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Overview

ID MAG00622
Name CSH2_bin.9
Sample SMP0014
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Syntrophia
Order Syntrophales
Family UBA2185
Genus UBA2185
Species
Assembly information
Completeness (%) 70.44
Contamination (%) 0.67
GC content (%) 47.0
N50 (bp) 4,907
Genome size (bp) 1,060,598

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1081

Gene name Description KEGG GOs EC E-value Score Sequence
CSH2_k127_1004337_0 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0 1163.0
CSH2_k127_1004337_1 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 587.0
CSH2_k127_1004337_10 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000000000000000001351 180.0
CSH2_k127_1004337_11 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000001481 153.0
CSH2_k127_1004337_12 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000004599 96.0
CSH2_k127_1004337_13 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000002151 86.0
CSH2_k127_1004337_14 - - - - 0.0000000000000001272 81.0
CSH2_k127_1004337_15 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000252 67.0
CSH2_k127_1004337_2 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 374.0
CSH2_k127_1004337_3 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 321.0
CSH2_k127_1004337_4 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 310.0
CSH2_k127_1004337_5 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 309.0
CSH2_k127_1004337_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000003745 259.0
CSH2_k127_1004337_7 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000000000000000000000006097 226.0
CSH2_k127_1004337_8 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000001714 224.0
CSH2_k127_1004337_9 AMMECR1 K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000007372 212.0
CSH2_k127_1007650_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 381.0
CSH2_k127_1007650_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005048 281.0
CSH2_k127_1007650_2 KWG Leptospira - - - 0.00000000000000000000000000000000000000000000000003061 189.0
CSH2_k127_1007650_3 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000003169 116.0
CSH2_k127_1023047_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 603.0
CSH2_k127_1023047_1 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 404.0
CSH2_k127_1023047_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004914 267.0
CSH2_k127_1023047_3 - - - - 0.00000000000000000001635 91.0
CSH2_k127_1023047_4 - - - - 0.000000000000005339 76.0
CSH2_k127_1035052_0 Acetyl-CoA hydrolase transferase N-terminal domain - - - 1.678e-251 791.0
CSH2_k127_1035052_1 cAMP biosynthetic process - - - 6.055e-217 687.0
CSH2_k127_1035052_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 6.678e-210 659.0
CSH2_k127_1035052_3 hydrolase of the alpha beta-hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 298.0
CSH2_k127_1035052_4 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000001666 206.0
CSH2_k127_103970_0 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 1.486e-216 681.0
CSH2_k127_103970_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 8.211e-204 658.0
CSH2_k127_103970_2 Integrase K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 333.0
CSH2_k127_103970_3 Transposase - - - 0.0000000000000000000000000000000000000000000001008 169.0
CSH2_k127_103970_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000001378 159.0
CSH2_k127_103970_5 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000009808 134.0
CSH2_k127_103970_6 CHAD domain containing protein - - - 0.00000000000000000000000000001094 134.0
CSH2_k127_1053372_0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002081 279.0
CSH2_k127_1053372_1 - - - - 0.000000000000000000000000000000000000000000003975 170.0
CSH2_k127_1053372_2 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 0.00000000000004331 72.0
CSH2_k127_1080946_0 CorA-like Mg2+ transporter protein K03284 GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 332.0
CSH2_k127_1080946_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 330.0
CSH2_k127_1080946_2 Transcriptional regulator - - - 0.000000000000004773 83.0
CSH2_k127_1080946_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000009285 64.0
CSH2_k127_1093371_0 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 0.0 1752.0
CSH2_k127_1152038_0 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 442.0
CSH2_k127_1152038_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 389.0
CSH2_k127_1152038_2 PFAM NIL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006592 224.0
CSH2_k127_1152038_3 - K07020,K18614 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0034641,GO:0042365,GO:0042737,GO:0042802,GO:0042803,GO:0042816,GO:0042820,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046983,GO:0047411,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.1.29 0.000000000000000000000000000000000000000000000000000001845 196.0
CSH2_k127_1156139_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1081.0
CSH2_k127_1156139_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000001034 183.0
CSH2_k127_1156139_2 Nitroreductase family - - - 0.0000000000003396 74.0
CSH2_k127_1156139_3 protocatechuate 3,4-dioxygenase activity - - - 0.0003976 51.0
CSH2_k127_125542_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 3.633e-220 692.0
CSH2_k127_125542_1 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 298.0
CSH2_k127_125542_2 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001709 259.0
CSH2_k127_125542_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005434 245.0
CSH2_k127_125542_4 FeS assembly protein SUFB K09014 - - 0.000000000000000000000000000000000000000002987 160.0
CSH2_k127_1287648_0 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003683 284.0
CSH2_k127_1287648_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008486 275.0
CSH2_k127_1287648_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000009779 152.0
CSH2_k127_1287648_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000002931 52.0
CSH2_k127_1304665_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 566.0
CSH2_k127_1304665_1 Fe-S center protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 484.0
CSH2_k127_1304665_2 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000005501 210.0
CSH2_k127_1316490_0 PFAM Alpha amylase K00700 - 2.4.1.18 0.0 1084.0
CSH2_k127_1316490_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703,K01176 - 2.4.1.21,3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 486.0
CSH2_k127_1316490_2 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000003246 119.0
CSH2_k127_1316490_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000229 88.0
CSH2_k127_1324669_0 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000004627 220.0
CSH2_k127_1361386_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 7.582e-243 755.0
CSH2_k127_1361386_1 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 510.0
CSH2_k127_1361386_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 383.0
CSH2_k127_1361386_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 317.0
CSH2_k127_1361386_4 Belongs to the UPF0102 family K07460 - - 0.00000000000009751 73.0
CSH2_k127_1361386_6 - - - - 0.000002642 58.0
CSH2_k127_1410644_0 Lipoprotein - - - 6.906e-307 957.0
CSH2_k127_1441104_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 9.588e-221 698.0
CSH2_k127_1441104_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 298.0
CSH2_k127_1441104_2 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000155 278.0
CSH2_k127_1441104_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000006911 234.0
CSH2_k127_1441104_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001603 231.0
CSH2_k127_1441104_5 PFAM NifU-like domain - - - 0.0000000000000000000000000006228 114.0
CSH2_k127_1441104_6 indolepyruvate ferredoxin oxidoreductase activity K00179,K05524 - 1.2.7.8 0.0000000000000000000000000008455 112.0
CSH2_k127_1469505_0 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 542.0
CSH2_k127_1484091_0 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 394.0
CSH2_k127_1484091_1 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.0000000000000000000000000000000000000000000003149 174.0
CSH2_k127_1487204_0 Tyrosine recombinase XerD K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 415.0
CSH2_k127_1487204_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 339.0
CSH2_k127_1487204_2 cell septum assembly - - - 0.000000000000000000000000000000000000000000000000000000000009439 219.0
CSH2_k127_1491367_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.43e-315 977.0
CSH2_k127_1491367_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 314.0
CSH2_k127_1491367_2 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001517 288.0
CSH2_k127_1491367_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002098 253.0
CSH2_k127_1491367_4 Sporulation and spore germination - - - 0.000000000000000000000000000000000000000000000000000001583 198.0
CSH2_k127_1491367_5 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000002845 132.0
CSH2_k127_1533326_0 response regulator K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 610.0
CSH2_k127_1533326_1 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000008676 233.0
CSH2_k127_1533326_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.0000000000000000000000006995 107.0
CSH2_k127_1533326_3 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000008507 51.0
CSH2_k127_1534056_0 acetyl-CoA K18122 - - 1.475e-269 835.0
CSH2_k127_1534056_1 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 413.0
CSH2_k127_1534056_2 CoA-transferase activity K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 284.0
CSH2_k127_1534056_3 Short chain fatty acid transporter K02106 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000004468 204.0
CSH2_k127_1542826_0 PFAM Type II IV secretion system protein K02669 - - 2.557e-206 644.0
CSH2_k127_1542826_1 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 9.126e-195 614.0
CSH2_k127_1542826_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004493 268.0
CSH2_k127_1542826_3 - - - - 0.000000000000000000000000000000000000000000004611 168.0
CSH2_k127_1542826_4 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000002713 162.0
CSH2_k127_1542826_5 Belongs to the HesB IscA family - - - 0.00000000000000002729 83.0
CSH2_k127_1712670_0 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000007262 228.0
CSH2_k127_1712670_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000002824 189.0
CSH2_k127_1715950_0 AAA domain K07028 - - 1.08e-203 647.0
CSH2_k127_1715950_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 289.0
CSH2_k127_1715950_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 292.0
CSH2_k127_1715950_3 Phosphorylase superfamily K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000345 279.0
CSH2_k127_1715950_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000009814 170.0
CSH2_k127_1715950_5 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000001785 160.0
CSH2_k127_1715950_6 - - - - 0.00000000000000000000000000000000000000001653 156.0
CSH2_k127_173307_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 584.0
CSH2_k127_173307_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 535.0
CSH2_k127_173307_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 383.0
CSH2_k127_173307_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 361.0
CSH2_k127_173307_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 353.0
CSH2_k127_173307_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002421 278.0
CSH2_k127_173307_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000002205 263.0
CSH2_k127_173307_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000001645 129.0
CSH2_k127_1748901_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 413.0
CSH2_k127_1748901_1 tRNA (guanine-N7-)-methyltransferase activity - - - 0.0000000000000000000000000000000000000000003128 168.0
CSH2_k127_1748901_2 RNA-binding protein - - - 0.000000000000000000002087 97.0
CSH2_k127_1748901_3 cold-shock protein K03704 - - 0.00000000000002691 72.0
CSH2_k127_1748901_4 - - - - 0.0000006275 54.0
CSH2_k127_1837519_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 493.0
CSH2_k127_1837519_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009467 293.0
CSH2_k127_1837519_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000003817 69.0
CSH2_k127_1837519_3 DNA polymerase beta domain protein region K07076 - - 0.000000000005518 72.0
CSH2_k127_1837519_4 Protein of unknown function DUF86 - - - 0.00000000002752 69.0
CSH2_k127_1863355_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000002458 187.0
CSH2_k127_1863355_1 cheY-homologous receiver domain - - - 0.000000146 55.0
CSH2_k127_1863756_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703,K01176 - 2.4.1.21,3.2.1.1 8.539e-235 741.0
CSH2_k127_1863756_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006374 279.0
CSH2_k127_1863756_2 lipolytic protein G-D-S-L family - - - 0.000000000000000332 86.0
CSH2_k127_188833_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 565.0
CSH2_k127_188833_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000001131 246.0
CSH2_k127_188833_2 Rhodanese Homology Domain - - - 0.0000000000000000000000003718 108.0
CSH2_k127_1904843_0 PFAM Acyl-CoA dehydrogenase K09456 - - 5.286e-202 646.0
CSH2_k127_1904843_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009357 398.0
CSH2_k127_1904843_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00003,K01139 - 1.1.1.3,2.7.6.5,3.1.7.2 0.000000000000000000000000000000000000000000000000000001546 198.0
CSH2_k127_1904843_3 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.000000000000000000000000000000000000000000000000003018 184.0
CSH2_k127_1904843_4 HD domain - - - 0.00000000000000000000000000000000000000001887 156.0
CSH2_k127_1904843_5 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000008703 135.0
CSH2_k127_1904843_6 Ferric uptake regulator family K03711,K09825 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000008861 101.0
CSH2_k127_1904843_7 - - - - 0.00000008984 57.0
CSH2_k127_1914554_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.021e-251 785.0
CSH2_k127_1914554_1 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 471.0
CSH2_k127_1914554_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000001758 246.0
CSH2_k127_1914554_3 Plasmid pRiA4b ORF-3-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000001365 221.0
CSH2_k127_1914554_4 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.00000000000000000000000000000000000000000000000000000000143 209.0
CSH2_k127_1914554_5 - - - - 0.0000000000000000000000000000000001032 137.0
CSH2_k127_1914554_6 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000001271 139.0
CSH2_k127_1914554_7 PFAM Helix-turn-helix - - - 0.000000000000000000000000000000009744 128.0
CSH2_k127_1914554_8 - - - - 0.000000000000000001553 91.0
CSH2_k127_1918522_0 nucleotide catabolic process K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 594.0
CSH2_k127_1918522_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000001791 124.0
CSH2_k127_1918522_2 - - - - 0.00000000000000000000000002344 115.0
CSH2_k127_1918522_3 4Fe-4S binding domain - - - 0.000000000001357 68.0
CSH2_k127_1940321_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.838e-309 959.0
CSH2_k127_1940321_1 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 306.0
CSH2_k127_1940321_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000004434 207.0
CSH2_k127_1940321_3 'dna polymerase iii K02341 - 2.7.7.7 0.0001057 49.0
CSH2_k127_2116129_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.897e-295 914.0
CSH2_k127_2116129_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 7.273e-251 784.0
CSH2_k127_2116129_2 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 359.0
CSH2_k127_2116129_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 336.0
CSH2_k127_2116129_4 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000000000000000000000001988 167.0
CSH2_k127_2116129_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001554 148.0
CSH2_k127_2116129_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000958 148.0
CSH2_k127_2128391_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 569.0
CSH2_k127_2128391_1 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.0000000000000000007539 88.0
CSH2_k127_2177364_0 FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 494.0
CSH2_k127_2177364_1 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 407.0
CSH2_k127_2177364_2 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 406.0
CSH2_k127_2177364_3 antitermination protein NusG K05785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004138 261.0
CSH2_k127_2177364_4 PFAM Class I peptide chain release factor - - - 0.000000000000000000000000000000000000000000000004976 175.0
CSH2_k127_2177364_5 SMART regulatory protein AsnC Lrp family - - - 0.000000004935 59.0
CSH2_k127_2248515_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.681e-199 627.0
CSH2_k127_2248515_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 573.0
CSH2_k127_2248515_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 545.0
CSH2_k127_2248515_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 293.0
CSH2_k127_2248515_4 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000000001281 121.0
CSH2_k127_2248515_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000003888 72.0
CSH2_k127_2282559_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 523.0
CSH2_k127_2282559_1 SMART Cold shock protein K03704 - - 0.000000000000000000000000000008332 119.0
CSH2_k127_2282559_2 RNA-binding protein - - - 0.0000000000000000004237 91.0
CSH2_k127_2324680_0 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000003531 141.0
CSH2_k127_2324680_1 SMART Cold shock protein K03704 - - 0.000000000000000000000000001328 112.0
CSH2_k127_2324680_2 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000001118 94.0
CSH2_k127_2324680_3 - - - - 0.00000000000000004746 84.0
CSH2_k127_2324680_4 - - - - 0.0000001004 65.0
CSH2_k127_23719_0 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 571.0
CSH2_k127_23719_1 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 552.0
CSH2_k127_23719_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000293 157.0
CSH2_k127_23719_3 radical SAM domain protein - - - 0.0000000000000000000251 90.0
CSH2_k127_2373662_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 1.35e-203 638.0
CSH2_k127_2373662_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000009872 250.0
CSH2_k127_2373662_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000001355 222.0
CSH2_k127_2373662_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000003837 137.0
CSH2_k127_2414904_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.555e-256 797.0
CSH2_k127_2414904_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.623e-218 682.0
CSH2_k127_243905_0 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 318.0
CSH2_k127_243905_1 PFAM MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009859 248.0
CSH2_k127_243905_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000008481 239.0
CSH2_k127_243905_3 TIGRFAM RecB family nuclease - - - 0.000000000000000000000000000000000000006264 163.0
CSH2_k127_243905_4 Aconitase C-terminal domain K01681 - 4.2.1.3 0.00000000002195 65.0
CSH2_k127_24550_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 504.0
CSH2_k127_24550_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 367.0
CSH2_k127_24550_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000002744 222.0
CSH2_k127_24550_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000006375 187.0
CSH2_k127_2455758_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000619 263.0
CSH2_k127_2455758_1 Chromosomal replication initiator, DnaA K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001567 259.0
CSH2_k127_2455758_2 IMG reference gene - - - 0.00000000000000000000000000000000000004072 152.0
CSH2_k127_245664_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 468.0
CSH2_k127_245664_1 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 350.0
CSH2_k127_2557781_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 498.0
CSH2_k127_2557781_1 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 317.0
CSH2_k127_2557781_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005852 269.0
CSH2_k127_2557781_3 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000000000000005314 197.0
CSH2_k127_2557781_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000001166 124.0
CSH2_k127_2558776_0 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 536.0
CSH2_k127_2558776_1 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 536.0
CSH2_k127_2558776_2 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 387.0
CSH2_k127_2568699_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.581e-195 616.0
CSH2_k127_2568699_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000000000002759 190.0
CSH2_k127_2568699_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000002846 152.0
CSH2_k127_2568699_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3 0.000000000000000000000000001147 114.0
CSH2_k127_2568699_4 Transglycosylase K08309 - - 0.00000000000000001358 83.0
CSH2_k127_2568699_5 Helix-hairpin-helix motif K02237 - - 0.0000000000000001372 89.0
CSH2_k127_2599018_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 509.0
CSH2_k127_2599018_1 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009724 399.0
CSH2_k127_2599018_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000001027 244.0
CSH2_k127_2599018_3 - - - - 0.000000000000000000000000000000000000000000000000000001599 199.0
CSH2_k127_2599018_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000001405 190.0
CSH2_k127_2599018_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000003071 61.0
CSH2_k127_2617610_0 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 340.0
CSH2_k127_2617610_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001406 265.0
CSH2_k127_2617610_2 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000001128 216.0
CSH2_k127_2617610_3 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000000007535 164.0
CSH2_k127_2617610_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000008045 157.0
CSH2_k127_2617610_5 Helix-turn-helix domain - - - 0.0000000000000002662 86.0
CSH2_k127_2617610_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000001505 78.0
CSH2_k127_26253_0 Bacterial type II and III secretion system protein K12282 - - 0.000000000000000000000000000000000000000000002025 173.0
CSH2_k127_2627668_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000004448 233.0
CSH2_k127_2627668_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000003984 174.0
CSH2_k127_2627668_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000856 62.0
CSH2_k127_2633264_0 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 398.0
CSH2_k127_2633264_1 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 369.0
CSH2_k127_2633264_2 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 354.0
CSH2_k127_2633264_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000004472 199.0
CSH2_k127_2633264_4 - - - - 0.000000000000000000000000000000000000000000001211 178.0
CSH2_k127_2635770_0 lysine 2,3-aminomutase activity K01843,K19810 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 574.0
CSH2_k127_2635770_1 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 469.0
CSH2_k127_2635770_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 345.0
CSH2_k127_2635770_3 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 301.0
CSH2_k127_2635770_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005592 277.0
CSH2_k127_2635770_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673,K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000002973 216.0
CSH2_k127_2635770_6 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.000000000005652 76.0
CSH2_k127_2635770_7 acetyltransferase K18815 - 2.3.1.82 0.000001013 52.0
CSH2_k127_2645352_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 478.0
CSH2_k127_2645352_1 General secretory system II protein E domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 447.0
CSH2_k127_2645352_2 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 429.0
CSH2_k127_2645352_3 - - - - 0.000000000000000000000000000000000000000000006604 176.0
CSH2_k127_2645352_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000009796 147.0
CSH2_k127_2645798_0 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 517.0
CSH2_k127_2645798_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 314.0
CSH2_k127_2645798_2 - K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006155 256.0
CSH2_k127_2645798_3 Type II and III secretion system protein K12282 - - 0.00000000000000000000000000000003914 133.0
CSH2_k127_2645814_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 1.484e-204 644.0
CSH2_k127_2645814_1 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000005952 180.0
CSH2_k127_2645814_2 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000001925 132.0
CSH2_k127_2685159_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 1.449e-202 638.0
CSH2_k127_2685159_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 420.0
CSH2_k127_2685159_2 PFAM ParB domain protein nuclease K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001653 248.0
CSH2_k127_2685159_3 DNA topoisomerase II activity K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.00000000000000000000000000000000000000000000004174 171.0
CSH2_k127_2685159_4 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000001578 58.0
CSH2_k127_2703811_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713,K07714 - - 2.003e-207 652.0
CSH2_k127_2703811_1 Beta-lactamase enzyme family K07258,K07262 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000002787 189.0
CSH2_k127_2748578_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 603.0
CSH2_k127_2748578_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000001264 206.0
CSH2_k127_2779204_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 8.609e-256 802.0
CSH2_k127_2779204_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 421.0
CSH2_k127_2811659_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 436.0
CSH2_k127_2811659_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000118 161.0
CSH2_k127_2812655_0 7TM-HD extracellular K07037 - - 4.037e-236 753.0
CSH2_k127_2812655_1 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 532.0
CSH2_k127_2812655_2 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 497.0
CSH2_k127_2812655_3 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 316.0
CSH2_k127_2812655_4 Uncharacterized protein family UPF0054 K07042 - - 0.000000000000000000000005183 108.0
CSH2_k127_2812655_5 Lysin motif K08307 - - 0.00000000000000000004006 94.0
CSH2_k127_2828863_0 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 399.0
CSH2_k127_2828863_1 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 325.0
CSH2_k127_282956_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 602.0
CSH2_k127_282956_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 387.0
CSH2_k127_282956_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000004203 162.0
CSH2_k127_282956_3 Lipoprotein - - - 0.0000000000108 65.0
CSH2_k127_2830518_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 508.0
CSH2_k127_2830518_1 Acyl-CoA dehydrogenase, middle domain K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 472.0
CSH2_k127_2830518_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000219 250.0
CSH2_k127_2830518_3 PFAM Electron transfer flavoprotein K03521 - - 0.000000000000009732 74.0
CSH2_k127_2835934_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.882e-278 859.0
CSH2_k127_2835934_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 7.455e-214 667.0
CSH2_k127_2835934_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 400.0
CSH2_k127_2946380_0 Type VI secretion protein IcmF C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 544.0
CSH2_k127_2946380_1 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 434.0
CSH2_k127_2946380_2 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 352.0
CSH2_k127_2946380_3 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007847 243.0
CSH2_k127_29757_0 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 578.0
CSH2_k127_29757_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 498.0
CSH2_k127_29757_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008408 410.0
CSH2_k127_29757_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 290.0
CSH2_k127_29757_4 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 287.0
CSH2_k127_29757_5 acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000007341 258.0
CSH2_k127_29757_6 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000009574 124.0
CSH2_k127_29757_7 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000008906 100.0
CSH2_k127_29757_8 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.00000004705 55.0
CSH2_k127_304916_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.041e-266 834.0
CSH2_k127_304916_1 PFAM Transposase IS200 like - - - 0.00000000000000000000000000000000001222 141.0
CSH2_k127_3067735_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000709 213.0
CSH2_k127_3072800_0 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 522.0
CSH2_k127_3072800_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 439.0
CSH2_k127_3072800_2 Formiminotransferase domain, N-terminal subdomain K00603 - 2.1.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 337.0
CSH2_k127_3072800_3 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002952 280.0
CSH2_k127_3072800_4 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002313 252.0
CSH2_k127_3072800_5 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.00000000000000000000000000000001393 134.0
CSH2_k127_3072800_6 - - - - 0.0000007346 55.0
CSH2_k127_3096253_0 formate C-acetyltransferase glycine radical - - - 1.562e-203 661.0
CSH2_k127_3096253_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 324.0
CSH2_k127_3096253_2 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000001071 218.0
CSH2_k127_3096253_3 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000002576 165.0
CSH2_k127_3096253_4 PFAM ATP synthase I chain - - - 0.00000000000000000000000000000001957 130.0
CSH2_k127_3096253_6 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000001998 61.0
CSH2_k127_3096253_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000008227 55.0
CSH2_k127_3124331_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 462.0
CSH2_k127_3124331_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 381.0
CSH2_k127_3124331_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000001663 203.0
CSH2_k127_3124331_3 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases K01628,K03077 - 4.1.2.17,5.1.3.4 0.000000000000000000000000000000000000008357 153.0
CSH2_k127_3127870_0 Bacterial regulatory protein, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 567.0
CSH2_k127_3127870_1 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 513.0
CSH2_k127_3157315_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 524.0
CSH2_k127_3157315_1 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 479.0
CSH2_k127_3157315_2 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 314.0
CSH2_k127_3157315_3 curli production assembly transport component CsgG - - - 0.000000001165 70.0
CSH2_k127_3339256_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1813.0
CSH2_k127_3339256_1 Glutamine phosphoribosylpyrophosphate amidotransferase K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 537.0
CSH2_k127_3339256_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 281.0
CSH2_k127_336043_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.0 1023.0
CSH2_k127_336043_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00033,K00616,K01810,K08300,K13810 - 1.1.1.343,1.1.1.44,2.2.1.2,3.1.26.12,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 429.0
CSH2_k127_336043_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 381.0
CSH2_k127_336043_3 ABC transporter K01990 - - 0.0000032 51.0
CSH2_k127_3411174_0 lactate racemase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 374.0
CSH2_k127_3411174_1 binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 317.0
CSH2_k127_3411174_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000001516 229.0
CSH2_k127_3411174_4 Protein of unknown function (DUF3800) - - - 0.000000655 53.0
CSH2_k127_3442137_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 527.0
CSH2_k127_3442137_1 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000004722 218.0
CSH2_k127_3493264_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 498.0
CSH2_k127_3493264_1 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 389.0
CSH2_k127_3493264_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 390.0
CSH2_k127_3493264_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000005655 235.0
CSH2_k127_3493264_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000000000000001985 201.0
CSH2_k127_3493264_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000001063 198.0
CSH2_k127_3493264_6 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000443 138.0
CSH2_k127_3493264_7 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000002016 114.0
CSH2_k127_3493264_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13598 - 2.7.13.3 0.0000000000000000008653 89.0
CSH2_k127_3493840_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1005.0
CSH2_k127_3493840_1 Universal stress protein - - - 0.00000000000000000000000000000000000000003572 155.0
CSH2_k127_3534593_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703,K01176 - 2.4.1.21,3.2.1.1 5.037e-281 875.0
CSH2_k127_3544342_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.441e-299 925.0
CSH2_k127_3544342_1 Tim44 K02117,K08678,K11646,K15539,K17835,K21636 - 1.1.98.6,1.4.1.24,3.6.3.14,3.6.3.15,4.1.1.35,4.1.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 542.0
CSH2_k127_3544342_2 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 389.0
CSH2_k127_3544342_3 TIGRFAM methylmalonyl-CoA mutase C-terminal domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000002347 210.0
CSH2_k127_3544342_4 PFAM type IV pilus assembly PilZ - - - 0.00000000000000000000000000008007 121.0
CSH2_k127_3544342_5 Dodecin K09165 - - 0.000000000000325 70.0
CSH2_k127_3545415_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 353.0
CSH2_k127_3545415_1 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000003268 175.0
CSH2_k127_3554892_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 5.374e-259 803.0
CSH2_k127_3554892_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 8.55e-210 665.0
CSH2_k127_3554892_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 492.0
CSH2_k127_3554892_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 411.0
CSH2_k127_3554892_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000003926 264.0
CSH2_k127_3554892_5 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008184 245.0
CSH2_k127_3554892_6 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000009459 217.0
CSH2_k127_3554892_7 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000004274 174.0
CSH2_k127_3566337_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 5.883e-212 666.0
CSH2_k127_3566337_1 Endoribonuclease that initiates mRNA decay K18682 - - 5.617e-201 632.0
CSH2_k127_3566337_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 373.0
CSH2_k127_3566337_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001925 273.0
CSH2_k127_3566337_4 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000159 267.0
CSH2_k127_3566337_5 PFAM CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005845 257.0
CSH2_k127_3566337_6 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000001118 94.0
CSH2_k127_3578426_0 Bacterial extracellular solute-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 424.0
CSH2_k127_3578426_1 TIGRFAM DNA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 404.0
CSH2_k127_3578426_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 314.0
CSH2_k127_3578426_3 Bacterial extracellular solute-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 297.0
CSH2_k127_3586766_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 509.0
CSH2_k127_3586766_1 PFAM Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 301.0
CSH2_k127_3586766_2 - - - - 0.000000000000000000000000000007606 135.0
CSH2_k127_3609904_0 Curli production assembly/transport component CsgG - - - 4.422e-249 784.0
CSH2_k127_3609904_1 PFAM Fibronectin, type III domain K01179,K06882 - 3.2.1.4 3.034e-235 749.0
CSH2_k127_3609904_2 Polysaccharide biosynthesis protein K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 336.0
CSH2_k127_3609904_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 292.0
CSH2_k127_3609904_5 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000004122 87.0
CSH2_k127_3617384_0 C-terminal, D2-small domain, of ClpB protein K03694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 435.0
CSH2_k127_3617384_1 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000001942 143.0
CSH2_k127_3617384_2 Dodecin K09165 - - 0.0000000000000000000000002842 107.0
CSH2_k127_3617384_3 Glycosyltransferase like family 2 - - - 0.0000001406 57.0
CSH2_k127_3619445_0 Type VI secretion system, TssF K11896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 457.0
CSH2_k127_3619445_1 type VI secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000002873 228.0
CSH2_k127_3619445_2 - - - - 0.00000000000000000000000000000000000000000000000004574 182.0
CSH2_k127_3619445_3 Type VI secretion system protein DotU K11892 - - 0.000000000000000000000000000000000001747 146.0
CSH2_k127_3619445_4 - - - - 0.00000000000000000000000000000000004362 139.0
CSH2_k127_3623729_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 349.0
CSH2_k127_3623729_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000001283 229.0
CSH2_k127_3623729_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001329 151.0
CSH2_k127_3623729_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000004008 136.0
CSH2_k127_3623729_4 - - - - 0.0000000000000000000000000000000003646 135.0
CSH2_k127_3623729_5 Cold-shock protein K03704 - - 0.000000003018 58.0
CSH2_k127_3623729_6 MJ0042 family finger-like protein - - - 0.00000001708 60.0
CSH2_k127_3625686_0 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 357.0
CSH2_k127_3625686_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 346.0
CSH2_k127_3625686_2 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 336.0
CSH2_k127_3625686_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 325.0
CSH2_k127_3625686_4 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000005371 204.0
CSH2_k127_3625686_5 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000228 185.0
CSH2_k127_3625686_6 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000000007449 171.0
CSH2_k127_3625686_7 Diguanylate cyclase - - - 0.0000002203 60.0
CSH2_k127_3631416_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13598 - 2.7.13.3 1.976e-285 894.0
CSH2_k127_3631416_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 6.038e-215 675.0
CSH2_k127_3631416_2 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 8.94e-212 685.0
CSH2_k127_3631416_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 496.0
CSH2_k127_3631416_4 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 438.0
CSH2_k127_3631416_5 Protein of unknown function (DUF3568) - - - 0.00000000000000000000000000000000000000009141 154.0
CSH2_k127_3631416_6 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000005389 145.0
CSH2_k127_3631416_8 Domain of unknown function (DUF4390) - - - 0.00000000000001608 74.0
CSH2_k127_3631416_9 Domain of unknown function (DUF4390) - - - 0.0000000000001275 76.0
CSH2_k127_3680129_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 597.0
CSH2_k127_3680129_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 520.0
CSH2_k127_3680129_2 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 325.0
CSH2_k127_3680129_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000136 267.0
CSH2_k127_3680129_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000002246 147.0
CSH2_k127_3680129_5 Alpha beta hydrolase - - - 0.000000000000000000000008057 103.0
CSH2_k127_3684939_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 3.866e-212 668.0
CSH2_k127_3684939_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.383e-203 636.0
CSH2_k127_3684939_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 595.0
CSH2_k127_3684939_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 531.0
CSH2_k127_3684939_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 466.0
CSH2_k127_3684939_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 434.0
CSH2_k127_3684939_6 Belongs to the SEDS family K03588 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 314.0
CSH2_k127_3684939_7 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 304.0
CSH2_k127_3684939_8 Essential cell division protein K03589 - - 0.0000000000000000000000000000000000000000001909 164.0
CSH2_k127_3693707_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 3.801e-236 740.0
CSH2_k127_3693707_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 522.0
CSH2_k127_3693707_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 443.0
CSH2_k127_3693707_3 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 306.0
CSH2_k127_3693707_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000001165 175.0
CSH2_k127_3693707_5 Preprotein translocase K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000131 138.0
CSH2_k127_3693707_6 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000004392 76.0
CSH2_k127_3716026_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 2.486e-234 740.0
CSH2_k127_3716026_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 361.0
CSH2_k127_3716026_2 - - - - 0.0000000000000000000000000000000000000000000000000000006253 194.0
CSH2_k127_3716026_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000001625 150.0
CSH2_k127_3716026_4 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000183 153.0
CSH2_k127_3716026_5 PFAM CoA-binding domain protein - - - 0.00000000000000000000000000000004247 128.0
CSH2_k127_3722167_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1122.0
CSH2_k127_3722167_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 310.0
CSH2_k127_3722167_10 Sporulation related domain - - - 0.0008917 49.0
CSH2_k127_3722167_2 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008565 241.0
CSH2_k127_3722167_3 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000000000000006006 227.0
CSH2_k127_3722167_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000221 175.0
CSH2_k127_3722167_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000252 142.0
CSH2_k127_3722167_6 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000001962 119.0
CSH2_k127_3722167_7 sequence-specific DNA binding - - - 0.000000001211 60.0
CSH2_k127_3722167_8 protein conserved in bacteria K15539 - - 0.00000000329 66.0
CSH2_k127_3722167_9 DnaJ-class molecular chaperone - - - 0.00003575 53.0
CSH2_k127_3732138_0 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001781 269.0
CSH2_k127_3749194_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 557.0
CSH2_k127_3749194_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 535.0
CSH2_k127_3749194_2 PFAM ABC transporter K01990,K01992,K09695 - - 0.000000000000000000000000000000000000000000000000000000000001048 211.0
CSH2_k127_3749194_3 Smr domain - - - 0.000000000000000000000000000000000000000000000000000001022 209.0
CSH2_k127_3749194_4 - - - - 0.00000000000000000000000000000003739 130.0
CSH2_k127_3772290_0 Transglutaminase/protease-like homologues - - - 2.643e-254 794.0
CSH2_k127_3772290_1 Phospholipase, patatin family K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002399 253.0
CSH2_k127_3772290_2 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000000000000000000000000000000000000000001643 168.0
CSH2_k127_3782968_0 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006851 271.0
CSH2_k127_3782968_1 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000036 256.0
CSH2_k127_3782968_2 PFAM Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000000000000000000001578 168.0
CSH2_k127_3782968_3 Pilus assembly protein, PilP K02664,K02665 - - 0.0000000000000000000000000008978 119.0
CSH2_k127_3782968_4 Tetratricopeptide repeat - - - 0.000006783 49.0
CSH2_k127_3784144_0 Heat shock 70 kDa protein K04043 - - 0.0 1071.0
CSH2_k127_3784144_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000002809 207.0
CSH2_k127_3784144_2 Periplasmic binding protein K07121 - - 0.000000004342 63.0
CSH2_k127_3792155_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 7.749e-256 797.0
CSH2_k127_3792155_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.64e-234 739.0
CSH2_k127_3792155_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000382 256.0
CSH2_k127_3852953_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 4.009e-312 980.0
CSH2_k127_3852953_1 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000004546 195.0
CSH2_k127_3852953_2 NADH-quinone oxidoreductase, E subunit K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.000000000000000000000000000000000000000000000000393 180.0
CSH2_k127_3852953_3 PHP-associated K07053 - 3.1.3.97 0.0000000000000000000000000000000000000001754 155.0
CSH2_k127_3852953_4 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000000001653 150.0
CSH2_k127_3856905_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 471.0
CSH2_k127_3856905_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 464.0
CSH2_k127_3856905_2 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000000427 113.0
CSH2_k127_3860021_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1098.0
CSH2_k127_3860021_1 PFAM Rubrerythrin - - - 0.000000000000000000000000000000006594 131.0
CSH2_k127_3860021_2 PFAM Membrane protein of K08972 - - 0.000000000000000000000000000006836 123.0
CSH2_k127_3904795_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 592.0
CSH2_k127_3904795_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000002485 68.0
CSH2_k127_3939371_0 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 477.0
CSH2_k127_3939371_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 328.0
CSH2_k127_3939371_2 Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008032 244.0
CSH2_k127_3939371_3 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000003779 229.0
CSH2_k127_3941010_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.788e-259 810.0
CSH2_k127_3941010_1 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 389.0
CSH2_k127_3941010_2 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001563 279.0
CSH2_k127_3941010_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000002972 149.0
CSH2_k127_3943081_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 332.0
CSH2_k127_3943081_1 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 290.0
CSH2_k127_3943081_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003597 252.0
CSH2_k127_3943081_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000004397 220.0
CSH2_k127_3943081_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000007658 172.0
CSH2_k127_3943081_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000003296 170.0
CSH2_k127_3943081_6 - - - - 0.0000000000000000000000000000000004295 137.0
CSH2_k127_394316_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 312.0
CSH2_k127_394316_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 289.0
CSH2_k127_394316_2 competence protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001332 228.0
CSH2_k127_394316_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000008215 183.0
CSH2_k127_3950940_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 529.0
CSH2_k127_3950940_1 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 350.0
CSH2_k127_3950940_2 Alpha/beta hydrolase of unknown function (DUF1057) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005819 246.0
CSH2_k127_3950940_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000001357 107.0
CSH2_k127_3950940_4 - - - - 0.000000000001142 75.0
CSH2_k127_4064743_0 PFAM type IV pilus assembly PilZ - - - 0.0000000000000000000004255 102.0
CSH2_k127_4074770_0 Elongation factor Tu domain 2 K03833 - - 1.154e-236 745.0
CSH2_k127_4074770_1 nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 449.0
CSH2_k127_4074770_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000003748 172.0
CSH2_k127_4074770_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000002825 156.0
CSH2_k127_4088441_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 458.0
CSH2_k127_4088441_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 311.0
CSH2_k127_4088441_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000004946 209.0
CSH2_k127_4098514_0 Pfam Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 568.0
CSH2_k127_4098514_1 DNA restriction-modification system K07317 - 2.1.1.72 0.0000000000000005499 79.0
CSH2_k127_4247983_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.323e-205 645.0
CSH2_k127_4247983_1 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 493.0
CSH2_k127_4247983_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K00926 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0033554,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.7.2.2 0.000000000000000000000000007664 110.0
CSH2_k127_4268097_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1026.0
CSH2_k127_4268097_1 Acyl-CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 508.0
CSH2_k127_4268097_2 Putative peptidoglycan binding domain K21470 - - 0.000000004635 63.0
CSH2_k127_4286338_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 360.0
CSH2_k127_4286338_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000119 239.0
CSH2_k127_4286338_2 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000001473 203.0
CSH2_k127_4292104_0 Thiamine pyrophosphate enzyme, central K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 539.0
CSH2_k127_4292104_1 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 417.0
CSH2_k127_4312120_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1054.0
CSH2_k127_4312120_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.807e-291 904.0
CSH2_k127_4312120_2 HD domain - - - 2.552e-196 626.0
CSH2_k127_4312120_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 538.0
CSH2_k127_4312120_4 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 329.0
CSH2_k127_4312120_5 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000004457 267.0
CSH2_k127_4312120_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000856 216.0
CSH2_k127_4312120_7 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000005589 164.0
CSH2_k127_4312120_8 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000007894 114.0
CSH2_k127_4312120_9 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000002622 102.0
CSH2_k127_4352663_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 455.0
CSH2_k127_4352663_1 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 297.0
CSH2_k127_4352663_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000001096 214.0
CSH2_k127_4352663_3 Sulphur transport K07112 - - 0.00000000000001213 73.0
CSH2_k127_4352663_4 viral genome integration into host DNA K04763 - - 0.00004754 45.0
CSH2_k127_4357873_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 378.0
CSH2_k127_4357873_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 363.0
CSH2_k127_4357873_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 283.0
CSH2_k127_4357873_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000004945 180.0
CSH2_k127_4357873_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000001588 169.0
CSH2_k127_4357873_5 KH domain K06960 - - 0.0000000000000000000000000000000000429 134.0
CSH2_k127_4357873_6 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002245 127.0
CSH2_k127_4357873_7 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000002139 113.0
CSH2_k127_4375691_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 550.0
CSH2_k127_4375691_1 SMART AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 495.0
CSH2_k127_4375691_2 PFAM Radical SAM K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 369.0
CSH2_k127_4375691_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 329.0
CSH2_k127_4375691_4 cyclic nucleotide binding K04739,K10914 - - 0.000000000000000000000000000000000005701 143.0
CSH2_k127_4392635_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.531e-256 800.0
CSH2_k127_4392635_1 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 2.098e-226 717.0
CSH2_k127_4392635_2 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 306.0
CSH2_k127_4392635_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000006613 246.0
CSH2_k127_4395545_0 FeoA K04759 - - 4.095e-301 940.0
CSH2_k127_4395968_0 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 562.0
CSH2_k127_4395968_1 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 388.0
CSH2_k127_4395968_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001035 246.0
CSH2_k127_4395968_3 General secretory system II protein E domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000321 222.0
CSH2_k127_4395968_4 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000000000000003438 100.0
CSH2_k127_4395968_5 Protein of unknown function (DUF2845) - - - 0.0002794 47.0
CSH2_k127_4433641_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 8.657e-283 883.0
CSH2_k127_4433641_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 394.0
CSH2_k127_4433641_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 334.0
CSH2_k127_4433641_3 transcription regulator activity K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000003121 207.0
CSH2_k127_4433641_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000004545 176.0
CSH2_k127_4433641_5 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.00000000000000000000000001006 112.0
CSH2_k127_4433641_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000006643 82.0
CSH2_k127_4449301_0 Histidine kinase K02482 - 2.7.13.3 1.684e-252 799.0
CSH2_k127_4449301_1 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003707 282.0
CSH2_k127_4449301_2 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000001508 248.0
CSH2_k127_4449301_3 - - - - 0.00000002429 57.0
CSH2_k127_4455855_0 PFAM magnesium chelatase K07391 - - 7.047e-221 695.0
CSH2_k127_4455855_1 TIGRFAM branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 391.0
CSH2_k127_4455855_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000002785 198.0
CSH2_k127_4455855_3 - - - - 0.00000000000000000000000000000000002474 143.0
CSH2_k127_4455855_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K00972 - 2.7.7.23,2.7.7.83 0.000000000000000000000001351 104.0
CSH2_k127_4455855_5 phosphorelay signal transduction system K07714 - - 0.000000000000000001022 90.0
CSH2_k127_4456946_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 2.376e-279 869.0
CSH2_k127_4456946_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 591.0
CSH2_k127_4456946_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 502.0
CSH2_k127_4456946_3 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 475.0
CSH2_k127_4456946_4 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 447.0
CSH2_k127_4456946_5 bacterial (prokaryotic) histone like domain K04764 - - 0.000000000000000000000000000000000000000000007497 163.0
CSH2_k127_4456946_6 - - - - 0.00000000000000000000000000000000000716 138.0
CSH2_k127_4456946_7 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000000000000000001313 126.0
CSH2_k127_4456946_8 PFAM regulatory protein, MerR - - - 0.0000000000000000000000000000001436 126.0
CSH2_k127_4457730_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.893e-302 936.0
CSH2_k127_4457730_1 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003395 261.0
CSH2_k127_4457730_2 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000000000000000002681 221.0
CSH2_k127_4457730_3 Lipoprotein - - - 0.000002219 50.0
CSH2_k127_4487129_0 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 1.68e-252 788.0
CSH2_k127_4487129_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 458.0
CSH2_k127_4487129_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 371.0
CSH2_k127_4487129_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 353.0
CSH2_k127_4487129_4 WxcM-like, C-terminal K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 281.0
CSH2_k127_4487129_5 PFAM metal-dependent phosphohydrolase, HD sub domain K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000003929 233.0
CSH2_k127_4615946_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 554.0
CSH2_k127_4615946_1 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 413.0
CSH2_k127_4615946_2 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000004849 121.0
CSH2_k127_4615946_3 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000004985 94.0
CSH2_k127_4615946_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000001157 86.0
CSH2_k127_462393_0 NlpC/P60 family K19223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 350.0
CSH2_k127_462393_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 346.0
CSH2_k127_462393_2 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002143 273.0
CSH2_k127_462393_3 TIGRFAM aconitate hydratase K01681 - 4.2.1.3 0.00000000000000000001357 96.0
CSH2_k127_4643612_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 381.0
CSH2_k127_4643612_1 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 319.0
CSH2_k127_4643612_2 NADP oxidoreductase coenzyme F420-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000007932 242.0
CSH2_k127_4655237_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001023 275.0
CSH2_k127_4655237_1 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002904 269.0
CSH2_k127_4683917_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.674e-202 640.0
CSH2_k127_4683917_1 HD domain - - - 0.00000000000000000000000000000000141 134.0
CSH2_k127_4685924_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1082.0
CSH2_k127_4685924_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0002488 47.0
CSH2_k127_470344_0 glycogen debranching enzyme, archaeal type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 604.0
CSH2_k127_470344_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003577 255.0
CSH2_k127_470344_2 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000004704 123.0
CSH2_k127_4741545_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 9.138e-205 642.0
CSH2_k127_4741545_1 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 601.0
CSH2_k127_4741545_2 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 390.0
CSH2_k127_4741545_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 338.0
CSH2_k127_4741545_4 Nucleoside diphosphate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 308.0
CSH2_k127_4741545_5 Cache_2 K08738 - - 0.000000000000000000000000000000000000000000000000000000000006053 209.0
CSH2_k127_4741545_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000005201 52.0
CSH2_k127_4752068_0 FAD dependent oxidoreductase K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 600.0
CSH2_k127_4752068_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 595.0
CSH2_k127_4752068_2 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000005002 203.0
CSH2_k127_4752068_3 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.0000000000000000000000000000000000008119 143.0
CSH2_k127_4752068_4 Universal stress protein family - - - 0.000000000000000000000000002618 116.0
CSH2_k127_4780060_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.891e-256 812.0
CSH2_k127_4780060_1 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 413.0
CSH2_k127_4780060_2 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 319.0
CSH2_k127_4780060_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000005277 233.0
CSH2_k127_4780060_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000002458 157.0
CSH2_k127_4780405_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 516.0
CSH2_k127_4780405_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 516.0
CSH2_k127_4780405_2 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 322.0
CSH2_k127_4780405_3 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001857 276.0
CSH2_k127_4780405_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000006492 245.0
CSH2_k127_4780405_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000009236 201.0
CSH2_k127_4780405_6 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000000006028 176.0
CSH2_k127_4861754_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 477.0
CSH2_k127_4861754_1 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 360.0
CSH2_k127_4861754_2 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000003328 178.0
CSH2_k127_4861754_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000000000000000000000000002041 113.0
CSH2_k127_4861754_4 Helix-turn-helix - - - 0.000003812 51.0
CSH2_k127_4861754_5 PFAM Pilus assembly protein PilO K02664 - - 0.0004035 45.0
CSH2_k127_4902398_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.39e-249 777.0
CSH2_k127_4902398_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 395.0
CSH2_k127_4902398_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 376.0
CSH2_k127_4947531_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 354.0
CSH2_k127_4947531_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 321.0
CSH2_k127_4947531_2 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003309 289.0
CSH2_k127_495755_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001005 265.0
CSH2_k127_495755_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000001275 113.0
CSH2_k127_495755_2 - - - - 0.0000008115 52.0
CSH2_k127_502960_0 Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 299.0
CSH2_k127_502960_1 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000004199 105.0
CSH2_k127_502960_2 Transposase K07483 - - 0.0000000000000002246 82.0
CSH2_k127_502960_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000001026 57.0
CSH2_k127_5092497_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 550.0
CSH2_k127_5092497_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000002928 253.0
CSH2_k127_5092497_2 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000006181 205.0
CSH2_k127_5093227_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 549.0
CSH2_k127_5101927_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.781e-253 785.0
CSH2_k127_5101927_1 Glucosamine-6-phosphate deaminase K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 546.0
CSH2_k127_5101927_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000002063 135.0
CSH2_k127_5110104_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 568.0
CSH2_k127_5110104_1 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 323.0
CSH2_k127_5110104_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000002604 200.0
CSH2_k127_5110104_3 Protein of unknown function (DUF1285) K09986 - - 0.000000000000000000000000000000000000000002475 160.0
CSH2_k127_5126403_0 TIGRFAM leucyl-tRNA synthetase K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1403.0
CSH2_k127_5126403_1 CoA-binding domain protein - - - 2.157e-241 765.0
CSH2_k127_5126403_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000006441 149.0
CSH2_k127_5126403_11 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000003578 101.0
CSH2_k127_5126403_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 2.975e-221 690.0
CSH2_k127_5126403_3 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000426 263.0
CSH2_k127_5126403_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000001773 255.0
CSH2_k127_5126403_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000001016 234.0
CSH2_k127_5126403_6 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000001385 230.0
CSH2_k127_5126403_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000002456 192.0
CSH2_k127_5126403_8 sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000009094 190.0
CSH2_k127_5126403_9 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000000000000000000000005242 173.0
CSH2_k127_5135709_0 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 398.0
CSH2_k127_5142732_0 PFAM short-chain dehydrogenase reductase SDR - - - 4.119e-272 853.0
CSH2_k127_5142732_1 PFAM CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007587 489.0
CSH2_k127_5142732_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001336 271.0
CSH2_k127_5142732_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000007223 204.0
CSH2_k127_5145126_0 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000003508 212.0
CSH2_k127_5145126_1 Glyoxalase-like domain K06996 - - 0.00000000000000002698 82.0
CSH2_k127_5179868_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 3.902e-215 677.0
CSH2_k127_5179868_1 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 429.0
CSH2_k127_5179868_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 304.0
CSH2_k127_5179868_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000001177 80.0
CSH2_k127_5186185_0 General secretory system II protein E domain protein - - - 0.0 1111.0
CSH2_k127_5186185_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.061e-299 932.0
CSH2_k127_5186185_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 578.0
CSH2_k127_5186185_3 PFAM glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 536.0
CSH2_k127_5186185_4 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 475.0
CSH2_k127_5186185_5 MgtE intracellular - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 391.0
CSH2_k127_5186185_6 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004064 278.0
CSH2_k127_5186185_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000004042 154.0
CSH2_k127_5215412_0 AAA domain K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 601.0
CSH2_k127_5215412_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000006737 202.0
CSH2_k127_5215412_2 - - - - 0.000000000000000000000004912 104.0
CSH2_k127_5239394_0 PFAM Type II secretion system protein E K02652 - - 1.044e-214 681.0
CSH2_k127_5239394_1 PFAM type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 476.0
CSH2_k127_5239394_10 - - - - 0.0000000001288 66.0
CSH2_k127_5239394_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 449.0
CSH2_k127_5239394_3 PFAM type II secretion system K02653,K12278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 428.0
CSH2_k127_5239394_4 AAA domain K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 417.0
CSH2_k127_5239394_5 Pilus assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 321.0
CSH2_k127_5239394_6 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000002874 206.0
CSH2_k127_5239394_7 Prokaryotic N-terminal methylation motif - - - 0.000000000001824 73.0
CSH2_k127_5239394_8 - - - - 0.0000000001077 69.0
CSH2_k127_5245857_0 PDZ domain (Also known as DHR or GLGF) K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 483.0
CSH2_k127_5245857_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 472.0
CSH2_k127_5245857_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001579 279.0
CSH2_k127_5245857_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000001687 260.0
CSH2_k127_5245857_4 PFAM Peptidase M22, glycoprotease K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000001219 234.0
CSH2_k127_5245857_5 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000004855 87.0
CSH2_k127_5245857_6 Protein of unknown function (DUF465) K09794 - - 0.0000000000004801 72.0
CSH2_k127_5259659_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000673 271.0
CSH2_k127_5259659_1 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000002488 191.0
CSH2_k127_5259659_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000002987 171.0
CSH2_k127_526690_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 5.79e-205 642.0
CSH2_k127_526690_1 S-layer homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 439.0
CSH2_k127_5276852_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005773 273.0
CSH2_k127_5276852_1 - - - - 0.000000000000000000001403 97.0
CSH2_k127_5368405_0 ABC-type transport system involved in resistance to organic solvents permease component K02066 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 330.0
CSH2_k127_5368405_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 321.0
CSH2_k127_5368405_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 287.0
CSH2_k127_5368405_4 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000001977 221.0
CSH2_k127_5368405_5 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000002276 165.0
CSH2_k127_5368405_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000000000448 151.0
CSH2_k127_5368405_7 Putative regulatory protein - - - 0.0000000000000000000575 90.0
CSH2_k127_5391015_0 PFAM Radical SAM - - - 1.578e-217 687.0
CSH2_k127_5391015_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.457e-199 627.0
CSH2_k127_5391015_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 554.0
CSH2_k127_5391015_3 Essential cell division protein K03589 - - 0.0000000000000000000000000000000000000005671 153.0
CSH2_k127_5451613_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 0.00000000000000000000000000000000000000000000001283 174.0
CSH2_k127_5451613_1 PFAM DRTGG domain K06873 - - 0.000000000000000000000000006202 123.0
CSH2_k127_5451613_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000003514 76.0
CSH2_k127_5509268_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 489.0
CSH2_k127_5509268_1 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005959 290.0
CSH2_k127_5530721_0 PFAM ferredoxin-dependent glutamate synthase - - - 3.671e-294 908.0
CSH2_k127_5530721_1 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 351.0
CSH2_k127_5530721_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 300.0
CSH2_k127_5530721_3 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000004833 168.0
CSH2_k127_5530721_4 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000981 171.0
CSH2_k127_5530721_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000006764 64.0
CSH2_k127_5533788_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 336.0
CSH2_k127_5533788_1 PFAM heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007342 276.0
CSH2_k127_554578_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 522.0
CSH2_k127_554578_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 477.0
CSH2_k127_554578_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002452 277.0
CSH2_k127_554578_3 Secondary thiamine-phosphate synthase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001505 264.0
CSH2_k127_5573084_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 383.0
CSH2_k127_5573084_1 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000003771 183.0
CSH2_k127_5573084_2 Protein of unknown function (DUF721) - - - 0.00005384 48.0
CSH2_k127_5619684_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.379e-217 684.0
CSH2_k127_5619684_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 534.0
CSH2_k127_5619684_2 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 479.0
CSH2_k127_5619684_3 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 385.0
CSH2_k127_5619684_4 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 296.0
CSH2_k127_5619684_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000000000000000007784 224.0
CSH2_k127_5619684_6 TIGRFAM lipopolysaccharide transport periplasmic protein LptA K09774 - - 0.000000000000000000000000000000000000000000000000000000000002045 214.0
CSH2_k127_5619684_7 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000151 198.0
CSH2_k127_5619684_8 HPr Serine kinase C-terminal domain K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000001629 153.0
CSH2_k127_5619684_9 Lipopolysaccharide-assembly, LptC-related - - - 0.000000000000000003513 86.0
CSH2_k127_5791189_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 475.0
CSH2_k127_5791189_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 397.0
CSH2_k127_5791189_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 348.0
CSH2_k127_5791189_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 327.0
CSH2_k127_5791189_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006263 267.0
CSH2_k127_5791189_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000009481 137.0
CSH2_k127_5791328_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2160.0
CSH2_k127_5791328_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1413.0
CSH2_k127_5791328_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 388.0
CSH2_k127_5791328_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003408 251.0
CSH2_k127_5791328_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002175 204.0
CSH2_k127_5791328_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000000004815 201.0
CSH2_k127_5795939_0 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 343.0
CSH2_k127_5795939_1 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 329.0
CSH2_k127_5795939_2 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 309.0
CSH2_k127_5795939_3 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000002274 156.0
CSH2_k127_5920330_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 436.0
CSH2_k127_5920330_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 330.0
CSH2_k127_5920330_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000001469 85.0
CSH2_k127_5943920_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.642e-227 709.0
CSH2_k127_5943920_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 403.0
CSH2_k127_5945434_0 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000001437 205.0
CSH2_k127_5945434_1 ATPases associated with a variety of cellular activities K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000009453 203.0
CSH2_k127_5945434_2 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - 0.000000143 62.0
CSH2_k127_5948488_0 Radical SAM superfamily K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 393.0
CSH2_k127_5948488_1 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 385.0
CSH2_k127_5948488_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 342.0
CSH2_k127_5948488_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 289.0
CSH2_k127_5948488_4 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000294 285.0
CSH2_k127_5948488_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.000000000000000000000000000000000000001102 151.0
CSH2_k127_5948488_6 Thioredoxin-like - - - 0.000000000000000000002728 107.0
CSH2_k127_5962637_0 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 448.0
CSH2_k127_5962637_1 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 311.0
CSH2_k127_5962637_2 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000001856 177.0
CSH2_k127_5962637_4 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000003062 124.0
CSH2_k127_5962637_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000001246 53.0
CSH2_k127_5971437_0 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 383.0
CSH2_k127_5971437_1 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000121 231.0
CSH2_k127_5971437_2 Belongs to the 5'-nucleotidase family - - - 0.000000005078 66.0
CSH2_k127_5975549_0 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 421.0
CSH2_k127_5975549_1 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 407.0
CSH2_k127_5975549_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 312.0
CSH2_k127_5975549_3 dUTPase K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000007078 205.0
CSH2_k127_5976595_0 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 383.0
CSH2_k127_5976595_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000001281 190.0
CSH2_k127_5976595_2 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000001971 144.0
CSH2_k127_5983973_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000003234 222.0
CSH2_k127_5983973_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000008374 145.0
CSH2_k127_5983973_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000001515 109.0
CSH2_k127_5990386_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 562.0
CSH2_k127_5990386_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 325.0
CSH2_k127_5990386_2 CBS domain containing protein K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001824 254.0
CSH2_k127_5990713_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 8.584e-218 683.0
CSH2_k127_5990713_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 432.0
CSH2_k127_5990713_2 Predicted membrane protein (DUF2232) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004281 257.0
CSH2_k127_5990713_3 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000013 186.0
CSH2_k127_5990713_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000007745 126.0
CSH2_k127_5990713_5 Diadenylate cyclase - - - 0.00000000000000000000000000002103 123.0
CSH2_k127_5990713_6 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000115 117.0
CSH2_k127_6009110_0 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 4.159e-198 621.0
CSH2_k127_6009110_1 - - - - 0.0000000000000000000000000000003232 125.0
CSH2_k127_6009110_2 Cytidylate kinase-like family - - - 0.00000000000000006648 85.0
CSH2_k127_6009110_3 Antibiotic biosynthesis monooxygenase - - - 0.000000000001173 72.0
CSH2_k127_6009891_0 Ftsk_gamma K03466 - - 2.11e-264 833.0
CSH2_k127_6009891_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 291.0
CSH2_k127_6009891_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00007283 48.0
CSH2_k127_6012940_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 5.303e-250 775.0
CSH2_k127_6012940_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 507.0
CSH2_k127_6012940_10 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006694 242.0
CSH2_k127_6012940_11 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000003164 224.0
CSH2_k127_6012940_12 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001718 222.0
CSH2_k127_6012940_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001043 217.0
CSH2_k127_6012940_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000007834 217.0
CSH2_k127_6012940_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000004017 209.0
CSH2_k127_6012940_16 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001895 200.0
CSH2_k127_6012940_17 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000005094 178.0
CSH2_k127_6012940_18 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000002716 172.0
CSH2_k127_6012940_19 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000009698 171.0
CSH2_k127_6012940_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 461.0
CSH2_k127_6012940_20 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000002015 165.0
CSH2_k127_6012940_21 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000001718 154.0
CSH2_k127_6012940_22 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001004 150.0
CSH2_k127_6012940_23 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000005783 146.0
CSH2_k127_6012940_24 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000004175 127.0
CSH2_k127_6012940_25 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001492 118.0
CSH2_k127_6012940_26 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001993 109.0
CSH2_k127_6012940_27 Ribosomal protein L30p/L7e K02907 - - 0.000000000000000000666 87.0
CSH2_k127_6012940_28 peptidase U32 - - - 0.000000000000003105 81.0
CSH2_k127_6012940_29 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002292 72.0
CSH2_k127_6012940_3 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 366.0
CSH2_k127_6012940_30 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000008397 64.0
CSH2_k127_6012940_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 344.0
CSH2_k127_6012940_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 343.0
CSH2_k127_6012940_6 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 303.0
CSH2_k127_6012940_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 284.0
CSH2_k127_6012940_8 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000764 262.0
CSH2_k127_6012940_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000008553 243.0
CSH2_k127_6025246_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 469.0
CSH2_k127_6025246_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 379.0
CSH2_k127_6025246_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000056 199.0
CSH2_k127_6025246_3 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000001251 147.0
CSH2_k127_6025246_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000001972 117.0
CSH2_k127_6027826_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 485.0
CSH2_k127_6027826_1 Belongs to the 3-oxoacid CoA-transferase family K01026 - 2.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 468.0
CSH2_k127_6028299_0 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 351.0
CSH2_k127_6028299_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 353.0
CSH2_k127_6028299_2 tRNA 3'-trailer cleavage - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 329.0
CSH2_k127_6028299_3 RNA polymerase sigma factor K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000385 254.0
CSH2_k127_6028299_4 Histidine kinase - - - 0.00000000000000000000000000000000000000005452 161.0
CSH2_k127_6028299_5 PFAM Anti-sigma-28 factor FlgM family protein K02398 - - 0.0007322 46.0
CSH2_k127_6032894_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.158e-227 713.0
CSH2_k127_6032894_1 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 601.0
CSH2_k127_6032894_2 thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 361.0
CSH2_k127_6073736_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 569.0
CSH2_k127_6073736_1 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 524.0
CSH2_k127_6073736_2 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 368.0
CSH2_k127_6073736_3 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 307.0
CSH2_k127_6073736_4 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005852 272.0
CSH2_k127_6103969_0 Elongation factor Tu domain 2 K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 537.0
CSH2_k127_6103969_1 molybdenum cofactor K03638,K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000287 246.0
CSH2_k127_6103969_2 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000001574 111.0
CSH2_k127_6104585_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 539.0
CSH2_k127_6104585_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 342.0
CSH2_k127_6104585_2 Domain of unknown function (DUF4922) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 305.0
CSH2_k127_6104585_3 Protein of unknown function (DUF1460) - - - 0.000000000000000000000000000000000000000000000000000000000000001707 227.0
CSH2_k127_6104585_4 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000005621 218.0
CSH2_k127_6104585_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000582 111.0
CSH2_k127_6104585_6 - - - - 0.00000000000000000006548 91.0
CSH2_k127_6104585_7 nucleic acid-binding protein contains PIN domain - - - 0.0002817 44.0
CSH2_k127_6160527_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 3.884e-211 666.0
CSH2_k127_6160527_1 Jag_N K06346 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 293.0
CSH2_k127_6160527_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000001791 50.0
CSH2_k127_6163815_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 494.0
CSH2_k127_6163815_1 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 396.0
CSH2_k127_6163815_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000000001323 231.0
CSH2_k127_6163815_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000007264 184.0
CSH2_k127_6163815_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000002009 133.0
CSH2_k127_6163815_5 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000001282 111.0
CSH2_k127_6163815_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000001827 91.0
CSH2_k127_61669_0 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 560.0
CSH2_k127_61669_1 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 401.0
CSH2_k127_61669_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 376.0
CSH2_k127_61669_3 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 292.0
CSH2_k127_61669_4 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000008805 244.0
CSH2_k127_61669_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000003522 220.0
CSH2_k127_61669_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000001245 196.0
CSH2_k127_61669_7 Belongs to the bacterial histone-like protein family K05788 - - 0.00000000000000000000000000001765 117.0
CSH2_k127_61669_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000005334 119.0
CSH2_k127_6173239_0 Thymidylate synthase complementing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 570.0
CSH2_k127_6173239_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 476.0
CSH2_k127_6173239_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 408.0
CSH2_k127_6173239_3 Protein of unknown function DUF47 K07220 - - 0.000000000000000001202 85.0
CSH2_k127_6184136_0 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 314.0
CSH2_k127_6184136_1 Beta-lactamase superfamily domain K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 310.0
CSH2_k127_6184136_2 Helicase associated domain (HA2) Add an annotation K03578,K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000006849 227.0
CSH2_k127_6184136_3 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000005016 186.0
CSH2_k127_6184136_4 Belongs to the phosphoglycerate mutase family K22305 - 3.1.3.3 0.0000000000000000000000000000000004237 139.0
CSH2_k127_6188361_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1177.0
CSH2_k127_6188361_1 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 347.0
CSH2_k127_6188361_2 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000003549 176.0
CSH2_k127_6188361_3 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000003735 52.0
CSH2_k127_6193030_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 418.0
CSH2_k127_6193030_1 Rhs element Vgr protein K11904 - - 0.00000000000000000000000000001289 126.0
CSH2_k127_6193030_2 PFAM regulatory protein LuxR - - - 0.000000000000000000000000009796 111.0
CSH2_k127_6193030_3 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000002872 109.0
CSH2_k127_6208246_0 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000108 235.0
CSH2_k127_6208246_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000002626 228.0
CSH2_k127_6208246_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000000001385 156.0
CSH2_k127_6208246_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000001091 93.0
CSH2_k127_6213414_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 387.0
CSH2_k127_6213414_1 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004422 254.0
CSH2_k127_6213414_2 PFAM phosphoesterase RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000246 228.0
CSH2_k127_6214575_0 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 589.0
CSH2_k127_6214575_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 425.0
CSH2_k127_6214575_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003757 278.0
CSH2_k127_6283960_0 Participates in both transcription termination and antitermination K02600 - - 1.409e-207 651.0
CSH2_k127_6283960_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000000000000000000000177 215.0
CSH2_k127_6283960_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000004855 180.0
CSH2_k127_6306244_0 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000003464 217.0
CSH2_k127_6306244_1 peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000009477 107.0
CSH2_k127_6317990_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 496.0
CSH2_k127_6317990_1 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 486.0
CSH2_k127_6317990_2 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 307.0
CSH2_k127_6317990_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000028 153.0
CSH2_k127_6317990_4 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000002434 72.0
CSH2_k127_6317990_5 DsrE/DsrF-like family K04085 - - 0.000000000004794 68.0
CSH2_k127_6352712_0 PFAM CoA-binding domain protein - - - 5.89e-244 773.0
CSH2_k127_6352712_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 302.0
CSH2_k127_6352712_2 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000007052 207.0
CSH2_k127_6352712_3 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000005871 135.0
CSH2_k127_6352712_4 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000000000000000000005269 120.0
CSH2_k127_6352712_5 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000002549 68.0
CSH2_k127_6362756_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 497.0
CSH2_k127_6362756_1 Gtr1/RagA G protein conserved region K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 292.0
CSH2_k127_6362756_2 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000001477 136.0
CSH2_k127_6362756_3 MJ0042 family finger-like protein - - - 0.000000000000000000000001453 116.0
CSH2_k127_6362756_4 - K08086 - - 0.000000000000000009087 96.0
CSH2_k127_6362756_5 Domain of unknown function (DUF4388) - - - 0.00000000000000002021 92.0
CSH2_k127_6362756_6 stage II sporulation protein D K06381 - - 0.000000000000001234 78.0
CSH2_k127_6372723_0 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 380.0
CSH2_k127_6372723_1 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000195 232.0
CSH2_k127_6372723_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000004211 188.0
CSH2_k127_6372723_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000002408 180.0
CSH2_k127_6372723_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000004087 154.0
CSH2_k127_6372723_5 Pfam:N_methyl_2 - - - 0.00000001669 64.0
CSH2_k127_6372723_6 Prokaryotic N-terminal methylation motif K08084,K08085 - - 0.0005437 49.0
CSH2_k127_6372930_0 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000007676 70.0
CSH2_k127_6372930_1 - - - - 0.000001597 61.0
CSH2_k127_642604_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 507.0
CSH2_k127_642604_1 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000000000000000001944 151.0
CSH2_k127_6452493_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000009525 222.0
CSH2_k127_6452493_2 Polymer-forming cytoskeletal - - - 0.000000000000003178 79.0
CSH2_k127_6452493_3 - - - - 0.0000000007721 68.0
CSH2_k127_6477863_0 Tetraprenyl-beta-curcumene synthase K16188 - 4.2.3.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 496.0
CSH2_k127_6477863_1 Histidine kinase HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 440.0
CSH2_k127_6477863_2 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001156 247.0
CSH2_k127_6478513_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 526.0
CSH2_k127_6478513_1 SMART Elongator protein 3 MiaB NifB K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 439.0
CSH2_k127_6478513_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000007693 171.0
CSH2_k127_6528944_0 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 544.0
CSH2_k127_6528944_1 Signal transduction histidine kinase, nitrogen specific - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 469.0
CSH2_k127_6528944_3 PFAM Acyl-CoA dehydrogenase K00249,K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11,1.3.8.7 0.0004736 42.0
CSH2_k127_693693_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 452.0
CSH2_k127_693693_1 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 437.0
CSH2_k127_693693_2 Serine Threonine protein kinase K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000001349 186.0
CSH2_k127_693693_3 PFAM Uncharacterised BCR, COG1649 K01448 - 3.5.1.28 0.00000000000000000000000000000000001536 143.0
CSH2_k127_693693_4 peptidyl-tyrosine sulfation - - - 0.000000000000000002997 98.0
CSH2_k127_693693_5 COG0183 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.0000000001437 66.0
CSH2_k127_82533_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 372.0
CSH2_k127_82533_1 citrate synthase K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 356.0
CSH2_k127_82533_2 Uncharacterized BCR, YaiI/YqxD family COG1671 K09768 - - 0.00000000000000000000000000000000000000000000008498 172.0
CSH2_k127_82533_3 conserved protein (DUF2196) - - - 0.0000000000000000000003519 96.0
CSH2_k127_82533_4 - - - - 0.0000000000000000007532 91.0
CSH2_k127_849537_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 610.0
CSH2_k127_849537_1 Na+/Pi-cotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000375 270.0
CSH2_k127_849537_2 Polyketide synthase dehydratase - - - 0.000005002 50.0
CSH2_k127_860183_0 Peptidase M16C associated K06972 - - 3.278e-293 917.0
CSH2_k127_860183_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000000002282 231.0
CSH2_k127_882793_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 394.0
CSH2_k127_882793_1 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 298.0
CSH2_k127_882793_2 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 296.0
CSH2_k127_882793_3 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000004201 202.0
CSH2_k127_882793_4 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000005336 181.0
CSH2_k127_882793_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000109 113.0
CSH2_k127_898589_0 Ferrous iron transport protein B K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 479.0
CSH2_k127_898589_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 372.0
CSH2_k127_898589_2 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000008789 228.0
CSH2_k127_898589_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000007793 216.0
CSH2_k127_898589_4 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000002209 213.0
CSH2_k127_898589_5 - - - - 0.000000000000284 78.0
CSH2_k127_898589_6 type IV pilus assembly PilZ - - - 0.00000000003963 70.0
CSH2_k127_904218_0 Stage II sporulation K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 539.0
CSH2_k127_904218_1 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000002339 187.0
CSH2_k127_904218_2 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000009413 117.0
CSH2_k127_904218_3 transporter antisigma-factor antagonist STAS K04749 - - 0.0000000000000000000000001643 109.0
CSH2_k127_904218_4 PFAM NMT1 THI5 like K02051 - - 0.0000000000000000006558 88.0
CSH2_k127_92106_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 9.319e-212 664.0
CSH2_k127_92106_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 577.0
CSH2_k127_92106_2 MltA-interacting protein MipA - - - 0.000000000000000000000000000000000000000000000000000000000000000000001428 245.0
CSH2_k127_964249_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 520.0
CSH2_k127_964249_1 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 328.0
CSH2_k127_964249_2 PFAM NAD(P)H dehydrogenase (quinone) K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 291.0
CSH2_k127_964249_3 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001026 236.0
CSH2_k127_964249_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000389 218.0
CSH2_k127_964249_5 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000001156 186.0
CSH2_k127_964249_6 EXOIII K13288 - - 0.0000000000001667 78.0
CSH2_k127_964249_7 ribonuclease BN - - - 0.00000000001892 65.0
CSH2_k127_964249_8 SNARE associated Golgi protein - - - 0.00000000129 59.0
CSH2_k127_990272_0 PFAM Pyruvate carboxyltransferase - - - 0.0 1042.0
CSH2_k127_990272_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 584.0
CSH2_k127_990272_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 302.0