Overview

ID MAG00617
Name CSH2_bin.35
Sample SMP0014
Taxonomy
Kingdom Bacteria
Phylum Verrucomicrobiota
Class Verrucomicrobiia
Order Limisphaerales
Family DSYF01
Genus JALOTU01
Species JALOTU01 sp025457615
Assembly information
Completeness (%) 54.39
Contamination (%) 0.76
GC content (%) 64.0
N50 (bp) 5,086
Genome size (bp) 1,649,209

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1426

Gene name Description KEGG GOs EC E-value Score Sequence
CSH2_k127_1011697_0 5TM C-terminal transporter carbon starvation CstA - - - 1.181e-292 918.0
CSH2_k127_1011697_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 6.367e-220 700.0
CSH2_k127_1011697_2 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 318.0
CSH2_k127_1011697_3 protein involved in formation of curli polymers - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 293.0
CSH2_k127_1011697_4 Putative bacterial lipoprotein (DUF799) - - - 0.00000000000000000000000000000000000000000000000000000000001513 212.0
CSH2_k127_1011697_5 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000002536 174.0
CSH2_k127_1011697_6 - - - - 0.000000000000000000000000000000000004313 143.0
CSH2_k127_1011697_7 Lipoprotein - - - 0.00000000000000000000004192 104.0
CSH2_k127_1011697_8 Polysaccharide biosynthesis protein - - - 0.00000002091 64.0
CSH2_k127_1011971_0 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000685 269.0
CSH2_k127_1011971_1 - - - - 0.0000000000000000000000000000000000000001325 167.0
CSH2_k127_1011971_2 - - - - 0.00000000000000000000000000000002934 135.0
CSH2_k127_1011971_3 Mechanosensitive ion channel - - - 0.00000000000000000000000000002969 122.0
CSH2_k127_1011971_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000001146 109.0
CSH2_k127_1048174_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 538.0
CSH2_k127_1048174_1 Domains in Na-Ca exchangers and integrin-beta4 K01406 - 3.4.24.40 0.00000000000000000000000000000005839 145.0
CSH2_k127_1048174_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000001779 107.0
CSH2_k127_1048174_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000007742 111.0
CSH2_k127_1048174_4 tetratricopeptide repeat - - - 0.0000000002263 74.0
CSH2_k127_1048174_6 Intraflagellar transport protein 88 K16474 GO:0000003,GO:0000226,GO:0000902,GO:0000904,GO:0001578,GO:0001654,GO:0001655,GO:0001669,GO:0001822,GO:0001885,GO:0001886,GO:0001889,GO:0001944,GO:0002064,GO:0002080,GO:0002081,GO:0002119,GO:0002164,GO:0003002,GO:0003006,GO:0003007,GO:0003008,GO:0003158,GO:0003205,GO:0003206,GO:0003279,GO:0003382,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005802,GO:0005813,GO:0005814,GO:0005815,GO:0005856,GO:0005929,GO:0005930,GO:0006810,GO:0006928,GO:0006950,GO:0006970,GO:0006996,GO:0006997,GO:0007010,GO:0007017,GO:0007018,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0007224,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007288,GO:0007289,GO:0007290,GO:0007368,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007423,GO:0007507,GO:0007600,GO:0007605,GO:0007610,GO:0007626,GO:0008092,GO:0008104,GO:0008150,GO:0008283,GO:0008285,GO:0008544,GO:0008589,GO:0009628,GO:0009653,GO:0009790,GO:0009791,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009894,GO:0009952,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010506,GO:0010646,GO:0010647,GO:0010970,GO:0012505,GO:0012506,GO:0014706,GO:0015630,GO:0016020,GO:0016043,GO:0016241,GO:0019222,GO:0019894,GO:0019953,GO:0021510,GO:0021511,GO:0021513,GO:0021537,GO:0022008,GO:0022412,GO:0022414,GO:0022603,GO:0022607,GO:0022611,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030031,GO:0030141,GO:0030154,GO:0030162,GO:0030182,GO:0030317,GO:0030323,GO:0030324,GO:0030326,GO:0030659,GO:0030667,GO:0030705,GO:0030855,GO:0030900,GO:0030990,GO:0030992,GO:0031016,GO:0031090,GO:0031122,GO:0031175,GO:0031323,GO:0031329,GO:0031344,GO:0031410,GO:0031503,GO:0031514,GO:0031982,GO:0031984,GO:0032101,GO:0032103,GO:0032391,GO:0032421,GO:0032501,GO:0032502,GO:0032504,GO:0032838,GO:0032989,GO:0032991,GO:0033036,GO:0033043,GO:0034405,GO:0035051,GO:0035082,GO:0035107,GO:0035108,GO:0035113,GO:0035295,GO:0035640,GO:0035641,GO:0035735,GO:0035869,GO:0036064,GO:0036334,GO:0040011,GO:0040012,GO:0040017,GO:0040024,GO:0042073,GO:0042127,GO:0042481,GO:0042487,GO:0042490,GO:0042592,GO:0042692,GO:0042733,GO:0042995,GO:0043005,GO:0043053,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043567,GO:0043568,GO:0043583,GO:0044085,GO:0044087,GO:0044088,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044431,GO:0044433,GO:0044441,GO:0044444,GO:0044446,GO:0044447,GO:0044450,GO:0044463,GO:0044464,GO:0044703,GO:0044782,GO:0045446,GO:0045595,GO:0045598,GO:0046907,GO:0048232,GO:0048468,GO:0048513,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048645,GO:0048646,GO:0048666,GO:0048699,GO:0048731,GO:0048732,GO:0048736,GO:0048738,GO:0048839,GO:0048853,GO:0048854,GO:0048856,GO:0048869,GO:0048870,GO:0048872,GO:0050678,GO:0050680,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050877,GO:0050896,GO:0050920,GO:0050921,GO:0050954,GO:0051128,GO:0051146,GO:0051171,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051716,GO:0055007,GO:0055115,GO:0060021,GO:0060091,GO:0060113,GO:0060119,GO:0060122,GO:0060173,GO:0060255,GO:0060259,GO:0060271,GO:0060322,GO:0060411,GO:0060426,GO:0060429,GO:0060491,GO:0060537,GO:0060541,GO:0060914,GO:0061008,GO:0061061,GO:0061351,GO:0065007,GO:0065008,GO:0070613,GO:0070925,GO:0071840,GO:0072001,GO:0072358,GO:0072359,GO:0080090,GO:0090102,GO:0097014,GO:0097223,GO:0097435,GO:0097458,GO:0097541,GO:0097542,GO:0097546,GO:0097708,GO:0097722,GO:0097730,GO:0097731,GO:0097732,GO:0097733,GO:0098588,GO:0098589,GO:0098791,GO:0098805,GO:0098862,GO:0099111,GO:0099503,GO:0099568,GO:0120025,GO:0120031,GO:0120032,GO:0120035,GO:0120036,GO:0120038,GO:1902017,GO:1902115,GO:1903317,GO:1903929,GO:1905515,GO:2000026,GO:2000027,GO:2000785 - 0.0005558 53.0
CSH2_k127_1048233_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 307.0
CSH2_k127_1048233_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 290.0
CSH2_k127_1048233_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000008802 219.0
CSH2_k127_1048233_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000663 173.0
CSH2_k127_1048233_4 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000005305 149.0
CSH2_k127_1060608_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000002496 253.0
CSH2_k127_1060608_1 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000004455 231.0
CSH2_k127_1063512_0 arginine decarboxylase K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 398.0
CSH2_k127_1063512_1 Conserved TM helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 315.0
CSH2_k127_1063512_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000008745 238.0
CSH2_k127_1078412_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.287e-197 640.0
CSH2_k127_1129005_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 308.0
CSH2_k127_1129005_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000212 166.0
CSH2_k127_1129005_2 Met-10+ like-protein K02687 - - 0.00000000000000000000000000000000000004908 157.0
CSH2_k127_1129005_3 alpha-ribazole phosphatase activity K02226,K15634,K15640,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.000000000000000000000000001309 120.0
CSH2_k127_1160580_0 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 497.0
CSH2_k127_1166756_0 Trypsin - - - 5.641e-227 722.0
CSH2_k127_1166756_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 550.0
CSH2_k127_1166756_2 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000002083 170.0
CSH2_k127_1174642_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 452.0
CSH2_k127_1174642_1 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 439.0
CSH2_k127_1174642_2 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 413.0
CSH2_k127_1174642_3 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 372.0
CSH2_k127_1174642_4 galactose-1-phosphate uridylyltransferase K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.0000000000000000000000000001119 122.0
CSH2_k127_1182832_0 PFAM Alpha amylase, catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001443 275.0
CSH2_k127_1191759_0 TIGRFAM RHS repeat-associated core domain - - - 0.0000000000000000000000000000000000000000000000000000000000003536 242.0
CSH2_k127_1191759_1 PFAM Transposase IS200 like - - - 0.0000000003237 61.0
CSH2_k127_1204898_0 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000003067 175.0
CSH2_k127_1204898_1 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000001663 170.0
CSH2_k127_1204898_2 PFAM IS66 Orf2 family protein K07484 - - 0.0000000000000000000000000000000000000000009633 166.0
CSH2_k127_1204898_3 - - - - 0.0000004509 57.0
CSH2_k127_1232694_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 473.0
CSH2_k127_1232694_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 309.0
CSH2_k127_1232694_2 family 9 - - - 0.00000000007591 74.0
CSH2_k127_1232694_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.297 0.000000004202 59.0
CSH2_k127_1236528_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.954e-242 766.0
CSH2_k127_1257595_0 PFAM ABC transporter related K06158 - - 5.027e-203 650.0
CSH2_k127_1257595_1 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 568.0
CSH2_k127_1257595_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 531.0
CSH2_k127_1257595_3 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.000000000000000000000000000006114 130.0
CSH2_k127_1257595_4 Transcriptional regulator - - - 0.00000000000000000006135 101.0
CSH2_k127_1257595_5 - - - - 0.0000000000000001689 88.0
CSH2_k127_1273388_0 COGs COG2993 Cbb3-type cytochrome oxidase cytochrome c subunit K00405 - - 0.0000000000000000000000000000000000009864 150.0
CSH2_k127_1273388_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000002642 138.0
CSH2_k127_1273388_2 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 0.000000000000000000001708 106.0
CSH2_k127_1289033_0 Belongs to the GTP cyclohydrolase I type 2 NIF3 family K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 294.0
CSH2_k127_1289033_1 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000009582 193.0
CSH2_k127_1289033_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000008252 175.0
CSH2_k127_1289033_3 Putative transposase - - - 0.0000000000000000008844 92.0
CSH2_k127_1289033_4 PFAM Methyltransferase type 11 - - - 0.000000000000000003827 94.0
CSH2_k127_1289033_5 - - - - 0.00000000000000287 76.0
CSH2_k127_1289033_6 SNAP receptor activity - - - 0.000000002867 67.0
CSH2_k127_134935_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009783 430.0
CSH2_k127_134935_1 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 311.0
CSH2_k127_134935_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000001109 236.0
CSH2_k127_134935_3 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000003188 239.0
CSH2_k127_1410521_0 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 383.0
CSH2_k127_1410521_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000006475 213.0
CSH2_k127_1410521_2 Beta galactosidase small chain K01190 GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494 3.2.1.23 0.00000000000000000003635 102.0
CSH2_k127_1410521_3 - - - - 0.00000000000000007926 82.0
CSH2_k127_1416614_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 393.0
CSH2_k127_1416614_1 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000003572 274.0
CSH2_k127_141777_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 604.0
CSH2_k127_141777_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 362.0
CSH2_k127_141777_2 of the major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000007295 245.0
CSH2_k127_141777_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000003082 219.0
CSH2_k127_1428876_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000002253 251.0
CSH2_k127_1428876_1 integral membrane protein - - - 0.000000000000000000006768 104.0
CSH2_k127_1428876_2 Protein of unknown function (DUF2752) - - - 0.0000000000000000004923 94.0
CSH2_k127_1428876_3 RDD family K18481 - - 0.00000003391 64.0
CSH2_k127_1444058_0 ABC transporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 492.0
CSH2_k127_1444058_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 469.0
CSH2_k127_1444058_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 373.0
CSH2_k127_1444058_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 314.0
CSH2_k127_1444058_4 protein deglycation K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000006471 221.0
CSH2_k127_1444058_5 Maf-like protein - - - 0.000000000000000000000000000000000000003694 152.0
CSH2_k127_1444058_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000007527 137.0
CSH2_k127_1444058_7 SdrD B-like domain - - - 0.00000000000000000000000000001688 121.0
CSH2_k127_1444058_8 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000004958 121.0
CSH2_k127_1444058_9 Domain of unknown function (DUF4410) - - - 0.000000000000000000000000005546 120.0
CSH2_k127_1444144_0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 475.0
CSH2_k127_1444144_1 rRNA (cytosine-C5-)-methyltransferase activity K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 364.0
CSH2_k127_1444144_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000001082 161.0
CSH2_k127_1444144_3 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000003718 104.0
CSH2_k127_1444144_4 Domain of unknown function (DUF4136) - - - 0.00000000000000156 81.0
CSH2_k127_1444144_5 elongation factor G - - - 0.00000000001037 72.0
CSH2_k127_145790_0 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000003397 253.0
CSH2_k127_145790_1 PFAM General secretion pathway protein K K02460 - - 0.000000000000001419 89.0
CSH2_k127_145790_2 response regulator K02483 - - 0.000000000000711 72.0
CSH2_k127_145790_3 Type II secretion system (T2SS), protein J K02459 - - 0.000009606 57.0
CSH2_k127_145790_4 Prokaryotic N-terminal methylation motif K02458 - - 0.0001357 50.0
CSH2_k127_1487542_0 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 2.075e-200 645.0
CSH2_k127_1487542_1 Alpha amylase, catalytic domain K16147 - 2.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 334.0
CSH2_k127_1487542_2 Maltogenic Amylase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005838 301.0
CSH2_k127_1487542_3 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000000000000472 228.0
CSH2_k127_1487542_4 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000002188 218.0
CSH2_k127_1487542_5 Histidine kinase - - - 0.000000000000000000000000000000000000000002513 176.0
CSH2_k127_1487542_6 Carbohydrate binding domain - - - 0.0000000000000008756 90.0
CSH2_k127_1492836_0 PFAM Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 301.0
CSH2_k127_1492836_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000002834 237.0
CSH2_k127_1492836_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000004194 217.0
CSH2_k127_1492836_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000006196 180.0
CSH2_k127_1492836_4 Protein of unknown function (DUF2851) - - - 0.00000000000000000000000000000000000000004929 164.0
CSH2_k127_1529708_0 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 322.0
CSH2_k127_1529708_1 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000001137 205.0
CSH2_k127_1529708_2 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000001776 130.0
CSH2_k127_1536229_0 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000002297 167.0
CSH2_k127_1536229_1 PFAM Proprotein convertase P-domain - - - 0.00000000000000000000000000000000003841 148.0
CSH2_k127_1552611_0 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 354.0
CSH2_k127_1552611_1 photoreceptor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 321.0
CSH2_k127_1552611_2 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004946 274.0
CSH2_k127_1552611_3 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000003233 177.0
CSH2_k127_1552611_4 - - - - 0.0000000000000000000000000000000000000008462 153.0
CSH2_k127_1552611_5 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000002829 149.0
CSH2_k127_1570568_0 Glycosyl transferase family group 2 K03669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 486.0
CSH2_k127_1570568_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000292 168.0
CSH2_k127_1570568_2 Bacterial PH domain - - - 0.0001126 49.0
CSH2_k127_1620556_0 DEAD-like helicases superfamily K07012 - - 0.00000000000000000000000003542 113.0
CSH2_k127_1620556_2 - - - - 0.00000000000000000002261 104.0
CSH2_k127_1620556_4 PFAM CRISPR-associated protein, GSU0054 family (Cas_GSU0054) K19132 - - 0.00000009628 60.0
CSH2_k127_1632052_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 6.038e-241 754.0
CSH2_k127_1632052_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 477.0
CSH2_k127_1632052_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 396.0
CSH2_k127_1632052_3 COG2133 Glucose sorbosone dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000008937 261.0
CSH2_k127_1632052_4 transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000004816 169.0
CSH2_k127_1632052_5 anaphase-promoting complex binding - - - 0.00000001619 61.0
CSH2_k127_1678846_0 Beta-Casp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 369.0
CSH2_k127_1678846_1 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005691 254.0
CSH2_k127_1678846_2 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000006389 128.0
CSH2_k127_1678846_3 RNA-directed DNA polymerase (reverse transcriptase) - - - 0.000000000000002226 76.0
CSH2_k127_169190_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 4.688e-212 675.0
CSH2_k127_169190_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 501.0
CSH2_k127_169190_2 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 426.0
CSH2_k127_169190_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000005432 218.0
CSH2_k127_169190_4 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000000000000002411 153.0
CSH2_k127_1697468_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 2.059e-214 672.0
CSH2_k127_1697468_1 Domain of unknown function DUF11 - - - 5.504e-208 672.0
CSH2_k127_1697468_2 Glutamate synthase K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 569.0
CSH2_k127_1697468_3 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 494.0
CSH2_k127_1697468_4 general secretion pathway protein D K02453 - - 0.00000000000000000000000000000000000000000001398 186.0
CSH2_k127_1729723_0 SMART helicase c2 K03722 - 3.6.4.12 8.217e-230 732.0
CSH2_k127_1729723_1 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000008582 267.0
CSH2_k127_1729723_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000092 273.0
CSH2_k127_1739178_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002043 306.0
CSH2_k127_1739178_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002842 279.0
CSH2_k127_1739178_2 - - - - 0.00000000000000001483 85.0
CSH2_k127_1747361_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.549e-238 748.0
CSH2_k127_1747361_1 GHMP kinase, N-terminal domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 523.0
CSH2_k127_1747361_2 DNA ligase N terminus K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 317.0
CSH2_k127_1747361_3 RNase_H superfamily K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000004854 236.0
CSH2_k127_1747361_4 Permease MlaE K02066 - - 0.0000000000000000000000000000154 129.0
CSH2_k127_1747361_5 ABC transporter K02065 - - 0.0000000000000000000000001205 120.0
CSH2_k127_1747361_6 MlaD protein K02067 - - 0.00001272 57.0
CSH2_k127_1766625_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 7.359e-237 754.0
CSH2_k127_1766625_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 509.0
CSH2_k127_1766625_2 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006718 276.0
CSH2_k127_1766625_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000008071 190.0
CSH2_k127_1766625_4 TIGRFAM TIGR03790 family protein - - - 0.000000000000000000000000000000009976 148.0
CSH2_k127_1766625_5 regulator of chromosome condensation, RCC1 K20276 - - 0.0000000000000000007701 97.0
CSH2_k127_1766625_6 PEP-CTERM motif - - - 0.000000006974 66.0
CSH2_k127_1768488_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 323.0
CSH2_k127_1768488_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000001348 182.0
CSH2_k127_1770522_0 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 349.0
CSH2_k127_1770522_1 Belongs to the glutamate synthase family K00467 - 1.13.12.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002067 290.0
CSH2_k127_1770522_2 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000001743 205.0
CSH2_k127_1770522_3 PFAM YD repeat-containing protein - - - 0.000000000000002711 80.0
CSH2_k127_1792555_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 302.0
CSH2_k127_1792555_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000001379 230.0
CSH2_k127_1792555_2 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000004646 101.0
CSH2_k127_1792555_3 Domain of Unknown Function (DUF748) - - - 0.00000000004335 68.0
CSH2_k127_1804517_0 Integrin alpha (beta-propellor repeats). - - - 0.0000000000000000000000000000000000000000000000000000000003132 225.0
CSH2_k127_1804517_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000004003 165.0
CSH2_k127_1804517_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000007802 153.0
CSH2_k127_1804517_3 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000001612 112.0
CSH2_k127_1804517_4 Uncharacterised protein family UPF0047 - - - 0.000007581 49.0
CSH2_k127_1835083_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009672 291.0
CSH2_k127_1848543_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 544.0
CSH2_k127_1848543_1 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000125 177.0
CSH2_k127_1848543_2 Glycosyl transferase family group 2 - - - 0.0000000000000000001578 100.0
CSH2_k127_1859687_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 357.0
CSH2_k127_1859687_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 327.0
CSH2_k127_1859687_2 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067,K06192 - - 0.00000000000000000000000000000000000000000001054 175.0
CSH2_k127_1859687_3 DNA / pantothenate metabolism flavoprotein K21977 - 6.3.2.5 0.0000000000000000000000000000000003237 138.0
CSH2_k127_1859687_4 Protein conserved in bacteria K09857 - - 0.0000000004233 72.0
CSH2_k127_1859687_5 COG0286 Type I restriction-modification system K03427 - 2.1.1.72 0.000003845 55.0
CSH2_k127_1878050_0 Penicillin binding protein transpeptidase domain K03587,K08384 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 378.0
CSH2_k127_1878050_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 355.0
CSH2_k127_1878050_10 Protein of unknown function (DUF541) K09797 - - 0.0000000000000000000000000000000000000000000588 169.0
CSH2_k127_1878050_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000114 142.0
CSH2_k127_1878050_12 PFAM LysM domain - - - 0.00000000000000001486 92.0
CSH2_k127_1878050_13 Cell division protein FtsQ K03589 - - 0.000000003989 67.0
CSH2_k127_1878050_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 346.0
CSH2_k127_1878050_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 341.0
CSH2_k127_1878050_4 Mur ligase family, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 307.0
CSH2_k127_1878050_5 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 303.0
CSH2_k127_1878050_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001455 286.0
CSH2_k127_1878050_7 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003327 278.0
CSH2_k127_1878050_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000007289 235.0
CSH2_k127_1878050_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000003488 199.0
CSH2_k127_1895533_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 493.0
CSH2_k127_1895533_1 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 381.0
CSH2_k127_1895533_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000004099 183.0
CSH2_k127_1895533_3 PFAM amino acid-binding ACT domain protein - - - 0.00000000007052 70.0
CSH2_k127_1896219_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 589.0
CSH2_k127_1896219_1 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 575.0
CSH2_k127_1896219_2 Nucleoside diphosphate kinase K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 473.0
CSH2_k127_1896219_3 NUDIX domain K03574,K03575 - 3.6.1.55 0.0000000000000000000000000002477 122.0
CSH2_k127_1896219_4 - - - - 0.0000000004252 62.0
CSH2_k127_1896219_5 Tetratricopeptide repeat - - - 0.0002536 51.0
CSH2_k127_1939052_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 503.0
CSH2_k127_1939052_1 Prepilin-type N-terminal cleavage methylation domain - - - 0.00000000001586 74.0
CSH2_k127_1939052_2 nuclear chromosome segregation - - - 0.000000001289 72.0
CSH2_k127_1939052_3 Outer membrane efflux protein K12340 - - 0.00000004277 57.0
CSH2_k127_1939052_4 Regulatory protein, FmdB family - - - 0.000003812 51.0
CSH2_k127_1973346_0 pathogenesis K18286,K20276 - 3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 528.0
CSH2_k127_1973346_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006604 278.0
CSH2_k127_1982036_0 ATPases associated with a variety of cellular activities K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000227 273.0
CSH2_k127_1982036_1 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006526 272.0
CSH2_k127_1982036_2 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000007426 241.0
CSH2_k127_1982036_3 Permease MlaE - - - 0.00000000000000000000000000000000000000000000000000000000000000002128 235.0
CSH2_k127_1982036_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000001247 227.0
CSH2_k127_1982036_5 MlaD protein K02067 - - 0.0001139 54.0
CSH2_k127_1982036_6 Putative prokaryotic signal transducing protein - - - 0.0001669 51.0
CSH2_k127_1984202_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1429.0
CSH2_k127_1984202_1 F5/8 type C domain - - - 0.0 1408.0
CSH2_k127_1984202_10 TIGRFAM TIGR03790 family protein - - - 0.000000000000000000000000000000004486 149.0
CSH2_k127_1984202_11 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000837 132.0
CSH2_k127_1984202_12 - - - - 0.00000000000000000000000000002258 132.0
CSH2_k127_1984202_13 - - - - 0.00000000000001056 84.0
CSH2_k127_1984202_14 Dihaem cytochrome c - - - 0.000355 46.0
CSH2_k127_1984202_2 MFS/sugar transport protein K16211 - - 5.094e-224 704.0
CSH2_k127_1984202_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 558.0
CSH2_k127_1984202_4 threonine synthase activity K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 513.0
CSH2_k127_1984202_5 Anticodon binding domain K01880 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 391.0
CSH2_k127_1984202_6 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 349.0
CSH2_k127_1984202_7 HAMP domain K07640 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 357.0
CSH2_k127_1984202_8 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003663 270.0
CSH2_k127_1984202_9 Glycosyl hydrolase family 65, C-terminal domain K00691,K01087,K01194,K01838,K03731,K05342 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008801,GO:0009058,GO:0009292,GO:0009294,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016853,GO:0016866,GO:0016868,GO:0019203,GO:0030312,GO:0033554,GO:0034637,GO:0040007,GO:0042221,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046351,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0071704,GO:0071944,GO:1901576 2.4.1.216,2.4.1.64,2.4.1.8,3.1.3.12,3.2.1.28,5.4.2.6 0.00000000000000000000000000000000000000000000001141 176.0
CSH2_k127_2011603_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.219e-246 771.0
CSH2_k127_2011603_1 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 612.0
CSH2_k127_2011603_2 ResB-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009921 352.0
CSH2_k127_2011603_3 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001679 259.0
CSH2_k127_2011603_4 - - - - 0.0000000000000000000000000000000000000634 156.0
CSH2_k127_2024773_0 Belongs to the glycosyl hydrolase 13 family K01176 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001521 271.0
CSH2_k127_2024773_1 glycoside hydrolase, family 13 domain protein K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000002746 208.0
CSH2_k127_2024773_2 lipolytic protein G-D-S-L family K00612 - - 0.0000000000000000003615 103.0
CSH2_k127_2024773_3 general secretion pathway protein K02456,K02679 - - 0.00000000000007317 83.0
CSH2_k127_2024773_4 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000000003447 79.0
CSH2_k127_2024773_5 chaperone-mediated protein folding - - - 0.00000386 51.0
CSH2_k127_2024773_6 self proteolysis - - - 0.00001259 57.0
CSH2_k127_2024773_7 lipolytic protein G-D-S-L family K00612 - - 0.0004608 48.0
CSH2_k127_2037846_0 Aldo/keto reductase family K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 551.0
CSH2_k127_2037846_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 412.0
CSH2_k127_2037846_2 Thioesterase superfamily - - - 0.0000000000000000000000000000027 126.0
CSH2_k127_2052125_0 PFAM Acetyl-CoA hydrolase transferase - - - 1.474e-258 810.0
CSH2_k127_2052125_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 6.062e-242 772.0
CSH2_k127_2052125_2 Psort location CytoplasmicMembrane, score 10.00 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 537.0
CSH2_k127_2052125_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 344.0
CSH2_k127_2056555_0 DisA bacterial checkpoint controller nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000001941 202.0
CSH2_k127_2056555_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.000000000000000007208 85.0
CSH2_k127_2090020_0 PFAM nickel-dependent hydrogenase large subunit K00436 - 1.12.1.2 3.177e-223 700.0
CSH2_k127_2090020_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K05587 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 519.0
CSH2_k127_2090020_2 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K05588 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 356.0
CSH2_k127_2090020_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000001388 214.0
CSH2_k127_2090020_4 TIGRFAM hydrogenase maturation protease - - - 0.00000000000000000000000001161 117.0
CSH2_k127_2090576_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000002794 234.0
CSH2_k127_2090576_1 Psort location Extracellular, score - - - 0.0000000000000000000000000000000000000000000000000000000000000001163 229.0
CSH2_k127_2090576_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000003166 224.0
CSH2_k127_2090576_3 MgtC family - - - 0.000000000000000000000000000000000000000000000000000004456 200.0
CSH2_k127_2090576_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000464 137.0
CSH2_k127_2090576_5 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000004264 138.0
CSH2_k127_2090576_6 - - - - 0.00000000000000000000000000000002034 131.0
CSH2_k127_2090576_7 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000001694 126.0
CSH2_k127_2090576_8 Tetratricopeptide repeat - - - 0.00000000000000001205 92.0
CSH2_k127_2090576_9 Ribosomal small subunit Rsm22 - - - 0.00000004247 56.0
CSH2_k127_2102672_0 Carbamoyltransferase C-terminus K00612 - - 1.649e-236 745.0
CSH2_k127_2102672_1 1,4-alpha-glucan branching enzyme K00700,K01236 - 2.4.1.18,3.2.1.141 0.000000000000935 71.0
CSH2_k127_2102672_2 - - - - 0.0000002722 58.0
CSH2_k127_2102672_3 - - - - 0.00002164 49.0
CSH2_k127_2120346_0 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 476.0
CSH2_k127_2120346_1 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003918 256.0
CSH2_k127_2120346_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000001169 177.0
CSH2_k127_2121534_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 541.0
CSH2_k127_2121534_1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 331.0
CSH2_k127_2121534_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 321.0
CSH2_k127_2121534_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000001827 173.0
CSH2_k127_2121534_4 HIT domain K02503 - - 0.0000000000000000000000000000000000000001644 164.0
CSH2_k127_2121534_5 - - - - 0.00000000000000000000000001073 120.0
CSH2_k127_2121534_6 - - - - 0.0001101 52.0
CSH2_k127_2159880_0 DNA polymerase X family K02347 - - 7.963e-194 620.0
CSH2_k127_2159880_1 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001647 284.0
CSH2_k127_2190189_0 Pyruvate kinase, alpha/beta domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 464.0
CSH2_k127_2190189_1 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000001166 169.0
CSH2_k127_2191588_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 503.0
CSH2_k127_2191588_1 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000001054 175.0
CSH2_k127_2191588_2 - - - - 0.0001427 48.0
CSH2_k127_2191993_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 548.0
CSH2_k127_2191993_1 - - - - 0.000000000000000009541 91.0
CSH2_k127_2201471_0 response regulator receiver K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 361.0
CSH2_k127_2217625_0 Predicted membrane protein (DUF2339) - - - 6.968e-257 826.0
CSH2_k127_2217625_1 Protein of unknown function (DUF3999) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 484.0
CSH2_k127_2226157_0 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000001914 224.0
CSH2_k127_2226157_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000002274 182.0
CSH2_k127_2226157_2 ABC-2 type transporter - - - 0.00000000002712 74.0
CSH2_k127_2226157_3 peptidyl-tyrosine sulfation - - - 0.0002232 52.0
CSH2_k127_2309919_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.674e-208 656.0
CSH2_k127_2309919_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 496.0
CSH2_k127_2309919_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 456.0
CSH2_k127_2309919_3 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 393.0
CSH2_k127_2309919_4 Belongs to the peptidase S8 family - - - 0.00000000000000000000006097 106.0
CSH2_k127_2309919_5 Forkhead associated domain - - - 0.0000000000000005639 85.0
CSH2_k127_2312236_0 PFAM 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000004816 219.0
CSH2_k127_2312236_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000001229 201.0
CSH2_k127_2312236_2 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.000000000000000000000000001596 125.0
CSH2_k127_2312236_3 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.000004232 59.0
CSH2_k127_2312236_4 Domain of unknown function (DUF4202) - - - 0.0001601 48.0
CSH2_k127_2314682_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.671e-207 659.0
CSH2_k127_2314682_1 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000001018 59.0
CSH2_k127_2315390_0 cellulase activity K01179,K13735,K21449 - 3.2.1.4 1.915e-201 652.0
CSH2_k127_2315390_1 Predicted Permease Membrane Region K07085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 567.0
CSH2_k127_2315390_2 hydrolase activity, hydrolyzing O-glycosyl compounds K01176,K01187 - 3.2.1.1,3.2.1.20 0.00000000000000000000000000000000000000000002835 165.0
CSH2_k127_2315390_3 Protein of unknown function (DUF1800) - - - 0.000002095 56.0
CSH2_k127_231762_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 357.0
CSH2_k127_231762_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002325 283.0
CSH2_k127_231762_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000006807 98.0
CSH2_k127_231762_11 rRNA binding K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000001428 59.0
CSH2_k127_231762_12 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000005262 59.0
CSH2_k127_231762_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000007869 230.0
CSH2_k127_231762_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000005802 195.0
CSH2_k127_231762_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000005919 169.0
CSH2_k127_231762_5 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000001735 130.0
CSH2_k127_231762_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000003021 130.0
CSH2_k127_231762_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000003211 112.0
CSH2_k127_231762_8 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000008409 112.0
CSH2_k127_231762_9 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000227 104.0
CSH2_k127_2326327_0 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 415.0
CSH2_k127_2326327_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 366.0
CSH2_k127_2326327_2 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 352.0
CSH2_k127_2326327_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000009788 182.0
CSH2_k127_2326327_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000003886 96.0
CSH2_k127_2344725_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 360.0
CSH2_k127_2344725_1 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01676,K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000001418 246.0
CSH2_k127_2344725_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000001513 64.0
CSH2_k127_2352045_0 UvrD-like helicase C-terminal domain K03656,K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 516.0
CSH2_k127_2352045_1 Thiazole biosynthesis protein ThiG K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 413.0
CSH2_k127_2352045_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 317.0
CSH2_k127_2352045_3 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003824 278.0
CSH2_k127_2352045_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003867 277.0
CSH2_k127_2352045_5 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000005656 269.0
CSH2_k127_2352045_6 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005433 271.0
CSH2_k127_2352045_7 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000001731 207.0
CSH2_k127_2352045_8 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000006429 87.0
CSH2_k127_2352045_9 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.00000004834 61.0
CSH2_k127_2352047_0 PFAM magnesium chelatase ChlI subunit K07391 - - 9.623e-196 622.0
CSH2_k127_2352047_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005706 281.0
CSH2_k127_2352047_2 - - - - 0.000000000000000000000000000000008485 134.0
CSH2_k127_2367162_0 CbiX - - - 0.00000000000000000000000000000000000000000000000000000000005822 218.0
CSH2_k127_2367162_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000005111 206.0
CSH2_k127_2367162_2 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000003609 194.0
CSH2_k127_2367162_3 Planctomycete cytochrome C - - - 0.00000000000000000001228 99.0
CSH2_k127_236931_0 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000003107 226.0
CSH2_k127_236931_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000003234 198.0
CSH2_k127_236931_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000122 167.0
CSH2_k127_236931_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00000000000614 72.0
CSH2_k127_2386698_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000001326 89.0
CSH2_k127_2386698_1 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.000000000004151 79.0
CSH2_k127_2390479_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 3.007e-236 746.0
CSH2_k127_2390479_1 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 478.0
CSH2_k127_2390479_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001374 285.0
CSH2_k127_2390479_3 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000000000000000000008463 168.0
CSH2_k127_2435691_0 Catalase K03781 - 1.11.1.6 7.94e-257 798.0
CSH2_k127_2435691_1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000006731 242.0
CSH2_k127_2435691_2 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000001214 180.0
CSH2_k127_2435896_0 Arginosuccinate synthase K01940 - 6.3.4.5 4.148e-227 708.0
CSH2_k127_2454374_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 367.0
CSH2_k127_2454374_1 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 334.0
CSH2_k127_2454374_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 295.0
CSH2_k127_2454374_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000004219 212.0
CSH2_k127_2454374_4 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000000005207 144.0
CSH2_k127_2475356_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 322.0
CSH2_k127_2475356_1 typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000002838 255.0
CSH2_k127_2475356_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000002052 112.0
CSH2_k127_2475356_3 Protein of unknown function (DUF2851) - - - 0.0000000000000000000009963 100.0
CSH2_k127_247874_0 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 351.0
CSH2_k127_2498207_0 6-phosphofructokinase activity K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 569.0
CSH2_k127_2498207_1 Lysine-2,3-aminomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 520.0
CSH2_k127_2498207_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 319.0
CSH2_k127_2517238_0 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 327.0
CSH2_k127_2517238_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000004353 135.0
CSH2_k127_2517238_2 Cysteine-rich secretory protein family - - - 0.0000000000000000000002476 106.0
CSH2_k127_2517238_3 Endonuclease/Exonuclease/phosphatase family K12351 GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005773,GO:0005783,GO:0005886,GO:0006629,GO:0006643,GO:0006665,GO:0006672,GO:0006807,GO:0006950,GO:0006970,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009628,GO:0009651,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0019867,GO:0030148,GO:0030149,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031306,GO:0031307,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032592,GO:0032995,GO:0034641,GO:0042578,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0044087,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0046466,GO:0046467,GO:0046513,GO:0046519,GO:0046521,GO:0050789,GO:0050794,GO:0050896,GO:0052712,GO:0052713,GO:0052714,GO:0065007,GO:0071704,GO:0071944,GO:0097164,GO:0098573,GO:0098588,GO:0098805,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1903338 3.1.4.12 0.00000000228 68.0
CSH2_k127_2517238_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000001468 61.0
CSH2_k127_2519095_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000004753 227.0
CSH2_k127_2519095_1 PFAM helix-turn-helix domain protein - - - 0.0000000002398 64.0
CSH2_k127_2519095_2 domain, Protein - - - 0.00002593 58.0
CSH2_k127_2520987_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 9.033e-203 653.0
CSH2_k127_2520987_1 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 501.0
CSH2_k127_2520987_2 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 338.0
CSH2_k127_2520987_3 Putative ABC exporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 311.0
CSH2_k127_2520987_4 membrane transporter protein K07090 - - 0.00000000000000005183 87.0
CSH2_k127_2520987_5 thiamine diphosphate biosynthetic process K03154 - - 0.00000006821 57.0
CSH2_k127_2521049_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 367.0
CSH2_k127_2521049_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000001231 219.0
CSH2_k127_2521049_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.0000000000000000000000000000000000000000000000002384 197.0
CSH2_k127_2551346_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 435.0
CSH2_k127_2551346_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 343.0
CSH2_k127_2551346_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003931 263.0
CSH2_k127_2551346_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000004948 264.0
CSH2_k127_2551346_4 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000000000001572 181.0
CSH2_k127_2551346_5 competence protein - - - 0.0000000000000000000000000000000000000000000003874 175.0
CSH2_k127_2551346_6 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.0000000000000000003319 89.0
CSH2_k127_2588444_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 323.0
CSH2_k127_2588444_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001056 251.0
CSH2_k127_2588444_2 Histidine kinase response regulator - - - 0.0000000000000000000000000000000000000000000000000000000402 203.0
CSH2_k127_2588444_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000004005 177.0
CSH2_k127_2588444_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000003901 163.0
CSH2_k127_2588444_5 O-Antigen ligase - - - 0.00000000000000000000000000000000000005147 163.0
CSH2_k127_2621084_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 427.0
CSH2_k127_2621084_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000007462 121.0
CSH2_k127_2621084_2 Histidine kinase - - - 0.0000000000000001968 91.0
CSH2_k127_2643530_0 Tricorn protease PDZ domain - - - 0.0 1290.0
CSH2_k127_2643530_1 Peptidase dimerisation domain - - - 0.0000000000000000000000004747 108.0
CSH2_k127_2643530_2 AMMECR1 K06990 - - 0.00000000002643 64.0
CSH2_k127_2647764_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 494.0
CSH2_k127_2647764_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 311.0
CSH2_k127_2647764_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000002509 250.0
CSH2_k127_2647764_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.000000000000000162 81.0
CSH2_k127_2655037_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 441.0
CSH2_k127_2655037_1 iron ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000938 281.0
CSH2_k127_2655037_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000001687 226.0
CSH2_k127_2657923_0 Met-10+ like-protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 503.0
CSH2_k127_2657923_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003258 277.0
CSH2_k127_2657923_2 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005773 225.0
CSH2_k127_2657923_3 Nitroreductase family - - - 0.00000000000000000000000000005081 117.0
CSH2_k127_2657923_4 Pirin K06911 - - 0.00000000000001149 73.0
CSH2_k127_2657923_5 - - - - 0.000000006369 66.0
CSH2_k127_2657923_6 - - - - 0.000001761 53.0
CSH2_k127_2675645_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 9.043e-269 849.0
CSH2_k127_2675645_1 Transposase IS200 like - - - 0.00000004244 61.0
CSH2_k127_2677597_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1120.0
CSH2_k127_2677597_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000557 156.0
CSH2_k127_268895_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.509e-290 907.0
CSH2_k127_268895_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000005062 174.0
CSH2_k127_2709672_0 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 439.0
CSH2_k127_2709672_1 Ferredoxin - - - 0.00000000000000000000000000000000000000000241 163.0
CSH2_k127_2709672_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000002715 111.0
CSH2_k127_2719936_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001069 284.0
CSH2_k127_2719936_1 Glutaredoxin K07390 - - 0.00000000000000000000000000000000000001007 150.0
CSH2_k127_2726982_0 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 584.0
CSH2_k127_2726982_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000007487 90.0
CSH2_k127_2775023_0 amine dehydrogenase activity K01173 - - 3.651e-196 649.0
CSH2_k127_2775023_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008088 374.0
CSH2_k127_2775023_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000001591 209.0
CSH2_k127_2775023_3 alpha amylase, catalytic region - - - 0.000000000000000000000000000000000000000001421 160.0
CSH2_k127_279517_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000227 269.0
CSH2_k127_279517_1 PFAM phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000001516 258.0
CSH2_k127_279517_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000001308 96.0
CSH2_k127_279517_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000006571 56.0
CSH2_k127_280931_0 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 477.0
CSH2_k127_280931_1 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.000000000000000000000000000001643 130.0
CSH2_k127_280931_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000001296 87.0
CSH2_k127_280931_3 YaeQ protein - - - 0.00000003024 65.0
CSH2_k127_2825311_0 FAD binding domain of DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 600.0
CSH2_k127_2825311_1 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 359.0
CSH2_k127_2825311_2 RNA pseudouridylate synthase K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000001013 186.0
CSH2_k127_2825311_3 PFAM TspO MBR family protein K05770 - - 0.0000000000008375 69.0
CSH2_k127_2873707_0 Putative Na+/H+ antiporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 529.0
CSH2_k127_2873707_1 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 322.0
CSH2_k127_2873707_2 Protein of unknown function (DUF520) - - - 0.000000000000000000000000000000000000000004349 162.0
CSH2_k127_2873707_3 PFAM Tetratricopeptide repeat - - - 0.0001136 52.0
CSH2_k127_2877503_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 599.0
CSH2_k127_2877503_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000003836 204.0
CSH2_k127_2877503_2 PFAM Transposase, IS4-like - - - 0.00000000000000000000000000002164 132.0
CSH2_k127_2877503_3 - - - - 0.00000005348 61.0
CSH2_k127_2897862_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 529.0
CSH2_k127_2897862_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001248 279.0
CSH2_k127_2897862_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000001412 124.0
CSH2_k127_2897862_3 RNA polymerase sigma factor K03088 - - 0.00000000000000000000006438 106.0
CSH2_k127_2913210_0 Belongs to the glycosyl hydrolase 57 family K03406,K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 576.0
CSH2_k127_2913210_1 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 480.0
CSH2_k127_2913210_2 Putative ATP-binding cassette - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 380.0
CSH2_k127_2913210_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000002503 226.0
CSH2_k127_2913210_4 Rho termination factor K09942 - - 0.00000000000000000000000002848 119.0
CSH2_k127_2916799_0 Serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 321.0
CSH2_k127_2916799_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000000000001494 244.0
CSH2_k127_2916799_2 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000009652 198.0
CSH2_k127_2916799_3 ACT domain - - - 0.0000000000000000000000000000000000000000000005358 170.0
CSH2_k127_2916799_4 DJ-1/PfpI family K03152 - 3.5.1.124 0.000000000000000000000000000000000000000000001237 173.0
CSH2_k127_2916799_5 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000003689 160.0
CSH2_k127_2916799_7 PFAM restriction modification system DNA specificity domain K01154 - 3.1.21.3 0.00003017 46.0
CSH2_k127_2977899_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 505.0
CSH2_k127_2977899_1 PFAM CBS domain containing protein K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 368.0
CSH2_k127_2977899_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 344.0
CSH2_k127_2977899_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000002535 184.0
CSH2_k127_2977899_4 Transmembrane and TPR repeat-containing protein 1 - - - 0.00000004675 65.0
CSH2_k127_2988094_0 DNA topoisomerase, type IA, central K03169 - 5.99.1.2 1.194e-318 996.0
CSH2_k127_2988094_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 383.0
CSH2_k127_2988094_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000004051 203.0
CSH2_k127_2988094_3 TIGRFAM ATP-dependent DNA helicase, RecQ family K03654 - 3.6.4.12 0.0000000000000000000000000002829 117.0
CSH2_k127_2997851_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000004287 227.0
CSH2_k127_2997851_1 N-terminal domain of galactosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000004676 207.0
CSH2_k127_3028379_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 4.372e-210 666.0
CSH2_k127_3028379_1 RecG wedge domain K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 447.0
CSH2_k127_3028379_2 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 334.0
CSH2_k127_3031945_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07083,K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 427.0
CSH2_k127_3031945_1 Glycogen debranching enzyme - - - 0.00000000000000000000000002175 115.0
CSH2_k127_3033715_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 9.798e-197 625.0
CSH2_k127_3033715_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 475.0
CSH2_k127_3033715_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 359.0
CSH2_k127_3033715_3 WYL domain K13572 - - 0.000000000000000000000000000000000000000000000000000000000000000000004223 246.0
CSH2_k127_3033715_4 TIGRFAM phosphocarrier, HPr family K11189 - - 0.0000000000000000000000000000006122 126.0
CSH2_k127_3033715_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000009533 97.0
CSH2_k127_3033715_6 sigma-54 factor interaction domain-containing protein K07712 - - 0.0000000000001032 72.0
CSH2_k127_3033715_7 ABC transporter K06861 - - 0.00000001408 56.0
CSH2_k127_3033715_8 - - - - 0.000001381 54.0
CSH2_k127_3052759_0 Type I site-specific restriction-modification system, R (Restriction) subunit and related - - - 3.432e-215 686.0
CSH2_k127_3052759_1 DUF167 K09131 - - 0.000000000000000141 83.0
CSH2_k127_3062551_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 492.0
CSH2_k127_3062551_1 biotin synthase activity K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 327.0
CSH2_k127_3062551_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000007044 182.0
CSH2_k127_3062551_3 Pfam C-terminal domain of CHU protein family - - - 0.00000000001573 76.0
CSH2_k127_3062551_4 oxidoreductase activity K02396 - - 0.00000000008708 74.0
CSH2_k127_3062551_5 - - - - 0.0004875 51.0
CSH2_k127_3068541_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000002664 256.0
CSH2_k127_3068541_1 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000001412 98.0
CSH2_k127_3068541_2 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 0.000000000000000000211 92.0
CSH2_k127_308067_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001266 282.0
CSH2_k127_308067_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000001968 169.0
CSH2_k127_308067_2 Forkhead associated domain K03466 - - 0.00001154 57.0
CSH2_k127_308155_0 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 468.0
CSH2_k127_308155_1 SPFH domain / Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 417.0
CSH2_k127_308155_2 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008437 250.0
CSH2_k127_308155_3 Metalloenzyme superfamily - - - 0.000000000000000000000000000000000000000000000000000000004542 219.0
CSH2_k127_308155_4 - - - - 0.000000000000000000000000000000000000000000000001165 180.0
CSH2_k127_308155_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000005256 84.0
CSH2_k127_3086797_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.348e-259 811.0
CSH2_k127_3086797_1 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009132 233.0
CSH2_k127_3093490_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 2.494e-227 713.0
CSH2_k127_3093490_1 PFAM phosphoadenosine phosphosulfate reductase K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 541.0
CSH2_k127_3093490_2 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00381 - 1.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 362.0
CSH2_k127_3093490_3 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 334.0
CSH2_k127_3093490_4 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000123 254.0
CSH2_k127_3101935_0 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000004759 130.0
CSH2_k127_3101935_1 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000001018 113.0
CSH2_k127_3101935_2 membrane - - - 0.000000000000000033 96.0
CSH2_k127_3101935_3 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000168 51.0
CSH2_k127_3103731_0 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 422.0
CSH2_k127_3103731_1 TIGRFAM phosphate ABC transporter, inner membrane subunit PstC K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 394.0
CSH2_k127_3103731_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 362.0
CSH2_k127_3103731_3 ATPase-coupled phosphate ion transmembrane transporter activity K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 361.0
CSH2_k127_3103731_4 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 319.0
CSH2_k127_3103731_5 negative regulation of phosphate transmembrane transport K01104,K02039,K03741 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 1.20.4.1,3.1.3.48 0.0000000000000000000000000000000000000164 159.0
CSH2_k127_3103731_6 long-chain fatty acid transporting porin activity K06076 - - 0.00000001446 60.0
CSH2_k127_3113917_0 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000002332 121.0
CSH2_k127_3113917_1 AsmA-like C-terminal region - - - 0.00000000000003609 87.0
CSH2_k127_3118915_0 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 476.0
CSH2_k127_3118915_1 ATP-binding region, ATPase domain protein domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 400.0
CSH2_k127_3118915_2 Domain of unknown function (DUF2437) - - - 0.000000000000000000000000000000000000000000000000000000000000000003299 237.0
CSH2_k127_3118915_3 metal cluster binding K06940 - - 0.000000000000000000000002697 109.0
CSH2_k127_3138688_0 Histidine biosynthesis protein HisG domain K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 386.0
CSH2_k127_3138688_1 cytochrome c biogenesis protein K09792 - - 0.0000000000000000000000003675 108.0
CSH2_k127_3162943_0 denitrification pathway - - - 0.00000000000000000000000000000008093 134.0
CSH2_k127_3162943_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000007951 117.0
CSH2_k127_3200515_0 domain protein K01637,K20276 - 4.1.3.1 0.00000000000000000000000001002 124.0
CSH2_k127_3200515_1 Alpha-2-Macroglobulin K06894 - - 0.0006485 52.0
CSH2_k127_3204547_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 291.0
CSH2_k127_3204547_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000004114 240.0
CSH2_k127_3204547_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000006295 232.0
CSH2_k127_3204547_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000007276 196.0
CSH2_k127_3204547_4 NUDIX domain - - - 0.000000001858 61.0
CSH2_k127_320946_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.268e-210 671.0
CSH2_k127_320946_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 - 2.4.2.8,6.3.4.19 0.0000000000000105 82.0
CSH2_k127_3251806_0 amino acid-binding ACT domain protein K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 401.0
CSH2_k127_3251806_1 SIS domain K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 348.0
CSH2_k127_3251806_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 287.0
CSH2_k127_3251806_3 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000003484 179.0
CSH2_k127_3251806_4 Segregation and condensation complex subunit ScpB - - - 0.000000000000000000000000000000000000005586 154.0
CSH2_k127_3251806_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves - - - 0.0000000000000000000005945 99.0
CSH2_k127_3260072_0 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 609.0
CSH2_k127_3269507_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000003194 130.0
CSH2_k127_3269507_1 Transcriptional regulator with HTH domain and aminotransferase domain K00375 - - 0.00001322 57.0
CSH2_k127_3269507_2 helix_turn _helix lactose operon repressor K02529 - - 0.00009445 54.0
CSH2_k127_3339507_0 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 338.0
CSH2_k127_3339507_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 304.0
CSH2_k127_3339507_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000001152 198.0
CSH2_k127_3339507_4 PFAM Phosphate-selective porin O K07221 - - 0.000000000000000000000000000000000003287 144.0
CSH2_k127_3339507_5 Uncharacterized small protein (DUF2292) - - - 0.000000001946 61.0
CSH2_k127_337349_0 COG0604 NADPH quinone reductase and related Zn-dependent K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 379.0
CSH2_k127_337349_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000001621 257.0
CSH2_k127_337349_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000006933 148.0
CSH2_k127_337349_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000003394 96.0
CSH2_k127_337349_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000004445 96.0
CSH2_k127_339763_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007131 295.0
CSH2_k127_339763_1 endoribonuclease L-PSP K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000002389 162.0
CSH2_k127_339763_2 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000001299 151.0
CSH2_k127_339763_3 PFAM FeoA family protein K04758 - - 0.0000000000005183 75.0
CSH2_k127_339763_4 phosphorelay signal transduction system - - - 0.000000000005411 72.0
CSH2_k127_339763_5 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000003303 64.0
CSH2_k127_339763_6 FeoA domain - - - 0.000005633 53.0
CSH2_k127_3421258_0 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 487.0
CSH2_k127_3421258_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 451.0
CSH2_k127_3421258_10 riboflavin synthase, alpha K00793,K02858,K14652 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9,3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000004291 202.0
CSH2_k127_3421258_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000005938 177.0
CSH2_k127_3421258_12 Protein of unknown function (DUF3450) - - - 0.000000000000000000000000000000000000007994 154.0
CSH2_k127_3421258_13 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000001372 146.0
CSH2_k127_3421258_14 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000003432 144.0
CSH2_k127_3421258_15 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000007745 132.0
CSH2_k127_3421258_16 Protein of unknown function (DUF2723) - - - 0.00000000000000004549 97.0
CSH2_k127_3421258_17 phosphorelay signal transduction system - - - 0.000000000008141 72.0
CSH2_k127_3421258_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 432.0
CSH2_k127_3421258_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 344.0
CSH2_k127_3421258_4 bacteriocin transport K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002465 293.0
CSH2_k127_3421258_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001491 287.0
CSH2_k127_3421258_6 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000001507 270.0
CSH2_k127_3421258_7 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000003265 244.0
CSH2_k127_3421258_8 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000008881 224.0
CSH2_k127_3421258_9 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000002135 214.0
CSH2_k127_3458858_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.609e-240 752.0
CSH2_k127_3458858_1 Cytidylyltransferase K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000003165 229.0
CSH2_k127_3458858_2 CAAX protease self-immunity - - - 0.00000000000000000000001966 110.0
CSH2_k127_3458858_3 - - - - 0.00002928 55.0
CSH2_k127_3505420_0 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000001429 239.0
CSH2_k127_3505420_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000004369 237.0
CSH2_k127_3505420_2 Histidine kinase - - - 0.00000000000000000000000000000000009105 151.0
CSH2_k127_3505420_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0001872 48.0
CSH2_k127_3541193_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.609e-289 901.0
CSH2_k127_3541193_1 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000003859 196.0
CSH2_k127_3541193_2 Domain of Unknown Function (DUF1080) - - - 0.000003549 49.0
CSH2_k127_354625_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01885,K01894 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 379.0
CSH2_k127_354625_1 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000004832 261.0
CSH2_k127_354625_2 Conserved repeat domain - - - 0.00000000000000000000000000000000005322 145.0
CSH2_k127_354625_3 Arsenical pump membrane protein - - - 0.0000000000000000000000000007661 115.0
CSH2_k127_3546460_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 511.0
CSH2_k127_3546460_2 Cytochrome c - - - 0.0000000000000000000929 94.0
CSH2_k127_3546545_0 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 0.0 1060.0
CSH2_k127_3546545_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 8.881e-263 820.0
CSH2_k127_3546545_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 9.267e-199 644.0
CSH2_k127_3546545_3 TIGRFAM cytochrome c oxidase accessory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 516.0
CSH2_k127_3546545_4 PFAM Cytochrome c, class I K00406 - - 0.000000000000000000000000000000000000000003005 163.0
CSH2_k127_3546545_5 Helix-turn-helix - - - 0.000000000000000000000001953 108.0
CSH2_k127_3546545_6 Cytochrome oxidase maturation protein - - - 0.00000006489 60.0
CSH2_k127_3548187_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 421.0
CSH2_k127_3548187_1 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 402.0
CSH2_k127_3548187_2 Zinc-uptake complex component A periplasmic K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000767 253.0
CSH2_k127_3548187_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000004321 226.0
CSH2_k127_3548187_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000001601 100.0
CSH2_k127_3548187_5 Haloacid dehalogenase-like hydrolase - - - 0.0002559 46.0
CSH2_k127_3550201_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 466.0
CSH2_k127_3550201_1 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000004885 134.0
CSH2_k127_3550201_2 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000007767 115.0
CSH2_k127_3550201_3 CobQ/CobB/MinD/ParA nucleotide binding domain K07321 - - 0.0000000000000001228 92.0
CSH2_k127_3550201_4 Dinitrogenase iron-molybdenum cofactor - - - 0.00004554 52.0
CSH2_k127_3550201_5 Protein of unknown function DUF89 K09116 - - 0.0003759 52.0
CSH2_k127_3555234_0 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 411.0
CSH2_k127_3555234_1 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001746 286.0
CSH2_k127_3555234_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000002599 269.0
CSH2_k127_3555234_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000001669 246.0
CSH2_k127_3555234_4 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000003981 193.0
CSH2_k127_3555234_5 Stress responsive A/B Barrel Domain - - - 0.00000000000000000000000000000000000001651 147.0
CSH2_k127_3583059_0 Prokaryotic cytochrome b561 - - - 2.528e-314 977.0
CSH2_k127_3583059_1 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 302.0
CSH2_k127_3583059_2 Formyl transferase, C-terminal domain K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001973 280.0
CSH2_k127_3583059_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000002942 229.0
CSH2_k127_3583059_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000009119 222.0
CSH2_k127_3584758_0 PFAM LysM domain - - - 0.000000002477 67.0
CSH2_k127_3584758_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000007852 57.0
CSH2_k127_358975_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001472 273.0
CSH2_k127_358975_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000009831 74.0
CSH2_k127_358975_2 dienelactone hydrolase - - - 0.00001172 55.0
CSH2_k127_360571_0 FeoA - - - 1.22e-199 632.0
CSH2_k127_360571_1 Ferrous iron transport protein B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 369.0
CSH2_k127_360571_2 iron ion homeostasis K03322,K03709,K04758 - - 0.0000000000000000000000000000000000000000000000000000000000000000000141 246.0
CSH2_k127_360571_3 Ftsk_gamma K03466 - - 0.00000000000000001695 95.0
CSH2_k127_3618938_0 glycoside hydrolase family 13 K00749 GO:0000003,GO:0000271,GO:0003006,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005575,GO:0005618,GO:0005619,GO:0005623,GO:0005628,GO:0005975,GO:0005976,GO:0006073,GO:0007049,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009272,GO:0009277,GO:0009653,GO:0009987,GO:0010383,GO:0010927,GO:0016020,GO:0016043,GO:0016051,GO:0016160,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016798,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022607,GO:0030154,GO:0030312,GO:0030435,GO:0030437,GO:0030476,GO:0030978,GO:0030979,GO:0031160,GO:0031505,GO:0032502,GO:0032505,GO:0032989,GO:0033692,GO:0034293,GO:0034637,GO:0034645,GO:0042244,GO:0042546,GO:0042763,GO:0042764,GO:0043170,GO:0043934,GO:0043935,GO:0044036,GO:0044038,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0044703,GO:0045229,GO:0047657,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0070589,GO:0070590,GO:0070591,GO:0070592,GO:0070595,GO:0070596,GO:0070597,GO:0070598,GO:0070599,GO:0070600,GO:0070726,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071852,GO:0071940,GO:0071944,GO:1901576,GO:1903046 2.4.1.183 0.0000000000000000000000000000000000000000000000000000004616 219.0
CSH2_k127_3627531_0 General secretory system II protein E domain protein K02454,K02652 - - 2.399e-201 642.0
CSH2_k127_3627531_1 twitching motility protein K02669 - - 0.000000000001252 69.0
CSH2_k127_3627978_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism - - - 3.038e-227 725.0
CSH2_k127_3627978_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000007235 93.0
CSH2_k127_3638647_0 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000051 272.0
CSH2_k127_3638647_1 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.000000000000000000000000000000000002522 139.0
CSH2_k127_3638647_2 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000006745 139.0
CSH2_k127_3638647_3 cobalt ABC transporter, permease K02008 - - 0.0000000000000000001709 96.0
CSH2_k127_3638647_4 phosphoribosylamine-glycine ligase activity K01945,K01955 - 6.3.4.13,6.3.5.5 0.000001164 51.0
CSH2_k127_3638647_5 PDGLE domain K02009 - - 0.000005658 49.0
CSH2_k127_3643706_0 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 426.0
CSH2_k127_3643706_1 DRTGG domain K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 409.0
CSH2_k127_3643706_2 PFAM phosphate acetyl butaryl transferase K00625,K13788 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 362.0
CSH2_k127_3643706_3 Conserved repeat domain - - - 0.000000000000000000000000000000000000001833 167.0
CSH2_k127_3643706_4 C4-type zinc ribbon domain K07164 - - 0.00001271 50.0
CSH2_k127_3698167_0 Subtilase family - - - 0.00000000000000000000000000000000000000006401 174.0
CSH2_k127_3709502_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 317.0
CSH2_k127_3711498_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.151e-206 661.0
CSH2_k127_3711498_1 protein involved in exopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 577.0
CSH2_k127_3711498_2 Semialdehyde dehydrogenase, NAD binding domain K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 415.0
CSH2_k127_3711498_3 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007352 274.0
CSH2_k127_3711498_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000001192 189.0
CSH2_k127_3711498_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000879 151.0
CSH2_k127_3711498_6 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000002268 117.0
CSH2_k127_3711498_7 amine dehydrogenase activity K20276 - - 0.000009238 59.0
CSH2_k127_3721172_0 - - - - 0.000000008758 70.0
CSH2_k127_3727338_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 1.535e-287 894.0
CSH2_k127_3727338_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 295.0
CSH2_k127_373552_0 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 557.0
CSH2_k127_373552_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 500.0
CSH2_k127_373552_2 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 399.0
CSH2_k127_373552_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 311.0
CSH2_k127_373552_4 SUF system FeS assembly protein K04488 - - 0.00000000000000000000000000000000000000000000002892 176.0
CSH2_k127_373552_5 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000001463 161.0
CSH2_k127_373552_6 Glycosyl transferase WecB/TagA/CpsF family - - - 0.0000000000000000000000000000000004693 145.0
CSH2_k127_3761361_0 L-arabinokinase-like K12446 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005911,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009506,GO:0009702,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0030054,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0055044,GO:0071704 2.7.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 302.0
CSH2_k127_3761361_1 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 291.0
CSH2_k127_3761361_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01880 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000008789 243.0
CSH2_k127_3761361_3 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000002514 185.0
CSH2_k127_3761361_4 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000115 147.0
CSH2_k127_3761361_5 membrane - - - 0.0000000000000000000000000002468 128.0
CSH2_k127_3761361_6 Sigma-70, region 4 - - - 0.00000000009036 62.0
CSH2_k127_3761361_7 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000002417 68.0
CSH2_k127_3763619_0 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000008555 126.0
CSH2_k127_3763619_1 Type IV pilus assembly protein PilM K02662 - - 0.0000000001581 73.0
CSH2_k127_3773098_0 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000003835 105.0
CSH2_k127_3811220_0 lipolytic protein G-D-S-L family K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 384.0
CSH2_k127_3811220_1 extracellular matrix structural constituent - - - 0.00000000143 71.0
CSH2_k127_3851011_0 Phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000001528 223.0
CSH2_k127_3851011_1 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000002019 157.0
CSH2_k127_3851011_3 general secretion pathway protein K02456,K02679 - - 0.0000007547 59.0
CSH2_k127_3863515_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.792e-289 895.0
CSH2_k127_3863515_1 IMP dehydrogenase GMP reductase K00088 - 1.1.1.205 3.083e-211 664.0
CSH2_k127_3863515_2 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 519.0
CSH2_k127_3863515_3 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 506.0
CSH2_k127_3863515_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 395.0
CSH2_k127_3863515_5 Cytochrome c K12263 - - 0.00000000000000000000000000000000000000000000000001806 192.0
CSH2_k127_388089_0 CBS domain containing protein K15986 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 522.0
CSH2_k127_388089_1 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000001342 194.0
CSH2_k127_3911618_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 404.0
CSH2_k127_3911618_1 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000001444 254.0
CSH2_k127_3911618_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000001009 157.0
CSH2_k127_3911618_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000009173 154.0
CSH2_k127_3911618_4 regulation of translation K03530,K04764 - - 0.0000000000000000000000000000002404 131.0
CSH2_k127_3911618_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000002719 108.0
CSH2_k127_3911618_6 PurA ssDNA and RNA-binding protein - - - 0.00000000000000001785 85.0
CSH2_k127_3922902_0 phosphoribosylamine-glycine ligase activity K01945,K01955 - 6.3.4.13,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 472.0
CSH2_k127_3922902_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 410.0
CSH2_k127_3922902_2 PFAM Arginine-tRNA-protein transferase, C terminus K21420 - 2.3.2.29 0.00000000000000000000000000000001498 137.0
CSH2_k127_3922902_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000415 70.0
CSH2_k127_3948222_0 Glutamine synthetase type III K01915 - 6.3.1.2 2.394e-299 932.0
CSH2_k127_3948222_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000001175 221.0
CSH2_k127_3995423_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 283.0
CSH2_k127_3995423_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000005167 200.0
CSH2_k127_3995423_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000001358 178.0
CSH2_k127_4027653_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 505.0
CSH2_k127_4027653_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 296.0
CSH2_k127_4027653_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 GO:0000502,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017171,GO:0019538,GO:0019899,GO:0030163,GO:0031597,GO:0032991,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051117,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.21.92 0.00000000000000000000000000001736 119.0
CSH2_k127_4027653_3 transcriptional regulator - - - 0.0000005346 59.0
CSH2_k127_4034705_0 OPT oligopeptide transporter protein - - - 1.495e-224 712.0
CSH2_k127_4034705_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 516.0
CSH2_k127_4034705_2 Aldo/keto reductase family K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000093 432.0
CSH2_k127_4034705_3 Competence-damaged protein K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 349.0
CSH2_k127_4034705_4 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 295.0
CSH2_k127_4034705_5 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000000000000000000000000000554 137.0
CSH2_k127_4034705_6 - - - - 0.000000000000002621 88.0
CSH2_k127_403883_0 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 336.0
CSH2_k127_403883_1 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000000001991 164.0
CSH2_k127_403883_2 PFAM Fibronectin type III domain - - - 0.00000000000008796 77.0
CSH2_k127_403883_3 Competence protein ComEC K02238 - - 0.00000000000013 84.0
CSH2_k127_403883_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00796,K00950,K01633,K13940 - 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 0.00000000002995 70.0
CSH2_k127_4042620_0 AAA ATPase central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 546.0
CSH2_k127_4042620_1 Endoribonuclease that initiates mRNA decay K18682 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 444.0
CSH2_k127_4042620_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000005074 111.0
CSH2_k127_4042620_3 nuclear chromosome segregation - - - 0.0000000002147 66.0
CSH2_k127_4070380_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 445.0
CSH2_k127_4070380_1 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 350.0
CSH2_k127_4070380_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003793 276.0
CSH2_k127_4070380_3 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000003457 245.0
CSH2_k127_4070380_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000007576 165.0
CSH2_k127_4070380_5 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000435 120.0
CSH2_k127_4070380_6 threonine efflux protein - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015174,GO:0015181,GO:0015318,GO:0015711,GO:0015802,GO:0015807,GO:0015809,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902023,GO:1903825,GO:1903826,GO:1905039,GO:1990822 - 0.0000000000000004759 87.0
CSH2_k127_4113811_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 598.0
CSH2_k127_4113811_1 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 502.0
CSH2_k127_4113811_2 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 400.0
CSH2_k127_4113811_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 362.0
CSH2_k127_4113811_4 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000004077 216.0
CSH2_k127_4168326_0 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000007638 184.0
CSH2_k127_4185604_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 581.0
CSH2_k127_4185604_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 414.0
CSH2_k127_4185604_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007869 276.0
CSH2_k127_4185604_3 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000007982 254.0
CSH2_k127_4185604_4 Protein of unknown function (DUF1648) - - - 0.0007936 44.0
CSH2_k127_4205799_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 9.774e-196 622.0
CSH2_k127_4205799_1 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 316.0
CSH2_k127_4205799_2 CHAD domain - - - 0.000000000000271 81.0
CSH2_k127_4228633_0 Histidine kinase K07637,K07638,K07717 - 2.7.13.3 0.0000000000000000000000000000000000001984 149.0
CSH2_k127_4228633_1 S-layer homology domain - - - 0.000000000000000282 93.0
CSH2_k127_4278374_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007528 563.0
CSH2_k127_4278374_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000036 297.0
CSH2_k127_4278374_2 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000000000000000136 173.0
CSH2_k127_432609_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1142.0
CSH2_k127_432609_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002676 256.0
CSH2_k127_432609_2 - - - - 0.000000000000000000000000000000000004593 141.0
CSH2_k127_4349025_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 574.0
CSH2_k127_4349025_1 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 548.0
CSH2_k127_4349025_2 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 475.0
CSH2_k127_4349025_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 416.0
CSH2_k127_4349025_4 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.00000003815 64.0
CSH2_k127_4394267_0 Major facilitator Superfamily K16210 - - 0.00000000000000000000000000000000000000000000000000001105 200.0
CSH2_k127_4394267_1 PFAM PKD domain containing protein - - - 0.00000000000004519 85.0
CSH2_k127_4470470_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 307.0
CSH2_k127_4470470_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000002201 230.0
CSH2_k127_4470470_2 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.0000000000000000000000005858 114.0
CSH2_k127_4470470_3 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000001593 109.0
CSH2_k127_449857_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000007543 231.0
CSH2_k127_449857_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000006385 217.0
CSH2_k127_449857_2 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.000000000000000000000000000000000004209 141.0
CSH2_k127_4502811_0 Uncharacterized protein family (UPF0051) K09014 - - 3.141e-259 806.0
CSH2_k127_4502811_1 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 379.0
CSH2_k127_4502811_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000009268 148.0
CSH2_k127_4502811_3 Belongs to the Fur family K09825 - - 0.0000000000000000000000000000000005986 138.0
CSH2_k127_4502811_4 permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000005634 128.0
CSH2_k127_4504082_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000002361 211.0
CSH2_k127_4504082_1 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000719 140.0
CSH2_k127_4504082_2 Glucose / Sorbosone dehydrogenase - - - 0.0000006031 63.0
CSH2_k127_4507031_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 4.339e-303 947.0
CSH2_k127_4507031_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 295.0
CSH2_k127_4522636_0 HMGL-like K01666 - 4.1.3.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 451.0
CSH2_k127_4522636_1 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 377.0
CSH2_k127_4522636_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000003864 195.0
CSH2_k127_4556808_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 2.763e-211 675.0
CSH2_k127_460891_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000008038 185.0
CSH2_k127_460891_1 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.00000000000000000000000000000000004886 142.0
CSH2_k127_460891_2 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000002782 135.0
CSH2_k127_460891_3 L-rhamnose-proton symport protein (RhaT) K02856 - - 0.000004938 54.0
CSH2_k127_4619793_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.251e-256 797.0
CSH2_k127_4619793_1 Dihydrofolate reductase K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000005447 184.0
CSH2_k127_4619793_2 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000211 93.0
CSH2_k127_4653001_0 SbmA/BacA-like family K02471 - - 0.00000000000000000000000000000000000000000000184 172.0
CSH2_k127_4653001_1 hyperosmotic response - - - 0.00000000000000000000008853 108.0
CSH2_k127_4653001_2 - - - - 0.000000000000000000006657 99.0
CSH2_k127_4667901_0 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 536.0
CSH2_k127_4667901_1 - K07283 - - 0.00000000000004254 78.0
CSH2_k127_46844_0 mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 368.0
CSH2_k127_46844_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 357.0
CSH2_k127_46844_2 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000001893 204.0
CSH2_k127_46844_3 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000985 186.0
CSH2_k127_46844_4 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000001664 148.0
CSH2_k127_46844_5 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000004969 123.0
CSH2_k127_46844_6 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000149 110.0
CSH2_k127_46844_7 - K07283 - - 0.000000000000000006397 93.0
CSH2_k127_46844_8 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0001206 54.0
CSH2_k127_4702756_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 462.0
CSH2_k127_4702756_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 293.0
CSH2_k127_4702756_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000001417 205.0
CSH2_k127_4702756_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000001273 207.0
CSH2_k127_4702756_4 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000007866 164.0
CSH2_k127_4702756_5 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000003892 124.0
CSH2_k127_4702756_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000002848 79.0
CSH2_k127_4702756_7 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001357 68.0
CSH2_k127_4702756_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000003031 60.0
CSH2_k127_4702756_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000001731 55.0
CSH2_k127_4751308_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 550.0
CSH2_k127_4751308_1 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000005761 162.0
CSH2_k127_4751308_2 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000001963 76.0
CSH2_k127_4770783_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 0.0 1034.0
CSH2_k127_4770783_1 PFAM Bacterial regulatory proteins, lacI family K02529 - - 0.0000000000000000000000000000000000000000000000000000000005227 214.0
CSH2_k127_4770783_2 - - - - 0.000000002282 66.0
CSH2_k127_4787110_0 Crp Fnr family K21563 - - 0.000000000000000000000000000000000000000000000000000000002673 218.0
CSH2_k127_4787110_1 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000000002826 129.0
CSH2_k127_4787110_2 Protein of unknown function DUF72 - - - 0.00000000000004535 75.0
CSH2_k127_4787110_3 Belongs to the heme-copper respiratory oxidase family - - - 0.000000003682 67.0
CSH2_k127_478833_0 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 377.0
CSH2_k127_478833_1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 301.0
CSH2_k127_478833_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000004521 204.0
CSH2_k127_4794329_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 435.0
CSH2_k127_4794329_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 410.0
CSH2_k127_4794329_2 DNA polymerase K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000002188 225.0
CSH2_k127_4816324_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 1.999e-235 738.0
CSH2_k127_4816324_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.706e-206 651.0
CSH2_k127_4816324_10 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000015 106.0
CSH2_k127_4816324_11 protein conserved in bacteria K09793 - - 0.000000000000000000000007123 108.0
CSH2_k127_4816324_12 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000003463 81.0
CSH2_k127_4816324_13 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000003307 55.0
CSH2_k127_4816324_14 TPR repeat - - - 0.0002336 53.0
CSH2_k127_4816324_2 Nitronate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 625.0
CSH2_k127_4816324_3 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 456.0
CSH2_k127_4816324_4 PFAM Patatin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 408.0
CSH2_k127_4816324_5 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 399.0
CSH2_k127_4816324_6 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 304.0
CSH2_k127_4816324_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 289.0
CSH2_k127_4816324_8 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000005452 227.0
CSH2_k127_4822505_0 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 339.0
CSH2_k127_4862630_0 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 302.0
CSH2_k127_4862630_1 Thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000346 186.0
CSH2_k127_4862630_2 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000001323 168.0
CSH2_k127_4882602_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000002732 241.0
CSH2_k127_4882602_1 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 0.000000000000000000000000000000000000000000000000000000008862 213.0
CSH2_k127_4899179_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 494.0
CSH2_k127_4899179_1 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 319.0
CSH2_k127_4899179_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000001248 192.0
CSH2_k127_4899179_3 Domain of unknown function (DUF4404) - - - 0.0000000000000000000000000205 112.0
CSH2_k127_4910856_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833,K19563 - 2.6.1.105,2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000005086 247.0
CSH2_k127_4910856_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03471 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000002344 240.0
CSH2_k127_4910856_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000001901 230.0
CSH2_k127_4910856_3 EVE domain - - - 0.000000000000000000000000000000000000000000002635 169.0
CSH2_k127_4910856_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000000006128 151.0
CSH2_k127_4910856_5 EamA-like transporter family - - - 0.0000000004828 71.0
CSH2_k127_4923592_0 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 1.471e-198 630.0
CSH2_k127_4923592_1 Aldehyde dehydrogenase family K04021 - - 9.341e-195 619.0
CSH2_k127_4923592_10 BMC - - - 0.00000000000000000000000000000000002421 136.0
CSH2_k127_4923592_11 BMC K04027 - - 0.0000000000000000000000000000000002903 133.0
CSH2_k127_4923592_12 BMC - - - 0.0000000000000000000000000000003361 124.0
CSH2_k127_4923592_13 PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000004227 84.0
CSH2_k127_4923592_2 Domain of unknown function (DUF3390) K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 587.0
CSH2_k127_4923592_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 502.0
CSH2_k127_4923592_4 Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 340.0
CSH2_k127_4923592_5 PFAM Major facilitator superfamily K02429 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 337.0
CSH2_k127_4923592_6 Fe-S oxidoreductase K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000017 266.0
CSH2_k127_4923592_7 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000004781 213.0
CSH2_k127_4923592_8 DeoR C terminal sensor domain - - - 0.00000000000000000000000000000000000000000000000002173 191.0
CSH2_k127_4923592_9 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.000000000000000000000000000000000001592 143.0
CSH2_k127_4953769_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.586e-217 683.0
CSH2_k127_4953769_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 462.0
CSH2_k127_4953769_2 Heavy-metal-associated domain K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 462.0
CSH2_k127_4953769_3 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000003602 277.0
CSH2_k127_4953769_4 Belongs to the P(II) protein family - - - 0.0000000000000000000000000000000000000000000000000002033 186.0
CSH2_k127_4953769_5 AAA domain K01935 - 6.3.3.3 0.00000000000000000000001007 108.0
CSH2_k127_495989_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 400.0
CSH2_k127_495989_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000007921 233.0
CSH2_k127_495989_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000002492 214.0
CSH2_k127_495989_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000002228 205.0
CSH2_k127_495989_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000001626 154.0
CSH2_k127_4968902_0 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000000000000000000000000000000000002881 244.0
CSH2_k127_4968902_1 Acyl-protein synthetase, LuxE - - - 0.0000000000000000000000000000000000000000000000000000006043 208.0
CSH2_k127_4968902_2 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000001017 185.0
CSH2_k127_4968902_3 Thioredoxin K03671 - - 0.000000000000000000000000000000000006651 139.0
CSH2_k127_4971067_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 1.773e-195 619.0
CSH2_k127_4971067_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 572.0
CSH2_k127_4971067_2 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 479.0
CSH2_k127_4971067_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 453.0
CSH2_k127_4971067_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004953 269.0
CSH2_k127_4971067_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000005365 223.0
CSH2_k127_4971067_6 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000009217 184.0
CSH2_k127_4971067_7 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000001096 101.0
CSH2_k127_5001064_0 PFAM peptidase M16 domain protein K07263 - - 3.707e-218 709.0
CSH2_k127_5001064_1 PFAM S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000001717 220.0
CSH2_k127_5002231_0 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001131 232.0
CSH2_k127_5002231_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000575 143.0
CSH2_k127_5002231_2 methyltransferase - - - 0.0000000000001503 82.0
CSH2_k127_5002231_3 Alpha-1,3-glucan synthase K00749 GO:0000003,GO:0000271,GO:0003006,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005575,GO:0005618,GO:0005619,GO:0005623,GO:0005628,GO:0005975,GO:0005976,GO:0006073,GO:0007049,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009272,GO:0009277,GO:0009653,GO:0009987,GO:0010383,GO:0010927,GO:0016020,GO:0016043,GO:0016051,GO:0016160,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016798,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022607,GO:0030154,GO:0030312,GO:0030435,GO:0030437,GO:0030476,GO:0030978,GO:0030979,GO:0031160,GO:0031505,GO:0032502,GO:0032505,GO:0032989,GO:0033692,GO:0034293,GO:0034637,GO:0034645,GO:0042244,GO:0042546,GO:0042763,GO:0042764,GO:0043170,GO:0043934,GO:0043935,GO:0044036,GO:0044038,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0044703,GO:0045229,GO:0047657,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0070589,GO:0070590,GO:0070591,GO:0070592,GO:0070595,GO:0070596,GO:0070597,GO:0070598,GO:0070599,GO:0070600,GO:0070726,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071852,GO:0071940,GO:0071944,GO:1901576,GO:1903046 2.4.1.183 0.000000000008435 70.0
CSH2_k127_5032325_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 401.0
CSH2_k127_5032325_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 387.0
CSH2_k127_5032325_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000003189 130.0
CSH2_k127_5032325_3 mannose-6-phosphate isomerase, class I K01809 - 5.3.1.8 0.00000000000000000001582 93.0
CSH2_k127_5050617_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 344.0
CSH2_k127_5050617_1 Rhomboid family - - - 0.0000000000000000000000008819 118.0
CSH2_k127_5050617_2 domain, Protein - - - 0.0000007479 63.0
CSH2_k127_5055955_0 Phospholipase_D-nuclease N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 550.0
CSH2_k127_5055955_1 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000003397 175.0
CSH2_k127_5055955_2 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000005902 127.0
CSH2_k127_5055955_3 TIGRFAM regulatory protein, FmdB - - - 0.000000003175 61.0
CSH2_k127_5066864_0 Ferrochelatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 388.0
CSH2_k127_5066864_1 phosphorelay signal transduction system - - - 0.000000000000000000001364 108.0
CSH2_k127_5066864_2 PBS lyase HEAT-like repeat - - - 0.0000000000000163 84.0
CSH2_k127_5080599_0 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 305.0
CSH2_k127_5080599_1 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000002215 234.0
CSH2_k127_5080599_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001466 234.0
CSH2_k127_5086029_0 Belongs to the citrate synthase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 599.0
CSH2_k127_5086029_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 423.0
CSH2_k127_5086029_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 341.0
CSH2_k127_5086029_3 Cobalamin adenosyltransferase - - - 0.000000000000000000000000000000000000000000000000005 191.0
CSH2_k127_5086029_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000001135 122.0
CSH2_k127_5086029_5 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000003072 130.0
CSH2_k127_5086029_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000004475 73.0
CSH2_k127_5119409_0 Thermophilic metalloprotease (M29) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000732 482.0
CSH2_k127_5119409_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 314.0
CSH2_k127_5119409_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000001545 139.0
CSH2_k127_5122376_0 Fibronectin type 3 domain - - - 0.0000000001052 75.0
CSH2_k127_5140455_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 385.0
CSH2_k127_5140455_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 384.0
CSH2_k127_5140455_2 - - - - 0.0000000000000000000000002526 110.0
CSH2_k127_5160259_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01818 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008736,GO:0008790,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046372,GO:0071704,GO:1901575 5.3.1.25,5.3.1.3 2.375e-290 902.0
CSH2_k127_5160259_1 PFAM Major facilitator superfamily K02429 - - 0.00000000000000000000000000000000000000000000000000000000003955 209.0
CSH2_k127_5160259_2 RbsD / FucU transport protein family K02431 - 5.1.3.29 0.000000000000000000000000000000000000000000000000000000003271 202.0
CSH2_k127_5160259_3 transcriptional regulator (AraC family) - - - 0.000000000000000000000000001472 121.0
CSH2_k127_5173578_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 285.0
CSH2_k127_5173578_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000003401 180.0
CSH2_k127_5173578_2 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000245 82.0
CSH2_k127_5173578_3 Acetyltransferase (GNAT) family - - - 0.00062 50.0
CSH2_k127_5194597_0 Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 402.0
CSH2_k127_5194597_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 316.0
CSH2_k127_5194597_2 PAP2 superfamily - - - 0.0000000000000000000000000000000000000005339 160.0
CSH2_k127_5213572_0 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 426.0
CSH2_k127_5213572_1 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 408.0
CSH2_k127_5213572_2 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001119 281.0
CSH2_k127_5213572_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000005119 233.0
CSH2_k127_5215581_0 PFAM Glucuronate isomerase K01812 - 5.3.1.12 1.917e-231 724.0
CSH2_k127_5215581_1 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 575.0
CSH2_k127_5215581_2 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 471.0
CSH2_k127_5215581_3 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000005514 265.0
CSH2_k127_5215581_4 PFAM major facilitator superfamily MFS_1 K08191 - - 0.0000002889 54.0
CSH2_k127_5218285_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 548.0
CSH2_k127_5218285_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 479.0
CSH2_k127_5218285_2 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 411.0
CSH2_k127_5218285_3 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 375.0
CSH2_k127_5218285_4 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 307.0
CSH2_k127_5218285_5 Hit family K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000004725 179.0
CSH2_k127_5218285_6 GGDEF domain - - - 0.000000000000000000000000000019 132.0
CSH2_k127_5218285_7 Diguanylate cyclase, GGDEF domain - - - 0.00000000000004067 84.0
CSH2_k127_5222364_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000001057 180.0
CSH2_k127_5222364_1 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000001885 97.0
CSH2_k127_5222364_2 general secretion pathway protein - - - 0.000000000000000007317 92.0
CSH2_k127_5226085_0 Type III restriction protein res subunit K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 494.0
CSH2_k127_5226085_1 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 310.0
CSH2_k127_5226085_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 290.0
CSH2_k127_5226085_3 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004302 287.0
CSH2_k127_5226085_4 Flavoprotein K01598 - 4.1.1.36 0.000000000000000000000000000000000000000000000000000000000000004281 222.0
CSH2_k127_5226085_5 Type III restriction protein res subunit K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000003283 207.0
CSH2_k127_5226085_6 Guanylate kinase K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000001602 189.0
CSH2_k127_5226085_7 Histidine kinase K07709 - 2.7.13.3 0.00000000000000000000000000000000005407 150.0
CSH2_k127_5226085_8 DNA-sulfur modification-associated - - - 0.0000000009614 68.0
CSH2_k127_5231517_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 587.0
CSH2_k127_5231517_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 536.0
CSH2_k127_5231517_2 Nucleoside recognition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 421.0
CSH2_k127_5231517_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000003443 223.0
CSH2_k127_5231517_4 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000008814 143.0
CSH2_k127_5265905_0 glutamate synthase K00284 - 1.4.7.1 5.019e-194 612.0
CSH2_k127_5265905_1 TIGRFAM glutamate synthases, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 487.0
CSH2_k127_5275107_0 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 436.0
CSH2_k127_5301418_0 RnfC Barrel sandwich hybrid domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 603.0
CSH2_k127_5301418_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 605.0
CSH2_k127_5301418_2 Chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 406.0
CSH2_k127_5301418_3 ethanolamine catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008279 246.0
CSH2_k127_5301418_4 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000002459 93.0
CSH2_k127_5301418_5 Forkhead associated domain - - - 0.000001749 55.0
CSH2_k127_5305355_0 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000004258 213.0
CSH2_k127_5305355_1 DNA-templated transcription, initiation - - - 0.00000000000002529 82.0
CSH2_k127_5305355_2 PFAM PKD domain containing protein - - - 0.0001298 51.0
CSH2_k127_5352518_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 410.0
CSH2_k127_5352518_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000055 237.0
CSH2_k127_5352518_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000107 207.0
CSH2_k127_5352518_3 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000001128 153.0
CSH2_k127_5352518_4 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000002861 148.0
CSH2_k127_5352518_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000001572 126.0
CSH2_k127_5352518_6 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000004162 115.0
CSH2_k127_5352518_7 - - - - 0.0000000000000000001482 91.0
CSH2_k127_5352762_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 374.0
CSH2_k127_5352762_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000001098 156.0
CSH2_k127_5352762_2 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000001755 93.0
CSH2_k127_5352762_3 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00005115 53.0
CSH2_k127_5354404_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001073 265.0
CSH2_k127_5354404_1 Beta-lactamase superfamily domain K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000002096 236.0
CSH2_k127_5354404_2 SpoU rRNA Methylase - - - 0.00000000000000000000000000006386 123.0
CSH2_k127_5354404_3 Thioesterase superfamily - - - 0.0000000000000000000004066 106.0
CSH2_k127_5354404_4 Bacterial regulatory protein, Fis family - - - 0.000000000000000002631 93.0
CSH2_k127_5374472_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 9.377e-214 695.0
CSH2_k127_5380811_0 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 342.0
CSH2_k127_5380811_1 cellulose binding - - - 0.00000000000000000000000000000000000000000292 172.0
CSH2_k127_5437092_0 Cytochrome c554 and c-prime - - - 6.585e-219 695.0
CSH2_k127_5437092_1 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 550.0
CSH2_k127_5445618_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 294.0
CSH2_k127_5448569_0 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 1.265e-225 717.0
CSH2_k127_5448569_1 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 387.0
CSH2_k127_5448569_3 integral membrane protein - - - 0.0000117 50.0
CSH2_k127_5500725_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 483.0
CSH2_k127_5500725_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002994 287.0
CSH2_k127_5500725_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000004846 151.0
CSH2_k127_5500725_3 AMMECR1 - - - 0.0000000000000000000001437 103.0
CSH2_k127_5501890_0 Bacterial type II and III secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003462 258.0
CSH2_k127_550760_0 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000003681 194.0
CSH2_k127_550760_1 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000467 154.0
CSH2_k127_550760_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000001199 152.0
CSH2_k127_550760_3 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000157 56.0
CSH2_k127_550760_4 - - - - 0.0001427 48.0
CSH2_k127_5510360_0 DEAD DEAH box helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 438.0
CSH2_k127_5545614_0 Flavin containing amine oxidoreductase - - - 1.257e-257 800.0
CSH2_k127_5545614_1 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 400.0
CSH2_k127_5545614_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0000000000000000000000000001652 128.0
CSH2_k127_5545614_3 esterase - - - 0.0000000000000000000000001184 112.0
CSH2_k127_5571455_0 guanyl-nucleotide exchange factor activity K01183,K20276 GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000009294 252.0
CSH2_k127_5581493_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 301.0
CSH2_k127_5581493_1 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004128 276.0
CSH2_k127_5583091_0 Domain of unknown function (DUF4070) - - - 2.575e-243 759.0
CSH2_k127_5583091_1 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 366.0
CSH2_k127_5583091_2 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 353.0
CSH2_k127_5583091_3 Nucleoside H+ symporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 329.0
CSH2_k127_5583091_4 SelR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005418 247.0
CSH2_k127_5583091_5 PFAM DNA topoisomerase type IA zn finger domain protein - - - 0.00000000000000000000000000000000000006242 147.0
CSH2_k127_5590326_0 Type I site-specific restriction-modification system, R (Restriction) subunit and related K01156 - 3.1.21.5 0.0 1123.0
CSH2_k127_5590326_1 DNA methylase K07316 - 2.1.1.72 6.748e-287 919.0
CSH2_k127_5590326_2 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 1.15e-235 745.0
CSH2_k127_5590326_3 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 525.0
CSH2_k127_5590326_4 Amino acid permease K03294 - - 0.0000000000000000000000000000000003493 137.0
CSH2_k127_5592217_0 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 327.0
CSH2_k127_5592217_1 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000913 256.0
CSH2_k127_5592217_2 Insecticide toxin TcdB middle/N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000001601 229.0
CSH2_k127_5592248_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000001012 211.0
CSH2_k127_5592248_1 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000008207 211.0
CSH2_k127_5599877_0 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 346.0
CSH2_k127_5599877_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 315.0
CSH2_k127_5602286_0 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 572.0
CSH2_k127_5602286_1 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 443.0
CSH2_k127_5602286_2 Thioredoxin domain - - - 0.000000000000000003683 93.0
CSH2_k127_5606411_0 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000003481 193.0
CSH2_k127_5606411_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000001804 82.0
CSH2_k127_5606411_2 Protein involved in outer membrane biogenesis - - - 0.00000000001408 70.0
CSH2_k127_5615009_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 493.0
CSH2_k127_5615009_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000004881 166.0
CSH2_k127_5615009_2 peptidoglycan binding K03642 - - 0.000000000000000000000000000000000000000201 169.0
CSH2_k127_5615009_3 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000004011 147.0
CSH2_k127_5615009_4 Domain of unknown function (DUF4115) - - - 0.0000000003446 69.0
CSH2_k127_5689441_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 350.0
CSH2_k127_5689441_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001285 288.0
CSH2_k127_5689441_2 RND efflux system, outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009604 274.0
CSH2_k127_569977_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 6.664e-319 1016.0
CSH2_k127_570515_0 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 383.0
CSH2_k127_570515_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000003233 273.0
CSH2_k127_570515_2 Tetratricopeptide repeat - - - 0.00000000000000000006287 94.0
CSH2_k127_5717035_0 sigma-54 factor interaction domain-containing protein K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 479.0
CSH2_k127_5717035_1 PFAM type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 316.0
CSH2_k127_5717035_2 Aldolase K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000001755 184.0
CSH2_k127_5740119_0 BtpA family K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002399 253.0
CSH2_k127_5740119_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000007498 210.0
CSH2_k127_5740119_2 - - - - 0.0000000000000000000000000000000005349 139.0
CSH2_k127_5752300_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 503.0
CSH2_k127_5752300_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 453.0
CSH2_k127_5752300_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 388.0
CSH2_k127_5752300_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007731 245.0
CSH2_k127_5752300_4 Belongs to the UPF0173 family - - - 0.000000000000000000000000003392 114.0
CSH2_k127_575311_0 Peptidase family M3 K08602 - - 1.492e-249 788.0
CSH2_k127_575311_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 9.243e-228 730.0
CSH2_k127_575311_2 3-beta hydroxysteroid dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000177 265.0
CSH2_k127_575311_3 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000009868 187.0
CSH2_k127_575311_4 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000003413 180.0
CSH2_k127_575311_5 AMP binding - - - 0.00000000000000000000000000000002714 134.0
CSH2_k127_575311_6 Cysteine-rich CPXCG - - - 0.0000000006944 61.0
CSH2_k127_575311_7 Transmembrane proteins 14C - - - 0.000000008829 64.0
CSH2_k127_575311_8 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000008807 61.0
CSH2_k127_575311_9 Biopolymer transport protein ExbD/TolR K03559 - - 0.00002436 52.0
CSH2_k127_5762237_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.917e-275 865.0
CSH2_k127_5762237_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 461.0
CSH2_k127_5762237_2 Domain of unknown function (DUF5060) - - - 0.00000000000000000000000000000000000000000000000000000000000000005806 243.0
CSH2_k127_5762237_3 Belongs to the peptidase S1C family K04691,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000008509 209.0
CSH2_k127_5762237_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000002579 91.0
CSH2_k127_5777803_0 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000002288 243.0
CSH2_k127_5777803_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000002362 126.0
CSH2_k127_5787841_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 4.26e-196 623.0
CSH2_k127_5787841_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000006238 94.0
CSH2_k127_5787841_2 MMPL family K07003 - - 0.00000000003217 71.0
CSH2_k127_5801249_0 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 409.0
CSH2_k127_5828240_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 534.0
CSH2_k127_5828240_1 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000001895 251.0
CSH2_k127_5828240_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000001187 120.0
CSH2_k127_5828240_3 reductase K00059 - 1.1.1.100 0.00000000000000000000003818 99.0
CSH2_k127_5835196_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 7.772e-222 702.0
CSH2_k127_5835196_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 601.0
CSH2_k127_5835196_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 409.0
CSH2_k127_5835196_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 393.0
CSH2_k127_5835196_4 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000001359 218.0
CSH2_k127_584488_0 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000001036 245.0
CSH2_k127_584488_1 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000002597 165.0
CSH2_k127_584488_2 Serine carboxypeptidase - - - 0.000000000000000000000000000000001288 134.0
CSH2_k127_584488_3 WD domain, G-beta repeat - - - 0.000000000000000000005087 106.0
CSH2_k127_5877834_0 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 416.0
CSH2_k127_5877834_1 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001992 271.0
CSH2_k127_5877834_2 FAD linked oxidase K18930 - - 0.000000000000000000000001736 108.0
CSH2_k127_5904735_0 Glycosyl hydrolases family 2, TIM barrel domain K01190,K01195 GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494 3.2.1.23,3.2.1.31 1.092e-253 811.0
CSH2_k127_5904735_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 613.0
CSH2_k127_5926781_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 321.0
CSH2_k127_5935929_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.565e-237 747.0
CSH2_k127_5935929_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009198 561.0
CSH2_k127_5935929_2 PFAM Short-chain dehydrogenase reductase SDR K00046,K00065 - 1.1.1.127,1.1.1.69 0.000000000000000000000000000000000002687 146.0
CSH2_k127_5935929_3 Protein of unknown function (DUF433) - - - 0.0000000000000000009518 90.0
CSH2_k127_5935929_4 - - - - 0.00000000000002181 77.0
CSH2_k127_5935929_5 Glycosyl hydrolase family 88 - - - 0.00000000006492 72.0
CSH2_k127_5935929_6 Type III restriction enzyme, res subunit - - - 0.0002229 48.0
CSH2_k127_5935929_7 PFAM DNA methylase N-4 N-6 domain protein K07316 - 2.1.1.72 0.0003683 45.0
CSH2_k127_5954166_0 NAD synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 603.0
CSH2_k127_5954166_1 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 351.0
CSH2_k127_5954166_2 - - - - 0.00000000000000000000000000000000001012 148.0
CSH2_k127_5954166_3 Glycosyl transferase, family 2 - - - 0.0000000000000000009718 91.0
CSH2_k127_5986452_0 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1431.0
CSH2_k127_5986452_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 6.3e-294 910.0
CSH2_k127_5986452_2 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000005999 214.0
CSH2_k127_5997349_0 Major facilitator Superfamily K06902 - - 0.0000000000000000000000000000000000000000000000000000872 203.0
CSH2_k127_5997349_1 Protein of unknown function (DUF1559) - - - 0.00000000001133 74.0
CSH2_k127_5997349_2 Transposase - - - 0.00000008327 61.0
CSH2_k127_5997349_3 protein ubiquitination - - - 0.0003 49.0
CSH2_k127_6000980_0 Protein of unknown function (DUF1015) K00262 - 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 384.0
CSH2_k127_6000980_1 oxidoreductase activity - - - 0.000000000000000000000000000000001675 139.0
CSH2_k127_6035412_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 422.0
CSH2_k127_6035412_1 Protein of unknown function (DUF434) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001177 266.0
CSH2_k127_6035412_2 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000002934 231.0
CSH2_k127_6035900_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 525.0
CSH2_k127_6035900_1 ATP-dependent helicase C-terminal K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 456.0
CSH2_k127_6035900_2 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 413.0
CSH2_k127_6035900_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 381.0
CSH2_k127_6035900_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 314.0
CSH2_k127_6035900_5 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005648 281.0
CSH2_k127_6035900_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000004606 177.0
CSH2_k127_6035900_7 Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000003683 174.0
CSH2_k127_6035900_8 Smr domain - - - 0.000000000000000000000000000005564 123.0
CSH2_k127_6068888_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 586.0
CSH2_k127_6068888_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 413.0
CSH2_k127_6068888_2 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 347.0
CSH2_k127_6068888_3 WYL domain K13572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 299.0
CSH2_k127_6068888_4 Preprotein translocase subunit K03210 - - 0.00000000000000000001258 96.0
CSH2_k127_6129242_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 410.0
CSH2_k127_6159829_0 Major facilitator Superfamily K03289,K03301,K08218,K11537 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009987,GO:0015211,GO:0015212,GO:0015213,GO:0015214,GO:0015553,GO:0015858,GO:0015860,GO:0015861,GO:0015862,GO:0015863,GO:0015864,GO:0015893,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032238,GO:0034641,GO:0042221,GO:0042493,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072530,GO:0072531,GO:1901264,GO:1901360,GO:1901505,GO:1901642 - 0.0000000000000000000000000000000000000000000000000000000000000000001968 252.0
CSH2_k127_6159829_1 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.0000000000006111 75.0
CSH2_k127_6165687_0 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 305.0
CSH2_k127_6165687_1 COG3264 Small-conductance mechanosensitive channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001343 285.0
CSH2_k127_6165687_2 - - - - 0.000000000000000000000000000000000006402 142.0
CSH2_k127_6211279_0 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 326.0
CSH2_k127_6211279_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 290.0
CSH2_k127_6211279_2 PFAM von Willebrand factor type A domain K07114 - - 0.000001665 54.0
CSH2_k127_6217070_0 - - - - 0.000000005062 70.0
CSH2_k127_6240003_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004392 295.0
CSH2_k127_6240003_1 Proteins of 100 residues with WXG - - - 0.0000000000000000000000000000001434 129.0
CSH2_k127_6240003_2 - - - - 0.000000000000000000000000000001996 126.0
CSH2_k127_6240003_3 R3H domain - - - 0.0000000000000000000000007363 110.0
CSH2_k127_6240003_4 - - - - 0.000003847 53.0
CSH2_k127_624595_0 shikimate 3-dehydrogenase (NADP+) activity K00800,K10669 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19,2.7.1.160 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 408.0
CSH2_k127_624595_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000002661 213.0
CSH2_k127_624595_2 Cytidylate kinase K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000183 163.0
CSH2_k127_624595_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000802 145.0
CSH2_k127_6266299_0 MMPL family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 316.0
CSH2_k127_6266299_1 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000008883 172.0
CSH2_k127_6266299_2 - - - - 0.0000000000002432 79.0
CSH2_k127_6286489_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 397.0
CSH2_k127_6286489_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000167 233.0
CSH2_k127_6300810_0 xylanase chitin deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001504 269.0
CSH2_k127_6300810_1 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000002837 190.0
CSH2_k127_6300810_2 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K01802,K03772,K03773 - 5.2.1.8 0.000000000000000006205 83.0
CSH2_k127_6309146_0 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001149 278.0
CSH2_k127_6309146_1 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000003158 154.0
CSH2_k127_6309146_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000004113 132.0
CSH2_k127_635018_0 Phosphoenolpyruvate carboxylase K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 550.0
CSH2_k127_635018_1 Thimet oligopeptidase K01392,K01393 GO:0000209,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005829,GO:0006464,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0016567,GO:0016787,GO:0019538,GO:0023052,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032446,GO:0033218,GO:0034641,GO:0035556,GO:0036211,GO:0042277,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0070013,GO:0070647,GO:0071704,GO:0140096,GO:1901564 3.4.24.15,3.4.24.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 420.0
CSH2_k127_635018_2 5-(carboxyamino)imidazole ribonucleotide synthase activity K01589 GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 0.00000000000000000000000000000000000000000000000004379 185.0
CSH2_k127_6356277_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 396.0
CSH2_k127_6356277_1 Alpha/beta hydrolase family K01175 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006771 262.0
CSH2_k127_6356277_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000008247 201.0
CSH2_k127_6356277_3 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000004504 153.0
CSH2_k127_635719_0 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000001901 98.0
CSH2_k127_635719_1 KH domain K06960 - - 0.0000000000000006815 84.0
CSH2_k127_635719_2 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000002352 79.0
CSH2_k127_635719_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000457 55.0
CSH2_k127_6361625_0 TrkA-N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 516.0
CSH2_k127_6361625_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 500.0
CSH2_k127_6361625_2 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.00001996 51.0
CSH2_k127_6361625_3 - - - - 0.0003083 51.0
CSH2_k127_6373306_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 520.0
CSH2_k127_6373306_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 406.0
CSH2_k127_6373306_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 396.0
CSH2_k127_6373306_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000236 204.0
CSH2_k127_6373306_4 NifU-like N terminal domain - - - 0.00000000000000000000000000000000000000000000000000003846 191.0
CSH2_k127_6373306_5 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000001159 165.0
CSH2_k127_640014_0 ABC-type multidrug transport system ATPase K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 319.0
CSH2_k127_640014_1 von Willebrand factor, type A - - - 0.000000000000000000005433 108.0
CSH2_k127_640014_2 transmembrane transport - - - 0.0001156 51.0
CSH2_k127_6430520_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 524.0
CSH2_k127_6430520_1 TIGRFAM ATP-dependent DNA helicase, RecQ family K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 324.0
CSH2_k127_6430520_2 PFAM DUF218 domain - - - 0.000000000000000000000000000000000000000000000000004283 192.0
CSH2_k127_6430520_3 protein conserved in bacteria K09794 - - 0.000000004486 61.0
CSH2_k127_6430520_4 FUN14 family - - - 0.0001304 51.0
CSH2_k127_6443489_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008407 461.0
CSH2_k127_6443489_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 417.0
CSH2_k127_6443489_2 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K00773,K07319,K11782,K15461 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000009187 248.0
CSH2_k127_6443489_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.000000000000000001345 89.0
CSH2_k127_6459402_0 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 512.0
CSH2_k127_6459402_1 Erythromycin esterase - - - 0.000000000000001962 84.0
CSH2_k127_646873_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 492.0
CSH2_k127_646873_1 Amino acid kinase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 483.0
CSH2_k127_646873_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 342.0
CSH2_k127_646873_3 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000495 149.0
CSH2_k127_646873_5 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000001292 91.0
CSH2_k127_646873_6 Protein of unknown function (DUF1015) - - - 0.000000003952 63.0
CSH2_k127_6479277_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 507.0
CSH2_k127_6479277_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 364.0
CSH2_k127_6479277_2 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000000001033 93.0
CSH2_k127_6481417_0 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 390.0
CSH2_k127_6481417_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 361.0
CSH2_k127_6481417_2 FeS assembly SUF system protein SufT - - - 0.00000000000000000000000000000000000000000000000000000000008805 210.0
CSH2_k127_6481417_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000031 140.0
CSH2_k127_6488478_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1142.0
CSH2_k127_6488478_1 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 555.0
CSH2_k127_6488478_2 Alpha-glucan water dikinase K08244 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009266,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009607,GO:0009608,GO:0009610,GO:0009620,GO:0009628,GO:0009631,GO:0009941,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0031967,GO:0031975,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050521,GO:0050896,GO:0051704,GO:0051707,GO:0071704,GO:1901575 2.7.9.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 355.0
CSH2_k127_6488478_3 Putative restriction endonuclease - - - 0.0000000000001243 77.0
CSH2_k127_6488478_4 Xylose isomerase-like TIM barrel - - - 0.0001312 54.0
CSH2_k127_6490109_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.243e-317 997.0
CSH2_k127_6490109_1 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 2.48e-258 814.0
CSH2_k127_6490109_2 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 540.0
CSH2_k127_6490109_3 Belongs to the precorrin methyltransferase family K02303,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 464.0
CSH2_k127_6490109_4 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001118 235.0
CSH2_k127_6490109_5 DEAD DEAH box helicase - - - 0.000000000000000000000000000000000000000001074 157.0
CSH2_k127_6490109_6 Oxygen tolerance - - - 0.0000000000000000000000000000000001187 151.0
CSH2_k127_6503004_0 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 463.0
CSH2_k127_6503004_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000007894 194.0
CSH2_k127_6518924_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 416.0
CSH2_k127_6518924_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 435.0
CSH2_k127_6518924_2 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000001114 220.0
CSH2_k127_65363_0 - - - - 0.0000000000004004 81.0
CSH2_k127_65363_1 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000004047 75.0
CSH2_k127_6601531_0 TIGRFAM autotransporter-associated beta strand repeat protein - - - 0.000000000000001573 91.0
CSH2_k127_6618915_0 ATP-dependent peptidase activity K01338 - 3.4.21.53 7.945e-261 826.0
CSH2_k127_6618915_1 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K05586 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000002164 227.0
CSH2_k127_6618915_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000001161 94.0
CSH2_k127_6618915_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000001443 64.0
CSH2_k127_6618915_4 NADH ubiquinone oxidoreductase NADH-binding (51 kD) subunit K05587 - 1.6.5.3 0.00002848 47.0
CSH2_k127_6637926_0 V-type ATPase 116kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 373.0
CSH2_k127_6637926_1 subunit (C K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 306.0
CSH2_k127_6637926_2 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000785 179.0
CSH2_k127_6637926_3 - - - - 0.00000000001817 71.0
CSH2_k127_6647801_0 Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000001712 198.0
CSH2_k127_6690245_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 289.0
CSH2_k127_6690245_1 Type I restriction-modification system methyltransferase subunit - - - 0.00000000000000000000000000000000000000000000000000000000000001564 226.0
CSH2_k127_6690245_2 - - - - 0.00000000000000000000000000000000000000000000000000003981 195.0
CSH2_k127_6690245_3 Protein of unknown function (DUF2283) - - - 0.000000000000000000001114 96.0
CSH2_k127_6698063_0 Kelch motif - - - 0.0000000000000000000000000000000000000000000000004859 194.0
CSH2_k127_6698063_1 DNA polymerase beta domain protein region K07075 - - 0.000000000000001048 83.0
CSH2_k127_6698063_2 Protein of unknown function DUF86 - - - 0.0000000001387 68.0
CSH2_k127_6698063_3 Thrombospondin type 3 repeat - - - 0.00000193 60.0
CSH2_k127_6698063_4 domain protein K20811 - 2.4.1.9 0.000005899 59.0
CSH2_k127_6700174_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 337.0
CSH2_k127_6716089_0 Belongs to the carbamoyltransferase HypF family K04656 - - 3.94e-276 872.0
CSH2_k127_6716089_1 Glutamine amidotransferase domain - - - 2.998e-241 760.0
CSH2_k127_6716089_2 MreB/Mbl protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 630.0
CSH2_k127_6716089_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 512.0
CSH2_k127_6716089_4 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000001171 230.0
CSH2_k127_6716089_5 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000006367 164.0
CSH2_k127_6716089_6 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000004047 117.0
CSH2_k127_6716089_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000006138 105.0
CSH2_k127_6716089_8 Ribosomal protein L34 K02914 - - 0.00000002883 59.0
CSH2_k127_6716089_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000009179 55.0
CSH2_k127_6718210_0 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 469.0
CSH2_k127_6718210_1 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 379.0
CSH2_k127_6718210_2 Belongs to the type II topoisomerase GyrA ParC subunit family K02621 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 319.0
CSH2_k127_6718210_3 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000007799 96.0
CSH2_k127_6744581_0 UTP--glucose-1-phosphate uridylyltransferase - - - 0.0 1046.0
CSH2_k127_6744581_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 306.0
CSH2_k127_6744581_2 UTP--glucose-1-phosphate uridylyltransferase - - - 0.00000008557 61.0
CSH2_k127_6744598_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 458.0
CSH2_k127_6744598_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 368.0
CSH2_k127_6746145_0 Belongs to the DegT DnrJ EryC1 family K13010,K19715 - 2.6.1.102,2.6.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 511.0
CSH2_k127_6746145_1 PFAM Iron-containing alcohol dehydrogenase K19714 - 1.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 458.0
CSH2_k127_6746145_2 Cytidylyltransferase K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 293.0
CSH2_k127_6746145_3 Addiction module toxin, RelE StbE family - - - 0.00000000000000000000000000000233 124.0
CSH2_k127_6746145_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.0000000002588 62.0
CSH2_k127_6746624_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 382.0
CSH2_k127_6746624_1 tetratricopeptide repeat - - - 0.0000000000000000000445 100.0
CSH2_k127_677724_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 535.0
CSH2_k127_677724_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006731 275.0
CSH2_k127_677724_2 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000006865 149.0
CSH2_k127_677724_3 ECF sigma factor - - - 0.000000000000000000418 90.0
CSH2_k127_677724_4 Belongs to the peptidase S8 family - - - 0.000000000000000003112 91.0
CSH2_k127_677724_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000003482 59.0
CSH2_k127_714126_0 PFAM Glycoside hydrolase family 42 domain protein K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 497.0
CSH2_k127_714126_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000001085 196.0
CSH2_k127_714126_2 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000003629 57.0
CSH2_k127_78114_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 514.0
CSH2_k127_78114_1 TIGRFAM RHS repeat-associated core domain - - - 0.00000009865 63.0
CSH2_k127_789476_0 Protein export membrane protein K03296,K18138 - - 1.425e-230 735.0
CSH2_k127_789476_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 426.0
CSH2_k127_789476_2 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003858 263.0
CSH2_k127_797942_0 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 389.0
CSH2_k127_797942_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 299.0
CSH2_k127_797942_2 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000002379 200.0
CSH2_k127_797942_3 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000151 199.0
CSH2_k127_797942_4 Helix-turn-helix domain K03892,K21903 - - 0.000000000000000000000001378 109.0
CSH2_k127_805379_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 7.152e-203 638.0
CSH2_k127_805379_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 2.603e-195 623.0
CSH2_k127_805379_2 NADH dehydrogenase K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 511.0
CSH2_k127_805379_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002364 256.0
CSH2_k127_805379_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000002049 152.0
CSH2_k127_805379_5 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000000000000000000000000000000009017 145.0
CSH2_k127_805379_6 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0002896 45.0
CSH2_k127_821567_0 Domain of unknown function (DUF5127) - - - 5.494e-222 710.0
CSH2_k127_821567_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000886 239.0
CSH2_k127_878289_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 516.0
CSH2_k127_878289_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00381 - 1.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 482.0
CSH2_k127_878289_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000001626 101.0
CSH2_k127_878289_2 Glutaminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 451.0
CSH2_k127_878289_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 436.0
CSH2_k127_878289_4 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 322.0
CSH2_k127_878289_5 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 289.0
CSH2_k127_878289_6 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002259 258.0
CSH2_k127_878289_7 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000003224 234.0
CSH2_k127_878289_8 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000003919 192.0
CSH2_k127_878289_9 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000002161 183.0
CSH2_k127_893515_0 COG0768 cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 301.0
CSH2_k127_897295_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.294e-275 860.0
CSH2_k127_897295_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 441.0
CSH2_k127_897295_2 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 337.0
CSH2_k127_903797_0 protein flavinylation K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000001139 238.0
CSH2_k127_903797_1 Rhomboid family - - - 0.000000000000000000000000000000000004152 145.0
CSH2_k127_920239_0 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 350.0
CSH2_k127_920239_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000004695 67.0
CSH2_k127_920650_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 435.0
CSH2_k127_920650_1 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 311.0
CSH2_k127_920650_2 - - - - 0.000000000000000000000952 102.0
CSH2_k127_920650_3 TPR Domain containing protein - - - 0.0000003881 63.0
CSH2_k127_920650_4 - - - - 0.00008728 52.0
CSH2_k127_933617_0 trans-aconitate 2-methyltransferase activity K00598,K02169 - 2.1.1.144,2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000001218 269.0
CSH2_k127_933617_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000003163 220.0
CSH2_k127_933617_2 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000001352 218.0
CSH2_k127_933617_3 - K07484 - - 0.00000000000002867 76.0
CSH2_k127_962337_0 AcrB/AcrD/AcrF family - - - 2.2e-235 744.0
CSH2_k127_962337_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000007357 228.0
CSH2_k127_97702_0 DEAD DEAH box helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 338.0