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Overview

ID MAG00621
Name CSH2_bin.7
Sample SMP0014
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class E2
Order DHVEG-1
Family DHVEG-1
Genus SM1-50
Species SM1-50 sp025457885
Assembly information
Completeness (%) 81.15
Contamination (%) 1.58
GC content (%) 45.0
N50 (bp) 23,378
Genome size (bp) 1,557,984

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1312

Gene name Description KEGG GOs EC E-value Score Sequence
CSH2_k127_1002533_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007109 268.0
CSH2_k127_1002533_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000004751 192.0
CSH2_k127_1002533_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000002504 111.0
CSH2_k127_1093313_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 456.0
CSH2_k127_1093313_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 367.0
CSH2_k127_1093313_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001096 273.0
CSH2_k127_1093313_3 - K03561,K12287 - - 0.0000000000000000000000000000000000000001732 175.0
CSH2_k127_1093313_4 membrane - - - 0.00000000000000000000000000000000007241 143.0
CSH2_k127_1093313_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000009884 87.0
CSH2_k127_1093313_6 Right handed beta helix region - - - 0.000000001132 70.0
CSH2_k127_1152363_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 490.0
CSH2_k127_1152363_1 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 391.0
CSH2_k127_1152363_10 LacY proton/sugar symporter - - - 0.0000000000000007859 89.0
CSH2_k127_1152363_11 - - - - 0.0006817 46.0
CSH2_k127_1152363_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 284.0
CSH2_k127_1152363_3 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002822 243.0
CSH2_k127_1152363_4 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000007219 209.0
CSH2_k127_1152363_5 - - - - 0.00000000000000000000000000000000000002121 162.0
CSH2_k127_1152363_6 cellulose binding - - - 0.000000000000000000000001807 119.0
CSH2_k127_1152363_7 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.000000000000000000007921 108.0
CSH2_k127_1152363_8 Domain of unknown function (DUF1805) - - - 0.000000000000000003556 88.0
CSH2_k127_1152363_9 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000003898 82.0
CSH2_k127_1256044_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 3.6.3.54 9.535e-269 851.0
CSH2_k127_1256044_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 437.0
CSH2_k127_1256044_10 PFAM zinc iron permease K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004236 252.0
CSH2_k127_1256044_11 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000008512 237.0
CSH2_k127_1256044_12 TIGRFAM PAS sensor protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001215 242.0
CSH2_k127_1256044_13 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000001934 240.0
CSH2_k127_1256044_14 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000005738 228.0
CSH2_k127_1256044_15 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.000000000000000000000000000000000000000000000000000000000006827 214.0
CSH2_k127_1256044_16 thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000022 211.0
CSH2_k127_1256044_17 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000007773 215.0
CSH2_k127_1256044_19 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000000000000000000000000003796 218.0
CSH2_k127_1256044_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 399.0
CSH2_k127_1256044_20 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000005066 190.0
CSH2_k127_1256044_21 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000009595 179.0
CSH2_k127_1256044_22 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000000000002553 176.0
CSH2_k127_1256044_23 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000002741 164.0
CSH2_k127_1256044_24 pyridoxamine 5'-phosphate oxidase-related FMN-binding K07005 - - 0.00000000000000000000000000000000000000008779 156.0
CSH2_k127_1256044_25 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000000000000002478 163.0
CSH2_k127_1256044_26 NUDIX domain - - - 0.00000000000000000000000000000000002645 139.0
CSH2_k127_1256044_27 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000004021 135.0
CSH2_k127_1256044_28 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000001068 129.0
CSH2_k127_1256044_29 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000001446 122.0
CSH2_k127_1256044_3 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 362.0
CSH2_k127_1256044_30 AraC-like ligand binding domain - - - 0.000000000000000000000000000002722 124.0
CSH2_k127_1256044_31 PQQ enzyme repeat - - - 0.00000000000000000000000001361 126.0
CSH2_k127_1256044_32 - - - - 0.0000000000000000000000001747 112.0
CSH2_k127_1256044_33 phosphorelay signal transduction system K07658 - - 0.00000000000000000000005398 102.0
CSH2_k127_1256044_34 YHS domain - - - 0.000000000000000000002084 93.0
CSH2_k127_1256044_35 Peptidase_C39 like family - - - 0.000000000000000000003819 100.0
CSH2_k127_1256044_36 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000005619 92.0
CSH2_k127_1256044_37 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000033 82.0
CSH2_k127_1256044_38 Major facilitator Superfamily K08162,K08226,K16211 - - 0.00000000000002889 85.0
CSH2_k127_1256044_39 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.000000000001529 73.0
CSH2_k127_1256044_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 346.0
CSH2_k127_1256044_40 Sterol carrier protein - - - 0.000000000005943 71.0
CSH2_k127_1256044_41 Periplasmic copper-binding protein (NosD) - - - 0.0000000002375 72.0
CSH2_k127_1256044_42 signal transduction protein with CBS domains - - - 0.0000000005158 71.0
CSH2_k127_1256044_43 Beta-galactosidase - - - 0.0000000005389 73.0
CSH2_k127_1256044_44 membrane-associated protein domain - - - 0.000000001563 70.0
CSH2_k127_1256044_45 glucose sorbosone - - - 0.00000002467 64.0
CSH2_k127_1256044_46 Bacterial Ig-like domain (group 3) - - - 0.0000001356 64.0
CSH2_k127_1256044_47 In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha- aminoadipate (AAA) pathway K06154 - - 0.0000008643 60.0
CSH2_k127_1256044_48 lycopene cyclase - - - 0.00000214 54.0
CSH2_k127_1256044_49 membrane-associated protein domain - - - 0.000006734 59.0
CSH2_k127_1256044_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 349.0
CSH2_k127_1256044_50 COG1522 Transcriptional regulators - - - 0.00001129 57.0
CSH2_k127_1256044_6 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 346.0
CSH2_k127_1256044_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 340.0
CSH2_k127_1256044_8 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 306.0
CSH2_k127_1256044_9 threonine synthase activity K01733,K15527 - 2.5.1.76,4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 297.0
CSH2_k127_1348954_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 360.0
CSH2_k127_1348954_1 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001007 254.0
CSH2_k127_1348954_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000008674 203.0
CSH2_k127_1348954_3 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000006653 137.0
CSH2_k127_1348954_4 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000000000000000000000007512 131.0
CSH2_k127_1348954_5 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000002439 60.0
CSH2_k127_1348954_6 Bacterial PH domain - - - 0.0004605 52.0
CSH2_k127_1412769_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 6.932e-197 624.0
CSH2_k127_1412769_1 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000004974 199.0
CSH2_k127_1412769_2 - - - - 0.000000000000000000000000000000001449 136.0
CSH2_k127_1412769_3 membrane-associated protein domain - - - 0.0000000002756 68.0
CSH2_k127_1468749_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 602.0
CSH2_k127_1468749_1 aminopeptidase K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 422.0
CSH2_k127_1468749_10 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.000000000000000000000000000000000000001389 168.0
CSH2_k127_1468749_11 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000001941 156.0
CSH2_k127_1468749_12 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000004057 140.0
CSH2_k127_1468749_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000001849 133.0
CSH2_k127_1468749_14 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000001973 136.0
CSH2_k127_1468749_15 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000005238 119.0
CSH2_k127_1468749_16 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000005088 112.0
CSH2_k127_1468749_17 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.00000000000000000000000000542 123.0
CSH2_k127_1468749_18 aminopeptidase activity K05994 - 3.4.11.10 0.000000000000000000001067 109.0
CSH2_k127_1468749_19 response regulator, receiver K07668,K07669 - - 0.000000000000000000001901 98.0
CSH2_k127_1468749_2 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 411.0
CSH2_k127_1468749_20 Peptidase family M28 K04771 - 3.4.21.107 0.000000000000000000007879 106.0
CSH2_k127_1468749_21 Papain family cysteine protease - - - 0.00000000000000000004625 105.0
CSH2_k127_1468749_22 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.00000000000000001414 98.0
CSH2_k127_1468749_23 Propeptide_C25 - - - 0.0000000000000001238 94.0
CSH2_k127_1468749_24 PFAM Peptidase C1A, papain - - - 0.0000000000000008551 91.0
CSH2_k127_1468749_25 Psort location Cytoplasmic, score - - - 0.00000000000000105 77.0
CSH2_k127_1468749_26 Archaeal Type IV pilin, N-terminal - - - 0.00000000000001451 87.0
CSH2_k127_1468749_27 protein contain chitin-binding domain type 3 - - - 0.00000000000002166 87.0
CSH2_k127_1468749_28 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000006653 82.0
CSH2_k127_1468749_29 Sugar (and other) transporter K08196,K08369 - - 0.0000000001909 73.0
CSH2_k127_1468749_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 318.0
CSH2_k127_1468749_30 PFAM conserved K07027 - - 0.0000000002347 72.0
CSH2_k127_1468749_31 Lrp/AsnC ligand binding domain - - - 0.000000006327 59.0
CSH2_k127_1468749_32 Transglutaminase-like superfamily - - - 0.0000008118 61.0
CSH2_k127_1468749_33 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.000008651 58.0
CSH2_k127_1468749_34 COG1522 Transcriptional regulators K03719 - - 0.0002641 50.0
CSH2_k127_1468749_35 Belongs to the peptidase S8 family - - - 0.0004478 54.0
CSH2_k127_1468749_36 Transglutaminase/protease-like homologues - - - 0.0009857 51.0
CSH2_k127_1468749_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000003802 207.0
CSH2_k127_1468749_5 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000002923 190.0
CSH2_k127_1468749_6 Pas domain - - - 0.000000000000000000000000000000000000000000000005164 183.0
CSH2_k127_1468749_7 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000131 166.0
CSH2_k127_1468749_8 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000003123 186.0
CSH2_k127_1468749_9 PFAM NAD dependent epimerase dehydratase family - - - 0.00000000000000000000000000000000000000008328 165.0
CSH2_k127_1683556_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.0 1135.0
CSH2_k127_1683556_1 phosphoenolpyruvate carboxykinase (GTP) activity K01596,K01610 - 4.1.1.32,4.1.1.49 1.144e-239 755.0
CSH2_k127_1683556_10 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001141 266.0
CSH2_k127_1683556_11 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000001259 239.0
CSH2_k127_1683556_12 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000001874 232.0
CSH2_k127_1683556_13 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000004049 212.0
CSH2_k127_1683556_14 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000000007321 212.0
CSH2_k127_1683556_15 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000001617 204.0
CSH2_k127_1683556_16 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000001999 191.0
CSH2_k127_1683556_17 S-acyltransferase activity K00627,K03310,K03578,K12132 - 2.3.1.12,2.7.11.1,3.6.4.13 0.000000000000000000000000000000000000000000000000008962 193.0
CSH2_k127_1683556_18 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000003078 190.0
CSH2_k127_1683556_19 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000002842 168.0
CSH2_k127_1683556_2 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 605.0
CSH2_k127_1683556_20 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000008591 145.0
CSH2_k127_1683556_21 Predicted SAM-dependent RNA methyltransferase - - - 0.0000000000000000000000000000002573 132.0
CSH2_k127_1683556_22 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 0.000000000000000000000000002055 119.0
CSH2_k127_1683556_23 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000000000000000000002198 124.0
CSH2_k127_1683556_24 Rhomboid family - - - 0.000000000000000000000003046 114.0
CSH2_k127_1683556_25 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000000000006966 91.0
CSH2_k127_1683556_26 Zinc metalloprotease (Elastase) - - - 0.000000000000000001005 100.0
CSH2_k127_1683556_27 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000001775 92.0
CSH2_k127_1683556_28 PFAM Nitroreductase - - - 0.000000000000002603 89.0
CSH2_k127_1683556_29 Micrococcal nuclease (thermonuclease) homologs K01174,K02238 - 3.1.31.1 0.0000000186 68.0
CSH2_k127_1683556_3 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 597.0
CSH2_k127_1683556_30 APHP domain protein - - - 0.0000009809 60.0
CSH2_k127_1683556_31 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000005157 58.0
CSH2_k127_1683556_4 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 558.0
CSH2_k127_1683556_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147,K22465 - 4.1.99.17,4.1.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 488.0
CSH2_k127_1683556_6 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 370.0
CSH2_k127_1683556_7 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 343.0
CSH2_k127_1683556_8 deoxyribonuclease I activity K06131,K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 347.0
CSH2_k127_1683556_9 ABC transporter K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 317.0
CSH2_k127_1734037_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 414.0
CSH2_k127_1734037_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 324.0
CSH2_k127_1734037_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000001598 162.0
CSH2_k127_1734037_3 Pfam:DUF552 K09152 - - 0.00000000000000000000000004994 111.0
CSH2_k127_1762181_0 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 340.0
CSH2_k127_1762181_1 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 309.0
CSH2_k127_1762181_2 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 302.0
CSH2_k127_1762181_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 288.0
CSH2_k127_1762181_4 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000001102 214.0
CSH2_k127_1762181_5 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000007753 138.0
CSH2_k127_1762181_6 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000000000000000000001301 121.0
CSH2_k127_1762181_7 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000001775 118.0
CSH2_k127_1762181_8 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0001465 50.0
CSH2_k127_181451_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 473.0
CSH2_k127_181451_1 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 297.0
CSH2_k127_181451_10 PFAM PKD domain containing protein - - - 0.0000000000000002242 89.0
CSH2_k127_181451_11 methyltransferase activity - - - 0.0000000000000151 81.0
CSH2_k127_181451_12 Parallel beta-helix - - - 0.00000000004474 76.0
CSH2_k127_181451_13 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0007616 52.0
CSH2_k127_181451_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000006091 198.0
CSH2_k127_181451_3 Radical SAM - - - 0.0000000000000000000000000000000000000117 154.0
CSH2_k127_181451_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000004829 128.0
CSH2_k127_181451_5 PFAM periplasmic copper-binding - - - 0.0000000000000000000000000003109 134.0
CSH2_k127_181451_6 KaiC - - - 0.0000000000000000000000000003986 123.0
CSH2_k127_181451_7 cheY-homologous receiver domain K07668 - - 0.00000000000000000000000007575 110.0
CSH2_k127_181451_8 PFAM periplasmic copper-binding - - - 0.00000000000000000000004363 115.0
CSH2_k127_181451_9 Circadian clock protein KaiC - - - 0.000000000000000000002145 104.0
CSH2_k127_1865622_0 Heat shock 70 kDa protein K04043 - - 2.227e-241 760.0
CSH2_k127_1865622_1 PFAM PKD domain containing protein - - - 0.000000000000000000008049 105.0
CSH2_k127_1865622_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000002481 95.0
CSH2_k127_1865622_3 Universal stress protein family - - - 0.00000000000001501 79.0
CSH2_k127_1865622_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000006376 71.0
CSH2_k127_1869864_0 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 305.0
CSH2_k127_1994743_0 flavodoxin nitric oxide synthase - - - 3.279e-196 617.0
CSH2_k127_1994743_1 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000006559 181.0
CSH2_k127_1995330_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 577.0
CSH2_k127_1995330_1 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000009946 248.0
CSH2_k127_1995330_2 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000001391 235.0
CSH2_k127_1995330_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000002399 206.0
CSH2_k127_1995330_4 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000007252 177.0
CSH2_k127_1995330_5 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000002862 148.0
CSH2_k127_1995330_6 protein conserved in archaea - - - 0.00000000000000001501 87.0
CSH2_k127_1995330_7 metallopeptidase activity - - - 0.0000000000000004164 89.0
CSH2_k127_1995330_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0000000000008283 71.0
CSH2_k127_1999780_0 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005691 260.0
CSH2_k127_1999780_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001228 226.0
CSH2_k127_1999780_2 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000007955 226.0
CSH2_k127_1999780_3 glucosylceramidase activity - - - 0.00000000000000000001348 94.0
CSH2_k127_1999780_4 TfoX N-terminal domain - - - 0.0000000005531 64.0
CSH2_k127_2160089_0 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 365.0
CSH2_k127_2160089_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000001937 201.0
CSH2_k127_2160089_2 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000002602 189.0
CSH2_k127_2160089_3 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000004285 74.0
CSH2_k127_2160089_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000003982 64.0
CSH2_k127_2160089_5 membrane - - - 0.00000004278 63.0
CSH2_k127_2441166_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003083 274.0
CSH2_k127_2441166_1 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000004906 158.0
CSH2_k127_2441166_2 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992,K19341 - - 0.0000000000000000000000000000000000000000436 162.0
CSH2_k127_2441166_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002192 148.0
CSH2_k127_2441166_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002684 144.0
CSH2_k127_2441166_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000001277 84.0
CSH2_k127_2441166_6 amine dehydrogenase activity - - - 0.00000000000002216 85.0
CSH2_k127_2441166_7 amine dehydrogenase activity - - - 0.00000000002344 77.0
CSH2_k127_2441166_8 protein conserved in archaea - - - 0.000000001085 70.0
CSH2_k127_2441166_9 Domain of unknown function (DUF4389) - - - 0.000003288 57.0
CSH2_k127_2534507_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001374 260.0
CSH2_k127_2534507_1 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.000000000000000000000000000000000000002867 157.0
CSH2_k127_2553488_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 6.502e-218 689.0
CSH2_k127_2553488_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.398e-209 666.0
CSH2_k127_2553488_10 SIS domain K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000001949 147.0
CSH2_k127_2553488_11 Lysine exporter protein LysE YggA - - - 0.0000000000000000000000000000000000007985 148.0
CSH2_k127_2553488_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000001047 140.0
CSH2_k127_2553488_13 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000007059 103.0
CSH2_k127_2553488_14 Uncharacterised protein family (UPF0147) K09721 - - 0.00000000000000000000001967 101.0
CSH2_k127_2553488_15 parallel beta-helix repeat K03671 - - 0.0000000000000000168 94.0
CSH2_k127_2553488_16 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000002729 74.0
CSH2_k127_2553488_17 Conserved repeat domain - - - 0.000000001062 71.0
CSH2_k127_2553488_2 helicase superfamily c-terminal domain K10896 - - 5.055e-206 665.0
CSH2_k127_2553488_3 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 403.0
CSH2_k127_2553488_4 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 336.0
CSH2_k127_2553488_5 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 325.0
CSH2_k127_2553488_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002084 286.0
CSH2_k127_2553488_7 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000008642 226.0
CSH2_k127_2553488_8 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000003992 217.0
CSH2_k127_2553488_9 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000001258 194.0
CSH2_k127_2554104_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.833e-298 940.0
CSH2_k127_2554104_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.431e-274 863.0
CSH2_k127_2554104_2 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 502.0
CSH2_k127_2554104_3 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 368.0
CSH2_k127_2554104_4 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000002721 191.0
CSH2_k127_2554104_5 Belongs to the UPF0178 family - - - 0.000000000000000000000000000000000000000003916 158.0
CSH2_k127_2554104_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.00000000000000000000000000000000000000001027 167.0
CSH2_k127_2554104_7 4 iron, 4 sulfur cluster binding K00196 - - 0.000000000000000000000000000000001266 135.0
CSH2_k127_2554104_8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000002313 137.0
CSH2_k127_2554104_9 GPR1 FUN34 yaaH family protein K07034 - - 0.000000000000000000000000003452 119.0
CSH2_k127_2561817_0 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 352.0
CSH2_k127_2561817_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 355.0
CSH2_k127_2561817_2 arsenite transmembrane transporter activity K03893 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.00000000000000000000000000000000000000000000000000000006617 207.0
CSH2_k127_2561817_3 B12 binding domain K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000006687 213.0
CSH2_k127_2561817_4 - - - - 0.000000000000000000000000000000000000007363 168.0
CSH2_k127_2561817_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000001296 132.0
CSH2_k127_2561817_6 - - - - 0.000000000000000001875 98.0
CSH2_k127_2561817_7 Peptidase C10 family - - - 0.0000000000000000476 96.0
CSH2_k127_2561817_8 - - - - 0.0002762 51.0
CSH2_k127_2699002_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000002528 237.0
CSH2_k127_2699002_1 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000000000000001414 128.0
CSH2_k127_2699002_2 - - - - 0.000000009816 69.0
CSH2_k127_2699002_3 N-terminal 7TM region of histidine kinase - - - 0.000005591 57.0
CSH2_k127_2699002_4 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00009655 52.0
CSH2_k127_2704755_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000008273 158.0
CSH2_k127_2704755_1 ABC-2 type transporter K01992 - - 0.0000000000008185 80.0
CSH2_k127_2714905_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 413.0
CSH2_k127_2714905_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000001311 134.0
CSH2_k127_2714905_2 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000003913 106.0
CSH2_k127_2714905_3 parallel beta-helix repeat K03671 - - 0.0000000000000002777 91.0
CSH2_k127_2714905_4 Autotransporter beta-domain - - - 0.000005188 57.0
CSH2_k127_2741564_0 Cation transporter/ATPase, N-terminus K01537 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 555.0
CSH2_k127_2741564_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 496.0
CSH2_k127_2741564_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 299.0
CSH2_k127_2741564_3 GDSL-like Lipase/Acylhydrolase family K02014 - - 0.000000000000008071 86.0
CSH2_k127_2744930_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 460.0
CSH2_k127_2744930_1 dipeptide transport K02035 - - 0.000000000000000000107 92.0
CSH2_k127_2808823_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 3.973e-203 654.0
CSH2_k127_2808823_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 510.0
CSH2_k127_2808823_2 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000001146 196.0
CSH2_k127_2808823_3 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000000000000000002194 149.0
CSH2_k127_2808823_4 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000007208 143.0
CSH2_k127_2808823_5 Papain family cysteine protease - - - 0.0000000000000000004052 100.0
CSH2_k127_2810673_0 by modhmm K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 328.0
CSH2_k127_2810673_1 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 323.0
CSH2_k127_2810673_2 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 298.0
CSH2_k127_2810673_3 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000009085 84.0
CSH2_k127_2825342_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 563.0
CSH2_k127_2825342_1 ATP citrate synthase activity K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 546.0
CSH2_k127_2825342_2 aconitate hydratase K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 505.0
CSH2_k127_2938159_0 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000418 240.0
CSH2_k127_2938159_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K06987,K07752 - 3.4.17.18,3.4.17.22 0.00000000000000000000000000000000000000000000000000000000008036 230.0
CSH2_k127_2938159_2 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000001188 148.0
CSH2_k127_2938159_3 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000000000000000005501 109.0
CSH2_k127_2938159_4 response regulator, receiver K01768,K11527,K19617 - 2.7.13.3,4.6.1.1 0.000000000000000000007423 96.0
CSH2_k127_2938159_5 PFAM NHL repeat containing protein - - - 0.0000000000000001996 94.0
CSH2_k127_2938159_6 CarboxypepD_reg-like domain K13276 - - 0.00000001369 67.0
CSH2_k127_2992651_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 373.0
CSH2_k127_2992651_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001 272.0
CSH2_k127_2992651_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000001196 218.0
CSH2_k127_2992651_3 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000001378 170.0
CSH2_k127_2992651_4 aminopeptidase activity - - - 0.000002161 60.0
CSH2_k127_2992651_5 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0004524 52.0
CSH2_k127_3144005_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002786 274.0
CSH2_k127_3144005_1 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001533 269.0
CSH2_k127_3144005_2 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000003157 205.0
CSH2_k127_3144005_3 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000000001344 182.0
CSH2_k127_3144005_4 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.000000000000000000000000000000000000000000002903 170.0
CSH2_k127_3144005_5 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000001001 124.0
CSH2_k127_3144005_6 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000001856 87.0
CSH2_k127_3144005_7 response regulator receiver K02657 - - 0.00000033 57.0
CSH2_k127_3201408_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 6.112e-239 745.0
CSH2_k127_3201408_1 PFAM AMP-dependent synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 568.0
CSH2_k127_3201408_10 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002328 225.0
CSH2_k127_3201408_11 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000003186 214.0
CSH2_k127_3201408_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000003081 212.0
CSH2_k127_3201408_13 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000005855 203.0
CSH2_k127_3201408_14 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000005533 188.0
CSH2_k127_3201408_15 CBS domain K03498 - - 0.0000000000000000000000000000000000000000000000001929 194.0
CSH2_k127_3201408_16 amino acid activation for nonribosomal peptide biosynthetic process K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000397 199.0
CSH2_k127_3201408_17 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000001418 183.0
CSH2_k127_3201408_18 K -dependent Na Ca K07301 - - 0.000000000000000000000000000000000000000000000007998 184.0
CSH2_k127_3201408_19 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000001588 166.0
CSH2_k127_3201408_2 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 465.0
CSH2_k127_3201408_20 TraB family - - - 0.000000000000000000000000000000000004841 146.0
CSH2_k127_3201408_21 - - - - 0.0000000000000000000000000000000001294 134.0
CSH2_k127_3201408_22 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.0000000000000000000000000000000001393 151.0
CSH2_k127_3201408_23 Cupin domain - - - 0.0000000000000000000000000000001809 128.0
CSH2_k127_3201408_24 Papain family cysteine protease K11751,K14647 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000005237 130.0
CSH2_k127_3201408_25 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000007282 113.0
CSH2_k127_3201408_26 metallopeptidase activity K01181,K05994 - 3.2.1.8,3.4.11.10 0.00000000000000000000009885 113.0
CSH2_k127_3201408_27 PQQ-like domain - - - 0.000000000000000007509 98.0
CSH2_k127_3201408_28 COG3420 Nitrous oxidase accessory protein K07218 - - 0.000000000000001051 89.0
CSH2_k127_3201408_29 Periplasmic copper-binding protein (NosD) - - - 0.00000000000001569 87.0
CSH2_k127_3201408_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 462.0
CSH2_k127_3201408_30 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000002452 86.0
CSH2_k127_3201408_31 cell wall organization - - - 0.0000000000001139 84.0
CSH2_k127_3201408_32 cell wall organization - - - 0.0000000000003198 82.0
CSH2_k127_3201408_33 - - - - 0.0000000000005538 75.0
CSH2_k127_3201408_34 PFAM UspA domain protein - - - 0.000000000005943 71.0
CSH2_k127_3201408_35 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000002653 73.0
CSH2_k127_3201408_36 Transglutaminase-like superfamily - - - 0.0000000003602 70.0
CSH2_k127_3201408_37 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000006119 72.0
CSH2_k127_3201408_38 Peptidase family C25 - - - 0.000000004641 68.0
CSH2_k127_3201408_39 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000002398 67.0
CSH2_k127_3201408_4 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 432.0
CSH2_k127_3201408_40 - - - - 0.000005307 51.0
CSH2_k127_3201408_5 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000889 428.0
CSH2_k127_3201408_6 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 422.0
CSH2_k127_3201408_7 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 417.0
CSH2_k127_3201408_8 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 307.0
CSH2_k127_3201408_9 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000001046 247.0
CSH2_k127_3201681_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.0 1154.0
CSH2_k127_3201681_1 FMN binding - - - 5.93e-244 763.0
CSH2_k127_3201681_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 2.464e-219 687.0
CSH2_k127_3201681_3 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 299.0
CSH2_k127_3201681_4 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000001883 206.0
CSH2_k127_3201681_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000004643 193.0
CSH2_k127_3201681_6 PFAM GCN5-related N-acetyltransferase - - - 0.0000001732 60.0
CSH2_k127_3211489_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 353.0
CSH2_k127_3211489_2 transferase activity, transferring glycosyl groups K01179,K01356,K13735,K21449 - 3.2.1.4,3.4.21.88 0.00000003735 66.0
CSH2_k127_3211489_3 helix_turn_helix ASNC type K03719 - - 0.00001511 54.0
CSH2_k127_3211489_4 Uncharacterised protein - - - 0.0000187 56.0
CSH2_k127_3291732_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 399.0
CSH2_k127_3291732_1 PFAM proteinase inhibitor I4 serpin K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 296.0
CSH2_k127_3291732_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000001097 181.0
CSH2_k127_3291732_3 PFAM Thioredoxin K03671 - - 0.0000000000000000000007743 103.0
CSH2_k127_3291732_4 PFAM NHL repeat containing protein - - - 0.000000000000000009695 98.0
CSH2_k127_3291732_5 exo-alpha-(2->6)-sialidase activity - - - 0.00000003958 67.0
CSH2_k127_3426958_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.367e-211 689.0
CSH2_k127_3426958_1 tRNA binding K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 497.0
CSH2_k127_3426958_10 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.000000000002494 76.0
CSH2_k127_3426958_11 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000001712 72.0
CSH2_k127_3426958_12 Arsenic resistance protein ArsB K03325 - - 0.000002205 50.0
CSH2_k127_3426958_13 but it may be involved in stabilization of the trimeric complex - - - 0.000004884 52.0
CSH2_k127_3426958_14 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.00001629 48.0
CSH2_k127_3426958_15 Peptidase family C25 - - - 0.00001833 57.0
CSH2_k127_3426958_16 PFAM Sodium Bile acid symporter family K03325 - - 0.00003024 47.0
CSH2_k127_3426958_17 AsnC-type helix-turn-helix domain - - - 0.0008665 48.0
CSH2_k127_3426958_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 429.0
CSH2_k127_3426958_3 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 387.0
CSH2_k127_3426958_4 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 362.0
CSH2_k127_3426958_5 Helix-turn-helix XRE-family like proteins K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000007499 237.0
CSH2_k127_3426958_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000004777 207.0
CSH2_k127_3426958_7 Belongs to the peptidase S8 family K20276 - - 0.0000000000000000000000000005518 132.0
CSH2_k127_3426958_8 Belongs to the peptidase S8 family K14645 - - 0.00000000000000000001356 106.0
CSH2_k127_3426958_9 Sodium Bile acid symporter family K03325 - - 0.000000000000000002757 88.0
CSH2_k127_3441620_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 509.0
CSH2_k127_3441620_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 353.0
CSH2_k127_3441620_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000001282 205.0
CSH2_k127_3441620_3 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0000924 48.0
CSH2_k127_3465845_0 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 437.0
CSH2_k127_3465845_1 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 332.0
CSH2_k127_3465845_10 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000001708 168.0
CSH2_k127_3465845_11 PFAM thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000006644 143.0
CSH2_k127_3465845_12 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.0000000000000000000000000000000009238 135.0
CSH2_k127_3465845_13 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000001912 129.0
CSH2_k127_3465845_14 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000007542 136.0
CSH2_k127_3465845_15 Transcriptional regulator, TrmB - - - 0.00000000000000000000000001748 113.0
CSH2_k127_3465845_16 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000006271 118.0
CSH2_k127_3465845_17 Transcriptional regulator, AbrB family - - - 0.000000000000000004497 89.0
CSH2_k127_3465845_18 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000001569 78.0
CSH2_k127_3465845_19 Protein of unknown function (DUF998) - - - 0.0000000000003305 77.0
CSH2_k127_3465845_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000001222 245.0
CSH2_k127_3465845_20 - - - - 0.000000000000411 72.0
CSH2_k127_3465845_21 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000006322 82.0
CSH2_k127_3465845_22 peptidase activity, acting on L-amino acid peptides K01337,K13735,K20276 - 3.4.21.50 0.00000003779 68.0
CSH2_k127_3465845_23 TIGRFAM DNA polymerase (pol2) K02319 - 2.7.7.7 0.00008397 56.0
CSH2_k127_3465845_3 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001309 251.0
CSH2_k127_3465845_4 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000009558 230.0
CSH2_k127_3465845_5 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000000000000000000000000000002811 233.0
CSH2_k127_3465845_6 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000002807 220.0
CSH2_k127_3465845_7 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000121 237.0
CSH2_k127_3465845_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000001317 198.0
CSH2_k127_3465845_9 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000000002655 167.0
CSH2_k127_3528031_0 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 315.0
CSH2_k127_3528031_1 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 299.0
CSH2_k127_3528031_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001484 269.0
CSH2_k127_3528031_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001398 261.0
CSH2_k127_3528031_4 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000002322 74.0
CSH2_k127_3541182_0 COG2041 Sulfite oxidase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 290.0
CSH2_k127_3541182_1 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007216 261.0
CSH2_k127_3541182_10 Domain of unknown function (DUF4870) - - - 0.000000000000000000004393 96.0
CSH2_k127_3541182_11 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000008224 93.0
CSH2_k127_3541182_12 PKD domain K19668 - 3.2.1.91 0.0000000000000004459 93.0
CSH2_k127_3541182_13 Domain of unknown function (DUF4382) - - - 0.00000000001069 72.0
CSH2_k127_3541182_14 transferase activity, transferring glycosyl groups K01186,K01371,K20276 - 3.2.1.18,3.4.22.38 0.00000000006286 75.0
CSH2_k127_3541182_15 - - - - 0.00000005072 57.0
CSH2_k127_3541182_16 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000007835 66.0
CSH2_k127_3541182_17 EamA-like transporter family - - - 0.0001156 53.0
CSH2_k127_3541182_2 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006859 240.0
CSH2_k127_3541182_3 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000006996 229.0
CSH2_k127_3541182_4 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000005388 243.0
CSH2_k127_3541182_5 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000003363 177.0
CSH2_k127_3541182_6 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000009788 160.0
CSH2_k127_3541182_7 Protein of unknown function (DUF996) - - - 0.000000000000000000000000000000000000009824 152.0
CSH2_k127_3541182_8 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000006619 133.0
CSH2_k127_3541182_9 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000001262 110.0
CSH2_k127_3544199_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1131.0
CSH2_k127_3544199_1 Cell division protein 48 (CDC48) domain 2 K13525 - - 9.095e-277 875.0
CSH2_k127_3544199_10 - - - - 0.00002442 53.0
CSH2_k127_3544199_2 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 462.0
CSH2_k127_3544199_3 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000001247 215.0
CSH2_k127_3544199_4 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000000000000001809 220.0
CSH2_k127_3544199_5 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.00000000000000000000000000000000004244 137.0
CSH2_k127_3544199_6 TIGRFAM geranylgeranyl reductase family - - - 0.0000000000000000000000002378 108.0
CSH2_k127_3544199_7 PRC-barrel domain - - - 0.000000000000001906 79.0
CSH2_k127_3544199_8 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.0000000000001719 77.0
CSH2_k127_3544199_9 - - - - 0.00000002577 61.0
CSH2_k127_3632260_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000001974 251.0
CSH2_k127_3632260_1 - - - - 0.000233 51.0
CSH2_k127_3676475_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 7.826e-223 695.0
CSH2_k127_3676475_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000142 223.0
CSH2_k127_3676475_2 - - - - 0.0003578 51.0
CSH2_k127_3692218_0 COG1131 ABC-type multidrug transport system ATPase component K16907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 354.0
CSH2_k127_3692218_1 SMART zinc finger, CDGSH-type domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001256 254.0
CSH2_k127_3692218_10 Winged helix-turn-helix - - - 0.0000000000000000000000006435 106.0
CSH2_k127_3692218_11 - - - - 0.000000000000000001309 98.0
CSH2_k127_3692218_12 Glycosyl hydrolase family 53 K01224 - 3.2.1.89 0.0000000000000003404 91.0
CSH2_k127_3692218_13 Protein of unknown function (DUF3788) - - - 0.00000000000006905 77.0
CSH2_k127_3692218_14 - - - - 0.00000000001462 73.0
CSH2_k127_3692218_15 - - - - 0.0000000001263 71.0
CSH2_k127_3692218_16 Fibronectin type III domain protein K21571 - - 0.000000106 64.0
CSH2_k127_3692218_17 Thioredoxin K03671 - - 0.000000303 57.0
CSH2_k127_3692218_18 2TM domain - - - 0.0000006053 55.0
CSH2_k127_3692218_19 Belongs to the peptidase S8 family - - - 0.000001049 63.0
CSH2_k127_3692218_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004157 246.0
CSH2_k127_3692218_20 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0006299 53.0
CSH2_k127_3692218_3 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000005688 211.0
CSH2_k127_3692218_4 RibD C-terminal domain K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000000008949 193.0
CSH2_k127_3692218_5 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000005635 182.0
CSH2_k127_3692218_6 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000364 177.0
CSH2_k127_3692218_7 Bacterio-opsin activator HTH K06930,K06988 - 1.5.1.40 0.0000000000000000000000000000000000003327 149.0
CSH2_k127_3692218_8 - K16905,K16906 - - 0.0000000000000000000000000000248 128.0
CSH2_k127_3692218_9 transmembrane transport K01992 - - 0.000000000000000000000000001609 121.0
CSH2_k127_3764600_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 411.0
CSH2_k127_3764600_1 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.000000000000009105 83.0
CSH2_k127_3764600_2 PFAM Peptidase C1A, papain - - - 0.00000000000001484 86.0
CSH2_k127_3896698_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.661e-255 804.0
CSH2_k127_3896698_1 PFAM GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 450.0
CSH2_k127_3896698_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 321.0
CSH2_k127_3896698_3 TatD related DNase K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000002337 239.0
CSH2_k127_3896698_4 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000001322 214.0
CSH2_k127_3896698_5 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.000000000000000000000000000000000000000000000000002443 188.0
CSH2_k127_3896698_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000002318 158.0
CSH2_k127_3896698_7 Phosphoesterase PA-phosphatase - - - 0.00000000000000003325 91.0
CSH2_k127_3896698_8 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0002563 52.0
CSH2_k127_391098_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000001848 115.0
CSH2_k127_3913661_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 9.15e-303 951.0
CSH2_k127_3913661_1 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000004449 196.0
CSH2_k127_3913661_2 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000001071 142.0
CSH2_k127_3913661_3 parallel beta-helix repeat K03671 - - 0.000000000000001982 88.0
CSH2_k127_3913661_4 Peptidase family C25 - - - 0.000001589 61.0
CSH2_k127_3942251_0 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 8.525e-234 738.0
CSH2_k127_3942251_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 7.743e-220 695.0
CSH2_k127_3942251_10 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001368 257.0
CSH2_k127_3942251_11 Chlorophyllase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000002981 230.0
CSH2_k127_3942251_12 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000001008 213.0
CSH2_k127_3942251_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000009907 190.0
CSH2_k127_3942251_14 - - - - 0.0000000000000000000000000000000000000000000000000003177 194.0
CSH2_k127_3942251_15 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000397 191.0
CSH2_k127_3942251_16 ATP-binding region ATPase domain protein K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.00000000000000000000000000000000000000000000000001648 199.0
CSH2_k127_3942251_17 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000003375 189.0
CSH2_k127_3942251_18 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000002999 198.0
CSH2_k127_3942251_19 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000001441 183.0
CSH2_k127_3942251_2 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 477.0
CSH2_k127_3942251_20 Phosphate-binding protein PstS 2 K02040 - - 0.0000000000000000000000000000000000000000000002249 178.0
CSH2_k127_3942251_21 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000005881 166.0
CSH2_k127_3942251_22 transcriptional - - - 0.00000000000000000000000007655 110.0
CSH2_k127_3942251_23 PFAM regulatory protein, ArsR K03892,K21903 - - 0.0000000000000000004806 89.0
CSH2_k127_3942251_24 Domain of unknown function (DUF2341) - - - 0.000000000002559 81.0
CSH2_k127_3942251_25 extracellular matrix structural constituent - - - 0.00000000003644 75.0
CSH2_k127_3942251_26 pathogenesis K13669 - - 0.00000000007002 76.0
CSH2_k127_3942251_27 GDSL-like Lipase/Acylhydrolase family K06882 - - 0.00005138 57.0
CSH2_k127_3942251_3 Aconitase family (aconitate hydratase) K01703,K01705,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35,4.2.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 456.0
CSH2_k127_3942251_4 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 428.0
CSH2_k127_3942251_5 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 369.0
CSH2_k127_3942251_6 PhoU domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 364.0
CSH2_k127_3942251_7 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 362.0
CSH2_k127_3942251_8 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 334.0
CSH2_k127_3942251_9 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001403 269.0
CSH2_k127_4062220_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 491.0
CSH2_k127_4062220_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 478.0
CSH2_k127_4062220_10 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000000000000000000002131 160.0
CSH2_k127_4062220_11 transcriptional - - - 0.0000000000000000000000000001202 117.0
CSH2_k127_4062220_12 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000009612 115.0
CSH2_k127_4062220_13 Transcriptional regulator, TrmB - - - 0.0000000000000000000000003837 109.0
CSH2_k127_4062220_14 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000000000001907 101.0
CSH2_k127_4062220_15 - - - - 0.00000000003856 75.0
CSH2_k127_4062220_16 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000001436 65.0
CSH2_k127_4062220_17 Domain of unknown function (DUF4314) - - - 0.00000002245 57.0
CSH2_k127_4062220_18 Lrp/AsnC ligand binding domain - - - 0.00000008619 54.0
CSH2_k127_4062220_2 agmatine deiminase activity K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 482.0
CSH2_k127_4062220_3 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 394.0
CSH2_k127_4062220_4 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 353.0
CSH2_k127_4062220_5 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 331.0
CSH2_k127_4062220_6 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 318.0
CSH2_k127_4062220_7 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004627 252.0
CSH2_k127_4062220_8 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000259 241.0
CSH2_k127_4062220_9 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.000000000000000000000000000000000000000000000000000000003583 206.0
CSH2_k127_4100959_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.026e-196 623.0
CSH2_k127_4108588_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 552.0
CSH2_k127_4108588_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 467.0
CSH2_k127_4108588_10 - - - - 0.0000000000000000001814 92.0
CSH2_k127_4108588_11 COG0784 FOG CheY-like receiver - - - 0.0000000000007861 79.0
CSH2_k127_4108588_12 Pectate lyase - - - 0.000000001887 71.0
CSH2_k127_4108588_13 thymidylate synthase K00560 - 2.1.1.45 0.0000001494 57.0
CSH2_k127_4108588_2 COG1549 Queuine tRNA-ribosyltransferases, contain PUA domain K07557 - 2.6.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 340.0
CSH2_k127_4108588_3 PFAM Methionine synthase, vitamin-B12 independent K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000000000000000000000000000000000000004361 194.0
CSH2_k127_4108588_4 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000001862 181.0
CSH2_k127_4108588_5 Lysine methyltransferase K02493 - 2.1.1.297 0.00000000000000000000000000000000006515 143.0
CSH2_k127_4108588_6 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.00000000000000000000000000000000009284 139.0
CSH2_k127_4108588_7 - - - - 0.000000000000000000000000000001038 130.0
CSH2_k127_4108588_8 Peptidase family M50 - - - 0.0000000000000000000000000002516 123.0
CSH2_k127_4108588_9 OB-fold nucleic acid binding domain - - - 0.0000000000000000000000007804 116.0
CSH2_k127_4109489_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 435.0
CSH2_k127_4109489_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 400.0
CSH2_k127_4109489_2 Belongs to the peptidase S16 family K06870 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 313.0
CSH2_k127_4109489_3 calcium proton exchanger K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001703 286.0
CSH2_k127_4109489_4 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002927 235.0
CSH2_k127_4109489_5 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000006285 218.0
CSH2_k127_4109489_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000003982 199.0
CSH2_k127_4109489_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000001724 176.0
CSH2_k127_4109489_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000004225 133.0
CSH2_k127_4109489_9 Pectate lyase - - - 0.00003702 57.0
CSH2_k127_4259168_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1585.0
CSH2_k127_4259168_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 590.0
CSH2_k127_4259168_10 PFAM HD domain K03698 - - 0.0000000000000000000000000000000000000000000000000000000000007258 224.0
CSH2_k127_4259168_11 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.0000000000000000000000000000000000000000000000000007662 190.0
CSH2_k127_4259168_12 Belongs to the archaeal adenylate kinase family K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000001567 188.0
CSH2_k127_4259168_13 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000000000000000000003886 180.0
CSH2_k127_4259168_14 phosphoesterase RecJ domain protein - - - 0.0000000000000000000000000000000000000000000003671 179.0
CSH2_k127_4259168_15 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000009034 169.0
CSH2_k127_4259168_16 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000006631 139.0
CSH2_k127_4259168_17 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000008689 136.0
CSH2_k127_4259168_18 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000001874 127.0
CSH2_k127_4259168_19 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.000000000000000000000000004349 121.0
CSH2_k127_4259168_2 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 534.0
CSH2_k127_4259168_20 Integral membrane protein DUF106 - - - 0.000000000000000000000001781 111.0
CSH2_k127_4259168_21 binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000003391 103.0
CSH2_k127_4259168_22 Belongs to the UPF0434 family - - - 0.000000000000009713 76.0
CSH2_k127_4259168_3 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 447.0
CSH2_k127_4259168_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 381.0
CSH2_k127_4259168_5 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 369.0
CSH2_k127_4259168_6 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 369.0
CSH2_k127_4259168_7 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 366.0
CSH2_k127_4259168_8 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002368 227.0
CSH2_k127_4259168_9 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000009387 231.0
CSH2_k127_4275398_0 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 376.0
CSH2_k127_4275398_1 PD-(D/E)XK nuclease superfamily K07465 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 366.0
CSH2_k127_4275398_10 PFAM Peptidase C1A, papain - - - 0.000000000000000000000003077 120.0
CSH2_k127_4275398_11 Belongs to the peptidase S8 family - - - 0.0000000000000000000001974 111.0
CSH2_k127_4275398_12 thiolester hydrolase activity K01259,K06889,K21193 - 3.4.11.5 0.000000000000000000196 99.0
CSH2_k127_4275398_13 Psort location Cytoplasmic, score - - - 0.000000000000001616 86.0
CSH2_k127_4275398_14 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000003346 86.0
CSH2_k127_4275398_15 Nitroreductase family - - - 0.000000000006606 79.0
CSH2_k127_4275398_16 Pkd domain containing protein - - - 0.0000000002269 74.0
CSH2_k127_4275398_17 Peptidase family C25 - - - 0.000000003133 70.0
CSH2_k127_4275398_18 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.000000003932 70.0
CSH2_k127_4275398_19 PFAM Nitroreductase - - - 0.00000006306 66.0
CSH2_k127_4275398_2 Chitin synthase K00752 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0051704,GO:0071944,GO:0090605,GO:0090609 2.4.1.212 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 342.0
CSH2_k127_4275398_20 Rhomboid family - - - 0.000001108 61.0
CSH2_k127_4275398_21 EamA-like transporter family K08978 - - 0.00003515 55.0
CSH2_k127_4275398_22 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.0002596 52.0
CSH2_k127_4275398_23 bacterial-type flagellum-dependent cell motility - - - 0.0005151 52.0
CSH2_k127_4275398_3 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007388 279.0
CSH2_k127_4275398_4 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000002469 174.0
CSH2_k127_4275398_5 Methyl-transferase - - - 0.000000000000000000000000000000000000000001046 166.0
CSH2_k127_4275398_6 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000733 165.0
CSH2_k127_4275398_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000001297 147.0
CSH2_k127_4275398_8 Radical SAM domain protein - - - 0.0000000000000000000000000000000004705 144.0
CSH2_k127_4275398_9 Caspase domain - - - 0.0000000000000000000000000000001366 135.0
CSH2_k127_428995_0 KH, type 1, domain K07041 - - 1.571e-260 816.0
CSH2_k127_428995_1 pyridoxal phosphate-dependent acyltransferase K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 445.0
CSH2_k127_428995_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002805 286.0
CSH2_k127_428995_3 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006865 274.0
CSH2_k127_428995_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000207 241.0
CSH2_k127_428995_5 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000162 205.0
CSH2_k127_428995_6 cyclohydrolase - - - 0.000000000000000000005705 95.0
CSH2_k127_4309158_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001071 266.0
CSH2_k127_4309158_1 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000008305 227.0
CSH2_k127_4309158_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000002662 216.0
CSH2_k127_4309158_3 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000007171 129.0
CSH2_k127_4330702_0 ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues K01648 GO:0000166,GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003878,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006066,GO:0006082,GO:0006084,GO:0006085,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009893,GO:0009987,GO:0012505,GO:0015936,GO:0016020,GO:0016053,GO:0016125,GO:0016126,GO:0016192,GO:0016740,GO:0016746,GO:0016999,GO:0017076,GO:0017144,GO:0018130,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030141,GO:0030554,GO:0031323,GO:0031325,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032940,GO:0032991,GO:0033500,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0034774,GO:0035337,GO:0035383,GO:0035384,GO:0035578,GO:0035639,GO:0036094,GO:0036230,GO:0042119,GO:0042582,GO:0042592,GO:0042593,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046165,GO:0046390,GO:0046394,GO:0046483,GO:0046903,GO:0046912,GO:0046949,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0055086,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901568,GO:1901570,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653,GO:1904813 2.3.3.8 6.773e-253 794.0
CSH2_k127_4330702_1 ATP citrate synthase activity K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 540.0
CSH2_k127_4330702_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 317.0
CSH2_k127_4359499_0 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 325.0
CSH2_k127_4359499_1 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000004421 196.0
CSH2_k127_4359499_2 LVIVD repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000003006 207.0
CSH2_k127_4362484_0 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000004577 189.0
CSH2_k127_4362484_1 DsrE/DsrF-like family K04085 - - 0.0000000000000000000000000000004061 125.0
CSH2_k127_4362484_2 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000001673 91.0
CSH2_k127_4362484_3 4Fe-4S dicluster domain K11473 - - 0.000000000000342 81.0
CSH2_k127_4393661_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 409.0
CSH2_k127_4393661_1 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 406.0
CSH2_k127_4393661_10 S-layer homology domain - - - 0.00000000218 72.0
CSH2_k127_4393661_11 Biotin-protein ligase, N terminal - - - 0.0001148 54.0
CSH2_k127_4393661_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 327.0
CSH2_k127_4393661_3 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001009 288.0
CSH2_k127_4393661_4 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002276 280.0
CSH2_k127_4393661_5 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000209 235.0
CSH2_k127_4393661_6 COG1668 ABC-type Na efflux pump, permease component - - - 0.0000000000000000000000000001828 128.0
CSH2_k127_4393661_7 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000002704 95.0
CSH2_k127_4393661_8 PFAM PKD domain containing protein - - - 0.000000000000003752 87.0
CSH2_k127_4393661_9 PFAM PKD domain containing protein - - - 0.000000000000008998 89.0
CSH2_k127_4394744_0 Pfam:DUF650 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 475.0
CSH2_k127_4394744_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 370.0
CSH2_k127_4394744_10 Methyltransferase domain - - - 0.00000000000003937 80.0
CSH2_k127_4394744_11 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.00000026 66.0
CSH2_k127_4394744_12 AMP-binding enzyme C-terminal domain - - - 0.0000024 61.0
CSH2_k127_4394744_13 Fibronectin type 3 domain - - - 0.00001592 60.0
CSH2_k127_4394744_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006436 281.0
CSH2_k127_4394744_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000001152 220.0
CSH2_k127_4394744_4 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000001961 178.0
CSH2_k127_4394744_5 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.00000000000000000000000000000000000000001246 158.0
CSH2_k127_4394744_6 LVIVD repeat-containing protein - - - 0.000000000000000000000001046 124.0
CSH2_k127_4394744_7 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000004704 99.0
CSH2_k127_4394744_8 Belongs to the UPF0235 family K09131 - - 0.00000000000000000002618 94.0
CSH2_k127_4394744_9 TOPRIM - - - 0.000000000000000001251 91.0
CSH2_k127_4401033_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.735e-225 713.0
CSH2_k127_4401033_1 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 467.0
CSH2_k127_4401033_10 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000001325 130.0
CSH2_k127_4401033_11 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.0000000000000000000000000004576 117.0
CSH2_k127_4401033_12 Transposase IS200 like K07491 - - 0.000000000000000000000001992 109.0
CSH2_k127_4401033_13 Fic/DOC family - - - 0.0000000000000000000001426 109.0
CSH2_k127_4401033_14 Cold shock protein K03704 - - 0.0000000000000000007902 87.0
CSH2_k127_4401033_15 Protease prsW family - - - 0.000000000000000001753 94.0
CSH2_k127_4401033_16 Zn-ribbon containing protein K07163 - - 0.00000000000000003919 88.0
CSH2_k127_4401033_17 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.000000000000007758 76.0
CSH2_k127_4401033_18 outer membrane autotransporter barrel domain - - - 0.0000000001006 76.0
CSH2_k127_4401033_19 acid phosphatase activity K22390 - - 0.0000000004169 73.0
CSH2_k127_4401033_2 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 417.0
CSH2_k127_4401033_20 - - - - 0.000003529 51.0
CSH2_k127_4401033_21 - - - - 0.00005518 49.0
CSH2_k127_4401033_22 Lrp/AsnC ligand binding domain K03719 - - 0.00008203 51.0
CSH2_k127_4401033_23 Ig domain protein group 2 domain protein - - - 0.0002989 54.0
CSH2_k127_4401033_24 Domain of unknown function (DUF4430) - - - 0.0002994 52.0
CSH2_k127_4401033_3 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 372.0
CSH2_k127_4401033_4 GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 297.0
CSH2_k127_4401033_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000000000000002351 251.0
CSH2_k127_4401033_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000004424 209.0
CSH2_k127_4401033_7 - - - - 0.000000000000000000000000000000000000000000000000000005511 197.0
CSH2_k127_4401033_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000000001567 160.0
CSH2_k127_4401033_9 PFAM PEGA domain - - - 0.00000000000000000000000000000000000003898 161.0
CSH2_k127_4411328_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 7.303e-213 706.0
CSH2_k127_4411328_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 463.0
CSH2_k127_4411328_10 ASNC family K03718 - - 0.000000000001429 73.0
CSH2_k127_4411328_11 Parallel beta-helix repeats - - - 0.000000000006399 79.0
CSH2_k127_4411328_12 Cobalamin biosynthesis protein CobT VWA domain - - - 0.0000005435 63.0
CSH2_k127_4411328_2 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 302.0
CSH2_k127_4411328_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002071 260.0
CSH2_k127_4411328_4 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000002202 175.0
CSH2_k127_4411328_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000001533 159.0
CSH2_k127_4411328_6 hydroxylase K15746 - 1.14.15.24 0.00000000000000000000000000000000001148 140.0
CSH2_k127_4411328_7 Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000000000000000002928 141.0
CSH2_k127_4411328_8 chitinase K01183 - 3.2.1.14 0.000000000000004743 89.0
CSH2_k127_4411328_9 helix_turn_helix ASNC type K03718 - - 0.0000000000001296 76.0
CSH2_k127_4415733_0 Psort location Cytoplasmic, score - - - 0.0 1422.0
CSH2_k127_4415733_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.515e-212 678.0
CSH2_k127_4415733_10 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000001479 223.0
CSH2_k127_4415733_11 heterodisulfide reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000004477 216.0
CSH2_k127_4415733_12 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000005204 218.0
CSH2_k127_4415733_13 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000004107 184.0
CSH2_k127_4415733_14 hydrogenase maturation protease K03605 - - 0.000000000000000000000005183 108.0
CSH2_k127_4415733_15 4Fe-4S dicluster domain K03390,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000002068 102.0
CSH2_k127_4415733_16 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000001054 87.0
CSH2_k127_4415733_17 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000008237 80.0
CSH2_k127_4415733_18 PFAM Methyltransferase type 11 - - - 0.000000000006591 74.0
CSH2_k127_4415733_19 Transglutaminase/protease-like homologues - - - 0.0000000006978 70.0
CSH2_k127_4415733_2 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.03e-211 670.0
CSH2_k127_4415733_20 Bacterial transferase hexapeptide - - - 0.000000006364 66.0
CSH2_k127_4415733_21 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00004167 49.0
CSH2_k127_4415733_22 PFAM transglutaminase domain protein - - - 0.0007709 51.0
CSH2_k127_4415733_3 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 613.0
CSH2_k127_4415733_4 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 557.0
CSH2_k127_4415733_5 Nickel-dependent hydrogenase K00436,K14126 - 1.12.1.2,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 485.0
CSH2_k127_4415733_6 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 463.0
CSH2_k127_4415733_7 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002321 278.0
CSH2_k127_4415733_8 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005442 262.0
CSH2_k127_4415733_9 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00125 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000005322 266.0
CSH2_k127_445559_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 407.0
CSH2_k127_4548325_0 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000298 196.0
CSH2_k127_4548325_1 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000004861 171.0
CSH2_k127_4548325_2 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000005704 153.0
CSH2_k127_4548325_3 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000002602 111.0
CSH2_k127_4548325_4 serine threonine protein kinase - - - 0.00000000000000000000007324 106.0
CSH2_k127_4548325_5 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.0000000000000005238 85.0
CSH2_k127_4548325_6 - - - - 0.0000000000000007428 84.0
CSH2_k127_4548325_7 Periplasmic binding protein K02016 - - 0.0000000001567 70.0
CSH2_k127_4548325_8 fosmidomycin resistance protein K08223 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000001439 70.0
CSH2_k127_4548325_9 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000001176 56.0
CSH2_k127_4580070_0 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.000000000000000000000000000000000002473 141.0
CSH2_k127_4580070_1 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000001129 122.0
CSH2_k127_4580070_2 TIGRFAM geranylgeranyl reductase family - - - 0.0000000000000000000000000008708 116.0
CSH2_k127_4580070_3 - - - - 0.00000002056 62.0
CSH2_k127_4586762_0 COG0058 Glucan phosphorylase - - - 1.887e-224 708.0
CSH2_k127_4586762_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 494.0
CSH2_k127_4586762_10 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 294.0
CSH2_k127_4586762_11 COG1691 NCAIR mutase (PurE)-related K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 290.0
CSH2_k127_4586762_12 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000723 288.0
CSH2_k127_4586762_13 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002113 266.0
CSH2_k127_4586762_14 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000321 265.0
CSH2_k127_4586762_15 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003856 258.0
CSH2_k127_4586762_16 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000124 248.0
CSH2_k127_4586762_17 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000000000000000001957 252.0
CSH2_k127_4586762_18 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000001278 258.0
CSH2_k127_4586762_19 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000009748 239.0
CSH2_k127_4586762_2 peptidyl-lysine modification to peptidyl-hypusine K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 465.0
CSH2_k127_4586762_20 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000006286 224.0
CSH2_k127_4586762_21 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000001404 215.0
CSH2_k127_4586762_22 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000000000000000000003974 204.0
CSH2_k127_4586762_23 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000002991 199.0
CSH2_k127_4586762_24 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000006131 195.0
CSH2_k127_4586762_25 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000000000000000000000000000000000000000000462 191.0
CSH2_k127_4586762_26 RNA-binding protein of the translin family K07477 - - 0.000000000000000000000000000000000000003981 155.0
CSH2_k127_4586762_27 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000000001881 153.0
CSH2_k127_4586762_28 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000000000000000000823 143.0
CSH2_k127_4586762_29 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00000000000000000000000000000000455 132.0
CSH2_k127_4586762_3 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 467.0
CSH2_k127_4586762_30 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000004797 126.0
CSH2_k127_4586762_31 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000004614 101.0
CSH2_k127_4586762_32 PFAM Peptidase C1A, papain - - - 0.0000000000000000767 95.0
CSH2_k127_4586762_33 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000001243 91.0
CSH2_k127_4586762_34 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000005352 84.0
CSH2_k127_4586762_35 cluster protein-associated redox disulfide domain - - - 0.00000000000004272 76.0
CSH2_k127_4586762_36 Archaeal Type IV pilin, N-terminal - - - 0.000000000002501 80.0
CSH2_k127_4586762_37 helix_turn_helix ASNC type - - - 0.00000001655 66.0
CSH2_k127_4586762_38 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000001735 54.0
CSH2_k127_4586762_39 - - - - 0.00003552 53.0
CSH2_k127_4586762_4 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 456.0
CSH2_k127_4586762_40 acid phosphatase activity - - - 0.00006824 55.0
CSH2_k127_4586762_41 parallel beta-helix repeat K03671 - - 0.0001461 47.0
CSH2_k127_4586762_42 helix_turn_helix ASNC type K03719 - - 0.0001824 51.0
CSH2_k127_4586762_5 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 432.0
CSH2_k127_4586762_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 373.0
CSH2_k127_4586762_7 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 349.0
CSH2_k127_4586762_8 Clp protease K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 337.0
CSH2_k127_4586762_9 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 316.0
CSH2_k127_4603440_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000003942 254.0
CSH2_k127_4603440_1 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000001561 168.0
CSH2_k127_4603440_2 Peptidase family C25 - - - 0.000001093 61.0
CSH2_k127_4658928_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 3.508e-312 970.0
CSH2_k127_4658928_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.193e-272 852.0
CSH2_k127_4658928_10 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 412.0
CSH2_k127_4658928_11 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 382.0
CSH2_k127_4658928_12 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 363.0
CSH2_k127_4658928_13 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 366.0
CSH2_k127_4658928_14 TIGRFAM ribosomal RNA small subunit methyltransferase RsmB K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 365.0
CSH2_k127_4658928_15 Glycogen debranching enzyme N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 368.0
CSH2_k127_4658928_16 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 342.0
CSH2_k127_4658928_17 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 337.0
CSH2_k127_4658928_18 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 321.0
CSH2_k127_4658928_19 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 315.0
CSH2_k127_4658928_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 598.0
CSH2_k127_4658928_20 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 320.0
CSH2_k127_4658928_21 Starch synthase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 317.0
CSH2_k127_4658928_22 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 306.0
CSH2_k127_4658928_23 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 303.0
CSH2_k127_4658928_24 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 301.0
CSH2_k127_4658928_25 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 299.0
CSH2_k127_4658928_26 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001804 288.0
CSH2_k127_4658928_27 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000267 283.0
CSH2_k127_4658928_28 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003134 295.0
CSH2_k127_4658928_29 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000113 273.0
CSH2_k127_4658928_3 PFAM multi antimicrobial extrusion protein MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 487.0
CSH2_k127_4658928_30 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001198 269.0
CSH2_k127_4658928_31 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002791 272.0
CSH2_k127_4658928_32 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000006713 270.0
CSH2_k127_4658928_33 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000006579 258.0
CSH2_k127_4658928_34 Belongs to the phosphohexose mutase family K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000007988 269.0
CSH2_k127_4658928_35 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006209 266.0
CSH2_k127_4658928_36 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003515 228.0
CSH2_k127_4658928_37 Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000003373 221.0
CSH2_k127_4658928_38 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000001193 208.0
CSH2_k127_4658928_39 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000001308 213.0
CSH2_k127_4658928_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 480.0
CSH2_k127_4658928_40 PFAM transferase hexapeptide repeat containing protein K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000004412 218.0
CSH2_k127_4658928_41 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000000000009043 207.0
CSH2_k127_4658928_42 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000007518 197.0
CSH2_k127_4658928_43 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000004791 181.0
CSH2_k127_4658928_44 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000000000000000000002113 185.0
CSH2_k127_4658928_45 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000001749 176.0
CSH2_k127_4658928_46 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000009361 178.0
CSH2_k127_4658928_47 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000007161 171.0
CSH2_k127_4658928_48 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000007812 164.0
CSH2_k127_4658928_49 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000001057 156.0
CSH2_k127_4658928_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 470.0
CSH2_k127_4658928_50 SMART Excinuclease ABC, C subunit - - - 0.0000000000000000000000000000000000003337 144.0
CSH2_k127_4658928_51 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000009116 101.0
CSH2_k127_4658928_52 Lrp/AsnC ligand binding domain - - - 0.0000000000000000002129 90.0
CSH2_k127_4658928_53 PFAM regulatory protein, ArsR - - - 0.0000000000000000002645 96.0
CSH2_k127_4658928_54 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000006966 91.0
CSH2_k127_4658928_55 Glutaredoxin - - - 0.000000000000000002422 88.0
CSH2_k127_4658928_56 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000008269 93.0
CSH2_k127_4658928_57 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives - - - 0.00000000000000002315 86.0
CSH2_k127_4658928_58 Vacuolar protein sorting-associated protein 62 - GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005783,GO:0006605,GO:0006623,GO:0006810,GO:0006886,GO:0007034,GO:0008104,GO:0008150,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0031090,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072665,GO:0072666,GO:0098588,GO:0098805,GO:0098852 - 0.0000000000000006889 91.0
CSH2_k127_4658928_59 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000001395 78.0
CSH2_k127_4658928_6 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 466.0
CSH2_k127_4658928_60 Domain of unknown function (DUF1610) K07580 - - 0.000000000000002689 76.0
CSH2_k127_4658928_61 sequence-specific DNA binding K07108 - - 0.00000000000003244 76.0
CSH2_k127_4658928_62 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000003038 72.0
CSH2_k127_4658928_63 - - - - 0.00000000001009 78.0
CSH2_k127_4658928_64 Caspase domain - - - 0.0000006366 60.0
CSH2_k127_4658928_65 PFAM PKD domain containing protein - - - 0.00000346 60.0
CSH2_k127_4658928_66 - - - - 0.000008338 49.0
CSH2_k127_4658928_67 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00003737 50.0
CSH2_k127_4658928_68 hemerythrin HHE cation binding domain - - - 0.0005558 48.0
CSH2_k127_4658928_7 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 454.0
CSH2_k127_4658928_8 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 432.0
CSH2_k127_4658928_9 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 422.0
CSH2_k127_4881308_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 426.0
CSH2_k127_4881308_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 380.0
CSH2_k127_4881308_2 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 344.0
CSH2_k127_4881308_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000004826 59.0
CSH2_k127_4974393_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 540.0
CSH2_k127_4974393_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K03918 - 2.6.1.19,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 531.0
CSH2_k127_4974393_10 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000236 276.0
CSH2_k127_4974393_11 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000953 275.0
CSH2_k127_4974393_12 GHMP kinases C terminal K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000007321 262.0
CSH2_k127_4974393_13 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000009049 253.0
CSH2_k127_4974393_14 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000009097 228.0
CSH2_k127_4974393_15 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000003254 186.0
CSH2_k127_4974393_16 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.00000000000000000000000000000000000000000000000000749 193.0
CSH2_k127_4974393_17 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.00000000000000000000000000000000000000000003312 173.0
CSH2_k127_4974393_18 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000004844 149.0
CSH2_k127_4974393_19 radical SAM domain protein K07011,K22227 - - 0.0000000000000000000000000000000005986 138.0
CSH2_k127_4974393_2 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 503.0
CSH2_k127_4974393_20 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000000000009598 129.0
CSH2_k127_4974393_21 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000004026 121.0
CSH2_k127_4974393_22 TIGRFAM mutator mutT protein K03574 - 3.6.1.55 0.00000000000000000000000005787 111.0
CSH2_k127_4974393_24 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000007072 76.0
CSH2_k127_4974393_25 secreted hydrolase - - - 0.0000001016 64.0
CSH2_k127_4974393_26 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000003781 61.0
CSH2_k127_4974393_3 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 496.0
CSH2_k127_4974393_4 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 467.0
CSH2_k127_4974393_5 PFAM Citrate lyase, alpha subunit K01643 - 2.8.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 466.0
CSH2_k127_4974393_6 resolution of meiotic recombination intermediates - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 463.0
CSH2_k127_4974393_7 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 343.0
CSH2_k127_4974393_8 TIGRFAM UbiD family decarboxylase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 299.0
CSH2_k127_4974393_9 tRNA pseudouridine synthase D K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009151 285.0
CSH2_k127_5039766_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 556.0
CSH2_k127_5039766_1 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000000000000000000000000000000000000682 205.0
CSH2_k127_5039766_2 Peptidase family M50 - - - 0.00000000000000000000000000001974 120.0
CSH2_k127_5039766_3 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000004793 114.0
CSH2_k127_5039766_4 - - - - 0.00000000000000004049 83.0
CSH2_k127_5039766_5 - - - - 0.000000000000008397 83.0
CSH2_k127_5039766_6 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000002491 70.0
CSH2_k127_5063165_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 5.344e-243 781.0
CSH2_k127_5063165_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 618.0
CSH2_k127_5063165_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 604.0
CSH2_k127_5063165_3 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 347.0
CSH2_k127_5063165_4 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000001463 203.0
CSH2_k127_5063165_5 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000008986 57.0
CSH2_k127_5108767_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 417.0
CSH2_k127_5110084_0 Flavin containing amine oxidoreductase K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 591.0
CSH2_k127_5110084_1 PFAM DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 533.0
CSH2_k127_5110084_10 lycopene cyclase - - - 0.00000000000000000000000000000000000000000000000000001748 196.0
CSH2_k127_5110084_11 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000002157 191.0
CSH2_k127_5110084_12 Histidine kinase - - - 0.0000000000000000000000000000000000000000001343 168.0
CSH2_k127_5110084_13 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000002105 117.0
CSH2_k127_5110084_14 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000006841 110.0
CSH2_k127_5110084_15 Predicted membrane protein (DUF2318) - - - 0.00000000000000000000004004 104.0
CSH2_k127_5110084_16 - - - - 0.000000000000000000001162 102.0
CSH2_k127_5110084_17 sequence-specific DNA binding K07108 - - 0.0000000000000871 75.0
CSH2_k127_5110084_19 protein contain chitin-binding domain type 3 K21606 - 3.2.1.202 0.000006588 59.0
CSH2_k127_5110084_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 386.0
CSH2_k127_5110084_20 membrane - - - 0.0002695 50.0
CSH2_k127_5110084_3 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 368.0
CSH2_k127_5110084_4 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 346.0
CSH2_k127_5110084_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001808 275.0
CSH2_k127_5110084_6 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001454 281.0
CSH2_k127_5110084_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000177 267.0
CSH2_k127_5110084_8 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004492 267.0
CSH2_k127_5110084_9 Co Zn Cd efflux system component K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000001441 232.0
CSH2_k127_5128732_0 asparaginyl-tRNA aminoacylation K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 430.0
CSH2_k127_5128732_1 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004885 233.0
CSH2_k127_5128732_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000002062 182.0
CSH2_k127_5128732_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000004115 160.0
CSH2_k127_5128732_4 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000001212 100.0
CSH2_k127_5128732_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000002948 103.0
CSH2_k127_5128732_6 PKD domain - - - 0.000000003251 69.0
CSH2_k127_5128732_7 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000002649 64.0
CSH2_k127_5137712_0 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 357.0
CSH2_k127_5137712_1 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000000000002496 241.0
CSH2_k127_5137712_2 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.00000000000000000000000000000000000000000000000001011 200.0
CSH2_k127_5137712_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000001217 102.0
CSH2_k127_5137712_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000001447 61.0
CSH2_k127_5137712_5 SCP-2 sterol transfer family - - - 0.0003772 48.0
CSH2_k127_5150192_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1300.0
CSH2_k127_5150192_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.785e-300 931.0
CSH2_k127_5150192_10 PFAM helix-turn-helix HxlR type - - - 0.000000000000000000000000000000000000002258 149.0
CSH2_k127_5150192_11 - - - - 0.0000000000000000000000000000000001834 140.0
CSH2_k127_5150192_2 Major facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 437.0
CSH2_k127_5150192_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 333.0
CSH2_k127_5150192_4 transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 304.0
CSH2_k127_5150192_5 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005733 272.0
CSH2_k127_5150192_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000001262 254.0
CSH2_k127_5150192_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000002236 231.0
CSH2_k127_5150192_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000005584 228.0
CSH2_k127_5150192_9 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000005206 218.0
CSH2_k127_5152193_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 379.0
CSH2_k127_5152193_1 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 379.0
CSH2_k127_5152193_2 Asparaginase, N-terminal K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000003476 232.0
CSH2_k127_5152193_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000001265 124.0
CSH2_k127_5152193_4 PKD domain containing protein - - - 0.00000000000001092 88.0
CSH2_k127_5152193_5 SpoVT / AbrB like domain - - - 0.0000000004272 63.0
CSH2_k127_5162558_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000365 263.0
CSH2_k127_5162558_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000001208 225.0
CSH2_k127_5162558_2 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.000000000000000834 81.0
CSH2_k127_5249025_0 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000000001672 157.0
CSH2_k127_5249025_1 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000004456 143.0
CSH2_k127_5249025_2 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000281 133.0
CSH2_k127_5257433_0 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 509.0
CSH2_k127_5257433_1 phenylalanine-tRNA ligase activity K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 501.0
CSH2_k127_5257433_10 Protein of unknown function (DUF1614) - - - 0.000000000000000000003478 103.0
CSH2_k127_5257433_11 Helix-turn-helix XRE-family like proteins K03627 - - 0.0000000000000000009833 93.0
CSH2_k127_5257433_13 antibiotic catabolic process K01406,K02414,K07004,K13277,K21449 - 3.4.24.40 0.00001262 59.0
CSH2_k127_5257433_14 COG1522 Transcriptional regulators - - - 0.00001687 55.0
CSH2_k127_5257433_15 S-layer homology domain - - - 0.00007371 54.0
CSH2_k127_5257433_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 484.0
CSH2_k127_5257433_3 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000006736 261.0
CSH2_k127_5257433_4 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000003763 198.0
CSH2_k127_5257433_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000002276 165.0
CSH2_k127_5257433_6 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000001565 154.0
CSH2_k127_5257433_7 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000002829 144.0
CSH2_k127_5257433_8 Family of unknown function (DUF438) K09155 - - 0.00000000000000000000000000008979 121.0
CSH2_k127_5257433_9 archaeal coiled-coil protein - - - 0.000000000000000000000004556 113.0
CSH2_k127_5289531_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1182.0
CSH2_k127_5289531_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 - 2.7.7.6 0.0 1165.0
CSH2_k127_5289531_10 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003773 258.0
CSH2_k127_5289531_11 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001389 245.0
CSH2_k127_5289531_12 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000001422 228.0
CSH2_k127_5289531_13 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000005677 211.0
CSH2_k127_5289531_14 OsmC-like protein K09136 - - 0.000000000000000000000000000000000000007573 149.0
CSH2_k127_5289531_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000001016 146.0
CSH2_k127_5289531_16 Participates in transcription termination K02600 - - 0.000000000000000000000000000006721 123.0
CSH2_k127_5289531_17 binds to the 23S rRNA K02921 - - 0.0000000000000000000000002981 108.0
CSH2_k127_5289531_18 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000004475 100.0
CSH2_k127_5289531_19 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000183 97.0
CSH2_k127_5289531_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 477.0
CSH2_k127_5289531_20 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.0000000000000001436 82.0
CSH2_k127_5289531_21 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000009192 57.0
CSH2_k127_5289531_22 Transcription factor Pcc1 K09741 - - 0.000001851 52.0
CSH2_k127_5289531_3 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 477.0
CSH2_k127_5289531_4 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 409.0
CSH2_k127_5289531_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 403.0
CSH2_k127_5289531_6 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 351.0
CSH2_k127_5289531_7 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 306.0
CSH2_k127_5289531_8 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 301.0
CSH2_k127_5289531_9 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004042 277.0
CSH2_k127_5305127_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 5.188e-315 980.0
CSH2_k127_5305127_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.474e-214 684.0
CSH2_k127_5305127_10 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000163 238.0
CSH2_k127_5305127_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003291 235.0
CSH2_k127_5305127_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001758 226.0
CSH2_k127_5305127_13 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000006468 218.0
CSH2_k127_5305127_14 HTH-type transcriptional regulatory protein K07728 - - 0.000000000000000000000000000000000000000000000000000000000000008073 227.0
CSH2_k127_5305127_15 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000002763 203.0
CSH2_k127_5305127_16 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000004101 186.0
CSH2_k127_5305127_17 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000002537 126.0
CSH2_k127_5305127_18 Peptidase family M28 - - - 0.0000000000000000000000000000001148 141.0
CSH2_k127_5305127_19 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.000000000000000000000000000007594 121.0
CSH2_k127_5305127_2 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 566.0
CSH2_k127_5305127_20 - - - - 0.0000000000000000000000002457 106.0
CSH2_k127_5305127_21 secreted hydrolase - - - 0.00000000000000003784 93.0
CSH2_k127_5305127_22 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.00000000000001197 79.0
CSH2_k127_5305127_23 bacterial-type flagellum-dependent cell motility - - - 0.00000000001537 78.0
CSH2_k127_5305127_24 - - - - 0.0000001239 57.0
CSH2_k127_5305127_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 544.0
CSH2_k127_5305127_4 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 547.0
CSH2_k127_5305127_5 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 425.0
CSH2_k127_5305127_6 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 405.0
CSH2_k127_5305127_7 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001224 273.0
CSH2_k127_5305127_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002722 271.0
CSH2_k127_5305127_9 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003049 266.0
CSH2_k127_5348408_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.989e-267 853.0
CSH2_k127_5348408_1 Aromatic amino acid lyase K01745 - 4.3.1.3 7.673e-263 817.0
CSH2_k127_5348408_10 Glycerate kinase K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 332.0
CSH2_k127_5348408_11 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 297.0
CSH2_k127_5348408_12 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002668 258.0
CSH2_k127_5348408_13 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000001045 242.0
CSH2_k127_5348408_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000137 225.0
CSH2_k127_5348408_15 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000005741 217.0
CSH2_k127_5348408_16 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000000000000000000000000000004101 203.0
CSH2_k127_5348408_17 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000009164 147.0
CSH2_k127_5348408_18 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000308 135.0
CSH2_k127_5348408_19 Peptidase family M28 - - - 0.0000000000000000000000003293 120.0
CSH2_k127_5348408_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 2.215e-225 711.0
CSH2_k127_5348408_20 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000004102 106.0
CSH2_k127_5348408_21 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000005337 96.0
CSH2_k127_5348408_22 snRNP Sm proteins K04796 - - 0.000000000000000007554 85.0
CSH2_k127_5348408_23 PFAM Peptidase C1A, papain - - - 0.00000000000000002525 95.0
CSH2_k127_5348408_25 PQQ enzyme repeat - - - 0.000000000003011 81.0
CSH2_k127_5348408_26 Periplasmic copper-binding protein (NosD) - - - 0.00000000001827 78.0
CSH2_k127_5348408_27 Propeptide_C25 - - - 0.00000000005262 75.0
CSH2_k127_5348408_28 oxidoreductase activity K07114,K12511 - - 0.0000000695 64.0
CSH2_k127_5348408_29 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000695 64.0
CSH2_k127_5348408_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 478.0
CSH2_k127_5348408_30 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000001292 65.0
CSH2_k127_5348408_4 Radical SAM domain protein K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 471.0
CSH2_k127_5348408_5 TIGRFAM Small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 399.0
CSH2_k127_5348408_6 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 377.0
CSH2_k127_5348408_7 glutamine synthetase K01915 GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 344.0
CSH2_k127_5348408_8 conserved protein related to pyruvate formate-lyase activating enzyme K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 338.0
CSH2_k127_5348408_9 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 334.0
CSH2_k127_5631985_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 2.807e-196 622.0
CSH2_k127_5631985_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 486.0
CSH2_k127_5631985_10 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000008811 174.0
CSH2_k127_5631985_11 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000009917 172.0
CSH2_k127_5631985_12 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000002854 158.0
CSH2_k127_5631985_13 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.000000000000000000000000000000000000003816 160.0
CSH2_k127_5631985_14 4Fe-4S binding domain protein - - - 0.000000000000000000000000000000000000007143 156.0
CSH2_k127_5631985_15 Uncharacterised protein family (UPF0179) K09730 - - 0.0000000000000000000000000000000001689 137.0
CSH2_k127_5631985_16 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000005282 147.0
CSH2_k127_5631985_17 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.00000000000000000000000000000001797 139.0
CSH2_k127_5631985_18 - - - - 0.000000000000000000000001196 108.0
CSH2_k127_5631985_19 membrane - - - 0.000000000000000000000004487 115.0
CSH2_k127_5631985_2 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 444.0
CSH2_k127_5631985_20 Thioredoxin-like - - - 0.000000000004147 73.0
CSH2_k127_5631985_3 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 355.0
CSH2_k127_5631985_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 351.0
CSH2_k127_5631985_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 302.0
CSH2_k127_5631985_6 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 310.0
CSH2_k127_5631985_7 HhH-GPD family K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000002489 241.0
CSH2_k127_5631985_8 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000005479 221.0
CSH2_k127_5631985_9 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000005852 186.0
CSH2_k127_572744_0 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 349.0
CSH2_k127_572744_1 PHP-associated - - - 0.00000000000000000000000000000003969 134.0
CSH2_k127_5733662_0 type II secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 573.0
CSH2_k127_5733662_1 PFAM Type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 540.0
CSH2_k127_5733662_2 PFAM Type II secretion system F domain K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001328 293.0
CSH2_k127_5733662_3 SMART AAA ATPase K07331 - - 0.0000000000000000000000000000000000000007402 156.0
CSH2_k127_5733662_4 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000000000000000004702 140.0
CSH2_k127_5733662_5 flagella protein K07327,K07328 - - 0.0000000000000000000007711 105.0
CSH2_k127_5733662_6 Archaebacterial flagellin K07330 - - 0.00000000000000000133 91.0
CSH2_k127_5733662_7 Archaeal flagellar protein F K07329 - - 0.0000000005677 65.0
CSH2_k127_5913389_0 serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000007348 210.0
CSH2_k127_5913389_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000002763 203.0
CSH2_k127_5913389_2 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000000000009633 188.0
CSH2_k127_5913389_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.0000000000000000000000000000000000000000000004819 173.0
CSH2_k127_5913389_4 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000388 125.0
CSH2_k127_5913389_5 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000001052 64.0
CSH2_k127_6010276_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 7.012e-245 777.0
CSH2_k127_6010276_1 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 2.232e-214 678.0
CSH2_k127_6010276_10 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 310.0
CSH2_k127_6010276_11 Alpha-amylase domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 295.0
CSH2_k127_6010276_12 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000176 284.0
CSH2_k127_6010276_13 Rad51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002898 243.0
CSH2_k127_6010276_14 metal ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000008589 228.0
CSH2_k127_6010276_15 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.00000000000000000000000000000000000000000000000000000000004499 214.0
CSH2_k127_6010276_16 Pfam:KaiC - - - 0.00000000000000000000000000000006644 135.0
CSH2_k127_6010276_17 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000005872 138.0
CSH2_k127_6010276_18 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000000003786 122.0
CSH2_k127_6010276_19 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000001008 102.0
CSH2_k127_6010276_2 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 440.0
CSH2_k127_6010276_20 Belongs to the glycosyl hydrolase 43 family K01278,K03561,K12287 - 3.4.14.5 0.00000000000000000003642 102.0
CSH2_k127_6010276_21 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000005147 95.0
CSH2_k127_6010276_22 - - - - 0.00000000000000006615 83.0
CSH2_k127_6010276_23 - - - - 0.000000000000004932 81.0
CSH2_k127_6010276_24 - - - - 0.00000000000001197 79.0
CSH2_k127_6010276_25 lactoylglutathione lyase activity - - - 0.0000000001077 69.0
CSH2_k127_6010276_26 Uncharacterised protein family UPF0058 - - - 0.0000001262 57.0
CSH2_k127_6010276_27 Peptidase family C25 - - - 0.000007113 59.0
CSH2_k127_6010276_28 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00001363 54.0
CSH2_k127_6010276_3 DNA primase K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 414.0
CSH2_k127_6010276_4 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 415.0
CSH2_k127_6010276_5 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 362.0
CSH2_k127_6010276_6 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 359.0
CSH2_k127_6010276_7 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 340.0
CSH2_k127_6010276_8 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 312.0
CSH2_k127_6010276_9 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 307.0
CSH2_k127_6011051_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 546.0
CSH2_k127_6011051_1 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000001754 213.0
CSH2_k127_6011051_2 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000000001677 171.0
CSH2_k127_6011051_3 Belongs to the UPF0218 family K09735 - - 0.000000000000000000000000001323 119.0
CSH2_k127_6011051_4 structural constituent of ribosome K02974 - - 0.0000000000000000000000993 101.0
CSH2_k127_6011051_5 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000001429 83.0
CSH2_k127_6011051_6 proteins of PilT N-term. Vapc superfamily K07158 - - 0.00000000000003762 77.0
CSH2_k127_6011051_7 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000001855 71.0
CSH2_k127_6038450_0 coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 467.0
CSH2_k127_6038450_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 350.0
CSH2_k127_6038450_2 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001043 259.0
CSH2_k127_6038450_3 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000471 172.0
CSH2_k127_6038450_4 heme transporter activity K08220 GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015232,GO:0015886,GO:0016020,GO:0020037,GO:0022857,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:1901363,GO:1901678 - 0.00000000007836 74.0
CSH2_k127_6038450_5 - - - - 0.00001073 53.0
CSH2_k127_6057776_0 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 308.0
CSH2_k127_6057776_1 addiction module toxin, RelE StbE family - - - 0.000000000000000000000000000001369 123.0
CSH2_k127_6057776_2 Glycogen recognition site of AMP-activated protein kinase K01442 - 3.5.1.24 0.000000000000000000000000003255 125.0
CSH2_k127_6057776_3 Protein of unknown function (DUF2683) - - - 0.00000000000000000000004305 101.0
CSH2_k127_6057776_4 - - - - 0.000000000000000000255 90.0
CSH2_k127_6057776_5 Belongs to the UPF0758 family K03630 - - 0.000000002177 59.0
CSH2_k127_6057776_6 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000002676 62.0
CSH2_k127_6057776_7 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000003421 62.0
CSH2_k127_6114786_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 507.0
CSH2_k127_6114786_1 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 463.0
CSH2_k127_6114786_10 - K07092 - - 0.00000000000000000000000000000000000000000000007008 171.0
CSH2_k127_6114786_11 Rubrerythrin - - - 0.0000000000000000000000000000000000003131 147.0
CSH2_k127_6114786_12 redox protein regulator of disulfide bond formation - - - 0.00000000000000000000000000000001251 128.0
CSH2_k127_6114786_13 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000676 132.0
CSH2_k127_6114786_14 Belongs to the Fur family K09825 - - 0.000000000000000000000000001247 117.0
CSH2_k127_6114786_15 protein conserved in archaea - - - 0.00000000000000000005605 93.0
CSH2_k127_6114786_17 - K03741 - 1.20.4.1 0.0000000000008754 74.0
CSH2_k127_6114786_18 hydrogenase expression formation protein HypD K04654 - - 0.000000000001872 67.0
CSH2_k127_6114786_19 PKD domain - - - 0.0000000003519 71.0
CSH2_k127_6114786_2 Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 304.0
CSH2_k127_6114786_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 306.0
CSH2_k127_6114786_4 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001265 278.0
CSH2_k127_6114786_5 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001385 247.0
CSH2_k127_6114786_6 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000001684 223.0
CSH2_k127_6114786_7 Desulfoferrodoxin ferrous iron-binding domain K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000001705 196.0
CSH2_k127_6114786_8 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000001429 192.0
CSH2_k127_6114786_9 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000003664 196.0
CSH2_k127_613368_0 helicase superfamily c-terminal domain K03724 - - 1.619e-256 821.0
CSH2_k127_613368_1 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000000000000000000000000000009562 121.0
CSH2_k127_613368_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000001163 108.0
CSH2_k127_613368_3 DNA-binding transcription factor activity - - - 0.0000000000000000008594 88.0
CSH2_k127_613368_4 - - - - 0.000000004104 62.0
CSH2_k127_6135624_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 514.0
CSH2_k127_6135624_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 308.0
CSH2_k127_6135624_10 Periplasmic copper-binding protein (NosD) - - - 0.000000000000008269 86.0
CSH2_k127_6135624_11 PFAM FIST C domain - - - 0.000001811 60.0
CSH2_k127_6135624_2 PFAM PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001587 276.0
CSH2_k127_6135624_3 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000044 194.0
CSH2_k127_6135624_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.000000000000000000000000000000000000000000000000002261 190.0
CSH2_k127_6135624_5 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000002241 189.0
CSH2_k127_6135624_6 SMART Prolyl 4-hydroxylase, alpha subunit - - - 0.000000000000000000000000000000000000002016 162.0
CSH2_k127_6135624_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000001329 152.0
CSH2_k127_6135624_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP - - - 0.000000000000000000000000001898 124.0
CSH2_k127_6135624_9 Polyprenyl synthetase K02523,K13787 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000006224 113.0
CSH2_k127_6149228_0 Iron-containing alcohol dehydrogenase K19955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 442.0
CSH2_k127_6149228_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000007065 209.0
CSH2_k127_6149228_2 Zn_pept - - - 0.000000000000000000000000005826 128.0
CSH2_k127_6149228_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00001138 54.0
CSH2_k127_6155467_0 Proprotein convertase P-domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 570.0
CSH2_k127_6155467_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001312 238.0
CSH2_k127_6279635_0 calcium- and calmodulin-responsive adenylate cyclase activity K13735,K20276,K21449 - - 0.00000000000000000000000000000000000000000000000000000000000000000001544 256.0
CSH2_k127_6279635_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000005351 248.0
CSH2_k127_6279635_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000006733 79.0
CSH2_k127_6279635_3 Arylsulfotransferase (ASST) - - - 0.0000000002403 67.0
CSH2_k127_6396472_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 599.0
CSH2_k127_6396472_1 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 466.0
CSH2_k127_6396472_2 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000007803 240.0
CSH2_k127_6396472_3 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000001917 181.0
CSH2_k127_6396472_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000005978 178.0
CSH2_k127_6396472_5 KEOPS complex Cgi121-like subunit K09119 - - 0.00000000000000005296 87.0
CSH2_k127_6396472_6 dihydromethanopterin reductase activity K00176,K06411,K12527 - 1.2.7.3,1.97.1.9 0.0000000000000002721 81.0
CSH2_k127_6396472_7 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000002826 81.0
CSH2_k127_6396472_8 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.0003526 52.0
CSH2_k127_6507597_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1587.0
CSH2_k127_6507597_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 4.203e-241 767.0
CSH2_k127_6507597_10 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 366.0
CSH2_k127_6507597_11 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 367.0
CSH2_k127_6507597_12 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 360.0
CSH2_k127_6507597_13 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 355.0
CSH2_k127_6507597_14 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036,K02068,K06857 - 3.6.3.27,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 317.0
CSH2_k127_6507597_15 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 304.0
CSH2_k127_6507597_16 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 298.0
CSH2_k127_6507597_17 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 295.0
CSH2_k127_6507597_18 Pheromone shutdown protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 299.0
CSH2_k127_6507597_19 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003025 276.0
CSH2_k127_6507597_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.046e-217 700.0
CSH2_k127_6507597_20 Diphthamide K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004377 278.0
CSH2_k127_6507597_21 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000002273 267.0
CSH2_k127_6507597_22 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002181 261.0
CSH2_k127_6507597_23 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002427 254.0
CSH2_k127_6507597_24 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003464 254.0
CSH2_k127_6507597_25 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003939 259.0
CSH2_k127_6507597_26 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004828 256.0
CSH2_k127_6507597_27 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004408 246.0
CSH2_k127_6507597_28 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008716 241.0
CSH2_k127_6507597_29 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000000000000000000000000000000000000000000000000001975 233.0
CSH2_k127_6507597_3 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 5.764e-196 622.0
CSH2_k127_6507597_30 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000002349 226.0
CSH2_k127_6507597_31 BioY protein K03523 - - 0.0000000000000000000000000000000000000000000000000000000000000003923 228.0
CSH2_k127_6507597_32 PFAM Histone deacetylase K04768 - - 0.000000000000000000000000000000000000000000000000000000000000001835 231.0
CSH2_k127_6507597_33 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000002396 211.0
CSH2_k127_6507597_34 - - - - 0.000000000000000000000000000000000000000000000000000000006803 208.0
CSH2_k127_6507597_35 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000005008 198.0
CSH2_k127_6507597_36 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000005895 191.0
CSH2_k127_6507597_37 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000008947 183.0
CSH2_k127_6507597_38 Ribosomal protein L30p/L7e K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001548 183.0
CSH2_k127_6507597_39 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000006319 184.0
CSH2_k127_6507597_4 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 572.0
CSH2_k127_6507597_40 DNA repair and recombination protein RadB K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000001164 178.0
CSH2_k127_6507597_41 Evidence 5 No homology to any previously reported sequences K01361,K13277 - 3.4.21.96 0.00000000000000000000000000000000000000000000003831 185.0
CSH2_k127_6507597_42 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000002192 170.0
CSH2_k127_6507597_43 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000009704 169.0
CSH2_k127_6507597_44 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001183 170.0
CSH2_k127_6507597_45 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000009504 161.0
CSH2_k127_6507597_46 Protein of unknown function (DUF401) K09133 - - 0.0000000000000000000000000000000000000001699 166.0
CSH2_k127_6507597_47 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000002581 146.0
CSH2_k127_6507597_48 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001048 145.0
CSH2_k127_6507597_49 Binds to the 23S rRNA K02929 - - 0.000000000000000000000000000000000003391 140.0
CSH2_k127_6507597_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 470.0
CSH2_k127_6507597_50 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000004054 145.0
CSH2_k127_6507597_51 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000002883 139.0
CSH2_k127_6507597_52 PIN domain of ribonuclease K07060 - - 0.0000000000000000000000000008425 119.0
CSH2_k127_6507597_53 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000001496 123.0
CSH2_k127_6507597_54 Hydrogenase maturation protease K03605 - - 0.000000000000000000000001267 108.0
CSH2_k127_6507597_55 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000005211 107.0
CSH2_k127_6507597_56 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000003369 101.0
CSH2_k127_6507597_57 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000000008817 109.0
CSH2_k127_6507597_58 Aminotransferase - - - 0.000000000000000000006186 106.0
CSH2_k127_6507597_59 Ribosomal protein L23 K02892 - - 0.000000000000000003227 89.0
CSH2_k127_6507597_6 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 419.0
CSH2_k127_6507597_60 ribosomal protein S14 K02954 - - 0.00000000000000000362 84.0
CSH2_k127_6507597_61 - - - - 0.000000000000000008698 93.0
CSH2_k127_6507597_62 Ribosomal L29 protein K02904 - - 0.00000000000000003935 82.0
CSH2_k127_6507597_63 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000001653 81.0
CSH2_k127_6507597_64 PFAM Ribosomal protein S27E K02978 - - 0.00000000000000017 80.0
CSH2_k127_6507597_65 PFAM SMP-30 Gluconolaconase - - - 0.000000000000001188 89.0
CSH2_k127_6507597_67 protein conserved in archaea K09723 - - 0.00000000007034 70.0
CSH2_k127_6507597_68 COG2002 Regulators of stationary sporulation gene expression - - - 0.000000001448 60.0
CSH2_k127_6507597_69 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000006154 58.0
CSH2_k127_6507597_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 398.0
CSH2_k127_6507597_70 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000001984 53.0
CSH2_k127_6507597_8 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 406.0
CSH2_k127_6507597_9 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 381.0
CSH2_k127_6522090_0 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000002051 92.0
CSH2_k127_6522090_1 integral membrane protein - - - 0.0000000000000004584 91.0
CSH2_k127_6522090_2 PFAM Peptidase C1A, papain - - - 0.000000000000002145 89.0
CSH2_k127_6522090_3 Protein of unknown function (DUF996) - - - 0.0000000000006775 77.0
CSH2_k127_6522090_4 GxGYxYP putative glycoside hydrolase C-terminal domain K03088 - - 0.00001107 57.0
CSH2_k127_6522090_5 Flavodoxin K03809 - 1.6.5.2 0.00005527 51.0
CSH2_k127_6630605_0 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 402.0
CSH2_k127_6630605_1 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 391.0
CSH2_k127_6630605_10 chitinase K01183 - 3.2.1.14 0.000000000000002403 90.0
CSH2_k127_6630605_11 PKD domain - - - 0.0000000000002324 84.0
CSH2_k127_6630605_12 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA - - - 0.000005684 57.0
CSH2_k127_6630605_13 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00004176 56.0
CSH2_k127_6630605_2 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 324.0
CSH2_k127_6630605_3 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 311.0
CSH2_k127_6630605_4 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000002589 237.0
CSH2_k127_6630605_5 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000543 177.0
CSH2_k127_6630605_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000001117 156.0
CSH2_k127_6630605_7 - - - - 0.00000000000000000000000000000000000003587 149.0
CSH2_k127_6630605_8 Acetyltransferase (GNAT) domain K03823 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 0.00000000000000000000000000000000003453 140.0
CSH2_k127_6630605_9 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000001283 147.0
CSH2_k127_6763176_0 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003103 243.0
CSH2_k127_6763176_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000001991 155.0
CSH2_k127_6763176_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000004844 109.0
CSH2_k127_6763176_3 deoxyribonucleoside 5'-monophosphate N-glycosidase activity K09457 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 1.7.1.13 0.00000134 57.0
CSH2_k127_856741_0 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000005838 106.0
CSH2_k127_856741_1 Acyl-protein synthetase, LuxE - - - 0.00000000000000000005933 103.0
CSH2_k127_856741_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000001695 89.0
CSH2_k127_856741_3 Hexapeptide repeat of succinyl-transferase - - - 0.000000000001583 77.0
CSH2_k127_856741_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0005037 51.0
CSH2_k127_903841_0 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 479.0
CSH2_k127_903841_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 361.0
CSH2_k127_903841_2 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 334.0
CSH2_k127_903841_3 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 321.0
CSH2_k127_903841_4 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000003592 236.0
CSH2_k127_903841_5 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000001455 220.0
CSH2_k127_903841_6 PFAM LemA - - - 0.000000000000000000000000000000000000000000000000000000000001269 214.0
CSH2_k127_903841_7 Flavodoxin - - - 0.000000000131 68.0
CSH2_k127_903841_8 - - - - 0.0006898 49.0
CSH2_k127_904075_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 388.0
CSH2_k127_904075_1 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 317.0
CSH2_k127_904075_10 PFAM PKD domain containing protein - - - 0.0000000006653 69.0
CSH2_k127_904075_11 alpha beta - - - 0.0000001273 63.0
CSH2_k127_904075_12 - - - - 0.0000004251 58.0
CSH2_k127_904075_13 Protein of unknown function (DUF2510) - - - 0.0000754 52.0
CSH2_k127_904075_14 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0001023 50.0
CSH2_k127_904075_15 AsnC-type helix-turn-helix domain - - - 0.0005125 49.0
CSH2_k127_904075_16 Ferritin-like domain - - - 0.000791 51.0
CSH2_k127_904075_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000001588 224.0
CSH2_k127_904075_3 - K03561,K12287 - - 0.000000000000000000000000000000000000000000002232 188.0
CSH2_k127_904075_4 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.000000000000000000008485 108.0
CSH2_k127_904075_5 PFAM NHL repeat containing protein - - - 0.0000000000000000005428 101.0
CSH2_k127_904075_6 double-strand break repair K01867,K09946 - 6.1.1.2 0.000000000000000004003 87.0
CSH2_k127_904075_7 Subtilase family - - - 0.0000000000000006202 91.0
CSH2_k127_904075_8 bacterial-type flagellum-dependent cell motility K01278,K02388,K02396,K03561,K12287 - 3.4.14.5 0.00000000000002417 85.0
CSH2_k127_904075_9 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000002921 78.0
CSH2_k127_94192_0 PFAM Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000001602 193.0
CSH2_k127_94192_1 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000003965 156.0