Overview

ID MAG00615
Name CSH2_bin.32
Sample SMP0014
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order JAJSAE01
Family
Genus
Species
Assembly information
Completeness (%) 72.75
Contamination (%) 0.49
GC content (%) 59.0
N50 (bp) 3,368
Genome size (bp) 1,323,931

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1230

Gene name Description KEGG GOs EC E-value Score Sequence
CSH2_k127_1005235_0 - - - - 0.00000000000000000000000000000000000000000565 166.0
CSH2_k127_1005235_1 - - - - 0.0000000000000007034 84.0
CSH2_k127_1013307_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000001353 243.0
CSH2_k127_1013307_1 PFAM Glycosyl transferase family 4 K01001 - 2.7.8.15 0.00000000000000000000000000000000000000000000000000000001442 210.0
CSH2_k127_1013307_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000002872 68.0
CSH2_k127_1013307_3 PFAM PUA domain containing protein K07398 - - 0.00000111 51.0
CSH2_k127_1016500_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 455.0
CSH2_k127_1016500_1 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000008979 121.0
CSH2_k127_1017525_0 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000008499 95.0
CSH2_k127_1017525_1 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000239 81.0
CSH2_k127_1028785_0 pfkB family carbohydrate kinase - - - 0.00000000000000000000003355 111.0
CSH2_k127_1028785_1 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000001093 90.0
CSH2_k127_1028785_2 helix_turn_helix ASNC type - - - 0.0000000009432 70.0
CSH2_k127_1030834_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002949 265.0
CSH2_k127_1030834_1 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000002118 73.0
CSH2_k127_1041452_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 513.0
CSH2_k127_1041452_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 373.0
CSH2_k127_1042516_0 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000138 284.0
CSH2_k127_1042516_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000001761 137.0
CSH2_k127_1042516_2 aminopeptidase activity K05994 - 3.4.11.10 0.0000000000000000000000005106 117.0
CSH2_k127_1042516_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 0.000000001622 61.0
CSH2_k127_1048333_0 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000004714 196.0
CSH2_k127_1048333_1 TOPRIM - - - 0.0000000000000000004082 93.0
CSH2_k127_1048333_2 Pfam:KaiC - - - 0.0001211 45.0
CSH2_k127_1055959_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 454.0
CSH2_k127_1055959_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000007481 224.0
CSH2_k127_1067102_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 351.0
CSH2_k127_1067102_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001261 276.0
CSH2_k127_1067102_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000005819 149.0
CSH2_k127_1089408_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 1.631e-241 756.0
CSH2_k127_1089408_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 433.0
CSH2_k127_1089408_2 COG1024 Enoyl-CoA hydratase carnithine racemase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000004244 235.0
CSH2_k127_1089408_3 PhoU domain - - - 0.000000000000000000000000000000000000000000000000000000000001517 220.0
CSH2_k127_1089408_4 - - - - 0.0000000000000000000002693 97.0
CSH2_k127_1106054_0 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 434.0
CSH2_k127_1106054_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 301.0
CSH2_k127_1106054_2 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000492 223.0
CSH2_k127_1106054_3 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000000009195 154.0
CSH2_k127_1124661_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 430.0
CSH2_k127_1124661_1 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000335 221.0
CSH2_k127_1124661_2 PIN domain - - - 0.0000000001891 61.0
CSH2_k127_1136298_0 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000000000000000000000624 226.0
CSH2_k127_1153400_0 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000004424 123.0
CSH2_k127_1153400_1 DsrE/DsrF-like family K07235 - - 0.0000000000000000001736 94.0
CSH2_k127_1153400_2 Belongs to the sulfur carrier protein TusA family - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000001077 73.0
CSH2_k127_1153400_3 DsrE/DsrF-like family K06039 - - 0.0001912 48.0
CSH2_k127_1160382_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 391.0
CSH2_k127_1160382_1 Membrane protein of unknown function DUF63 - - - 0.0000000000000002098 91.0
CSH2_k127_1162040_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000006759 188.0
CSH2_k127_1162040_1 Beta-Casp domain K07577 - - 0.0000000000000000000000000005418 118.0
CSH2_k127_1162040_2 von Willebrand factor type A domain K07114 - - 0.00000004098 66.0
CSH2_k127_1234769_0 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000001229 143.0
CSH2_k127_1234769_1 cellulose binding - - - 0.000000000000000000000000000000864 133.0
CSH2_k127_1234769_2 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000004841 124.0
CSH2_k127_1240388_0 histone deacetylase K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001786 266.0
CSH2_k127_1240388_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000006931 63.0
CSH2_k127_1241917_0 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 304.0
CSH2_k127_1241917_1 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000005052 117.0
CSH2_k127_1279920_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 386.0
CSH2_k127_1291947_0 Glycosyl transferase family 4 K01001 - 2.7.8.15 0.0000000000000000000000000000001333 137.0
CSH2_k127_1298061_0 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 315.0
CSH2_k127_1298061_1 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000002173 258.0
CSH2_k127_1298061_2 Right handed beta helix region - - - 0.000000000000000000000000000008986 134.0
CSH2_k127_1306166_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.197e-249 780.0
CSH2_k127_1306166_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 472.0
CSH2_k127_1306166_2 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 368.0
CSH2_k127_1306166_3 PUA domain containing protein K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000009125 169.0
CSH2_k127_1306166_4 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000002181 156.0
CSH2_k127_1306166_5 Integral membrane protein DUF106 - - - 0.0000000000000000000000000003845 124.0
CSH2_k127_1306166_6 AAA domain - - - 0.0000000000000000002753 101.0
CSH2_k127_1306166_7 Acetyltransferase (GNAT) domain - - - 0.00001675 56.0
CSH2_k127_1306166_8 - - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - 0.0001277 49.0
CSH2_k127_134338_0 - - - - 0.00000000000000000000000000003001 130.0
CSH2_k127_134338_1 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.0000000007156 62.0
CSH2_k127_1358187_0 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000001751 251.0
CSH2_k127_1358187_1 SIS domain K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000289 161.0
CSH2_k127_1358187_2 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.00002618 48.0
CSH2_k127_13661_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 8.911e-210 662.0
CSH2_k127_13661_1 PFAM Flavodoxin nitric oxide synthase - - - 0.0000000000000000000000000000000000000000000004097 169.0
CSH2_k127_1384960_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 357.0
CSH2_k127_1384960_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 347.0
CSH2_k127_1384960_2 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.000000000000000000000000000000000000000000000001689 182.0
CSH2_k127_1384960_3 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.00000000000000000000000000000000000000006718 154.0
CSH2_k127_1398968_0 TIGRFAM oligoendopeptidase, M3 family K08602 - - 0.000000000000000000000000000000000000000000103 175.0
CSH2_k127_1398968_1 S-layer homology domain K01181,K20276 - 3.2.1.8 0.00000000000000000000000000001522 137.0
CSH2_k127_1398968_2 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000001396 79.0
CSH2_k127_1404443_0 Amb_all K01728 - 4.2.2.2 0.00000000000000000000000000000005683 141.0
CSH2_k127_1404443_1 AAA-like domain K06915 - - 0.0000000008054 63.0
CSH2_k127_1417270_0 RecT family - - - 0.000000000000000000000000000000000000000000000000000000000000292 217.0
CSH2_k127_1417270_1 Belongs to the helicase family. UvrD subfamily - - - 0.0000000008937 66.0
CSH2_k127_1425856_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 417.0
CSH2_k127_1425856_1 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 302.0
CSH2_k127_1447215_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 287.0
CSH2_k127_1447215_1 Lipoate-protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000001512 246.0
CSH2_k127_1447215_2 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000000000000000000000000000000000000000000000000000006641 209.0
CSH2_k127_1447215_3 PFAM Radical SAM superfamily K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000001754 188.0
CSH2_k127_1447215_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000001448 175.0
CSH2_k127_1447215_5 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.00001562 57.0
CSH2_k127_1461511_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 593.0
CSH2_k127_1461511_1 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.00000000000000000000000000000000000000000000000000000000006306 211.0
CSH2_k127_1461511_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.000000000000003214 79.0
CSH2_k127_1461511_3 membrane - - - 0.0000000000000673 85.0
CSH2_k127_1461761_0 Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 362.0
CSH2_k127_1461761_1 Belongs to the mandelate racemase muconate lactonizing enzyme family K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000002802 232.0
CSH2_k127_1461761_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000002307 152.0
CSH2_k127_1461761_3 Iron-sulfur cluster-binding domain - - - 0.00000000003089 70.0
CSH2_k127_1468112_0 Nucleotidyltransferase domain - - - 0.00000000000000000001728 99.0
CSH2_k127_1468112_1 - - - - 0.00000000000009718 77.0
CSH2_k127_1468112_2 HELICc2 - - - 0.000355 46.0
CSH2_k127_1486756_0 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.000000000000000000000000000000000000000000001019 172.0
CSH2_k127_1486756_1 DnaB-like helicase C terminal domain - - - 0.0000000000000000000000000000000000004604 149.0
CSH2_k127_1486756_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000009318 134.0
CSH2_k127_1486756_3 Glycogen debranching enzyme - - - 0.00000000000000002482 91.0
CSH2_k127_1500367_0 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.0000000000008957 82.0
CSH2_k127_1511701_0 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 307.0
CSH2_k127_1511701_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000003238 147.0
CSH2_k127_1522257_0 Citrate transporter - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000002551 145.0
CSH2_k127_1522257_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000001886 72.0
CSH2_k127_1533197_0 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005381 281.0
CSH2_k127_1533197_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000002182 98.0
CSH2_k127_1533197_2 FR47-like protein - - - 0.0001865 51.0
CSH2_k127_1535105_0 PFAM PKD domain containing protein - - - 0.0000003891 63.0
CSH2_k127_1537524_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 342.0
CSH2_k127_1537524_1 LemA family K03744 - - 0.0000000000000000000000000000000000000001593 158.0
CSH2_k127_1537524_2 TPM domain K06872 - - 0.0000000000000000000000009157 109.0
CSH2_k127_1540766_0 Cellulose 1,4-beta-cellobiosidase - - - 0.00000000000000000000003624 114.0
CSH2_k127_1540766_1 Protein of unknown function (DUF3494) - - - 0.0001886 55.0
CSH2_k127_1579403_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 394.0
CSH2_k127_1601255_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 386.0
CSH2_k127_1601255_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001363 264.0
CSH2_k127_1601255_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000306 112.0
CSH2_k127_1601255_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000005979 84.0
CSH2_k127_1601255_4 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00003723 46.0
CSH2_k127_1604257_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 522.0
CSH2_k127_1604257_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 310.0
CSH2_k127_1616427_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 317.0
CSH2_k127_1616427_1 N-6 DNA Methylase K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.00000000000000000000000000000000000000000000007635 181.0
CSH2_k127_1616427_2 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.00000000000000000000000000000000000000000009305 173.0
CSH2_k127_1616427_3 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000004766 93.0
CSH2_k127_1629965_0 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001902 245.0
CSH2_k127_1629965_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000007553 124.0
CSH2_k127_1629965_2 Glycosyl transferases group 1 K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.00000003391 64.0
CSH2_k127_1633030_0 integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 330.0
CSH2_k127_1633030_1 Subtilase family K01342 - 3.4.21.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008544 279.0
CSH2_k127_1633030_2 von Willebrand factor, type A K07114 - - 0.000004404 50.0
CSH2_k127_1664172_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 507.0
CSH2_k127_1664172_1 aldo keto reductase family K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 463.0
CSH2_k127_166784_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 537.0
CSH2_k127_166784_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000001207 268.0
CSH2_k127_166784_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000009986 231.0
CSH2_k127_166784_3 Thioesterase superfamily K07107 - - 0.0000002997 55.0
CSH2_k127_1670270_0 - - - - 0.00000000000000000000000000000000145 137.0
CSH2_k127_1670270_1 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.0000000000000000000000000000008063 127.0
CSH2_k127_1670270_2 Pectate lyase K21606 - 3.2.1.202 0.0000007406 60.0
CSH2_k127_1670552_0 DnaB-like helicase C terminal domain - - - 0.0000000000000000000000000000000001155 147.0
CSH2_k127_1671625_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 509.0
CSH2_k127_1676527_0 FAD binding domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000125 220.0
CSH2_k127_1678868_0 Helix-turn-helix XRE-family like proteins K07731 - - 0.000000000000000000000000000000000000000000000000000000000002162 214.0
CSH2_k127_1678868_1 Glycosyltransferase Family 4 K13677 - 2.4.1.208 0.0000000000000001362 84.0
CSH2_k127_1678868_2 PAP2 superfamily - - - 0.000000003262 68.0
CSH2_k127_1680802_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001532 247.0
CSH2_k127_1680802_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000002422 161.0
CSH2_k127_1680802_2 Ribbon-helix-helix protein, copG family K07722 - - 0.00000000000000000007057 93.0
CSH2_k127_1716148_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000251 282.0
CSH2_k127_1716148_1 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000339 270.0
CSH2_k127_1716950_0 Type II/IV secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 424.0
CSH2_k127_1716950_1 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000000005125 231.0
CSH2_k127_1716950_2 Type II secretion system K07333 - - 0.00000000000000000000000000000000002257 138.0
CSH2_k127_1731440_0 GDP-mannose 4,6 dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000003897 134.0
CSH2_k127_1731440_1 ADP-glyceromanno-heptose 6-epimerase activity K00091,K01784,K12454 - 1.1.1.219,5.1.3.10,5.1.3.2 0.0002383 48.0
CSH2_k127_1767954_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 352.0
CSH2_k127_1767954_1 PP-loop family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003459 238.0
CSH2_k127_1814311_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.959e-195 632.0
CSH2_k127_1823489_0 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003198 251.0
CSH2_k127_1823489_1 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000000000000000000000000000000003042 152.0
CSH2_k127_1823489_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000001405 77.0
CSH2_k127_1828299_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 608.0
CSH2_k127_1828299_1 Fibronectin type III domain protein - - - 0.00000000000000000000000000000000000000000000000000000008276 218.0
CSH2_k127_1828299_2 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000004745 169.0
CSH2_k127_1828299_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000002908 157.0
CSH2_k127_1844971_0 TIGRFAM MIP family channel K02440,K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 296.0
CSH2_k127_1844971_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000001773 98.0
CSH2_k127_1844971_2 Protein of unknown function (DUF835) - - - 0.0009606 50.0
CSH2_k127_1904364_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000007931 229.0
CSH2_k127_1904364_1 CoA binding domain K06929 - - 0.0000000000000000000000000000000007662 146.0
CSH2_k127_1904364_2 Methyltransferase type 11 - - - 0.0000000000000001472 89.0
CSH2_k127_1922142_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 8.589e-219 687.0
CSH2_k127_1922142_1 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 432.0
CSH2_k127_1922142_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000001352 130.0
CSH2_k127_1923196_0 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000001561 144.0
CSH2_k127_1923196_1 PQQ enzyme repeat - - - 0.0000000000000002892 95.0
CSH2_k127_1923196_2 - - - - 0.00000284 54.0
CSH2_k127_1929539_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 303.0
CSH2_k127_1929539_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000002426 117.0
CSH2_k127_1929796_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.72e-306 958.0
CSH2_k127_1947519_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000002181 175.0
CSH2_k127_1950996_0 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1097.0
CSH2_k127_1950996_1 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.836e-275 879.0
CSH2_k127_1950996_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 347.0
CSH2_k127_1950996_3 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000462 146.0
CSH2_k127_1950996_4 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000000000000007636 130.0
CSH2_k127_1962562_0 Belongs to the peptidase S8 family - - - 0.00000000000000004931 95.0
CSH2_k127_1962562_1 PFAM PKD domain containing protein - - - 0.0001383 55.0
CSH2_k127_1986277_0 PFAM Acyl-CoA dehydrogenase K00248,K22430 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108,1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 435.0
CSH2_k127_1986277_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000006329 243.0
CSH2_k127_1986277_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000000000002703 217.0
CSH2_k127_1986277_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000001074 213.0
CSH2_k127_1986277_4 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000002642 204.0
CSH2_k127_1986277_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000001458 174.0
CSH2_k127_1986277_6 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000008379 141.0
CSH2_k127_1986277_7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.00000000000000000000000004133 108.0
CSH2_k127_1986277_8 archaeal Zn-finger protein - - - 0.00000000000000000004791 100.0
CSH2_k127_1986277_9 OmpA family K02557,K03286 - - 0.000000002747 69.0
CSH2_k127_2007652_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 562.0
CSH2_k127_2007652_1 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004887 288.0
CSH2_k127_2007652_2 Belongs to the 'phage' integrase family - - - 0.00002067 55.0
CSH2_k127_2014596_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 457.0
CSH2_k127_2014596_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.00000000000000000000000000000000000000000000000000000000000001484 218.0
CSH2_k127_2014596_2 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000003543 169.0
CSH2_k127_2015688_0 VWA / Hh protein intein-like - - - 0.000001087 61.0
CSH2_k127_2035501_0 TPR repeat-containing protein K07452 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003124 275.0
CSH2_k127_2035501_1 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000001051 244.0
CSH2_k127_2053828_0 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 309.0
CSH2_k127_2053828_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000001011 162.0
CSH2_k127_2053828_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000001205 126.0
CSH2_k127_2053828_3 PFAM TPR repeat-containing protein - - - 0.0000005898 53.0
CSH2_k127_2059842_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000009459 217.0
CSH2_k127_2059842_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000001587 213.0
CSH2_k127_2102627_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 375.0
CSH2_k127_2102627_1 Fibronectin type III domain - - - 0.00000000000000000000000000000009185 142.0
CSH2_k127_2115098_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000735 52.0
CSH2_k127_212873_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.348e-253 792.0
CSH2_k127_212873_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000703 83.0
CSH2_k127_2132872_0 Terminase RNaseH-like domain - - - 0.0000000000000000000000000000000000000000000000000000000002024 208.0
CSH2_k127_2132872_1 - - - - 0.0004343 52.0
CSH2_k127_2133823_0 Aminotransferase class-III K00821,K03918,K07250,K13524,K20428 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 407.0
CSH2_k127_2139297_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 414.0
CSH2_k127_2139297_1 Pyruvoyl-dependent arginine decarboxylase K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000006271 181.0
CSH2_k127_2139297_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000006654 166.0
CSH2_k127_2154856_0 Domain of unknown function DUF87 K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000646 242.0
CSH2_k127_2154856_1 NurA - - - 0.00000002034 66.0
CSH2_k127_2154856_2 CBS domain - - - 0.00000003783 59.0
CSH2_k127_2156563_0 DEAD/H associated K03724 - - 6.529e-310 986.0
CSH2_k127_2156563_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000004666 94.0
CSH2_k127_2165651_0 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 341.0
CSH2_k127_2165651_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000001811 75.0
CSH2_k127_2191303_0 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000214 190.0
CSH2_k127_2191303_1 domain protein - - - 0.00003847 54.0
CSH2_k127_2214943_0 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000000458 157.0
CSH2_k127_2214943_1 tetratricopeptide repeat - - - 0.00000000000001327 85.0
CSH2_k127_2217610_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 393.0
CSH2_k127_2217610_1 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002126 284.0
CSH2_k127_2217610_2 - - - - 0.00000000004885 76.0
CSH2_k127_2222756_0 Terminase RNaseH-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 425.0
CSH2_k127_2224154_0 hydrogenase large subunit K14126 - 1.8.98.5 7.926e-238 742.0
CSH2_k127_2224154_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.653e-233 738.0
CSH2_k127_2224154_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 424.0
CSH2_k127_2224154_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000001062 208.0
CSH2_k127_2224154_4 DNA-binding transcription factor activity - - - 0.000000000000000000000000005043 117.0
CSH2_k127_2241594_0 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 600.0
CSH2_k127_2241594_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000002216 128.0
CSH2_k127_224368_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 419.0
CSH2_k127_2280359_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 9.885e-215 679.0
CSH2_k127_2280359_1 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001551 266.0
CSH2_k127_2280359_2 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000008672 193.0
CSH2_k127_2280359_3 Predicted SAM-dependent RNA methyltransferase - - - 0.0000000000000000000000000002931 122.0
CSH2_k127_2280359_4 Tetratricopeptide repeat - - - 0.00001579 49.0
CSH2_k127_2305770_0 - - - - 0.00000000000000000000000004849 111.0
CSH2_k127_2305770_1 PFAM WD domain, G-beta repeat - - - 0.0003421 53.0
CSH2_k127_2309211_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 398.0
CSH2_k127_2309211_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000002455 279.0
CSH2_k127_2309211_2 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000002173 169.0
CSH2_k127_2384014_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 320.0
CSH2_k127_2395249_0 PUA domain containing protein K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000003187 222.0
CSH2_k127_2395249_1 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000001732 180.0
CSH2_k127_2395249_2 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000002662 147.0
CSH2_k127_2403417_0 Butirosin biosynthesis protein H, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000002567 208.0
CSH2_k127_2403417_1 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000009334 176.0
CSH2_k127_2403417_2 Belongs to the PDCD5 family K06875 - - 0.00000000000000000000007556 102.0
CSH2_k127_2403417_3 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000004677 78.0
CSH2_k127_2403417_4 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000002196 71.0
CSH2_k127_2403417_5 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001794 66.0
CSH2_k127_2417395_0 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 331.0
CSH2_k127_2417395_1 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000005732 51.0
CSH2_k127_2429622_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 335.0
CSH2_k127_2429622_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 317.0
CSH2_k127_2429622_2 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 290.0
CSH2_k127_2429622_3 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000002377 204.0
CSH2_k127_2429622_4 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000006025 153.0
CSH2_k127_2429622_5 PilT protein domain protein - - - 0.00000000000000000003115 98.0
CSH2_k127_2429622_6 protein conserved in archaea - - - 0.00000000493 66.0
CSH2_k127_2429622_7 - - - - 0.0002804 50.0
CSH2_k127_2439435_0 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 345.0
CSH2_k127_2439435_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000004026 239.0
CSH2_k127_2439435_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704,K16793 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.114,4.2.1.33,4.2.1.35 0.00004342 49.0
CSH2_k127_2448156_0 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 324.0
CSH2_k127_2448156_1 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000004727 209.0
CSH2_k127_2448156_2 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.000000000000000000000000000000000000000000000000000003204 201.0
CSH2_k127_2448156_3 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.0000000000000000000000000000000000000000000002669 183.0
CSH2_k127_2463685_0 Isochorismatase family - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009117,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019362,GO:0019637,GO:0019674,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901360,GO:1901564 - 0.000000000000000000000000000000000000002153 155.0
CSH2_k127_2463685_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000815 91.0
CSH2_k127_2463685_2 cation diffusion facilitator family transporter - - - 0.000000000009817 73.0
CSH2_k127_2471001_0 Beta-eliminating lyase K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009015 283.0
CSH2_k127_2471001_1 Oxidoreductase family, C-terminal alpha/beta domain K18855 - 1.1.1.374 0.0000000000000000000000000000000000000000000000000000000000009605 221.0
CSH2_k127_2471001_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000001343 92.0
CSH2_k127_2490812_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 449.0
CSH2_k127_2490812_1 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 359.0
CSH2_k127_2490812_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000005248 78.0
CSH2_k127_2513080_0 - - - - 0.0000000000000004537 87.0
CSH2_k127_2515411_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 332.0
CSH2_k127_2515411_1 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000001941 244.0
CSH2_k127_2515411_2 - - - - 0.0000000987 60.0
CSH2_k127_2520800_0 Peptidase family C25 K03546,K20074 - 3.1.3.16 0.0000008974 54.0
CSH2_k127_2520800_1 PFAM PKD domain containing protein - - - 0.0002613 55.0
CSH2_k127_2548474_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 299.0
CSH2_k127_2548474_1 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000002076 195.0
CSH2_k127_2548474_2 PFAM peptidase M55 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000186 195.0
CSH2_k127_2548474_3 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.000000000000000000000000000000000000000000000002385 179.0
CSH2_k127_2548474_4 palmitoyl-(protein) hydrolase activity - - - 0.000000000004209 78.0
CSH2_k127_2569530_0 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000009079 214.0
CSH2_k127_2569530_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.000000000000000000000000000000000001781 146.0
CSH2_k127_2569530_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000001076 103.0
CSH2_k127_2573904_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 526.0
CSH2_k127_2573904_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000001519 79.0
CSH2_k127_2575263_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 333.0
CSH2_k127_2575263_1 RNA-binding protein of the translin family K07477 - - 0.0000000000000000000000000000000000000000000000007872 184.0
CSH2_k127_2575263_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000007853 170.0
CSH2_k127_2575263_3 AMP binding K03322,K07076,K09944,K16263 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009268,GO:0009628,GO:0010035,GO:0010038,GO:0016020,GO:0042221,GO:0044464,GO:0046688,GO:0050896,GO:0071944,GO:0097501,GO:1990169 - 0.00000000000000000000000000007933 119.0
CSH2_k127_2586879_0 Galactose oxidase, central domain - - - 0.00000000000000000000008807 115.0
CSH2_k127_259927_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 496.0
CSH2_k127_259927_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 423.0
CSH2_k127_259927_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000001385 83.0
CSH2_k127_259927_11 response regulator, receiver - - - 0.0000000001872 66.0
CSH2_k127_259927_12 Protein of unknown function (DUF1614) - - - 0.00000003515 66.0
CSH2_k127_259927_13 Protein of unknown function (DUF835) - - - 0.00000003913 66.0
CSH2_k127_259927_14 (FHA) domain - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.0004539 51.0
CSH2_k127_259927_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 362.0
CSH2_k127_259927_3 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002413 286.0
CSH2_k127_259927_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000007839 266.0
CSH2_k127_259927_5 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000001405 205.0
CSH2_k127_259927_6 Helix-turn-helix XRE-family like proteins K03627 - - 0.00000000000000000000000000000852 124.0
CSH2_k127_259927_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000001548 118.0
CSH2_k127_259927_8 NUDIX domain - - - 0.0000000000000000000000002377 116.0
CSH2_k127_259927_9 snRNP Sm proteins K04796 - - 0.000000000000000002422 88.0
CSH2_k127_2611094_0 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 361.0
CSH2_k127_2611094_1 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000001693 240.0
CSH2_k127_2611094_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000002026 78.0
CSH2_k127_2612697_0 DEAD DEAH box helicase domain protein K10896 - - 0.00000000000000000000000000000000000000000000000000000004743 206.0
CSH2_k127_2616299_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001346 259.0
CSH2_k127_2616299_1 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000001015 166.0
CSH2_k127_2616299_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000003383 137.0
CSH2_k127_2622941_0 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 424.0
CSH2_k127_2622941_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 351.0
CSH2_k127_2622941_2 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 353.0
CSH2_k127_2622941_3 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 295.0
CSH2_k127_2622941_4 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.00000000000000000000000000003238 119.0
CSH2_k127_2622941_5 - - - - 0.00000000000001198 75.0
CSH2_k127_2622941_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000002372 81.0
CSH2_k127_2622941_7 methyltransferase - - - 0.0003244 48.0
CSH2_k127_265001_0 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008544 279.0
CSH2_k127_265001_1 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001335 168.0
CSH2_k127_265001_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000253 148.0
CSH2_k127_265001_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000246 101.0
CSH2_k127_265001_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000009167 95.0
CSH2_k127_265001_5 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000005432 90.0
CSH2_k127_2656919_0 PFAM elongation factor Tu domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000024 229.0
CSH2_k127_2656919_1 SMART Elongator protein 3 MiaB NifB K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000001105 51.0
CSH2_k127_2675218_0 DNA polymerase type-B family K02319 - 2.7.7.7 1.646e-257 813.0
CSH2_k127_2687591_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 499.0
CSH2_k127_2689679_0 Bacterial Ig-like domain 2 - - - 0.00000000009683 75.0
CSH2_k127_2689679_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0002391 54.0
CSH2_k127_2738447_0 polysaccharide catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000352 208.0
CSH2_k127_2738447_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.0000000000000000000000000000000000000000000000005247 191.0
CSH2_k127_2749177_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000001668 219.0
CSH2_k127_2749177_1 Archaeal Type IV pilin, N-terminal - - - 0.0000000000000000000000000000000000000000002804 179.0
CSH2_k127_2749177_2 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000007813 63.0
CSH2_k127_2753027_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 464.0
CSH2_k127_2753027_1 - - - - 0.000000000000000002027 92.0
CSH2_k127_2753027_2 - - - - 0.000000000000104 76.0
CSH2_k127_2753027_3 - - - - 0.0000368 49.0
CSH2_k127_2753027_4 PhoU domain - - - 0.000729 44.0
CSH2_k127_2758514_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 303.0
CSH2_k127_2758514_1 nucleotidyltransferase activity - - - 0.0000000000000000000001208 103.0
CSH2_k127_2758514_2 PRC-barrel domain protein - - - 0.0007497 46.0
CSH2_k127_2769872_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.484e-273 854.0
CSH2_k127_2769872_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 561.0
CSH2_k127_2769872_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 445.0
CSH2_k127_2769872_3 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 380.0
CSH2_k127_2769872_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000002156 126.0
CSH2_k127_2769935_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 335.0
CSH2_k127_2769935_1 Double zinc ribbon - - - 0.00000000000000000000000000001463 132.0
CSH2_k127_2769935_2 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000001137 83.0
CSH2_k127_2769935_3 Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes K09613 GO:0000003,GO:0000338,GO:0000749,GO:0000754,GO:0000909,GO:0003006,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008180,GO:0008233,GO:0008234,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0010893,GO:0016787,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019538,GO:0019783,GO:0019784,GO:0019953,GO:0022414,GO:0023051,GO:0023058,GO:0030447,GO:0030448,GO:0030582,GO:0030584,GO:0031136,GO:0031137,GO:0031139,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032443,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0036211,GO:0040007,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045116,GO:0045834,GO:0045940,GO:0046889,GO:0046890,GO:0046999,GO:0048518,GO:0048522,GO:0048583,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050810,GO:0050896,GO:0051704,GO:0051716,GO:0061458,GO:0062012,GO:0062013,GO:0065007,GO:0070011,GO:0070452,GO:0070646,GO:0070647,GO:0070791,GO:0070887,GO:0071310,GO:0071444,GO:0071704,GO:0075259,GO:0080090,GO:0106118,GO:0106120,GO:0140096,GO:1901564,GO:1902930,GO:1902932,GO:2000241,GO:2000243 - 0.000000001176 68.0
CSH2_k127_2781919_0 rhs family - - - 0.0000000000000000000000000000000000141 158.0
CSH2_k127_281385_0 ATP-grasp domain K01955 - 6.3.5.5 0.00000000000000000000000000000000004273 145.0
CSH2_k127_281385_1 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000001031 124.0
CSH2_k127_281385_2 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000004166 98.0
CSH2_k127_281385_3 Glycosyltransferase Family 4 K13668 - 2.4.1.346 0.00000001385 66.0
CSH2_k127_2824826_0 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 308.0
CSH2_k127_2824826_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000006951 242.0
CSH2_k127_2824826_2 - K21029 - 2.7.7.80 0.00000003801 58.0
CSH2_k127_2830830_0 amine dehydrogenase activity - - - 0.000000000000000000000000000009011 137.0
CSH2_k127_2830830_1 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000191 86.0
CSH2_k127_2830830_2 membrane-bound metal-dependent K07038 - - 0.0000002726 62.0
CSH2_k127_2842234_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 421.0
CSH2_k127_2842234_1 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 330.0
CSH2_k127_284731_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 322.0
CSH2_k127_284731_1 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000000000007466 102.0
CSH2_k127_2847918_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 447.0
CSH2_k127_2847918_1 Involved in the catabolism of quinolinic acid (QA) K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.000000000000000000000000000000000000000000004552 169.0
CSH2_k127_2855010_0 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000009512 152.0
CSH2_k127_2855010_1 von Willebrand factor, type A K07114 - - 0.00000000003364 69.0
CSH2_k127_286306_0 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000912 64.0
CSH2_k127_2863250_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 2.898e-202 644.0
CSH2_k127_2863250_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000001226 209.0
CSH2_k127_2882629_0 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000009552 188.0
CSH2_k127_2897623_0 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 293.0
CSH2_k127_2897623_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000001768 193.0
CSH2_k127_2897623_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000005705 161.0
CSH2_k127_2897623_3 toxin-antitoxin pair type II binding - - - 0.000000000000000202 83.0
CSH2_k127_2901322_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000004965 238.0
CSH2_k127_2901322_1 Bacterial Ig-like domain - - - 0.00000001102 66.0
CSH2_k127_2906542_0 CotH kinase protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 467.0
CSH2_k127_2909839_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 360.0
CSH2_k127_2932984_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 319.0
CSH2_k127_2932984_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000006197 134.0
CSH2_k127_2933907_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 364.0
CSH2_k127_2933907_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.0000000000000000000000000000001044 127.0
CSH2_k127_2941564_0 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 304.0
CSH2_k127_2941564_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000007638 210.0
CSH2_k127_2941564_2 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000001786 177.0
CSH2_k127_2941564_3 S-layer protein - - - 0.00002529 59.0
CSH2_k127_2972265_0 von Willebrand factor, type A K07114 - - 0.000002444 59.0
CSH2_k127_2977307_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000007404 188.0
CSH2_k127_3000851_0 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 357.0
CSH2_k127_3000851_1 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003449 274.0
CSH2_k127_3000851_2 ABC-2 type transporter K01992 - - 0.000000000000000000000000000001705 126.0
CSH2_k127_3000851_3 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000002853 66.0
CSH2_k127_3011541_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000002339 235.0
CSH2_k127_3011541_1 - - - - 0.000001952 55.0
CSH2_k127_3011541_2 adenyl ribonucleotide binding - - - 0.0006697 45.0
CSH2_k127_3012255_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 9.081e-206 653.0
CSH2_k127_3014190_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.29e-254 811.0
CSH2_k127_3014190_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.0007619 44.0
CSH2_k127_3021750_0 Patch-forming domain C2 of tRNA-guanine transglycosylase K07557 GO:0002927,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.6.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000007515 265.0
CSH2_k127_3021750_1 GTPase of K06942 - - 0.0000000000000000000000000005418 124.0
CSH2_k127_3028818_0 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000001653 237.0
CSH2_k127_3028818_1 - - - - 0.00000000000006656 78.0
CSH2_k127_3028818_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000001542 72.0
CSH2_k127_3028818_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000001756 53.0
CSH2_k127_304715_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000001564 79.0
CSH2_k127_304715_1 EamA-like transporter family - - - 0.00000000103 61.0
CSH2_k127_3063348_0 MviN-like protein - - - 0.000000000000000000000000000000000000000000000001834 199.0
CSH2_k127_3063348_1 - - - - 0.00000000000000004476 92.0
CSH2_k127_3063348_2 Ring finger - - - 0.0008138 45.0
CSH2_k127_3082812_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 515.0
CSH2_k127_3082812_1 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 393.0
CSH2_k127_3082812_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000004129 211.0
CSH2_k127_3082812_3 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000448 195.0
CSH2_k127_3082812_4 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000001441 179.0
CSH2_k127_3082812_5 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000000000006114 157.0
CSH2_k127_3082812_6 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.00000000000000003571 89.0
CSH2_k127_3082812_7 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000004359 64.0
CSH2_k127_3082812_8 FtsX-like permease family K02004 - - 0.00006766 51.0
CSH2_k127_3082812_9 membrane - - - 0.0002364 52.0
CSH2_k127_3088946_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 310.0
CSH2_k127_3088946_1 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 302.0
CSH2_k127_3088946_2 Protein of unknown function TPD sequence-motif - - - 0.00000000000000000000000000000000000000000000000000000000002742 223.0
CSH2_k127_3088946_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000004288 190.0
CSH2_k127_310502_0 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000002867 233.0
CSH2_k127_310502_1 TIGRFAM segregation and condensation protein B K06024 - - 0.0000000000000000000000000000001164 132.0
CSH2_k127_310502_2 chromosome segregation and condensation protein ScpA K05896 - - 0.00000000005586 67.0
CSH2_k127_3106090_0 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000007678 156.0
CSH2_k127_3106090_1 methyltransferase activity - - - 0.00000000000000000000000000000000000001508 155.0
CSH2_k127_3167785_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000002023 164.0
CSH2_k127_3167785_1 Pfam:KaiC - - - 0.000000000000000000000000000002522 126.0
CSH2_k127_3167785_2 Winged helix-turn-helix DNA-binding - - - 0.00000277 58.0
CSH2_k127_3182025_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.839e-273 852.0
CSH2_k127_3182025_1 OmpA family K02557,K03286 - - 0.000000000001053 79.0
CSH2_k127_3182025_2 cellulase activity K01179 - 3.2.1.4 0.0000000722 64.0
CSH2_k127_319458_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 385.0
CSH2_k127_319458_1 PFAM Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007565 274.0
CSH2_k127_319458_2 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000002342 237.0
CSH2_k127_319458_3 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000001093 217.0
CSH2_k127_319458_4 Desulfoferrodoxin ferrous iron-binding K05919 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016721,GO:0019430,GO:0022900,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.2 0.0000000005207 62.0
CSH2_k127_3198042_0 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 451.0
CSH2_k127_3198042_1 integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 314.0
CSH2_k127_3198042_2 PKD domain - - - 0.00000000000002222 88.0
CSH2_k127_3198042_3 protein kinase activity - - - 0.00008494 56.0
CSH2_k127_3228061_0 PFAM Peptidase C1A, papain - - - 0.0000000000000000000000005581 122.0
CSH2_k127_3263019_0 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 402.0
CSH2_k127_3263019_1 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000007933 174.0
CSH2_k127_3263019_2 GDP-mannose 4,6 dehydratase K01784 GO:0002164,GO:0002376,GO:0002520,GO:0003674,GO:0003824,GO:0003974,GO:0003978,GO:0005975,GO:0005996,GO:0006012,GO:0007275,GO:0008150,GO:0008152,GO:0009791,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0030097,GO:0032501,GO:0032502,GO:0035166,GO:0035167,GO:0044238,GO:0044281,GO:0048513,GO:0048534,GO:0048542,GO:0048569,GO:0048731,GO:0048732,GO:0048856,GO:0071704 5.1.3.2 0.00005104 51.0
CSH2_k127_3265327_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 399.0
CSH2_k127_3265327_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01464,K01465,K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.2,3.5.2.3,3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 304.0
CSH2_k127_3265327_2 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000836 252.0
CSH2_k127_3265327_3 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000001627 237.0
CSH2_k127_3265327_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000005334 222.0
CSH2_k127_3265327_5 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000001054 218.0
CSH2_k127_3265327_6 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000008539 191.0
CSH2_k127_3265327_7 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000005277 119.0
CSH2_k127_3265327_8 Rubrerythrin K19824 - - 0.0000000001058 63.0
CSH2_k127_3265327_9 Protein of unknown function (DUF1634) - - - 0.00005265 51.0
CSH2_k127_3270879_0 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 456.0
CSH2_k127_3270879_1 DeoC/LacD family aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 418.0
CSH2_k127_3270879_2 protein conserved in archaea - - - 0.000000000000000000006171 98.0
CSH2_k127_3296014_0 - - - - 0.00000000000000002213 96.0
CSH2_k127_3296014_1 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.000000000000006149 79.0
CSH2_k127_3296014_2 Peroxiredoxin Q K03564 - 1.11.1.15 0.0002443 51.0
CSH2_k127_3302725_0 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000006674 166.0
CSH2_k127_3302725_1 Phosphorylase superfamily K00757 GO:0003674,GO:0003824,GO:0004850,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006218,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016043,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0022607,GO:0030955,GO:0031420,GO:0033554,GO:0034214,GO:0034641,GO:0034655,GO:0034656,GO:0042454,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046108,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0050896,GO:0051259,GO:0051716,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.3 0.0000003413 53.0
CSH2_k127_3319445_0 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000000000000005486 194.0
CSH2_k127_3319445_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000001048 130.0
CSH2_k127_3319445_2 Sigma-54 interaction domain K03405 - 6.6.1.1 0.000000000008559 74.0
CSH2_k127_3347889_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 421.0
CSH2_k127_3347889_1 biogenesis protein CcmF K02198 - - 0.000000000000000000000000000000000000000000000000004913 205.0
CSH2_k127_3347889_2 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000001565 113.0
CSH2_k127_3347889_3 Glucose sorbosone - - - 0.0001557 55.0
CSH2_k127_3357667_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 3.895e-241 758.0
CSH2_k127_3357667_1 GTPase of unknown function C-terminal K06942 - - 0.000000000000000000000000001916 112.0
CSH2_k127_3357667_2 TGS domain protein K06942 - - 0.000001602 51.0
CSH2_k127_3357667_3 Phosphodiester glycosidase - - - 0.00001291 58.0
CSH2_k127_336030_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 436.0
CSH2_k127_336030_1 Psort location Cytoplasmic, score 8.96 K01163 - - 0.00000000000000000000000000000000000000000000000007723 190.0
CSH2_k127_336030_2 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000005823 122.0
CSH2_k127_336030_3 - - - - 0.00000000000000000000000001677 110.0
CSH2_k127_3360887_0 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 408.0
CSH2_k127_3360887_1 protein conserved in archaea K09746 - - 0.0000000000000000000002306 104.0
CSH2_k127_3360887_2 - - - - 0.00008963 47.0
CSH2_k127_3368842_0 - - - - 0.0000000000000000000000000000000000003326 151.0
CSH2_k127_3368842_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000005117 147.0
CSH2_k127_3368842_2 lipoprotein localization to outer membrane K02004 - - 0.0000000004038 68.0
CSH2_k127_338366_0 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.00000000000000000000000000000000000000000000000000000000000000000003653 254.0
CSH2_k127_3391956_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 4.834e-205 650.0
CSH2_k127_3391956_1 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 458.0
CSH2_k127_3391956_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003406 267.0
CSH2_k127_3391956_3 ribosomal protein K02907 - - 0.0000000000000000000000000000000000362 141.0
CSH2_k127_3391956_4 ribosomal protein L15 K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000001824 124.0
CSH2_k127_3391956_5 Protein of unknown function DUF47 K07220 - - 0.00000000001446 66.0
CSH2_k127_3451826_0 Cytochrome c biogenesis protein transmembrane region K06196 - - 0.00003698 55.0
CSH2_k127_3457551_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 548.0
CSH2_k127_3457551_1 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 497.0
CSH2_k127_3457551_2 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 473.0
CSH2_k127_3457551_3 polysaccharide catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002908 255.0
CSH2_k127_3457551_4 Universal stress protein - - - 0.0000001022 62.0
CSH2_k127_3457551_5 - - - - 0.0002712 53.0
CSH2_k127_3466689_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 506.0
CSH2_k127_3466689_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001487 286.0
CSH2_k127_3482691_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.572e-262 829.0
CSH2_k127_3482691_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 429.0
CSH2_k127_3482691_2 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 380.0
CSH2_k127_3482691_3 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 319.0
CSH2_k127_3482691_4 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000485 287.0
CSH2_k127_3482691_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000002152 219.0
CSH2_k127_3482691_6 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000003981 196.0
CSH2_k127_3482691_7 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000919 92.0
CSH2_k127_3482691_8 YHS domain - - - 0.00000000000000001782 84.0
CSH2_k127_3482691_9 Beta-lactamase superfamily domain - - - 0.00001271 48.0
CSH2_k127_3513776_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 334.0
CSH2_k127_3513776_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000008012 269.0
CSH2_k127_352634_0 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000006485 160.0
CSH2_k127_3549618_0 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007385 249.0
CSH2_k127_3549618_1 PFAM PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000007555 209.0
CSH2_k127_3549618_2 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000003119 155.0
CSH2_k127_3549618_3 Subtilase family K17734 - - 0.000000000000000000000000004664 125.0
CSH2_k127_3552669_0 Right handed beta helix region - - - 0.0000000000006943 78.0
CSH2_k127_3552669_1 PFAM Metallophosphoesterase - - - 0.00000000008069 73.0
CSH2_k127_3570864_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 346.0
CSH2_k127_3570864_1 - - - - 0.0000000000000000000000000000000008075 141.0
CSH2_k127_3570864_2 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 0.0000402 49.0
CSH2_k127_3570864_3 - - - - 0.0001012 54.0
CSH2_k127_3580096_0 Cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 372.0
CSH2_k127_3580096_1 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009939 271.0
CSH2_k127_3580096_2 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000002179 207.0
CSH2_k127_3580096_3 ABC-2 type transporter - - - 0.00000000000000001626 93.0
CSH2_k127_3590189_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 600.0
CSH2_k127_3590189_1 chromosome segregation and condensation protein ScpA K05896 - - 0.00000000000000000000000001175 118.0
CSH2_k127_3607393_0 Aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 3.56e-206 651.0
CSH2_k127_3607393_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 292.0
CSH2_k127_3614233_0 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 306.0
CSH2_k127_3614233_1 PFAM Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006971 280.0
CSH2_k127_3614233_2 Photosynthesis system II assembly factor YCF48 - - - 0.00014 47.0
CSH2_k127_3659970_0 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 308.0
CSH2_k127_3659970_1 ABC transporter K02031 - - 0.00000000000000000001837 96.0
CSH2_k127_3692225_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 382.0
CSH2_k127_3692225_1 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000002443 134.0
CSH2_k127_3692225_2 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.000000000000000001291 89.0
CSH2_k127_3698357_0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000008871 237.0
CSH2_k127_3698357_1 Phosphorylase superfamily K00757 - 2.4.2.3 0.000000000000000000000000000000000000000001191 164.0
CSH2_k127_3718836_0 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000532 239.0
CSH2_k127_3718836_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0004391 44.0
CSH2_k127_3757481_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 531.0
CSH2_k127_3757481_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 320.0
CSH2_k127_3757481_2 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000004969 233.0
CSH2_k127_3757481_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001033 183.0
CSH2_k127_3757481_4 Protein of unknown function (DUF835) - - - 0.000001127 59.0
CSH2_k127_3801952_0 Domain of unknown function (DUF4438) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 334.0
CSH2_k127_3801952_1 MCM OB domain K10726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006021 260.0
CSH2_k127_3801952_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000004391 186.0
CSH2_k127_3818303_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000001185 218.0
CSH2_k127_3818303_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000004141 217.0
CSH2_k127_3818303_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000003764 167.0
CSH2_k127_3818303_3 glutamine amidotransferase - - - 0.00000000005801 67.0
CSH2_k127_3818630_0 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008481 253.0
CSH2_k127_3818630_1 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.0000000000000000000000000000000000000000000000000003611 191.0
CSH2_k127_3818630_2 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000459 149.0
CSH2_k127_3852319_0 Heat shock 70 kDa protein K04043 - - 9.099e-243 756.0
CSH2_k127_3866759_0 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000104 170.0
CSH2_k127_388993_0 PFAM carboxyl transferase - - - 7.012e-221 692.0
CSH2_k127_388993_1 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000008904 72.0
CSH2_k127_3891153_0 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001471 248.0
CSH2_k127_3891153_1 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000001497 216.0
CSH2_k127_3891153_2 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000001646 181.0
CSH2_k127_393117_0 Transcription factor zinc-finger - - - 0.0000000002271 70.0
CSH2_k127_393117_1 - - - - 0.0000008588 53.0
CSH2_k127_3932607_0 KH domain K07041 - - 2.06e-268 841.0
CSH2_k127_3933673_0 PFAM Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 323.0
CSH2_k127_3933673_1 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000007247 260.0
CSH2_k127_3933673_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000002444 222.0
CSH2_k127_3933673_3 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000008953 211.0
CSH2_k127_3933673_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000001301 188.0
CSH2_k127_3944759_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 364.0
CSH2_k127_3944759_1 TIGRFAM Riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002577 251.0
CSH2_k127_3944759_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000002324 250.0
CSH2_k127_3944759_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000003255 232.0
CSH2_k127_3944759_4 transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000007599 198.0
CSH2_k127_3944759_5 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000000000002397 175.0
CSH2_k127_3944759_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000003704 171.0
CSH2_k127_3944759_7 Transcriptional regulator, TrmB - - - 0.000000009148 62.0
CSH2_k127_395098_0 Pfam:KaiC - - - 0.000000000000291 78.0
CSH2_k127_395098_1 - - - - 0.00000000008027 65.0
CSH2_k127_3962059_0 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 1.115e-213 685.0
CSH2_k127_3962059_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 409.0
CSH2_k127_3962059_2 GyrI-like small molecule binding domain - - - 0.00000000000000000002752 92.0
CSH2_k127_3998918_0 4Fe-4S binding domain - - - 0.0000000000000000000308 104.0
CSH2_k127_4002965_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 8.267e-200 630.0
CSH2_k127_4002965_1 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000004125 168.0
CSH2_k127_4002965_2 von Willebrand factor, type A K07114 - - 0.0000002627 59.0
CSH2_k127_4002965_3 von Willebrand factor, type A K07114 - - 0.000009802 58.0
CSH2_k127_403378_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 427.0
CSH2_k127_403378_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000005992 243.0
CSH2_k127_403378_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000003379 204.0
CSH2_k127_403378_3 adenyl ribonucleotide binding - - - 0.00000000000000000000000000000000000000004658 157.0
CSH2_k127_403378_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.0000000000000000000000000003104 116.0
CSH2_k127_4057785_0 Belongs to the complex I 49 kDa subunit family K00333,K14090 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 393.0
CSH2_k127_4057785_1 Belongs to the complex I 20 kDa subunit family K14088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001916 243.0
CSH2_k127_4057785_2 4Fe-4S dicluster domain K14091 - - 0.000000000000000000000000002273 115.0
CSH2_k127_4057785_3 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K14089 - - 0.0000000000000000004063 91.0
CSH2_k127_4103814_0 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000461 106.0
CSH2_k127_4103814_1 methanogenesis marker protein 11 - - - 0.000000000000000000255 90.0
CSH2_k127_4133452_0 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000000001553 109.0
CSH2_k127_4148014_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009898 362.0
CSH2_k127_4148014_1 FAD binding domain K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 0.000000000000000000000004936 102.0
CSH2_k127_4151555_0 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 487.0
CSH2_k127_4151555_1 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 388.0
CSH2_k127_4151555_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000002759 213.0
CSH2_k127_4153565_0 PFAM TPR repeat-containing protein - - - 0.0000002596 64.0
CSH2_k127_4178124_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 616.0
CSH2_k127_4178124_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002065 277.0
CSH2_k127_4178124_2 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000002756 85.0
CSH2_k127_4178124_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000003024 72.0
CSH2_k127_4178124_4 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000002543 63.0
CSH2_k127_4178124_5 Pfam:DUF650 - - - 0.0000005539 52.0
CSH2_k127_4188383_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
CSH2_k127_4188383_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 322.0
CSH2_k127_4188383_2 Isochorismatase family - - - 0.000000000000000000006924 93.0
CSH2_k127_421292_0 4Fe-4S binding domain - - - 0.000000000000000006412 84.0
CSH2_k127_421292_1 amine dehydrogenase activity - - - 0.0004487 53.0
CSH2_k127_4218840_0 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000003862 74.0
CSH2_k127_4218840_1 PFAM NHL repeat containing protein - - - 0.00000006049 66.0
CSH2_k127_4218840_2 metallopeptidase activity - - - 0.0007533 52.0
CSH2_k127_42347_0 PFAM ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 344.0
CSH2_k127_42347_1 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.00000000000000000000000000000000000000000000000000000000000005362 220.0
CSH2_k127_42347_2 Fibronectin type III domain - - - 0.000000000000000000000000000000143 140.0
CSH2_k127_4251178_0 prohibitin homologues K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003289 283.0
CSH2_k127_427434_0 von Willebrand factor, type A K07114 - - 0.00003237 53.0
CSH2_k127_4277124_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 481.0
CSH2_k127_4277124_1 - - - - 0.0000000000000000000000000000000000000000006064 162.0
CSH2_k127_428222_0 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000001269 65.0
CSH2_k127_428222_1 this gene contains a nucleotide ambiguity which may be the result of a sequencing error K20276 - - 0.00001403 58.0
CSH2_k127_4334638_0 protein conserved in archaea - - - 0.000000000000002082 83.0
CSH2_k127_4334638_1 Protein of unknown function DUF131 - - - 0.0000000000001654 76.0
CSH2_k127_4341996_0 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 576.0
CSH2_k127_4341996_1 - - - - 0.0001424 52.0
CSH2_k127_4353729_0 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004631 283.0
CSH2_k127_4353729_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000157 127.0
CSH2_k127_4353729_2 Leucyl aminopeptidase K19701 - 3.4.11.10,3.4.11.6 0.000000000000000000000002001 121.0
CSH2_k127_4353729_3 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.0000000000000424 85.0
CSH2_k127_4353729_4 O-linked N-acetylglucosamine transferase, SPINDLY family - - - 0.000000000007675 77.0
CSH2_k127_4353729_5 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00002829 53.0
CSH2_k127_4359384_0 TIGRFAM Small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 408.0
CSH2_k127_4359384_1 SMART AAA ATPase K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 385.0
CSH2_k127_4359384_2 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 328.0
CSH2_k127_4359384_3 SMART AAA ATPase K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000008865 206.0
CSH2_k127_4359384_4 - - - - 0.00000000000000000000000000000000000000000000002917 189.0
CSH2_k127_4359384_5 SMART AAA ATPase K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000001949 157.0
CSH2_k127_4359384_6 von Willebrand factor (vWF) type A domain K03404 - 6.6.1.1 0.00000000000000000000000000002644 135.0
CSH2_k127_4359384_7 Tetratricopeptide repeat - - - 0.000000000000000000000001046 122.0
CSH2_k127_4359384_8 Protein of unknown function (DUF835) - - - 0.0004389 54.0
CSH2_k127_4375579_0 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 292.0
CSH2_k127_4375579_1 Glyoxalase-like domain K05606 GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 0.000000000000000000000000000000000000000005071 158.0
CSH2_k127_4419620_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 295.0
CSH2_k127_4419620_1 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001694 266.0
CSH2_k127_4465906_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 389.0
CSH2_k127_4465906_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000003335 241.0
CSH2_k127_4465906_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000005606 90.0
CSH2_k127_4478242_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000003224 129.0
CSH2_k127_4478242_1 Arrestin (or S-antigen), C-terminal domain - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0008150,GO:0009892,GO:0010468,GO:0010605,GO:0010629,GO:0019222,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0060255,GO:0065007 - 0.0000001398 62.0
CSH2_k127_4478242_2 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0001691 49.0
CSH2_k127_4486441_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 552.0
CSH2_k127_4486441_1 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.00000000000000000000000000000000000000000000000000000000000001235 220.0
CSH2_k127_4486441_2 TIGRFAM RNA methyltransferase, TrmH family, group 1 - - - 0.000000000000000000000000000000000000000000000008452 181.0
CSH2_k127_4486441_3 Glycosyl transferase 4-like - - - 0.0000000000000001057 85.0
CSH2_k127_4489644_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000005722 220.0
CSH2_k127_4489644_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000008363 136.0
CSH2_k127_4489644_2 von Willebrand factor type A domain - GO:0003674,GO:0003824,GO:0004842,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009605,GO:0009606,GO:0009628,GO:0009629,GO:0009630,GO:0009987,GO:0016020,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0022622,GO:0032446,GO:0032501,GO:0032502,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048364,GO:0048731,GO:0048856,GO:0050896,GO:0061630,GO:0061659,GO:0070647,GO:0071704,GO:0071944,GO:0099402,GO:0140096,GO:1901564 - 0.000004461 59.0
CSH2_k127_4527075_0 TIGRFAM small GTP-binding protein domain - - - 0.00000000000000000000000002819 115.0
CSH2_k127_4527075_1 cheY-homologous receiver domain - - - 0.000000000000000000004356 104.0
CSH2_k127_4527302_0 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000154 184.0
CSH2_k127_4527302_1 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000000006075 153.0
CSH2_k127_4527302_2 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000006578 66.0
CSH2_k127_4543059_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 327.0
CSH2_k127_4543059_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000004972 168.0
CSH2_k127_4543059_2 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000000001262 147.0
CSH2_k127_4543059_3 NMD3 family K07562 - - 0.00000000000000000000000000000000004961 147.0
CSH2_k127_4543059_4 transferase activity, transferring glycosyl groups - - - 0.000000000000000002525 98.0
CSH2_k127_4543059_5 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.000000002118 62.0
CSH2_k127_4566537_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 596.0
CSH2_k127_4566537_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.0000000000000000000000000000000000000000000000000004417 194.0
CSH2_k127_4566537_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000000000000004465 97.0
CSH2_k127_4567938_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 426.0
CSH2_k127_4586708_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 340.0
CSH2_k127_4586708_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 303.0
CSH2_k127_4586708_2 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000001104 213.0
CSH2_k127_4586708_3 U4 snRNA binding K11127 - - 0.0000000000000000000000000000000000000000000001044 184.0
CSH2_k127_4586708_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000003327 112.0
CSH2_k127_4586708_5 RNA binding K07581 - - 0.00000000001609 71.0
CSH2_k127_4586708_6 COG1520 FOG WD40-like repeat - - - 0.0000001867 63.0
CSH2_k127_4586708_7 Putative zinc- or iron-chelating domain K06940 - - 0.0006761 51.0
CSH2_k127_4589346_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 540.0
CSH2_k127_4589346_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 340.0
CSH2_k127_4589346_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002832 276.0
CSH2_k127_4589346_3 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000002753 219.0
CSH2_k127_4619971_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000008401 177.0
CSH2_k127_4619971_1 exo-alpha-(2->6)-sialidase activity - - - 0.0003016 53.0
CSH2_k127_4631066_0 Inverse autotransporter, beta-domain K13735 - - 0.00004502 56.0
CSH2_k127_4657663_0 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000006749 197.0
CSH2_k127_4680897_0 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 348.0
CSH2_k127_4680897_1 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002994 221.0
CSH2_k127_4680897_2 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000004151 188.0
CSH2_k127_4680897_3 Oxidoreductase domain protein K18855 - 1.1.1.374 0.000000000000000000000000000000000003863 143.0
CSH2_k127_4680897_4 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000001784 127.0
CSH2_k127_4680897_5 Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat - - - 0.0000003827 60.0
CSH2_k127_468277_0 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 380.0
CSH2_k127_468277_1 phosphate-selective porin O and P - - - 0.000000007994 61.0
CSH2_k127_468277_2 - - - - 0.0000003758 55.0
CSH2_k127_4717666_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.964e-250 790.0
CSH2_k127_4717666_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 342.0
CSH2_k127_4717666_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000312 231.0
CSH2_k127_4724250_0 helicase superfamily c-terminal domain K03724 - - 1.69e-240 773.0
CSH2_k127_4724250_1 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.00000000000000008315 80.0
CSH2_k127_4724250_2 PAS domain K02488 - 2.7.7.65 0.0000000000001845 74.0
CSH2_k127_4757937_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 434.0
CSH2_k127_4757937_1 Ribosomal protein S8e K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000000000369 141.0
CSH2_k127_4757937_2 DnaB-like helicase C terminal domain - - - 0.000000000000000000000000000000000006104 145.0
CSH2_k127_4757937_3 COG0608 Single-stranded DNA-specific exonuclease K07463 - - 0.00000000000000000002021 93.0
CSH2_k127_4757937_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.00000000000000000007532 93.0
CSH2_k127_4757937_5 AsnC family - - - 0.00055 46.0
CSH2_k127_4828144_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 377.0
CSH2_k127_4828144_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 296.0
CSH2_k127_4828144_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000002624 129.0
CSH2_k127_4828144_3 Transcription factor zinc-finger - - - 0.0000005586 62.0
CSH2_k127_4837996_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 326.0
CSH2_k127_4837996_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000005409 229.0
CSH2_k127_4837996_2 - - - - 0.0000000000000000000000005456 112.0
CSH2_k127_4837996_3 - - - - 0.000000000000003941 78.0
CSH2_k127_4837996_4 - - - - 0.000006058 51.0
CSH2_k127_4889356_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 476.0
CSH2_k127_4889356_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 318.0
CSH2_k127_4889356_2 TatD related DNase K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000298 221.0
CSH2_k127_4889356_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000001204 156.0
CSH2_k127_4896073_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 361.0
CSH2_k127_4908074_0 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 331.0
CSH2_k127_4908074_1 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000003042 224.0
CSH2_k127_4912480_0 - - - - 0.000000000000000000000000000000002652 139.0
CSH2_k127_4912480_1 Putative zinc- or iron-chelating domain - - - 0.00000000000000000002663 98.0
CSH2_k127_4912480_2 4Fe-4S binding domain - - - 0.00000003237 58.0
CSH2_k127_4913640_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 438.0
CSH2_k127_4913640_1 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000661 164.0
CSH2_k127_4913640_2 EamA-like transporter family - - - 0.000000000000000000000000002841 123.0
CSH2_k127_4913640_3 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.0000000000000000000003241 101.0
CSH2_k127_4913640_4 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.000000000000002305 81.0
CSH2_k127_4913640_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000006861 81.0
CSH2_k127_4917273_0 membrane - - - 0.000000000000000000000000003098 120.0
CSH2_k127_4919990_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000006852 70.0
CSH2_k127_4923510_0 GHMP kinases C terminal K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000002986 206.0
CSH2_k127_4923510_1 ZIP Zinc transporter K07238 - - 0.00000006764 62.0
CSH2_k127_4924631_0 von Willebrand factor type A domain K07114 - - 0.000004509 59.0
CSH2_k127_493650_0 TIGRFAM TIGR00268 family protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000006766 235.0
CSH2_k127_493650_1 AIR carboxylase K06898 - - 0.0000000000000000000000000000000004061 138.0
CSH2_k127_493650_2 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000001779 117.0
CSH2_k127_4942879_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 498.0
CSH2_k127_4942879_1 L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 375.0
CSH2_k127_4942879_2 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.00000000000000000000000000000001508 132.0
CSH2_k127_4968059_0 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000578 250.0
CSH2_k127_4968059_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000001078 164.0
CSH2_k127_4970807_0 amine dehydrogenase activity - - - 0.0000000000006866 83.0
CSH2_k127_4970807_1 amine dehydrogenase activity - - - 0.000000000008818 78.0
CSH2_k127_4970807_2 OmpA family - - - 0.000000006119 70.0
CSH2_k127_4970807_3 ABC-type uncharacterized transport system - - - 0.0000215 57.0
CSH2_k127_4986073_0 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 336.0
CSH2_k127_4986073_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003137 282.0
CSH2_k127_4988714_0 pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 426.0
CSH2_k127_4988714_1 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000003336 123.0
CSH2_k127_4988714_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000004264 67.0
CSH2_k127_4993039_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 302.0
CSH2_k127_4993039_1 PAC2 family K07159 - - 0.000000000000000000000001032 105.0
CSH2_k127_4993039_2 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000003659 68.0
CSH2_k127_4993039_3 Ribosomal protein S27E K02978 - - 0.00000003474 55.0
CSH2_k127_5019758_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000002119 211.0
CSH2_k127_5019758_1 metallopeptidase activity - - - 0.0000001529 59.0
CSH2_k127_5023225_0 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000001946 172.0
CSH2_k127_5023225_1 BioY family K03523 - - 0.000000000000000000000000000000007448 135.0
CSH2_k127_5037485_0 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 387.0
CSH2_k127_5037485_1 PFAM ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 336.0
CSH2_k127_5037485_10 Binds to the 23S rRNA K02896 - - 0.0000000000000000000004941 98.0
CSH2_k127_5037485_11 Zinc finger domain - - - 0.0003888 47.0
CSH2_k127_5037485_2 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006897 278.0
CSH2_k127_5037485_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000002196 240.0
CSH2_k127_5037485_4 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.00000000000000000000000000000000000000000000000002531 181.0
CSH2_k127_5037485_5 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000001829 187.0
CSH2_k127_5037485_6 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000003727 175.0
CSH2_k127_5037485_7 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000000000000000000001313 149.0
CSH2_k127_5037485_8 Regulatory protein Crp K07730 - - 0.00000000000000000000000000124 123.0
CSH2_k127_5037485_9 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.0000000000000000000000002284 106.0
CSH2_k127_5039435_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 421.0
CSH2_k127_5039435_1 Glycinamide ribonucleotide synthetase K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000003827 172.0
CSH2_k127_5039435_2 von Willebrand factor (vWF) type A domain - - - 0.0001088 51.0
CSH2_k127_5074921_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 421.0
CSH2_k127_5074921_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000001738 67.0
CSH2_k127_5078178_0 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000001454 131.0
CSH2_k127_5089344_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 3.12e-230 720.0
CSH2_k127_5089344_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 459.0
CSH2_k127_5089344_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000001281 236.0
CSH2_k127_5108754_0 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000005992 243.0
CSH2_k127_5108754_1 Glycosyl hydrolase family 63 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001335 241.0
CSH2_k127_5108754_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000003901 234.0
CSH2_k127_5108754_3 - - - - 0.000002709 52.0
CSH2_k127_5125642_0 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000007377 176.0
CSH2_k127_5125642_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0007853 51.0
CSH2_k127_5170296_0 DNA-binding transcription factor activity K07728 - - 0.00000000000000000000000000000000000000000000001531 178.0
CSH2_k127_5170296_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000001669 149.0
CSH2_k127_5170296_2 - - - - 0.000000000000000000000000000001983 132.0
CSH2_k127_5172862_0 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 342.0
CSH2_k127_5172862_1 cyclohydrolase K01746 - 4.3.1.4 0.000000000000000000000000000000000000000005434 163.0
CSH2_k127_5172862_2 cytidine and deoxycytidylate deaminase K01489 - 3.5.4.5 0.000000000000001083 82.0
CSH2_k127_5174239_0 CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 553.0
CSH2_k127_5178829_0 Kelch motif - - - 0.000000000000000000000000000000000000000004284 175.0
CSH2_k127_5178829_1 Invasin, domain 3 K13735 - - 0.0000002142 63.0
CSH2_k127_5193637_0 Aminotransferase class-V - - - 0.00000000000000000000000000002166 124.0
CSH2_k127_5193637_1 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000006091 119.0
CSH2_k127_5193637_2 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.0000004783 61.0
CSH2_k127_5193637_3 - - - - 0.000003167 59.0
CSH2_k127_5195770_0 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000009882 229.0
CSH2_k127_5195770_1 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000009394 210.0
CSH2_k127_5195770_2 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.00000000000000000000006774 101.0
CSH2_k127_5195770_3 transcriptional regulators - - - 0.0005653 51.0
CSH2_k127_5216884_0 TIGRFAM geranylgeranyl reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003003 256.0
CSH2_k127_5216884_1 zinc ion binding - - - 0.000000000000000000000000000000000000001233 154.0
CSH2_k127_5216884_2 COG1361 S-layer domain - - - 0.000000000000006917 81.0
CSH2_k127_5216884_3 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000114 57.0
CSH2_k127_5224714_0 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000001298 237.0
CSH2_k127_5224714_1 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000000002607 162.0
CSH2_k127_5224714_2 Rhomboid family - - - 0.000000000000000000001059 106.0
CSH2_k127_5224714_3 Trm112p-like protein - - - 0.000000000000000007645 93.0
CSH2_k127_5224714_4 but it may be involved in stabilization of the trimeric complex - - - 0.000000002803 59.0
CSH2_k127_5224714_5 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.00000001679 66.0
CSH2_k127_5224714_6 Belongs to the group II decarboxylase family. MfnA subfamily K18933 - 4.1.1.11,4.1.1.25 0.0002065 44.0
CSH2_k127_5229511_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000002527 224.0
CSH2_k127_5229511_1 PFAM Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000005312 214.0
CSH2_k127_5229511_2 Prokaryotic homologs of the JAB domain - - - 0.000000000000000000000000000004927 125.0
CSH2_k127_5235551_0 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000000000008499 225.0
CSH2_k127_5235551_1 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000001347 209.0
CSH2_k127_5235551_2 Signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000001059 143.0
CSH2_k127_5235551_3 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000004305 128.0
CSH2_k127_5235551_4 Fcf1 K07158 - - 0.00000000000001111 79.0
CSH2_k127_5237717_0 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 319.0
CSH2_k127_5237717_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 288.0
CSH2_k127_5237717_2 - - - - 0.00000000000000000000000000000000000000000000000000000008688 213.0
CSH2_k127_5237717_3 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000002362 140.0
CSH2_k127_5237717_4 - - - - 0.00000000001306 68.0
CSH2_k127_5240334_0 NADH dehydrogenase K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 552.0
CSH2_k127_5240334_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 305.0
CSH2_k127_5240334_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000002461 166.0
CSH2_k127_527158_0 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000226 247.0
CSH2_k127_527158_1 Archaeal holliday junction resolvase (hjc) - - - 0.0000000000000000000000000000000000000000008238 163.0
CSH2_k127_527158_2 MgtC family - - - 0.00000000000000000000000000008237 127.0
CSH2_k127_527158_3 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000009764 96.0
CSH2_k127_527244_0 PFAM 2-hydroxyglutaryl-CoA dehydratase D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005987 290.0
CSH2_k127_527244_1 Cytochrome C biogenesis protein transmembrane region - - - 0.0001966 52.0
CSH2_k127_5308983_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 497.0
CSH2_k127_5308983_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008743,GO:0009066,GO:0009987,GO:0016043,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0070401,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 377.0
CSH2_k127_5308983_2 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 345.0
CSH2_k127_5308983_3 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
CSH2_k127_5308983_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000001741 221.0
CSH2_k127_5308983_5 pyridoxal phosphate-dependent acyltransferase K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000006157 173.0
CSH2_k127_5309870_0 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0005709 53.0
CSH2_k127_5334301_0 Type II/IV secretion system protein K07332 - - 1.183e-210 669.0
CSH2_k127_5334301_1 Type II secretion system K07333 - - 0.0000000000000000000000000000000000005106 149.0
CSH2_k127_5334301_2 metallopeptidase activity - - - 0.000003135 57.0
CSH2_k127_534289_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 343.0
CSH2_k127_534289_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 323.0
CSH2_k127_534289_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000001077 242.0
CSH2_k127_5359952_0 PrgI family protein - - - 0.0005305 48.0
CSH2_k127_5383831_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000001435 110.0
CSH2_k127_5383831_1 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000001783 71.0
CSH2_k127_5411692_0 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000002632 202.0
CSH2_k127_5411692_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000002813 127.0
CSH2_k127_5420647_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 484.0
CSH2_k127_5420647_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.0000000000000000000000000000000000000000009824 170.0
CSH2_k127_5436210_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 365.0
CSH2_k127_5441780_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 338.0
CSH2_k127_5441780_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0002115 47.0
CSH2_k127_5470997_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 398.0
CSH2_k127_5470997_1 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 329.0
CSH2_k127_5470997_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000002892 228.0
CSH2_k127_5470997_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.00000000000000000000000000000000000000000000004063 176.0
CSH2_k127_5470997_4 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000001755 173.0
CSH2_k127_5470997_5 nucleotide metabolic process - - - 0.00000000000000000000000000000000000005945 152.0
CSH2_k127_5470997_6 KaiC - - - 0.00000000000000000000007208 107.0
CSH2_k127_5470997_7 Major facilitator superfamily K08153 - - 0.000001185 57.0
CSH2_k127_5471573_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 5.189e-198 630.0
CSH2_k127_5471573_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000134 60.0
CSH2_k127_5473758_0 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009212 281.0
CSH2_k127_5473758_2 NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000002655 60.0
CSH2_k127_5476897_0 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 462.0
CSH2_k127_5476897_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008314 286.0
CSH2_k127_5476897_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000000000000000000000000000000000008189 202.0
CSH2_k127_5476897_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000001672 139.0
CSH2_k127_5476897_4 Oxidoreductase NAD-binding domain K00528,K02823,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000002508 106.0
CSH2_k127_5476897_5 COG0517 FOG CBS domain - - - 0.0000000000000000007378 94.0
CSH2_k127_5481789_0 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 293.0
CSH2_k127_5481789_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000006032 211.0
CSH2_k127_5481789_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001179 203.0
CSH2_k127_5481789_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000003937 172.0
CSH2_k127_5481789_4 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001442 169.0
CSH2_k127_5481789_5 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000008399 164.0
CSH2_k127_5481789_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000007052 160.0
CSH2_k127_5481789_7 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000002087 151.0
CSH2_k127_5481789_8 ribosomal protein S14 K02954 - - 0.0000000000000001236 86.0
CSH2_k127_5485509_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 522.0
CSH2_k127_5485509_1 Domain of unknown function (DUF362) K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 372.0
CSH2_k127_5485509_2 Mycolic acid cyclopropane synthetase - - - 0.00000000000001253 83.0
CSH2_k127_5492181_0 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000003936 132.0
CSH2_k127_5492181_1 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.000000000000000000000000000000001836 135.0
CSH2_k127_5492181_2 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000008926 104.0
CSH2_k127_5492181_3 - - - - 0.0005322 49.0
CSH2_k127_5561952_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000004969 189.0
CSH2_k127_5568884_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 1.062e-280 879.0
CSH2_k127_5568884_1 PRC-barrel domain - - - 0.0000000000000000000000001253 108.0
CSH2_k127_5583408_0 Fad dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 337.0
CSH2_k127_5583408_1 PFAM Peptidase - - - 0.00000000000000000000000000000000001238 145.0
CSH2_k127_5583408_2 Domain of unknown function (DUF2088) - - - 0.0000000000000000000003889 99.0
CSH2_k127_5607407_0 Pfam:Methyltransf_26 K02493 - 2.1.1.297 0.0000000000000000000000000000000004892 138.0
CSH2_k127_5607407_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000002184 104.0
CSH2_k127_5607407_2 Kelch - GO:0000003,GO:0000133,GO:0000278,GO:0000281,GO:0000746,GO:0000747,GO:0000755,GO:0000910,GO:0000935,GO:0001100,GO:0005575,GO:0005622,GO:0005623,GO:0005628,GO:0005737,GO:0005856,GO:0005874,GO:0005875,GO:0005881,GO:0005933,GO:0005934,GO:0005935,GO:0005937,GO:0005938,GO:0007049,GO:0007088,GO:0007096,GO:0007163,GO:0007346,GO:0008104,GO:0008150,GO:0008360,GO:0009987,GO:0010564,GO:0010639,GO:0010948,GO:0015630,GO:0016020,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022603,GO:0022604,GO:0030427,GO:0030428,GO:0031110,GO:0031111,GO:0031113,GO:0031115,GO:0031333,GO:0031500,GO:0032153,GO:0032155,GO:0032187,GO:0032231,GO:0032271,GO:0032272,GO:0032465,GO:0032505,GO:0032506,GO:0032878,GO:0032879,GO:0032886,GO:0032956,GO:0032970,GO:0032991,GO:0033036,GO:0033043,GO:0034613,GO:0035371,GO:0035838,GO:0035839,GO:0035840,GO:0036214,GO:0042763,GO:0042764,GO:0042995,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043332,GO:0044087,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044463,GO:0044464,GO:0044703,GO:0044764,GO:0045786,GO:0045839,GO:0045930,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051049,GO:0051128,GO:0051129,GO:0051179,GO:0051285,GO:0051286,GO:0051301,GO:0051302,GO:0051493,GO:0051494,GO:0051641,GO:0051704,GO:0051726,GO:0051783,GO:0051784,GO:0060627,GO:0061160,GO:0061172,GO:0061245,GO:0061246,GO:0061640,GO:0065007,GO:0065008,GO:0070507,GO:0070727,GO:0071944,GO:0071963,GO:0072697,GO:0090337,GO:0097427,GO:0099070,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099568,GO:0099738,GO:0110053,GO:0120025,GO:0120038,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902405,GO:1902410,GO:1902486,GO:1902903,GO:1902904,GO:1903047,GO:1904511,GO:1904758,GO:1990151,GO:1990615,GO:1990752,GO:1990778,GO:1990896,GO:2000099,GO:2000100,GO:2000114,GO:2000769,GO:2000771 - 0.00000000001296 78.0
CSH2_k127_5607407_3 Domain of unknown function (DUF4110) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000001219 65.0
CSH2_k127_561179_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 434.0
CSH2_k127_561179_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000001094 87.0
CSH2_k127_5616278_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1081.0
CSH2_k127_5616278_1 Bacterial transferase hexapeptide (six repeats) K00661 - 2.3.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000003323 254.0
CSH2_k127_5616278_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000004093 206.0
CSH2_k127_5616278_3 transcriptional regulator, AsnC family - - - 0.00000000000000000000000000000000000000000000000001994 185.0
CSH2_k127_5616278_4 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000003448 177.0
CSH2_k127_5630182_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000001651 81.0
CSH2_k127_5630182_1 Tetratricopeptide repeat - - - 0.0000005579 63.0
CSH2_k127_5647440_0 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 437.0
CSH2_k127_5647440_1 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000008821 185.0
CSH2_k127_5647440_2 pfam abc1 K03688 - - 0.0000000000000000000000000000004535 133.0
CSH2_k127_5664612_0 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001414 215.0
CSH2_k127_5664612_1 amine dehydrogenase activity K20276,K21430 - - 0.00000000000000002199 94.0
CSH2_k127_5671027_0 phosphoenolpyruvate carboxykinase (GTP) activity K01596,K01610 - 4.1.1.32,4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 419.0
CSH2_k127_5671027_1 CAAX protease self-immunity - - - 0.00000000000000000002342 106.0
CSH2_k127_5737027_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002279 262.0
CSH2_k127_5737456_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 382.0
CSH2_k127_5737456_1 COG3209 Rhs family protein - - - 0.00000008394 64.0
CSH2_k127_5755651_0 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 515.0
CSH2_k127_5762388_0 PFAM Phenylalanine and histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 381.0
CSH2_k127_5762388_1 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 354.0
CSH2_k127_5762388_2 Rad51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 324.0
CSH2_k127_5762388_3 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001947 263.0
CSH2_k127_5762388_4 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000000002034 185.0
CSH2_k127_5762388_6 Pfam:DUF1628 - - - 0.000000002972 65.0
CSH2_k127_5762388_7 Pfam:DUF1628 - - - 0.0002339 51.0
CSH2_k127_5824174_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000001983 243.0
CSH2_k127_5824174_1 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000004181 212.0
CSH2_k127_5824174_2 K homology RNA-binding domain K06961 - - 0.000000000000000000000000000000000000000000000008289 181.0
CSH2_k127_5824174_3 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000000000006772 141.0
CSH2_k127_5827246_0 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 349.0
CSH2_k127_5827246_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000004153 180.0
CSH2_k127_5827246_2 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000004451 64.0
CSH2_k127_5827840_0 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 462.0
CSH2_k127_5827840_1 Helix-turn-helix XRE-family like proteins K07728 - - 0.0000000000000000000009856 98.0
CSH2_k127_5827840_2 Belongs to the ABC transporter superfamily K02032 - - 0.00005724 46.0
CSH2_k127_5840397_0 Fibronectin type III domain - - - 0.00001453 57.0
CSH2_k127_5871308_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000369 237.0
CSH2_k127_5871308_1 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000245 170.0
CSH2_k127_5871308_2 Ribosomal S13/S15 N-terminal domain K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000007535 164.0
CSH2_k127_587583_0 Zinc carboxypeptidase family protein. Source PGD - - - 0.0000000000000000000001008 115.0
CSH2_k127_5880257_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 508.0
CSH2_k127_5893503_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000001713 267.0
CSH2_k127_591216_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 363.0
CSH2_k127_5957293_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 566.0
CSH2_k127_5957293_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000000000001547 151.0
CSH2_k127_5957293_2 Ras of Complex, Roc, domain of DAPkinase - - - 0.0000000000002312 73.0
CSH2_k127_5972441_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000001051 132.0
CSH2_k127_5988515_0 cellular response to DNA damage stimulus - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000000000000000000000000000000000000000000003679 195.0
CSH2_k127_5988515_1 Galactose oxidase, central domain K20285 - - 0.0004714 52.0
CSH2_k127_5992659_0 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 351.0
CSH2_k127_5992659_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 325.0
CSH2_k127_5992659_2 ADP-glyceromanno-heptose 6-epimerase activity K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000004033 269.0
CSH2_k127_5992659_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000001646 138.0
CSH2_k127_5992659_4 Right handed beta helix region - - - 0.0000000000000000000000001776 119.0
CSH2_k127_5992659_6 - - - - 0.00000002838 57.0
CSH2_k127_5992659_7 - - - - 0.000003812 51.0
CSH2_k127_6002323_0 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000002802 240.0
CSH2_k127_6002323_1 Protein of unknown function (DUF2797) - - - 0.00000000000001554 81.0
CSH2_k127_6011513_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000001008 161.0
CSH2_k127_6013247_0 AAA domain K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 611.0
CSH2_k127_6013247_1 Toprim domain K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 410.0
CSH2_k127_6013247_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 387.0
CSH2_k127_6013247_3 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006277 274.0
CSH2_k127_6013247_4 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000005701 180.0
CSH2_k127_6013247_6 protein related to plant photosystem II stability assembly factor - - - 0.0000005188 54.0
CSH2_k127_6013247_7 Roadblock/LC7 domain K07131 - - 0.000001146 56.0
CSH2_k127_6013247_8 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.0001026 48.0
CSH2_k127_6026110_0 ribosomal protein S3 K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003212 275.0
CSH2_k127_6026110_1 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001132 243.0
CSH2_k127_6026110_2 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000000472 183.0
CSH2_k127_6026110_3 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000404 161.0
CSH2_k127_6028307_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000002731 257.0
CSH2_k127_6028307_1 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.0000000000000000000000000000000000000000000002546 173.0
CSH2_k127_6028307_2 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000006782 139.0
CSH2_k127_6028307_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000000000003774 72.0
CSH2_k127_6037804_0 TIGRFAM Outer membrane protein K13735,K20276 - - 0.000000000000004833 89.0
CSH2_k127_6037804_1 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.00005227 57.0
CSH2_k127_6055075_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 373.0
CSH2_k127_6055075_1 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000002265 173.0
CSH2_k127_6055075_2 GTPase activity K07874 - - 0.000000000000000000000001456 109.0
CSH2_k127_6058320_0 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000003705 274.0
CSH2_k127_6058320_1 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000003691 192.0
CSH2_k127_6058320_2 - - - - 0.00000000000000000000000000000000000223 144.0
CSH2_k127_6058320_3 - - - - 0.0000000000000004479 80.0
CSH2_k127_6058320_4 NHL repeat containing protein - - - 0.000000000000002261 87.0
CSH2_k127_60615_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000002921 245.0
CSH2_k127_60615_1 TIGRFAM protein translocase SEC61 complex gamma subunit K07342 - - 0.00000000000004481 75.0
CSH2_k127_6063219_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 402.0
CSH2_k127_6063219_1 PFAM PKD domain containing protein - - - 0.0000000000000003654 94.0
CSH2_k127_6063219_2 CarboxypepD_reg-like domain - - - 0.000000000000007556 88.0
CSH2_k127_6063219_3 Peptidase S8 S53, subtilisin kexin sedolisin - - - 0.00001448 56.0
CSH2_k127_6076513_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 339.0
CSH2_k127_6076513_1 polygalacturonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006848 281.0
CSH2_k127_6083277_0 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000003147 209.0
CSH2_k127_6083277_1 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000001399 152.0
CSH2_k127_6083277_2 posttranscriptional regulation of gene expression K03113 - - 0.0000000000000000000000000000000001338 134.0
CSH2_k127_6083277_3 ribosomal protein L24 K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000009231 120.0
CSH2_k127_6083277_4 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001659 93.0
CSH2_k127_6083277_5 Ribosomal L29 protein K02904 - - 0.000000000000005412 77.0
CSH2_k127_6083277_6 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000001175 63.0
CSH2_k127_6118190_0 helicase superfamily c-terminal domain K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 416.0
CSH2_k127_6118190_1 SPFH domain-Band 7 family - - - 0.00001291 57.0
CSH2_k127_6119445_0 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000001841 203.0
CSH2_k127_6119445_1 toxin activity - - - 0.0000000000006978 73.0
CSH2_k127_6119445_2 - - - - 0.00000009069 57.0
CSH2_k127_6145970_0 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002288 259.0
CSH2_k127_6145970_1 cellulose binding - - - 0.000000004718 67.0
CSH2_k127_6174923_0 ATPase involved in DNA repair K03546 - - 0.000000000000000000000557 111.0
CSH2_k127_6187111_0 Glycosyl transferase 4-like - - - 0.00000000000000000519 93.0
CSH2_k127_6187224_0 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.00000000000000000000000000000000000000269 170.0
CSH2_k127_6187224_1 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.000000000000000000000001144 122.0
CSH2_k127_6187224_2 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.0000158 59.0
CSH2_k127_6214562_0 FMN binding - - - 0.0000000000000000000000000000000000000000000144 164.0
CSH2_k127_6214562_1 transcriptional - - - 0.00000000000000000000000000000001177 132.0
CSH2_k127_6214562_2 - - - - 0.000000001934 67.0
CSH2_k127_626566_0 Kelch motif - - - 0.000000000000000000000000000000000000009313 164.0
CSH2_k127_6273227_0 ArsR transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000001998 205.0
CSH2_k127_6273227_1 PFAM GvpD gas vesicle - - - 0.00000000000000000000000000000000000000000000000000004452 206.0
CSH2_k127_6273227_2 tetratricopeptide repeat - - - 0.000000000000000000000000000000000005579 150.0
CSH2_k127_6273227_3 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000003192 101.0
CSH2_k127_6273227_4 Roadblock LC7 family protein K07131 - - 0.000000000000000009738 89.0
CSH2_k127_6273227_5 - - - - 0.0000000000003074 74.0
CSH2_k127_6276199_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 312.0
CSH2_k127_6276199_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000002183 55.0
CSH2_k127_6282868_0 Helix-hairpin-helix motif K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000002353 224.0
CSH2_k127_6282868_1 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000002517 215.0
CSH2_k127_6282868_2 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000003845 112.0
CSH2_k127_6282868_3 RNA polymerase K03051 - 2.7.7.6 0.0000000000000000000002352 100.0
CSH2_k127_6286950_0 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000009327 113.0
CSH2_k127_6286950_1 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000005858 108.0
CSH2_k127_6286950_2 amine dehydrogenase activity - - - 0.000000001498 68.0
CSH2_k127_6308895_0 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 467.0
CSH2_k127_6308895_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 453.0
CSH2_k127_6308895_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 292.0
CSH2_k127_6308895_3 UbiA prenyltransferase family K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000004911 192.0
CSH2_k127_6308895_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000001599 170.0
CSH2_k127_6308895_5 Major facilitator superfamily - - - 0.0000004332 60.0
CSH2_k127_6308895_6 - - - - 0.000001777 55.0
CSH2_k127_6308895_7 ATPase-like protein K06915 - - 0.0003061 48.0
CSH2_k127_6309229_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 370.0
CSH2_k127_6309229_1 - - - - 0.00000000000000000000002 102.0
CSH2_k127_6309229_2 Protein of unknown function (DUF424) K09148 - - 0.000000000000000004665 89.0
CSH2_k127_6335704_0 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001222 305.0
CSH2_k127_6335704_1 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000002536 179.0
CSH2_k127_6335704_2 Thermophilic metalloprotease (M29) - - - 0.000000000189 72.0
CSH2_k127_6335704_3 - - - - 0.0001238 49.0
CSH2_k127_6335704_4 DUF167 K09131 - - 0.0004591 45.0
CSH2_k127_6355722_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003883 286.0
CSH2_k127_6377685_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 600.0
CSH2_k127_6377685_1 Catalyzes the conversion of dihydroorotate to orotate K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 311.0
CSH2_k127_6377685_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000006478 220.0
CSH2_k127_6377685_3 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.000004012 53.0
CSH2_k127_6390824_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 590.0
CSH2_k127_6435423_0 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 389.0
CSH2_k127_6435423_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 351.0
CSH2_k127_6435423_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 289.0
CSH2_k127_6435423_3 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000000001392 244.0
CSH2_k127_6440348_0 Purine nucleoside phosphorylase involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 334.0
CSH2_k127_6440348_1 Pectate lyase K21606 - 3.2.1.202 0.0000000000000000000000000000000000001986 158.0
CSH2_k127_6440348_2 Phosphoribosyl transferase domain K00769,K07101 - 2.4.2.22 0.0000000008652 61.0
CSH2_k127_6440348_3 N-Acetylmuramoyl-L-alanine amidase K01176,K01448 GO:0003674,GO:0005198,GO:0005199,GO:0005575,GO:0005623,GO:0008150,GO:0009273,GO:0009987,GO:0030115,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 3.2.1.1,3.5.1.28 0.000001428 61.0
CSH2_k127_6461745_0 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000001796 135.0
CSH2_k127_6470932_0 serine threonine protein kinase - - - 0.00000000006609 76.0
CSH2_k127_6517871_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 3.524e-211 666.0
CSH2_k127_6517871_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000001127 209.0
CSH2_k127_6517871_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000001645 188.0
CSH2_k127_6517871_3 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000001762 180.0
CSH2_k127_6517871_4 - - - - 0.0000000000000000000000003607 112.0
CSH2_k127_6517871_5 Pheromone shutdown protein - - - 0.0000000000000000000000008121 113.0
CSH2_k127_6517871_6 metallopeptidase activity - - - 0.000000002347 69.0
CSH2_k127_6539454_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 371.0
CSH2_k127_6539454_1 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001099 231.0
CSH2_k127_6539454_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000002581 84.0
CSH2_k127_6539454_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000002326 51.0
CSH2_k127_6540285_0 Related to alanyl-tRNA synthetase HxxxH domain K01872,K07050 GO:0002161,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000005039 246.0
CSH2_k127_6540285_1 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000004975 171.0
CSH2_k127_6549859_0 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000003812 160.0
CSH2_k127_6549859_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000006341 83.0
CSH2_k127_6549859_2 - - - - 0.0000000000002377 81.0
CSH2_k127_6552643_0 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 406.0
CSH2_k127_6552643_1 PFAM TonB-dependent Receptor K16091 - - 0.00001154 58.0
CSH2_k127_6552643_2 Protein of unknown function (DUF1015) - - - 0.0002643 43.0
CSH2_k127_6577763_0 Peptidase M14, carboxypeptidase A K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000000007974 186.0
CSH2_k127_6577763_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000004248 156.0
CSH2_k127_6577763_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000001239 89.0
CSH2_k127_6577909_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 375.0
CSH2_k127_6577909_1 nucleotidyltransferase activity - - - 0.00000000000002403 75.0
CSH2_k127_6584972_0 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 374.0
CSH2_k127_6584972_1 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000438 246.0
CSH2_k127_6584972_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000001846 135.0
CSH2_k127_6584972_3 Electron transfer flavoprotein FAD-binding domain K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0002758 45.0
CSH2_k127_6639429_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 382.0
CSH2_k127_6639429_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.0000000000000000000000001831 114.0
CSH2_k127_6639429_2 radical SAM domain protein - - - 0.000000000000000007103 85.0
CSH2_k127_6650620_0 KaiC - - - 0.0000000000000000000000000000000008179 144.0
CSH2_k127_6650620_1 KaiC - - - 0.00000000000000000008124 100.0
CSH2_k127_6681929_0 Prenyltransferase K13277 - - 0.00000000000000000000002074 117.0
CSH2_k127_6681929_1 Endonuclease Exonuclease Phosphatase - - - 0.0001065 56.0
CSH2_k127_6693020_0 VTC domain - - - 0.000000000000000000000000000000000000000000000000000000000001367 217.0
CSH2_k127_6693020_1 Domain of unknown function (DUF4956) - - - 0.000000000000000000000000000000000000000000000001456 181.0
CSH2_k127_6693020_2 PFAM PKD domain containing protein - - - 0.00000002373 60.0
CSH2_k127_6693020_3 acid phosphatase activity - - - 0.00003416 54.0
CSH2_k127_6710611_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 417.0
CSH2_k127_6710611_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0000000000000000000000000000000000000000000003137 171.0
CSH2_k127_6731146_0 DALR anticodon binding domain K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 419.0
CSH2_k127_6739608_0 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000003364 228.0
CSH2_k127_6739608_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000001528 82.0
CSH2_k127_6739608_2 Signal peptidase K13280 - 3.4.21.89 0.0000000000000001372 93.0
CSH2_k127_6746117_0 von Willebrand factor, type A K07114 - - 0.00000000000000000000421 111.0
CSH2_k127_6746117_1 Belongs to the peptidase S8 family K08651,K14645 - 3.4.21.66 0.0000312 59.0
CSH2_k127_6746117_2 glucose sorbosone - - - 0.0004863 55.0
CSH2_k127_6748694_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 462.0
CSH2_k127_6748694_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000002305 177.0
CSH2_k127_6748694_2 Fibronectin type III domain - - - 0.00000000000000000001684 100.0
CSH2_k127_6763185_0 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 394.0
CSH2_k127_6763185_1 Uncharacterised protein family (UPF0179) K09730 - - 0.0000000000000000000000000001441 117.0
CSH2_k127_6763185_2 PFAM regulatory protein, ArsR - - - 0.000000000002575 76.0
CSH2_k127_698342_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 480.0
CSH2_k127_719773_0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000001717 212.0
CSH2_k127_719773_1 Succinoglycan biosynthesis protein exoa - - - 0.00000000000000000000001045 112.0
CSH2_k127_728737_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000001531 229.0
CSH2_k127_728737_1 AAA domain - - - 0.0000009393 58.0
CSH2_k127_785651_0 ABC transporter K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 327.0
CSH2_k127_785651_1 PFAM GvpD gas vesicle - - - 0.0000000000000000004064 101.0
CSH2_k127_789385_0 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006084 277.0
CSH2_k127_789385_1 Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000001122 190.0
CSH2_k127_789385_2 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000521 111.0
CSH2_k127_843598_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.49e-201 646.0
CSH2_k127_856621_0 PFAM Aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 338.0
CSH2_k127_856621_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000002217 154.0
CSH2_k127_856621_2 Domain of unknown function (DUF1610) K07580 - - 0.000000000000000000666 87.0
CSH2_k127_856621_3 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000006549 82.0
CSH2_k127_856621_4 AAA domain - - - 0.0000000165 59.0
CSH2_k127_856621_5 Polysaccharide biosynthesis protein - - - 0.0003759 52.0
CSH2_k127_882229_0 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000002669 232.0
CSH2_k127_882229_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000001106 228.0
CSH2_k127_882229_2 - - - - 0.0000000000000000000001621 104.0
CSH2_k127_882229_3 - K00960 - 2.7.7.6 0.0000000000000000003495 87.0
CSH2_k127_914133_0 PFAM DNA alkylation repair enzyme - - - 0.000000244 61.0
CSH2_k127_914133_1 Parallel beta-helix repeats - - - 0.000002308 62.0
CSH2_k127_914133_2 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.00004764 57.0
CSH2_k127_92304_0 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000031 206.0
CSH2_k127_92304_1 Right handed beta helix region - - - 0.00000000000000002685 94.0
CSH2_k127_928397_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000008879 219.0
CSH2_k127_928397_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000002815 103.0
CSH2_k127_928397_2 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0001297 52.0
CSH2_k127_935244_0 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 326.0
CSH2_k127_935244_1 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 295.0
CSH2_k127_935244_2 binds to the 23S rRNA K02921 - - 0.0000000000000000003015 91.0
CSH2_k127_935244_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000131 78.0
CSH2_k127_935244_4 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.0000000005207 63.0
CSH2_k127_935244_5 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0001373 48.0
CSH2_k127_951149_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000003736 224.0
CSH2_k127_951149_1 - - - - 0.0000000000000000000000000000000000002913 149.0
CSH2_k127_951149_2 PFAM DEAD_2 domain protein K10844 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0043139,GO:0048037,GO:0051276,GO:0051536,GO:0051539,GO:0051540,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 0.00000001549 61.0
CSH2_k127_989696_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003704 268.0
CSH2_k127_989696_1 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000001592 162.0
CSH2_k127_989696_2 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000005488 157.0
CSH2_k127_989696_3 Sugar efflux transporter for intercellular exchange K15383 - - 0.00000000000000004358 84.0
CSH2_k127_993877_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 417.0
CSH2_k127_993877_1 - - - - 0.0000411 52.0