSH2_k127_2875831_2 integral membrane protein K07027 - - 0.000000000000000829 89.0
CSH2_k127_2875831_3 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000001517 79.0
CSH2_k127_2875831_4 OPT oligopeptide transporter protein - - - 0.00001403 53.0
CSH2_k127_2875985_0 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000001254 89.0
CSH2_k127_2877440_0 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000006191 158.0
CSH2_k127_2877440_1 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000002848 87.0
CSH2_k127_2877440_2 ABC-2 family transporter protein K01992 - - 0.00008456 46.0
CSH2_k127_2883710_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 394.0
CSH2_k127_2883710_1 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002593 271.0
CSH2_k127_2883710_2 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005905 263.0
CSH2_k127_2883710_3 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000002892 79.0
CSH2_k127_2883710_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000006558 49.0
CSH2_k127_2894578_0 GvpD gas vesicle protein - - - 0.00000000000000000000000000000000000000000000000000006376 195.0
CSH2_k127_2894578_1 Phosphorylase superfamily K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000009478 167.0
CSH2_k127_2894578_2 protein conserved in archaea - - - 0.000000000166 76.0
CSH2_k127_2894578_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000001612 66.0
CSH2_k127_2897120_0 thiamine transport K02063 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682 - 0.000000000000000000000000000000000000000000000000000000000002683 224.0
CSH2_k127_2897120_1 TOBE domain K11084 - - 0.0000000000000000000000000000000000000007075 154.0
CSH2_k127_290100_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 363.0
CSH2_k127_290100_1 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001507 235.0
CSH2_k127_290100_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000005763 194.0
CSH2_k127_290100_3 - - - - 0.00000000000000000000000000000000004868 148.0
CSH2_k127_2911682_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465,K01466 - 3.5.2.3,3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 298.0
CSH2_k127_2911682_1 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001543 267.0
CSH2_k127_2911682_2 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000000000000000000003135 225.0
CSH2_k127_2911682_3 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000001224 131.0
CSH2_k127_2919799_0 PFAM Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 287.0
CSH2_k127_2919799_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000205 158.0
CSH2_k127_2919799_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000001181 166.0
CSH2_k127_2919799_3 protein conserved in archaea - - - 0.0000000001696 69.0
CSH2_k127_2919801_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 394.0
CSH2_k127_2928117_0 alginic acid biosynthetic process - - - 0.000000000000000000000001088 121.0
CSH2_k127_2928117_1 Pfam:DUF552 K09152 - - 0.0000000001766 65.0
CSH2_k127_2931364_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1130.0
CSH2_k127_2931364_1 Catalyzes the interconversion of ornithine to glutamate semialdehyde K00819 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 500.0
CSH2_k127_2931364_2 Periplasmic copper-binding protein (NosD) - - - 0.00000000097 69.0
CSH2_k127_2932932_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004674 268.0
CSH2_k127_2932932_1 Helix-turn-helix domain - - - 0.0005298 45.0
CSH2_k127_2963704_0 C-terminal region of MMR_HSR1 domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 394.0
CSH2_k127_2963704_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000001309 62.0
CSH2_k127_2968509_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 327.0
CSH2_k127_2968509_1 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000001096 157.0
CSH2_k127_2968509_2 SnoaL-like domain - - - 0.00000000000008456 72.0
CSH2_k127_2974031_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 305.0
CSH2_k127_2974031_1 Belongs to the peptidase S8 family - - - 0.000001211 56.0
CSH2_k127_2988023_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 6.844e-218 708.0
CSH2_k127_2988023_1 Glycoside hydrolase family 28 - - - 0.000004234 58.0
CSH2_k127_2988478_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 409.0
CSH2_k127_2988478_1 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 0.0000000000000000000000000000000000000006752 162.0
CSH2_k127_3002397_0 TonB-dependent receptor - - - 0.00007899 57.0
CSH2_k127_3008582_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 308.0
CSH2_k127_3008582_1 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.000000004754 62.0
CSH2_k127_3021347_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 326.0
CSH2_k127_3021347_1 protein conserved in archaea - - - 0.00000000001643 72.0
CSH2_k127_3025454_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000001026 149.0
CSH2_k127_3030604_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 559.0
CSH2_k127_3030604_1 HELICc2 K03722,K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000006084 259.0
CSH2_k127_3030604_2 transferase activity, transferring glycosyl groups - - - 0.00007461 51.0
CSH2_k127_3041126_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 322.0
CSH2_k127_3041126_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000007307 198.0
CSH2_k127_3041126_2 hydrolase K07025 - - 0.00000000001211 73.0
CSH2_k127_3041738_0 Uncharacterised protein family (UPF0147) K09721 - - 0.00000005577 54.0
CSH2_k127_3041738_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0007416 53.0
CSH2_k127_3061785_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 290.0
CSH2_k127_3061785_1 Fibronectin type III domain protein - - - 0.00000000000000000000000000000000000000000000000000000001254 222.0
CSH2_k127_3068446_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000009533 194.0
CSH2_k127_3068446_1 hemolysin III K11068 - - 0.0000000000000000000000000000000000000000004279 161.0
CSH2_k127_3068446_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000642 141.0
CSH2_k127_3112114_0 protein conserved in archaea - - - 0.00007493 55.0
CSH2_k127_3126744_0 Patched family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 399.0
CSH2_k127_3130687_0 PFAM periplasmic copper-binding - - - 0.000000002319 70.0
CSH2_k127_3130687_1 Small multi-drug export protein - - - 0.0001588 51.0
CSH2_k127_3141501_0 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.000000000000007866 78.0
CSH2_k127_3142178_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.38e-309 975.0
CSH2_k127_3147494_0 response to heat - - - 0.000000000000002892 79.0
CSH2_k127_316332_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00125 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002544 286.0
CSH2_k127_316332_1 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000006716 212.0
CSH2_k127_316332_2 4Fe-4S dicluster domain K03390,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000001764 94.0
CSH2_k127_316332_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000006473 69.0
CSH2_k127_3165478_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K01092 - 3.1.3.25 0.00000000000000000000005573 109.0
CSH2_k127_3165478_1 MobA-like NTP transferase domain - - - 0.000000253 61.0
CSH2_k127_3183209_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000006154 230.0
CSH2_k127_3183209_1 metal ion binding - - - 0.0000000000000000000000000000755 124.0
CSH2_k127_3183209_2 potassium uptake protein TrkH K03498 - - 0.00000000000001601 81.0
CSH2_k127_3205221_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 461.0
CSH2_k127_3205221_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000004433 164.0
CSH2_k127_3214571_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 336.0
CSH2_k127_3219471_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000008402 130.0
CSH2_k127_3219471_1 - - - - 0.000000000001598 69.0
CSH2_k127_3219471_2 Tetratricopeptide repeat - - - 0.000000006181 68.0
CSH2_k127_3229582_0 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 532.0
CSH2_k127_3229582_1 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002454 259.0
CSH2_k127_3229582_2 PFAM regulatory protein, ArsR K21903 - - 0.0000000000002336 75.0
CSH2_k127_3229582_3 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.000001171 51.0
CSH2_k127_3230305_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 451.0
CSH2_k127_3230305_1 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003624 299.0
CSH2_k127_3237575_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004276 281.0
CSH2_k127_3237575_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000009087 172.0
CSH2_k127_3243384_0 PFAM Radical SAM domain protein K07129 - - 0.000000000000000000000000000000000000000000000294 176.0
CSH2_k127_3243384_1 Tetratricopeptide repeat - - - 0.000000002782 70.0
CSH2_k127_324957_0 acid phosphatase activity K03651 - 3.1.4.53 0.000000001861 68.0
CSH2_k127_324957_1 Glycosyl hydrolase family 81 - - - 0.00008315 55.0
CSH2_k127_3254884_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 442.0
CSH2_k127_3254884_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000005316 193.0
CSH2_k127_3254884_2 Mur ligase middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000008594 197.0
CSH2_k127_3254884_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.000000000000000000000000000000000005273 151.0
CSH2_k127_3265409_0 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000006897 165.0
CSH2_k127_3265409_1 Di-glucose binding within endoplasmic reticulum - - - 0.00007977 49.0
CSH2_k127_3279472_0 Uncharacterized protein family UPF0004 K15865 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 301.0
CSH2_k127_3279472_1 Glutamine synthetase, beta-Grasp domain K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000003392 279.0
CSH2_k127_3279472_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000007179 66.0
CSH2_k127_3282299_0 Flavodoxin - - - 0.0000000000000000000000000000000000005693 145.0
CSH2_k127_3282299_1 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000006445 104.0
CSH2_k127_3286395_0 Transcriptional regulator K11924 - - 0.000000000001063 71.0
CSH2_k127_3288438_0 Formiminotransferase-cyclodeaminase K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 449.0
CSH2_k127_3288438_1 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.00000000000000000000000000001494 126.0
CSH2_k127_329386_0 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002642 253.0
CSH2_k127_329386_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000001422 218.0
CSH2_k127_3304669_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000299 60.0
CSH2_k127_3305576_0 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000001287 190.0
CSH2_k127_3305576_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000001669 158.0
CSH2_k127_3305576_2 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K17686 - 3.6.3.54 0.000000000000000000000000000002153 123.0
CSH2_k127_3305576_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000004916 93.0
CSH2_k127_3305576_4 PRC-barrel domain - - - 0.00000000000001721 79.0
CSH2_k127_3305576_5 helix_turn_helix ASNC type K05800 - - 0.0000005358 58.0
CSH2_k127_3325805_0 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 473.0
CSH2_k127_3325805_1 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000001192 205.0
CSH2_k127_3325805_2 Belongs to the UPF0200 family - - - 0.0000000000000000001092 94.0
CSH2_k127_3325805_3 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.00000000000005328 73.0
CSH2_k127_3325805_4 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000006104 66.0
CSH2_k127_3325805_5 protein conserved in archaea - - - 0.000002566 60.0
CSH2_k127_3333621_0 GatB/GatE catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 424.0
CSH2_k127_3333621_1 Outer membrane protein Omp28 - - - 0.0002152 54.0
CSH2_k127_3348571_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.00000000000000000000000000009116 117.0
CSH2_k127_3350907_0 - - - - 0.000000000000000000000000000000000001481 142.0
CSH2_k127_3350907_1 FAD dependent oxidoreductase - - - 0.00000000000001622 86.0
CSH2_k127_3350907_2 DNA binding - - - 0.0000002119 61.0
CSH2_k127_3365067_0 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001629 154.0
CSH2_k127_3365067_1 DHHA1 domain K07463 - - 0.0000000000000015 85.0
CSH2_k127_3365067_2 Peptidase family M28 - - - 0.00000004638 62.0
CSH2_k127_3384796_0 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 499.0
CSH2_k127_3384796_1 ABC transporter K01990 - - 0.0009538 45.0
CSH2_k127_341749_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000002927 185.0
CSH2_k127_341749_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000549 89.0
CSH2_k127_341749_2 transporter - - - 0.0000001536 64.0
CSH2_k127_3438714_0 B12 binding domain - - - 0.000000000000000000000000000000000005721 143.0
CSH2_k127_344239_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 465.0
CSH2_k127_3443_0 type II secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008751 501.0
CSH2_k127_3443_1 KaiC K07331 - - 0.000000000000000000000000000000000000000000000000000000000003264 216.0
CSH2_k127_3443_2 archaeal flagellar protein F K07329 - - 0.000000000002971 72.0
CSH2_k127_3443_3 flagella protein K07327,K07328 - - 0.00000000001416 75.0
CSH2_k127_3443_4 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000002083 74.0
CSH2_k127_3443_5 Archaebacterial flagellin K07330 - - 0.0000003925 58.0
CSH2_k127_344756_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 349.0
CSH2_k127_3448885_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 389.0
CSH2_k127_3448885_1 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001197 274.0
CSH2_k127_3448885_2 Molybdenum cofactor synthesis domain - - - 0.00000000000000000000000000000006412 134.0
CSH2_k127_3449124_0 peptidase M4 thermolysin K01399,K08604 GO:0005575,GO:0005576 3.4.24.25,3.4.24.26 0.0000000002809 74.0
CSH2_k127_3451907_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000001212 166.0
CSH2_k127_3451907_1 Protein of unknown function TPD sequence-motif - - - 0.00000000000000000000000000000000000000002059 162.0
CSH2_k127_3451907_2 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000327 111.0
CSH2_k127_3451907_3 Helix-turn-helix domain - - - 0.00000000001525 69.0
CSH2_k127_3470684_0 Catalyzes the conversion of dihydroorotate to orotate K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 308.0
CSH2_k127_3470684_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000233 198.0
CSH2_k127_3470684_2 Conserved Protein - - - 0.00000000000000000000000000000000006739 143.0
CSH2_k127_3470684_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000006678 123.0
CSH2_k127_3473256_0 - - - - 0.000000000008897 79.0
CSH2_k127_3473256_1 Tetratricopeptide repeat - - - 0.0001888 55.0
CSH2_k127_3474131_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 449.0
CSH2_k127_3474131_1 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002428 274.0
CSH2_k127_3474131_2 Aminotransferase class I and II - - - 0.00000000000000000002197 98.0
CSH2_k127_3482686_0 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001621 269.0
CSH2_k127_3482686_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002084 261.0
CSH2_k127_3482686_2 oligopeptide dipeptide ABC transporter K02031 - - 0.00000000000000000001623 99.0
CSH2_k127_3490239_0 Thioredoxin-like - - - 0.0000000000000002236 87.0
CSH2_k127_3490239_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000004363 70.0
CSH2_k127_3502763_0 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 284.0
CSH2_k127_3502763_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008958 266.0
CSH2_k127_3502763_2 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000009487 193.0
CSH2_k127_3502763_3 rubredoxin - - - 0.000000000000000000000000000000000000000001153 160.0
CSH2_k127_3502763_4 Rubrerythrin - - - 0.000000000000000000000000000000000000001003 153.0
CSH2_k127_3505551_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.0000000000000000000000000000000000000005534 162.0
CSH2_k127_3505551_1 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000006938 159.0
CSH2_k127_3505551_2 COG1522 Transcriptional regulators - - - 0.000000006901 66.0
CSH2_k127_3505551_3 Archease protein family (MTH1598/TM1083) - - - 0.00001061 54.0
CSH2_k127_3523688_0 FG-GAP repeat - - - 0.0000000001195 74.0
CSH2_k127_3534680_0 DEAD DEAH box helicase domain protein K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 386.0
CSH2_k127_3537585_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 447.0
CSH2_k127_3537585_1 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.0000000000000000000000000000000000000000002896 163.0
CSH2_k127_3537585_2 Ribosomal protein S8e K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000000007174 140.0
CSH2_k127_3537585_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.0000000000004221 74.0
CSH2_k127_3545820_0 4-hydroxy-tetrahydrodipicolinate reductase K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 409.0
CSH2_k127_3545820_1 Pfam:KaiC - - - 0.000000000000000000000000000000000009122 147.0
CSH2_k127_3545820_2 Carboxymuconolactone decarboxylase family K01607,K03469 - 3.1.26.4,4.1.1.44 0.0000000000000000000000000000000124 130.0
CSH2_k127_3545820_4 metallopeptidase activity - - - 0.0000001222 63.0
CSH2_k127_3551085_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 314.0
CSH2_k127_3551085_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000003125 222.0
CSH2_k127_3551085_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000005993 217.0
CSH2_k127_3551085_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000007616 207.0
CSH2_k127_3551085_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000001282 130.0
CSH2_k127_3551495_0 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000281 275.0
CSH2_k127_3551495_1 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000004385 73.0
CSH2_k127_356302_0 PFAM HhH-GPD family protein K07457 - - 0.00000000000000000000000000000000000000000000000000000003013 204.0
CSH2_k127_356302_1 - - - - 0.00000000000000000000001509 105.0
CSH2_k127_3571896_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000457 228.0
CSH2_k127_3571896_1 myosin light chain kinase activity K12567 - 2.7.11.1 0.00000000000000000000000648 112.0
CSH2_k127_3600888_0 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000003924 186.0
CSH2_k127_3600888_1 Thioredoxin domain - - - 0.0000000135 62.0
CSH2_k127_3600888_2 alkyl hydroperoxide reductase activity - - - 0.0005067 45.0
CSH2_k127_3613291_0 Circadian clock protein KaiC K08482 - - 0.000000000000001814 86.0
CSH2_k127_3614283_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 415.0
CSH2_k127_3614283_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 307.0
CSH2_k127_3624137_0 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000008725 92.0
CSH2_k127_3624137_1 Bacterial Ig-like domain (group 3) - - - 0.00000001831 68.0
CSH2_k127_3624747_0 Signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000000000000009801 156.0
CSH2_k127_3624747_1 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.0000000000000000000000000000000716 136.0
CSH2_k127_3630057_0 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008065 276.0
CSH2_k127_3630057_1 CBD_II K01179,K03933 - 3.2.1.4 0.000002058 61.0
CSH2_k127_3637982_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K00441 - 1.12.98.1 0.0000000000000000000000000000000002114 146.0
CSH2_k127_3637982_1 Cadherin repeats. - - - 0.0000000000000005336 92.0
CSH2_k127_3646989_0 Cellulose 1,4-beta-cellobiosidase - - - 0.000314 48.0
CSH2_k127_3658919_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1023.0
CSH2_k127_3658919_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 361.0
CSH2_k127_3658919_2 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000001386 231.0
CSH2_k127_3658919_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000001663 211.0
CSH2_k127_3658919_4 4Fe-4S dicluster domain - - - 0.0000000002409 63.0
CSH2_k127_3671892_0 BadF BadG BcrA BcrD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 518.0
CSH2_k127_3689011_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 412.0
CSH2_k127_369062_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000008086 168.0
CSH2_k127_369062_1 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000002078 137.0
CSH2_k127_369062_2 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000005891 92.0
CSH2_k127_370591_0 deoxyribonuclease I activity K06131,K06915 - - 0.000000000000000000000002523 121.0
CSH2_k127_3715150_0 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000003043 217.0
CSH2_k127_3715150_1 PFAM DEAD_2 domain protein K10844 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0043139,GO:0048037,GO:0051276,GO:0051536,GO:0051539,GO:0051540,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 0.000005896 56.0
CSH2_k127_3718313_0 PFAM PKD domain - - - 0.000005176 59.0
CSH2_k127_3718313_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00003634 56.0
CSH2_k127_3731097_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 409.0
CSH2_k127_3731097_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 298.0
CSH2_k127_3744230_0 exonuclease K07502 - - 0.00000000000000000000000000000000000000000000000003901 187.0
CSH2_k127_3744230_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.0000000000000000000000000000000001416 139.0
CSH2_k127_3744240_0 leucyl-tRNA aminoacylation K01869 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 410.0
CSH2_k127_3751623_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 335.0
CSH2_k127_3751623_1 Right handed beta helix region - - - 0.00004235 54.0
CSH2_k127_3762687_0 sarcosine oxidase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 529.0
CSH2_k127_3762687_1 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000509 152.0
CSH2_k127_3772588_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 618.0
CSH2_k127_3772588_1 polyphosphate kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 565.0
CSH2_k127_3772588_2 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000001729 244.0
CSH2_k127_3773349_0 FRG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 340.0
CSH2_k127_3773349_1 PKD domain - - - 0.000000000000000000000000000000000000002243 166.0
CSH2_k127_3773349_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000001048 124.0
CSH2_k127_3823892_0 Belongs to the thiolase family K00626 - 2.3.1.9 2.326e-261 810.0
CSH2_k127_3823892_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000198 254.0
CSH2_k127_388832_0 amidohydrolase - - - 0.0000000000000000000000006226 119.0
CSH2_k127_388832_1 TIGRFAM geranylgeranyl reductase family - - - 0.00000000000000000000005058 102.0
CSH2_k127_3891238_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001419 256.0
CSH2_k127_3891238_1 Belongs to the peptidase S1B family - - - 0.0000000009468 70.0
CSH2_k127_3891238_2 - - - - 0.00008125 51.0
CSH2_k127_3897367_0 PKD domain - - - 0.000000000006092 79.0
CSH2_k127_3897367_1 peptidase M4 thermolysin K01399,K08604 GO:0005575,GO:0005576 3.4.24.25,3.4.24.26 0.0000005046 63.0
CSH2_k127_3901449_0 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000004847 227.0
CSH2_k127_3901449_1 DHH family - - - 0.000000000000000000000000000000000000007648 160.0
CSH2_k127_3901449_2 Binds to the 23S rRNA K02921 - - 0.00000000000000000002871 95.0
CSH2_k127_3901449_3 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016043,GO:0016272,GO:0022607,GO:0032991,GO:0034622,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051087,GO:0051131,GO:0065003,GO:0071840 - 0.0000000000001837 75.0
CSH2_k127_3901449_4 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.000000004404 60.0
CSH2_k127_3905279_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 336.0
CSH2_k127_3905279_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000006166 197.0
CSH2_k127_3905279_2 TIGRFAM transcriptional regulator, AbrB family - - - 0.00000009437 57.0
CSH2_k127_3909983_0 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000000000000000000000000000000000000000000000001046 230.0
CSH2_k127_3914038_0 extracellular matrix structural constituent - - - 0.00000000000105 82.0
CSH2_k127_3928812_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 308.0
CSH2_k127_3928812_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000004088 199.0
CSH2_k127_3928812_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000004367 179.0
CSH2_k127_3928812_3 Belongs to the thioredoxin family K03671 - - 0.000000000000000000003725 102.0
CSH2_k127_3928812_4 4Fe-4S binding domain - - - 0.0000002685 59.0
CSH2_k127_3943630_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 300.0
CSH2_k127_3943630_1 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000000000000000001449 211.0
CSH2_k127_3943630_2 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000004771 143.0
CSH2_k127_3943630_3 chlorophyll binding K02519,K04043,K07114,K07288 - - 0.0000000000004142 83.0
CSH2_k127_3954437_0 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 308.0
CSH2_k127_3954437_1 FtsX-like permease family - - - 0.0000000000000000000000000000000000107 155.0
CSH2_k127_3957418_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000007181 212.0
CSH2_k127_3957418_1 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000000000000000000000000000000000001572 184.0
CSH2_k127_3957418_2 RibD C-terminal domain K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000003237 177.0
CSH2_k127_3957418_3 - - - - 0.00000007245 59.0
CSH2_k127_4010296_0 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000001462 138.0
CSH2_k127_4010296_1 Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000000000000001977 137.0
CSH2_k127_4014462_0 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000003259 204.0
CSH2_k127_4014462_1 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.000003989 49.0
CSH2_k127_4038666_0 Anticodon binding domain K01880 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 485.0
CSH2_k127_4038666_1 - - - - 0.00000005186 58.0
CSH2_k127_4067476_0 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000174 273.0
CSH2_k127_4067476_1 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000005454 171.0
CSH2_k127_4067476_2 TIGRFAM ribosomal protein L30P K02907 - - 0.000000000000000000000000000000000000000000007037 167.0
CSH2_k127_4067476_3 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000035 141.0
CSH2_k127_4067476_4 binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0001665 45.0
CSH2_k127_4068921_0 Transglutaminase-like superfamily - - - 0.0000000000295 75.0
CSH2_k127_4068921_1 Domain of unknown function DUF87 - - - 0.00000005882 66.0
CSH2_k127_4068921_2 ribosomal small subunit binding - - - 0.0000007356 60.0
CSH2_k127_4071531_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000164 65.0
CSH2_k127_4092449_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 407.0
CSH2_k127_4092449_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000003595 182.0
CSH2_k127_4092449_2 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000002773 166.0
CSH2_k127_4149476_0 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000008031 243.0
CSH2_k127_4149476_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000004315 72.0
CSH2_k127_4149476_2 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0002177 44.0
CSH2_k127_4164960_0 Cadherin repeats. - - - 0.0005886 53.0
CSH2_k127_4189395_0 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000002313 229.0
CSH2_k127_4189395_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000007177 191.0
CSH2_k127_4202817_0 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.0000000000000000000000000000008462 138.0
CSH2_k127_4204760_0 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.0000000000000000000001276 100.0
CSH2_k127_4206122_0 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000816 224.0
CSH2_k127_4206122_1 FtsX-like permease family K02004 - - 0.000799 49.0
CSH2_k127_4211315_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 499.0
CSH2_k127_4221903_0 PQQ-like domain - - - 0.000007049 59.0
CSH2_k127_4255270_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 384.0
CSH2_k127_426674_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 5.167e-310 965.0
CSH2_k127_426674_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.242e-208 655.0
CSH2_k127_426674_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000002767 162.0
CSH2_k127_426674_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000001192 74.0
CSH2_k127_4303131_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.309e-300 932.0
CSH2_k127_4303131_1 PFAM peptidase M50 - - - 0.0000000000000000000000000000000002045 141.0
CSH2_k127_4303131_2 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000007246 138.0
CSH2_k127_4303131_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000001164 115.0
CSH2_k127_4303131_4 - - - - 0.00000000000000000004452 96.0
CSH2_k127_4310371_0 RNA cap guanine-N2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001832 249.0
CSH2_k127_4310371_1 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000262 167.0
CSH2_k127_4310371_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000001017 164.0
CSH2_k127_4310371_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000006751 135.0
CSH2_k127_4310371_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000000000000000000001181 134.0
CSH2_k127_4310371_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000003457 121.0
CSH2_k127_4310371_6 PKD domain containing protein - - - 0.000000003527 61.0
CSH2_k127_4311506_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 329.0
CSH2_k127_4311506_1 GvpD gas vesicle protein - - - 0.0000000000000000000000000000000001553 141.0
CSH2_k127_4311506_2 Belongs to the UPF0273 family - - - 0.00000005874 66.0
CSH2_k127_4312588_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 306.0
CSH2_k127_4312588_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000006287 225.0
CSH2_k127_4312588_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.0000000000000000000000000000000000009076 143.0
CSH2_k127_4312588_3 PFAM phosphate transporter K03306 - - 0.000000000000001389 79.0
CSH2_k127_4334993_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 416.0
CSH2_k127_4335673_0 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000104 277.0
CSH2_k127_4335673_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 261.0
CSH2_k127_4335673_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001223 190.0
CSH2_k127_4335673_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.000000000000000000000000007012 113.0
CSH2_k127_4335673_4 TIGRFAM Outer membrane protein K13735,K20276 - - 0.00009893 55.0
CSH2_k127_4360199_0 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 390.0
CSH2_k127_4360199_1 NUDIX domain - - - 0.00000000000000000000006264 104.0
CSH2_k127_4360199_2 Thiamine-binding protein - - - 0.00000000000000000002921 94.0
CSH2_k127_4360199_3 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000005272 89.0
CSH2_k127_4360199_4 PFAM Aminotransferase class I and II - - - 0.00000009628 60.0
CSH2_k127_4366993_0 Major facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001466 267.0
CSH2_k127_4366993_2 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000005431 182.0
CSH2_k127_4366993_3 Flavodoxin domain - - - 0.0000000000000000000000004762 112.0
CSH2_k127_4377151_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 441.0
CSH2_k127_4377151_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 407.0
CSH2_k127_4377151_2 Sporulation initiation inhibitor protein Soj K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 319.0
CSH2_k127_4377151_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 315.0
CSH2_k127_4377151_4 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00009446 54.0
CSH2_k127_43797_0 Fibronectin type III domain protein K06882 - - 0.00000001382 68.0
CSH2_k127_4396095_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000002132 194.0
CSH2_k127_4396095_1 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000006865 149.0
CSH2_k127_4396095_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000001948 123.0
CSH2_k127_4396095_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000008007 108.0
CSH2_k127_4396095_4 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000001517 108.0
CSH2_k127_4396095_5 Binds to the 23S rRNA K02896 - - 0.00000000000000000005793 91.0
CSH2_k127_4396844_0 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 458.0
CSH2_k127_4396844_1 TIGRFAM RarD protein K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003783 286.0
CSH2_k127_4396844_2 tRNA pseudouridine synthase D K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000005501 261.0
CSH2_k127_4396844_3 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000267 126.0
CSH2_k127_4396844_4 parallel beta-helix repeat K03671 - - 0.000002447 60.0
CSH2_k127_4428283_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000772 205.0
CSH2_k127_4428283_1 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.000000000000000000000000002331 117.0
CSH2_k127_4428283_2 Belongs to the peptidase S8 family K13735,K20276,K21449 - - 0.0007796 52.0
CSH2_k127_4428612_0 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.00000000000000000000000000000000000000000009832 168.0
CSH2_k127_4428612_1 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000001307 162.0
CSH2_k127_4466945_0 Belongs to the CarB family K01955 - 6.3.5.5 2.223e-321 1000.0
CSH2_k127_446848_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 378.0
CSH2_k127_446848_1 protein conserved in archaea - - - 0.00002453 55.0
CSH2_k127_4486875_0 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002988 286.0
CSH2_k127_4486875_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000009057 67.0
CSH2_k127_4513827_0 entry into host K13735 - - 0.0008692 52.0
CSH2_k127_4516038_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 1.453e-236 740.0
CSH2_k127_4516038_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000005771 91.0
CSH2_k127_4516038_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000005342 78.0
CSH2_k127_4516038_3 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde K01629 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008994,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.2.19 0.000000000001272 76.0
CSH2_k127_454327_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000001433 236.0
CSH2_k127_454327_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000002219 163.0
CSH2_k127_454327_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000002942 135.0
CSH2_k127_4550183_0 DNA-directed 5'-3' RNA polymerase activity K01387 - 3.4.24.3 0.000000000000002901 91.0
CSH2_k127_4550183_1 gluconolactonase activity K13276,K14274 GO:0005575,GO:0005576 - 0.0007088 53.0
CSH2_k127_4553389_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000002755 240.0
CSH2_k127_4553389_1 chromosome segregation and condensation protein ScpA K05896 - - 0.0000000001545 68.0
CSH2_k127_4557641_0 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000001798 81.0
CSH2_k127_4557641_1 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000251 55.0
CSH2_k127_4561278_0 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 6.474e-233 732.0
CSH2_k127_4601720_0 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 574.0
CSH2_k127_4601720_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003108 278.0
CSH2_k127_4601720_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000001017 232.0
CSH2_k127_4621735_0 Response regulator, receiver K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 582.0
CSH2_k127_4623691_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000004073 86.0
CSH2_k127_4623691_1 peptidyl-tyrosine sulfation - - - 0.000000002977 67.0
CSH2_k127_4634186_0 Pro-kumamolisin, activation domain - - - 0.000005418 60.0
CSH2_k127_4634863_0 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000004562 178.0
CSH2_k127_4634863_1 ABC transporter (Permease) K02004 - - 0.00000000000000001184 96.0
CSH2_k127_4637627_0 PFAM SOUL heme-binding protein - - - 0.0000000000000000000000000000000000001482 147.0
CSH2_k127_4637627_1 - - - - 0.0000000000000000000000001427 112.0
CSH2_k127_4639492_0 UPF0313 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 400.0
CSH2_k127_4639492_1 Papain family cysteine protease - - - 0.000000000009946 74.0
CSH2_k127_4640330_0 Heat shock 70 kDa protein K04043 - - 1.562e-238 752.0
CSH2_k127_4640330_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000007487 171.0
CSH2_k127_4640330_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000004687 80.0
CSH2_k127_4641833_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000002776 151.0
CSH2_k127_4641833_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000004571 68.0
CSH2_k127_4643736_0 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000004123 170.0
CSH2_k127_4653674_0 peptidase activity - - - 0.00000000000000000001808 104.0
CSH2_k127_4656548_0 Alpha-L-glutamate - - - 0.00000000000000000000000000000000000000000000000000000003038 210.0
CSH2_k127_4667057_0 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 487.0
CSH2_k127_4667057_1 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000003931 169.0
CSH2_k127_4667057_2 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000484 167.0
CSH2_k127_4667057_3 Type II secretion system K07333 - - 0.00000000000000000000000000000000000352 154.0
CSH2_k127_4667057_5 mitochondrial outer membrane translocase receptor TOM70 K17768 GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005742,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007006,GO:0007007,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0017038,GO:0019867,GO:0030150,GO:0030943,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031306,GO:0031307,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032592,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044743,GO:0045039,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0072657,GO:0090150,GO:0090151,GO:0098573,GO:0098588,GO:0098796,GO:0098798,GO:0098799,GO:0098805,GO:1990542 - 0.00005036 55.0
CSH2_k127_470227_0 Cell division protein 48, CDC48, domain 2 K13525 - - 4.954e-265 835.0
CSH2_k127_470227_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 454.0
CSH2_k127_470227_2 Fibronectin type 3 domain K20276 - - 0.00000000000000000000000000000000000008489 165.0
CSH2_k127_470227_3 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.0000000000000000208 89.0
CSH2_k127_470227_4 - - - - 0.00000000001683 72.0
CSH2_k127_470227_5 DNAj-like protein - - - 0.0000000001251 72.0
CSH2_k127_470227_6 Belongs to the peptidase S8 family - - - 0.0000000001823 75.0
CSH2_k127_470227_7 PRC-barrel domain protein - - - 0.00000004968 57.0
CSH2_k127_470227_8 transposition, RNA-mediated - - - 0.0000002885 58.0
CSH2_k127_470227_9 H ACA RNA-protein complex K07569 - - 0.000001692 56.0
CSH2_k127_4718308_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 608.0
CSH2_k127_4718308_1 Belongs to the serpin family K13963 GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005576,GO:0005615,GO:0008150,GO:0009892,GO:0010466,GO:0010605,GO:0010951,GO:0019222,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0032268,GO:0032269,GO:0043086,GO:0044092,GO:0044421,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0080090,GO:0098772 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 325.0
CSH2_k127_4718308_2 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000008672 190.0
CSH2_k127_4718308_3 SERine Proteinase INhibitors K13963 GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005576,GO:0005615,GO:0008150,GO:0009892,GO:0010466,GO:0010605,GO:0010951,GO:0019222,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0032268,GO:0032269,GO:0043086,GO:0044092,GO:0044421,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0080090,GO:0098772 - 0.000000000000000000000008548 107.0
CSH2_k127_4751316_0 amine dehydrogenase activity K20276 - - 0.000000000000000000000000000002551 141.0
CSH2_k127_47683_0 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007986 256.0
CSH2_k127_4796101_0 Response regulator receiver domain - - - 0.00000000000000000000000002438 112.0
CSH2_k127_4796101_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872,K07050 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000002559 108.0
CSH2_k127_4796101_2 Histidine kinase-like ATPases - - - 0.00000004517 63.0
CSH2_k127_4796101_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00001093 54.0
CSH2_k127_4796101_4 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0008 48.0
CSH2_k127_4796609_0 neurotransmitter:sodium symporter activity K03308,K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 391.0
CSH2_k127_4829411_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000572 251.0
CSH2_k127_4829411_1 Protein of unknown function (DUF531) K09725 - - 0.000000000000000000000000000000000000000000000004722 179.0
CSH2_k127_4829411_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000003329 111.0
CSH2_k127_4829411_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000006736 56.0
CSH2_k127_4829650_0 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000699 202.0
CSH2_k127_4836788_0 Putative heavy-metal-binding - - - 0.00004549 54.0
CSH2_k127_4836788_1 Peptidase A24A, prepilin type IV K02278,K07991 - 3.4.23.43,3.4.23.52 0.0002841 48.0
CSH2_k127_4843680_0 chlorophyll binding - - - 0.0000009928 63.0
CSH2_k127_484519_0 PFAM 2-hydroxyglutaryl-CoA dehydratase D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 319.0
CSH2_k127_484519_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000008619 110.0
CSH2_k127_4850442_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 3.526e-239 747.0
CSH2_k127_4850442_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 332.0
CSH2_k127_4858172_0 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.000000000000000000000000000000000000000000000000000001029 201.0
CSH2_k127_4858172_1 Glycosyl hydrolases family 18 K01183 - 3.2.1.14 0.0003547 53.0
CSH2_k127_4871722_0 peptidase M4 thermolysin K01399,K08604 GO:0005575,GO:0005576 3.4.24.25,3.4.24.26 0.00000000000000001599 98.0
CSH2_k127_4872763_0 PFAM PQQ enzyme repeat - - - 0.000000002217 70.0
CSH2_k127_487310_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 463.0
CSH2_k127_4876440_0 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro K01101 - 3.1.3.41 0.00000000000000000000000000000000000000007674 161.0
CSH2_k127_4876440_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000001535 154.0
CSH2_k127_4876440_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000007857 138.0
CSH2_k127_4876440_3 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000000000000000000000000001323 119.0
CSH2_k127_4876440_4 DnaJ molecular chaperone homology domain K05516 - - 0.00000001673 66.0
CSH2_k127_4876440_5 - - - - 0.000107 49.0
CSH2_k127_489669_0 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000001472 177.0
CSH2_k127_489669_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000009788 160.0
CSH2_k127_4899775_0 binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 479.0
CSH2_k127_4900256_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.722e-208 663.0
CSH2_k127_4900256_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 407.0
CSH2_k127_4900256_2 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 307.0
CSH2_k127_4900256_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573,K12585 - - 0.00000000000000000000000000003025 134.0
CSH2_k127_4900256_4 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K03148,K21029 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779 2.7.7.73,2.7.7.80 0.00003259 46.0
CSH2_k127_4902595_0 ABC transporter, ATP-binding protein K02074,K09817 - - 0.0000000000000000000000000000000000000000000000000000002346 205.0
CSH2_k127_4902595_1 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000005447 180.0
CSH2_k127_4902595_2 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.00000000004947 66.0
CSH2_k127_4902595_3 PFAM glutaredoxin - - - 0.000000001843 59.0
CSH2_k127_4909153_0 - - - - 0.0000000002837 72.0
CSH2_k127_4909153_1 Bacterial transcriptional activator domain - - - 0.0001173 54.0
CSH2_k127_4915439_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 480.0
CSH2_k127_4917933_0 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 489.0
CSH2_k127_4917933_1 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 323.0
CSH2_k127_4917933_2 Belongs to the phosphohexose mutase family K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000003892 255.0
CSH2_k127_4929141_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 364.0
CSH2_k127_4929141_1 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000003877 168.0
CSH2_k127_4929141_2 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000008698 150.0
CSH2_k127_4931942_0 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000003561 197.0
CSH2_k127_4931942_1 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.000000000000000000000000000000002615 135.0
CSH2_k127_4931942_2 Membrane - - - 0.00001388 58.0
CSH2_k127_4933835_0 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000001362 241.0
CSH2_k127_4933835_1 Lrp/AsnC ligand binding domain - - - 0.000000002302 60.0
CSH2_k127_4933835_2 ABC-type cobalt transport system, permease component CbiQ K16785 - - 0.00008953 53.0
CSH2_k127_4937823_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000001834 210.0
CSH2_k127_4937823_1 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000004272 168.0
CSH2_k127_4943946_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 595.0
CSH2_k127_4943946_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 437.0
CSH2_k127_4943946_2 - - - - 0.000000000000005914 78.0
CSH2_k127_4943946_3 PFAM acyl-CoA dehydrogenase-like Acyl-CoA dehydrogenase, type 2-like K00252 - 1.3.8.6 0.000000004419 62.0
CSH2_k127_4944022_0 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.000000000000000000000002767 121.0
CSH2_k127_4944022_1 peptidase activity, acting on L-amino acid peptides K01179 - 3.2.1.4 0.0000000000000000418 97.0
CSH2_k127_4946852_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 550.0
CSH2_k127_4946852_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 491.0
CSH2_k127_495740_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 421.0
CSH2_k127_495740_1 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 346.0
CSH2_k127_4964661_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 320.0
CSH2_k127_4967563_0 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000000000000000000000000000000000000000002055 251.0
CSH2_k127_5010205_0 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 452.0
CSH2_k127_5010205_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000001972 156.0
CSH2_k127_5047342_0 HELICc2 K03722,K10844 - 3.6.4.12 0.0000000000000000000000000000000000000002474 156.0
CSH2_k127_5048164_0 PKD domain - - - 0.0000000000000000000000000000000000000000000000000000000000002364 241.0
CSH2_k127_5048164_1 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.000000000000000000000000000000000000000003089 175.0
CSH2_k127_5048164_2 Galactose oxidase, central domain - - - 0.000000000000000000000000000000000002064 146.0
CSH2_k127_505395_0 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000002289 233.0
CSH2_k127_505395_1 PFAM Fibronectin type III domain - - - 0.0000000000000000002168 104.0
CSH2_k127_505395_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0001904 52.0
CSH2_k127_507239_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000002563 221.0
CSH2_k127_5073445_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 522.0
CSH2_k127_5073445_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 433.0
CSH2_k127_507594_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.005e-225 707.0
CSH2_k127_5086779_0 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000000000000008068 196.0
CSH2_k127_5086779_1 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.000000000000000000000000000000000000000000000001163 184.0
CSH2_k127_5086779_2 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.0000000000000000000000000000001759 131.0
CSH2_k127_5086779_3 Single-stranded-DNA-specific exonuclease recj K07462 - - 0.0004512 44.0
CSH2_k127_5089666_0 endonuclease III K01142,K10773 - 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000006817 268.0
CSH2_k127_5089666_1 Subtilase family - - - 0.00000000000000000005276 100.0
CSH2_k127_5089666_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000008934 78.0
CSH2_k127_5089666_3 S-layer homology domain - - - 0.0000001871 62.0
CSH2_k127_510866_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1119.0
CSH2_k127_510866_1 PFAM multi antimicrobial extrusion protein MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 438.0
CSH2_k127_510866_2 PFAM Acyl-ACP thioesterase - - - 0.00000000000002471 77.0
CSH2_k127_5120016_0 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000003339 168.0
CSH2_k127_5120016_1 ferredoxin oxidoreductase K00179 - 1.2.7.8 0.000001828 51.0
CSH2_k127_5133464_0 Domain of unknown function (DUF1735) - - - 0.0002913 56.0
CSH2_k127_5133464_1 helix loop helix domain - - - 0.0006317 43.0
CSH2_k127_5133464_2 Bacterial Ig-like domain - - - 0.0006634 55.0
CSH2_k127_5135913_0 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 344.0
CSH2_k127_5135913_1 Belongs to the UPF0179 family K09730 - - 0.0000000000000000000000000001032 120.0
CSH2_k127_5141931_0 Cytochrome C assembly protein - - - 0.000000006063 62.0
CSH2_k127_5141931_1 Hep Hag repeat protein K01179 - 3.2.1.4 0.00006137 54.0
CSH2_k127_5141931_2 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0002544 44.0
CSH2_k127_5165644_0 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 486.0
CSH2_k127_5165644_1 Flavin containing amine oxidoreductase K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 313.0
CSH2_k127_5165644_2 lycopene cyclase - - - 0.00000000000000000000000000000000000000000004194 169.0
CSH2_k127_5180218_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002352 259.0
CSH2_k127_5180218_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000000000000000000000000000000003321 240.0
CSH2_k127_5180218_2 S-layer protein - - - 0.00000000000002492 86.0
CSH2_k127_5189752_0 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.0000000000000000000000000002018 121.0
CSH2_k127_5189752_1 UvrD REP helicase K16899 - 3.6.4.12 0.0000000000000000000000000009303 132.0
CSH2_k127_5200718_0 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000953 162.0
CSH2_k127_5200718_1 PKD domain - - - 0.0000000000000000000000000000000001809 154.0
CSH2_k127_5200718_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000001541 127.0
CSH2_k127_5203470_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 520.0
CSH2_k127_5203470_1 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006427 244.0
CSH2_k127_5203470_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000006542 228.0
CSH2_k127_5203470_3 Hydrogenase expression formation protein (HypD) K04654 - - 0.000000000000000000000000000000000000000000005395 167.0
CSH2_k127_5203470_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000002017 96.0
CSH2_k127_5203470_5 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000002249 84.0
CSH2_k127_5208235_0 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 421.0
CSH2_k127_5208235_1 EamA-like transporter family - - - 0.000000000000000000000000000001434 133.0
CSH2_k127_5208235_2 Alanine dehydrogenase/PNT, N-terminal domain K00290 - 1.5.1.7 0.0000008115 52.0
CSH2_k127_5208235_3 Major Facilitator Superfamily - - - 0.000003105 54.0
CSH2_k127_5232177_0 Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 356.0
CSH2_k127_5232177_1 MarR family - - - 0.00000000000000000000000000000000002892 139.0
CSH2_k127_5232177_2 Short-chain dehydrogenase reductase sdr - - - 0.000000000000004932 78.0
CSH2_k127_5233260_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00008743 55.0
CSH2_k127_5256874_0 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000001821 155.0
CSH2_k127_5256874_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000001943 75.0
CSH2_k127_5256874_2 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.000002886 62.0
CSH2_k127_5256874_3 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00001542 50.0
CSH2_k127_5258133_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000001794 182.0
CSH2_k127_5258133_1 Thioredoxin K03671 - - 0.0004972 53.0
CSH2_k127_5264973_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000008666 215.0
CSH2_k127_5264973_1 Nucleotidyl transferase K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000003349 198.0
CSH2_k127_5264973_2 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000003966 160.0
CSH2_k127_5278196_0 Fcf1 K07158 - - 0.000000000000000002451 89.0
CSH2_k127_5280587_0 Methyltransferase type 11 - - - 0.00000000000000000000000000000008123 128.0
CSH2_k127_5280587_1 nitrogen fixation - - - 0.00000000000000000000000001927 117.0
CSH2_k127_5280587_2 Protein of unknown function DUF134 K06933 - - 0.00000000000000000116 94.0
CSH2_k127_5286764_0 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 365.0
CSH2_k127_5286764_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000001185 194.0
CSH2_k127_5297159_0 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000008304 156.0
CSH2_k127_5309762_0 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor - - - 0.000000000007338 78.0
CSH2_k127_5309762_1 Oxidoreductase molybdopterin binding domain - - - 0.000000000189 70.0
CSH2_k127_5322441_0 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.0000005435 63.0
CSH2_k127_5327516_0 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 432.0
CSH2_k127_5333470_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000004733 248.0
CSH2_k127_5333470_1 metal-dependent membrane protease K07052 - - 0.0000000000000001424 91.0
CSH2_k127_5334223_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 2.637e-226 714.0
CSH2_k127_5334223_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000004435 277.0
CSH2_k127_5352091_0 PFAM type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006033 261.0
CSH2_k127_5352091_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000001232 118.0
CSH2_k127_5388280_0 SMART Parallel beta-helix repeat - - - 0.00000000000002231 89.0
CSH2_k127_5394933_0 Thiamine-phosphate synthase K22206 - - 0.000000000000000000000000000000000006118 148.0
CSH2_k127_5394933_1 ABC-type thiamine transport system, periplasmic component K02064 - - 0.00000000000000000000000000001099 125.0
CSH2_k127_5404633_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000002344 101.0
CSH2_k127_5404633_1 protein conserved in archaea - - - 0.0000000004461 71.0
CSH2_k127_5416321_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000003397 218.0
CSH2_k127_5416321_1 Rhs Family - - - 0.00000000008125 71.0
CSH2_k127_541826_0 von Willebrand factor, type A - - - 0.0000000000000000003138 100.0
CSH2_k127_5431859_0 adenyl ribonucleotide binding - - - 0.000000000000000000000000000000000000974 146.0
CSH2_k127_5431859_1 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000007608 138.0
CSH2_k127_5431859_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000799 91.0
CSH2_k127_5432932_0 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 315.0
CSH2_k127_5432932_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000004684 236.0
CSH2_k127_5432932_2 CYTH K05873 - 4.6.1.1 0.00000000000000000000000001494 117.0
CSH2_k127_5439433_0 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000004212 273.0
CSH2_k127_5439433_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000005732 213.0
CSH2_k127_5439987_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 601.0
CSH2_k127_5439987_1 oligoendopeptidase F K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000001137 190.0
CSH2_k127_5439987_2 Thioredoxin - - - 0.00000000000000000000001902 104.0
CSH2_k127_5454314_0 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001179 274.0
CSH2_k127_5454314_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000005068 184.0
CSH2_k127_5454314_2 TIGRFAM histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000007143 175.0
CSH2_k127_5454314_3 oxidoreductase activity - - - 0.000000000563 74.0
CSH2_k127_5455172_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 482.0
CSH2_k127_5455172_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000003727 176.0
CSH2_k127_5455172_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000297 150.0
CSH2_k127_5455172_3 Peptidase family M50 - - - 0.0000000000000000000000001689 117.0
CSH2_k127_5460882_0 CoA binding domain K09181 - - 0.00003487 47.0
CSH2_k127_5478987_0 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000002251 169.0
CSH2_k127_5478987_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000008041 138.0
CSH2_k127_5478987_2 Catalyzes the synthesis of GMP from XMP K01951,K03790 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 0.0000000008633 68.0
CSH2_k127_5482507_0 Putative sensor - - - 0.0000000000000000000000000000009674 132.0
CSH2_k127_5482507_1 PadR family transcriptional regulator K10947 - - 0.000000000000000000000000002957 117.0
CSH2_k127_5482507_2 PFAM ABC transporter related K02031,K02032 - - 0.0000000000000000000001569 98.0
CSH2_k127_5482507_3 PQ loop repeat K15383 - - 0.0000000000000000005476 87.0
CSH2_k127_5482507_4 - - - - 0.000299 52.0
CSH2_k127_5482590_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 352.0
CSH2_k127_5482590_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000297 208.0
CSH2_k127_5482590_2 Involved in the catabolism of quinolinic acid (QA) K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.00000000000000000000000000000000000000000000000009644 188.0
CSH2_k127_5482590_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000001121 159.0
CSH2_k127_5482590_4 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000001908 75.0
CSH2_k127_5484175_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 387.0
CSH2_k127_5484175_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 379.0
CSH2_k127_5484175_2 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 364.0
CSH2_k127_5484175_3 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 351.0
CSH2_k127_5484175_4 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000009173 154.0
CSH2_k127_5484175_5 cell redox homeostasis - - - 0.0000000000000000000000001154 109.0
CSH2_k127_5484175_6 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.000000007697 63.0
CSH2_k127_54878_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 435.0
CSH2_k127_54878_1 Protein conserved in bacteria K20276 - - 0.00000002637 67.0
CSH2_k127_5493480_0 self proteolysis - - - 0.0000000000000001044 94.0
CSH2_k127_5493480_1 oxidoreductase activity - - - 0.0003972 53.0
CSH2_k127_549727_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 591.0
CSH2_k127_549727_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 377.0
CSH2_k127_549727_2 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 304.0
CSH2_k127_549727_3 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 291.0
CSH2_k127_549727_4 - - - - 0.00000000000000000000000000000007137 132.0
CSH2_k127_549727_5 Hydrogenase maturation protease K03605 - - 0.00000000000000000001788 96.0
CSH2_k127_549727_6 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000000000000003937 89.0
CSH2_k127_5499450_0 von willebrand factor, type A K12549 - - 0.000000000001481 79.0
CSH2_k127_5519971_0 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000002689 98.0
CSH2_k127_5519971_1 Peptide transporter - - - 0.00000000003022 76.0
CSH2_k127_5522632_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000000000002564 156.0
CSH2_k127_5522632_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.0000000000000000003326 99.0
CSH2_k127_5522632_2 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000002059 84.0
CSH2_k127_5539516_0 Belongs to the peptidase S8 family - - - 0.0000001953 63.0
CSH2_k127_5541002_0 von Willebrand factor, type A K07114 - - 0.000000003419 69.0
CSH2_k127_5541002_1 PKD domain - - - 0.000006421 59.0
CSH2_k127_5544751_0 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000001317 226.0
CSH2_k127_5544751_1 PFAM ABC transporter K01990 - - 0.0000000000000000000000001792 109.0
CSH2_k127_5544751_2 Oxidoreductase molybdopterin binding domain - - - 0.0007416 52.0
CSH2_k127_5547301_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 6.074e-250 792.0
CSH2_k127_5547301_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 552.0
CSH2_k127_5572091_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000006907 241.0
CSH2_k127_5572091_1 COG3291 FOG PKD repeat K01387 GO:0005575,GO:0005576 3.4.24.3 0.000002775 60.0
CSH2_k127_560059_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000285 251.0
CSH2_k127_560059_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000166 52.0
CSH2_k127_5616705_0 tRNA processing K06864,K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001534 271.0
CSH2_k127_5616705_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:2000112,GO:2000765 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000005911 228.0
CSH2_k127_5616705_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000001018 107.0
CSH2_k127_5616705_3 utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000003196 50.0
CSH2_k127_5625532_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000001987 200.0
CSH2_k127_5625532_1 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000007559 200.0
CSH2_k127_5636080_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001468 284.0
CSH2_k127_5636080_1 PFAM ABC-2 type transporter K01992 - - 0.00005604 53.0
CSH2_k127_5674039_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 7.243e-225 709.0
CSH2_k127_5674039_1 Asparaginase K01424 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 614.0
CSH2_k127_5674039_2 integrin K06476,K06487,K06584 GO:0001775,GO:0002576,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005912,GO:0005924,GO:0005925,GO:0006810,GO:0006887,GO:0006950,GO:0007155,GO:0007160,GO:0007596,GO:0007599,GO:0008150,GO:0009611,GO:0009897,GO:0009986,GO:0009987,GO:0012505,GO:0012506,GO:0016020,GO:0016043,GO:0016192,GO:0022610,GO:0030054,GO:0030055,GO:0030141,GO:0030168,GO:0030198,GO:0030334,GO:0030335,GO:0030659,GO:0030667,GO:0031090,GO:0031091,GO:0031092,GO:0031410,GO:0031589,GO:0031982,GO:0032501,GO:0032879,GO:0032940,GO:0034109,GO:0040012,GO:0040017,GO:0042060,GO:0042802,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045595,GO:0045637,GO:0045652,GO:0046903,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0050817,GO:0050840,GO:0050878,GO:0050896,GO:0051179,GO:0051234,GO:0051239,GO:0051270,GO:0051272,GO:0065007,GO:0065008,GO:0070051,GO:0070062,GO:0070161,GO:0070527,GO:0071840,GO:0071944,GO:0097708,GO:0098552,GO:0098588,GO:0098609,GO:0098805,GO:0099503,GO:1903561,GO:1903706,GO:2000026,GO:2000145,GO:2000147 - 0.000046 54.0
CSH2_k127_5686839_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000005535 254.0
CSH2_k127_5686839_1 Binds to the 23S rRNA K02929 - - 0.000000000000000000000000000000000008791 137.0
CSH2_k127_5686839_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000001869 81.0
CSH2_k127_5686839_3 PFAM Ribosomal protein S27E K02978 - - 0.000000000003587 68.0
CSH2_k127_5697824_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000343 136.0
CSH2_k127_5705889_0 Pfam:KaiC - - - 0.0000000000000000000000000000000000000284 149.0
CSH2_k127_5705889_1 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000001597 132.0
CSH2_k127_5705889_2 DNA-binding transcription factor activity - - - 0.00000000000000000000000007208 118.0
CSH2_k127_5715345_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.00000001052 68.0
CSH2_k127_5733835_0 Fibronectin type III domain - - - 0.00000000000000000000000000000002524 147.0
CSH2_k127_5733835_1 Calcium-binding protein K02183 - - 0.000000002159 66.0
CSH2_k127_5733835_2 protein conserved in archaea - - - 0.0000000299 62.0
CSH2_k127_5733835_3 bacterial-type flagellum-dependent cell motility K01119,K06113,K12685,K20276 - 3.1.3.6,3.1.4.16,3.2.1.99 0.000008132 59.0
CSH2_k127_5754728_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005794 230.0
CSH2_k127_5754728_1 Carboxypeptidase regulatory-like domain - - - 0.0001993 51.0
CSH2_k127_5761671_0 Fibronectin type III domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002444 259.0
CSH2_k127_5761671_1 metallopeptidase activity - - - 0.000000000000000000000000000008675 138.0
CSH2_k127_5761671_2 PQQ-like domain - - - 0.000000002132 70.0
CSH2_k127_5761671_3 Belongs to the glycosyl hydrolase 18 family - - - 0.0000009793 63.0
CSH2_k127_5769017_0 SMART Parallel beta-helix repeat - - - 0.00000001992 67.0
CSH2_k127_5784296_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 467.0
CSH2_k127_5784296_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 376.0
CSH2_k127_5810849_0 Citrate lyase alpha subunit K01643 - 2.8.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 436.0
CSH2_k127_5810849_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000002694 188.0
CSH2_k127_5811820_0 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000006246 107.0
CSH2_k127_5811820_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11747 - - 0.00000000000000008959 91.0
CSH2_k127_5817595_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 451.0
CSH2_k127_5817595_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 437.0
CSH2_k127_5819713_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 2.144e-227 720.0
CSH2_k127_5819713_1 Dodecin K09165 - - 0.000000000000000000000001458 104.0
CSH2_k127_5819713_2 Protein of unknown function (DUF521) K09123 - - 0.000000000000000003097 91.0
CSH2_k127_5825890_0 Fibronectin type 3 domain K01179,K06882 - 3.2.1.4 0.00000000002415 78.0
CSH2_k127_5825890_1 Galactose oxidase, central domain - - - 0.0006345 53.0
CSH2_k127_5831389_0 manganese ion transmembrane transporter activity - - - 0.000000000000000000000000000000000002319 144.0
CSH2_k127_584360_0 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 567.0
CSH2_k127_584360_1 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000001292 231.0
CSH2_k127_584360_2 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000001421 70.0
CSH2_k127_5848933_0 Carboxypeptidase regulatory-like domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0012505,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.00000001374 66.0
CSH2_k127_5848933_1 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.00008753 56.0
CSH2_k127_5862148_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 530.0
CSH2_k127_5862148_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000003598 102.0
CSH2_k127_5864813_0 Putative small multi-drug export protein - - - 0.0000000000000000000000006718 109.0
CSH2_k127_5864813_1 Membrane protein of unknown function DUF63 - - - 0.00000000000000000000003275 102.0
CSH2_k127_5864813_2 ATP-dependent DNA helicase (RecQ) K03654 - 3.6.4.12 0.0000001487 61.0
CSH2_k127_5865431_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 516.0
CSH2_k127_5865431_1 Conserved repeat domain - - - 0.0003031 53.0
CSH2_k127_5865850_0 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0009458 48.0
CSH2_k127_5868585_0 PFAM TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000535 269.0
CSH2_k127_5868585_1 Met-10+ like-protein K07055 - 2.5.1.114 0.00000000000000000000000000000000000000000000005015 186.0
CSH2_k127_5868585_2 Cation transport protein K03498 - - 0.000000000000000000001321 104.0
CSH2_k127_5877718_0 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 296.0
CSH2_k127_5877718_1 Flavin containing amine oxidoreductase K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001271 281.0
CSH2_k127_5877718_2 4-Hydroxyphenylpyruvate dioxygenase - - - 0.0000000000000000000000000000000000000000000003018 174.0
CSH2_k127_5877718_3 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000003221 151.0
CSH2_k127_5883933_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 2.599e-302 944.0
CSH2_k127_5885631_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 386.0
CSH2_k127_5885631_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000007024 63.0
CSH2_k127_5900356_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 347.0
CSH2_k127_5900356_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000003664 220.0
CSH2_k127_5902201_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.218e-208 659.0
CSH2_k127_5902201_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000003651 236.0
CSH2_k127_5902201_2 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000007064 183.0
CSH2_k127_5902201_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000006008 128.0
CSH2_k127_5902201_4 Uncharacterized ArCR, COG1888 K09732 - - 0.000000000000000000000000001806 114.0
CSH2_k127_5902201_5 thiolester hydrolase activity - - - 0.0000003871 61.0
CSH2_k127_5902201_6 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.000001245 60.0
CSH2_k127_5904659_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000003552 274.0
CSH2_k127_5904659_1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000002259 241.0
CSH2_k127_5904659_10 The GLUG motif - - - 0.0000000001177 65.0
CSH2_k127_5904659_11 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000001218 66.0
CSH2_k127_5904659_12 - - - - 0.000008044 52.0
CSH2_k127_5904659_2 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000008216 227.0
CSH2_k127_5904659_3 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000000008359 196.0
CSH2_k127_5904659_4 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.000000000000000000000000000000000000000005834 156.0
CSH2_k127_5904659_5 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000002034 155.0
CSH2_k127_5904659_6 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000002831 112.0
CSH2_k127_5904659_7 Protein of unknown function DUF99 K09120 - - 0.000000000000000000000003213 109.0
CSH2_k127_5904659_8 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000005006 91.0
CSH2_k127_5904659_9 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000002297 83.0
CSH2_k127_5907517_0 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.0000000000000000000000000000000000003916 147.0
CSH2_k127_5907517_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000003389 121.0
CSH2_k127_5907517_2 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000112 78.0
CSH2_k127_5912588_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 591.0
CSH2_k127_5912588_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008019 270.0
CSH2_k127_5915833_0 metallocarboxypeptidase activity K05996 - 3.4.17.18 0.000000000000000000000000000000000000000000000000000002469 211.0
CSH2_k127_5922108_0 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 9.82e-198 628.0
CSH2_k127_5922108_1 Thioredoxin reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 306.0
CSH2_k127_5922108_2 metal-dependent phosphohydrolase, HD sub domain K03698,K12070 - - 0.000000000000000000000000000000000000000000000000000000000003006 214.0
CSH2_k127_5922108_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000361 215.0
CSH2_k127_5922108_4 Fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000001581 93.0
CSH2_k127_5922108_5 Zn_pept K07752 - 3.4.17.22 0.0000004067 64.0
CSH2_k127_5926699_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 449.0
CSH2_k127_5926699_1 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000002686 109.0
CSH2_k127_5927170_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 391.0
CSH2_k127_5932337_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 420.0
CSH2_k127_5932337_1 ATP-dependent peptidase activity K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 412.0
CSH2_k127_5932337_2 ArsR transcriptional regulator - - - 0.000001351 52.0
CSH2_k127_5936798_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 552.0
CSH2_k127_5937946_0 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 304.0
CSH2_k127_5937946_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone - - - 0.000000000000000000001415 100.0
CSH2_k127_5937946_2 - - - - 0.0000000002398 64.0
CSH2_k127_5937946_3 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000419 63.0
CSH2_k127_5953596_0 TIGRFAM RNA methyltransferase, TrmH family, group 1 - - - 0.00000000000000000000001102 106.0
CSH2_k127_5953596_1 Domain of unknown function DUF11 - - - 0.00000002576 66.0
CSH2_k127_5957087_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000008428 171.0
CSH2_k127_5957087_1 - - - - 0.0001621 46.0
CSH2_k127_5971666_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008658 246.0
CSH2_k127_5971666_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000008509 221.0
CSH2_k127_5971666_2 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000006158 135.0
CSH2_k127_5972932_0 PFAM ATP-NAD AcoX kinase - - - 0.0000000000000000000006735 97.0
CSH2_k127_5972932_1 Immunoglobulin like - - - 0.00008929 55.0
CSH2_k127_5982306_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000001525 143.0
CSH2_k127_5982306_1 Belongs to the peptidase S8 family K17734 - - 0.00000000000002926 85.0
CSH2_k127_5990954_0 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003253 233.0
CSH2_k127_5990954_1 Caspase domain - - - 0.00000000000000000000000000002412 128.0
CSH2_k127_5998932_0 Domain of unknown function (DUF4350) - - - 0.000000000000000001235 94.0
CSH2_k127_6026790_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 5.11e-201 633.0
CSH2_k127_6035647_0 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000000000000000004912 129.0
CSH2_k127_6035647_1 Maf-like protein K06287 - - 0.00000000000000000000000005545 115.0
CSH2_k127_6035647_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000001101 63.0
CSH2_k127_6044076_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 295.0
CSH2_k127_6044076_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.000000000000000000000000000000000000000000000000000000000257 209.0
CSH2_k127_6044076_2 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000004324 179.0
CSH2_k127_6044076_3 Transcriptional regulator, XRE family K03627 - - 0.000000000000000000001243 100.0
CSH2_k127_6059343_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 401.0
CSH2_k127_6059343_1 PFAM UspA domain protein - - - 0.00000000000000000004055 95.0
CSH2_k127_6086527_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 321.0
CSH2_k127_6120018_0 Fungalysin metallopeptidase (M36) - - - 0.00000001252 68.0
CSH2_k127_6120018_1 PFAM PKD domain containing protein - - - 0.00008631 55.0
CSH2_k127_6129269_0 aconitate hydratase K01681 - 4.2.1.3 2.128e-289 900.0
CSH2_k127_6129269_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000001273 167.0
CSH2_k127_6129269_2 COG1522 Transcriptional regulators - - - 0.0000000000000004077 91.0
CSH2_k127_6129269_3 Citrate lyase acyl carrier protein K01646 - - 0.00000005643 58.0
CSH2_k127_6130317_0 Phosphoheptose isomerase K03271 - 5.3.1.28 0.000000000000000000000000000000000005501 143.0
CSH2_k127_6130317_1 Belongs to the peptidase S8 family K20276 - - 0.0000000000001468 82.0
CSH2_k127_6139314_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000001829 153.0
CSH2_k127_6139314_1 domain, Protein - - - 0.000000000000002331 91.0
CSH2_k127_6139314_2 - - - - 0.0001259 47.0
CSH2_k127_6146371_0 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000001022 203.0
CSH2_k127_6146371_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000001215 175.0
CSH2_k127_6146371_2 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000000366 159.0
CSH2_k127_6146371_3 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000505 61.0
CSH2_k127_6148376_0 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.00000000000000000000000000000002443 143.0
CSH2_k127_6148376_1 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000608 61.0
CSH2_k127_6150352_0 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000007396 112.0
CSH2_k127_6163646_0 alpha/beta hydrolase fold K01563,K22318 - 3.8.1.5 0.00000000000000000000000000000006841 128.0
CSH2_k127_6163646_1 domain, Protein - - - 0.00006005 55.0
CSH2_k127_6164619_0 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000003453 239.0
CSH2_k127_6164619_1 ERCC4 domain K10896 - - 0.000000000000000000000000000000000000000000000000000009933 200.0
CSH2_k127_6164619_2 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000001375 160.0
CSH2_k127_6168492_0 lysyl-tRNA aminoacylation K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 477.0
CSH2_k127_6170404_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone - - - 0.0000000000000000000000000000000000000000002811 182.0
CSH2_k127_6172254_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.000000000000000000000000000000000000000000000001013 186.0
CSH2_k127_6172254_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000001103 168.0
CSH2_k127_6172254_2 PFAM helix-turn-helix HxlR type - - - 0.0000000000000000000000000000000001147 136.0
CSH2_k127_6172296_0 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000000000000000001103 227.0
CSH2_k127_6172296_1 PFAM Type II secretion system protein E K07332 - - 0.00000000000000000000000000000000000000000000003604 173.0
CSH2_k127_6172296_2 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000002091 155.0
CSH2_k127_6172296_3 domain, Protein - - - 0.000000000000000000000000000000002742 143.0
CSH2_k127_6172296_4 Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000000000000001791 132.0
CSH2_k127_6172296_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000002799 130.0
CSH2_k127_6184254_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000003989 195.0
CSH2_k127_6184254_1 Protein of unknown function (DUF1616) - - - 0.00000000000000000000000007388 118.0
CSH2_k127_6184254_2 Protein of unknown function DUF58 - - - 0.00000000000000000000005613 115.0
CSH2_k127_6184640_0 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000000000000000000007446 196.0
CSH2_k127_6187777_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 385.0
CSH2_k127_6187777_1 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 296.0
CSH2_k127_6194731_0 spore germination K03298 - - 0.00000000000000000000000000000000000000000000000000000000000658 219.0
CSH2_k127_6194731_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000258 151.0
CSH2_k127_6194731_2 Belongs to the UPF0178 family - - - 0.000000001287 59.0
CSH2_k127_6242428_0 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000000000000602 180.0
CSH2_k127_6242428_1 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.00000000000000000001843 93.0
CSH2_k127_6242428_2 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000001135 92.0
CSH2_k127_6256484_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002701 278.0
CSH2_k127_6256484_1 von willebrand factor, type A K12549 - - 0.00000004974 65.0
CSH2_k127_6266067_0 Flavin containing amine oxidoreductase K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 367.0
CSH2_k127_6266067_1 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 287.0
CSH2_k127_6274373_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004371 243.0
CSH2_k127_6274373_1 deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000005772 224.0
CSH2_k127_6274373_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000001432 60.0
CSH2_k127_6276540_0 ATPase involved in DNA repair K03546 - - 0.00000000000000000003855 105.0
CSH2_k127_6277509_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000002183 129.0
CSH2_k127_6278840_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1021.0
CSH2_k127_6278840_1 Na H ion antiporter subunit K05569 - - 0.0000000000000000000000000000000000001542 147.0
CSH2_k127_6301582_0 Periplasmic copper-binding protein (NosD) - - - 0.00003173 55.0
CSH2_k127_6314760_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000006111 120.0
CSH2_k127_6344227_0 acetyltransferase - - - 0.0000000000000000000001406 103.0
CSH2_k127_6344227_1 DNA methylase K00590 - 2.1.1.113 0.00000000000000000004941 90.0
CSH2_k127_6344227_2 Fibronectin type 3 domain K22350 - 1.16.3.3 0.00000000001446 74.0
CSH2_k127_6370695_0 AAA domain K01338 - 3.4.21.53 0.000000000000000000000000000000000005956 141.0
CSH2_k127_6370695_1 archaeal coiled-coil protein - - - 0.000000000003364 77.0
CSH2_k127_6397556_0 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000001462 235.0
CSH2_k127_6397556_1 calcium ion binding - - - 0.0000003182 60.0
CSH2_k127_6397556_2 Belongs to the UPF0248 family K09715 - - 0.00008185 48.0
CSH2_k127_6397556_3 Protein of unknown function (DUF3068) - - - 0.0003476 52.0
CSH2_k127_6411015_0 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000006759 221.0
CSH2_k127_6411015_1 Thioredoxin K03671 - - 0.000000000000000000000000000000000003325 142.0
CSH2_k127_6411015_2 pyrroloquinoline quinone biosynthetic process - - - 0.00000000000000000000000000000000005557 139.0
CSH2_k127_6411015_3 Snare associated golgi protein - - - 0.00000000000224 75.0
CSH2_k127_6422464_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 498.0
CSH2_k127_6422464_1 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.0000000000000000000000000000000000000007592 163.0
CSH2_k127_6422464_2 Fibronectin type III domain protein - - - 0.000000000000000000003682 109.0
CSH2_k127_6427316_0 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000001492 169.0
CSH2_k127_6431073_0 AAA-like domain K06915 - - 0.00000000000000000000003812 111.0
CSH2_k127_6433860_0 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000006013 208.0
CSH2_k127_6433860_1 - - - - 0.0000000000003564 83.0
CSH2_k127_6433860_2 - - - - 0.00001482 52.0
CSH2_k127_649873_0 FG-GAP repeat - - - 0.00000000001098 78.0
CSH2_k127_6519797_0 regulator of chromosome condensation, RCC1 K20276 - - 0.00000000004295 77.0
CSH2_k127_6519797_1 - - - - 0.0002838 55.0
CSH2_k127_6520362_0 class II (D K and N) K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 422.0
CSH2_k127_6520362_1 cellulase activity K20276 - - 0.00000000002805 75.0
CSH2_k127_6527842_0 FtsX-like permease family - - - 0.000000000000000000000000001905 130.0
CSH2_k127_6527842_1 PKS_KR - - - 0.0000000000000000000000001593 122.0
CSH2_k127_6527842_2 polyketide synthase - - - 0.000000000000000004433 98.0
CSH2_k127_6527842_3 FtsX-like permease family - - - 0.00000000000001104 84.0
CSH2_k127_6547671_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000002189 125.0
CSH2_k127_6547671_1 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.0000000000000000009152 99.0
CSH2_k127_6582490_0 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000002644 236.0
CSH2_k127_6582490_1 Q COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000002477 67.0
CSH2_k127_6582490_2 MacB-like periplasmic core domain K02003,K02004 - - 0.0000004367 57.0
CSH2_k127_6586898_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000005165 218.0
CSH2_k127_6586898_1 Cupin domain - - - 0.00000009213 59.0
CSH2_k127_6586898_2 Domain of unknown function (DUF1844) - - - 0.0005006 48.0
CSH2_k127_6586898_3 Amino acid permease - - - 0.0007365 43.0
CSH2_k127_6595196_0 Ferrous iron transport protein B K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 507.0
CSH2_k127_6595196_1 Isochorismatase family - - - 0.000000000000000000000000000000000000002318 153.0
CSH2_k127_6595196_2 S-layer protein - - - 0.000000000000001984 90.0
CSH2_k127_6605746_0 domain protein - - - 0.0000000000001751 81.0
CSH2_k127_6605746_1 bacterial-type flagellum-dependent cell motility K01119,K06113,K12685,K20276 - 3.1.3.6,3.1.4.16,3.2.1.99 0.0001766 55.0
CSH2_k127_6633879_0 by modhmm - - - 0.000007018 59.0
CSH2_k127_663520_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.0 1042.0
CSH2_k127_663520_1 Cellulose binding domain - - - 0.000007577 59.0
CSH2_k127_663520_2 Chemotaxis protein cheY K03413 - - 0.00006689 49.0
CSH2_k127_6637569_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001054 280.0
CSH2_k127_6637569_1 Belongs to the BI1 family K06890,K19416 - - 0.0000000000000000000000002383 117.0
CSH2_k127_6665716_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 431.0
CSH2_k127_6665716_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000001596 124.0
CSH2_k127_6675204_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000003227 187.0
CSH2_k127_6675204_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000007517 181.0
CSH2_k127_6675204_2 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.0000000000000000000000000000002695 124.0
CSH2_k127_6688847_0 Helix-hairpin-helix motif K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002933 248.0
CSH2_k127_6688847_1 DNA-directed RNA polymerase subunit F K03051 - 2.7.7.6 0.0000000001006 68.0
CSH2_k127_6702677_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 336.0
CSH2_k127_6702677_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000001788 134.0
CSH2_k127_672256_0 MMPL family - - - 0.00000000000000000000000000000006804 139.0
CSH2_k127_6726672_0 E1-E2 ATPase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 506.0
CSH2_k127_6726672_1 YHS domain - - - 0.0000000000000000403 82.0
CSH2_k127_6727801_0 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 314.0
CSH2_k127_6727801_1 Oxidoreductase family, C-terminal alpha/beta domain K13016 - 1.1.1.335 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 296.0
CSH2_k127_6727801_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000117 168.0
CSH2_k127_6727801_3 Bacterial transferase hexapeptide K13018 - 2.3.1.201 0.0000000000000000002882 89.0
CSH2_k127_6727801_4 Putative Phosphatase - - - 0.000000000001952 71.0
CSH2_k127_6727801_5 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000001185 69.0
CSH2_k127_6731083_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.348e-244 768.0
CSH2_k127_6731083_1 Response regulator receiver domain - - - 0.0000000000000000000473 94.0
CSH2_k127_6731083_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000002695 68.0
CSH2_k127_6741120_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 385.0
CSH2_k127_6741120_1 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000002621 162.0
CSH2_k127_6741120_2 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000001309 154.0
CSH2_k127_6741120_3 isomerase K01808 GO:0003674,GO:0003824,GO:0004751,GO:0016853,GO:0016860,GO:0016861 5.3.1.6 0.0000000000000000000000000000000000001229 147.0
CSH2_k127_6741164_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006207 295.0
CSH2_k127_6744462_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 327.0
CSH2_k127_6748522_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 444.0
CSH2_k127_6748522_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 362.0
CSH2_k127_6748522_2 - - - - 0.000006298 53.0
CSH2_k127_675714_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 361.0
CSH2_k127_675714_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007138 266.0
CSH2_k127_675714_2 Peptidase family S51 - - - 0.0000000000000000000000000000000000000000000000002169 183.0
CSH2_k127_6759858_0 Beta-Casp domain K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 415.0
CSH2_k127_6759858_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000000001001 101.0
CSH2_k127_6759858_2 serine threonine protein kinase - - - 0.0000000000000167 85.0
CSH2_k127_682743_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 549.0
CSH2_k127_700907_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 591.0
CSH2_k127_700907_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000138 107.0
CSH2_k127_710311_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 391.0
CSH2_k127_710311_1 PAS domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 354.0
CSH2_k127_710311_2 PFAM LemA family protein K03744 - - 0.0005623 44.0
CSH2_k127_737375_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 320.0
CSH2_k127_737375_1 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000000000000000000217 179.0
CSH2_k127_737375_2 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000000000000000000000000000000000001435 148.0
CSH2_k127_737375_3 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity) K01170 - 4.6.1.16 0.000000000000000000000000000000002796 142.0
CSH2_k127_737375_4 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001114 96.0
CSH2_k127_737375_5 Belongs to the PDCD5 family K06875 - - 0.0000000000000000006181 90.0
CSH2_k127_737375_6 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.000000004475 63.0
CSH2_k127_766315_0 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000000000000000000006196 174.0
CSH2_k127_766315_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000001833 173.0
CSH2_k127_766315_2 cellulose binding - - - 0.000008624 60.0
CSH2_k127_80209_0 transcription activator, effector binding - - - 0.0000000000000000000000000000000000000000000005358 170.0
CSH2_k127_80209_1 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000001147 138.0
CSH2_k127_80209_2 Hexapeptide repeat of succinyl-transferase K00661 - 2.3.1.79 0.000000000000000000000000000005124 125.0
CSH2_k127_80209_3 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0007365 43.0
CSH2_k127_838246_0 Radical SAM - - - 0.00000000000000000000000003978 113.0
CSH2_k127_838246_1 exo-alpha-(2->6)-sialidase activity - - - 0.0008979 52.0
CSH2_k127_847155_0 COG1520 FOG WD40-like repeat - - - 0.0000000000001384 86.0
CSH2_k127_857711_0 Bacterial transcriptional activator domain - - - 0.00000000000000000000001063 118.0
CSH2_k127_857711_1 - - - - 0.00000000000000000003281 92.0
CSH2_k127_857711_2 AAA ATPase domain - - - 0.0005175 53.0
CSH2_k127_857711_3 chlorophyll binding - - - 0.0008891 50.0
CSH2_k127_864377_0 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 560.0
CSH2_k127_872176_0 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 295.0
CSH2_k127_872176_1 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001931 256.0
CSH2_k127_872176_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000002151 206.0
CSH2_k127_872176_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000009334 137.0
CSH2_k127_872176_4 Fibronectin type III domain - - - 0.0000006709 55.0
CSH2_k127_880831_0 Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde K05829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 382.0
CSH2_k127_880831_1 PFAM ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp K05827 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 323.0
CSH2_k127_880831_2 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 - - 0.00000000000000000000000000000000003095 138.0
CSH2_k127_880831_3 TIGRFAM Lysine biosynthesis protein LysW K05826 - - 0.000000000004418 68.0
CSH2_k127_884423_0 histidyl-tRNA aminoacylation K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.00000000000000000000000000004855 124.0
CSH2_k127_884423_1 TPR repeat-containing protein - - - 0.000000008899 69.0
CSH2_k127_897891_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.4.2.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 484.0
CSH2_k127_897891_1 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002095 276.0
CSH2_k127_897891_2 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000006597 172.0
CSH2_k127_89818_0 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000001096 192.0
CSH2_k127_89818_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000008434 89.0
CSH2_k127_915590_0 Pfam:DUF137 K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000856 271.0
CSH2_k127_915590_1 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000001007 225.0
CSH2_k127_915590_2 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000267 126.0
CSH2_k127_915590_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000117 119.0
CSH2_k127_915590_4 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000004012 100.0
CSH2_k127_915590_5 RNA binding K07581 - - 0.00000000000003183 79.0
CSH2_k127_922379_0 transcriptional K03892 - - 0.0009538 45.0
CSH2_k127_923772_0 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 346.0
CSH2_k127_923772_1 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000005326 160.0
CSH2_k127_923772_2 Methyltransferase type 11 - - - 0.0000000000000000000001998 107.0
CSH2_k127_923772_3 PFAM membrane-bound metal-dependent hydrolase K07038 - - 0.0000000000000000000003111 102.0
CSH2_k127_923772_4 Integral membrane protein DUF106 - - - 0.00000000000000001128 93.0
CSH2_k127_923772_5 NYN domain - - - 0.00000000414 64.0
CSH2_k127_929102_0 KH domain protein K06961 - - 0.0000000000000000000000000000000000000126 153.0
CSH2_k127_929102_1 PFAM Major Facilitator Superfamily K19576 - - 0.000000000000000000000007369 108.0
CSH2_k127_929102_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000001922 89.0
CSH2_k127_966100_0 Serine protease with a broad substrate specificity K17734 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000002427 163.0
CSH2_k127_966657_0 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 388.0
CSH2_k127_966657_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 373.0
CSH2_k127_966657_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000002162 78.0
CSH2_k127_969903_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 370.0
CSH2_k127_969903_1 Thymidylate synthase complementing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001803 289.0
CSH2_k127_969903_2 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000001606 81.0
CSH2_k127_969903_3 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.00001153 49.0
CSH2_k127_99141_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000001901 243.0
CSH2_k127_99141_1 Protein involved in outer membrane biogenesis - - - 0.00000000000000000005053 107.0
CSH2_k127_99141_2 PFAM Fibronectin type III domain - - - 0.0000002432 65.0
CSH2_k127_994527_0 Isocitrate/isopropylmalate dehydrogenase K00052,K10978 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85,1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 469.0
CSH2_k127_994527_1 nuclease activity K18828 - - 0.00000000000001259 78.0
CSH2_k127_994527_2 Zgc 73340 K15444 GO:0000049,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008198,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016491,GO:0016705,GO:0016706,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.229 0.000002197 54.0
CSH2_k127_994527_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00007549 48.0
CSH2_k127_994527_4 Putative antitoxin - - - 0.0004153 49.0